$365+ Cheap flights from LaGuardia, NY (LGA) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — PTY
Dec 15 — Dec 221
Round-trip
1 adult, Economy
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Find cheap flights from LaGuardia to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from LaGuardia to Panama
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Cheapest flights from LaGuardia to PanamaExplore the most affordable flight options available from LaGuardia to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 15, 2026.
Explore the most affordable flight options available from LaGuardia to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 15, 2026.
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:10 am -
1 stop9h 28m
Mon 12/218:55 am -
1 stop13h 49m
Deal found 11/12![United Airlines logo]()
$775
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:29 pm -
1 stop18h 44m
Mon 12/214:33 pm -
2 stops16h 27m
Deal found 11/12![American Airlines logo]()
$803
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:45 am -
1 stop11h 53m
Fri 12/188:55 am -
1 stop11h 54m
Deal found 11/11![United Airlines logo]()
$809
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop8h 13m
Thu 1/212:26 pm -
1 stop8h 49m
Deal found 11/15![American Airlines logo]()
$820
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:47 pm -
1 stop25h 51m
Sat 12/198:55 am -
1 stop11h 54m
Deal found 11/13![United Airlines logo]()
$826
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
1 stop8h 13m
Tue 12/153:13 pm -
1 stop8h 31m
Deal found 11/11![American Airlines logo]()
$832
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop8h 34m
Tue 12/153:13 pm -
1 stop8h 31m
Deal found 11/11![American Airlines logo]()
$834
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:43 pm -
1 stop21h 30m
Sat 12/194:33 pm -
1 stop20h 17m
Deal found 11/13![American Airlines logo]()
$836
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:00 pm -
1 stop18h 13m
Mon 12/212:41 pm -
1 stop8h 17m
Deal found 11/10![American Airlines logo]()
$839
Best flights from LaGuardia to PanamaDiscover carefully curated flight deals from LaGuardia to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 15, 2026.
Discover carefully curated flight deals from LaGuardia to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 15, 2026.
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/78:20 pm -
1 stop18h 25m
Mon 2/1511:35 am -
1 stop10h 04m
Deal found 11/11![United Airlines logo]()
$775
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/296:00 am -
1 stop8h 04m
Thu 2/43:29 pm -
1 stop8h 10m
Deal found 11/13![Delta logo]()
$792
This United Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/116:00 am -
1 stop13h 38m
Sat 2/2011:35 am -
1 stop9h 14m
Deal found 11/14![United Airlines logo]()
$792
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:00 am -
1 stop8h 04m
Thu 2/43:29 pm -
1 stop8h 10m
Deal found 11/12![Delta logo]()
$809
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1310:00 am -
1 stop9h 38m
Sat 2/204:41 pm -
1 stop18h 36m
Deal found 11/12![United Airlines logo]()
$795
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/266:00 am -
1 stop8h 04m
Tue 2/23:29 pm -
1 stop8h 10m
Deal found 11/12![Delta logo]()
$809
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/126:00 am -
1 stop13h 38m
Sun 2/214:41 pm -
1 stop19h 54m
Deal found 11/11![United Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/266:00 am -
1 stop13h 38m
Sun 1/318:55 am -
1 stop11h 54m
Deal found 11/15![United Airlines logo]()
$812
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2710:00 am -
1 stop9h 38m
Sun 1/318:55 am -
1 stop12h 44m
Deal found 11/12![United Airlines logo]()
$812
This United Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:45 am -
1 stop9h 27m
Mon 1/114:41 pm -
1 stop18h 45m
Deal found 11/14![United Airlines logo]()
$812
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
1 stop11h 12m
Tue 2/24:41 pm -
1 stop18h 45m
Deal found 11/12![United Airlines logo]()
$842
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1410:10 am -
1 stop9h 28m
Thu 12/174:41 pm -
1 stop18h 35m
Deal found 11/11![United Airlines logo]()
$849
Last-minute flights from LaGuardia to PanamaDiscover last-minute flight deals from LaGuardia to Panama. Data last updated November 15, 2026 and is based on user searches.
Discover last-minute flight deals from LaGuardia to Panama. Data last updated November 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop8h 34m
Tue 12/153:13 pm -
1 stop8h 31m
Deal found 11/11![American Airlines logo]()
$834
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:00 pm -
1 stop18h 13m
Mon 12/212:41 pm -
1 stop8h 17m
Deal found 11/10![American Airlines logo]()
$839
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
1 stop8h 13m
Tue 12/153:13 pm -
1 stop8h 31m
Deal found 11/11![American Airlines logo]()
$832
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:10 am -
1 stop9h 28m
Mon 12/218:55 am -
1 stop13h 49m
Deal found 11/12![United Airlines logo]()
$775
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:29 pm -
1 stop18h 44m
Mon 12/214:33 pm -
2 stops16h 27m
Deal found 11/12![American Airlines logo]()
$803
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop8h 13m
Thu 1/212:26 pm -
1 stop8h 49m
Deal found 11/15![American Airlines logo]()
$820
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:43 pm -
1 stop21h 30m
Sat 12/194:33 pm -
1 stop20h 17m
Deal found 11/13![American Airlines logo]()
$836
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:45 am -
1 stop11h 53m
Fri 12/188:55 am -
1 stop11h 54m
Deal found 11/11![United Airlines logo]()
$809
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:47 pm -
1 stop25h 51m
Sat 12/198:55 am -
1 stop11h 54m
Deal found 11/13![United Airlines logo]()
$826
One-way flights from LaGuardia to PanamaSearch for one-way flight options from LaGuardia to Panama. Find affordable one-way fares based on user searches. Data last updated November 15, 2026.
Search for one-way flight options from LaGuardia to Panama. Find affordable one-way fares based on user searches. Data last updated November 15, 2026.
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:49 am -
1 stop7h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:59 pm -
1 stop17h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/15![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:59 pm -
1 stop17h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/87:59 pm -
1 stop17h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![American Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/309:40 am -
1 stop28h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/116:00 am -
2 stops9h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/15![American Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:00 am -
3 stops31h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/175:49 am -
1 stop10h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![American Airlines logo]()
$405
This BusinessClass deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/19:09 pm -
2 stops16h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/15![GOL logo]()
$406
Find flight deals from LaGuardia to Panama
Keep the following information in mind while searching for LaGuardia to Panama flight deals. Data was last updated November 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $775 (United Airlines) |
One-way from | $365 (American Airlines) |
Popular in | December |
Cheapest in | May |
Average price | $764 |
Cheapflights Fare Finder
Customize your flight search to find flights from LaGuardia to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 15, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Fri 1/22
5:49 am-1:26 pm
1 stop7h 37m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$369
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Mon 2/1
9:09 pm-1:26 pm
2 stops16h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$411
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Thu 2/4
7:59 pm-1:26 pm
2 stops17h 27m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$411
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Sun 1/3
6:00 am-3:33 pm
2 stops9h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$419
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Mon 12/14
6:30 am-1:20 am
3 stops42h 50m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$499
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Tue 12/1
6:30 am-1:20 am
3 stops18h 50m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$544
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Mon 12/28
8:55 pm-1:33 pm
3 stops40h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$564
Quickest round-trip
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Tue 12/1
7:00 am-2:34 pm
1 stop7h 34m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$594
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Thu 12/24
6:30 am-1:33 pm
3 stops31h 03m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$617
New YorkPanama City
LGA New York LaGuardia - PTY Panama City Tocumen Intl
LGAPTY
New York LaGuardia
Tue 12/29
10:00 pm-8:24 pm
1 stop22h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$644
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from LaGuardia to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from LaGuardia with our price prediction graph.
LGA-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from New York LaGuardia Airport to Panama
LGA-PA0
LGA-PTY
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 15, 2026.
Peruse reviews from past customers who have flown with American Airlines from New York LaGuardia Airport to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Crew
7.9
Overall
7.0
Comfort
7.1
Boarding
7.4
Food
6.4
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Entertainment
6.8
Crew
7.9
Overall
7.0
Comfort
7.1
Boarding
7.4
Food
6.4
Reviews
1 / 20
10.0
ExcellentLeonardo,May 2025
JFK - BGI
Related info for your journey
Find useful and relevant information for your journey from LaGuardia to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for LaGuardia to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from LaGuardia to Panama by cabin class
Find flights from LaGuardia to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
LaGuardia and Panama flights
Browse other LaGuardia and Panama flight options. Last updated on November 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from LaGuardia to Panama
Discover the top airline that operate flights from LaGuardia to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$669 | Average$839 | FlexibilityNo cancel fee | On-time71% |