$304+ Cheap flights from San Antonio (SAT) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
Nov 4 — Nov 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Antonio to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Panama
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Antonio to PanamaExplore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:53 pm -
1 stop8h 09m
Fri 12/119:26 pm -
1 stop16h 40m
Deal found 10/3![Multiple Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:30 am -
1 stop8h 15m
Sun 11/228:55 am -
1 stop13h 31m
Deal found 10/1![United Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:43 pm -
2 stops20h 30m
Sat 11/73:13 pm -
2 stops23h 02m
Deal found 10/1![American Airlines logo]()
$662
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:35 am -
1 stop28h 10m
Fri 12/118:55 am -
1 stop9h 42m
Deal found 10/4![United Airlines logo]()
$664
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:47 pm -
2 stops19h 26m
Sun 11/83:13 pm -
1 stop8h 06m
Deal found 10/3![American Airlines logo]()
$667
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:53 pm -
1 stop10h 14m
Mon 12/77:32 pm -
1 stop13h 29m
Deal found 10/3![Multiple Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:45 pm -
2 stops11h 26m
Mon 12/147:17 pm -
1 stop13h 44m
Deal found 10/3![Multiple Airlines logo]()
$673
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:53 pm -
1 stop8h 09m
Mon 12/79:26 pm -
1 stop11h 35m
Deal found 10/3![Multiple Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:40 pm -
2 stops18h 33m
Tue 11/243:34 pm -
2 stops20h 10m
Deal found 10/4![American Airlines logo]()
$680
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:17 pm -
2 stops17h 56m
Sun 2/212:39 pm -
1 stop27h 00m
Deal found 10/3![American Airlines logo]()
$682
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
1 stop13h 08m
Thu 11/268:55 am -
1 stop10h 08m
Deal found 10/5![United Airlines logo]()
$696
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:45 pm -
2 stops11h 26m
Mon 11/304:29 pm -
1 stop16h 32m
Deal found 10/3![Multiple Airlines logo]()
$697
Best flights from San Antonio to PanamaDiscover carefully curated flight deals from San Antonio to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
Discover carefully curated flight deals from San Antonio to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:30 am -
1 stop13h 08m
Tue 11/104:41 pm -
1 stop16h 48m
Deal found 10/4![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:30 am -
1 stop8h 15m
Sun 11/228:55 am -
1 stop13h 31m
Deal found 10/1![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:30 am -
1 stop13h 08m
Mon 12/148:55 am -
1 stop9h 42m
Deal found 10/3![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:35 am -
1 stop9h 03m
Mon 11/238:55 am -
1 stop14h 56m
Deal found 10/1![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:35 am -
1 stop11h 03m
Sun 11/84:41 pm -
1 stop16h 48m
Deal found 10/3![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/279:35 am -
1 stop9h 03m
Mon 2/14:41 pm -
1 stop7h 18m
Deal found 10/5![United Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:15 am -
1 stop13h 23m
Mon 12/74:41 pm -
1 stop7h 23m
Deal found 10/3![United Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
1 stop13h 08m
Thu 11/268:55 am -
1 stop10h 08m
Deal found 10/5![United Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:30 am -
1 stop8h 15m
Mon 11/304:41 pm -
1 stop7h 10m
Deal found 10/3![United Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:15 am -
1 stop8h 30m
Thu 12/244:41 pm -
1 stop16h 49m
Deal found 10/3![United Airlines logo]()
$707
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:08 pm -
1 stop18h 37m
Thu 12/244:41 pm -
1 stop16h 49m
Deal found 10/3![United Airlines logo]()
$715
Last-minute flights from San Antonio to PanamaDiscover last-minute flight deals from San Antonio to Panama. Data last updated October 5, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Panama. Data last updated October 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:35 am -
1 stop6h 10m
Mon 11/98:55 am -
1 stop14h 56m
Deal found 10/4![United Airlines logo]()
$708
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:00 pm -
2 stops22h 02m
Mon 11/93:13 pm -
2 stops24h 36m
Deal found 10/4![American Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:43 pm -
2 stops20h 30m
Sat 11/73:13 pm -
2 stops23h 02m
Deal found 10/1![American Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:47 pm -
2 stops19h 26m
Sun 11/83:13 pm -
1 stop8h 06m
Deal found 10/3![American Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:20 pm -
1 stop28h 18m
Mon 11/98:55 am -
1 stop10h 10m
Deal found 10/5![United Airlines logo]()
$716
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:30 am -
1 stop8h 15m
Sun 11/228:55 am -
1 stop13h 31m
Deal found 10/1![United Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:00 am -
1 stop8h 13m
Sun 11/223:34 pm -
2 stops19h 14m
Deal found 10/1![American Airlines logo]()
$736
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:35 am -
1 stop28h 10m
Fri 12/118:55 am -
1 stop9h 42m
Deal found 10/4![United Airlines logo]()
$664
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:40 pm -
2 stops18h 33m
Tue 11/243:34 pm -
2 stops20h 10m
Deal found 10/4![American Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
1 stop13h 08m
Thu 11/268:55 am -
1 stop10h 08m
Deal found 10/5![United Airlines logo]()
$696
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:45 pm -
2 stops11h 26m
Mon 12/147:17 pm -
1 stop13h 44m
Deal found 10/3![Multiple Airlines logo]()
$673
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:45 pm -
2 stops11h 26m
Mon 11/304:29 pm -
1 stop16h 32m
Deal found 10/3![Multiple Airlines logo]()
$697
One-way flights from San Antonio to PanamaSearch for one-way flight options from San Antonio to Panama. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
Search for one-way flight options from San Antonio to Panama. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:15 am -
1 stop10h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![United Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:53 pm -
1 stop15h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:20 pm -
1 stop28h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![United Airlines logo]()
$317
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:35 am -
1 stop11h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:19 pm -
1 stop26h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:53 pm -
1 stop15h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:15 am -
1 stop10h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:35 am -
1 stop11h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:37 pm -
2 stops19h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:47 pm -
2 stops19h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![American Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:00 am -
2 stops49h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:24 am -
2 stops28h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![American Airlines logo]()
$393
Find flight deals from San Antonio to Panama
Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated October 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $652 (Kiwi.com) |
One-way from | $304 (United Airlines) |
Popular in | December |
Cheapest in | February |
Average price | $669 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Mon 11/23
5:30 am-2:45 pm
1 stop8h 15m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$304
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Tue 12/1
5:15 am-5:12 pm
1 stop10h 57m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$304
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Wed 11/25
7:35 am-7:38 pm
1 stop11h 03m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$304
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Sun 11/22
2:20 pm-7:38 pm
1 stop28h 18m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$317
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Sun 1/3
7:08 pm-2:45 pm
1 stop18h 37m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$317
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Tue 11/10
7:35 am-7:38 pm
1 stop11h 03m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$338
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Sun 11/15
4:19 pm-7:38 pm
1 stop26h 19m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$351
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Fri 11/27
8:53 pm-1:46 pm
1 stop15h 53m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$355
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Sun 1/3
8:05 pm-1:33 pm
2 stops16h 28m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$357
San AntonioPanama City
SAT San Antonio - PTY Panama City Tocumen Intl
SATPTY
San Antonio
Fri 12/25
5:15 am-5:12 pm
1 stop10h 57m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$357
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from San Antonio to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
SAT-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Panama
SAT-PA0
SAT-PTY
What is the cheapest month to book a flight from San Antonio to Panama?
Currently, February is the cheapest month in which you can book a flight from San Antonio to Panama (average of $580). Flying from San Antonio to Panama in December is currently the most expensive (average of $803). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from San Antonio to Panama?
Booking 38 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 5, 2026.
See what other customers who have flown with Copa Airlines and United Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Overall
7.6
Entertainment
6.9
Boarding
7.8
Food
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Overall
7.6
Entertainment
6.9
Boarding
7.8
Food
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Overall
7.6
Entertainment
6.9
Boarding
7.8
Food
6.9
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Alternative routes for San Antonio to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Antonio to Panama by cabin class
Find flights from San Antonio to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Antonio and Panama flights
Browse other San Antonio and Panama flight options. Last updated on October 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from San Antonio to Panama
Discover the top 2 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$539 | Average$708 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$592 | Average$671 | FlexibilityNo cancel fee | On-time70% |