$197+ Cheap flights from Des Moines (DSM) to Quintana Roo
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CUN
Mar 10 — Mar 171
1 adult, Economy
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Find cheap flights from Des Moines to Quintana Roo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Quintana Roo
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Cheapest flights from Des Moines to Quintana RooExplore the most affordable flight options available from Des Moines to Quintana Roo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
Explore the most affordable flight options available from Des Moines to Quintana Roo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
This Priceline deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- CUN
1 stop13h 55m
Frontier
Wed 3/119:53 am
CUN
- DSM
1 stop9h 23m
Frontier
Deal found 2/5![Frontier logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:21 pm
DSM
- CUN
1 stop14h 55m
Frontier
Mon 3/1610:08 am
CUN
- DSM
1 stop9h 08m
Frontier
Deal found 2/7![Frontier logo]()
$374
This Priceline deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:27 pm
DSM
- CUN
1 stop20h 50m
Frontier
Wed 2/182:27 pm
CUN
- DSM
1 stop29h 20m
Frontier
Deal found 2/4![Frontier logo]()
$398
This Frontier deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:00 am
DSM
- CUN
2 stops22h 09m
Frontier
Mon 3/1610:08 am
CUN
- DSM
1 stop9h 08m
Frontier
Deal found 2/7![Frontier logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:20 pm
DSM
- CUN
1 stop24h 19m
Frontier
Thu 5/143:54 pm
CUN
- DSM
1 stop21h 35m
Frontier
Deal found 2/6![Frontier logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:21 pm
DSM
- CUN
2 stops35h 24m
Multiple Airlines
Fri 3/1310:08 am
CUN
- DSM
1 stop9h 08m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- CUN
1 stop13h 55m
Multiple Airlines
Wed 3/1110:10 am
CUN
- DSM
2 stops32h 53m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$435
This Priceline deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- CUN
1 stop13h 55m
Frontier
Sat 3/149:53 am
CUN
- DSM
1 stop9h 23m
Frontier
Deal found 2/5![Frontier logo]()
$436
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:08 pm
DSM
- CUN
1 stop17h 03m
American Airlines
Thu 3/55:20 pm
CUN
- DSM
1 stop7h 39m
American Airlines
Deal found 2/5![American Airlines logo]()
$440
This Travelocity deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:27 pm
DSM
- CUN
2 stops19h 01m
Frontier
Mon 3/912:15 pm
CUN
- DSM
1 stop21h 50m
Frontier
Deal found 2/5![Frontier logo]()
$441
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:00 am
DSM
- CZM
1 stop7h 11m
American Airlines
Tue 3/312:01 pm
CZM
- DSM
1 stop8h 55m
American Airlines
Deal found 2/7![American Airlines logo]()
$447
This SmartFares deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:35 am
DSM
- CZM
1 stop8h 10m
Aeromexico
Tue 3/312:00 pm
CZM
- DSM
1 stop7h 38m
Aeromexico
Deal found 2/8![Aeromexico logo]()
$480
Best flights from Des Moines to Quintana RooDiscover carefully curated flight deals from Des Moines to Quintana Roo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
Discover carefully curated flight deals from Des Moines to Quintana Roo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:21 pm
DSM
- CUN
1 stop14h 55m
Frontier
Mon 3/1610:08 am
CUN
- DSM
1 stop9h 08m
Frontier
Deal found 2/7![Frontier logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:21 pm
DSM
- CUN
2 stops35h 24m
Multiple Airlines
Fri 3/1310:08 am
CUN
- DSM
1 stop9h 08m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:04 pm
DSM
- CUN
1 stop8h 07m
Delta
Wed 2/253:00 pm
CUN
- DSM
1 stop7h 20m
Delta
Deal found 2/5![Delta logo]()
$454
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:05 am
DSM
- CUN
1 stop6h 30m
American Airlines
Fri 5/81:00 pm
CUN
- DSM
1 stop10h 59m
American Airlines
Deal found 2/7![American Airlines logo]()
$466
This Aeromexico deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:24 am
DSM
- CUN
1 stop10h 21m
Aeromexico
Wed 3/48:00 am
CUN
- DSM
1 stop9h 27m
Aeromexico
Deal found 2/4![Aeromexico logo]()
$466
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:04 pm
DSM
- CZM
2 stops20h 19m
United Airlines
Tue 3/313:52 pm
CZM
- DSM
1 stop5h 51m
United Airlines
Deal found 2/8![United Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:01 pm
DSM
- CUN
2 stops36h 32m
Multiple Airlines
Thu 5/143:54 pm
CUN
- DSM
1 stop21h 35m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$466
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:10 am
DSM
- CUN
1 stop6h 54m
Delta
Fri 5/89:55 am
CUN
- DSM
2 stops10h 41m
Delta
Deal found 2/7![Delta logo]()
$470
This Aeromexico deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:35 am
DSM
- CUN
1 stop5h 59m
Aeromexico
Tue 4/78:00 am
CUN
- DSM
1 stop8h 33m
Aeromexico
Deal found 2/8![Aeromexico logo]()
$477
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:33 am
DSM
- CUN
1 stop8h 47m
Delta
Wed 3/2510:50 am
CUN
- DSM
1 stop9h 55m
Delta
Deal found 2/7![Delta logo]()
$488
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:35 am
DSM
- CUN
1 stop7h 25m
Delta
Tue 4/78:00 am
CUN
- DSM
1 stop8h 33m
Delta
Deal found 2/6![Delta logo]()
$488
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:20 am
DSM
- CZM
1 stop9h 22m
United Airlines
Tue 6/23:52 pm
CZM
- DSM
1 stop5h 39m
United Airlines
Deal found 2/8![United Airlines logo]()
$610
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:33 am
DSM
- CUN
2 stops12h 59m
Delta
Wed 4/111:05 am
CUN
- DSM
2 stops11h 33m
Delta
Deal found 2/8![Delta logo]()
$492
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:20 am
DSM
- CZM
1 stop7h 22m
United Airlines
Tue 4/73:52 pm
CZM
- DSM
1 stop5h 51m
United Airlines
Deal found 2/6![United Airlines logo]()
$610
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:55 am
DSM
- CZM
1 stop8h 05m
Delta
Wed 4/82:00 pm
CZM
- DSM
1 stop7h 38m
Delta
Deal found 2/8![Delta logo]()
$500
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:00 am
DSM
- CZM
2 stops29h 23m
United Airlines
Wed 4/13:52 pm
CZM
- DSM
2 stops28h 35m
United Airlines
Deal found 2/8![United Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:47 pm
DSM
- CZM
2 stops19h 58m
Delta
Tue 3/172:00 pm
CZM
- DSM
1 stop7h 38m
Delta
Deal found 2/7![Delta logo]()
$504
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:59 pm
DSM
- CZM
2 stops20h 43m
United Airlines
Wed 4/83:52 pm
CZM
- DSM
1 stop5h 51m
United Airlines
Deal found 2/5![United Airlines logo]()
$614
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:30 am
DSM
- CZM
2 stops10h 12m
United Airlines
Wed 4/223:52 pm
CZM
- DSM
1 stop5h 51m
United Airlines
Deal found 2/5![United Airlines logo]()
$614
Last-minute flights from Des Moines to Quintana RooDiscover last-minute flight deals from Des Moines to Quintana Roo. Data last updated February 8, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Quintana Roo. Data last updated February 8, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:27 pm
DSM
- CUN
1 stop20h 50m
Frontier
Wed 2/182:27 pm
CUN
- DSM
1 stop29h 20m
Frontier
Deal found 2/4![Frontier logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:27 pm
DSM
- CUN
1 stop20h 50m
Multiple Airlines
Wed 2/181:25 pm
CUN
- DSM
2 stops25h 54m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$445
This Aeromexico deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:50 am
DSM
- CZM
1 stop8h 07m
Aeromexico
Thu 2/263:10 pm
CZM
- DSM
1 stop7h 18m
Aeromexico
Deal found 2/7![Aeromexico logo]()
$518
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/183:24 pm
DSM
- CZM
2 stops21h 59m
United Airlines
Wed 2/252:25 pm
CZM
- DSM
1 stop7h 55m
United Airlines
Deal found 2/7![United Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:08 pm
DSM
- CUN
1 stop17h 03m
American Airlines
Thu 3/55:20 pm
CUN
- DSM
1 stop7h 39m
American Airlines
Deal found 2/5![American Airlines logo]()
$440
This Travelocity deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:27 pm
DSM
- CUN
2 stops19h 01m
Frontier
Mon 3/912:15 pm
CUN
- DSM
1 stop21h 50m
Frontier
Deal found 2/5![Frontier logo]()
$441
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:21 pm
DSM
- CUN
2 stops35h 24m
Multiple Airlines
Fri 3/1310:08 am
CUN
- DSM
1 stop9h 08m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$427
This Expedia deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- CUN
1 stop13h 55m
Frontier
Wed 3/119:53 am
CUN
- DSM
1 stop9h 23m
Frontier
Deal found 2/5![Frontier logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- CUN
1 stop13h 55m
Multiple Airlines
Wed 3/1110:10 am
CUN
- DSM
2 stops32h 53m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$435
This Priceline deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:21 pm
DSM
- CUN
1 stop13h 55m
Frontier
Sat 3/149:53 am
CUN
- DSM
1 stop9h 23m
Frontier
Deal found 2/5![Frontier logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:21 pm
DSM
- CUN
1 stop14h 55m
Frontier
Mon 3/1610:08 am
CUN
- DSM
1 stop9h 08m
Frontier
Deal found 2/7![Frontier logo]()
$374
This Frontier deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:00 am
DSM
- CUN
2 stops22h 09m
Frontier
Mon 3/1610:08 am
CUN
- DSM
1 stop9h 08m
Frontier
Deal found 2/7![Frontier logo]()
$421
One-way flights from Des Moines to Quintana RooSearch for one-way flight options from Des Moines to Quintana Roo. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
Search for one-way flight options from Des Moines to Quintana Roo. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:00 am
DSM
- CUN
1 stop7h 24m
American Airlines
Deal found 2/5![American Airlines logo]()
$197
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:24 am
DSM
- CUN
1 stop10h 21m
Delta
Deal found 2/6![Delta logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:21 pm
DSM
- CUN
2 stops36h 32m
Frontier
Deal found 2/6![Frontier logo]()
$214
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:20 am
DSM
- CUN
1 stop6h 50m
United Airlines
Deal found 2/6![United Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:37 pm
DSM
- CUN
1 stop15h 34m
American Airlines
Deal found 2/5![American Airlines logo]()
$230
This Aeromexico deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:24 am
DSM
- CZM
1 stop8h 31m
Aeromexico
Deal found 2/6![Aeromexico logo]()
$233
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:25 pm
DSM
- CUN
2 stops16h 35m
Delta
Deal found 2/6![Delta logo]()
$234
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:24 pm
DSM
- CUN
2 stops21h 10m
United Airlines
Deal found 2/5![United Airlines logo]()
$252
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:55 pm
DSM
- CZM
2 stops18h 28m
United Airlines
Deal found 2/8![United Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:25 pm
DSM
- CUN
3 stops41h 36m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/148:21 pm
DSM
- CUN
2 stops38h 21m
Frontier
Deal found 2/6![Frontier logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/148:21 pm
DSM
- CUN
3 stops37h 35m
Multiple Airlines
Deal found 2/6![Multiple Airlines logo]()
$311
Find flight deals from Des Moines to Quintana Roo
Keep the following information in mind while searching for Des Moines to Quintana Roo flight deals. Data was last updated February 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $362 (Expedia) |
One-way from | $197 (American Airlines) |
Popular in | June |
Cheapest in | September |
Average price | $619 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Quintana Roo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Des Moines to Quintana Roo that are best for you.
Fly from
Des Moines
Fly to
Quintana Roo
Route
Depart
Return
Price
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 3/9
8:21 pm-11:16 am
1 stop14h 55m
Cancun
Mon 3/16
10:08 am-7:16 pm
1 stop9h 08m
$381
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 3/6
8:21 pm-8:45 am
2 stops35h 24m
Cancun
Fri 3/13
10:08 am-7:16 pm
1 stop9h 08m
$427
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Wed 2/18
12:04 pm-9:11 pm
1 stop8h 07m
Cancun
Wed 2/25
3:00 pm-9:20 pm
1 stop7h 20m
$454
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sun 5/3
7:05 am-1:35 pm
1 stop6h 30m
Cancun
Fri 5/8
1:00 pm-11:59 pm
1 stop10h 59m
$466
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 3/2
5:24 am-4:45 pm
1 stop10h 21m
Cancun
Wed 3/4
8:00 am-4:27 pm
1 stop9h 27m
$466
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 5/8
10:01 pm-10:33 am
2 stops36h 32m
Cancun
Thu 5/14
3:54 pm-1:29 pm
1 stop21h 35m
$466
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 5/4
6:10 am-1:04 pm
1 stop6h 54m
Cancun
Fri 5/8
9:55 am-8:36 pm
2 stops10h 41m
$470
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Tue 3/31
5:35 am-11:34 am
1 stop5h 59m
Cancun
Tue 4/7
8:00 am-4:33 pm
1 stop8h 33m
$477
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Wed 3/18
11:33 am-8:20 pm
1 stop8h 47m
Cancun
Wed 3/25
10:50 am-8:45 pm
1 stop9h 55m
$488
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Tue 3/31
5:35 am-1:00 pm
1 stop7h 25m
Cancun
Tue 4/7
8:00 am-4:33 pm
1 stop8h 33m
$488
Showing 1-10 of 33 results
Best time to book a flight from Des Moines to Quintana Roo
Have a flexible travel schedule? Discover the best time to fly to Quintana Roo from Des Moines with our price prediction graph.
DSM-CUN
DSM-CZM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Quintana Roo
DSM-MXQR
DSM-CUN
DSM-CZM
What is the cheapest month to book a flight from Des Moines to Quintana Roo?
Currently, April is the cheapest month in which you can book a flight from Des Moines to Quintana Roo (average of $321). Flying from Des Moines to Quintana Roo in August is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Quintana Roo?
Reviews of airlines servicing Quintana Roo
Get insights into the airlines that provide service to Quintana Roo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Quintana Roo. Reviews last updated February 8, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Quintana Roo. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Quintana Roo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Quintana Roo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Quintana Roo by cabin class
Find flights from Des Moines to Quintana Roo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Quintana Roo flights
Browse other Des Moines and Quintana Roo flight options. Last updated on February 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Des Moines to Quintana Roo
Discover the top 5 airlines that operate flights from Des Moines to Quintana Roo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$249 | Average$505 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$398 | Average$599 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$438 | Average$574 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$457 | Average$596 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$569 | Average$690 | FlexibilityNo cancel fee | On-time63% |