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$224+ Cheap flights from South Carolina to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ROM
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from South Carolina to Rome

Cheapest flights from South Carolina to Rome
Explore the most affordable flight options available from South Carolina to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:54 pmCLT - FCO
1 stop11h 36mMultiple Airlines
Sat 1/109:35 amFCO - CLT
2 stops17h 22mMultiple Airlines
Deal found 12/16$763
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:54 pmCLT - FCO
1 stop11h 36mLufthansa
Sat 1/107:00 amFCO - CLT
1 stop15h 55mLufthansa
Deal found 12/16$779
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:44 pmCLT - FCO
1 stop30h 46mMultiple Airlines
Thu 1/88:15 pmFCO - CLT
2 stops50h 40mMultiple Airlines
Deal found 12/16$788
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:44 pmCLT - FCO
1 stop30h 46mLufthansa
Thu 1/87:05 pmFCO - CLT
1 stop27h 50mLufthansa
Deal found 12/16$844
This oojo deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:00 pmCLT - FCO
1 stop16h 55mBritish Airways
Thu 1/85:50 pmFCO - CLT
1 stop26h 25mBritish Airways
Deal found 12/17$957
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:15 amCLT - FCO
2 stops15h 15mUnited Airlines
Sat 1/107:05 amFCO - CLT
2 stops15h 50mUnited Airlines
Deal found 12/16$973
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:00 pmCLT - FCO
2 stops19h 15mIberia
Thu 1/87:10 pmFCO - CLT
2 stops29h 55mIberia
Deal found 12/16$1,017
This Ovago deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:21 pmCLT - FCO
1 stop30h 39mBritish Airways
Sun 12/2811:00 amFCO - CLT
1 stop18h 25mBritish Airways
Deal found 12/16$1,124
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:30 amCLT - FCO
2 stops31h 30mUnited Airlines
Tue 12/301:10 pmFCO - CLT
2 stops26h 53mUnited Airlines
Deal found 12/16$1,126
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:18 pmCHS - FCO
2 stops34h 12mMultiple Airlines
Mon 1/57:10 pmFCO - CHS
1 stop24h 00mMultiple Airlines
Deal found 12/16$1,300
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:15 pmCHS - FCO
1 stop18h 15mMultiple Airlines
Mon 1/57:10 pmFCO - CHS
1 stop24h 00mMultiple Airlines
Deal found 12/16$1,318
This Trip.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:16 amCHS - FCO
1 stop21h 14mMultiple Airlines
Mon 1/57:10 pmFCO - CHS
2 stops22h 18mMultiple Airlines
Deal found 12/16$1,426

Find flight deals from South Carolina to Rome

Keep the following information in mind while searching for South Carolina to Rome flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$437
(Kiwi.com)

One-way from

$224
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$1,511
Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.
Search Deals
From South Carolina to Rome (ROM)
Search Deals
One-way flight from South Carolina to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($402 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($68 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Carolina to Rome that are best for you.

Fly from

South Carolina

Fly to

Rome

Route

Depart

Return

Price

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Sat 1/31

2:05 pm-7:55 am

1 stop11h 50m

Rome Fiumicino

Mon 2/9

11:00 am-7:25 pm

1 stop14h 25m

$481

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Sat 1/31

2:05 pm-7:55 am

1 stop11h 50m

Rome Fiumicino

Mon 2/9

8:25 am-7:25 pm

2 stops17h 00m

$486

GreenvilleRome

GSP - FCO

GSPFCO

Greenville

Wed 2/4

11:50 am-7:55 am

1 stop14h 05m

Rome Fiumicino

Wed 2/11

10:30 am-11:48 pm

1 stop19h 18m

$486

Myrtle BeachRome

MYR - FCO

MYRFCO

Myrtle Beach Intl

Sat 1/31

1:13 pm-7:55 am

1 stop12h 42m

Rome Fiumicino

Sat 2/7

11:15 am-12:41 pm

2 stops31h 26m

$487

Myrtle BeachRome

MYR - FCO

MYRFCO

Myrtle Beach Intl

Fri 1/23

1:25 pm-7:55 am

1 stop12h 30m

Rome Fiumicino

Mon 1/26

11:15 am-12:41 pm

2 stops31h 26m

$487

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Sat 1/31

2:05 pm-7:55 am

1 stop11h 50m

Rome Fiumicino

Sat 2/7

11:15 am-9:36 pm

2 stops40h 21m

$487

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Tue 3/3

1:11 pm-7:45 am

1 stop12h 34m

Rome Fiumicino

Mon 3/9

10:15 am-1:52 pm

2 stops32h 37m

$491

ColumbiaRome

CAE - FCO

CAEFCO

Columbia Metropolitan

Wed 2/4

7:30 pm-8:30 am

1 stop31h 00m

Rome Fiumicino

Sun 2/8

12:45 pm-10:17 am

2 stops51h 32m

$491

ColumbiaRome

CAE - FCO

CAEFCO

Columbia Metropolitan

Tue 3/3

3:32 pm-6:15 pm

2 stops20h 43m

Rome Fiumicino

Mon 3/9

9:45 am-8:50 pm

1 stop16h 05m

$493

SavannahRome

SAV - FCO

SAVFCO

Savannah/Hilton Head

Fri 1/30

6:40 am-9:25 am

2 stops20h 45m

Rome Fiumicino

Sun 2/8

12:45 pm-10:46 pm

2 stops40h 01m

$494

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Rome

What is the cheapest month to book a flight from South Carolina to Rome?

Currently, December is the cheapest month in which you can book a flight from South Carolina to Rome (average of $307). Flying from South Carolina to Rome in July is currently the most expensive (average of $859). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to ROM?

Find hourly flight availability from South Carolina to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 18% on flights from South Carolina to Rome by exploring options for tickets in the evening.

What is the cheapest day to fly from South Carolina to Rome?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Rome. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Rome flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Rome?

    Lufthansa, United Airlines, and Delta can get you from South Carolina to Rome in just under 11h 50m. Your travel time can differ by up to 5h 40m. Airlines will cover a distance of 4941 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Rome?

    The most popular route from South Carolina to Rome is Charlotte Douglas - Rome Fiumicino. You may also consider Charleston - Rome Fiumicino or Greenville - Rome Fiumicino.

  • Can I find deals for flights from South Carolina to Rome that include hotel bookings?

    Yes. In addition to deals on South Carolina to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Rome.

  • Can I find deals for business class flights from South Carolina to Rome?

    Yes. Cheapflights offers flight deals from South Carolina to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Rome?

    Currently, December is the cheapest month in which you can book a flight from South Carolina to Rome (average of $307). Flying from South Carolina to Rome in July is currently the most expensive (average of $859). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for South Carolina to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Rome

Discover the top 5 airlines that operate flights from South Carolina to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$1,128FlexibilityNo cancel feeOn-time69%
KLMCheapest$555Average$1,092FlexibilityNo cancel feeOn-time75%
DeltaCheapest$555Average$1,049FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$609Average$1,029FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$725Average$1,232FlexibilityNo cancel feeOn-time71%

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