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$151+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated August 20, 2025.

Round-trip from

$413
(United Airlines)

One-way from

$151
(Avianca Connect)

Popular in

December

Cheapest in

October

Average price

$536
From Columbus to Panama
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One-way flight from Columbus to Panama
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Highest demand for flights based on searches. 19% potential increase in price ($147 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:15 amCMH - PTY
1 stop13h 22mUnited Airlines
Mon 10/2010:00 amPTY - CMH
1 stop11h 15mUnited Airlines
Deal found 8/19$413
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:15 amCMH - PTY
1 stop13h 22mUnited Airlines
Thu 10/303:41 pmPTY - CMH
2 stops16h 49mUnited Airlines
Deal found 8/18$418
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:15 amCMH - PTY
1 stop8h 59mUnited Airlines
Mon 9/223:30 pmPTY - CMH
1 stop29h 43mUnited Airlines
Deal found 8/18$422
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:16 pmCMH - PTY
2 stops19h 15mAmerican Airlines
Thu 10/93:15 pmPTY - CMH
1 stop26h 30mAmerican Airlines
Deal found 8/18$428
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:50 pmCMH - PTY
2 stops20h 13mAmerican Airlines
Mon 10/203:15 pmPTY - CMH
2 stops19h 50mAmerican Airlines
Deal found 8/18$435
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:00 amCMH - PTY
2 stops12h 37mUnited Airlines
Fri 10/103:30 pmPTY - CMH
2 stops22h 53mUnited Airlines
Deal found 8/19$452
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/88:33 pmCMH - PTY
2 stops18h 30mAmerican Airlines
Thu 10/303:15 pmPTY - CMH
2 stops19h 25mAmerican Airlines
Deal found 8/18$481
This Avianca Connect deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1512:31 pmCMH - PTY
2 stops13h 14mMultiple Airlines
Sun 9/213:20 amPTY - CMH
2 stops14h 38mMultiple Airlines
Deal found 8/18$486
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:55 pmCMH - PTY
1 stop21h 08mAmerican Airlines
Thu 10/303:15 pmPTY - CMH
2 stops20h 58mAmerican Airlines
Deal found 8/19$493
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/86:08 amCMH - PTY
1 stop8h 42mUnited Airlines
Mon 9/153:30 pmPTY - CMH
2 stops20h 45mUnited Airlines
Deal found 8/18$496
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:00 amCMH - PTY
2 stops12h 37mUnited Airlines
Sat 10/113:30 pmPTY - CMH
2 stops20h 47mUnited Airlines
Deal found 8/20$498
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:15 amCMH - DAV
2 stops27h 43mUnited Airlines
Mon 10/209:44 amDAV - CMH
2 stops35h 18mUnited Airlines
Deal found 8/19$838

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 10/8

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Thu 10/30

7:55 am-10:12 pm

1 stop13h 17m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 10/2

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Thu 10/9

9:45 am-10:02 pm

1 stop11h 17m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 10/8

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Mon 10/20

10:00 am-10:15 pm

1 stop11h 15m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 10/28

6:30 am-1:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Mon 11/10

8:55 am-10:12 pm

1 stop13h 17m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 10/9

5:41 pm-2:03 pm

2 stops21h 22m

Panama City Tocumen Intl

Thu 10/30

3:15 pm-3:25 pm

2 stops23h 10m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 10/2

5:37 am-2:31 pm

2 stops9h 54m

Panama City Tocumen Intl

Thu 10/9

3:15 pm-12:47 pm

2 stops20h 32m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 9/15

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Mon 9/22

3:30 pm-9:38 am

2 stops17h 08m

$418

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Wed 10/8

6:15 am-8:58 am

2 stops27h 43m

David Enrique Malek

Mon 10/20

9:44 am-8:35 pm

2 stops33h 51m

$838

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 9/17

5:15 am-12:45 am

2 stops20h 30m

$151

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 9/3

5:15 am-12:45 am

2 stops20h 30m

$163

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 17 results
1
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Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, October is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $478). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbus Airport to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 20, 2025.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,928 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like United Airlines fly from Columbus Airport to Panama in about 8h 59m. The time it takes to get you to your destination can typically vary by up to . Columbus Airport and Panama are separated by a distance of 2146 mi.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, October is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $478). Flying from Columbus Airport to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$562FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$447Average$564FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$468Average$571FlexibilityNo cancel feeOn-time71%

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