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$190+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:49 am
CMH
-
PTY
1 stop10h 42m
United Airlines
Mon 4/203:30 pm
PTY
-
CMH
1 stop18h 27m
United Airlines
Deal found 2/17$445
This BusinessClass deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:05 am
CMH
-
PTY
1 stop13h 26m
Copa Airlines
Tue 4/2810:00 am
PTY
-
CMH
1 stop11h 03m
Copa Airlines
Deal found 2/15$447
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:45 am
CMH
-
PTY
1 stop8h 29m
United Airlines
Mon 9/73:20 pm
PTY
-
CMH
1 stop29h 30m
United Airlines
Deal found 2/15$454
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 am
CMH
-
PTY
2 stops12h 37m
United Airlines
Thu 5/143:30 pm
PTY
-
CMH
1 stop29h 41m
United Airlines
Deal found 2/16$459
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:10 am
CMH
-
PTY
1 stop9h 04m
United Airlines
Fri 5/110:00 am
PTY
-
CMH
1 stop11h 11m
United Airlines
Deal found 2/15$462
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
CMH
-
PTY
1 stop8h 02m
Delta
Wed 5/132:20 pm
PTY
-
CMH
1 stop8h 55m
Delta
Deal found 2/18$465
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 am
CMH
-
PTY
2 stops12h 37m
United Airlines
Wed 5/1310:00 am
PTY
-
CMH
2 stops14h 13m
United Airlines
Deal found 2/18$469
This Gurufare deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:15 am
CMH
-
PTY
1 stop8h 59m
Copa Airlines
Mon 5/113:30 pm
PTY
-
CMH
1 stop18h 22m
Copa Airlines
Deal found 2/18$475
This BusinessClass deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:41 pm
CMH
-
PTY
1 stop19h 14m
LATAM Airlines
Thu 5/142:20 pm
PTY
-
CMH
1 stop24h 32m
LATAM Airlines
Deal found 2/16$477
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:45 am
CMH
-
DAV
2 stops27h 23m
United Airlines
Wed 8/269:50 am
DAV
-
CMH
2 stops24h 09m
United Airlines
Deal found 2/16$1,016
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:45 am
CMH
-
DAV
2 stops11h 49m
United Airlines
Sat 10/319:50 am
DAV
-
CMH
2 stops24h 05m
United Airlines
Deal found 2/16$1,222

Find flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated February 18, 2026.

Round-trip from

$445
(United Airlines)

One-way from

$190
(United Airlines)

Popular in

December

Cheapest in

May

Average price

$621
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($230 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($81 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 3/18

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Wed 3/25

3:41 pm-11:01 am

1 stop18h 20m

$445

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 3/31

11:39 am-6:37 pm

1 stop7h 58m

Panama City Tocumen Intl

Tue 4/7

3:30 pm-10:57 am

1 stop18h 27m

$445

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

9:49 am-7:31 pm

1 stop10h 42m

Panama City Tocumen Intl

Mon 4/20

10:55 pm-10:51 am

1 stop10h 56m

$445

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/16

6:10 am-2:14 pm

1 stop9h 04m

Panama City Tocumen Intl

Mon 4/20

10:55 pm-10:51 am

1 stop10h 56m

$445

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 3/17

5:30 am-4:07 pm

2 stops11h 37m

Panama City Tocumen Intl

Tue 3/24

3:41 pm-11:01 am

1 stop18h 20m

$449

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/22

9:49 am-7:31 pm

1 stop10h 42m

$190

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 3/1

11:17 am-2:00 pm

3 stops26h 43m

$204

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 5/1

6:00 am-1:02 pm

1 stop8h 02m

$207

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 5/1

2:57 pm-12:46 pm

2 stops22h 49m

$207

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 5/1

3:36 pm-2:15 pm

3 stops23h 39m

$231

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Showing 1-10 of 12 results
1
2

Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $321). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 18, 2026.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,208 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,208 reviews
Delta
7.9
Good
8,208 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,315 reviews
Delta
7.9
Good
8,208 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,307 reviews
Delta
7.9
Good
8,208 reviews

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like United Airlines fly from Columbus Airport to Panama in about 13h 08m. The time it takes to get you to your destination can typically vary by up to . Columbus Airport and Panama are separated by a distance of 2146 mi.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $321). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$263Average$507FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$627FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$413Average$549FlexibilityNo cancel feeOn-time69%

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