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$270+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — ROM
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmSTL - FCO
2 stops16h 40mLufthansa
Wed 1/147:05 amFCO - STL
2 stops23h 54mLufthansa
Deal found 12/16$667
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:00 pmSGF - FCO
2 stops39h 25mUnited Airlines
Thu 1/810:55 amFCO - SGF
2 stops41h 49mUnited Airlines
Deal found 12/17$695
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:29 amSTL - FCO
1 stop18h 26mDelta
Wed 1/1412:45 pmFCO - STL
2 stops17h 54mDelta
Deal found 12/17$701
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 amCOU - FCO
2 stops16h 45mUnited Airlines
Mon 1/1212:20 pmFCO - COU
2 stops39h 13mUnited Airlines
Deal found 12/17$715
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 amCOU - FCO
2 stops16h 45mUnited Airlines
Fri 1/97:00 amFCO - COU
2 stops34h 42mUnited Airlines
Deal found 12/17$793
This Ovago deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:05 amCOU - FCO
2 stops17h 25mMultiple Airlines
Sun 1/1111:00 amFCO - COU
2 stops17h 37mMultiple Airlines
Deal found 12/17$882
This Ovago deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:34 pmCOU - FCO
2 stops16h 41mLufthansa
Sat 1/1010:55 amFCO - COU
2 stops30h 47mLufthansa
Deal found 12/17$894
This Ovago deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:47 pmMCI - FCO
1 stop12h 43mLufthansa
Wed 1/72:20 pmFCO - MCI
2 stops34h 21mLufthansa
Deal found 12/16$1,046
This KAYAK deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:50 amCOU - FCO
1 stop20h 55mMultiple Airlines
Mon 1/1211:20 amFCO - COU
2 stops30h 22mMultiple Airlines
Deal found 12/17$1,088
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:40 pmMCI - FCO
2 stops26h 20mUnited Airlines
Tue 12/239:45 amFCO - MCI
2 stops43h 05mUnited Airlines
Deal found 12/15$1,096
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:47 pmMCI - FCO
1 stop12h 43mBrussels Airlines
Wed 1/78:25 amFCO - MCI
2 stops18h 31mBrussels Airlines
Deal found 12/15$1,108
This Finnair deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amMCI - FCO
1 stop20h 00mMultiple Airlines
Tue 12/2311:00 amFCO - MCI
2 stops19h 53mMultiple Airlines
Deal found 12/15$1,139

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$437
(Kiwi.com)

One-way from

$270
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$820
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($346 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($53 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Missouri

Fly to

Rome

Route

Depart

Return

Price

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sun 3/1

6:55 pm-7:45 am

1 stop29h 50m

Rome Fiumicino

Mon 3/9

10:15 am-3:29 pm

1 stop35h 14m

$486

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sat 1/31

11:22 am-7:55 am

1 stop13h 33m

Rome Fiumicino

Sat 2/7

11:15 am-2:30 pm

2 stops34h 15m

$487

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sun 3/1

6:55 pm-11:00 pm

2 stops21h 05m

Rome Fiumicino

Mon 3/9

7:05 am-11:51 pm

2 stops22h 46m

$491

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Wed 1/14

3:14 pm-6:15 pm

2 stops20h 01m

Rome Fiumicino

Wed 1/21

7:05 am-9:58 pm

2 stops21h 53m

$491

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Sun 3/1

11:20 am-7:45 am

1 stop13h 25m

Rome Fiumicino

Mon 3/9

10:15 am-8:59 pm

2 stops40h 44m

$491

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Fri 1/30

3:14 pm-6:15 pm

2 stops20h 01m

Rome Fiumicino

Tue 2/3

7:05 am-9:58 pm

2 stops21h 53m

$491

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Sat 1/31

6:15 am-7:55 am

2 stops18h 40m

Rome Fiumicino

Sat 2/7

11:15 am-2:38 pm

2 stops34h 23m

$492

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Sat 1/31

8:09 am-8:30 am

2 stops17h 21m

Rome Fiumicino

Sat 2/7

11:15 am-9:37 pm

2 stops41h 22m

$492

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Thu 1/29

5:10 pm-9:25 am

2 stops33h 15m

Rome Fiumicino

Thu 2/5

12:50 pm-8:33 pm

2 stops38h 43m

$494

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sat 1/17

8:30 am-8:30 am

1 stop17h 00m

Rome Fiumicino

Fri 1/30

7:05 am-1:55 pm

1 stop13h 50m

$495

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 52 results
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $468). Flying from Missouri to Rome in July is currently the most expensive (average of $999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ROM?

Find hourly flight availability from Missouri to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Missouri to Rome is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 31% on airfare.

How much does it cost to fly round-trip from Missouri to Rome?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 14h 08m. United Airlines provides one of the quickest options available for as low as $507. There are 5199 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $428. However, be on the lookout for offers from Iberia and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Lambert-St Louis - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Kansas City - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $468). Flying from Missouri to Rome in July is currently the most expensive (average of $999). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Rome

Discover the top 9 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$987FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$506Average$987FlexibilityNo cancel feeOn-time76%
IberiaCheapest$536Average$1,298FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$549Average$1,079FlexibilityNo cancel feeOn-time69%
KLMCheapest$555Average$956FlexibilityNo cancel feeOn-time75%
DeltaCheapest$587Average$911FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$665Average$1,128FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$705Average$1,157FlexibilityNo cancel feeOn-time67%

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