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$184+ Cheap flights from Columbus (CMH) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated January 15, 2026.

Round-trip from

$426
(KAYAK)

One-way from

$184
(KAYAK)

Popular in

December

Cheapest in

October

Average price

$569
From Columbus to Panama
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One-way flight from Columbus to Panama
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Highest demand for flights based on searches. 25% potential increase in price ($223 potential increase over avg. RT price).
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Cheapest flight prices on average. 14% potential price decrease ($79 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This KAYAK deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/179:05 am
CMH
-
PTY
2 stops10h 33m
Copa Airlines
Mon 2/234:41 pm
PTY
-
CMH
2 stops20h 34m
Copa Airlines
Deal found 1/12$426
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:07 am
CMH
-
PTY
1 stop6h 56m
Delta
Thu 4/162:20 pm
PTY
-
CMH
1 stop17h 38m
Delta
Deal found 1/13$435
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:38 am
CMH
-
PTY
1 stop8h 53m
United Airlines
Thu 4/1610:55 pm
PTY
-
CMH
2 stops15h 32m
United Airlines
Deal found 1/13$439
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:24 pm
CMH
-
PTY
1 stop19h 31m
Delta
Tue 4/212:20 pm
PTY
-
CMH
1 stop9h 15m
Delta
Deal found 1/13$442
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1511:44 am
CMH
-
PTY
1 stop29h 23m
United Airlines
Thu 2/194:41 pm
PTY
-
CMH
1 stop18h 22m
United Airlines
Deal found 1/13$444
This KAYAK deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:40 pm
CMH
-
PTY
2 stops19h 05m
Copa Airlines
Thu 2/194:41 pm
PTY
-
CMH
1 stop18h 22m
Copa Airlines
Deal found 1/13$445
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:00 am
CMH
-
PTY
2 stops12h 37m
United Airlines
Thu 7/303:20 pm
PTY
-
CMH
1 stop29h 30m
United Airlines
Deal found 1/15$448
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:49 pm
CMH
-
PTY
1 stop21h 31m
American Airlines
Fri 8/213:20 pm
PTY
-
CMH
2 stops19h 16m
American Airlines
Deal found 1/14$450
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:20 am
CMH
-
PTY
1 stop13h 17m
United Airlines
Wed 4/1510:00 am
PTY
-
CMH
1 stop11h 03m
United Airlines
Deal found 1/13$452
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:00 am
CMH
-
PTY
2 stops12h 37m
United Airlines
Mon 8/243:20 pm
PTY
-
CMH
2 stops17h 35m
United Airlines
Deal found 1/14$456
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/313:50 pm
CMH
-
PTY
1 stop22h 17m
Delta
Thu 8/62:20 pm
PTY
-
CMH
1 stop17h 38m
Delta
Deal found 1/15$460
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:05 pm
CMH
-
PTY
1 stop7h 57m
United Airlines
Sun 3/83:41 pm
PTY
-
CMH
1 stop29h 34m
United Airlines
Deal found 1/15$461

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Columbus Airport to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 5/13

11:40 am-6:37 pm

1 stop7h 57m

Panama City Tocumen Intl

Tue 5/26

10:00 am-9:50 pm

1 stop10h 50m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 3/25

11:38 am-7:02 pm

1 stop8h 24m

Panama City Tocumen Intl

Tue 3/31

3:30 pm-10:57 am

1 stop18h 27m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

6:20 am-6:37 pm

1 stop13h 17m

Panama City Tocumen Intl

Mon 4/20

7:55 am-10:03 pm

1 stop13h 08m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 3/25

6:30 am-4:07 pm

1 stop10h 37m

Panama City Tocumen Intl

Tue 4/7

10:00 am-10:03 pm

1 stop11h 03m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/8

5:40 am-4:12 pm

2 stops11h 32m

Panama City Tocumen Intl

Wed 4/15

10:00 am-11:44 pm

2 stops12h 44m

$439

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 4/13

5:40 am-4:12 pm

2 stops11h 32m

Panama City Tocumen Intl

Wed 4/15

10:00 am-11:44 pm

2 stops12h 44m

$439

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/8

11:38 am-7:31 pm

1 stop8h 53m

Panama City Tocumen Intl

Tue 4/21

10:00 am-11:44 pm

2 stops12h 44m

$439

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 2/15

7:40 pm-5:07 pm

2 stops21h 27m

Panama City Tocumen Intl

Thu 2/19

4:41 pm-9:41 am

2 stops17h 00m

$439

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 2/24

5:30 am-5:07 pm

2 stops11h 37m

Panama City Tocumen Intl

Wed 3/4

8:55 am-10:12 pm

1 stop13h 17m

$439

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Tue 2/24

12:05 pm-9:04 am

2 stops20h 59m

David Enrique Malek

Fri 2/27

9:48 am-10:12 pm

2 stops36h 24m

$891

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 20 results
1
2

Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Panama

What is the cheapest month to book a flight from Columbus Airport to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in February is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 15, 2026.
Read through reviews of airlines operating flights from Columbus Airport to Panama, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,048 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,048 reviews
Delta
7.9
Good
8,048 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,163 reviews
Delta
7.9
Good
8,048 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,129 reviews
Delta
7.9
Good
8,048 reviews

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to Panama?

    Airlines like United Airlines fly from Columbus Airport to Panama in about 7h 57m. The time it takes to get you to your destination can typically vary by up to . Columbus Airport and Panama are separated by a distance of 2146 mi.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to Panama (average of $330). Flying from Columbus Airport to Panama in February is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$359Average$534FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$632FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$593FlexibilityNo cancel feeOn-time69%

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