$327+ Cheap flights from Missouri to Rome (ROM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
Oct 28 — Nov 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Rome with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Rome
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to RomeExplore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:30 am -
1 stop16h 15m
Wed 11/251:15 pm -
2 stops28h 17m
Deal found 9/23![United Airlines logo]()
$576
This Air Canada deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:30 am -
2 stops17h 25m
Wed 11/251:15 pm -
2 stops28h 17m
Deal found 9/23![Multiple Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:59 am -
1 stop14h 56m
Tue 1/1211:15 am -
2 stops34h 13m
Deal found 9/23![United Airlines logo]()
$581
This Justfly.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:30 am -
2 stops20h 25m
Tue 1/1211:15 am -
2 stops31h 58m
Deal found 9/23![Air Canada logo]()
$589
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:29 pm -
2 stops17h 21m
Wed 11/1811:00 am -
1 stop16h 26m
Deal found 9/24![American Airlines logo]()
$593
This FlightHub deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:43 am -
2 stops20h 37m
Wed 11/1811:00 am -
1 stop16h 50m
Deal found 9/23![British Airways logo]()
$593
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop19h 15m
Wed 11/2510:00 am -
1 stop14h 14m
Deal found 9/23![Delta logo]()
$596
This Iberia deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:03 am -
1 stop16h 42m
Wed 11/181:10 pm -
1 stop17h 27m
Deal found 9/23![Iberia logo]()
$596
This Air Canada deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:05 pm -
1 stop33h 50m
Tue 11/2411:15 am -
1 stop35h 11m
Deal found 9/24![Air Canada logo]()
$598
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:49 am -
2 stops15h 06m
Wed 11/1811:00 am -
2 stops17h 51m
Deal found 9/23![United Airlines logo]()
$600
This Expedia deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:35 am -
2 stops20h 55m
Tue 11/241:10 pm -
1 stop15h 49m
Deal found 9/24![Iberia logo]()
$605
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop18h 55m
Fri 11/277:05 am -
1 stop13h 40m
Deal found 9/23![United Airlines logo]()
$610
Best flights from Missouri to RomeDiscover carefully curated flight deals from Missouri to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
Discover carefully curated flight deals from Missouri to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
This KLM deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:25 pm -
1 stop13h 55m
Mon 11/235:20 pm -
2 stops30h 13m
Deal found 9/23![KLM logo]()
$660
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop18h 45m
Tue 11/1711:15 am -
2 stops30h 07m
Deal found 9/25![United Airlines logo]()
$731
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3010:45 am -
1 stop15h 50m
Fri 1/151:30 pm -
1 stop17h 09m
Deal found 9/27![Delta logo]()
$747
This KLM deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1012:00 pm -
2 stops16h 30m
Thu 2/181:30 pm -
1 stop15h 56m
Deal found 9/27![Multiple Airlines logo]()
$755
This Expedia deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:10 pm -
2 stops43h 35m
Sat 11/146:50 pm -
2 stops35h 20m
Deal found 9/23![Lufthansa logo]()
$756
This Finnair deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:20 pm -
1 stop13h 25m
Mon 11/26:40 pm -
2 stops32h 39m
Deal found 9/27![Finnair logo]()
$880
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:00 am -
2 stops17h 55m
Wed 11/187:05 am -
1 stop13h 40m
Deal found 9/27![United Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops18h 45m
Fri 11/2712:30 pm -
1 stop14h 01m
Deal found 9/26![Delta logo]()
$751
This United deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/65:20 pm -
1 stop31h 35m
Sun 2/147:05 am -
1 stop13h 40m
Deal found 9/25![Multiple Airlines logo]()
$801
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:25 pm -
1 stop15h 30m
Wed 11/189:55 am -
2 stops20h 15m
Deal found 9/27![United Airlines logo]()
$744
This KLM deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:35 am -
1 stop17h 45m
Wed 2/101:30 pm -
1 stop17h 28m
Deal found 9/25![KLM logo]()
$832
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 pm -
1 stop11h 45m
Sat 11/71:30 pm -
1 stop17h 24m
Deal found 9/24![Delta logo]()
$797
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/91:34 pm -
1 stop15h 21m
Mon 11/162:10 pm -
2 stops37h 37m
Deal found 9/26![United Airlines logo]()
$756
This Finnair deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/412:03 pm -
2 stops22h 52m
Mon 3/156:40 pm -
2 stops35h 59m
Deal found 9/26![Finnair logo]()
$958
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:42 am -
1 stop13h 33m
Sat 12/121:30 pm -
1 stop15h 09m
Deal found 9/27![Delta logo]()
$797
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:25 am -
1 stop13h 20m
Sat 12/1211:15 am -
2 stops30h 35m
Deal found 9/24![United Airlines logo]()
$781
This Turkish Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:00 am -
2 stops27h 25m
Wed 10/286:55 am -
2 stops30h 50m
Deal found 9/27![Multiple Airlines logo]()
$1,021
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/137:00 am -
1 stop21h 20m
Sat 2/276:10 am -
2 stops22h 08m
Deal found 9/26![Delta logo]()
$851
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:25 pm -
1 stop12h 05m
Fri 1/157:05 am -
1 stop13h 40m
Deal found 9/27![United Airlines logo]()
$785
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:55 pm -
2 stops30h 00m
Sun 1/171:15 pm -
2 stops39h 32m
Deal found 9/25![United Airlines logo]()
$792
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/39:52 am -
1 stop15h 23m
Sat 1/1610:25 am -
1 stop14h 36m
Deal found 9/27![Delta logo]()
$942
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:34 pm -
1 stop15h 21m
Sun 11/157:05 am -
2 stops19h 50m
Deal found 9/24![United Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/241:04 pm -
1 stop11h 41m
Tue 3/911:15 am -
2 stops40h 15m
Deal found 9/24![United Airlines logo]()
$795
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:00 pm -
1 stop12h 20m
Sat 11/1410:25 am -
1 stop18h 11m
Deal found 9/24![Delta logo]()
$972
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/21:04 pm -
1 stop11h 41m
Tue 3/911:15 am -
2 stops34h 16m
Deal found 9/27![United Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:11 am -
1 stop13h 34m
Sat 11/149:45 am -
1 stop35h 48m
Deal found 9/23![United Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/196:37 pm -
2 stops55h 18m
Mon 3/19:45 am -
1 stop13h 39m
Deal found 9/27![United Airlines logo]()
$810
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/264:30 pm -
1 stop36h 50m
Sat 4/36:50 am -
2 stops15h 48m
Deal found 9/23![United Airlines logo]()
$825
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:02 pm -
1 stop31h 43m
Sat 1/97:05 am -
2 stops32h 51m
Deal found 9/23![United Airlines logo]()
$832
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/128:00 am -
2 stops17h 55m
Sat 2/209:45 am -
1 stop18h 59m
Deal found 9/24![United Airlines logo]()
$855
Last-minute flights from Missouri to RomeDiscover last-minute flight deals from Missouri to Rome. Data last updated September 28, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Rome. Data last updated September 28, 2026 and is based on user searches.
This British Airways deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:00 am -
1 stop15h 50m
Tue 10/206:50 am -
1 stop19h 40m
Deal found 9/23![British Airways logo]()
$705
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:36 pm -
1 stop15h 44m
Tue 10/208:00 am -
2 stops18h 41m
Deal found 9/23![United Airlines logo]()
$711
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:05 am -
2 stops14h 50m
Tue 10/2010:00 am -
2 stops17h 51m
Deal found 9/23![Delta logo]()
$721
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:22 am -
1 stop16h 28m
Thu 10/151:30 pm -
1 stop17h 29m
Deal found 9/23![American Airlines logo]()
$695
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am -
1 stop17h 35m
Thu 10/159:00 am -
2 stops21h 54m
Deal found 9/23![Delta logo]()
$699
This Ovago deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:10 pm -
1 stop14h 05m
Mon 11/26:50 pm -
2 stops33h 50m
Deal found 9/24![Lufthansa logo]()
$691
This Ovago deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:55 am -
2 stops17h 20m
Mon 11/27:05 am -
2 stops20h 54m
Deal found 9/24![Multiple Airlines logo]()
$733
This FlightHub deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:40 pm -
2 stops35h 15m
Mon 11/26:50 pm -
2 stops33h 50m
Deal found 9/23![Multiple Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:40 am -
1 stop16h 05m
Fri 11/67:05 am -
1 stop13h 40m
Deal found 9/24![United Airlines logo]()
$735
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:21 pm -
2 stops15h 34m
Tue 11/1011:00 am -
2 stops18h 02m
Deal found 9/27![American Airlines logo]()
$736
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:59 am -
1 stop18h 56m
Wed 11/117:05 am -
1 stop13h 40m
Deal found 9/25![United Airlines logo]()
$734
This KLM deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:25 pm -
1 stop13h 55m
Mon 11/235:20 pm -
2 stops30h 13m
Deal found 9/23![KLM logo]()
$660
One-way flights from Missouri to RomeSearch for one-way flight options from Missouri to Rome. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
Search for one-way flight options from Missouri to Rome. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:43 pm -
3 stops38h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$327
This Expedia deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/72:00 pm -
1 stop12h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![British Airways logo]()
$330
This FlightHub deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/71:45 pm -
2 stops20h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![British Airways logo]()
$336
This Expedia deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/145:27 pm -
2 stops17h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![British Airways logo]()
$339
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/79:00 am -
1 stop19h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Delta logo]()
$340
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/68:25 am -
2 stops41h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![United Airlines logo]()
$344
This oojo deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/65:20 pm -
1 stop31h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Lufthansa logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:32 pm -
3 stops39h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:44 pm -
2 stops35h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$381
This FlightHub deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2510:00 am -
2 stops28h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![British Airways logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:43 pm -
3 stops41h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:30 am -
1 stop20h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Delta logo]()
$397
Find flight deals from Missouri to Rome
Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated September 28, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $576 (United Airlines) |
One-way from | $327 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $1,314 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityRome
MCI Kansas City - FCO Rome Fiumicino
MCIFCO
Kansas City
Wed 10/28
8:43 pm-5:05 pm
3 stops38h 22m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$327
St. LouisRome
STL Lambert-St Louis - FCO Rome Fiumicino
STLFCO
Lambert-St Louis
Sun 3/7
5:27 pm-8:05 pm
2 stops19h 38m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$336
St. LouisRome
STL Lambert-St Louis - FCO Rome Fiumicino
STLFCO
Lambert-St Louis
Sun 2/14
5:27 pm-5:50 pm
2 stops17h 23m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$339
St. LouisRome
STL Lambert-St Louis - FCO Rome Fiumicino
STLFCO
Lambert-St Louis
Sun 2/7
9:00 am-11:20 am
1 stop19h 20m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$340
St. LouisRome
STL Lambert-St Louis - FCO Rome Fiumicino
STLFCO
Lambert-St Louis
Sun 2/14
9:00 am-11:20 am
1 stop19h 20m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$340
St. LouisRome
STL Lambert-St Louis - FCO Rome Fiumicino
STLFCO
Lambert-St Louis
Sat 2/6
8:25 am-8:55 am
2 stops41h 30m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$344
Kansas CityRome
MCI Kansas City - FCO Rome Fiumicino
MCIFCO
Kansas City
Tue 12/29
6:30 am-9:35 am
1 stop20h 05m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$397
Quickest round-trip
Kansas CityRome
MCI Kansas City - FCO Rome Fiumicino
MCIFCO
Kansas City
Sun 2/28
1:04 pm-7:45 am
1 stop11h 41m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$397
Kansas CityRome
MCI Kansas City - FCO Rome Fiumicino
MCIFCO
Kansas City
Tue 12/29
12:28 pm-2:35 pm
2 stops19h 07m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$411
Kansas CityRome
MCI Kansas City - FCO Rome Fiumicino
MCIFCO
Kansas City
Sat 11/7
11:22 am-8:55 am
2 stops38h 33m
Rome Fiumicino
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$456
Showing 1-10 of 43 resultsSorted by cheapest first
Best time to book a flight from Missouri to Rome
Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
STL-FCO
MCI-FCO
SGF-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Rome
USMO-ROM
STL-FCO
MCI-FCO
SGF-FCO
What is the cheapest month to book a flight from Missouri to Rome?
Currently, February is the cheapest month in which you can book a flight from Missouri to Rome (average of $525). Flying from Missouri to Rome in June is currently the most expensive (average of $1,610). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Rome?
Airfare is below average for this route at the moment.
Missouri to Rome flights typically cost between $1,038 and $1,304 in November.The cheapest round-trip price found within the last 5 days was $576 on United Airlines (Nov 15-Nov 25).
How far ahead should I book a flight from Missouri to Rome?
The best time to book flights from Missouri to Rome is 33 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Rome?
Book flights to Rome if you plan to visit one of these locationsFiumicino
Civitavecchia
Montepulciano
Santa Marinella
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Rome flight routes
Top destinations
Alternative routes for Missouri to Rome
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Rome by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Rome by cabin class
Find flights from Missouri to Rome, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Rome flights
Browse other Missouri and Rome flight options. Last updated on September 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Rome
Explore flights to Rome departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 28, 2026.
Missouri to Rome flights
Consider these flights traveling from Missouri to Rome.
Top 7 airlines flying from Missouri to Rome
Discover the top 7 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$472 | Average$1,186 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$500 | Average$993 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$506 | Average$934 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$514 | Average$1,195 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$596 | Average$1,338 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$810 | Average$1,225 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$850 | Average$1,330 | FlexibilityNo cancel fee | On-time71% |