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Panama

$179+ Cheap flights from LaGuardia, NY (LGA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — PTY
Mar 22 — Mar 291
Sun 3/22
Sun 3/29
1 adult, Economy
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Cheap flight deals from LaGuardia to Panama

Cheapest flights from LaGuardia to Panama
Explore the most affordable flight options available from LaGuardia to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:59 pm
LGA
-
PTY
2 stops26h 16m
Multiple Airlines
Mon 4/203:05 am
PTY
-
LGA
2 stops31h 59m
Multiple Airlines
Deal found 2/18$415
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:45 pm
LGA
-
PTY
2 stops18h 15m
Multiple Airlines
Mon 3/162:55 pm
PTY
-
LGA
2 stops17h 05m
Multiple Airlines
Deal found 2/19$423
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:45 pm
LGA
-
PTY
2 stops29h 15m
Multiple Airlines
Thu 3/122:55 am
PTY
-
LGA
2 stops15h 05m
Multiple Airlines
Deal found 2/17$426
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:30 pm
LGA
-
PTY
2 stops29h 30m
Multiple Airlines
Sun 3/222:55 am
PTY
-
LGA
3 stops27h 42m
Multiple Airlines
Deal found 2/17$428
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:59 am
LGA
-
PTY
2 stops12h 41m
Multiple Airlines
Thu 3/59:45 am
PTY
-
LGA
2 stops33h 15m
Multiple Airlines
Deal found 2/17$430
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:30 pm
LGA
-
PTY
2 stops18h 30m
Multiple Airlines
Mon 3/239:45 am
PTY
-
LGA
2 stops22h 15m
Multiple Airlines
Deal found 2/17$434
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:59 am
LGA
-
PTY
2 stops15h 01m
Multiple Airlines
Tue 3/172:55 pm
PTY
-
LGA
2 stops17h 05m
Multiple Airlines
Deal found 2/18$435
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:59 pm
LGA
-
PTY
2 stops21h 16m
Multiple Airlines
Mon 4/279:33 pm
PTY
-
LGA
1 stop10h 27m
Multiple Airlines
Deal found 2/18$436
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/248:45 pm
LGA
-
PTY
2 stops20h 10m
Multiple Airlines
Fri 2/279:45 am
PTY
-
LGA
2 stops33h 14m
Multiple Airlines
Deal found 2/17$442
This Avianca Connect deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:59 am
LGA
-
PTY
2 stops14h 01m
Multiple Airlines
Mon 3/92:55 pm
PTY
-
LGA
2 stops17h 05m
Multiple Airlines
Deal found 2/17$444
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:59 am
LGA
-
PTY
2 stops26h 01m
Multiple Airlines
Fri 3/62:55 am
PTY
-
LGA
2 stops16h 04m
Multiple Airlines
Deal found 2/18$445
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
LGA
-
DAV
2 stops28h 08m
United Airlines
Sun 6/219:55 am
DAV
-
LGA
2 stops36h 20m
United Airlines
Deal found 2/20$976

Find flight deals from LaGuardia to Panama

Keep the following information in mind while searching for LaGuardia to Panama flight deals. Data was last updated February 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$415
(Mytrip)

One-way from

$179
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$655
Provider with most accurate pricing for New York (NYC)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Panama City Tocumen Intl flights.
Search Deals
From New York LaGuardia to Panama
Search Deals
One-way flight from New York LaGuardia to Panama
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Panama that are best for you.

Fly from

LaGuardia

Fly to

Panama

Route

Depart

Return

Price

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 3/3

8:45 pm-2:00 pm

2 stops17h 15m

Panama City Tocumen Intl

Tue 3/10

2:55 pm-9:00 am

2 stops17h 05m

$444

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 4/22

7:59 pm-2:15 pm

2 stops19h 16m

Panama City Tocumen Intl

Sun 4/26

5:55 pm-9:00 am

2 stops14h 05m

$449

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 4/9

10:59 am-1:55 am

2 stops15h 56m

Panama City Tocumen Intl

Wed 4/15

3:10 pm-9:00 am

2 stops16h 50m

$454

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 5/7

8:00 am-1:05 am

2 stops18h 05m

Panama City Tocumen Intl

Mon 5/11

3:10 pm-8:58 am

2 stops16h 48m

$463

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 3/24

8:30 pm-8:50 am

2 stops13h 20m

Panama City Tocumen Intl

Thu 3/26

5:50 pm-9:00 am

2 stops14h 10m

$470

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 5/28

8:00 am-1:05 am

2 stops18h 05m

Panama City Tocumen Intl

Sun 5/31

5:55 pm-8:58 am

2 stops14h 03m

$482

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 5/7

8:00 am-1:05 am

2 stops18h 05m

Panama City Tocumen Intl

Sun 5/10

3:10 pm-8:58 am

2 stops16h 48m

$482

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 5/27

8:00 am-1:05 am

2 stops18h 05m

Panama City Tocumen Intl

Mon 6/1

3:10 pm-8:58 am

2 stops16h 48m

$484

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 5/28

8:00 am-1:05 am

2 stops18h 05m

Panama City Tocumen Intl

Mon 6/1

3:10 pm-8:58 am

2 stops16h 48m

$484

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 4/15

7:59 pm-2:15 pm

2 stops19h 16m

Panama City Tocumen Intl

Mon 4/20

3:10 pm-9:00 am

2 stops16h 50m

$488

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 34 results
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Best time to book a flight from LaGuardia to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New York LaGuardia Airport to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 20, 2026.
Peruse reviews from past customers who have flown with American Airlines from New York LaGuardia Airport to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,321 reviews

Boarding

7.5

Overall

7.2

Crew

8.0

Entertainment

6.9

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,321 reviews
American Airlines
7.2
Good
11,321 reviews

Boarding

7.5

Overall

7.2

Crew

8.0

Entertainment

6.9

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New York LaGuardia Airport to Panama?

    A quick flight from New York LaGuardia Airport to Panama can take about 38h 38m. United Airlines provides one of the quickest options available for as low as $1,011. The distance from New York LaGuardia Airport to Panama is about 2297 mi.

  • What are the most popular routes from New York LaGuardia Airport to Panama?

    Most travelers choose New York LaGuardia - Panama City Tocumen Intl, New York LaGuardia - David Enrique Malek or New York LaGuardia - Panama City Marcos A. Gelabert Intl when deciding on the best route from New York LaGuardia Airport to Panama.

  • Can I find deals for flights from LaGuardia to Panama that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Panama.

  • Can I find deals for business class flights from LaGuardia to Panama?

    Yes. Cheapflights offers flight deals from LaGuardia to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for LaGuardia to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from LaGuardia to Panama

Discover the top airline that operate flights from LaGuardia to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$225Average$383FlexibilityNo cancel feeOn-time71%

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