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$259+ Cheap flights from South Carolina to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ROM
Mar 2 — Mar 91
Mon 3/2
Mon 3/9
1 adult, Economy
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Cheap flight deals from South Carolina to Rome

Cheapest flights from South Carolina to Rome
Explore the most affordable flight options available from South Carolina to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 31, 2026.

This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:36 pm
CAE
-
FCO
1 stop30h 54m
United Airlines
Mon 3/910:15 am
FCO
-
CAE
2 stops42h 29m
United Airlines
Deal found 1/31$494
This Cheapflightsfares deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:32 pm
GSP
-
FCO
2 stops19h 43m
Lufthansa
Wed 3/187:05 am
FCO
-
GSP
2 stops21h 54m
Lufthansa
Deal found 1/30$496
This KLM deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/13:09 pm
CAE
-
FCO
1 stop13h 21m
KLM
Mon 3/99:05 am
FCO
-
CAE
1 stop19h 43m
KLM
Deal found 1/30$500
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:48 pm
CHS
-
FCO
2 stops20h 22m
United Airlines
Mon 3/910:15 am
FCO
-
CHS
2 stops40h 01m
United Airlines
Deal found 1/30$503
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:36 pm
CAE
-
FCO
2 stops33h 24m
United Airlines
Mon 3/97:05 am
FCO
-
CAE
2 stops31h 56m
United Airlines
Deal found 1/30$507
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:40 am
CLT
-
FCO
1 stop17h 55m
Delta
Sat 8/299:45 am
FCO
-
CLT
1 stop15h 38m
Delta
Deal found 1/28$508
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:20 pm
SAV
-
FCO
1 stop31h 10m
United Airlines
Sat 3/79:40 am
FCO
-
SAV
2 stops16h 20m
United Airlines
Deal found 1/30$508
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:00 am
GSP
-
FCO
1 stop16h 30m
United Airlines
Sun 3/19:45 am
FCO
-
GSP
1 stop30h 16m
United Airlines
Deal found 1/28$508
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:30 pm
CLT
-
FCO
1 stop12h 20m
Delta
Thu 8/276:30 am
FCO
-
CLT
2 stops23h 27m
Delta
Deal found 1/28$509
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:00 am
GSP
-
FCO
1 stop16h 30m
United Airlines
Tue 3/1711:00 am
FCO
-
GSP
1 stop13h 28m
United Airlines
Deal found 1/30$509
This oojo deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
GSP
-
FCO
2 stops31h 35m
British Airways
Fri 3/65:50 pm
FCO
-
GSP
2 stops33h 23m
British Airways
Deal found 1/30$511
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:02 pm
CHS
-
FCO
2 stops14h 53m
Delta
Mon 3/99:05 am
FCO
-
CHS
1 stop14h 54m
Delta
Deal found 1/30$513

Find flight deals from South Carolina to Rome

Keep the following information in mind while searching for South Carolina to Rome flight deals. Data was last updated January 31, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$494
(United Airlines)

One-way from

$259
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$519
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Rome (ROM)
Search Deals
One-way flight from South Carolina to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($428 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($67 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 31, 2026.
Use the filters below to find and compare flights from South Carolina to Rome that are best for you.

Fly from

South Carolina

Fly to

Rome

Route

Depart

Return

Price

ColumbiaRome

CAE - FCO

CAEFCO

Columbia Metropolitan

Tue 3/3

7:36 pm-8:30 am

1 stop30h 54m

Rome Fiumicino

Mon 3/9

10:15 am-11:44 pm

2 stops42h 29m

$494

ColumbiaRome

CAE - FCO

CAEFCO

Columbia Metropolitan

Sun 3/1

3:09 pm-10:30 am

1 stop13h 21m

Rome Fiumicino

Mon 3/9

8:20 am-7:58 pm

2 stops16h 38m

$500

ColumbiaRome

CAE - FCO

CAEFCO

Columbia Metropolitan

Sun 3/1

7:36 pm-11:00 am

2 stops33h 24m

Rome Fiumicino

Mon 3/9

7:05 am-10:01 am

2 stops31h 56m

$507

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Fri 2/27

7:20 pm-8:30 am

1 stop31h 10m

Rome Fiumicino

Sat 3/7

9:40 am-8:00 pm

2 stops16h 20m

$508

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

Wed 2/25

10:00 am-8:30 am

1 stop16h 30m

Rome Fiumicino

Sun 3/1

9:45 am-10:01 am

1 stop30h 16m

$508

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

Mon 3/2

6:30 am-7:45 am

1 stop19h 15m

Rome Fiumicino

Tue 3/17

7:05 am-7:28 pm

2 stops17h 23m

$508

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

Mon 3/9

5:40 am-6:05 am

2 stops19h 25m

Rome Fiumicino

Wed 3/18

9:05 am-11:54 pm

1 stop19h 49m

$513

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

Mon 3/9

7:59 pm-9:30 am

1 stop32h 31m

Rome Fiumicino

Wed 3/18

9:05 am-11:54 pm

1 stop19h 49m

$514

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

Sun 3/1

6:13 am-12:25 pm

2 stops24h 12m

Rome Fiumicino

Sat 3/7

5:50 pm-9:44 am

2 stops45h 54m

$516

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Mon 3/16

9:50 am-11:00 am

2 stops20h 10m

Rome Fiumicino

Wed 3/25

7:05 am-7:13 pm

2 stops17h 08m

$516

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/31

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Rome

What is the cheapest month to book a flight from South Carolina to Rome?

Currently, December is the cheapest month in which you can book a flight from South Carolina to Rome (average of $307). Flying from South Carolina to Rome in July is currently the most expensive (average of $859). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to ROM?

Find hourly flight availability from South Carolina to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 31, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 33% on flights from South Carolina to Rome by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Rome?

    United Airlines, KLM, and Delta can get you from South Carolina to Rome in just under 13h 21m. Your travel time can differ by up to 17h 33m. Airlines will cover a distance of 4860 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Rome?

    The most popular route from South Carolina to Rome is Charlotte Douglas - Rome Fiumicino. You may also consider Greenville - Rome Fiumicino or Charleston - Rome Fiumicino.

  • Can I find deals for flights from South Carolina to Rome that include hotel bookings?

    Yes. In addition to deals on South Carolina to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Rome.

  • Can I find deals for business class flights from South Carolina to Rome?

    Yes. Cheapflights offers flight deals from South Carolina to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Rome?

    Currently, December is the cheapest month in which you can book a flight from South Carolina to Rome (average of $307). Flying from South Carolina to Rome in July is currently the most expensive (average of $859). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for South Carolina to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Rome

Discover the top 5 airlines that operate flights from South Carolina to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 31, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,228FlexibilityNo cancel feeOn-time69%
DeltaCheapest$457Average$1,058FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$507Average$1,078FlexibilityNo cancel feeOn-time75%
British AirwaysCheapest$609Average$1,020FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$704Average$1,124FlexibilityNo cancel feeOn-time71%

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