$239+ Cheap flights from Mississippi to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from Mississippi to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to Panama
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Cheapest flights from Mississippi to PanamaExplore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:00 pm
JAN
- PTY
1 stop6h 37m
United Airlines
Sun 8/233:20 pm
PTY
- JAN
1 stop28h 08m
United Airlines
Deal found 2/1![United Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:45 pm
JAN
- PTY
2 stops20h 35m
American Airlines
Sun 8/233:20 pm
PTY
- JAN
2 stops25h 55m
American Airlines
Deal found 2/1![American Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:55 pm
JAN
- PTY
1 stop25h 43m
United Airlines
Wed 4/13:30 pm
PTY
- JAN
1 stop24h 42m
United Airlines
Deal found 2/3![United Airlines logo]()
$492
This Gurufare deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:55 pm
JAN
- PTY
1 stop25h 43m
Copa Airlines
Thu 4/27:55 am
PTY
- JAN
1 stop8h 17m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:29 pm
GPT
- PTY
2 stops20h 11m
American Airlines
Wed 3/181:40 pm
PTY
- GPT
2 stops20h 33m
American Airlines
Deal found 2/2![American Airlines logo]()
$501
This KAYAK deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:55 pm
JAN
- PTY
1 stop25h 43m
Copa Airlines
Tue 3/313:30 pm
PTY
- JAN
1 stop21h 53m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:55 pm
MOB
- PTY
1 stop23h 17m
United Airlines
Sun 5/37:55 am
PTY
- MOB
1 stop14h 04m
United Airlines
Deal found 2/3![United Airlines logo]()
$505
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:33 pm
MOB
- PTY
2 stops18h 13m
American Airlines
Sun 5/31:49 pm
PTY
- MOB
2 stops20h 25m
American Airlines
Deal found 2/3![American Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:35 am
MEM
- PTY
1 stop7h 02m
United Airlines
Mon 4/67:55 am
PTY
- MEM
1 stop13h 45m
United Airlines
Deal found 2/3![United Airlines logo]()
$511
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:35 pm
JAN
- PTY
2 stops21h 45m
American Airlines
Tue 3/311:40 pm
PTY
- JAN
2 stops22h 17m
American Airlines
Deal found 2/3![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:55 pm
GPT
- PTY
1 stop23h 12m
United Airlines
Wed 3/183:41 pm
PTY
- GPT
1 stop21h 44m
United Airlines
Deal found 2/2![United Airlines logo]()
$512
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:55 pm
MEM
- PTY
2 stops18h 45m
American Airlines
Tue 3/313:51 pm
PTY
- MEM
2 stops16h 21m
American Airlines
Deal found 2/2![American Airlines logo]()
$515
Best flights from Mississippi to PanamaDiscover carefully curated flight deals from Mississippi to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Mississippi to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:03 pm
JAN
- PTY
1 stop28h 35m
United Airlines
Wed 4/17:55 am
PTY
- JAN
1 stop27h 16m
United Airlines
Deal found 2/1![United Airlines logo]()
$492
This Gurufare deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:55 pm
JAN
- PTY
1 stop25h 43m
Copa Airlines
Thu 4/27:55 am
PTY
- JAN
1 stop8h 17m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:33 pm
MOB
- PTY
2 stops18h 13m
American Airlines
Sun 5/31:49 pm
PTY
- MOB
2 stops20h 17m
American Airlines
Deal found 2/2![American Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:15 am
MEM
- PTY
1 stop7h 47m
Delta
Sun 5/32:27 pm
PTY
- MEM
1 stop8h 59m
Delta
Deal found 2/1![Delta logo]()
$531
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:03 pm
JAN
- PTY
1 stop28h 35m
United Airlines
Tue 3/313:30 pm
PTY
- JAN
1 stop21h 53m
United Airlines
Deal found 2/3![United Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:35 pm
JAN
- PTY
2 stops21h 45m
American Airlines
Tue 3/311:40 pm
PTY
- JAN
2 stops19h 05m
American Airlines
Deal found 2/1![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:55 pm
MOB
- PTY
1 stop21h 19m
United Airlines
Sun 5/37:55 am
PTY
- MOB
1 stop8h 15m
United Airlines
Deal found 2/1![United Airlines logo]()
$505
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:35 pm
JAN
- PTY
2 stops21h 45m
American Airlines
Wed 4/11:40 pm
PTY
- JAN
2 stops22h 17m
American Airlines
Deal found 2/1![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:00 am
MEM
- PTY
1 stop9h 37m
United Airlines
Mon 4/63:30 pm
PTY
- MEM
1 stop17h 30m
United Airlines
Deal found 2/1![United Airlines logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:54 pm
GPT
- PTY
2 stops24h 40m
Multiple Airlines
Sat 2/216:37 pm
PTY
- GPT
1 stop25h 03m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$1,247
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:59 pm
MEM
- PTY
2 stops16h 11m
American Airlines
Thu 8/63:20 pm
PTY
- MEM
1 stop8h 08m
American Airlines
Deal found 2/1![American Airlines logo]()
$535
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:15 am
MEM
- PTY
1 stop9h 52m
United Airlines
Tue 3/317:55 am
PTY
- MEM
1 stop13h 45m
United Airlines
Deal found 2/2![United Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:55 pm
GPT
- PTY
1 stop23h 12m
United Airlines
Wed 3/183:41 pm
PTY
- GPT
1 stop21h 44m
United Airlines
Deal found 2/2![United Airlines logo]()
$512
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:45 pm
MOB
- PTY
2 stops17h 55m
American Airlines
Thu 3/261:40 pm
PTY
- MOB
2 stops20h 35m
American Airlines
Deal found 2/1![American Airlines logo]()
$571
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:00 am
GPT
- PTY
1 stop6h 50m
Delta
Sat 2/213:15 pm
PTY
- GPT
1 stop19h 09m
Delta
Deal found 1/31![Delta logo]()
$763
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:00 am
MEM
- PTY
1 stop7h 12m
United Airlines
Thu 8/67:55 am
PTY
- MEM
1 stop10h 13m
United Airlines
Deal found 2/1![United Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/194:39 pm
BTR
- PTY
2 stops20h 01m
American Airlines
Thu 3/263:10 pm
PTY
- BTR
2 stops18h 44m
American Airlines
Deal found 2/1![American Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/189:00 am
MEM
- PTY
1 stop9h 38m
United Airlines
Wed 3/253:41 pm
PTY
- MEM
1 stop17h 25m
United Airlines
Deal found 2/1![United Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/144:29 pm
GPT
- PTY
2 stops21h 51m
American Airlines
Sat 3/283:10 pm
PTY
- GPT
2 stops21h 24m
American Airlines
Deal found 2/2![American Airlines logo]()
$656
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:00 am
BTR
- PTY
1 stop9h 14m
United Airlines
Tue 5/197:55 am
PTY
- BTR
1 stop11h 46m
United Airlines
Deal found 2/1![United Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:00 am
MOB
- PTY
1 stop7h 07m
United Airlines
Fri 2/278:55 am
PTY
- MOB
1 stop8h 18m
United Airlines
Deal found 1/31![United Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 am
JAN
- PTY
1 stop6h 45m
United Airlines
Fri 2/278:55 am
PTY
- JAN
1 stop8h 06m
United Airlines
Deal found 1/31![United Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/234:55 pm
GPT
- PTY
1 stop20h 50m
United Airlines
Fri 2/278:55 am
PTY
- GPT
1 stop8h 06m
United Airlines
Deal found 1/31![United Airlines logo]()
$565
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:00 am
BTR
- PTY
1 stop13h 38m
United Airlines
Thu 3/263:41 pm
PTY
- BTR
1 stop7h 04m
United Airlines
Deal found 2/1![United Airlines logo]()
$573
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:45 am
MOB
- PTY
1 stop9h 53m
United Airlines
Thu 3/263:41 pm
PTY
- MOB
1 stop24h 27m
United Airlines
Deal found 2/1![United Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/144:55 pm
GPT
- PTY
1 stop25h 43m
United Airlines
Sat 3/283:41 pm
PTY
- GPT
1 stop28h 12m
United Airlines
Deal found 2/2![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:34 am
MOB
- PTY
1 stop8h 04m
United Airlines
Fri 3/277:55 am
PTY
- MOB
1 stop11h 01m
United Airlines
Deal found 2/3![United Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/202:00 pm
GPT
- PTY
1 stop23h 45m
United Airlines
Fri 3/273:41 pm
PTY
- GPT
1 stop24h 25m
United Airlines
Deal found 2/3![United Airlines logo]()
$1,014
Last-minute flights from Mississippi to PanamaDiscover last-minute flight deals from Mississippi to Panama. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Panama. Data last updated February 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:29 pm
GPT
- PTY
2 stops20h 11m
American Airlines
Wed 3/181:40 pm
PTY
- GPT
2 stops20h 33m
American Airlines
Deal found 2/2![American Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:55 pm
GPT
- PTY
1 stop23h 12m
United Airlines
Wed 3/183:41 pm
PTY
- GPT
1 stop21h 44m
United Airlines
Deal found 2/2![United Airlines logo]()
$512
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:40 am
MEM
- PTY
1 stop6h 58m
United Airlines
Thu 3/193:41 pm
PTY
- MEM
1 stop7h 39m
United Airlines
Deal found 2/2![United Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/189:00 am
MEM
- PTY
1 stop9h 38m
United Airlines
Wed 3/253:41 pm
PTY
- MEM
1 stop17h 25m
United Airlines
Deal found 2/1![United Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:00 am
MEM
- PTY
2 stops9h 20m
American Airlines
Wed 3/251:40 pm
PTY
- MEM
1 stop10h 12m
American Airlines
Deal found 2/1![American Airlines logo]()
$535
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:00 am
MEM
- PTY
1 stop28h 45m
United Airlines
Tue 3/243:41 pm
PTY
- MEM
1 stop17h 25m
United Airlines
Deal found 2/2![United Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:15 am
MEM
- PTY
1 stop9h 52m
United Airlines
Tue 3/317:55 am
PTY
- MEM
1 stop13h 45m
United Airlines
Deal found 2/2![United Airlines logo]()
$511
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:55 pm
MEM
- PTY
2 stops18h 45m
American Airlines
Tue 3/313:51 pm
PTY
- MEM
2 stops16h 21m
American Airlines
Deal found 2/2![American Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:55 pm
JAN
- PTY
1 stop25h 43m
United Airlines
Wed 4/13:30 pm
PTY
- JAN
1 stop24h 42m
United Airlines
Deal found 2/3![United Airlines logo]()
$492
This KAYAK deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:55 pm
JAN
- PTY
1 stop25h 43m
Copa Airlines
Tue 3/313:30 pm
PTY
- JAN
1 stop21h 53m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:35 pm
JAN
- PTY
2 stops21h 45m
American Airlines
Tue 3/311:40 pm
PTY
- JAN
2 stops22h 17m
American Airlines
Deal found 2/3![American Airlines logo]()
$511
This Gurufare deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:55 pm
JAN
- PTY
1 stop25h 43m
Copa Airlines
Thu 4/27:55 am
PTY
- JAN
1 stop8h 17m
Copa Airlines
Deal found 2/3![Copa Airlines logo]()
$494
One-way flights from Mississippi to PanamaSearch for one-way flight options from Mississippi to Panama. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Mississippi to Panama. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:04 pm
MEM
- PTY
3 stops28h 36m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$239
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:15 am
MEM
- PTY
1 stop9h 57m
United Airlines
Deal found 2/1![United Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:23 pm
MEM
- PTY
2 stops19h 38m
American Airlines
Deal found 2/1![American Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:15 am
BTR
- PTY
1 stop8h 57m
United Airlines
Deal found 2/1![United Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:20 pm
BTR
- PTY
2 stops17h 50m
American Airlines
Deal found 2/2![American Airlines logo]()
$312
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:15 am
MEM
- PTY
1 stop12h 23m
United Airlines
Deal found 2/1![United Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:14 am
MEM
- PTY
3 stops46h 01m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$341
Find flight deals from Mississippi to Panama
Keep the following information in mind while searching for Mississippi to Panama flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $492 (United Airlines) |
One-way from | $239 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Mississippi to Panama that are best for you.
Fly from
Mississippi
Fly to
Panama
Route
Depart
Return
Price
JacksonPanama City
JAN - PTY
JANPTY
Jackson-Evers Intl
Thu 3/26
2:03 pm-6:38 pm
1 stop28h 35m
Panama City Tocumen Intl
Wed 4/1
7:55 am-11:11 am
1 stop27h 16m
$492
JacksonPanama City
JAN - PTY
JANPTY
Jackson-Evers Intl
Thu 3/26
2:03 pm-6:38 pm
1 stop28h 35m
Panama City Tocumen Intl
Tue 3/31
3:30 pm-1:23 pm
1 stop21h 53m
$492
JacksonPanama City
JAN - PTY
JANPTY
Jackson-Evers Intl
Fri 3/27
4:55 pm-6:38 pm
1 stop25h 43m
Panama City Tocumen Intl
Thu 4/2
7:55 am-4:12 pm
1 stop8h 17m
$494
MobilePanama City
MOB - PTY
MOBPTY
Mobile
Fri 4/24
4:55 pm-2:14 pm
1 stop21h 19m
Panama City Tocumen Intl
Sun 5/3
7:55 am-4:10 pm
1 stop8h 15m
$505
MobilePanama City
MOB - PTY
MOBPTY
Mobile
Fri 4/24
6:33 pm-12:46 pm
2 stops18h 13m
Panama City Tocumen Intl
Sun 5/3
1:49 pm-10:06 am
2 stops20h 17m
$506
JacksonPanama City
JAN - PTY
JANPTY
Jackson-Evers Intl
Thu 3/26
4:35 pm-2:20 pm
2 stops21h 45m
Panama City Tocumen Intl
Tue 3/31
1:40 pm-8:45 am
2 stops19h 05m
$511
JacksonPanama City
JAN - PTY
JANPTY
Jackson-Evers Intl
Thu 3/26
4:35 pm-2:20 pm
2 stops21h 45m
Panama City Tocumen Intl
Wed 4/1
1:40 pm-11:57 am
2 stops22h 17m
$511
MemphisPanama City
MEM - PTY
MEMPTY
Memphis
Wed 4/1
9:00 am-6:37 pm
1 stop9h 37m
Panama City Tocumen Intl
Mon 4/6
3:30 pm-9:00 am
1 stop17h 30m
$511
MemphisPanama City
MEM - PTY
MEMPTY
Memphis
Tue 3/24
6:15 am-4:07 pm
1 stop9h 52m
Panama City Tocumen Intl
Tue 3/31
7:55 am-9:40 pm
1 stop13h 45m
$511
GulfportPanama City
GPT - PTY
GPTPTY
Gulfport Biloxi Regional
Mon 3/2
4:55 pm-5:07 pm
1 stop23h 12m
Panama City Tocumen Intl
Wed 3/18
3:41 pm-1:25 pm
1 stop21h 44m
$512
Showing 1-10 of 35 results
Best time to book a flight from Mississippi to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Mississippi with our price prediction graph.
MEM-PTY
BTR-PTY
JAN-PTY
GPT-PTY
MOB-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Panama
USMS-PA0
MEM-PTY
BTR-PTY
JAN-PTY
GPT-PTY
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mississippi to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from Mississippi to Panama
Discover the top airline that operate flights from Mississippi to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$445 | Average$609 | FlexibilityNo cancel fee | On-time69% |