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$320+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
Mar 18 — Mar 251
Wed 3/18
Wed 3/25
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 16, 2026.

This oojo deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:53 pm
STL
-
FCO
1 stop32h 57m
British Airways
Wed 4/2210:00 am
FCO
-
STL
1 stop20h 46m
British Airways
Deal found 2/13$511
This Expedia deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:03 pm
STL
-
FCO
2 stops34h 52m
Iberia
Wed 4/2210:00 am
FCO
-
STL
1 stop19h 17m
Iberia
Deal found 2/14$517
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:00 am
MCI
-
FCO
2 stops18h 30m
United Airlines
Tue 3/3111:30 am
FCO
-
MCI
2 stops39h 18m
United Airlines
Deal found 2/14$592
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:41 am
STL
-
FCO
1 stop17h 04m
Delta
Wed 4/19:00 am
FCO
-
STL
1 stop15h 05m
Delta
Deal found 2/13$596
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:05 am
MCI
-
FCO
1 stop17h 50m
Delta
Tue 3/2410:05 am
FCO
-
MCI
1 stop28h 48m
Delta
Deal found 2/15$597
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:12 am
STL
-
FCO
2 stops15h 28m
Delta
Tue 3/2410:05 am
FCO
-
STL
2 stops19h 53m
Delta
Deal found 2/14$598
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:15 am
COU
-
FCO
1 stop14h 30m
United Airlines
Tue 3/2411:00 am
FCO
-
COU
2 stops29h 33m
United Airlines
Deal found 2/15$598
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:15 pm
STL
-
FCO
2 stops31h 05m
United Airlines
Wed 4/2212:25 pm
FCO
-
STL
2 stops39h 43m
United Airlines
Deal found 2/15$601
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:15 am
MCI
-
FCO
2 stops19h 40m
United Airlines
Tue 3/2410:30 am
FCO
-
MCI
2 stops31h 49m
United Airlines
Deal found 2/14$601
This KLM deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:35 am
MCI
-
FCO
1 stop14h 30m
KLM
Tue 3/319:45 am
FCO
-
MCI
1 stop14h 49m
KLM
Deal found 2/14$607
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:35 am
MCI
-
FCO
1 stop14h 30m
Delta
Tue 3/316:30 am
FCO
-
MCI
2 stops19h 49m
Delta
Deal found 2/14$609
This CheapOair deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:15 pm
STL
-
FCO
2 stops31h 05m
Air Canada
Wed 4/2212:25 pm
FCO
-
STL
1 stop33h 59m
Air Canada
Deal found 2/15$610

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated February 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$511
(oojo)

One-way from

$320
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$540
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($386 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($58 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Missouri

Fly to

Rome

Route

Depart

Return

Price

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Mon 3/23

8:00 am-8:30 am

2 stops18h 30m

Rome Fiumicino

Tue 3/31

11:30 am-7:48 pm

2 stops39h 18m

$592

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Mon 3/16

9:41 am-8:45 am

1 stop17h 04m

Rome Fiumicino

Wed 4/1

9:00 am-5:05 pm

1 stop15h 05m

$596

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Wed 3/18

6:41 pm-9:30 am

1 stop32h 49m

Rome Fiumicino

Tue 3/24

10:05 am-8:53 am

1 stop28h 48m

$597

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Wed 3/18

11:15 am-7:45 am

1 stop14h 30m

Rome Fiumicino

Tue 3/24

11:00 am-10:33 am

2 stops29h 33m

$598

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 3/18

10:12 am-7:40 am

2 stops15h 28m

Rome Fiumicino

Tue 3/24

10:05 am-11:58 pm

2 stops19h 53m

$598

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 4/14

8:15 pm-10:20 am

2 stops31h 05m

Rome Fiumicino

Wed 4/22

12:25 pm-9:08 pm

2 stops39h 43m

$601

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Mon 3/23

9:35 am-6:05 am

1 stop14h 30m

Rome Fiumicino

Tue 3/31

9:45 am-5:34 pm

1 stop14h 49m

$607

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Wed 3/18

6:15 am-7:55 am

2 stops19h 40m

Rome Fiumicino

Tue 3/24

10:30 am-12:19 pm

2 stops31h 49m

$615

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sat 4/25

3:15 pm-7:55 am

1 stop33h 40m

Rome Fiumicino

Tue 5/5

11:30 am-10:33 am

2 stops30h 03m

$633

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Tue 4/14

6:00 am-12:20 pm

1 stop23h 20m

Rome Fiumicino

Tue 4/21

11:30 am-9:59 pm

2 stops41h 29m

$633

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/13

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in June is currently the most expensive (average of $1,007). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 14h 30m. United Airlines provides one of the quickest options available for as low as $607. There are 5199 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $428. However, be on the lookout for offers from Iberia and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in June is currently the most expensive (average of $1,007). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Rome

Discover the top 9 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$1,014FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$506Average$987FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$943FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$514Average$1,004FlexibilityNo cancel feeOn-time69%
DeltaCheapest$566Average$891FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$665Average$1,089FlexibilityNo cancel feeOn-time71%
IberiaCheapest$692Average$1,323FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$705Average$1,170FlexibilityNo cancel feeOn-time67%

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