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$269+ Cheap flights from Portland (PDX) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — PTY
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
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Cheap flight deals from Portland to Panama

Keep the following information in mind while searching for Portland to Panama flight deals. Data was last updated January 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$578
(Travelocity)

One-way from

$269
(Orbitz)

Popular in

December

Cheapest in

May

Average price

$704
Provider with most accurate pricing for Portland-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Portland-Panama City Tocumen Intl flights.
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From Portland to Panama
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One-way flight from Portland to Panama
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Highest demand for flights based on searches. 1% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Portland to Panama

Cheapest flights from Portland to Panama
Explore the most affordable flight options available from Portland to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This Expedia deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:00 amPDX - PTY
2 stops27h 35mMultiple Airlines
Sat 4/258:10 pmPTY - PDX
2 stops25h 52mMultiple Airlines
Deal found 1/6$585
This Travelocity deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:00 amPDX - PTY
3 stops25h 30mMultiple Airlines
Fri 4/108:10 pmPTY - PDX
2 stops25h 36mMultiple Airlines
Deal found 1/6$589
This Expedia deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/310:46 amPDX - PTY
2 stops20h 44mMultiple Airlines
Tue 2/107:50 pmPTY - PDX
2 stops27h 58mMultiple Airlines
Deal found 1/4$594
This Expedia deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:45 amPDX - PTY
2 stops44h 45mMultiple Airlines
Wed 2/257:50 pmPTY - PDX
2 stops27h 11mMultiple Airlines
Deal found 1/4$605
This Expedia deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:00 amPDX - PTY
3 stops48h 30mMultiple Airlines
Thu 2/267:50 pmPTY - PDX
2 stops27h 11mMultiple Airlines
Deal found 1/5$610
This Travelocity deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/127:00 amPDX - PTY
2 stops56h 55mMultiple Airlines
Mon 1/197:50 pmPTY - PDX
2 stops26h 22mMultiple Airlines
Deal found 1/3$611
This Expedia deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/237:00 amPDX - PTY
2 stops48h 30mMultiple Airlines
Mon 2/27:50 pmPTY - PDX
3 stops27h 37mMultiple Airlines
Deal found 1/3$614
This Orbitz deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:00 amPDX - PTY
3 stops25h 30mMultiple Airlines
Sat 3/143:50 pmPTY - PDX
2 stops30h 11mMultiple Airlines
Deal found 1/6$622
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 amPDX - PTY
1 stop22h 06mMultiple Airlines
Fri 3/63:50 pmPTY - PDX
2 stops22h 06mMultiple Airlines
Deal found 1/6$628
This Orbitz deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:35 amPDX - PTY
2 stops21h 50mMultiple Airlines
Tue 4/218:10 pmPTY - PDX
2 stops25h 52mMultiple Airlines
Deal found 1/4$636
This Orbitz deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/292:43 pmPDX - PTY
2 stops25h 12mMultiple Airlines
Thu 2/57:50 pmPTY - PDX
2 stops26h 22mMultiple Airlines
Deal found 1/3$637

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Portland to Panama that are best for you.

Fly from

Portland

Fly to

Panama

Route

Depart

Return

Price

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Tue 2/3

10:46 am-10:30 am

2 stops20h 44m

Panama City Tocumen Intl

Tue 2/10

7:50 pm-8:48 pm

2 stops27h 58m

$594

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Thu 2/19

7:00 am-10:30 am

3 stops48h 30m

Panama City Tocumen Intl

Thu 2/26

7:50 pm-8:01 pm

2 stops27h 11m

$610

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Fri 1/23

7:00 am-10:30 am

2 stops48h 30m

Panama City Tocumen Intl

Mon 2/2

7:50 pm-7:12 pm

2 stops26h 22m

$611

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Thu 2/5

7:00 am-10:30 am

2 stops48h 30m

Panama City Tocumen Intl

Mon 2/9

7:50 pm-7:12 pm

2 stops26h 22m

$611

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Tue 4/7

10:35 am-10:25 am

2 stops21h 50m

Panama City Tocumen Intl

Tue 4/21

8:10 pm-8:02 pm

2 stops25h 52m

$636

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Mon 3/9

7:00 am-8:37 pm

1 stop11h 37m

Panama City Tocumen Intl

Sat 3/14

3:50 pm-11:52 am

2 stops22h 02m

$638

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Thu 1/29

2:43 pm-6:55 pm

2 stops25h 12m

Panama City Tocumen Intl

Thu 2/5

7:50 pm-8:27 pm

3 stops27h 37m

$640

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Wed 2/25

7:10 am-7:38 pm

1 stop9h 28m

Panama City Tocumen Intl

Mon 3/2

4:41 pm-12:38 pm

2 stops22h 57m

$661

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Tue 4/7

5:00 am-6:37 pm

2 stops11h 37m

Panama City Tocumen Intl

Tue 4/21

7:55 am-10:58 pm

1 stop17h 03m

$661

PortlandPanama City

PDX - PTY

PDXPTY

Portland

Wed 2/25

7:10 am-7:38 pm

1 stop9h 28m

Panama City Tocumen Intl

Wed 3/4

8:55 am-10:59 pm

1 stop17h 04m

$661

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/5

Showing 1-10 of 18 results
1
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Best time to book a flight from Portland to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Panama

What is the cheapest month to book a flight from Portland to Panama?

Currently, March is the cheapest month in which you can book a flight from Portland to Panama (average of $385). Flying from Portland to Panama in September is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 6, 2026.
See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Portland to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,022 reviews

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,022 reviews
Delta
7.9
Good
8,022 reviews

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,564 reviews
Delta
7.9
Good
8,022 reviews

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,138 reviews
Delta
7.9
Good
8,022 reviews

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,088 reviews
Delta
7.9
Good
8,022 reviews

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Portland to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Panama?

    Most people fly from Portland (PDX) if they book a flight from Portland to Panama. Portland is conveniently located just 6.0 mi from Portland’s city center.

  • Can I find deals for flights from Portland to Panama that include hotel bookings?

    Yes. In addition to deals on Portland to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Panama.

  • Can I find deals for business class flights from Portland to Panama?

    Yes. Cheapflights offers flight deals from Portland to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Panama?

    Currently, March is the cheapest month in which you can book a flight from Portland to Panama (average of $385). Flying from Portland to Panama in September is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Portland to Panama

Discover the top 4 airlines that operate flights from Portland to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$821FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$500Average$1,131FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$649Average$730FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$691Average$945FlexibilityNo cancel feeOn-time70%

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