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$174+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:45 pmCMH - PTY
1 stop26h 53mUnited Airlines
Mon 12/228:55 amPTY - CMH
1 stop14h 34mUnited Airlines
Deal found 12/17$644
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:45 pmCMH - PTY
1 stop22h 00mUnited Airlines
Tue 12/2311:35 amPTY - CMH
2 stops12h 09mUnited Airlines
Deal found 12/17$648
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:10 amCMH - PTY
1 stop13h 28mUnited Airlines
Mon 12/2911:35 amPTY - CMH
1 stop11h 54mUnited Airlines
Deal found 12/16$666
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:37 pmCMH - PTY
2 stops22h 16mAmerican Airlines
Mon 12/294:55 pmPTY - CMH
2 stops17h 37mAmerican Airlines
Deal found 12/17$770
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/274:45 pmCMH - PTY
1 stop22h 00mUnited Airlines
Wed 6/243:20 pmPTY - CMH
1 stop18h 39mUnited Airlines
Deal found 12/16$832

Find flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated December 18, 2025.

Round-trip from

$414
(United Airlines)

One-way from

$174
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$1,258
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($177 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Thu 1/29

8:55 am-10:29 pm

1 stop13h 34m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

6:30 am-5:07 pm

1 stop10h 37m

Panama City Tocumen Intl

Wed 1/28

4:41 pm-11:04 am

1 stop18h 23m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 4/6

9:30 am-7:31 pm

1 stop11h 01m

Panama City Tocumen Intl

Mon 4/13

7:55 am-10:15 pm

1 stop13h 20m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

7:10 pm-1:27 pm

2 stops18h 17m

Panama City Tocumen Intl

Thu 1/29

4:50 pm-12:44 am

1 stop7h 54m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 3/4

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Sun 3/8

9:30 am-8:10 pm

1 stop9h 40m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 1/21

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Sun 1/25

4:41 pm-11:04 am

1 stop18h 23m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 1/22

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Sun 1/25

4:41 pm-11:04 am

1 stop18h 23m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 1/30

6:30 am-5:07 pm

1 stop10h 37m

Panama City Tocumen Intl

Mon 2/2

8:55 am-10:29 pm

1 stop13h 34m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 1/21

11:22 am-8:02 pm

1 stop8h 40m

Panama City Tocumen Intl

Sat 1/24

4:41 pm-11:04 am

1 stop18h 23m

$431

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Wed 4/29

11:40 am-9:08 am

2 stops22h 28m

David Enrique Malek

Sat 5/2

9:55 am-10:44 am

2 stops23h 49m

$1,000

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 18 results
1
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Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 12% on flights from Columbus Airport to Panama by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like United Airlines fly from Columbus Airport to Panama in about 13h 08m. The time it takes to get you to your destination can typically vary by up to . Columbus Airport and Panama are separated by a distance of 2146 mi.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$548FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$632FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$585FlexibilityNo cancel feeOn-time69%

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