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$543+ Cheap flights from Panama City (PTY) to Rome (ROM)

PTY — ROM
Oct 6 — Oct 131
Tue 10/6
Tue 10/13
1 adult, Economy
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Cheap flight deals from Panama City to Rome

Cheapest flights from Panama City to Rome

Mon 11/99:30 pm -
1 stop13h 55m
Mon 11/2310:30 am -
1 stop15h 15m
Deal found 9/2$800
Sat 10/249:30 pm -
1 stop13h 55m
Fri 11/203:55 pm -
1 stop33h 50m
Deal found 9/4$812
Fri 11/136:35 pm -
1 stop17h 35m
Thu 11/264:20 pm -
1 stop30h 45m
Deal found 9/3$827
Mon 10/269:30 pm -
1 stop13h 55m
Mon 11/210:30 am -
1 stop15h 15m
Deal found 9/3$833
Thu 11/129:30 pm -
1 stop13h 55m
Thu 11/2610:30 am -
1 stop15h 15m
Deal found 9/6$834
Wed 11/119:30 pm -
1 stop35h 25m
Mon 11/2310:30 am -
1 stop15h 15m
Deal found 9/2$842
Thu 10/299:30 pm -
1 stop13h 55m
Tue 11/106:25 pm -
1 stop31h 20m
Deal found 9/3$843

Find flight deals from Panama City to Rome

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$703
(Iberia)

One-way from

$543
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$944
Provider with most accurate pricing for Panama City Tocumen Intl-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Rome (ROM) flights.
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From Panama City Tocumen Intl to Rome (ROM)
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One-way flight from Panama City Tocumen Intl to Rome (ROM)
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Highest demand for flights based on searches. 12% potential increase in price ($135 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

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Cheapest round-trip

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Sat 10/31

9:00 am-12:35 pm

1 stop21h 35m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$543
Quickest round-trip

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Fri 10/30

9:30 pm-5:25 pm

1 stop13h 55m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$581

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Wed 10/28

9:30 pm-9:30 am

1 stop30h 00m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$604

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Sun 10/4

10:25 am-10:00 pm

3 stops28h 35m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$656

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Tue 9/29

9:33 pm-10:50 pm

3 stops42h 17m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$678

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Tue 10/6

8:10 pm-11:35 pm

1 stop20h 25m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$685

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Tue 10/6

12:23 pm-8:55 am

2 stops37h 32m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$714

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Fri 10/30

4:25 pm-3:00 pm

2 stops16h 35m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$748

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Thu 10/29

9:30 pm-5:25 pm

1 stop13h 55m

Rome Fiumicino

Tue 11/10

3:55 pm-7:45 pm

1 stop33h 50m

$813

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Sun 12/13

4:10 pm-1:25 pm

2 stops39h 15m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$824

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/1

Showing 1-10 of 21 resultsSorted by cheapest first
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  • Most accurate provider: When it comes to deals on Panama City-Rome flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Rome flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Rome flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

What is the cheapest month to book a flight from Panama City to Rome?

Currently, April is the cheapest month in which you can book a flight from Panama City to Rome (average of $716). Flying from Panama City to Rome in July is currently the most expensive (average of $1,150). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Rome?

Airfare is below average for this route at the moment.
Panama City to Rome flights typically cost between $796 and $1,148 in February.
The cheapest round-trip price found within the last 5 days was $703 on Iberia (Feb 17-Feb 28).

How far ahead should I book a flight from Panama City to Rome?

The price you pay for your flight from Panama City to Rome may vary depending on when you book. For the best chance of a lower fare, look to book 14 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Rome

Read reviews from past customers who have flown Turkish Airlines and Air Europa from Panama City to Rome. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.4
Good
4,476 reviews

Crew

7.8

Food

7.5

Overall

7.4

Entertainment

7.5

Comfort

7.3

Boarding

7.3

Reviews

1 / 20
2.0
Mediocre

Michael,Nov 2024

IST - DTW

We arrived early and checked in. The lady at the counter was very rude to us, we believe it’s because we are a mixed race couple. I asked if we could upgrade our seats and she immediately said no upgrades. We walked away with our boarding passes without looking at them. Later we look at passes and she changed my seat. Now we’re not sitting together after my husband bought our seats. We were assigned 9A and 9B, which we paid for. Now I’m in 9E. I went to the care point counter and the person who helped me said she couldn’t put me next to my husband, because he didn’t purchase 9A. I showed her our paperwork and the price we paid for the seats and her response was there’s nothing she could do. I then waited to speak with someone at the gate. The person I spoke with looked at our receipt and changed my seat to 9C. As we’re sitting waiting for boarding I needed to use the restroom, but the person who was there for security pulled the retractable belt barrier right in front of me and said I needed to hold it. I stood there for 5 minutes and then just sat back down…no one even walked by. I did Not like the way that I was treated and we will never fly Turkish Airlines again. If a trip we’re taking causes us to fly Turkish, I would have to think do I want to be treated this way again. There’s no reason to be treated this way Ever. Shame on Turkish!
Turkish Airlines
7.4
Good
4,476 reviews
Turkish Airlines
7.4
Good
4,476 reviews

Crew

7.8

Food

7.5

Overall

7.4

Entertainment

7.5

Comfort

7.3

Boarding

7.3

Reviews

1 / 20
2.0
Mediocre

Michael,Nov 2024

IST - DTW

We arrived early and checked in. The lady at the counter was very rude to us, we believe it’s because we are a mixed race couple. I asked if we could upgrade our seats and she immediately said no upgrades. We walked away with our boarding passes without looking at them. Later we look at passes and she changed my seat. Now we’re not sitting together after my husband bought our seats. We were assigned 9A and 9B, which we paid for. Now I’m in 9E. I went to the care point counter and the person who helped me said she couldn’t put me next to my husband, because he didn’t purchase 9A. I showed her our paperwork and the price we paid for the seats and her response was there’s nothing she could do. I then waited to speak with someone at the gate. The person I spoke with looked at our receipt and changed my seat to 9C. As we’re sitting waiting for boarding I needed to use the restroom, but the person who was there for security pulled the retractable belt barrier right in front of me and said I needed to hold it. I stood there for 5 minutes and then just sat back down…no one even walked by. I did Not like the way that I was treated and we will never fly Turkish Airlines again. If a trip we’re taking causes us to fly Turkish, I would have to think do I want to be treated this way again. There’s no reason to be treated this way Ever. Shame on Turkish!
Air Europa
7.0
Good
635 reviews
Turkish Airlines
7.4
Good
4,476 reviews

Crew

7.8

Food

7.5

Overall

7.4

Entertainment

7.5

Comfort

7.3

Boarding

7.3

Reviews

1 / 20
2.0
Mediocre

Michael,Nov 2024

IST - DTW

We arrived early and checked in. The lady at the counter was very rude to us, we believe it’s because we are a mixed race couple. I asked if we could upgrade our seats and she immediately said no upgrades. We walked away with our boarding passes without looking at them. Later we look at passes and she changed my seat. Now we’re not sitting together after my husband bought our seats. We were assigned 9A and 9B, which we paid for. Now I’m in 9E. I went to the care point counter and the person who helped me said she couldn’t put me next to my husband, because he didn’t purchase 9A. I showed her our paperwork and the price we paid for the seats and her response was there’s nothing she could do. I then waited to speak with someone at the gate. The person I spoke with looked at our receipt and changed my seat to 9C. As we’re sitting waiting for boarding I needed to use the restroom, but the person who was there for security pulled the retractable belt barrier right in front of me and said I needed to hold it. I stood there for 5 minutes and then just sat back down…no one even walked by. I did Not like the way that I was treated and we will never fly Turkish Airlines again. If a trip we’re taking causes us to fly Turkish, I would have to think do I want to be treated this way again. There’s no reason to be treated this way Ever. Shame on Turkish!

Related info for your journey

  • What airport do you fly from for flights from Panama City to Rome?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl is the airport most travelers will use when flying to Rome from Panama City. Booking flights from Tocumen Intl (PTY) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 2 different airlines.

  • How long is the flight from Panama City to Rome?

    Airlines like Air Europa and Turkish Airlines fly from Panama City to Rome in about 13h 55m. The time it takes to get you to your destination can typically vary by up to 3h 40m. Panama City and Rome are separated by a distance of 5881 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Panama City to Rome round-trip?

    Flying on Air Europa is currently your cheapest option to Rome, with prices starting at $679. Another option worth looking into is Turkish Airlines, starting at $752 round trip. You may be able to fly from Panama City to Rome for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Rome that include hotel bookings?

    Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

  • Can I find deals for business class flights from Panama City to Rome?

    Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Rome?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Rome (average of $716). Flying from Panama City to Rome in July is currently the most expensive (average of $1,150). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Montepulciano
Santa Marinella

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Panama City to Rome

Panama City to Leonardo da Vinci/Fiumicino flights

Top 2 airlines flying from Panama City to Rome

AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$679Average$895FlexibilityNo cancel feeOn-time83%
Turkish AirlinesCheapest$752Average$882FlexibilityNo cancel feeOn-time77%

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