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$336+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
Apr 18 — Apr 251
Sat 4/18
Sat 4/25
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 19, 2026.

This FlightHub deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:59 am
MCI
-
FCO
2 stops42h 06m
Scandinavian Airlines
Sun 9/67:25 pm
FCO
-
MCI
2 stops33h 57m
Scandinavian Airlines
Deal found 3/15$647
This Expedia deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:42 pm
STL
-
FCO
2 stops36h 23m
Scandinavian Airlines
Wed 8/2611:55 am
FCO
-
STL
2 stops42h 42m
Scandinavian Airlines
Deal found 3/15$669
This oojo deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:01 pm
STL
-
FCO
1 stop14h 19m
British Airways
Wed 8/2610:00 am
FCO
-
STL
1 stop16h 14m
British Airways
Deal found 3/15$685
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:23 am
STL
-
FCO
1 stop18h 47m
American Airlines
Wed 8/2610:00 am
FCO
-
STL
1 stop16h 14m
American Airlines
Deal found 3/15$690
This oojo deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:37 pm
STL
-
FCO
1 stop12h 33m
British Airways
Tue 8/188:15 pm
FCO
-
STL
1 stop30h 15m
British Airways
Deal found 3/16$695
This Iberia deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:35 pm
STL
-
FCO
1 stop12h 20m
Multiple Airlines
Wed 8/191:10 pm
FCO
-
STL
1 stop16h 53m
Multiple Airlines
Deal found 3/16$700
This KAYAK deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:42 pm
STL
-
FCO
2 stops36h 23m
Scandinavian Airlines
Sun 9/69:30 am
FCO
-
STL
2 stops21h 07m
Scandinavian Airlines
Deal found 3/17$711
This oojo deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:39 am
STL
-
FCO
1 stop16h 06m
British Airways
Sat 12/51:00 pm
FCO
-
STL
1 stop14h 21m
British Airways
Deal found 3/15$735
This Cheapflightsfares deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:53 am
MCI
-
FCO
2 stops23h 27m
SWISS
Wed 8/198:15 pm
FCO
-
MCI
2 stops32h 25m
SWISS
Deal found 3/15$735
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:08 pm
STL
-
FCO
2 stops15h 42m
American Airlines
Sat 12/51:00 pm
FCO
-
STL
1 stop14h 21m
American Airlines
Deal found 3/15$736
This Expedia deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:17 pm
STL
-
FCO
2 stops15h 33m
British Airways
Sun 11/151:00 pm
FCO
-
STL
1 stop14h 55m
British Airways
Deal found 3/17$737
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:30 pm
MCI
-
FCO
1 stop12h 45m
United Airlines
Wed 8/192:20 pm
FCO
-
MCI
2 stops32h 59m
United Airlines
Deal found 3/15$744

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated March 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$647
(FlightHub)

One-way from

$336
(oojo)

Popular in

June

Cheapest in

February

Average price

$894
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($399 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($62 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 4/15

6:19 am-10:10 am

1 stop20h 51m

Rome Fiumicino

Thu 4/30

12:45 pm-11:36 pm

2 stops17h 51m

$870

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sat 4/25

5:41 pm-10:10 am

1 stop33h 29m

Rome Fiumicino

Wed 5/6

9:00 am-8:45 pm

1 stop18h 45m

$911

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Tue 4/14

3:21 pm-7:55 am

1 stop33h 34m

Rome Fiumicino

Tue 4/21

11:30 am-10:27 am

2 stops29h 57m

$912

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 8/23

5:45 pm-1:15 pm

1 stop12h 30m

Rome Fiumicino

Sat 8/29

6:50 am-5:34 pm

2 stops17h 44m

$913

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Fri 4/17

7:45 am-9:20 am

2 stops18h 35m

Rome Fiumicino

Sun 4/26

3:30 pm-9:13 pm

2 stops36h 43m

$934

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sat 5/9

4:30 pm-2:20 pm

2 stops14h 50m

Rome Fiumicino

Tue 5/19

6:50 am-4:41 pm

2 stops16h 51m

$956

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Fri 5/8

4:30 pm-2:35 pm

2 stops15h 05m

Rome Fiumicino

Fri 5/15

6:55 am-4:41 pm

2 stops16h 46m

$956

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Thu 4/30

4:28 pm-4:55 pm

2 stops17h 27m

Rome Fiumicino

Thu 5/7

7:20 am-9:29 pm

2 stops21h 09m

$957

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Mon 5/11

4:25 pm-2:25 pm

2 stops15h 00m

Rome Fiumicino

Wed 5/20

2:45 pm-11:21 pm

1 stop15h 36m

$960

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sat 4/11

5:45 pm-9:15 am

2 stops32h 30m

Rome Fiumicino

Sat 4/18

1:20 pm-2:25 pm

2 stops32h 05m

$985

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in June is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 20h 51m. Delta provides one of the quickest options available for as low as $870. There are 5050 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in June is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Rome

Discover the top 9 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$1,126FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$500Average$987FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$867FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$514Average$1,011FlexibilityNo cancel feeOn-time69%
DeltaCheapest$555Average$905FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$665Average$993FlexibilityNo cancel feeOn-time71%
IberiaCheapest$692Average$1,322FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$705Average$1,173FlexibilityNo cancel feeOn-time67%

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