How long is the flight from Mississippi to Panama?

For as low as $516, United Airlines can have you in Panama from Mississippi in 6h 42m. Airlines will cover a distance of 1744 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What is the cheapest time of day to fly from MS to PA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Panama as you normally would.

Can I find deals for flights from Mississippi to Panama that include hotel bookings?

Yes. In addition to deals on Mississippi to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to Panama?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama.

Can I find deals for business class flights from Mississippi to Panama?

Yes. Cheapflights offers flight deals from Mississippi to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$232+ Cheap Flights from Mississippi to Panama

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Cheap flight deals from Mississippi to Panama

Most accurate provider	eDreams 3 stars
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Round-trip from	$463 (United Airlines)
One-way from	$232 (United Airlines)

Provider with most accurate pricing for Jackson-Evers Intl-Panama City Tocumen Intl flight deals.

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From Mississippi to Panama

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Find flight deals from Mississippi to Panama

Cheapest flights from Mississippi to Panama
Explore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

dom. 12/142:00 pmJAN - PTY

1 stop26h 07mUnited Airlines

dom. 12/218:55 amPTY - JAN

1 stop8h 07mUnited Airlines

Deal found 10/30

$483

dom. 12/144:55 pmMOB - PTY

1 stop20h 50mUnited Airlines

dom. 12/214:41 pmPTY - MOB

1 stop24h 28mUnited Airlines

Deal found 10/30

$511

sáb. 12/612:17 pmJAN - PTY

1 stop6h 42mDelta

sáb. 12/138:05 amPTY - JAN

1 stop7h 19mDelta

Deal found 10/29

$516

sáb. 12/66:31 pmJAN - PTY

2 stops18h 16mAmerican Airlines

sáb. 12/132:50 pmPTY - JAN

2 stops18h 52mAmerican Airlines

Deal found 10/29

$520

sáb. 12/66:31 pmJAN - PTY

2 stops18h 16mAmerican Airlines

dom. 12/144:43 pmPTY - JAN

2 stops19h 57mAmerican Airlines

Deal found 10/30

$525

dom. 12/141:57 pmGPT - PTY

1 stop23h 48mUnited Airlines

dom. 12/214:41 pmPTY - GPT

1 stop24h 22mUnited Airlines

Deal found 10/30

$526

sáb. 12/136:31 amMEM - PTY

1 stop7h 14mUnited Airlines

sáb. 12/204:41 pmPTY - MEM

1 stop17h 35mUnited Airlines

Deal found 10/29

$550

jue. 12/116:11 pmMEM - PTY

2 stops20h 31mAmerican Airlines

lun. 12/154:43 pmPTY - MEM

2 stops18h 54mAmerican Airlines

Deal found 10/30

$554

jue. 12/116:11 pmMEM - PTY

2 stops20h 31mAmerican Airlines

dom. 12/142:50 pmPTY - MEM

1 stop10h 09mAmerican Airlines

Deal found 10/30

$559

jue. 11/139:00 amMEM - PTY

1 stop9h 38mUnited Airlines

lun. 11/1710:00 amPTY - MEM

1 stop11h 32mUnited Airlines

Deal found 10/30

$570

lun. 11/173:47 pmMEM - PTY

2 stops21h 02mAmerican Airlines

mié. 11/192:49 pmPTY - MEM

2 stops20h 23mAmerican Airlines

Deal found 10/29

$574

jue. 11/612:00 pmJAN - PTY

1 stop6h 38mUnited Airlines

mar. 11/118:55 amPTY - JAN

1 stop8h 10mUnited Airlines

Deal found 10/29

$576

Best flights from Mississippi to Panama
Discover carefully curated flight deals from Mississippi to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated octubre 30, 2025.

mié. 2/252:03 pmJAN - PTY

1 stop26h 04mUnited Airlines

dom. 3/18:55 amPTY - JAN

1 stop14h 04mUnited Airlines

Deal found 10/28

$463

sáb. 12/612:17 pmJAN - PTY

1 stop6h 42mDelta

dom. 12/143:46 pmPTY - JAN

1 stop8h 19mDelta

Deal found 10/29

$516

sáb. 12/66:31 pmJAN - PTY

2 stops18h 16mAmerican Airlines

sáb. 12/132:50 pmPTY - JAN

2 stops18h 52mAmerican Airlines

Deal found 10/29

$520

dom. 12/142:00 pmJAN - PTY

1 stop26h 07mUnited Airlines

dom. 12/218:55 amPTY - JAN

1 stop8h 07mUnited Airlines

Deal found 10/30

$483

sáb. 12/612:17 pmJAN - PTY

1 stop6h 42mDelta

sáb. 12/138:05 amPTY - JAN

1 stop7h 19mDelta

Deal found 10/29

$516

sáb. 12/63:04 pmJAN - PTY

2 stops21h 43mAmerican Airlines

dom. 12/144:43 pmPTY - JAN

2 stops21h 38mAmerican Airlines

Deal found 10/29

$525

dom. 12/144:55 pmMOB - PTY

1 stop20h 50mUnited Airlines

dom. 12/214:41 pmPTY - MOB

1 stop24h 28mUnited Airlines

Deal found 10/30

$511

jue. 12/116:11 pmMEM - PTY

2 stops20h 31mAmerican Airlines

dom. 12/142:50 pmPTY - MEM

1 stop10h 09mAmerican Airlines

Deal found 10/30

$559

dom. 12/141:57 pmGPT - PTY

1 stop23h 48mUnited Airlines

dom. 12/214:41 pmPTY - GPT

1 stop24h 22mUnited Airlines

Deal found 10/30

$526

lun. 11/173:47 pmMEM - PTY

2 stops21h 02mAmerican Airlines

mié. 11/192:49 pmPTY - MEM

2 stops20h 23mAmerican Airlines

Deal found 10/29

$574

sáb. 12/136:31 amMEM - PTY

1 stop7h 14mUnited Airlines

sáb. 12/204:41 pmPTY - MEM

1 stop17h 35mUnited Airlines

Deal found 10/29

$550

mié. 2/256:19 amJAN - PTY

2 stops30h 21mAmerican Airlines

dom. 3/14:04 pmPTY - JAN

2 stops21h 05mAmerican Airlines

Deal found 10/28

$575

lun. 11/176:45 amMEM - PTY

1 stop7h 00mUnited Airlines

mié. 11/198:55 amPTY - MEM

1 stop12h 05mUnited Airlines

Deal found 10/29

$570

dom. 12/146:01 pmGPT - PTY

2 stops38h 19mWestJet

dom. 12/2110:20 amPTY - GPT

2 stops31h 15mWestJet

Deal found 10/30

$1,683

sáb. 12/136:11 pmMEM - PTY

2 stops20h 31mAmerican Airlines

sáb. 12/204:55 pmPTY - MEM

1 stop8h 45mAmerican Airlines

Deal found 10/29

$604

jue. 11/139:00 amMEM - PTY

1 stop9h 38mUnited Airlines

lun. 11/1710:00 amPTY - MEM

1 stop11h 32mUnited Airlines

Deal found 10/30

$570

dom. 12/146:33 pmMEM - PTY

1 stop20h 09mAmerican Airlines

dom. 12/214:55 pmPTY - MEM

1 stop8h 45mAmerican Airlines

Deal found 10/30

$609

mié. 11/1211:37 amMEM - PTY

1 stop7h 01mUnited Airlines

mar. 11/188:55 amPTY - MEM

1 stop13h 46mUnited Airlines

Deal found 10/30

$591

mar. 12/167:00 amBTR - PTY

1 stop6h 45mUnited Airlines

dom. 1/114:41 pmPTY - BTR

1 stop24h 17mUnited Airlines

Deal found 10/30

$599

dom. 11/96:13 pmBTR - PTY

2 stops18h 36mAmerican Airlines

lun. 12/12:43 pmPTY - BTR

2 stops24h 07mAmerican Airlines

Deal found 10/29

$706

sáb. 12/132:00 pmBTR - PTY

1 stop28h 38mUnited Airlines

sáb. 12/204:41 pmPTY - BTR

1 stop19h 44mUnited Airlines

Deal found 10/29

$606

sáb. 12/132:16 pmBTR - PTY

2 stops24h 26mAmerican Airlines

sáb. 12/204:55 pmPTY - BTR

2 stops17h 44mAmerican Airlines

Deal found 10/29

$712

sáb. 11/226:35 amMEM - PTY

1 stop7h 10mUnited Airlines

dom. 11/234:41 pmPTY - MEM

1 stop17h 31mUnited Airlines

Deal found 10/30

$643

dom. 12/145:27 pmBTR - PTY

2 stops21h 15mAmerican Airlines

sáb. 1/102:27 pmPTY - BTR

2 stops20h 36mAmerican Airlines

Deal found 10/29

$775

dom. 11/93:56 pmBTR - PTY

1 stop26h 42mUnited Airlines

lun. 12/14:41 pmPTY - BTR

1 stop21h 33mUnited Airlines

Deal found 10/29

$795

sáb. 12/206:45 pmMOB - PTY

2 stops18h 08mAmerican Airlines

dom. 1/42:53 pmPTY - MOB

2 stops20h 32mAmerican Airlines

Deal found 10/29

$1,126

dom. 12/1412:10 pmBTR - PTY

1 stop25h 35mUnited Airlines

sáb. 1/104:41 pmPTY - BTR

1 stop19h 44mUnited Airlines

Deal found 10/29

$970

vie. 12/195:13 amMOB - PTY

2 stops9h 41mAmerican Airlines

dom. 1/42:53 pmPTY - MOB

2 stops20h 32mAmerican Airlines

Deal found 10/29

$1,428

vie. 12/1911:40 amMOB - PTY

1 stop6h 58mUnited Airlines

dom. 1/44:41 pmPTY - MOB

1 stop20h 43mUnited Airlines

Deal found 10/30

$1,514

mar. 12/162:21 pmBTR - PTY

2 stops41h 59mWestJet

dom. 1/1110:20 amPTY - BTR

2 stops36h 43mWestJet

Deal found 10/30

$5,778

Last-minute flights from Mississippi to Panama
Discover last-minute flight deals from Mississippi to Panama. Data last updated octubre 30, 2025 and is based on user searches.

mié. 11/59:00 amMEM - PTY

1 stop9h 38mUnited Airlines

mié. 11/1210:00 amPTY - MEM

1 stop11h 32mUnited Airlines

Deal found 10/29

$591

mié. 11/56:00 amMEM - PTY

1 stop6h 49mAmerican Airlines

mié. 11/122:49 pmPTY - MEM

2 stops18h 27mAmerican Airlines

Deal found 10/29

$595

jue. 11/612:00 pmJAN - PTY

1 stop6h 38mUnited Airlines

mar. 11/118:55 amPTY - JAN

1 stop8h 10mUnited Airlines

Deal found 10/29

$576

jue. 11/63:01 pmJAN - PTY

2 stops21h 48mAmerican Airlines

mar. 11/112:49 pmPTY - JAN

2 stops21h 55mAmerican Airlines

Deal found 10/29

$580

vie. 11/77:00 amJAN - PTY

1 stop11h 38mUnited Airlines

mar. 11/118:55 amPTY - JAN

1 stop8h 10mUnited Airlines

Deal found 10/29

$596

vie. 11/74:23 pmJAN - PTY

2 stops20h 26mAmerican Airlines

mar. 11/112:49 pmPTY - JAN

2 stops21h 55mAmerican Airlines

Deal found 10/29

$600

vie. 11/712:00 pmJAN - PTY

1 stop6h 38mUnited Airlines

lun. 11/104:41 pmPTY - JAN

1 stop19h 41mUnited Airlines

Deal found 10/29

$604

vie. 11/74:23 pmJAN - PTY

2 stops20h 26mAmerican Airlines

lun. 11/102:49 pmPTY - JAN

2 stops23h 31mAmerican Airlines

Deal found 10/29

$620

vie. 11/78:55 pmMEM - PTY

3 stops27h 05mMultiple Airlines

dom. 11/99:45 amPTY - MEM

3 stops35h 15mMultiple Airlines

Deal found 10/30

$625

jue. 11/139:00 amMEM - PTY

1 stop9h 38mUnited Airlines

lun. 11/1710:00 amPTY - MEM

1 stop11h 32mUnited Airlines

Deal found 10/30

$570

jue. 11/136:47 pmMEM - PTY

2 stops18h 02mAmerican Airlines

lun. 11/172:49 pmPTY - MEM

1 stop10h 10mAmerican Airlines

Deal found 10/30

$594

lun. 11/176:11 pmMEM - PTY

2 stops18h 38mAmerican Airlines

mié. 11/192:49 pmPTY - MEM

1 stop10h 10mAmerican Airlines

Deal found 10/29

$574

One-way flights from Mississippi to Panama
Search for one-way flight options from Mississippi to Panama. Find affordable one-way fares based on user searches. Data last updated octubre 30, 2025.

jue. 12/256:30 amMEM - PTY

1 stop12h 08mUnited Airlines

Deal found 10/30

$232

jue. 12/255:12 pmMEM - PTY

2 stops21h 42mAmerican Airlines

Deal found 10/30

$470

Fly from

Fly to

Route

Depart

Return

Price

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

mié. 2/25

2:03 pm-5:07 pm

1 stop26h 04m

Panama City Tocumen Intl

dom. 3/1

8:55 am-9:59 pm

1 stop14h 04m

$463

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

dom. 12/14

2:00 pm-5:07 pm

1 stop26h 07m

Panama City Tocumen Intl

dom. 12/21

8:55 am-4:02 pm

1 stop8h 07m

$483

MobilePanama City

MOB - PTY

MOBPTY

Mobile

dom. 12/14

4:55 pm-2:45 pm

1 stop20h 50m

Panama City Tocumen Intl

dom. 12/21

4:41 pm-4:09 pm

1 stop24h 28m

$511

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

sáb. 12/6

12:17 pm-7:59 pm

1 stop6h 42m

Panama City Tocumen Intl

dom. 12/14

3:46 pm-11:05 pm

1 stop8h 19m

$516

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

sáb. 12/6

12:17 pm-7:59 pm

1 stop6h 42m

Panama City Tocumen Intl

sáb. 12/13

8:05 am-2:24 pm

1 stop7h 19m

$516

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

sáb. 12/6

6:31 pm-1:47 pm

2 stops18h 16m

Panama City Tocumen Intl

sáb. 12/13

2:50 pm-8:42 am

2 stops18h 52m

$520

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

sáb. 12/6

3:04 pm-1:47 pm

2 stops21h 43m

Panama City Tocumen Intl

dom. 12/14

4:43 pm-1:21 pm

2 stops21h 38m

$525

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

dom. 12/14

1:57 pm-2:45 pm

1 stop23h 48m

Panama City Tocumen Intl

dom. 12/21

4:41 pm-4:03 pm

1 stop24h 22m

$526

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

sáb. 12/13

6:31 am-2:45 pm

1 stop7h 14m

Panama City Tocumen Intl

sáb. 12/20

4:41 pm-9:16 am

1 stop17h 35m

$550

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

jue. 12/11

6:11 pm-3:42 pm

2 stops20h 31m

Panama City Tocumen Intl

dom. 12/14

2:50 pm-11:59 pm

1 stop10h 09m

$559

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 32 results

Best time to book a flight from Mississippi to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Panama

No data available for this route at this time. Please check back soon.

Related info for your journey

How long is the flight from Mississippi to Panama?
For as low as $516, United Airlines can have you in Panama from Mississippi in 6h 42m. Airlines will cover a distance of 1744 mi. This flight may include one or multiple stops.
Can I find deals for flights from Mississippi to Panama that include hotel bookings?
Yes. In addition to deals on Mississippi to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to Panama?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama.
Can I find deals for business class flights from Mississippi to Panama?
Yes. Cheapflights offers flight deals from Mississippi to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Mississippi to Panama

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Top airline flying from Mississippi to Panama

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$445	Average$611	FlexibilityNo cancel fee	On-time69%

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$232+ Cheap flights from Mississippi to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Mississippi to Panama

Keep the following information in mind while searching for Mississippi to Panama flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Find flight deals from Mississippi to Panama

Cheapest flights from Mississippi to PanamaExplore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

Explore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to Panama that are best for you.

Best time to book a flight from Mississippi to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Panama

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Mississippi to Panama?

Can I find deals for flights from Mississippi to Panama that include hotel bookings?

How can I find direct flights from Mississippi to Panama?

Can I find deals for business class flights from Mississippi to Panama?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Mississippi to Panama

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Cheapest flights from Mississippi to Panama
Explore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.