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$222+ Cheap flights from LaGuardia, NY (LGA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — PTY
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from LaGuardia to Panama

Cheapest flights from LaGuardia to Panama
Explore the most affordable flight options available from LaGuardia to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:59 am
LGA
-
PTY
2 stops16h 56m
Multiple Airlines
Mon 6/13:10 pm
PTY
-
LGA
2 stops26h 50m
Multiple Airlines
Deal found 4/28$484
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:30 am
LGA
-
PTY
2 stops27h 45m
Multiple Airlines
Tue 5/195:55 pm
PTY
-
LGA
3 stops28h 26m
Multiple Airlines
Deal found 4/24$488
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:55 am
LGA
-
PTY
1 stop10h 25m
Multiple Airlines
Wed 9/25:30 am
PTY
-
LGA
2 stops12h 31m
Multiple Airlines
Deal found 4/27$490
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:59 am
LGA
-
PTY
1 stop11h 38m
Multiple Airlines
Wed 6/245:30 am
PTY
-
LGA
2 stops12h 31m
Multiple Airlines
Deal found 4/26$496
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:30 am
LGA
-
PTY
2 stops35h 30m
Multiple Airlines
Tue 5/124:25 am
PTY
-
LGA
2 stops17h 52m
Multiple Airlines
Deal found 4/25$499
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:42 pm
LGA
-
PTY
3 stops28h 53m
Multiple Airlines
Fri 6/54:25 am
PTY
-
LGA
3 stops17h 56m
Multiple Airlines
Deal found 4/25$502
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:30 am
LGA
-
PTY
2 stops19h 05m
Multiple Airlines
Sun 5/175:55 pm
PTY
-
LGA
2 stops28h 22m
Multiple Airlines
Deal found 4/24$509
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:30 am
LGA
-
PTY
2 stops27h 45m
Multiple Airlines
Sun 5/175:55 pm
PTY
-
LGA
2 stops28h 22m
Multiple Airlines
Deal found 4/24$512
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:55 am
LGA
-
PTY
1 stop10h 25m
Multiple Airlines
Wed 9/25:30 am
PTY
-
LGA
2 stops12h 31m
Multiple Airlines
Deal found 4/27$513
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/79:59 am
LGA
-
PTY
2 stops15h 36m
Multiple Airlines
Wed 6/105:30 am
PTY
-
LGA
2 stops12h 30m
Multiple Airlines
Deal found 4/26$518
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
LGA
-
DAV
2 stops28h 03m
United Airlines
Thu 6/119:50 am
DAV
-
LGA
2 stops31h 57m
United Airlines
Deal found 4/24$1,086
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:10 am
LGA
-
DAV
2 stops24h 48m
United Airlines
Sun 5/179:38 am
DAV
-
LGA
2 stops25h 58m
United Airlines
Deal found 4/26$1,223

Find flight deals from LaGuardia to Panama

Keep the following information in mind while searching for LaGuardia to Panama flight deals. Data was last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$484
(Mytrip)

One-way from

$222
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$647
Provider with most accurate pricing for New York (NYC)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Panama City Tocumen Intl flights.
Search Deals
From New York LaGuardia to Panama
Search Deals
One-way flight from New York LaGuardia to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Fri 8/21

7:55 am-6:37 pm

1 stop11h 42m

Panama City Tocumen Intl

Mon 8/24

10:00 am-9:59 pm

1 stop10h 59m

$641
Quickest round-trip

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 9/29

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Tue 10/6

2:21 pm-11:41 pm

1 stop8h 20m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sun 8/2

6:00 am-2:14 pm

1 stop9h 14m

Panama City Tocumen Intl

Fri 8/14

3:30 pm-11:25 am

1 stop18h 55m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 9/23

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Sat 9/26

2:21 pm-11:50 pm

1 stop8h 29m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 7/16

6:00 am-2:14 pm

1 stop9h 14m

Panama City Tocumen Intl

Wed 7/22

7:55 am-7:04 pm

1 stop10h 09m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sun 8/30

6:00 am-1:13 pm

1 stop8h 13m

Panama City Tocumen Intl

Sun 9/13

2:21 pm-11:50 pm

1 stop8h 29m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 7/16

10:15 am-6:37 pm

1 stop9h 22m

Panama City Tocumen Intl

Tue 7/21

10:00 am-8:59 pm

1 stop9h 59m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Mon 6/1

6:00 am-6:37 pm

1 stop13h 37m

Panama City Tocumen Intl

Fri 6/5

7:55 am-8:59 pm

1 stop12h 04m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sun 8/16

7:55 pm-2:14 pm

1 stop19h 19m

Panama City Tocumen Intl

Sun 8/23

3:30 pm-11:25 am

1 stop18h 55m

$641

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Fri 5/15

6:00 am-2:14 pm

1 stop9h 14m

Panama City Tocumen Intl

Tue 5/19

7:55 am-8:57 pm

1 stop12h 02m

$641

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Showing 1-10 of 32 resultsSorted by cheapest first
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Best time to book a flight from LaGuardia to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New York LaGuardia Airport to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New York LaGuardia Airport to Panama?

    A quick flight from New York LaGuardia Airport to Panama can take about 7h 56m. United Airlines provides one of the quickest options available for as low as $641. The distance from New York LaGuardia Airport to Panama is about 2215 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from New York LaGuardia Airport to Panama?

    Most travelers choose New York LaGuardia - Panama City Tocumen Intl, New York LaGuardia - David Enrique Malek or New York LaGuardia - Panama City Marcos A. Gelabert Intl when deciding on the best route from New York LaGuardia Airport to Panama.

  • Can I find deals for flights from LaGuardia to Panama that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Panama.

  • Can I find deals for business class flights from LaGuardia to Panama?

    Yes. Cheapflights offers flight deals from LaGuardia to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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