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$784+ Cheap flights from Panama City (PTY) to Rome (ROM)

PTY — ROM
Nov 4 — Nov 111
Wed 11/4
Wed 11/11
1 adult, Economy
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Cheap flight deals from Panama City to Rome

Cheapest flights from Panama City to Rome

Mon 11/910:00 pm -
1 stop17h 55m
Mon 11/167:45 pm -
2 stops27h 25m
Deal found 10/4$858
Mon 11/910:00 pm -
1 stop29h 45m
Mon 11/237:45 pm -
2 stops27h 25m
Deal found 10/4$861
Wed 11/119:30 pm -
1 stop13h 55m
Mon 11/233:55 pm -
1 stop33h 50m
Deal found 10/5$872
Mon 11/99:30 pm -
1 stop13h 55m
Mon 11/233:55 pm -
1 stop33h 50m
Deal found 10/5$874
Thu 10/296:45 pm -
1 stop22h 30m
Tue 11/106:00 am -
2 stops20h 20m
Deal found 10/2$877
Wed 11/1110:00 pm -
1 stop17h 55m
Mon 11/236:55 am -
1 stop19h 10m
Deal found 10/1$880
Fri 11/139:30 pm -
1 stop35h 35m
Tue 11/173:55 pm -
1 stop33h 50m
Deal found 10/5$881
Mon 11/1610:00 pm -
1 stop38h 25m
Mon 11/236:55 am -
1 stop19h 10m
Deal found 10/2$890
Tue 11/176:45 pm -
1 stop18h 45m
Wed 12/26:00 am -
2 stops20h 35m
Deal found 10/4$901

Find flight deals from Panama City to Rome

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$858
(Turkish Airlines)

One-way from

$784
(Turkish Airlines)

Popular in

July

Cheapest in

April

Average price

$928
Provider with most accurate pricing for Panama City Tocumen Intl-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Rome (ROM) flights.
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From Panama City Tocumen Intl to Rome (ROM)
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One-way flight from Panama City Tocumen Intl to Rome (ROM)
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Highest demand for flights based on searches. 11% potential increase in price ($124 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in October 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

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Route

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Price

Cheapest round-trip
Quickest round-trip

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Sun 12/13

6:50 pm-9:55 pm

1 stop21h 05m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$784

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Sun 12/13

4:10 pm-1:25 pm

2 stops39h 15m

Rome Fiumicino

Wed 12/31

12:00 am-6:00 pm

Nonstop0h 00m

$826

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Wed 11/11

10:00 pm-9:55 pm

1 stop17h 55m

Rome Fiumicino

Mon 11/23

6:55 am-8:05 pm

1 stop19h 10m

$880

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Fri 11/13

10:00 pm-6:15 pm

1 stop38h 15m

Rome Fiumicino

Thu 11/26

2:50 pm-8:05 pm

1 stop35h 15m

$929

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Mon 11/9

10:00 pm-9:45 am

1 stop29h 45m

Rome Fiumicino

Mon 11/16

6:55 am-5:10 pm

2 stops40h 15m

$942

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Fri 11/13

10:00 am-10:55 am

1 stop18h 55m

Rome Fiumicino

Thu 11/26

1:55 pm-7:38 pm

2 stops35h 43m

$954

Panama CityRome

PTY Panama City Tocumen Intl - FCO Rome Fiumicino

PTYFCO

Panama City Tocumen Intl

Wed 11/11

10:00 am-7:55 am

1 stop15h 55m

Rome Fiumicino

Mon 11/23

1:55 pm-2:45 pm

2 stops30h 50m

$954

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/5

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Panama City-Rome flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Rome flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Rome flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

What is the cheapest month to book a flight from Panama City to Rome?

Currently, April is the cheapest month in which you can book a flight from Panama City to Rome (average of $752). Flying from Panama City to Rome in July is currently the most expensive (average of $1,136). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Rome?

Airfare is typical for this route at the moment.
Panama City to Rome flights typically cost between $858 and $1,071 in February.
The cheapest round-trip price found within the last 5 days was $858 on Turkish Airlines (Feb 1-Feb 17).

How far ahead should I book a flight from Panama City to Rome?

The price you pay for your flight from Panama City to Rome may vary depending on when you book. For the best chance of a lower fare, look to book 14 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Rome

Read reviews from past customers who have flown Turkish Airlines and Air Europa from Panama City to Rome. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.4
Good
4,455 reviews

Boarding

7.3

Food

7.5

Comfort

7.3

Crew

7.8

Entertainment

7.5

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2026

SEA - IST

I was in business class on this airplane for a 12 hour flight from Seattle to Istanbul. It was about the smoothest in the most luxurious flight. I think I have ever been on. The staff were excellent and extremely patient which I really appreciate it. Given the opportunity, I will certainly choose Turkish Airlines in the future. Job well done, hope to see you again in the future
Turkish Airlines
7.4
Good
4,455 reviews
Turkish Airlines
7.4
Good
4,455 reviews

Boarding

7.3

Food

7.5

Comfort

7.3

Crew

7.8

Entertainment

7.5

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2026

SEA - IST

I was in business class on this airplane for a 12 hour flight from Seattle to Istanbul. It was about the smoothest in the most luxurious flight. I think I have ever been on. The staff were excellent and extremely patient which I really appreciate it. Given the opportunity, I will certainly choose Turkish Airlines in the future. Job well done, hope to see you again in the future
Air Europa
6.9
Okay
641 reviews
Turkish Airlines
7.4
Good
4,455 reviews

Boarding

7.3

Food

7.5

Comfort

7.3

Crew

7.8

Entertainment

7.5

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2026

SEA - IST

I was in business class on this airplane for a 12 hour flight from Seattle to Istanbul. It was about the smoothest in the most luxurious flight. I think I have ever been on. The staff were excellent and extremely patient which I really appreciate it. Given the opportunity, I will certainly choose Turkish Airlines in the future. Job well done, hope to see you again in the future

Related info for your journey

  • What airport do you fly from for flights from Panama City to Rome?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl is the airport most travelers will use when flying to Rome from Panama City. Booking flights from Tocumen Intl (PTY) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 2 different airlines.

  • How long is the flight from Panama City to Rome?

    Airlines like Turkish Airlines fly from Panama City to Rome in about 17h 55m. The time it takes to get you to your destination can typically vary by up to . Panama City and Rome are separated by a distance of 5881 mi.

  • What are the cheapest airlines flying from Panama City to Rome round-trip?

    Flying on Turkish Airlines is currently your cheapest option to Rome, with prices starting at $752. Another option worth looking into is Air Europa, starting at $764 round trip. You may be able to fly from Panama City to Rome for 19% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Rome that include hotel bookings?

    Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

  • Can I find deals for business class flights from Panama City to Rome?

    Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Rome?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Rome (average of $752). Flying from Panama City to Rome in July is currently the most expensive (average of $1,136). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Montepulciano
Santa Marinella

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Alternative routes for Panama City to Rome

Panama City to Leonardo da Vinci/Fiumicino flights

Top 2 airlines flying from Panama City to Rome

AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$752Average$882FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$764Average$1,042FlexibilityNo cancel feeOn-time83%

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