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$349+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
may. 24 — may. 311
dom. 5/24
dom. 5/31
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 24, 2026.

This FlightHub deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/123:42 pm
STL
-
FCO
2 stops19h 53m
Scandinavian Airlines
vie. 9/187:25 pm
FCO
-
STL
2 stops32h 25m
Scandinavian Airlines
Deal found 4/20$779
This FlightHub deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/269:59 am
MCI
-
FCO
2 stops42h 06m
Scandinavian Airlines
vie. 9/119:40 am
FCO
-
MCI
2 stops20h 23m
Scandinavian Airlines
Deal found 4/21$779
This oojo deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/56:06 am
STL
-
FCO
1 stop20h 04m
British Airways
mié. 8/191:30 pm
FCO
-
STL
1 stop16h 10m
British Airways
Deal found 4/19$786
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/182:50 pm
STL
-
FCO
2 stops14h 35m
American Airlines
jue. 11/2611:00 am
FCO
-
STL
1 stop18h 29m
American Airlines
Deal found 4/20$788
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/219:47 am
STL
-
FCO
1 stop16h 23m
Iberia
vie. 11/611:00 am
FCO
-
STL
1 stop30h 37m
Iberia
Deal found 4/20$797
This FlightHub deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2112:10 pm
STL
-
FCO
1 stop14h 05m
Air Canada
vie. 11/612:15 pm
FCO
-
STL
2 stops38h 10m
Air Canada
Deal found 4/20$804
This FlightHub deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/259:59 am
MCI
-
FCO
2 stops42h 06m
Scandinavian Airlines
dom. 9/69:30 am
FCO
-
MCI
2 stops21h 22m
Scandinavian Airlines
Deal found 4/19$809
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/56:06 am
STL
-
FCO
1 stop20h 04m
American Airlines
mié. 8/191:30 pm
FCO
-
STL
2 stops17h 21m
American Airlines
Deal found 4/20$813
This Justfly.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/14:15 pm
STL
-
FCO
2 stops34h 45m
Air Canada
mar. 12/1512:15 pm
FCO
-
STL
2 stops31h 05m
Air Canada
Deal found 4/20$817
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/110:23 am
STL
-
FCO
1 stop14h 22m
United Airlines
mar. 12/151:30 pm
FCO
-
STL
2 stops33h 00m
United Airlines
Deal found 4/20$822
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/75:00 am
COU
-
FCO
1 stop19h 45m
United Airlines
mié. 12/99:45 am
FCO
-
COU
2 stops18h 35m
United Airlines
Deal found 4/20$854
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/151:08 pm
MCI
-
FCO
1 stop11h 37m
United Airlines
vie. 12/47:05 am
FCO
-
MCI
2 stops21h 29m
United Airlines
Deal found 4/20$864

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated abril 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$779
(FlightHub)

One-way from

$349
(Cheapflightsfares)

Popular in

June

Cheapest in

February

Average price

$867
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 31% potential increase in price ($421 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($67 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 24, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

mar. 9/22

2:41 pm-3:10 pm

2 stops17h 29m

Rome Fiumicino

mié. 9/30

10:00 am-10:35 pm

2 stops19h 35m

$926

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

jue. 10/15

8:00 am-10:00 am

2 stops19h 00m

Rome Fiumicino

vie. 10/16

3:20 pm-10:33 am

2 stops26h 13m

$950

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mié. 9/30

9:35 pm-4:55 pm

1 stop12h 20m

Rome Fiumicino

mar. 10/6

11:55 am-7:30 pm

1 stop14h 35m

$951

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

jue. 10/8

2:42 pm-2:20 pm

2 stops16h 38m

Rome Fiumicino

jue. 10/22

11:05 am-6:06 pm

1 stop14h 01m

$982

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

dom. 8/23

9:10 am-12:20 pm

1 stop20h 10m

Rome Fiumicino

sáb. 8/29

2:20 pm-2:17 pm

2 stops30h 57m

$996

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

mar. 7/21

7:45 am-9:15 am

2 stops18h 30m

Rome Fiumicino

jue. 8/20

7:10 am-12:56 am

2 stops24h 46m

$998

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

mié. 9/30

8:55 am-10:20 am

1 stop18h 25m

Rome Fiumicino

dom. 10/4

9:45 am-8:37 am

1 stop29h 52m

$1,051

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

dom. 9/6

5:47 pm-3:50 pm

2 stops15h 03m

Rome Fiumicino

dom. 9/20

9:00 pm-8:25 pm

2 stops30h 25m

$1,075

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

mié. 7/15

6:55 pm-7:55 am

1 stop30h 00m

Rome Fiumicino

jue. 8/20

2:20 pm-4:24 pm

1 stop33h 04m

$1,087

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

sáb. 5/9

4:15 pm-12:20 pm

1 stop37h 05m

Rome Fiumicino

mar. 5/19

11:30 am-8:25 pm

1 stop15h 55m

$1,091

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 58 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

How far ahead should I book a flight from Missouri to Rome?

The best time to book flights from Missouri to Rome is 5 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Missouri to Rome?

Currently, August is the cheapest month in which you can book a flight from Missouri to Rome (average of $287). Flying from Missouri to Rome in June is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Rome?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 12h 20m. American Airlines provides one of the quickest options available for as low as $951. There are 5050 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $287. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Rome (average of $287). Flying from Missouri to Rome in June is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Missouri to Rome

Discover the top 8 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$1,217FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$500Average$987FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$907FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$514Average$977FlexibilityNo cancel feeOn-time69%
DeltaCheapest$555Average$949FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$564Average$1,225FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$665Average$1,003FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$705Average$1,295FlexibilityNo cancel feeOn-time77%

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