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$251+ Cheap flights from LaGuardia, NY (LGA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — PTY
Dec 12 — Dec 191
Fri 12/12
Fri 12/19
1 adult, Economy
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Cheap flight deals from LaGuardia to Panama

Keep the following information in mind while searching for LaGuardia to Panama flight deals. Data was last updated November 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$548
(Avianca Connect)

One-way from

$251
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$614
Provider with most accurate pricing for New York (NYC)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for New York (NYC)-Panama City Tocumen Intl flights.
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From New York LaGuardia to Panama
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One-way flight from New York LaGuardia to Panama
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Highest demand for flights based on searches. 5% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from LaGuardia to Panama

Cheapest flights from LaGuardia to Panama
Explore the most affordable flight options available from LaGuardia to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:59 pmLGA - PTY
1 stop12h 07mMultiple Airlines
Sun 12/1411:25 amPTY - LGA
2 stops12h 17mMultiple Airlines
Deal found 11/12$549
This Avianca Connect deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:59 pmLGA - PTY
2 stops18h 01mMultiple Airlines
Sun 12/72:55 amPTY - LGA
2 stops19h 46mMultiple Airlines
Deal found 11/10$550
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:59 pmLGA - PTY
1 stop12h 07mMultiple Airlines
Sun 12/142:55 amPTY - LGA
2 stops14h 04mMultiple Airlines
Deal found 11/10$553
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:59 amLGA - PTY
1 stop10h 21mMultiple Airlines
Sat 1/107:50 pmPTY - LGA
2 stops37h 10mMultiple Airlines
Deal found 11/9$555
This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:30 amLGA - PTY
3 stops26h 20mMultiple Airlines
Wed 11/2611:25 amPTY - LGA
2 stops11h 56mMultiple Airlines
Deal found 11/9$557
This Avianca Connect deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:55 pmLGA - PTY
2 stops24h 00mMultiple Airlines
Tue 11/189:45 amPTY - LGA
2 stops12h 50mMultiple Airlines
Deal found 11/11$559
This Avianca Connect deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:59 pmLGA - PTY
2 stops18h 01mMultiple Airlines
Sat 1/172:55 amPTY - LGA
2 stops16h 05mMultiple Airlines
Deal found 11/11$560
This Mytrip deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/69:59 amLGA - PTY
3 stops32h 56mMultiple Airlines
Sun 12/147:50 pmPTY - LGA
3 stops21h 09mMultiple Airlines
Deal found 11/10$561
This Avianca Connect deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:53 amLGA - PTY
2 stops15h 47mMultiple Airlines
Sun 11/232:55 amPTY - LGA
2 stops20h 26mMultiple Airlines
Deal found 11/10$562
This Avianca Connect deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amLGA - PTY
2 stops19h 00mMultiple Airlines
Thu 11/209:45 amPTY - LGA
2 stops13h 30mMultiple Airlines
Deal found 11/11$563
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:00 amLGA - DAV
2 stops35h 24mUnited Airlines
Sat 4/259:50 amDAV - LGA
2 stops25h 40mUnited Airlines
Deal found 11/12$1,490
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:15 amLGA - DAV
2 stops26h 54mUnited Airlines
Wed 12/179:50 amDAV - LGA
2 stops23h 18mUnited Airlines
Deal found 11/11$1,539

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from New York LaGuardia Airport to Panama that are best for you.

Fly from

LaGuardia

Fly to

Panama

Route

Depart

Return

Price

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Fri 12/5

7:59 pm-2:00 pm

2 stops18h 01m

Panama City Tocumen Intl

Sat 12/13

2:55 am-10:41 pm

2 stops19h 46m

$550

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 3/24

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 3/25

2:20 pm-11:44 pm

1 stop8h 24m

$562

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Mon 5/4

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Fri 5/8

2:20 pm-11:50 pm

1 stop8h 30m

$562

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sat 4/25

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sat 5/9

2:20 pm-11:50 pm

1 stop8h 30m

$562

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 12/11

7:59 pm-2:00 pm

2 stops18h 01m

Panama City Tocumen Intl

Sat 12/13

2:55 am-10:41 pm

2 stops19h 46m

$565

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Mon 2/9

8:49 pm-2:00 pm

2 stops17h 11m

Panama City Tocumen Intl

Mon 2/16

2:55 pm-9:00 am

2 stops18h 05m

$566

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 1/7

8:00 pm-1:55 pm

1 stop17h 55m

Panama City Tocumen Intl

Wed 1/14

3:20 pm-8:48 am

1 stop17h 28m

$583

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Mon 2/2

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 2/4

3:20 pm-11:42 pm

1 stop8h 22m

$583

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 2/19

8:45 pm-2:00 pm

2 stops17h 15m

Panama City Tocumen Intl

Sun 2/22

5:50 pm-9:00 am

2 stops15h 10m

$584

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Fri 12/5

7:32 am-12:40 am

2 stops17h 08m

Panama City Tocumen Intl

Fri 12/5

2:55 am-8:00 pm

2 stops17h 05m

$603

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 38 results
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Best time to book a flight from LaGuardia to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New York LaGuardia Airport to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 12, 2025.
Peruse reviews from past customers who have flown with American Airlines from New York LaGuardia Airport to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Comfort

7.2

Food

6.4

Entertainment

6.9

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Comfort

7.2

Food

6.4

Entertainment

6.9

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New York LaGuardia Airport to Panama?

    A quick flight from New York LaGuardia Airport to Panama can take about 7h 55m. Delta provides one of the quickest options available for as low as $562. The distance from New York LaGuardia Airport to Panama is about 2215 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from New York LaGuardia Airport to Panama?

    Most travelers choose New York LaGuardia - Panama City Tocumen Intl, New York LaGuardia - David Enrique Malek or New York LaGuardia - Panama City Marcos A. Gelabert Intl when deciding on the best route from New York LaGuardia Airport to Panama.

  • Can I find deals for flights from LaGuardia to Panama that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Panama.

  • Can I find deals for business class flights from LaGuardia to Panama?

    Yes. Cheapflights offers flight deals from LaGuardia to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for LaGuardia to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from LaGuardia to Panama

Discover the top airline that operate flights from LaGuardia to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$225Average$446FlexibilityNo cancel feeOn-time71%

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