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Panama

$226+ Cheap flights from Syracuse (SYR) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PTY
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from Syracuse to Panama

Cheapest flights from Syracuse to Panama
Explore the most affordable flight options available from Syracuse to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:49 amSYR - PTY
1 stop9h 13mUnited Airlines
Thu 12/1111:55 pmPTY - SYR
1 stop9h 59mUnited Airlines
Deal found 11/2$518
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amSYR - PTY
1 stop14h 00mDelta
Wed 1/143:20 pmPTY - SYR
1 stop8h 39mDelta
Deal found 11/2$606
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:55 pmSYR - PTY
3 stops26h 45mMultiple Airlines
Wed 12/102:55 amPTY - SYR
3 stops18h 10mMultiple Airlines
Deal found 11/2$754
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:19 amSYR - PTY
2 stops24h 11mMultiple Airlines
Wed 1/149:45 amPTY - SYR
3 stops32h 16mMultiple Airlines
Deal found 11/2$2,288

Cheap flight deals from Syracuse to Panama

Keep the following information in mind while searching for Syracuse to Panama flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$518
(United Airlines)

One-way from

$283
(American Airlines)

Popular in

December

Cheapest in

November

Average price

$507
Provider with most accurate pricing for Syracuse Hancock Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Panama City Tocumen Intl flights.
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From Syracuse Hancock Intl to Panama
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One-way flight from Syracuse Hancock Intl to Panama
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Highest demand for flights based on searches. 12% potential increase in price ($85 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Syracuse to Panama that are best for you.

Fly from

Syracuse

Fly to

Panama

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 12/4

10:49 am-8:02 pm

1 stop9h 13m

Panama City Tocumen Intl

Thu 12/11

11:55 pm-9:54 am

1 stop9h 59m

$518

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 1/10

3:03 pm-1:27 pm

2 stops22h 24m

Panama City Tocumen Intl

Sat 1/17

2:27 pm-11:26 am

2 stops20h 59m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 12/31

5:29 pm-1:53 pm

2 stops20h 24m

Panama City Tocumen Intl

Wed 1/14

2:27 pm-11:26 am

2 stops20h 59m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 12/31

6:00 am-8:00 pm

1 stop14h 00m

Panama City Tocumen Intl

Wed 1/14

3:20 pm-11:59 pm

1 stop8h 39m

$606

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 1/5

5:30 am-1:53 pm

1 stop8h 23m

Panama City Tocumen Intl

Thu 1/15

4:50 pm-12:00 pm

2 stops19h 10m

$611

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 1/5

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 1/15

3:20 pm-11:59 pm

1 stop8h 39m

$665

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 12/4

10:15 am-8:19 pm

1 stop10h 04m

Panama City Tocumen Intl

Wed 12/10

2:55 am-7:18 pm

2 stops16h 23m

$828

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 12/31

7:00 am-8:00 pm

2 stops13h 00m

$226

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 12/1

6:00 am-1:55 pm

1 stop7h 55m

$226

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 3/14

6:00 pm-2:20 pm

2 stops21h 20m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 12 results
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Best time to book a flight from Syracuse to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Panama

What is the cheapest month to book a flight from Syracuse to Panama?

Currently, May is the cheapest month in which you can book a flight from Syracuse to Panama (average of $240). Flying from Syracuse to Panama in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 3, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Syracuse to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Panama?

    If you book a flight to Panama from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse.

  • How long is the flight from Syracuse to Panama?

    For as low as $518, United Airlines can have you in Panama from Syracuse in 9h 13m. Syracuse and Panama are separated by a distance of 2359 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Syracuse to Panama one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $226. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Syracuse to Panama for a low price.

  • Can I find deals for flights from Syracuse to Panama that include hotel bookings?

    Yes. In addition to deals on Syracuse to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Panama.

  • Can I find deals for business class flights from Syracuse to Panama?

    Yes. Cheapflights offers flight deals from Syracuse to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Panama?

    Currently, May is the cheapest month in which you can book a flight from Syracuse to Panama (average of $240). Flying from Syracuse to Panama in December is currently the most expensive (average of $646). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Syracuse to Panama

Discover the top 2 airlines that operate flights from Syracuse to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$490Average$611FlexibilityNo cancel feeOn-time69%
DeltaCheapest$491Average$551FlexibilityNo cancel feeOn-timeN/A

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