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$174+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Find flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:26 pmCMH - PTY
1 stop7h 33mDelta
Sat 12/138:05 amPTY - CMH
1 stop7h 29mDelta
Deal found 11/4$550
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:58 pmCMH - PTY
2 stops20h 47mUnited Airlines
Sat 12/134:41 pmPTY - CMH
1 stop18h 15mUnited Airlines
Deal found 11/4$554
This Avianca Connect deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/159:42 amCMH - PTY
2 stops15h 18mMultiple Airlines
Fri 12/122:55 amPTY - CMH
2 stops19h 19mMultiple Airlines
Deal found 11/4$619
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:37 pmCMH - PTY
2 stops22h 16mAmerican Airlines
Mon 12/292:53 pmPTY - CMH
2 stops19h 31mAmerican Airlines
Deal found 11/4$720
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:05 amCMH - PTY
1 stop11h 55mDelta
Mon 12/298:00 amPTY - CMH
1 stop9h 26mDelta
Deal found 11/5$758
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:05 pmCMH - PTY
2 stops20h 48mAmerican Airlines
Sun 12/284:55 pmPTY - CMH
2 stops19h 14mAmerican Airlines
Deal found 11/4$759
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:10 amCMH - PTY
1 stop10h 57mUnited Airlines
Mon 12/2911:55 pmPTY - CMH
1 stop9h 08mUnited Airlines
Deal found 11/4$797
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:15 pmCMH - DAV
2 stops25h 09mUnited Airlines
Sat 12/279:50 amDAV - CMH
2 stops23h 13mUnited Airlines
Deal found 11/4$1,762

Cheap flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated November 5, 2025.

Round-trip from

$414
(United Airlines)

One-way from

$174
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$585
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($186 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Thu 1/29

10:00 am-7:31 pm

1 stop9h 31m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 2/18

12:05 pm-8:02 pm

1 stop7h 57m

Panama City Tocumen Intl

Wed 2/25

10:00 am-7:59 pm

1 stop9h 59m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:45 am-2:14 pm

1 stop8h 29m

Panama City Tocumen Intl

Mon 4/6

10:55 pm-9:54 am

1 stop9h 59m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Tue 4/7

10:55 pm-3:14 pm

2 stops15h 19m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

7:00 am-8:02 pm

2 stops13h 02m

Panama City Tocumen Intl

Wed 1/28

8:55 am-10:29 pm

1 stop13h 34m

$418

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Tue 3/3

9:00 am-5:31 pm

2 stops32h 31m

David Enrique Malek

Fri 3/6

9:48 am-7:59 pm

2 stops34h 11m

$937

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Sat 12/20

4:15 pm-5:24 pm

2 stops25h 09m

David Enrique Malek

Sat 12/27

9:50 am-9:03 am

2 stops23h 13m

$1,762

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:45 am-2:14 pm

1 stop8h 29m

$174

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

8:25 pm-2:20 pm

2 stops18h 55m

$174

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Fri 12/26

5:35 pm-7:33 pm

1 stop25h 58m

$381

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $496). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 12% on flights from Columbus Airport to Panama by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 5, 2025.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,004 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,004 reviews
Delta
7.9
Good
8,004 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,002 reviews
Delta
7.9
Good
8,004 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,042 reviews
Delta
7.9
Good
8,004 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like United Airlines fly from Columbus Airport to Panama in about 13h 08m. The time it takes to get you to your destination can typically vary by up to . Columbus Airport and Panama are separated by a distance of 2146 mi.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $496). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$550FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$430Average$554FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$450Average$591FlexibilityNo cancel feeOn-time71%

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