HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Rome

$254+ Cheap flights from Panama City (PTY) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — ROM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Rome with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Rome are usually found in March or May, booked 31 days in advance, depart on a Wednesday or Friday and return on a Monday

Cheap flight deals from Panama City to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$682
(Gotogate)

One-way from

$254
(Kiwi.com)

Popular in

January

Cheapest in

March

Average price

$850
From Panama City Tocumen Intl to Rome (ROM)
Search Deals
One-way flight from Panama City Tocumen Intl to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Panama City to Rome

Cheapest flights from Panama City to Rome
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Gotogate deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/299:45 pmPTY - FCO
1 stop18h 10mTurkish Airlines
Wed 11/56:45 amFCO - PTY
1 stop19h 05mTurkish Airlines
Deal found 9/17$682
This Air France deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1610:20 pmPTY - FCO
1 stop13h 05mAir France
Tue 11/259:55 amFCO - PTY
1 stop16h 15mAir France
Deal found 9/14$695
This FlightHub deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1811:05 amPTY - FCO
1 stop22h 50mCondor
Sun 9/288:20 amFCO - PTY
1 stop25h 20mCondor
Deal found 9/17$701
This Turkish Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:55 pmPTY - FCO
1 stop33h 35mTurkish Airlines
Sun 11/211:15 amFCO - PTY
1 stop38h 35mTurkish Airlines
Deal found 9/16$705
This KLM deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:45 pmPTY - FCO
1 stop18h 40mMultiple Airlines
Sat 11/224:20 pmFCO - PTY
1 stop33h 50mMultiple Airlines
Deal found 9/15$707
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/19:30 pmPTY - FCO
1 stop13h 55mAir Europa
Thu 12/116:25 pmFCO - PTY
1 stop31h 20mAir Europa
Deal found 9/15$714
This KLM deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:50 pmPTY - FCO
1 stop31h 35mMultiple Airlines
Thu 11/136:25 pmFCO - PTY
1 stop31h 45mMultiple Airlines
Deal found 9/16$716
This Turkish Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/39:45 pmPTY - FCO
1 stop34h 05mTurkish Airlines
Mon 11/176:45 amFCO - PTY
1 stop19h 05mTurkish Airlines
Deal found 9/16$727
This Turkish Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:55 pmPTY - FCO
1 stop37h 25mTurkish Airlines
Wed 10/296:45 amFCO - PTY
1 stop19h 05mTurkish Airlines
Deal found 9/16$731
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:45 pmPTY - FCO
1 stop17h 50mTurkish Airlines
Tue 11/257:35 pmFCO - PTY
1 stop30h 15mTurkish Airlines
Deal found 9/14$735

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Fly from

Panama City

Fly to

Rome

Route

Depart

Return

Price

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 11/6

6:45 pm-7:25 pm

1 stop18h 40m

Rome Fiumicino

Sat 11/22

4:20 pm-8:10 pm

1 stop33h 50m

$707

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 10/1

9:55 pm-6:20 pm

1 stop37h 25m

Rome Fiumicino

Wed 10/29

6:45 am-7:50 pm

1 stop19h 05m

$731

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 11/8

9:45 pm-9:55 pm

1 stop18h 10m

Rome Fiumicino

Sat 11/22

6:45 am-7:50 pm

1 stop19h 05m

$748

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 11/22

9:45 pm-9:50 am

1 stop30h 05m

Rome Fiumicino

Sat 11/29

6:45 am-7:50 pm

1 stop19h 05m

$748

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 10/27

9:45 pm-9:50 am

1 stop30h 05m

Rome Fiumicino

Mon 11/10

6:45 am-7:50 pm

1 stop19h 05m

$748

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 9/28

9:55 pm-9:20 am

1 stop28h 25m

Rome Fiumicino

Wed 10/29

6:45 am-7:50 pm

1 stop19h 05m

$752

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 10/1

9:55 pm-11:30 pm

1 stop18h 35m

Rome Fiumicino

Tue 10/7

3:30 pm-8:00 pm

1 stop35h 30m

$758

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 10/18

8:00 pm-2:30 pm

1 stop35h 30m

Rome Fiumicino

Mon 11/3

6:45 am-7:50 pm

1 stop19h 05m

$768

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 10/1

9:55 pm-6:20 pm

1 stop37h 25m

Rome Fiumicino

Thu 10/23

3:30 pm-6:20 pm

2 stops33h 50m

$774

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 9/28

9:55 pm-11:30 pm

1 stop18h 35m

Rome Fiumicino

Tue 10/28

7:35 pm-5:05 pm

2 stops27h 30m

$795

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 16 results
1
2

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

How far ahead should I book a flight from Panama City to Rome?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Rome. Price data was last updated on September 12, 2025.

The price you pay for your flight from Panama City to Rome may vary depending on when you book. For the best chance of a lower fare, look to book 31 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Rome?

Currently, January is the cheapest month in which you can book a flight from Panama City to Rome (average of $644). Flying from Panama City to Rome in June is currently the most expensive (average of $1,130). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to ROM?

Find hourly flight availability from Panama City to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

One of the essential ways to save on airfare from Panama City to Rome is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the morning could potentially save you up to 4% on airfare.

How much does it cost to fly round-trip from Panama City to Rome?

What’s the top layover airport for flights from Panama City to Rome?

Share of 1-stop round-trip flights from Panama City to Rome chosen by Cheapflights users in the past 12 months, using the same layover each way.

Amsterdam (AMS) – chosen by Cheapflights users on 63% of 1-stop itineraries from Panama City to Rome on Cheapflights.

What’s the cheapest layover airport for flights from Panama City to Rome?

Average round-trip fare for 1-stop flights from Panama City to Rome, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Amsterdam (AMS) is the most affordable 1-stop option, with an average round-trip price of $1,415.

What’s the fastest layover option from Panama City to Rome?

Shortest average travel time for 1-stop one-way flights from Panama City to Rome, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Madrid (MAD) have the shortest average one-way travel time for 1-stop routes: 14h 50m.

Which airport typically offers the quickest layover for flights from Panama City to Rome?

Average layover duration for 1-stop one-way flights from Panama City to Rome, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Madrid (MAD) offer the fastest connection on this route, with an average layover time of 2h 13m.

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Air France, United Airlines, and Turkish Airlines from Panama City to Rome. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,468 reviews

Comfort

7.4

Boarding

7.4

Food

7.0

Crew

8.2

Entertainment

7.0

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Air France
7.4
Good
1,468 reviews
Air France
7.4
Good
1,468 reviews

Comfort

7.4

Boarding

7.4

Food

7.0

Crew

8.2

Entertainment

7.0

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
United Airlines
7.4
Good
8,926 reviews
Air France
7.4
Good
1,468 reviews

Comfort

7.4

Boarding

7.4

Food

7.0

Crew

8.2

Entertainment

7.0

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Turkish Airlines
7.3
Good
3,965 reviews
Air France
7.4
Good
1,468 reviews

Comfort

7.4

Boarding

7.4

Food

7.0

Crew

8.2

Entertainment

7.0

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Air Europa
7.0
Good
557 reviews
Air France
7.4
Good
1,468 reviews

Comfort

7.4

Boarding

7.4

Food

7.0

Crew

8.2

Entertainment

7.0

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Iberia
7.0
Good
2,925 reviews
Air France
7.4
Good
1,468 reviews

Comfort

7.4

Boarding

7.4

Food

7.0

Crew

8.2

Entertainment

7.0

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Rome?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl is the airport most travelers will use when flying to Rome from Panama City. Booking flights from Tocumen Intl (PTY) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 4 different airlines.

  • How long is the flight from Panama City to Rome?

    Airlines like Turkish Airlines fly from Panama City to Rome in about 37h 25m. The time it takes to get you to your destination can typically vary by up to . Panama City and Rome are separated by a distance of 5881 mi.

  • What are the cheapest airlines flying from Panama City to Rome round-trip?

    Flying on Turkish Airlines is currently your cheapest option to Rome, with prices starting at $690. Additional round-trip tickets that might be worth considering are offered by Air Europa and Iberia, with the lowest prices starting at $746 and $747, respectively. You may be able to fly from Panama City to Rome for 20% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Rome that include hotel bookings?

    Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

  • Can I find deals for business class flights from Panama City to Rome?

    Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Rome?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Rome (average of $644). Flying from Panama City to Rome in June is currently the most expensive (average of $1,130). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Gaeta
Montepulciano
Santa Marinella

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Rome

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Leonardo da Vinci/Fiumicino flights

Top 4 airlines flying from Panama City to Rome

Discover the top 4 airlines that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$690Average$788FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$746Average$992FlexibilityNo cancel feeOn-time83%
IberiaCheapest$747Average$886FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$818Average$972FlexibilityNo cancel feeOn-time77%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.