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$213+ Cheap flights from San Antonio (SAT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
Nov 19 — Nov 261
Wed 11/19
Wed 11/26
1 adult, Economy
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Cheap flight deals from San Antonio to Panama

Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated October 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$500
(Delta)

One-way from

$213
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$559
Provider with most accurate pricing for San Antonio-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for San Antonio-Panama City Tocumen Intl flights.
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From San Antonio to Panama
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One-way flight from San Antonio to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from San Antonio to Panama

Cheapest flights from San Antonio to Panama
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:47 amSAT - PTY
1 stop5h 58mUnited Airlines
Tue 12/98:55 amPTY - SAT
1 stop12h 02mUnited Airlines
Deal found 10/18$520
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:05 pmSAT - PTY
2 stops20h 37mAmerican Airlines
Wed 12/104:43 pmPTY - SAT
2 stops19h 12mAmerican Airlines
Deal found 10/18$524
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1711:40 amSAT - PTY
1 stop6h 58mUnited Airlines
Tue 11/254:41 pmPTY - SAT
1 stop17h 07mUnited Airlines
Deal found 10/17$540
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:30 pmSAT - PTY
1 stop18h 15mUnited Airlines
Wed 11/264:41 pmPTY - SAT
1 stop17h 07mUnited Airlines
Deal found 10/17$546
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:30 pmSAT - PTY
1 stop18h 15mUnited Airlines
Thu 11/274:41 pmPTY - SAT
1 stop19h 02mUnited Airlines
Deal found 10/17$553
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:15 amSAT - PTY
1 stop7h 57mDelta
Sat 11/228:05 amPTY - SAT
1 stop13h 57mDelta
Deal found 10/20$560
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1711:25 amSAT - PTY
2 stops25h 24mAmerican Airlines
Sat 11/222:43 pmPTY - SAT
2 stops21h 10mAmerican Airlines
Deal found 10/20$564
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:24 pmSAT - PTY
1 stop21h 21mUnited Airlines
Fri 11/288:55 amPTY - SAT
1 stop15h 01mUnited Airlines
Deal found 10/17$566
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:24 pmSAT - PTY
1 stop21h 21mUnited Airlines
Tue 12/24:41 pmPTY - SAT
1 stop17h 00mUnited Airlines
Deal found 10/17$567
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:00 pmSAT - PTY
1 stop19h 45mUnited Airlines
Thu 11/274:41 pmPTY - SAT
1 stop21h 23mUnited Airlines
Deal found 10/17$573
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2311:40 amSAT - PTY
1 stop6h 58mUnited Airlines
Fri 11/284:41 pmPTY - SAT
1 stop17h 07mUnited Airlines
Deal found 10/18$580
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:00 pmSAT - PTY
1 stop19h 45mUnited Airlines
Fri 11/284:41 pmPTY - SAT
1 stop17h 07mUnited Airlines
Deal found 10/18$587

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.

Fly from

San Antonio

Fly to

Panama

Route

Depart

Return

Price

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Wed 12/3

7:47 am-2:45 pm

1 stop5h 58m

Panama City Tocumen Intl

Wed 12/10

11:35 am-9:32 pm

1 stop10h 57m

$520

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Sun 1/4

7:30 pm-2:45 pm

1 stop18h 15m

Panama City Tocumen Intl

Sun 1/11

4:41 pm-8:41 am

1 stop17h 00m

$526

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 11/18

5:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Tue 11/25

4:41 pm-10:56 pm

1 stop7h 15m

$540

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 11/17

11:40 am-7:38 pm

1 stop6h 58m

Panama City Tocumen Intl

Tue 11/25

4:41 pm-8:48 am

1 stop17h 07m

$540

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 11/17

9:45 am-7:38 pm

1 stop8h 53m

Panama City Tocumen Intl

Mon 12/1

4:41 pm-8:41 am

1 stop17h 00m

$540

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 11/24

11:40 am-7:38 pm

1 stop6h 58m

Panama City Tocumen Intl

Mon 12/1

4:41 pm-10:56 pm

1 stop7h 15m

$540

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 11/18

7:40 am-2:45 pm

1 stop6h 05m

Panama City Tocumen Intl

Wed 11/26

4:41 pm-8:48 am

1 stop17h 07m

$540

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Thu 11/20

5:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Wed 11/26

4:41 pm-10:56 pm

1 stop7h 15m

$540

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 11/18

5:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Mon 12/1

4:41 pm-10:56 pm

1 stop7h 15m

$540

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Sat 12/13

9:55 am-7:38 pm

1 stop8h 43m

Panama City Tocumen Intl

Sat 1/17

4:41 pm-10:57 pm

1 stop7h 16m

$540

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/18

Showing 1-10 of 23 results
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Best time to book a flight from San Antonio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Panama

What is the cheapest month to book a flight from San Antonio to Panama?

Currently, November is the cheapest month in which you can book a flight from San Antonio to Panama (average of $249). Flying from San Antonio to Panama in December is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to PA?

Find hourly flight availability from San Antonio to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2025.

When flying from San Antonio to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 71% versus a flight in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 20, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,976 reviews
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,994 reviews
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,026 reviews
Delta
7.9
Good
7,976 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to Panama?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to Panama from San Antonio.

  • How long is the flight from San Antonio to Panama?

    Departing from San Antonio to Panama will take you 5h 58m. There are 1876 mi between San Antonio and Panama.

  • Can I find deals for flights from San Antonio to Panama that include hotel bookings?

    Yes. In addition to deals on San Antonio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Panama.

  • Can I find deals for business class flights from San Antonio to Panama?

    Yes. Cheapflights offers flight deals from San Antonio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Panama?

    Currently, November is the cheapest month in which you can book a flight from San Antonio to Panama (average of $249). Flying from San Antonio to Panama in December is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Antonio to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from San Antonio to Panama

Discover the top 3 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$277Average$639FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$739FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$479Average$598FlexibilityNo cancel feeOn-time69%

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