$156+ Cheap flights from Des Moines (DSM) to Puerto Rico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJU
Apr 25 — May 21
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Puerto Rico with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to Puerto RicoExplore the most affordable flight options available from Des Moines to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from Des Moines to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:00 am
DSM
- SJU
1 stop11h 19m
Multiple Airlines
Thu 4/96:00 am
SJU
- DSM
1 stop8h 46m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:26 am
DSM
- SJU
1 stop12h 32m
Multiple Airlines
Wed 4/11:11 pm
SJU
- DSM
2 stops25h 35m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:37 pm
DSM
- SJU
2 stops15h 27m
Multiple Airlines
Mon 6/86:00 am
SJU
- DSM
1 stop18h 27m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$392
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:00 am
DSM
- SJU
2 stops36h 19m
Multiple Airlines
Thu 4/96:00 am
SJU
- DSM
1 stop8h 46m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:41 pm
DSM
- SJU
1 stop10h 20m
Multiple Airlines
Tue 5/266:41 pm
SJU
- DSM
2 stops52h 50m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:16 pm
DSM
- SJU
2 stops13h 33m
Multiple Airlines
Mon 6/86:00 am
SJU
- DSM
1 stop18h 27m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:36 pm
DSM
- SJU
1 stop27h 19m
Multiple Airlines
Tue 4/1412:55 pm
SJU
- DSM
2 stops49h 51m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
DSM
- SJU
1 stop11h 55m
Multiple Airlines
Thu 4/212:55 pm
SJU
- DSM
1 stop10h 56m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$410
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:37 pm
DSM
- SJU
1 stop11h 24m
Multiple Airlines
Tue 6/96:41 pm
SJU
- DSM
2 stops19h 50m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:07 pm
DSM
- SJU
1 stop22h 51m
Multiple Airlines
Sat 6/134:05 pm
SJU
- DSM
2 stops31h 47m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:00 am
DSM
- BQN
2 stops14h 09m
United Airlines
Tue 10/612:15 am
BQN
- DSM
2 stops13h 15m
United Airlines
Deal found 3/24![United Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:02 am
DSM
- BQN
2 stops12h 07m
United Airlines
Thu 5/712:15 am
BQN
- DSM
2 stops11h 22m
United Airlines
Deal found 3/23![United Airlines logo]()
$676
Best flights from Des Moines to Puerto RicoDiscover carefully curated flight deals from Des Moines to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from Des Moines to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/272:44 pm
DSM
- SJU
1 stop7h 29m
Delta
Tue 5/57:15 am
SJU
- DSM
2 stops14h 24m
Delta
Deal found 3/24![Delta logo]()
$456
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:23 am
DSM
- BQN
2 stops10h 46m
United Airlines
Tue 9/2212:15 am
BQN
- DSM
2 stops13h 04m
United Airlines
Deal found 3/24![United Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/262:44 pm
DSM
- SJU
1 stop7h 29m
Delta
Tue 5/52:03 pm
SJU
- DSM
1 stop7h 36m
Delta
Deal found 3/25![Delta logo]()
$456
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:44 pm
DSM
- SJU
1 stop7h 28m
Delta
Fri 4/246:15 am
SJU
- DSM
1 stop8h 40m
Delta
Deal found 3/21![Delta logo]()
$456
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:56 am
DSM
- SJU
2 stops8h 30m
Delta
Tue 5/127:05 am
SJU
- DSM
2 stops10h 43m
Delta
Deal found 3/25![Delta logo]()
$456
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:51 am
DSM
- SJU
1 stop10h 24m
Delta
Mon 5/112:48 pm
SJU
- DSM
1 stop8h 44m
Delta
Deal found 3/26![Delta logo]()
$456
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:44 pm
DSM
- SJU
1 stop7h 28m
Delta
Tue 4/286:15 am
SJU
- DSM
1 stop8h 40m
Delta
Deal found 3/21![Delta logo]()
$456
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:00 am
DSM
- BQN
2 stops14h 09m
United Airlines
Thu 5/712:15 am
BQN
- DSM
2 stops15h 09m
United Airlines
Deal found 3/22![United Airlines logo]()
$676
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:45 am
DSM
- SJU
1 stop6h 31m
Delta
Tue 9/297:30 am
SJU
- DSM
2 stops14h 15m
Delta
Deal found 3/22![Delta logo]()
$466
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:00 am
DSM
- BQN
2 stops17h 09m
United Airlines
Tue 5/1212:15 am
BQN
- DSM
2 stops11h 22m
United Airlines
Deal found 3/21![United Airlines logo]()
$726
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:30 pm
DSM
- BQN
2 stops25h 39m
United Airlines
Fri 9/2512:15 am
BQN
- DSM
2 stops13h 15m
United Airlines
Deal found 3/23![United Airlines logo]()
$749
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/203:24 pm
DSM
- BQN
2 stops30h 45m
United Airlines
Sat 9/2612:15 am
BQN
- DSM
2 stops11h 05m
United Airlines
Deal found 3/23![United Airlines logo]()
$749
Last-minute flights from Des Moines to Puerto RicoDiscover last-minute flight deals from Des Moines to Puerto Rico. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Puerto Rico. Data last updated March 26, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
DSM
- SJU
1 stop11h 55m
Multiple Airlines
Thu 4/212:55 pm
SJU
- DSM
1 stop10h 56m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$410
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:26 am
DSM
- SJU
1 stop12h 32m
Multiple Airlines
Wed 4/11:11 pm
SJU
- DSM
2 stops25h 35m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:00 am
DSM
- SJU
2 stops36h 19m
Multiple Airlines
Thu 4/96:00 am
SJU
- DSM
1 stop8h 46m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:00 am
DSM
- SJU
1 stop11h 19m
Multiple Airlines
Thu 4/96:00 am
SJU
- DSM
1 stop8h 46m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:36 pm
DSM
- SJU
1 stop27h 19m
Multiple Airlines
Tue 4/1412:55 pm
SJU
- DSM
2 stops49h 51m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:51 am
DSM
- SJU
1 stop7h 33m
Delta
Fri 4/242:03 pm
SJU
- DSM
1 stop7h 46m
Delta
Deal found 3/25![Delta logo]()
$456
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
DSM
- SJU
2 stops13h 51m
American Airlines
Tue 4/2811:43 am
SJU
- DSM
2 stops13h 06m
American Airlines
Deal found 3/22![American Airlines logo]()
$471
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:33 pm
DSM
- SJU
1 stop13h 27m
Multiple Airlines
Sun 4/262:59 am
SJU
- DSM
2 stops20h 43m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/262:44 pm
DSM
- SJU
1 stop7h 29m
Delta
Tue 5/56:15 am
SJU
- DSM
2 stops15h 24m
Delta
Deal found 3/23![Delta logo]()
$461
One-way flights from Des Moines to Puerto RicoSearch for one-way flight options from Des Moines to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from Des Moines to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:33 pm
DSM
- SJU
1 stop18h 28m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- SJU
2 stops25h 27m
Frontier
Deal found 3/25![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:07 pm
DSM
- SJU
1 stop20h 51m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:14 pm
DSM
- SJU
2 stops12h 04m
Frontier
Deal found 3/24![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:00 am
DSM
- SJU
2 stops42h 01m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:55 pm
DSM
- SJU
1 stop24h 46m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:57 pm
DSM
- SJU
1 stop31h 41m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:41 pm
DSM
- SJU
1 stop31h 16m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$217
Find flight deals from Des Moines to Puerto Rico
Keep the following information in mind while searching for Des Moines to Puerto Rico flight deals. Data was last updated March 26, 2026.
Round-trip from | $313 (Kiwi.com) |
|---|---|
One-way from | $156 (Kiwi.com) |
Popular in | December |
Cheapest in | May |
Average price | $656 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Puerto Rico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Des Moines to Puerto Rico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Mon 4/27
2:44 pm-11:13 pm
1 stop7h 29m
San Juan Luis Munoz Marin Intl
Tue 5/5
7:15 am-8:39 pm
2 stops14h 24m
$456
Quickest round-trip
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Sun 4/26
2:44 pm-11:13 pm
1 stop7h 29m
San Juan Luis Munoz Marin Intl
Tue 5/5
2:03 pm-8:39 pm
1 stop7h 36m
$456
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Mon 4/13
2:44 pm-11:12 pm
1 stop7h 28m
San Juan Luis Munoz Marin Intl
Fri 4/24
6:15 am-1:55 pm
1 stop8h 40m
$456
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Wed 5/6
10:56 am-8:26 pm
2 stops8h 30m
San Juan Luis Munoz Marin Intl
Tue 5/12
7:05 am-4:48 pm
2 stops10h 43m
$456
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Wed 5/6
11:51 am-11:15 pm
1 stop10h 24m
San Juan Luis Munoz Marin Intl
Mon 5/11
2:48 pm-10:32 pm
1 stop8h 44m
$456
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Mon 4/13
2:44 pm-11:12 pm
1 stop7h 28m
San Juan Luis Munoz Marin Intl
Tue 4/28
6:15 am-1:55 pm
1 stop8h 40m
$456
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Tue 9/22
5:45 am-1:16 pm
1 stop6h 31m
San Juan Luis Munoz Marin Intl
Tue 9/29
7:30 am-8:45 pm
2 stops14h 15m
$466
Des MoinesAguadilla
DSM - BQN
DSMBQN
Des Moines
Sat 9/19
11:23 am-11:09 pm
2 stops10h 46m
Aguadilla Borinquen
Tue 9/22
12:15 am-12:19 pm
2 stops13h 04m
$576
Des MoinesAguadilla
DSM - BQN
DSMBQN
Des Moines
Mon 5/4
8:00 am-11:09 pm
2 stops14h 09m
Aguadilla Borinquen
Thu 5/7
12:15 am-2:24 pm
2 stops15h 09m
$676
Des MoinesAguadilla
DSM - BQN
DSMBQN
Des Moines
Mon 5/11
5:00 am-11:09 pm
2 stops17h 09m
Aguadilla Borinquen
Tue 5/12
12:15 am-10:37 am
2 stops11h 22m
$726
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Puerto Rico
Have a flexible travel schedule? Discover the best time to fly to Puerto Rico from Des Moines with our price prediction graph.
DSM-SJU
DSM-BQN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Puerto Rico
DSM-PR0
DSM-SJU
DSM-BQN
What is the cheapest month to book a flight from Des Moines to Puerto Rico?
Currently, March is the cheapest month in which you can book a flight from Des Moines to Puerto Rico (average of $363). Flying from Des Moines to Puerto Rico in December is currently the most expensive (average of $507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Puerto Rico
Get insights into the airlines that provide service to Puerto Rico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Puerto Rico. Reviews last updated March 26, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Puerto Rico to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Puerto Rico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Puerto Rico
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Complete your trip
Complete your trip to Puerto Rico by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Puerto Rico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Puerto Rico flights
Browse other Des Moines and Puerto Rico flight options. Last updated on March 26, 2026.
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Top 4 airlines flying from Des Moines to Puerto Rico
Discover the top 4 airlines that operate flights from Des Moines to Puerto Rico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$395 | Average$656 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$396 | Average$552 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$401 | Average$771 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$401 | Average$555 | FlexibilityNo cancel fee | On-time69% |