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$298+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:59 am
MCI
-
FCO
1 stop16h 46m
Air France
Tue 3/178:20 am
FCO
-
MCI
2 stops18h 30m
Air France
Deal found 2/1$478
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:05 pm
STL
-
FCO
1 stop12h 00m
Multiple Airlines
Wed 3/117:05 am
FCO
-
STL
1 stop13h 50m
Multiple Airlines
Deal found 2/1$479
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:41 am
STL
-
FCO
1 stop17h 04m
United Airlines
Tue 3/1012:10 pm
FCO
-
STL
2 stops34h 50m
United Airlines
Deal found 2/3$493
This Cheapflightsfares deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/34:49 pm
STL
-
FCO
2 stops18h 26m
Lufthansa
Tue 3/109:45 am
FCO
-
STL
2 stops20h 06m
Lufthansa
Deal found 2/3$495
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/34:05 pm
STL
-
FCO
1 stop11h 50m
Multiple Airlines
Tue 3/109:45 am
FCO
-
STL
1 stop35h 10m
Multiple Airlines
Deal found 2/1$500
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:25 am
STL
-
FCO
2 stops21h 30m
Air Canada
Tue 3/1012:10 pm
FCO
-
STL
2 stops35h 50m
Air Canada
Deal found 2/1$502
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:15 am
COU
-
FCO
2 stops15h 15m
United Airlines
Wed 3/257:05 am
FCO
-
COU
2 stops20h 28m
United Airlines
Deal found 2/1$512
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:30 pm
MCI
-
FCO
1 stop32h 00m
United Airlines
Sun 3/89:45 am
FCO
-
MCI
1 stop18h 14m
United Airlines
Deal found 1/31$514
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:15 am
MCI
-
FCO
2 stops27h 00m
United Airlines
Wed 3/257:05 am
FCO
-
MCI
2 stops35h 14m
United Airlines
Deal found 2/2$516
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:38 pm
MCI
-
FCO
2 stops26h 37m
Iberia
Thu 4/2310:00 am
FCO
-
MCI
1 stop14h 29m
Iberia
Deal found 2/2$524
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/161:56 pm
MCI
-
FCO
2 stops21h 44m
United Airlines
Wed 3/259:45 am
FCO
-
MCI
2 stops32h 34m
United Airlines
Deal found 2/2$529
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:05 pm
STL
-
FCO
2 stops33h 50m
Multiple Airlines
Tue 3/248:05 pm
FCO
-
STL
2 stops27h 55m
Multiple Airlines
Deal found 2/3$530

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$478
(Kiwi.com)

One-way from

$298
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$680
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($366 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($56 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Missouri

Fly to

Rome

Route

Depart

Return

Price

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 3/3

7:41 am-7:45 am

1 stop17h 04m

Rome Fiumicino

Tue 3/10

9:45 am-6:00 pm

1 stop14h 15m

$508

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Wed 3/18

11:15 am-8:30 am

2 stops15h 15m

Rome Fiumicino

Wed 3/25

7:05 am-9:33 pm

2 stops20h 28m

$512

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 3/1

5:30 pm-8:30 am

1 stop32h 00m

Rome Fiumicino

Sun 3/8

9:45 am-9:59 pm

1 stop18h 14m

$514

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Tue 3/10

1:27 pm-5:55 pm

2 stops22h 28m

Rome Fiumicino

Wed 3/18

11:00 am-10:46 am

2 stops29h 46m

$545

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Wed 3/18

9:35 am-8:45 am

1 stop17h 10m

Rome Fiumicino

Wed 3/25

9:05 am-12:12 am

1 stop21h 07m

$608

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 3/18

10:00 am-8:30 am

2 stops16h 30m

Rome Fiumicino

Wed 3/25

7:05 am-6:00 pm

2 stops16h 55m

$609

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Wed 3/18

11:33 am-8:30 am

2 stops14h 57m

Rome Fiumicino

Wed 3/25

10:30 am-10:36 am

2 stops30h 06m

$612

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 3/18

10:50 am-8:45 am

2 stops15h 55m

Rome Fiumicino

Thu 3/26

9:05 am-4:32 pm

1 stop13h 27m

$613

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Tue 3/10

6:55 pm-9:30 am

1 stop32h 35m

Rome Fiumicino

Wed 3/18

9:05 am-9:43 pm

1 stop18h 38m

$615

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Wed 3/11

8:00 am-8:30 am

2 stops18h 30m

Rome Fiumicino

Sun 3/15

2:20 pm-2:06 pm

2 stops53h 46m

$625

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in July is currently the most expensive (average of $995). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 15h 55m. United Airlines provides one of the quickest options available for as low as $613. There are 5050 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $428. However, be on the lookout for offers from Iberia and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $455). Flying from Missouri to Rome in July is currently the most expensive (average of $995). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Rome

Discover the top 9 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$888FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$506Average$987FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$943FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$514Average$1,026FlexibilityNo cancel feeOn-time69%
DeltaCheapest$566Average$891FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$665Average$1,105FlexibilityNo cancel feeOn-time71%
IberiaCheapest$692Average$1,323FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$705Average$1,170FlexibilityNo cancel feeOn-time67%

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