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$505+ Cheap flights from Panama City (PTY) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — ROM
Aug 7 — Aug 141
Fri 8/7
Fri 8/14
1 adult, Economy
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Cheap flight deals from Panama City to Rome

Cheapest flights from Panama City to Rome
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.

This Air France deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm
PTY
-
FCO
1 stop18h 20m
Air France
Wed 10/286:00 am
FCO
-
PTY
1 stop20h 20m
Air France
Deal found 7/3$770
This KLM deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm
PTY
-
FCO
1 stop18h 20m
Multiple Airlines
Wed 10/286:10 am
FCO
-
PTY
2 stops20h 10m
Multiple Airlines
Deal found 7/3$801
This Air France deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm
PTY
-
FCO
1 stop28h 00m
Multiple Airlines
Tue 10/136:30 am
FCO
-
PTY
1 stop17h 20m
Multiple Airlines
Deal found 7/6$823
This KLM deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm
PTY
-
FCO
2 stops17h 50m
KLM
Wed 10/286:10 am
FCO
-
PTY
2 stops20h 10m
KLM
Deal found 7/3$833
This KLM deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:23 pm
PTY
-
FCO
2 stops20h 07m
Multiple Airlines
Wed 9/166:30 am
FCO
-
PTY
1 stop17h 20m
Multiple Airlines
Deal found 7/5$837
This Turkish Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:45 pm
PTY
-
FCO
1 stop30h 05m
Turkish Airlines
Mon 11/236:40 am
FCO
-
PTY
1 stop19h 25m
Turkish Airlines
Deal found 7/6$855
This Turkish Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:45 pm
PTY
-
FCO
1 stop18h 10m
Turkish Airlines
Thu 11/1211:15 am
FCO
-
PTY
1 stop38h 50m
Turkish Airlines
Deal found 7/6$856
This KLM deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm
PTY
-
FCO
2 stops17h 50m
KLM
Tue 10/136:30 am
FCO
-
PTY
1 stop17h 20m
KLM
Deal found 7/6$858

Find flight deals from Panama City to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$770
(Air France)

One-way from

$505
(Mytrip)

Popular in

July

Cheapest in

April

Average price

$1,106
Provider with most accurate pricing for Panama City Tocumen Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Rome (ROM) flights.
Search Deals
From Panama City Tocumen Intl to Rome (ROM)
Search Deals
One-way flight from Panama City Tocumen Intl to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 10/1

9:55 pm-10:45 pm

2 stops17h 50m

Rome Fiumicino

Wed 10/28

6:10 am-8:20 pm

2 stops20h 10m

$833

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 11/9

6:50 pm-6:20 pm

1 stop17h 30m

Rome Fiumicino

Mon 11/23

6:40 am-8:05 pm

1 stop19h 25m

$856
Quickest round-trip

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 10/1

9:55 pm-10:45 pm

2 stops17h 50m

Rome Fiumicino

Tue 10/13

6:30 am-4:50 pm

1 stop17h 20m

$858

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 9/12

2:23 pm-5:30 pm

2 stops20h 07m

Rome Fiumicino

Wed 9/16

8:10 pm-4:50 pm

2 stops27h 40m

$900

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 10/1

9:55 pm-10:45 pm

2 stops17h 50m

Rome Fiumicino

Tue 10/13

6:05 am-4:50 pm

2 stops17h 45m

$938

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 10/29

7:55 am-8:30 am

2 stops42h 35m

Rome Fiumicino

Wed 11/11

12:55 pm-8:02 pm

1 stop37h 07m

$944

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 11/1

10:00 am-10:55 am

1 stop18h 55m

Rome Fiumicino

Wed 11/11

1:15 pm-8:02 pm

2 stops36h 47m

$952

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 11/9

10:00 am-7:55 am

1 stop15h 55m

Rome Fiumicino

Mon 11/23

11:15 am-8:02 pm

2 stops38h 47m

$957
Cheapest one-way

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 8/19

10:20 pm-11:35 pm

1 stop18h 15m

$703

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Fri 8/21

10:20 pm-6:25 pm

1 stop37h 05m

$704

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/6

Showing 1-10 of 13 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Panama City-Rome flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Rome flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Rome flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

What is the cheapest month to book a flight from Panama City to Rome?

Currently, September is the cheapest month in which you can book a flight from Panama City to Rome (average of $312). Flying from Panama City to Rome in June is currently the most expensive (average of $819). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Rome?

How far ahead should I book a flight from Panama City to Rome?

The price you pay for your flight from Panama City to Rome may vary depending on when you book. For the best chance of a lower fare, look to book 40 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated July 8, 2026.
Read reviews from past customers who have flown Turkish Airlines and Air Europa from Panama City to Rome. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.4
Good
4,440 reviews

Comfort

7.3

Crew

7.8

Boarding

7.3

Food

7.5

Overall

7.4

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Michael,Nov 2024

IST - DTW

We arrived early and checked in. The lady at the counter was very rude to us, we believe it’s because we are a mixed race couple. I asked if we could upgrade our seats and she immediately said no upgrades. We walked away with our boarding passes without looking at them. Later we look at passes and she changed my seat. Now we’re not sitting together after my husband bought our seats. We were assigned 9A and 9B, which we paid for. Now I’m in 9E. I went to the care point counter and the person who helped me said she couldn’t put me next to my husband, because he didn’t purchase 9A. I showed her our paperwork and the price we paid for the seats and her response was there’s nothing she could do. I then waited to speak with someone at the gate. The person I spoke with looked at our receipt and changed my seat to 9C. As we’re sitting waiting for boarding I needed to use the restroom, but the person who was there for security pulled the retractable belt barrier right in front of me and said I needed to hold it. I stood there for 5 minutes and then just sat back down…no one even walked by. I did Not like the way that I was treated and we will never fly Turkish Airlines again. If a trip we’re taking causes us to fly Turkish, I would have to think do I want to be treated this way again. There’s no reason to be treated this way Ever. Shame on Turkish!
Turkish Airlines
7.4
Good
4,440 reviews
Turkish Airlines
7.4
Good
4,440 reviews

Comfort

7.3

Crew

7.8

Boarding

7.3

Food

7.5

Overall

7.4

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Michael,Nov 2024

IST - DTW

We arrived early and checked in. The lady at the counter was very rude to us, we believe it’s because we are a mixed race couple. I asked if we could upgrade our seats and she immediately said no upgrades. We walked away with our boarding passes without looking at them. Later we look at passes and she changed my seat. Now we’re not sitting together after my husband bought our seats. We were assigned 9A and 9B, which we paid for. Now I’m in 9E. I went to the care point counter and the person who helped me said she couldn’t put me next to my husband, because he didn’t purchase 9A. I showed her our paperwork and the price we paid for the seats and her response was there’s nothing she could do. I then waited to speak with someone at the gate. The person I spoke with looked at our receipt and changed my seat to 9C. As we’re sitting waiting for boarding I needed to use the restroom, but the person who was there for security pulled the retractable belt barrier right in front of me and said I needed to hold it. I stood there for 5 minutes and then just sat back down…no one even walked by. I did Not like the way that I was treated and we will never fly Turkish Airlines again. If a trip we’re taking causes us to fly Turkish, I would have to think do I want to be treated this way again. There’s no reason to be treated this way Ever. Shame on Turkish!
Air Europa
7.0
Good
624 reviews
Turkish Airlines
7.4
Good
4,440 reviews

Comfort

7.3

Crew

7.8

Boarding

7.3

Food

7.5

Overall

7.4

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Michael,Nov 2024

IST - DTW

We arrived early and checked in. The lady at the counter was very rude to us, we believe it’s because we are a mixed race couple. I asked if we could upgrade our seats and she immediately said no upgrades. We walked away with our boarding passes without looking at them. Later we look at passes and she changed my seat. Now we’re not sitting together after my husband bought our seats. We were assigned 9A and 9B, which we paid for. Now I’m in 9E. I went to the care point counter and the person who helped me said she couldn’t put me next to my husband, because he didn’t purchase 9A. I showed her our paperwork and the price we paid for the seats and her response was there’s nothing she could do. I then waited to speak with someone at the gate. The person I spoke with looked at our receipt and changed my seat to 9C. As we’re sitting waiting for boarding I needed to use the restroom, but the person who was there for security pulled the retractable belt barrier right in front of me and said I needed to hold it. I stood there for 5 minutes and then just sat back down…no one even walked by. I did Not like the way that I was treated and we will never fly Turkish Airlines again. If a trip we’re taking causes us to fly Turkish, I would have to think do I want to be treated this way again. There’s no reason to be treated this way Ever. Shame on Turkish!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Rome?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl is the airport most travelers will use when flying to Rome from Panama City. Booking flights from Tocumen Intl (PTY) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 2 different airlines.

  • How long is the flight from Panama City to Rome?

    Airlines like KLM and Turkish Airlines fly from Panama City to Rome in about 17h 30m. The time it takes to get you to your destination can typically vary by up to 20m. Panama City and Rome are separated by a distance of 5881 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Panama City to Rome round-trip?

    Flying on Air Europa is currently your cheapest option to Rome, with prices starting at $679. Another option worth looking into is Turkish Airlines, starting at $690 round trip. You may be able to fly from Panama City to Rome for 24% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Rome that include hotel bookings?

    Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

  • Can I find deals for business class flights from Panama City to Rome?

    Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Rome?

    Currently, September is the cheapest month in which you can book a flight from Panama City to Rome (average of $312). Flying from Panama City to Rome in June is currently the most expensive (average of $819). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Montepulciano
Santa Marinella

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Rome

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Leonardo da Vinci/Fiumicino flights

Top 2 airlines flying from Panama City to Rome

Discover the top 2 airlines that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$679Average$895FlexibilityNo cancel feeOn-time83%
Turkish AirlinesCheapest$690Average$854FlexibilityNo cancel feeOn-time77%

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