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$226+ Cheap flights from Syracuse (SYR) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from Syracuse to Panama

Keep the following information in mind while searching for Syracuse to Panama flight deals. Data was last updated July 1, 2025.

Round-trip from

$522
(United Airlines)

One-way from

$226
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$692
From Syracuse Hancock Intl to Panama
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One-way flight from Syracuse Hancock Intl to Panama
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Highest demand for flights based on searches. 10% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Syracuse to Panama

Cheapest flights from Syracuse to Panama
Explore the most affordable flight options available from Syracuse to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/137:45 pmSYR - PTY
2 stops23h 52mUnited Airlines
Wed 8/209:45 amPTY - SYR
2 stops12h 54mUnited Airlines
Deal found 6/28$522
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/56:00 amSYR - PTY
2 stops9h 15mAmerican Airlines
Wed 7/91:55 pmPTY - SYR
2 stops20h 42mAmerican Airlines
Deal found 7/1$677
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:55 amSYR - PTY
1 stop8h 24mMultiple Airlines
Wed 12/3112:03 pmPTY - SYR
1 stop28h 02mMultiple Airlines
Deal found 6/30$1,686
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amSYR - PTY
1 stop7h 52mDelta
Wed 12/318:10 amPTY - SYR
1 stop14h 15mDelta
Deal found 6/30$2,065

Cheapflights Fare Finder

Customize your flight search to find flights from Syracuse to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Syracuse to Panama that are best for you.

Fly from

Syracuse

Fly to

Panama

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 8/13

7:45 pm-6:37 pm

2 stops23h 52m

Panama City Tocumen Intl

Wed 8/20

9:45 am-11:39 pm

2 stops12h 54m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Fri 12/19

5:46 am-3:20 pm

1 stop9h 34m

Panama City Tocumen Intl

Wed 12/31

4:45 pm-4:02 pm

2 stops23h 17m

$894

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 12/20

11:55 am-8:19 pm

1 stop8h 24m

Panama City Tocumen Intl

Wed 12/31

12:03 pm-4:05 pm

1 stop28h 02m

$1,686

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 12/18

6:00 am-1:52 pm

1 stop7h 52m

Panama City Tocumen Intl

Wed 12/31

8:10 am-10:25 pm

1 stop14h 15m

$2,065

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 8/6

6:09 am-6:37 pm

2 stops13h 28m

$226

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 8/6

4:47 pm-2:30 pm

2 stops22h 43m

$232

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 8/6

5:50 am-1:13 pm

1 stop8h 23m

$253

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 8/6

8:24 pm-4:30 pm

3 stops45h 06m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/28

Best time to book a flight from Syracuse to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama

What is the cheapest month to book a flight from Syracuse to Panama?

Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama (average of $478). Flying from Syracuse to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 1, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Syracuse to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Panama?

    If you book a flight to Panama from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • What are the cheapest airlines to fly from Syracuse to Panama one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $226. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Syracuse to Panama for a low price.

  • Can I find deals for flights from Syracuse to Panama that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama.

  • Can I find deals for business class flights from Syracuse to Panama?

    Yes. Cheapflights offers flight deals from Syracuse to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama?

    Currently, October is the cheapest month in which you can book a flight from Syracuse to Panama (average of $478). Flying from Syracuse to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Syracuse to Panama

Discover the top 2 airlines that operate flights from Syracuse to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$415Average$551FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$440Average$585FlexibilityNo cancel feeOn-time69%

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