$285+ Cheap flights from San Antonio (SAT) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
Apr 8 — Apr 151
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Antonio to PanamaExplore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 9, 2026.
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 9, 2026.
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:25 pm
SAT
- PTY
2 stops11h 30m
Multiple Airlines
Wed 5/275:30 am
PTY
- SAT
2 stops10h 09m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$521
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Fri 4/245:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$530
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Fri 4/245:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 am
SAT
- PTY
1 stop8h 44m
United Airlines
Thu 5/77:55 am
PTY
- SAT
1 stop13h 25m
United Airlines
Deal found 3/5![United Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:30 am
SAT
- PTY
1 stop8h 44m
United Airlines
Thu 6/183:30 pm
PTY
- SAT
1 stop7h 12m
United Airlines
Deal found 3/5![United Airlines logo]()
$571
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:00 am
SAT
- PTY
1 stop9h 54m
American Airlines
Tue 1/122:27 pm
PTY
- SAT
2 stops18h 55m
American Airlines
Deal found 3/6![American Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:19 pm
SAT
- PTY
2 stops23h 27m
American Airlines
Thu 5/71:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Deal found 3/9![American Airlines logo]()
$577
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:57 pm
SAT
- PTY
1 stop24h 40m
United Airlines
Thu 7/167:55 am
PTY
- SAT
1 stop7h 44m
United Airlines
Deal found 3/5![United Airlines logo]()
$578
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:06 am
SAT
- PTY
1 stop9h 14m
American Airlines
Thu 9/103:40 pm
PTY
- SAT
2 stops20h 26m
American Airlines
Deal found 3/7![American Airlines logo]()
$582
Best flights from San Antonio to PanamaDiscover carefully curated flight deals from San Antonio to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 9, 2026.
Discover carefully curated flight deals from San Antonio to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 9, 2026.
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:35 am
SAT
- PTY
1 stop11h 02m
United Airlines
Thu 9/1010:00 am
PTY
- SAT
1 stop9h 53m
United Airlines
Deal found 3/7![United Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:25 am
SAT
- PTY
1 stop7h 25m
Delta
Mon 6/12:15 pm
PTY
- SAT
1 stop8h 16m
Delta
Deal found 3/9![Delta logo]()
$571
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:35 am
SAT
- PTY
1 stop8h 37m
United Airlines
Wed 5/137:55 am
PTY
- SAT
1 stop13h 25m
United Airlines
Deal found 3/8![United Airlines logo]()
$571
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:30 am
SAT
- PTY
1 stop13h 07m
United Airlines
Thu 7/210:00 am
PTY
- SAT
1 stop11h 13m
United Airlines
Deal found 3/4![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 am
SAT
- PTY
1 stop13h 07m
United Airlines
Fri 5/17:55 am
PTY
- SAT
1 stop7h 44m
United Airlines
Deal found 3/4![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:40 am
SAT
- PTY
1 stop6h 32m
United Airlines
Mon 4/277:55 am
PTY
- SAT
1 stop15h 04m
United Airlines
Deal found 3/6![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:30 am
SAT
- PTY
1 stop13h 07m
United Airlines
Wed 7/153:30 pm
PTY
- SAT
1 stop16h 57m
United Airlines
Deal found 3/4![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:37 am
SAT
- PTY
1 stop28h 37m
United Airlines
Sun 8/233:30 pm
PTY
- SAT
1 stop7h 08m
United Airlines
Deal found 3/8![United Airlines logo]()
$598
Last-minute flights from San Antonio to PanamaDiscover last-minute flight deals from San Antonio to Panama. Data last updated March 9, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Panama. Data last updated March 9, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Wed 4/225:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$521
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Fri 4/245:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$559
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Fri 4/245:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$530
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 am
SAT
- PTY
1 stop8h 44m
United Airlines
Thu 5/77:55 am
PTY
- SAT
1 stop13h 25m
United Airlines
Deal found 3/5![United Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:20 am
SAT
- PTY
1 stop7h 42m
Delta
Thu 5/72:15 pm
PTY
- SAT
1 stop8h 16m
Delta
Deal found 3/9![Delta logo]()
$571
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:19 pm
SAT
- PTY
2 stops23h 27m
American Airlines
Thu 5/71:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Deal found 3/9![American Airlines logo]()
$577
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 am
SAT
- PTY
1 stop13h 07m
United Airlines
Fri 5/17:55 am
PTY
- SAT
1 stop7h 44m
United Airlines
Deal found 3/4![United Airlines logo]()
$591
One-way flights from San Antonio to PanamaSearch for one-way flight options from San Antonio to Panama. Find affordable one-way fares based on user searches. Data last updated March 9, 2026.
Search for one-way flight options from San Antonio to Panama. Find affordable one-way fares based on user searches. Data last updated March 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2810:22 am
SAT
- PTY
2 stops38h 43m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:37 pm
SAT
- PTY
2 stops17h 23m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:10 am
SAT
- PTY
1 stop7h 53m
Delta
Deal found 3/4![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:52 pm
SAT
- PTY
1 stop21h 15m
United Airlines
Deal found 3/5![United Airlines logo]()
$336
This WestJet deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:35 am
SAT
- PTY
2 stops48h 45m
WestJet
Deal found 3/5![WestJet logo]()
$2,419
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:52 am
SAT
- PTY
2 stops10h 35m
United Airlines
Deal found 3/6![United Airlines logo]()
$2,434
Find flight deals from San Antonio to Panama
Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated March 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $521 (Avianca) |
One-way from | $285 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $660 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 9, 2026.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Tue 9/1
7:35 am-6:37 pm
1 stop11h 02m
Panama City Tocumen Intl
Thu 9/10
10:00 am-7:53 pm
1 stop9h 53m
$562
Quickest round-trip
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 5/18
5:25 am-12:50 pm
1 stop7h 25m
Panama City Tocumen Intl
Mon 6/1
2:15 pm-10:31 pm
1 stop8h 16m
$571
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 5/11
7:35 am-4:12 pm
1 stop8h 37m
Panama City Tocumen Intl
Wed 5/13
7:55 am-9:20 pm
1 stop13h 25m
$571
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Fri 6/26
5:30 am-6:37 pm
1 stop13h 07m
Panama City Tocumen Intl
Thu 7/2
10:00 am-9:13 pm
1 stop11h 13m
$591
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Tue 4/28
5:30 am-6:37 pm
1 stop13h 07m
Panama City Tocumen Intl
Fri 5/1
7:55 am-3:39 pm
1 stop7h 44m
$591
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 4/20
9:40 am-4:12 pm
1 stop6h 32m
Panama City Tocumen Intl
Mon 4/27
7:55 am-10:59 pm
1 stop15h 04m
$591
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Sun 7/5
5:30 am-6:37 pm
1 stop13h 07m
Panama City Tocumen Intl
Wed 7/15
3:30 pm-8:27 am
1 stop16h 57m
$591
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Sun 8/16
9:37 am-2:14 pm
1 stop28h 37m
Panama City Tocumen Intl
Sun 8/23
3:30 pm-10:38 pm
1 stop7h 08m
$598
Cheapest one-way
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Sat 3/28
10:22 am-1:05 am
2 stops38h 43m
$285
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Sat 3/28
5:10 am-1:03 pm
1 stop7h 53m
$313
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from San Antonio to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
SAT-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Panama
SAT-PA0
SAT-PTY
What is the cheapest month to book a flight from San Antonio to Panama?
Currently, February is the cheapest month in which you can book a flight from San Antonio to Panama (average of $237). Flying from San Antonio to Panama in December is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 9, 2026.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Overall
7.4
Food
6.6
Crew
8.1
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Entertainment
7.1
Overall
7.4
Food
6.6
Crew
8.1
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Entertainment
7.1
Overall
7.4
Food
6.6
Crew
8.1
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
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San Antonio and Panama flights
Browse other San Antonio and Panama flight options. Last updated on March 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from San Antonio to Panama
Discover the top 2 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$467 | Average$779 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$469 | Average$605 | FlexibilityNo cancel fee | On-time69% |