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$174+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
nov. 15 — nov. 221
sáb. 11/15
sáb. 11/22
1 adult, Economy
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Find flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/138:17 pmCMH - PTY
2 stops17h 32mAmerican Airlines
mié. 11/192:49 pmPTY - CMH
1 stop8h 48mAmerican Airlines
Deal found 10/16$408
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/137:57 pmCMH - PTY
1 stop24h 02mDelta
mié. 11/193:37 pmPTY - CMH
1 stop24h 07mDelta
Deal found 10/16$424
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/36:30 amCMH - PTY
1 stop10h 37mUnited Airlines
dom. 12/711:35 amPTY - CMH
1 stop10h 54mUnited Airlines
Deal found 10/14$431
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/3010:00 pmCMH - PTY
2 stops16h 45mUnited Airlines
dom. 12/711:55 pmPTY - CMH
2 stops15h 31mUnited Airlines
Deal found 10/15$435
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/35:16 pmCMH - PTY
2 stops20h 31mAmerican Airlines
dom. 12/72:50 pmPTY - CMH
2 stops18h 39mAmerican Airlines
Deal found 10/14$440
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/224:45 pmCMH - PTY
1 stop26h 53mUnited Airlines
mié. 11/264:41 pmPTY - CMH
1 stop18h 14mUnited Airlines
Deal found 10/15$492
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/224:59 pmCMH - PTY
2 stops20h 44mAmerican Airlines
mié. 11/262:43 pmPTY - CMH
2 stops19h 39mAmerican Airlines
Deal found 10/15$535
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/155:42 pmCMH - PTY
2 stops21h 32mUnited Airlines
vie. 10/173:30 pmPTY - CMH
2 stops20h 47mUnited Airlines
Deal found 10/15$636
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/163:54 pmCMH - PTY
2 stops23h 09mAmerican Airlines
dom. 10/193:15 pmPTY - CMH
2 stops23h 10mAmerican Airlines
Deal found 10/16$641

Cheap flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated octubre 16, 2025.

Round-trip from

$408
(American Airlines)

One-way from

$174
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$472
From Columbus to Panama
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One-way flight from Columbus to Panama
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Highest demand for flights based on searches. 5% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 16, 2025.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

jue. 11/13

8:17 pm-1:49 pm

2 stops17h 32m

Panama City Tocumen Intl

mié. 11/19

2:49 pm-11:37 pm

1 stop8h 48m

$408

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

jue. 4/2

6:45 am-4:12 pm

1 stop10h 27m

Panama City Tocumen Intl

mar. 4/7

7:55 am-9:50 pm

1 stop12h 55m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mié. 2/18

9:00 am-8:02 pm

1 stop11h 02m

Panama City Tocumen Intl

mié. 2/25

10:00 am-7:11 pm

1 stop9h 11m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

dom. 4/5

4:40 pm-2:14 pm

1 stop22h 34m

Panama City Tocumen Intl

mar. 4/7

3:20 pm-10:59 am

1 stop18h 39m

$423

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

jue. 11/13

7:57 pm-7:59 pm

1 stop24h 02m

Panama City Tocumen Intl

mié. 11/19

3:37 pm-3:44 pm

1 stop24h 07m

$424

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mié. 12/3

6:30 am-5:07 pm

1 stop10h 37m

Panama City Tocumen Intl

dom. 12/7

11:35 am-10:29 pm

1 stop10h 54m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mié. 3/4

5:30 am-5:07 pm

2 stops11h 37m

Panama City Tocumen Intl

dom. 3/8

10:55 pm-4:51 pm

2 stops16h 56m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 3/3

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

dom. 3/8

10:55 pm-3:32 pm

2 stops15h 37m

$435

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

mar. 3/3

6:30 am-9:04 am

2 stops26h 34m

David Enrique Malek

vie. 3/6

9:48 am-11:04 am

2 stops25h 16m

$1,000

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

jue. 4/2

6:45 am-2:14 pm

1 stop8h 29m

$174

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 14 results
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Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 16, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 12% on flights from Columbus Airport to Panama by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated octubre 16, 2025.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,984 reviews
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,982 reviews
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,043 reviews
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like American Airlines and United Airlines fly from Columbus Airport to Panama in about 10h 27m. The time it takes to get you to your destination can typically vary by up to 7h 05m. Columbus Airport and Panama are separated by a distance of 2146 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$553FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$430Average$545FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$450Average$575FlexibilityNo cancel feeOn-time71%

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