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$311+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ROM
Feb 4 — Feb 111
Wed 2/4
Wed 2/11
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 5, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/112:35 pmMCI - FCO
1 stop12h 55mLufthansa
Mon 2/1612:20 pmFCO - MCI
2 stops16h 39mLufthansa
Deal found 1/3$443
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:32 amMCI - FCO
2 stops17h 53mLufthansa
Wed 2/259:45 amFCO - MCI
1 stop14h 48mLufthansa
Deal found 1/4$451
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:32 amMCI - FCO
2 stops18h 53mLufthansa
Fri 2/279:45 amFCO - MCI
1 stop19h 14mLufthansa
Deal found 1/4$459
This Cheapflightsfares deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2211:32 amMCI - FCO
1 stop13h 13mLufthansa
Thu 3/127:05 amFCO - MCI
2 stops19h 36mLufthansa
Deal found 1/3$487
This United Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/183:22 pmMCI - FCO
1 stop33h 23mUnited Airlines
Wed 2/2511:15 amFCO - MCI
2 stops35h 30mUnited Airlines
Deal found 1/4$488
This United Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:55 pmSTL - FCO
2 stops31h 30mUnited Airlines
Mon 2/2311:15 amFCO - STL
2 stops40h 50mUnited Airlines
Deal found 1/4$491
This United Airlines deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:49 pmSTL - FCO
2 stops56h 41mUnited Airlines
Tue 2/241:10 pmFCO - STL
1 stop33h 19mUnited Airlines
Deal found 1/3$493
This Cheapflightsfares deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/312:44 pmSTL - FCO
2 stops16h 41mLufthansa
Tue 2/107:05 amFCO - STL
2 stops22h 53mLufthansa
Deal found 1/4$494
This Cheapflightsfares deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:37 pmMCI - FCO
2 stops15h 23mLufthansa
Thu 3/127:05 amFCO - MCI
2 stops19h 36mLufthansa
Deal found 1/4$494
This Cheapflightsfares deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:40 pmSTL - FCO
2 stops16h 35mLufthansa
Sat 2/1410:30 amFCO - STL
1 stop20h 35mLufthansa
Deal found 1/4$496
This oojo deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:38 pmMCI - FCO
2 stops21h 17mBritish Airways
Thu 3/1211:35 amFCO - MCI
1 stop17h 14mBritish Airways
Deal found 1/4$496
This American Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/311:13 pmSGF - FCO
2 stops17h 17mAmerican Airlines
Fri 2/131:10 pmFCO - SGF
2 stops17h 45mAmerican Airlines
Deal found 1/2$496

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated January 5, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$443
(Kiwi.com)

One-way from

$311
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$693
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($360 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 5, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Missouri

Fly to

Rome

Route

Depart

Return

Price

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 2/22

12:37 pm-8:30 am

1 stop12h 53m

Rome Fiumicino

Thu 3/12

7:05 am-8:41 pm

2 stops19h 36m

$487

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sat 2/21

6:25 am-7:45 am

1 stop18h 20m

Rome Fiumicino

Sun 3/1

1:15 pm-9:05 pm

2 stops38h 50m

$488

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Tue 2/3

12:35 pm-12:25 pm

2 stops16h 50m

Rome Fiumicino

Tue 2/10

7:05 am-9:59 pm

2 stops21h 54m

$494

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Sat 1/31

1:13 pm-1:30 pm

2 stops17h 17m

Rome Fiumicino

Fri 2/13

1:10 pm-11:55 pm

2 stops17h 45m

$496

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 2/17

6:25 am-9:25 am

2 stops20h 00m

Rome Fiumicino

Tue 2/24

1:10 pm-12:05 am

2 stops41h 55m

$496

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Wed 2/18

12:37 pm-12:25 pm

2 stops16h 48m

Rome Fiumicino

Wed 2/25

7:00 am-9:59 pm

2 stops21h 59m

$496

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Sat 1/31

6:00 am-9:45 am

2 stops20h 45m

Rome Fiumicino

Fri 2/13

12:40 pm-9:47 pm

1 stop16h 07m

$499

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 2/18

6:55 pm-7:45 am

1 stop29h 50m

Rome Fiumicino

Wed 2/25

9:45 am-10:59 pm

2 stops20h 14m

$507

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 2/1

12:35 pm-8:30 am

1 stop12h 55m

Rome Fiumicino

Mon 2/16

7:05 am-10:36 am

2 stops34h 31m

$507

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Tue 2/17

6:00 am-10:30 am

1 stop21h 30m

Rome Fiumicino

Tue 2/24

12:40 pm-9:47 pm

1 stop16h 07m

$508

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/3

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $465). Flying from Missouri to Rome in July is currently the most expensive (average of $995). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Rome?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 12h 53m. Lufthansa provides one of the quickest options available for as low as $487. There are 5199 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $428. However, be on the lookout for offers from Iberia and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Rome (average of $465). Flying from Missouri to Rome in July is currently the most expensive (average of $995). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Rome

Discover the top 9 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$924FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$506Average$987FlexibilityNo cancel feeOn-time76%
IberiaCheapest$536Average$1,226FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$549Average$1,073FlexibilityNo cancel feeOn-time69%
KLMCheapest$555Average$943FlexibilityNo cancel feeOn-time75%
DeltaCheapest$587Average$907FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$665Average$1,127FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$705Average$1,170FlexibilityNo cancel feeOn-time67%

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