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$241+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
Nov 16 — Nov 231
Sun 11/16
Sun 11/23
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated October 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$518
(Kiwi.com)

One-way from

$241
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$906
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
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From Missouri to Rome (ROM)
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One-way flight from Missouri to Rome (ROM)
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Highest demand for flights based on searches. 25% potential increase in price ($358 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($52 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:35 amSTL - FCO
2 stops18h 05mLufthansa
Tue 11/256:45 pmFCO - STL
1 stop26h 10mLufthansa
Deal found 10/16$518
This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/174:05 pmSTL - FCO
1 stop12h 00mMultiple Airlines
Wed 11/267:05 amFCO - STL
1 stop13h 50mMultiple Airlines
Deal found 10/16$525
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:25 amSTL - FCO
1 stop17h 05mUnited Airlines
Wed 11/191:15 pmFCO - STL
2 stops32h 09mUnited Airlines
Deal found 10/16$532
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/28:00 amMCI - FCO
1 stop16h 45mUnited Airlines
Fri 12/121:10 pmFCO - MCI
2 stops35h 19mUnited Airlines
Deal found 10/15$532
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/308:00 amCOU - FCO
1 stop16h 45mUnited Airlines
Sun 12/71:10 pmFCO - COU
2 stops39h 12mUnited Airlines
Deal found 10/16$532
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:05 pmSTL - FCO
1 stop11h 50mAir Canada
Fri 12/121:10 pmFCO - STL
2 stops33h 30mAir Canada
Deal found 10/16$534
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/21:00 pmSTL - FCO
1 stop11h 45mUnited Airlines
Tue 12/161:10 pmFCO - STL
2 stops30h 05mUnited Airlines
Deal found 10/16$539
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:00 amCOU - FCO
1 stop16h 45mUnited Airlines
Tue 12/91:10 pmFCO - COU
2 stops35h 30mUnited Airlines
Deal found 10/14$539
This CheapOair deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:05 pmSTL - FCO
2 stops34h 20mAir Canada
Tue 12/91:10 pmFCO - STL
2 stops33h 30mAir Canada
Deal found 10/15$541
This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/184:05 pmSTL - FCO
1 stop11h 50mMultiple Airlines
Tue 11/256:45 pmFCO - STL
1 stop26h 10mMultiple Airlines
Deal found 10/16$545
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:00 amSGF - FCO
1 stop16h 45mUnited Airlines
Wed 11/267:05 amFCO - SGF
2 stops21h 41mUnited Airlines
Deal found 10/16$546
This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/134:05 pmSTL - FCO
2 stops14h 55mMultiple Airlines
Thu 11/209:40 amFCO - STL
1 stop35h 15mMultiple Airlines
Deal found 10/16$547

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 17, 2025.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Missouri

Fly to

Rome

Route

Depart

Return

Price

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 12/2

1:00 pm-7:45 am

1 stop11h 45m

Rome Fiumicino

Fri 12/12

1:10 pm-10:45 pm

2 stops40h 35m

$532

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Fri 11/14

6:30 am-8:55 am

2 stops19h 25m

Rome Fiumicino

Wed 11/19

1:15 pm-2:24 pm

2 stops32h 09m

$532

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Tue 12/2

8:00 am-7:45 am

1 stop16h 45m

Rome Fiumicino

Fri 12/12

1:10 pm-5:29 pm

2 stops35h 19m

$532

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Wed 11/12

11:36 am-10:55 am

2 stops16h 19m

Rome Fiumicino

Wed 11/19

1:15 pm-2:21 pm

2 stops32h 06m

$532

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 11/30

8:00 am-7:45 am

1 stop16h 45m

Rome Fiumicino

Sun 12/7

1:10 pm-9:58 pm

2 stops39h 48m

$532

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Sun 11/30

8:00 am-7:45 am

1 stop16h 45m

Rome Fiumicino

Sun 12/7

1:10 pm-9:22 pm

2 stops39h 12m

$532

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 12/2

4:05 pm-10:55 am

1 stop11h 50m

Rome Fiumicino

Fri 12/12

1:10 pm-3:40 pm

2 stops33h 30m

$534

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 12/2

6:42 pm-7:45 am

1 stop30h 03m

Rome Fiumicino

Sun 12/14

1:10 pm-3:29 pm

2 stops33h 19m

$539

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 12/2

1:00 pm-7:45 am

1 stop11h 45m

Rome Fiumicino

Tue 12/16

1:10 pm-12:15 pm

2 stops30h 05m

$539

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 12/2

5:27 pm-7:45 am

1 stop31h 18m

Rome Fiumicino

Mon 12/15

10:55 am-3:29 pm

1 stop35h 34m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, June is the cheapest month in which you can book a flight from Missouri to Rome (average of $450). Flying from Missouri to Rome in July is currently the most expensive (average of $999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ROM?

Find hourly flight availability from Missouri to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 17, 2025.

One of the essential ways to save on airfare from Missouri to Rome is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 31% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 11h 50m. United Airlines provides one of the quickest options available for as low as $534. There are 5050 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is Scandinavian Airlines, with whom users have recently found tickets for as low as $369. However, be on the lookout for offers from American Airlines and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Lambert-St Louis - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Kansas City - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, June is the cheapest month in which you can book a flight from Missouri to Rome (average of $450). Flying from Missouri to Rome in July is currently the most expensive (average of $999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Gaeta
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Rome

Discover the top 9 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest$536Average$1,215FlexibilityNo cancel feeOn-time77%
DeltaCheapest$554Average$868FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$559Average$1,096FlexibilityNo cancel feeOn-time69%
KLMCheapest$604Average$1,065FlexibilityNo cancel feeOn-time75%
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$665Average$1,181FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$671Average$1,198FlexibilityNo cancel feeOn-time76%
Air CanadaCheapest$705Average$1,167FlexibilityNo cancel feeOn-time67%
British AirwaysCheapest$711Average$1,113FlexibilityNo cancel feeOn-time70%

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