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$278+ Cheap flights from Missouri to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — ROM
Jul 21 — Jul 281
Tue 7/21
Tue 7/28
1 adult, Economy
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Cheap flight deals from Missouri to Rome

Cheapest flights from Missouri to Rome
Explore the most affordable flight options available from Missouri to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.

This eDestinos deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:16 am
STL
-
FCO
1 stop18h 49m
Iberia
Thu 8/201:10 pm
FCO
-
STL
1 stop16h 31m
Iberia
Deal found 6/18$725
This lol.travel deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/912:45 pm
STL
-
FCO
1 stop16h 20m
Finnair
Tue 8/2510:00 am
FCO
-
STL
1 stop21h 14m
Finnair
Deal found 6/17$726
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:40 am
STL
-
FCO
1 stop16h 50m
United Airlines
Wed 11/181:15 pm
FCO
-
STL
2 stops30h 25m
United Airlines
Deal found 6/21$770
This oojo deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/83:40 pm
STL
-
FCO
1 stop14h 00m
Lufthansa
Wed 11/187:05 am
FCO
-
STL
1 stop13h 40m
Lufthansa
Deal found 6/21$772
This FlightHub deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am
STL
-
FCO
2 stops19h 55m
Air Canada
Wed 11/181:15 pm
FCO
-
STL
2 stops40h 54m
Air Canada
Deal found 6/20$773
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:33 am
STL
-
FCO
1 stop17h 12m
United Airlines
Tue 1/1211:15 am
FCO
-
STL
2 stops32h 25m
United Airlines
Deal found 6/20$775
This FlightHub deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:15 pm
STL
-
FCO
2 stops57h 40m
Air Canada
Wed 11/181:15 pm
FCO
-
STL
2 stops40h 54m
Air Canada
Deal found 6/20$777
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:05 pm
STL
-
FCO
1 stop15h 50m
United Airlines
Wed 11/187:05 am
FCO
-
STL
1 stop13h 40m
United Airlines
Deal found 6/21$778
This Justfly.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:40 pm
STL
-
FCO
2 stops35h 35m
Air Canada
Fri 10/2311:30 am
FCO
-
STL
2 stops35h 13m
Air Canada
Deal found 6/20$779
This Gotogate deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:10 pm
STL
-
FCO
1 stop14h 05m
Multiple Airlines
Fri 10/2311:30 am
FCO
-
STL
1 stop14h 11m
Multiple Airlines
Deal found 6/20$780
This FlightHub deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:15 pm
STL
-
FCO
2 stops33h 40m
Air Canada
Tue 1/1211:15 am
FCO
-
STL
2 stops35h 26m
Air Canada
Deal found 6/19$782
This lol.travel deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:16 pm
MCI
-
FCO
1 stop16h 49m
Finnair
Wed 8/1910:30 am
FCO
-
MCI
2 stops21h 05m
Finnair
Deal found 6/18$813

Find flight deals from Missouri to Rome

Keep the following information in mind while searching for Missouri to Rome flight deals. Data was last updated June 21, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$725
(eDestinos)

One-way from

$278
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$1,686
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Rome (ROM)
Search Deals
One-way flight from Missouri to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($403 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($66 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Missouri to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 8/5

12:10 pm-9:15 am

1 stop14h 05m

Rome Fiumicino

Wed 8/19

2:20 pm-6:42 pm

1 stop35h 22m

$816

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Mon 11/9

11:44 am-8:30 am

1 stop13h 46m

Rome Fiumicino

Thu 11/12

9:55 am-10:29 pm

2 stops19h 34m

$862

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Mon 12/7

6:00 am-7:45 am

1 stop18h 45m

Rome Fiumicino

Thu 12/10

9:55 am-12:57 am

2 stops22h 02m

$862

SpringfieldRome

SGF - FCO

SGFFCO

Springfield-Branson

Sun 12/6

11:22 am-7:45 am

1 stop13h 23m

Rome Fiumicino

Wed 12/9

9:45 am-12:57 am

1 stop22h 12m

$864

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 9/1

10:25 am-9:50 pm

2 stops28h 25m

Rome Fiumicino

Thu 9/10

8:10 am-7:45 pm

2 stops18h 35m

$871

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sun 8/16

3:39 pm-10:50 am

1 stop12h 11m

Rome Fiumicino

Sat 8/22

12:45 pm-4:17 pm

2 stops34h 32m

$873

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Sun 10/18

10:35 am-10:50 am

1 stop17h 15m

Rome Fiumicino

Thu 10/29

6:10 am-10:26 pm

2 stops22h 16m

$880

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 10/13

1:30 pm-11:00 am

2 stops14h 30m

Rome Fiumicino

Wed 10/28

10:00 am-11:39 pm

2 stops19h 39m

$883

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Thu 9/3

7:00 am-9:45 pm

2 stops31h 45m

Rome Fiumicino

Mon 9/21

8:10 am-7:45 pm

2 stops18h 35m

$894

ColumbiaRome

COU - FCO

COUFCO

Columbia Regional

Tue 8/4

3:25 pm-7:55 am

1 stop33h 30m

Rome Fiumicino

Tue 8/11

12:25 pm-10:16 am

2 stops52h 51m

$895

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/18

Showing 1-10 of 59 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Rome

What is the cheapest month to book a flight from Missouri to Rome?

Currently, August is the cheapest month in which you can book a flight from Missouri to Rome (average of $287). Flying from Missouri to Rome in June is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Rome?

How far ahead should I book a flight from Missouri to Rome?

The best time to book flights from Missouri to Rome is 36 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Rome?

    A quick flight from Missouri to Rome can take about 14h 05m. Finnair provides one of the quickest options available for as low as $816. There are 5050 mi between Missouri and Rome. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Rome one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $287. However, be on the lookout for offers from United Airlines and Lufthansa, as they are both options that can get you from Missouri to Rome for a low price.

  • What are the most popular routes from Missouri to Rome?

    While some choose either Kansas City - Rome Fiumicino or Springfield-Branson - Rome Fiumicino, Lambert-St Louis - Rome Fiumicino is the most popular route from Missouri to Rome.

  • Can I find deals for flights from Missouri to Rome that include hotel bookings?

    Yes. In addition to deals on Missouri to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Rome.

  • Can I find deals for business class flights from Missouri to Rome?

    Yes. Cheapflights offers flight deals from Missouri to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Rome?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Rome (average of $287). Flying from Missouri to Rome in June is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Montepulciano
Santa Marinella

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Alternative routes for Missouri to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Missouri to Rome

Discover the top 8 airlines that operate flights from Missouri to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$1,217FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$500Average$987FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$825FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$514Average$1,055FlexibilityNo cancel feeOn-time69%
Air CanadaCheapest$564Average$1,225FlexibilityNo cancel feeOn-time67%
DeltaCheapest$566Average$1,179FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$655Average$1,385FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$665Average$1,316FlexibilityNo cancel feeOn-time71%

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