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$224+ Cheap flights from San Antonio (SAT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from San Antonio to Panama

Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated September 15, 2025.

Round-trip from

$499
(United Airlines)

One-way from

$224
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$598
From San Antonio to Panama
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One-way flight from San Antonio to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Antonio to Panama

Cheapest flights from San Antonio to Panama
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:40 amSAT - PTY
1 stop6h 05mUnited Airlines
Tue 12/24:41 pmPTY - SAT
1 stop17h 00mUnited Airlines
Deal found 9/14$499
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:30 pmSAT - PTY
1 stop23h 08mUnited Airlines
Tue 12/24:41 pmPTY - SAT
1 stop7h 18mUnited Airlines
Deal found 9/14$506
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:40 amSAT - PTY
1 stop6h 58mUnited Airlines
Thu 11/278:55 amPTY - SAT
1 stop7h 34mUnited Airlines
Deal found 9/15$511
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:40 amSAT - PTY
1 stop6h 58mUnited Airlines
Wed 12/34:41 pmPTY - SAT
1 stop7h 18mUnited Airlines
Deal found 9/14$519
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:30 amSAT - PTY
1 stop8h 33mAmerican Airlines
Thu 11/62:49 pmPTY - SAT
2 stops19h 52mAmerican Airlines
Deal found 9/15$524
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:30 pmSAT - PTY
1 stop23h 08mUnited Airlines
Sun 11/164:41 pmPTY - SAT
1 stop17h 07mUnited Airlines
Deal found 9/13$526
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:30 amSAT - PTY
1 stop13h 07mUnited Airlines
Mon 10/273:41 pmPTY - SAT
1 stop17h 07mUnited Airlines
Deal found 9/14$539
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:05 pmSAT - PTY
2 stops18h 43mAmerican Airlines
Mon 12/82:50 pmPTY - SAT
2 stops19h 51mAmerican Airlines
Deal found 9/13$544
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:30 amSAT - PTY
1 stop8h 15mUnited Airlines
Sun 11/94:41 pmPTY - SAT
1 stop21h 23mUnited Airlines
Deal found 9/14$546
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:30 amSAT - PTY
1 stop8h 15mUnited Airlines
Sat 11/154:41 pmPTY - SAT
1 stop7h 15mUnited Airlines
Deal found 9/15$559
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:39 pmSAT - PTY
2 stops19h 24mAmerican Airlines
Mon 10/273:15 pmPTY - SAT
2 stops18h 04mAmerican Airlines
Deal found 9/14$564
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:30 pmSAT - PTY
1 stop18h 15mUnited Airlines
Sun 11/164:41 pmPTY - SAT
1 stop7h 15mUnited Airlines
Deal found 9/13$566

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.

Fly from

San Antonio

Fly to

Panama

Route

Depart

Return

Price

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 11/26

5:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Wed 12/3

4:41 pm-8:41 am

1 stop17h 00m

$499

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 11/25

11:40 am-7:38 pm

1 stop6h 58m

Panama City Tocumen Intl

Wed 12/3

4:41 pm-8:41 am

1 stop17h 00m

$499

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 11/24

7:40 am-2:45 pm

1 stop6h 05m

Panama City Tocumen Intl

Tue 12/2

4:41 pm-8:41 am

1 stop17h 00m

$499

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 11/25

7:40 am-7:38 pm

1 stop10h 58m

Panama City Tocumen Intl

Tue 12/2

4:41 pm-8:41 am

1 stop17h 00m

$499

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 11/24

7:40 am-2:45 pm

1 stop6h 05m

Panama City Tocumen Intl

Mon 12/1

4:41 pm-8:41 am

1 stop17h 00m

$499

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 11/26

7:40 am-2:45 pm

1 stop6h 05m

Panama City Tocumen Intl

Mon 12/1

4:41 pm-8:41 am

1 stop17h 00m

$499

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 3/9

6:50 pm-12:10 pm

2 stops17h 20m

Panama City Tocumen Intl

Wed 3/18

3:50 pm-12:24 am

1 stop8h 34m

$504

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 3/9

4:20 pm-1:45 pm

1 stop21h 25m

Panama City Tocumen Intl

Wed 3/18

7:55 am-9:13 pm

1 stop13h 18m

$506

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Sun 11/23

7:30 pm-2:45 pm

1 stop18h 15m

Panama City Tocumen Intl

Mon 12/1

4:41 pm-8:41 am

1 stop17h 00m

$506

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 11/26

7:40 am-2:45 pm

1 stop6h 05m

Panama City Tocumen Intl

Thu 11/27

4:41 pm-7:37 pm

1 stop27h 56m

$506

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 17 results
1
2

Best time to book a flight from San Antonio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Panama

What is the cheapest month to book a flight from San Antonio to Panama?

Currently, October is the cheapest month in which you can book a flight from San Antonio to Panama (average of $478). Flying from San Antonio to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to PA?

Find hourly flight availability from San Antonio to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from San Antonio to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 15, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to Panama?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to Panama from San Antonio.

  • How long is the flight from San Antonio to Panama?

    Departing from San Antonio to Panama will take you 8h 15m. There are 1876 mi between San Antonio and Panama.

  • Can I find deals for flights from San Antonio to Panama that include hotel bookings?

    Yes. In addition to deals on San Antonio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Panama.

  • Can I find deals for business class flights from San Antonio to Panama?

    Yes. Cheapflights offers flight deals from San Antonio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Panama?

    Currently, October is the cheapest month in which you can book a flight from San Antonio to Panama (average of $478). Flying from San Antonio to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from San Antonio to Panama

Discover the top 3 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$277Average$549FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$723FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$594FlexibilityNo cancel feeOn-time69%

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