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$187+ Cheap flights from San Antonio (SAT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from San Antonio to Panama

Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(United Airlines)

One-way from

$187
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$582
Provider with most accurate pricing for San Antonio-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for San Antonio-Panama City Tocumen Intl flights.
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From San Antonio to Panama
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One-way flight from San Antonio to Panama
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Highest demand for flights based on searches. 8% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from San Antonio to Panama

Cheapest flights from San Antonio to Panama
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:47 amSAT - PTY
1 stop5h 58mUnited Airlines
Mon 12/294:41 pmPTY - SAT
1 stop17h 09mUnited Airlines
Deal found 11/11$540
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:47 amSAT - PTY
1 stop8h 20mUnited Airlines
Thu 12/1111:35 amPTY - SAT
1 stop7h 12mUnited Airlines
Deal found 11/13$560
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:39 pmSAT - PTY
2 stops19h 08mAmerican Airlines
Thu 12/112:50 pmPTY - SAT
2 stops18h 32mAmerican Airlines
Deal found 11/13$564
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:30 pmSAT - PTY
1 stop20h 37mUnited Airlines
Sat 12/274:41 pmPTY - SAT
1 stop7h 07mUnited Airlines
Deal found 11/12$566
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:10 amSAT - PTY
1 stop8h 11mDelta
Fri 12/123:46 pmPTY - SAT
1 stop8h 31mDelta
Deal found 11/12$580
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:55 amSAT - PTY
1 stop8h 43mUnited Airlines
Sat 12/68:55 amPTY - SAT
1 stop7h 35mUnited Airlines
Deal found 11/13$600
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:20 amSAT - PTY
1 stop9h 22mAmerican Airlines
Sat 12/64:43 pmPTY - SAT
2 stops17h 51mAmerican Airlines
Deal found 11/13$604
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:23 amSAT - PTY
1 stop7h 26mAmerican Airlines
Wed 11/262:43 pmPTY - SAT
1 stop10h 16mAmerican Airlines
Deal found 11/12$636
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:15 amSAT - PTY
1 stop7h 57mDelta
Mon 11/243:37 pmPTY - SAT
1 stop10h 01mDelta
Deal found 11/13$646
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:30 pmSAT - PTY
1 stop20h 37mUnited Airlines
Sat 1/104:41 pmPTY - SAT
1 stop17h 00mUnited Airlines
Deal found 11/12$648
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:00 pmSAT - PTY
2 stops21h 49mAmerican Airlines
Wed 11/192:49 pmPTY - SAT
1 stop10h 10mAmerican Airlines
Deal found 11/11$650

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.

Fly from

San Antonio

Fly to

Panama

Route

Depart

Return

Price

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 3/9

5:00 am-6:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Wed 3/18

3:41 pm-8:53 am

1 stop17h 12m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 4/6

5:30 am-12:55 pm

1 stop7h 25m

Panama City Tocumen Intl

Thu 4/9

2:20 pm-12:14 am

1 stop9h 54m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Thu 3/5

5:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Mon 3/16

3:41 pm-8:53 am

1 stop17h 12m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Fri 2/13

7:40 am-5:07 pm

1 stop8h 27m

Panama City Tocumen Intl

Wed 2/18

4:41 pm-8:43 am

1 stop17h 02m

$520

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Sun 3/22

2:15 pm-4:07 pm

1 stop25h 52m

Panama City Tocumen Intl

Sat 3/28

3:41 pm-8:37 am

1 stop16h 56m

$526

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Sun 2/1

10:13 am-12:40 am

3 stops37h 27m

$213

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 1/12

7:37 pm-2:00 pm

2 stops17h 23m

$229

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Thu 1/8

7:14 pm-12:40 am

3 stops28h 26m

$230

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Fri 1/9

7:37 pm-10:30 am

2 stops13h 53m

$232

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Fri 1/9

5:10 am-1:27 pm

1 stop7h 17m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 16 results
1
2

Best time to book a flight from San Antonio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Panama

What is the cheapest month to book a flight from San Antonio to Panama?

Currently, July is the cheapest month in which you can book a flight from San Antonio to Panama (average of $343). Flying from San Antonio to Panama in January is currently the most expensive (average of $470). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to PA?

Find hourly flight availability from San Antonio to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

When flying from San Antonio to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 71% versus a flight in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 13, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,017 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to Panama?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to Panama from San Antonio.

  • How long is the flight from San Antonio to Panama?

    Departing from San Antonio to Panama will take you 7h 25m. There are 1876 mi between San Antonio and Panama. This flight may include one or multiple stops.

  • Can I find deals for flights from San Antonio to Panama that include hotel bookings?

    Yes. In addition to deals on San Antonio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Panama.

  • Can I find deals for business class flights from San Antonio to Panama?

    Yes. Cheapflights offers flight deals from San Antonio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Panama?

    Currently, July is the cheapest month in which you can book a flight from San Antonio to Panama (average of $343). Flying from San Antonio to Panama in January is currently the most expensive (average of $470). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Antonio to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from San Antonio to Panama

Discover the top 3 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$277Average$639FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$739FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$479Average$598FlexibilityNo cancel feeOn-time69%

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