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$394+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This FlightHub deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:30 pm
STL
-
FCO
2 stops36h 20m
Scandinavian Airlines
Wed 9/2311:55 am
FCO
-
STL
2 stops42h 42m
Scandinavian Airlines
Deal found 3/29$727
This FlightHub deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:59 am
MCI
-
FCO
2 stops42h 06m
Scandinavian Airlines
Sun 9/69:30 am
FCO
-
MCI
2 stops21h 22m
Scandinavian Airlines
Deal found 3/31$757
This Scandinavian Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:30 pm
SGF
-
FCO
2 stops36h 35m
Scandinavian Airlines
Tue 12/811:55 am
FCO
-
SGF
2 stops41h 37m
Scandinavian Airlines
Deal found 3/28$761
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:55 pm
STL
-
FCO
2 stops16h 20m
Lufthansa
Wed 8/266:50 am
FCO
-
STL
1 stop13h 35m
Lufthansa
Deal found 3/31$773
This CheapOair deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:42 pm
STL
-
FCO
2 stops36h 23m
Scandinavian Airlines
Sat 9/56:55 pm
FCO
-
STL
2 stops35h 42m
Scandinavian Airlines
Deal found 3/28$778
This oojo deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:01 pm
STL
-
FCO
1 stop14h 19m
British Airways
Wed 8/1910:00 am
FCO
-
STL
1 stop20h 51m
British Airways
Deal found 3/27$785
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:45 pm
STL
-
FCO
2 stops15h 10m
American Airlines
Thu 11/1911:00 am
FCO
-
STL
1 stop15h 30m
American Airlines
Deal found 3/31$786
This Iberia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:14 am
STL
-
FCO
1 stop18h 51m
Iberia
Wed 8/191:10 pm
FCO
-
STL
1 stop17h 31m
Iberia
Deal found 3/31$790
This KAYAK deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:42 pm
STL
-
FCO
2 stops36h 23m
Scandinavian Airlines
Sun 9/69:30 am
FCO
-
STL
2 stops21h 07m
Scandinavian Airlines
Deal found 3/28$791
This Expedia deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:39 am
STL
-
FCO
1 stop16h 06m
Iberia
Fri 11/277:30 am
FCO
-
STL
2 stops18h 57m
Iberia
Deal found 3/29$810
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:13 am
MCI
-
FCO
1 stop16h 57m
Iberia
Tue 8/251:10 pm
FCO
-
MCI
1 stop16h 51m
Iberia
Deal found 3/27$814
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:37 pm
MCI
-
FCO
2 stops16h 38m
Lufthansa
Wed 12/169:45 am
FCO
-
MCI
2 stops22h 07m
Lufthansa
Deal found 3/31$819

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$757
(FlightHub)

One-way from

$394
(Cheapflightsfares)

Popular in

June

Cheapest in

February

Average price

$871
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($399 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($62 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Sun 8/16

8:00 am-7:55 am

1 stop16h 55m

Rome Fiumicino

Thu 8/20

7:10 am-8:30 pm

2 stops20h 20m

$842

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Mon 8/3

11:25 am-1:15 pm

2 stops18h 50m

Rome Fiumicino

Fri 8/21

8:00 am-5:34 pm

2 stops16h 34m

$853

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 5/13

1:05 pm-9:15 am

1 stop13h 10m

Rome Fiumicino

Wed 5/20

6:50 am-8:25 pm

2 stops20h 35m

$971

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sat 5/9

4:15 pm-12:20 pm

1 stop37h 05m

Rome Fiumicino

Tue 5/19

11:30 am-8:25 pm

1 stop15h 55m

$985

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 8/23

7:45 am-7:55 am

1 stop17h 10m

Rome Fiumicino

Sat 8/29

2:20 pm-2:17 pm

2 stops30h 57m

$995

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Mon 5/11

11:30 am-7:55 am

1 stop13h 25m

Rome Fiumicino

Mon 5/18

1:20 pm-8:49 pm

2 stops38h 29m

$1,000

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sat 4/25

5:12 pm-7:35 am

1 stop31h 23m

Rome Fiumicino

Wed 5/6

9:45 am-11:55 pm

1 stop21h 10m

$1,020

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Sun 9/6

3:30 pm-11:05 am

2 stops36h 35m

Rome Fiumicino

Sun 9/20

9:30 am-10:29 pm

2 stops19h 59m

$1,039

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Fri 5/15

8:00 am-10:00 pm

2 stops31h 00m

Rome Fiumicino

Fri 5/22

6:50 am-9:59 pm

2 stops22h 09m

$1,046

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Wed 4/29

9:00 am-12:20 pm

1 stop20h 20m

Rome Fiumicino

Wed 5/6

2:20 pm-2:26 pm

2 stops31h 06m

$1,066

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in June is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Rome?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 16h 55m. Air Canada provides one of the quickest options available for as low as $842. There are 5122 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in June is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Missouri to Rome

Discover the top 8 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$1,166FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$506Average$993FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$907FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$514Average$1,011FlexibilityNo cancel feeOn-time69%
DeltaCheapest$555Average$906FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$665Average$934FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$705Average$1,282FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$724Average$1,200FlexibilityNo cancel feeOn-time67%

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