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$185+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
mars 13 — mars 201
ven. 3/13
ven. 3/20
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on février 11, 2026.

This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 4/156:10 am
CMH
-
PTY
1 stop13h 27m
United Airlines
lun. 4/2010:55 pm
PTY
-
CMH
1 stop10h 56m
United Airlines
Deal found 2/8$435
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/249:49 am
CMH
-
PTY
1 stop10h 42m
United Airlines
lun. 4/2710:55 pm
PTY
-
CMH
1 stop10h 56m
United Airlines
Deal found 2/9$443
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/2811:39 am
CMH
-
PTY
1 stop7h 58m
United Airlines
ven. 5/13:30 pm
PTY
-
CMH
1 stop18h 22m
United Airlines
Deal found 2/8$452
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/249:49 am
CMH
-
PTY
1 stop10h 42m
United Airlines
dim. 4/267:55 am
PTY
-
CMH
1 stop13h 08m
United Airlines
Deal found 2/9$460
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 5/16:15 pm
CMH
-
PTY
1 stop19h 31m
American Airlines
ven. 5/81:49 pm
PTY
-
CMH
2 stops21h 41m
American Airlines
Deal found 2/9$467
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 5/16:15 am
CMH
-
PTY
1 stop8h 59m
United Airlines
ven. 5/83:30 pm
PTY
-
CMH
1 stop18h 22m
United Airlines
Deal found 2/8$469
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 3/1111:38 am
CMH
-
DAV
2 stops22h 26m
United Airlines
mer. 3/189:48 am
DAV
-
CMH
2 stops24h 13m
United Airlines
Deal found 2/9$860
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 8/2211:35 am
CMH
-
DAV
2 stops22h 33m
United Airlines
mer. 8/269:50 am
DAV
-
CMH
2 stops24h 09m
United Airlines
Deal found 2/8$1,006
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/17:00 am
CMH
-
DAV
2 stops27h 08m
Copa Airlines
lun. 6/158:31 am
DAV
-
CMH
2 stops24h 33m
Copa Airlines
Deal found 2/9$1,012
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 3/266:30 am
CMH
-
DAV
2 stops27h 34m
United Airlines
jeu. 4/210:05 am
DAV
-
CMH
2 stops23h 46m
United Airlines
Deal found 2/9$1,099
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/36:45 am
CMH
-
DAV
2 stops27h 25m
United Airlines
sam. 10/319:50 am
DAV
-
CMH
2 stops25h 09m
United Airlines
Deal found 2/8$1,221

Find flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated février 11, 2026.

Round-trip from

$435
(United Airlines)

One-way from

$185
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$621
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($225 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($81 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated février 11, 2026.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 3/25

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

mer. 4/1

9:45 am-9:59 pm

1 stop11h 14m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 4/15

6:10 am-6:37 pm

1 stop13h 27m

Panama City Tocumen Intl

lun. 4/20

10:55 pm-10:51 am

1 stop10h 56m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

ven. 4/24

9:49 am-7:31 pm

1 stop10h 42m

Panama City Tocumen Intl

lun. 4/27

10:55 pm-10:51 am

1 stop10h 56m

$443

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 3/10

6:30 am-1:45 pm

1 stop8h 15m

Panama City Tocumen Intl

mar. 3/17

3:41 pm-4:46 pm

2 stops24h 05m

$449

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

mer. 3/11

11:38 am-9:04 am

2 stops22h 26m

David Enrique Malek

mer. 3/18

9:48 am-11:01 am

2 stops24h 13m

$860

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

lun. 6/1

7:00 am-9:08 am

2 stops27h 08m

David Enrique Malek

lun. 6/15

8:31 am-10:04 am

2 stops24h 33m

$1,012

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

jeu. 4/16

5:40 am-6:37 pm

2 stops13h 57m

$185

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 4/15

6:06 am-1:02 pm

1 stop7h 56m

$185

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 5/27

3:47 pm-12:14 pm

2 stops21h 27m

$185

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 4/15

9:49 am-7:31 pm

1 stop10h 42m

$185

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/8

Showing 1-10 of 13 results
1
2

Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $311). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated février 11, 2026.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,179 reviews

Food

7.2

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,179 reviews
Delta
7.9
Good
8,179 reviews

Food

7.2

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,276 reviews
Delta
7.9
Good
8,179 reviews

Food

7.2

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,267 reviews
Delta
7.9
Good
8,179 reviews

Food

7.2

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like United Airlines and Copa Airlines fly from Columbus Airport to Panama in about 13h 08m. The time it takes to get you to your destination can typically vary by up to 14h. Columbus Airport and Panama are separated by a distance of 2146 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $311). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated février 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$359Average$508FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$627FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$570FlexibilityNo cancel feeOn-time69%

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