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$170+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:00 amCMH - PTY
1 stop7h 21mDelta
Thu 12/113:46 pmPTY - CMH
1 stop8h 28mDelta
Deal found 12/2$612
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:37 amCMH - PTY
1 stop8h 01mUnited Airlines
Thu 12/1111:55 pmPTY - CMH
2 stops15h 31mUnited Airlines
Deal found 12/2$616
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:00 amCMH - PTY
1 stop12h 59mDelta
Mon 12/83:46 pmPTY - CMH
1 stop8h 28mDelta
Deal found 12/2$632
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amCMH - PTY
2 stops9h 42mAmerican Airlines
Mon 12/84:43 pmPTY - CMH
2 stops19h 33mAmerican Airlines
Deal found 12/2$636
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:11 pmCMH - PTY
1 stop6h 49mDelta
Mon 12/298:00 amPTY - CMH
1 stop9h 26mDelta
Deal found 12/2$817
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:10 amCMH - PTY
1 stop10h 57mUnited Airlines
Mon 12/2911:35 amPTY - CMH
1 stop11h 54mUnited Airlines
Deal found 12/3$861
This Kiwi.com deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:35 pmCMH - PTY
1 stop25h 58mMultiple Airlines
Thu 1/17:31 amPTY - CMH
2 stops16h 26mMultiple Airlines
Deal found 12/1$905
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:21 pmCMH - PTY
2 stops22h 32mAmerican Airlines
Mon 12/294:55 pmPTY - CMH
2 stops19h 14mAmerican Airlines
Deal found 12/2$961
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:33 pmCMH - PTY
3 stops20h 22mMultiple Airlines
Thu 12/1111:25 amPTY - CMH
2 stops10h 49mMultiple Airlines
Deal found 12/2$998

Find flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated December 4, 2025.

Round-trip from

$414
(Delta)

One-way from

$170
(Delta)

Popular in

December

Cheapest in

October

Average price

$1,197
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($178 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($54 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

11:22 am-8:02 pm

1 stop8h 40m

Panama City Tocumen Intl

Wed 1/28

10:00 am-8:58 pm

1 stop10h 58m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 1/29

3:20 pm-12:04 am

1 stop8h 44m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 1/27

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Wed 1/28

4:41 pm-11:04 am

1 stop18h 23m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 2/10

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Tue 2/17

8:55 am-10:12 pm

1 stop13h 17m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 5/6

6:45 am-4:12 pm

1 stop10h 27m

Panama City Tocumen Intl

Tue 5/12

7:55 am-9:50 pm

1 stop12h 55m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 2/10

5:45 am-7:38 pm

2 stops13h 53m

Panama City Tocumen Intl

Mon 2/16

4:41 pm-10:12 pm

1 stop29h 31m

$427

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 3/4

5:30 am-7:38 pm

2 stops14h 08m

Panama City Tocumen Intl

Sun 3/8

10:55 pm-4:46 pm

2 stops16h 51m

$435

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Thu 1/22

11:22 am-5:30 pm

2 stops30h 08m

David Enrique Malek

Mon 1/26

9:50 am-10:29 pm

2 stops36h 39m

$853

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Sat 1/17

6:30 am-9:10 am

2 stops26h 40m

David Enrique Malek

Sat 1/24

9:50 am-9:50 am

2 stops24h 00m

$1,516

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 1/8

6:00 am-1:55 pm

1 stop7h 55m

$170

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 18 results
1
2

Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 12% on flights from Columbus Airport to Panama by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,066 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like United Airlines and Delta fly from Columbus Airport to Panama in about 7h 55m. The time it takes to get you to your destination can typically vary by up to 45m. Columbus Airport and Panama are separated by a distance of 2146 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$553FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$582FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$582FlexibilityNo cancel feeOn-time69%

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