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$349+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
May 17 — May 241
Sun 5/17
Sun 5/24
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.

This oojo deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:22 am
STL
-
FCO
1 stop16h 58m
British Airways
Wed 8/191:30 pm
FCO
-
STL
1 stop16h 10m
British Airways
Deal found 4/15$786
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:17 pm
COU
-
FCO
2 stops17h 48m
American Airlines
Tue 8/251:30 pm
FCO
-
COU
1 stop15h 36m
American Airlines
Deal found 4/12$787
This FlightHub deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:59 am
MCI
-
FCO
2 stops42h 06m
Scandinavian Airlines
Sun 9/69:30 am
FCO
-
MCI
2 stops21h 22m
Scandinavian Airlines
Deal found 4/12$788
This Expedia deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:14 am
STL
-
FCO
1 stop18h 51m
Iberia
Wed 8/198:25 pm
FCO
-
STL
2 stops34h 16m
Iberia
Deal found 4/14$806
This oojo deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:00 pm
STL
-
FCO
1 stop30h 10m
British Airways
Tue 8/189:05 pm
FCO
-
STL
1 stop29h 25m
British Airways
Deal found 4/15$807
This British Airways deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:17 pm
STL
-
FCO
2 stops15h 03m
British Airways
Tue 12/157:25 am
FCO
-
STL
2 stops22h 00m
British Airways
Deal found 4/14$808
This FlightHub deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:59 am
MCI
-
FCO
2 stops42h 06m
Scandinavian Airlines
Sat 8/227:25 pm
FCO
-
MCI
2 stops34h 38m
Scandinavian Airlines
Deal found 4/16$809
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:50 pm
STL
-
FCO
2 stops17h 05m
American Airlines
Tue 12/151:00 pm
FCO
-
STL
1 stop28h 17m
American Airlines
Deal found 4/14$810
This deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:35 pm
STL
-
FCO
1 stop15h 30m
British Airways
Tue 8/2511:05 am
FCO
-
STL
1 stop15h 25m
British Airways
Deal found 4/15$811
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:37 pm
STL
-
FCO
1 stop12h 33m
American Airlines
Wed 8/191:30 pm
FCO
-
STL
2 stops17h 21m
American Airlines
Deal found 4/15$813
This deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:10 pm
STL
-
FCO
1 stop14h 05m
Air Canada
Thu 8/2711:30 am
FCO
-
STL
1 stop14h 12m
Air Canada
Deal found 4/15$817
This Cheapflightsfares deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:18 pm
STL
-
FCO
2 stops13h 42m
Lufthansa
Thu 8/2710:00 am
FCO
-
STL
2 stops20h 00m
Lufthansa
Deal found 4/15$819

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated April 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$786
(oojo)

One-way from

$349
(oojo)

Popular in

June

Cheapest in

February

Average price

$867
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 31% potential increase in price ($423 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($68 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Tue 8/18

7:17 pm-8:05 pm

2 stops17h 48m

Rome Fiumicino

Tue 8/25

1:30 pm-10:06 pm

1 stop15h 36m

$787

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Sun 8/16

3:18 pm-2:35 pm

2 stops16h 17m

Rome Fiumicino

Wed 8/26

10:00 am-5:17 pm

1 stop14h 17m

$863

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Tue 10/13

12:47 pm-12:05 pm

1 stop16h 18m

Rome Fiumicino

Tue 10/20

7:35 am-11:58 pm

2 stops23h 23m

$917

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Wed 10/7

6:01 am-9:10 am

1 stop20h 09m

Rome Fiumicino

Wed 10/21

7:35 am-6:06 pm

2 stops17h 31m

$928

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 8/23

6:00 am-12:20 pm

1 stop23h 20m

Rome Fiumicino

Sat 8/29

2:20 pm-2:17 pm

2 stops30h 57m

$996

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Thu 10/8

12:52 pm-2:20 pm

2 stops18h 28m

Rome Fiumicino

Thu 10/22

7:20 am-6:06 pm

2 stops17h 46m

$1,002

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Thu 10/8

12:00 pm-12:05 pm

1 stop17h 05m

Rome Fiumicino

Thu 10/22

11:10 am-10:35 pm

2 stops18h 25m

$1,004

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sun 9/6

6:42 am-12:05 pm

1 stop22h 23m

Rome Fiumicino

Sun 9/20

10:40 am-7:30 pm

1 stop15h 50m

$1,023
Quickest round-trip

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sun 5/10

1:05 pm-9:15 am

1 stop13h 10m

Rome Fiumicino

Sun 5/17

11:30 am-8:25 pm

1 stop15h 55m

$1,033

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sat 9/26

6:49 pm-9:15 am

2 stops31h 26m

Rome Fiumicino

Sun 10/4

6:50 am-3:38 pm

2 stops15h 48m

$1,049

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/12

Showing 1-10 of 55 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, August is the cheapest month in which you can book a flight from Missouri to Rome (average of $287). Flying from Missouri to Rome in June is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Rome?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 16h 17m. American Airlines provides one of the quickest options available for as low as $863. There are 5242 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $287. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Rome (average of $287). Flying from Missouri to Rome in June is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Missouri to Rome

Discover the top 8 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$1,183FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$500Average$993FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$907FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$514Average$989FlexibilityNo cancel feeOn-time69%
DeltaCheapest$555Average$936FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$564Average$1,200FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$665Average$1,001FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$705Average$1,282FlexibilityNo cancel feeOn-time77%

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