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$277+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$532
(lol.travel)

One-way from

$277
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$1,046
From Missouri to Rome (ROM)
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One-way flight from Missouri to Rome (ROM)
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Highest demand for flights based on searches. 24% potential increase in price ($360 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($44 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This lol.travel deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/203:23 pmSTL - FCO
2 stops14h 42mUnited Airlines
mié. 11/57:05 amFCO - STL
1 stop13h 50mUnited Airlines
Deal found 9/15$532
This Billigflug deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/203:23 pmSTL - FCO
2 stops14h 42mMultiple Airlines
mié. 11/57:05 amFCO - STL
1 stop13h 50mMultiple Airlines
Deal found 9/14$547
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/28:00 amMCI - FCO
1 stop16h 45mUnited Airlines
vie. 12/1212:45 pmFCO - MCI
2 stops35h 44mUnited Airlines
Deal found 9/15$552
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/294:50 pmSTL - FCO
1 stop13h 50mLufthansa
mié. 11/57:05 amFCO - STL
2 stops17h 34mLufthansa
Deal found 9/14$553
This United deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/105:24 pmSTL - FCO
1 stop31h 21mMultiple Airlines
vie. 11/211:15 pmFCO - STL
2 stops33h 14mMultiple Airlines
Deal found 9/14$560
This KAYAK deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/249:59 amMCI - FCO
2 stops18h 06mScandinavian Airlines
mié. 12/311:55 amFCO - MCI
2 stops41h 49mScandinavian Airlines
Deal found 9/13$560
This Air Canada deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/28:00 amMCI - FCO
3 stops20h 05mMultiple Airlines
vie. 12/1212:45 pmFCO - MCI
2 stops32h 36mMultiple Airlines
Deal found 9/15$563
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:32 pmMCI - FCO
2 stops31h 43mAir Canada
mié. 12/1712:45 pmFCO - MCI
2 stops27h 33mAir Canada
Deal found 9/14$566
This KLM deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/191:37 pmMCI - FCO
1 stop14h 28mKLM
mar. 11/412:40 pmFCO - MCI
1 stop17h 59mKLM
Deal found 9/13$567
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/203:59 pmSTL - FCO
1 stop12h 06mDelta
mié. 11/59:20 amFCO - STL
1 stop29h 53mDelta
Deal found 9/15$568
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:00 amSGF - FCO
2 stops20h 45mDelta
mar. 11/2512:40 pmFCO - SGF
1 stop33h 37mDelta
Deal found 9/15$568
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:30 amSTL - FCO
2 stops19h 25mUnited Airlines
vie. 11/217:05 amFCO - STL
1 stop13h 50mUnited Airlines
Deal found 9/14$569

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Missouri

Fly to

Rome

Route

Depart

Return

Price

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

mar. 12/2

6:00 am-7:45 am

1 stop18h 45m

Rome Fiumicino

vie. 12/12

12:45 pm-5:29 pm

2 stops35h 44m

$552

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

dom. 10/19

1:37 pm-11:05 am

1 stop14h 28m

Rome Fiumicino

mar. 11/4

12:40 pm-11:39 pm

1 stop17h 59m

$567

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

dom. 11/9

6:00 am-9:45 am

2 stops20h 45m

Rome Fiumicino

mar. 11/25

12:40 pm-3:17 pm

1 stop33h 37m

$568

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

mar. 12/2

6:00 am-9:00 am

1 stop20h 00m

Rome Fiumicino

vie. 12/12

1:00 pm-11:01 pm

1 stop17h 01m

$575

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mar. 3/10

6:45 am-7:45 am

1 stop19h 00m

Rome Fiumicino

mar. 3/17

10:30 am-9:10 pm

1 stop16h 40m

$575

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mar. 11/11

9:21 am-10:30 am

1 stop18h 09m

Rome Fiumicino

mar. 11/18

9:20 am-4:33 pm

1 stop14h 13m

$575

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mar. 11/11

6:43 pm-8:55 am

2 stops31h 12m

Rome Fiumicino

mar. 11/18

7:05 am-3:29 pm

2 stops39h 24m

$575

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

mié. 10/29

12:36 pm-6:55 am

1 stop12h 19m

Rome Fiumicino

mar. 11/11

12:40 pm-9:10 pm

1 stop15h 30m

$575

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

mar. 10/28

10:30 am-6:55 am

1 stop14h 25m

Rome Fiumicino

mar. 11/4

12:40 pm-9:08 pm

1 stop15h 28m

$575

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mié. 3/11

1:27 pm-2:00 pm

2 stops18h 33m

Rome Fiumicino

mar. 3/17

1:30 pm-3:29 pm

2 stops31h 59m

$595

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 54 results
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $644). Flying from Missouri to Rome in June is currently the most expensive (average of $1,133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ROM?

Find hourly flight availability from Missouri to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Rome as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 18h 09m. United Airlines provides one of the quickest options available for as low as $575. There are 5050 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is Iberia, with whom users have recently found tickets for as low as $448. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $644). Flying from Missouri to Rome in June is currently the most expensive (average of $1,133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Gaeta
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Rome

Discover the top 9 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest$536Average$1,215FlexibilityNo cancel feeOn-time77%
DeltaCheapest$554Average$906FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$559Average$1,082FlexibilityNo cancel feeOn-time69%
KLMCheapest$604Average$1,031FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$665Average$1,172FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$671Average$1,115FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$697Average$1,139FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$705Average$1,167FlexibilityNo cancel feeOn-time67%
Air FranceCheapest$744Average$1,295FlexibilityNo cancel feeOn-time77%

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