How long is the flight from Des Moines to Quintana Roo?

A quick flight from Des Moines to Quintana Roo can take about 6h 51m. Delta provides one of the quickest options available for as low as $486. Des Moines and Quintana Roo are separated by a distance of 1470 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Des Moines to Quintana Roo one-way?

The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $225. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Des Moines to Quintana Roo for a low price.

In terms of precipitation, rainfall in Quintana Roo ranges from 1.1 - 11.1 inches per month. October is typically the wettest month, when rainfall can reach 11.1 in. April is typically the driest time to visit Quintana Roo when rainfall is around 1.1 in.

If weather is an important factor for your trip to Quintana Roo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 86.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What are the most popular airlines that fly from Des Moines to Quintana Roo?

Before booking your flight from Des Moines to Quintana Roo check out the most popular airlines for this route: American Airlines, United Airlines or Delta.

What airport do you fly from for flights from Des Moines to Quintana Roo?

Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Quintana Roo.

Can I find deals for flights from Des Moines to Quintana Roo that include hotel bookings?

Yes. In addition to deals on Des Moines to Quintana Roo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Quintana Roo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Quintana Roo.

Can I find deals for business class flights from Des Moines to Quintana Roo?

Yes. Cheapflights offers flight deals from Des Moines to Quintana Roo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$225+ Flights from Des Moines to Quintana Roo

Q: How much does it cost to fly round-trip from Des Moines to Quintana Roo?

Airfare is below average for this route at the moment. Des Moines to Quintana Roo flights typically cost between $507 and $796 in February. The cheapest round-trip price found within the last 3 days was $377 on Multiple Airlines (Feb 1-Feb 5).

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheap flight deals from Des Moines to Quintana Roo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$377 (Kiwi.com)
One-way from	$225 (American Airlines)
Popular in	March
Cheapest in	September
Average price	$519

Provider with most accurate pricing for Des Moines-Cancun flight deals.

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Provider most trusted by Cheapflights users for Des Moines-Cancun flights.

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From Des Moines to Quintana Roo

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One-way flight from Des Moines to Quintana Roo

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($46 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).

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Average for round-trip flights in October 2025

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Find flight deals from Des Moines to Quintana Roo

Cheapest flights from Des Moines to Quintana Roo
Explore the most affordable flight options available from Des Moines to Quintana Roo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Tue 11/254:03 pmDSM - CUN

1 stop20h 32mMultiple Airlines

Thu 12/42:36 pmCUN - DSM

1 stop8h 45mMultiple Airlines

Deal found 10/27

$403

Thu 12/112:56 pmDSM - CUN

2 stops22h 27mMultiple Airlines

Thu 12/182:36 pmCUN - DSM

1 stop9h 00mMultiple Airlines

Deal found 10/27

$433

Tue 12/97:44 amDSM - CUN

1 stop7h 28mAmerican Airlines

Tue 12/163:52 pmCUN - DSM

1 stop8h 56mAmerican Airlines

Deal found 10/24

$441

Tue 11/254:03 pmDSM - CUN

1 stop20h 32mMultiple Airlines

Wed 12/32:44 pmCUN - DSM

2 stops31h 52mMultiple Airlines

Deal found 10/27

$442

Fri 11/2812:34 pmDSM - CUN

2 stops24h 01mMultiple Airlines

Thu 12/42:36 pmCUN - DSM

1 stop8h 45mMultiple Airlines

Deal found 10/27

$445

Mon 12/16:53 pmDSM - CUN

1 stop17h 42mMultiple Airlines

Mon 12/152:14 pmCUN - DSM

2 stops49h 26mMultiple Airlines

Deal found 10/25

$448

Tue 12/911:23 amDSM - CUN

1 stop8h 57mAeromexico

Tue 12/168:00 amCUN - DSM

1 stop10h 47mAeromexico

Deal found 10/25

$449

Tue 12/95:00 amDSM - CZM

1 stop8h 50mAmerican Airlines

Tue 12/163:16 pmCZM - DSM

1 stop8h 13mAmerican Airlines

Deal found 10/26

$451

Wed 11/262:00 pmDSM - CUN

1 stop26h 20mMultiple Airlines

Thu 12/42:36 pmCUN - DSM

1 stop8h 45mMultiple Airlines

Deal found 10/27

$453

Mon 12/85:40 amDSM - CUN

1 stop6h 51mAmerican Airlines

Mon 12/153:08 pmCUN - DSM

1 stop9h 21mAmerican Airlines

Deal found 10/25

$464

Wed 12/105:00 amDSM - CZM

1 stop8h 50mAmerican Airlines

Wed 12/172:50 pmCZM - DSM

1 stop8h 09mAmerican Airlines

Deal found 10/26

$491

Mon 12/85:00 amDSM - CZM

1 stop8h 50mAmerican Airlines

Fri 12/195:07 pmCZM - DSM

1 stop6h 28mAmerican Airlines

Deal found 10/26

$499

Best flights from Des Moines to Quintana Roo
Discover carefully curated flight deals from Des Moines to Quintana Roo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2025.

Mon 1/266:54 amDSM - CZM

1 stop8h 06mDelta

Wed 2/43:05 pmCZM - DSM

1 stop7h 26mDelta

Deal found 10/26

$451

Tue 3/38:08 amDSM - CUN

1 stop6h 51mUnited Airlines

Tue 3/1012:27 pmCUN - DSM

1 stop9h 23mUnited Airlines

Deal found 10/26

$486

Mon 1/196:54 amDSM - CZM

1 stop8h 06mDelta

Fri 1/233:05 pmCZM - DSM

2 stops19h 09mDelta

Deal found 10/27

$455

Mon 1/126:54 amDSM - CUN

1 stop8h 31mDelta

Thu 1/2912:25 pmCUN - DSM

1 stop9h 29mDelta

Deal found 10/25

$486

Sat 1/106:48 pmDSM - CZM

2 stops18h 35mUnited Airlines

Sat 1/174:42 pmCZM - DSM

2 stops21h 51mUnited Airlines

Deal found 10/25

$555

Wed 1/285:34 amDSM - CUN

1 stop10h 11mDelta

Tue 2/31:40 pmCUN - DSM

1 stop9h 51mDelta

Deal found 10/26

$486

Thu 2/58:00 amDSM - CZM

2 stops29h 23mUnited Airlines

Tue 2/102:25 pmCZM - DSM

1 stop8h 05mUnited Airlines

Deal found 10/26

$555

Mon 1/196:29 amDSM - CUN

1 stop6h 31mDelta

Fri 1/2311:20 amCUN - DSM

2 stops12h 11mDelta

Deal found 10/27

$486

Mon 1/266:48 pmDSM - CZM

2 stops18h 35mUnited Airlines

Wed 2/42:25 pmCZM - DSM

2 stops9h 19mUnited Airlines

Deal found 10/26

$555

Wed 2/115:34 amDSM - CUN

1 stop10h 11mDelta

Wed 2/183:15 pmCUN - DSM

1 stop7h 12mDelta

Deal found 10/27

$486

Fri 1/166:48 pmDSM - CZM

2 stops18h 10mUnited Airlines

Wed 1/212:25 pmCZM - DSM

2 stops20h 30mUnited Airlines

Deal found 10/25

$555

Tue 12/910:20 amDSM - CUN

2 stops10h 00mDelta

Tue 12/168:00 amCUN - DSM

2 stops13h 46mDelta

Deal found 10/25

$491

Tue 1/136:24 amDSM - CUN

2 stops13h 47mDelta

Wed 1/2112:05 pmCUN - DSM

2 stops11h 26mDelta

Deal found 10/27

$491

Wed 2/187:00 amDSM - CUN

2 stops10h 47mDelta

Tue 2/2412:05 pmCUN - DSM

2 stops11h 23mDelta

Deal found 10/26

$491

Tue 3/36:20 amDSM - CUN

2 stops9h 11mDelta

Tue 3/108:00 amCUN - DSM

2 stops12h 53mDelta

Deal found 10/26

$491

Sat 1/171:03 pmDSM - CUN

2 stops21h 02mDelta

Fri 1/231:43 pmCUN - DSM

1 stop8h 11mDelta

Deal found 10/27

$491

Wed 2/44:21 pmDSM - CZM

2 stops21h 29mDelta

Wed 2/113:05 pmCZM - DSM

1 stop7h 26mDelta

Deal found 10/26

$504

Tue 1/135:34 amDSM - CZM

1 stop8h 16mDelta

Fri 1/233:05 pmCZM - DSM

1 stop7h 26mDelta

Deal found 10/27

$520

Fri 2/65:49 pmDSM - CZM

2 stops20h 01mDelta

Wed 2/113:05 pmCZM - DSM

1 stop7h 26mDelta

Deal found 10/26

$530

Tue 1/135:34 amDSM - CZM

1 stop8h 16mDelta

Sun 1/183:05 pmCZM - DSM

1 stop7h 26mDelta

Deal found 10/27

$545

Mon 1/195:49 pmDSM - CZM

2 stops20h 01mDelta

Wed 1/213:05 pmCZM - DSM

2 stops18h 36mDelta

Deal found 10/27

$550

Wed 2/44:21 pmDSM - CZM

2 stops21h 29mDelta

Mon 2/93:05 pmCZM - DSM

1 stop7h 26mDelta

Deal found 10/26

$553

Last-minute flights from Des Moines to Quintana Roo
Discover last-minute flight deals from Des Moines to Quintana Roo. Data last updated October 27, 2025 and is based on user searches.

Sat 11/16:12 pmDSM - CUN

1 stop16h 51mAmerican Airlines

Wed 11/53:54 pmCUN - DSM

1 stop7h 14mAmerican Airlines

Deal found 10/25

$666

Sat 11/16:12 pmDSM - CUN

2 stops16h 19mAmerican Airlines

Fri 11/73:22 pmCUN - DSM

1 stop8h 37mAmerican Airlines

Deal found 10/25

$671

Sat 11/18:02 amDSM - CUN

2 stops8h 48mUnited Airlines

Wed 11/56:30 amCUN - DSM

2 stops8h 49mUnited Airlines

Deal found 10/25

$696

Sat 11/110:50 amDSM - CUN

1 stop9h 30mDelta

Wed 11/56:00 amCUN - DSM

2 stops12h 44mDelta

Deal found 10/26

$716

Sat 11/17:03 amDSM - CUN

2 stops13h 17mDelta

Fri 11/78:00 amCUN - DSM

2 stops13h 35mDelta

Deal found 10/25

$761

Sat 11/16:00 amDSM - CZM

1 stop6h 58mUnited Airlines

Fri 11/72:25 pmCZM - DSM

1 stop7h 55mUnited Airlines

Deal found 10/26

$861

Sat 11/15:47 amDSM - CZM

2 stops33h 39mAeromexico

Wed 11/52:49 pmCZM - DSM

2 stops31h 41mAeromexico

Deal found 10/26

$1,941

Thu 11/62:13 pmDSM - CUN

1 stop6h 07mDelta

Sun 11/93:10 pmCUN - DSM

1 stop7h 05mDelta

Deal found 10/26

$734

Thu 11/66:50 pmDSM - CUN

2 stops17h 04mUnited Airlines

Sun 11/96:30 amCUN - DSM

2 stops15h 15mUnited Airlines

Deal found 10/26

$786

Thu 11/66:50 pmDSM - CZM

2 stops18h 33mUnited Airlines

Sun 11/92:25 pmCZM - DSM

1 stop7h 55mUnited Airlines

Deal found 10/26

$845

One-way flights from Des Moines to Quintana Roo
Search for one-way flight options from Des Moines to Quintana Roo. Find affordable one-way fares based on user searches. Data last updated October 27, 2025.

Tue 12/95:40 amDSM - CUN

1 stop6h 51mAmerican Airlines

Deal found 10/25

$225

Sun 1/256:54 amDSM - CUN

1 stop8h 31mDelta

Deal found 10/27

$229

Wed 11/262:00 pmDSM - CUN

1 stop26h 20mFrontier

Deal found 10/27

$240

Wed 11/268:00 amDSM - CUN

3 stops52h 35mMultiple Airlines

Deal found 10/27

$249

Sun 1/253:35 pmDSM - CZM

2 stops21h 48mUnited Airlines

Deal found 10/27

$255

Mon 3/1610:55 amDSM - CZM

2 stops27h 10mDelta

Deal found 10/25

$275

Sun 12/287:30 pmDSM - CUN

1 stop17h 01mMultiple Airlines

Deal found 10/25

$275

Wed 3/187:15 amDSM - CUN

1 stop7h 44mUnited Airlines

Deal found 10/25

$284

Wed 11/261:35 pmDSM - CUN

2 stops20h 50mUnited Airlines

Deal found 10/27

$290

Wed 1/286:14 pmDSM - CUN

3 stops41h 13mMultiple Airlines

Deal found 10/25

$299

Tue 3/175:45 amDSM - CZM

1 stop8h 20mDelta

Deal found 10/25

$300

Wed 12/313:00 pmDSM - CUN

3 stops24h 05mMultiple Airlines

Deal found 10/25

$311

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Quintana Roo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 1/26

6:54 am-3:00 pm

1 stop8h 06m

Cozumel

Wed 2/4

3:05 pm-10:31 pm

1 stop7h 26m

$451

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 1/19

6:54 am-3:00 pm

1 stop8h 06m

Cozumel

Fri 1/23

3:05 pm-10:14 am

2 stops19h 09m

$455

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 3/3

8:08 am-3:59 pm

1 stop6h 51m

Cancun

Tue 3/10

12:27 pm-9:50 pm

1 stop9h 23m

$486

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 1/12

6:54 am-4:25 pm

1 stop8h 31m

Cancun

Thu 1/29

12:25 pm-8:54 pm

1 stop9h 29m

$486

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 1/28

5:34 am-4:45 pm

1 stop10h 11m

Cancun

Tue 2/3

1:40 pm-10:31 pm

1 stop9h 51m

$486

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 1/19

6:29 am-2:00 pm

1 stop6h 31m

Cancun

Fri 1/23

11:20 am-10:31 pm

2 stops12h 11m

$486

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 2/11

5:34 am-4:45 pm

1 stop10h 11m

Cancun

Wed 2/18

3:15 pm-9:27 pm

1 stop7h 12m

$486

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 12/9

10:20 am-9:20 pm

2 stops10h 00m

Cancun

Tue 12/16

8:00 am-8:46 pm

2 stops13h 46m

$491

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 1/13

6:24 am-9:11 pm

2 stops13h 47m

Cancun

Wed 1/21

12:05 pm-10:31 pm

2 stops11h 26m

$491

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 2/18

7:00 am-6:47 pm

2 stops10h 47m

Cancun

Tue 2/24

12:05 pm-10:28 pm

2 stops11h 23m

$491

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Showing 1-10 of 33 results

Best time to book a flight from Des Moines to Quintana Roo

Have a flexible travel schedule? Discover the best time to fly to Quintana Roo from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Quintana Roo

What is the cheapest month to book a flight from Des Moines to Quintana Roo?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Quintana Roo (average of $350). Flying from Des Moines to Quintana Roo in August is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to QR?

Unlike in the morning, when flights are generally more expensive, you can save up to 5% on flights from Des Moines to Quintana Roo by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Des Moines to Quintana Roo?

Reviews of airlines servicing Quintana Roo

Read reviews from past customers who have flown Southwest, Delta, and Aeromexico from Des Moines to Quintana Roo. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,238 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,238 reviews

Southwest

8.0

Very good

4,238 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Delta

7.9

Good

7,996 reviews

Southwest

8.0

Very good

4,238 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Aeromexico

7.5

Good

1,678 reviews

Southwest

8.0

Very good

4,238 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

United Airlines

7.4

Good

8,997 reviews

Southwest

8.0

Very good

4,238 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

11,031 reviews

Southwest

8.0

Very good

4,238 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

What airport do you fly from for flights from Des Moines to Quintana Roo?
Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Quintana Roo.
How long is the flight from Des Moines to Quintana Roo?
A quick flight from Des Moines to Quintana Roo can take about 6h 51m. Delta provides one of the quickest options available for as low as $486. Des Moines and Quintana Roo are separated by a distance of 1470 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Des Moines to Quintana Roo one-way?
The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $225. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Des Moines to Quintana Roo for a low price.
Can I find deals for flights from Des Moines to Quintana Roo that include hotel bookings?
Yes. In addition to deals on Des Moines to Quintana Roo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Quintana Roo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Quintana Roo.
Can I find deals for business class flights from Des Moines to Quintana Roo?
Yes. Cheapflights offers flight deals from Des Moines to Quintana Roo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Quintana Roo?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Quintana Roo (average of $350). Flying from Des Moines to Quintana Roo in August is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Des Moines to Quintana Roo

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$398	Average$635	FlexibilityNo cancel fee	On-timeN/A
Aeromexico	Cheapest$410	Average$514	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$439	Average$579	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$468	Average$612	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$547	Average$694	FlexibilityNo cancel fee	On-time63%

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$225+ Cheap flights from Des Moines (DSM) to Quintana Roo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Quintana Roo with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Quintana Roo

Keep the following information in mind while searching for Des Moines to Quintana Roo flight deals. Data was last updated October 27, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Quintana Roo

Cheapest flights from Des Moines to Quintana RooExplore the most affordable flight options available from Des Moines to Quintana Roo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Explore the most affordable flight options available from Des Moines to Quintana Roo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Quintana Roo that are best for you.

Best time to book a flight from Des Moines to Quintana Roo

Have a flexible travel schedule? Discover the best time to fly to Quintana Roo from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Quintana Roo

What is the cheapest month to book a flight from Des Moines to Quintana Roo?

What is the cheapest time of day to fly from DSM to QR?

Find hourly flight availability from Des Moines to Quintana Roo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

How much does it cost to fly round-trip from Des Moines to Quintana Roo?

Reviews of airlines servicing Quintana Roo

Read reviews from past customers who have flown Southwest, Delta, and Aeromexico from Des Moines to Quintana Roo. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Quintana Roo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Quintana Roo?

How long is the flight from Des Moines to Quintana Roo?

What are the cheapest airlines to fly from Des Moines to Quintana Roo one-way?

Can I find deals for flights from Des Moines to Quintana Roo that include hotel bookings?

How can I find direct flights from Des Moines to Quintana Roo?

Can I find deals for business class flights from Des Moines to Quintana Roo?

What is the cheapest month to book a flight from Des Moines to Quintana Roo?

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Alternative routes for Des Moines to Quintana Roo

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Top 5 airlines flying from Des Moines to Quintana Roo

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Cheapest flights from Des Moines to Quintana Roo
Explore the most affordable flight options available from Des Moines to Quintana Roo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.