HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Quintana Roo

$184+ Cheap flights from Des Moines (DSM) to Quintana Roo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CUN
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Quintana Roo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Quintana Roo

Keep the following information in mind while searching for Des Moines to Quintana Roo flight deals. Data was last updated September 17, 2025.

Round-trip from

$360
(Mytrip)

One-way from

$184
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$534
From Des Moines to Quintana Roo
Search Deals
One-way flight from Des Moines to Quintana Roo
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Des Moines to Quintana Roo

Cheapest flights from Des Moines to Quintana Roo
Explore the most affordable flight options available from Des Moines to Quintana Roo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:56 pmDSM - CUN
2 stops18h 41mMultiple Airlines
Thu 12/111:35 pmCUN - DSM
1 stop9h 46mMultiple Airlines
Deal found 9/14$360
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/68:30 amDSM - CUN
2 stops23h 34mMultiple Airlines
Sat 10/119:09 amCUN - DSM
2 stops24h 42mMultiple Airlines
Deal found 9/16$381
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:37 pmDSM - CUN
2 stops35h 56mMultiple Airlines
Wed 10/221:49 pmCUN - DSM
1 stop20h 02mMultiple Airlines
Deal found 9/16$385
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/31:43 pmDSM - CUN
2 stops18h 21mMultiple Airlines
Wed 11/121:35 pmCUN - DSM
1 stop21h 25mMultiple Airlines
Deal found 9/16$387
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:32 pmDSM - CUN
2 stops34h 04mMultiple Airlines
Wed 11/121:35 pmCUN - DSM
1 stop21h 25mMultiple Airlines
Deal found 9/16$391
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/28:47 pmDSM - CUN
2 stops15h 57mMultiple Airlines
Wed 11/121:35 pmCUN - DSM
1 stop21h 25mMultiple Airlines
Deal found 9/16$404
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:32 pmDSM - CUN
2 stops18h 00mMultiple Airlines
Sat 11/81:35 pmCUN - DSM
1 stop21h 25mMultiple Airlines
Deal found 9/16$418
This Aeromexico deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:44 amDSM - CUN
1 stop8h 36mAeromexico
Thu 10/239:11 amCUN - DSM
2 stops13h 19mAeromexico
Deal found 9/15$422
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:00 amDSM - CZM
1 stop8h 50mAmerican Airlines
Tue 12/162:50 pmCZM - DSM
1 stop8h 09mAmerican Airlines
Deal found 9/15$440
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:12 pmDSM - CZM
1 stop20h 41mAmerican Airlines
Sat 11/85:33 pmCZM - DSM
1 stop17h 07mAmerican Airlines
Deal found 9/17$441
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amDSM - CZM
1 stop8h 36mAmerican Airlines
Fri 12/195:07 pmCZM - DSM
1 stop6h 26mAmerican Airlines
Deal found 9/15$469
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:00 amDSM - CZM
1 stop8h 53mAmerican Airlines
Sat 12/62:50 pmCZM - DSM
1 stop8h 09mAmerican Airlines
Deal found 9/15$485

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Quintana Roo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to Quintana Roo that are best for you.

Fly from

Des Moines

Fly to

Quintana Roo

Route

Depart

Return

Price

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 9/30

11:17 am-8:15 pm

1 stop8h 58m

Cancun

Thu 10/23

8:00 am-9:03 pm

2 stops13h 03m

$426

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 10/7

2:13 pm-8:20 pm

1 stop6h 07m

Cancun

Tue 10/14

8:10 am-10:30 pm

2 stops14h 20m

$467

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 12/8

6:00 am-2:36 pm

1 stop8h 36m

Cozumel

Fri 12/19

5:07 pm-11:33 pm

1 stop6h 26m

$469

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 10/7

5:00 am-1:50 pm

1 stop8h 50m

Cancun

Sat 10/11

11:45 am-11:16 pm

2 stops11h 31m

$471

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Sun 11/30

5:00 am-1:53 pm

1 stop8h 53m

Cozumel

Sat 12/6

2:50 pm-10:59 pm

1 stop8h 09m

$485

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 11/26

5:30 am-5:55 pm

1 stop11h 25m

Cancun

Wed 12/3

2:30 pm-9:35 pm

1 stop8h 05m

$486

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 12/9

2:15 pm-9:20 pm

1 stop6h 05m

Cancun

Tue 12/16

8:00 am-1:30 pm

1 stop6h 30m

$486

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 12/9

5:00 am-12:07 pm

1 stop6h 07m

Cancun

Tue 12/16

5:20 pm-11:29 pm

1 stop7h 09m

$486

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 12/8

5:00 am-1:50 pm

1 stop8h 50m

Cozumel

Sun 12/14

2:50 pm-10:48 pm

1 stop7h 58m

$490

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Fri 10/31

6:05 am-12:23 pm

1 stop7h 18m

Cozumel

Fri 11/7

2:25 pm-12:14 pm

2 stops21h 49m

$509

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 35 results
1
2
3
4

Best time to book a flight from Des Moines to Quintana Roo

Have a flexible travel schedule? Discover the best time to fly to Quintana Roo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Quintana Roo

What is the cheapest month to book a flight from Des Moines to Quintana Roo?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Quintana Roo (average of $360). Flying from Des Moines to Quintana Roo in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to QR?

Find hourly flight availability from Des Moines to Quintana Roo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Quintana Roo as you normally would.

How much does it cost to fly round-trip from Des Moines to Quintana Roo?

Reviews of airlines servicing Quintana Roo

Get insights into the airlines that provide service to Quintana Roo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Quintana Roo. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Southwest, Delta, and Aeromexico from Des Moines to Quintana Roo. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Aeromexico
7.5
Good
1,696 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,926 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Quintana Roo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Quintana Roo?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Quintana Roo.

  • How long is the flight from Des Moines to Quintana Roo?

    A quick flight from Des Moines to Quintana Roo can take about 8h 36m. Delta provides one of the quickest options available for as low as $469. Des Moines and Quintana Roo are separated by a distance of 1504 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Des Moines to Quintana Roo one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $197. However, be on the lookout for offers from Aeromexico and United Airlines, as they are both options that can get you from Des Moines to Quintana Roo for a low price.

  • Can I find deals for flights from Des Moines to Quintana Roo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Quintana Roo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Quintana Roo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Quintana Roo.

  • Can I find deals for business class flights from Des Moines to Quintana Roo?

    Yes. Cheapflights offers flight deals from Des Moines to Quintana Roo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Quintana Roo?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Quintana Roo (average of $360). Flying from Des Moines to Quintana Roo in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Quintana Roo

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Cancún flights
Cedar Rapids to Cancún flights
Omaha to Cancún flights
Des Moines to Cozumel flights
Cedar Rapids to Cozumel flights
Omaha to Cozumel flights
Omaha to Mexico City flights
Omaha to San José del Cabo flights
Cedar Rapids to San José del Cabo flights
Moline to Cancún flights
Omaha to Puerto Vallarta flights
Des Moines to San José del Cabo flights
Des Moines to Puerto Vallarta flights
Moline to San José del Cabo flights
Cedar Rapids to Mexico City flights
Omaha to Guadalajara flights
Des Moines to Mexico City flights
Moline to Cozumel flights
Cedar Rapids to Puerto Vallarta flights
Omaha to León flights
Moline to Puerto Vallarta flights
Des Moines to Mérida flights
Cedar Rapids to León flights
Omaha to Mazatlán flights
Omaha to Ixtapa flights
Des Moines to Guadalajara flights
Des Moines to León flights
Moline to León flights
Omaha to Oaxaca flights
Omaha to Aguascalientes flights
Omaha to Morelia flights
Omaha to Monterrey flights
La Crosse to Mexico City flights
Waterloo to Cancún flights
Moline to Mexico City flights
Moline to Mérida flights
Omaha to Zacatecas flights
Sioux City to Cancún flights
Sioux City to San José del Cabo flights
Moline to Guadalajara flights
Cedar Rapids to Monterrey flights
Omaha to Santiago de Querétaro flights
Cedar Rapids to Guadalajara flights
Des Moines to Santa Maria Huatulco flights
Des Moines to Saltillo flights
Moline to Aguascalientes flights
Des Moines to Morelia flights
Des Moines to Monterrey flights
Omaha to Tuxtla Gutiérrez flights

Top 5 airlines flying from Des Moines to Quintana Roo

Discover the top 5 airlines that operate flights from Des Moines to Quintana Roo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$350Average$500FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$397Average$585FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$439Average$588FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$460Average$690FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$463Average$629FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.