Panama

$517+ Cheap flights from Syracuse (SYR) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Sep 5 — Sep 121
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Cheap flight deals from Syracuse to Panama

Keep the following information in mind while searching for Syracuse to Panama flight deals. Data was last updated August 31, 2025.

Round-trip from

$517
(Delta)

Popular in

December

Cheapest in

November

Average price

$623
From Syracuse Hancock Intl to Panama
Highest demand for flights based on searches. 4% potential increase in price ($33 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Average for round-trip flights in August 2025

Find flight deals from Syracuse to Panama

Cheapest flights from Syracuse to Panama
Explore the most affordable flight options available from Syracuse to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 31, 2025.

This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/155:55 amSYR - PTY
1 stop8h 00mDelta
Thu 10/22:10 pmPTY - SYR
1 stop8h 49mDelta
Deal found 8/29$517
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:00 amSYR - PTY
1 stop8h 50mUnited Airlines
Wed 9/179:45 amPTY - SYR
2 stops22h 58mUnited Airlines
Deal found 8/30$522
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:45 pmSYR - PTY
2 stops19h 29mUnited Airlines
Mon 10/2010:00 amPTY - SYR
2 stops22h 44mUnited Airlines
Deal found 8/29$549
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:26 pmSYR - PTY
2 stops20h 27mAmerican Airlines
Fri 1/92:45 pmPTY - SYR
2 stops20h 52mAmerican Airlines
Deal found 8/29$702
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2512:23 pmSYR - PTY
2 stops25h 15mAmerican Airlines
Sun 11/302:43 pmPTY - SYR
2 stops22h 09mAmerican Airlines
Deal found 8/31$741
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:11 amSYR - PTY
1 stop10h 43mAmerican Airlines
Thu 1/14:56 pmPTY - SYR
2 stops19h 57mAmerican Airlines
Deal found 8/31$956
This Mytrip deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:00 pmSYR - PTY
3 stops38h 20mMultiple Airlines
Sun 11/302:55 pmPTY - SYR
2 stops28h 43mMultiple Airlines
Deal found 8/31$1,063

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 31, 2025.
Use the filters below to find and compare flights from Syracuse to Panama that are best for you.

Fly from

Syracuse

Fly to

Panama

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 9/15

5:55 am-12:55 pm

1 stop8h 00m

Panama City Tocumen Intl

Thu 10/2

2:10 pm-11:59 pm

1 stop8h 49m

$517

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 10/13

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Mon 10/20

10:00 am-11:58 am

2 stops24h 58m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 9/10

6:47 pm-2:31 pm

2 stops20h 44m

Panama City Tocumen Intl

Wed 9/17

1:45 pm-4:38 pm

2 stops25h 53m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 9/15

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Thu 10/2

9:45 am-10:22 am

2 stops23h 37m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 9/10

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Wed 9/17

9:45 am-9:43 am

2 stops22h 58m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 12/18

5:26 pm-1:53 pm

2 stops20h 27m

Panama City Tocumen Intl

Fri 1/9

2:45 pm-11:37 am

2 stops20h 52m

$702

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 2/16

4:38 pm-1:10 pm

2 stops20h 32m

Panama City Tocumen Intl

Sun 2/22

4:40 pm-10:42 am

2 stops18h 02m

$715

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Tue 11/25

12:23 pm-1:38 pm

2 stops25h 15m

Panama City Tocumen Intl

Sun 11/30

2:43 pm-12:52 pm

2 stops22h 09m

$741

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/29

Best time to book a flight from Syracuse to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama

What is the cheapest month to book a flight from Syracuse to Panama?

Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama (average of $478). Flying from Syracuse to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 31, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Syracuse to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
8.0
Very good
8.0
Very good

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
8.0
Very good

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Syracuse to Panama?

    If you book a flight to Panama from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Panama?

    For as low as $517, Delta can have you in Panama from Syracuse in 8h. Syracuse and Panama are separated by a distance of 2359 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Syracuse to Panama that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama.

  • Can I find deals for business class flights from Syracuse to Panama?

    Yes. Cheapflights offers flight deals from Syracuse to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama?

    Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama (average of $478). Flying from Syracuse to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Syracuse to Panama

Discover the top 2 airlines that operate flights from Syracuse to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$310Average$611FlexibilityNo cancel feeOn-time69%
DeltaCheapest$491Average$551FlexibilityNo cancel feeOn-timeN/A

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