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$255+ Cheap flights from LaGuardia, NY (LGA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — PTY
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from LaGuardia to Panama

Keep the following information in mind while searching for LaGuardia to Panama flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$551
(Mytrip)

One-way from

$255
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$566
Provider with most accurate pricing for New York (NYC)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for New York (NYC)-Panama City Tocumen Intl flights.
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From New York LaGuardia to Panama
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One-way flight from New York LaGuardia to Panama
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Highest demand for flights based on searches. 3% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from LaGuardia to Panama

Cheapest flights from LaGuardia to Panama
Explore the most affordable flight options available from LaGuardia to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:55 pmLGA - PTY
1 stop13h 11mMultiple Airlines
Mon 11/1710:47 amPTY - LGA
1 stop11h 48mMultiple Airlines
Deal found 11/5$550
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:00 amLGA - PTY
2 stops19h 00mMultiple Airlines
Tue 12/92:55 amPTY - LGA
3 stops20h 47mMultiple Airlines
Deal found 11/4$551
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:59 amLGA - PTY
3 stops24h 31mMultiple Airlines
Sat 12/1311:25 amPTY - LGA
2 stops12h 17mMultiple Airlines
Deal found 11/4$554
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/79:59 amLGA - PTY
1 stop9h 21mMultiple Airlines
Thu 12/119:34 amPTY - LGA
2 stops13h 07mMultiple Airlines
Deal found 11/3$559
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:59 amLGA - PTY
1 stop10h 38mMultiple Airlines
Tue 12/911:25 amPTY - LGA
2 stops11h 16mMultiple Airlines
Deal found 11/5$561
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:59 pmLGA - PTY
2 stops18h 01mMultiple Airlines
Thu 12/47:50 pmPTY - LGA
3 stops26h 10mMultiple Airlines
Deal found 11/3$562
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:55 pmLGA - PTY
2 stops19h 05mMultiple Airlines
Wed 11/1911:25 amPTY - LGA
2 stops11h 56mMultiple Airlines
Deal found 11/4$563
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:32 amLGA - PTY
3 stops33h 23mMultiple Airlines
Wed 12/1011:25 amPTY - LGA
2 stops12h 17mMultiple Airlines
Deal found 11/4$565
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:30 pmLGA - PTY
2 stops12h 20mMultiple Airlines
Thu 11/2710:47 amPTY - LGA
1 stop8h 48mMultiple Airlines
Deal found 11/5$566
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:59 pmLGA - PTY
2 stops12h 51mMultiple Airlines
Sun 11/237:50 pmPTY - LGA
3 stops27h 25mMultiple Airlines
Deal found 11/5$568
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/287:59 pmLGA - PTY
1 stop12h 07mMultiple Airlines
Sat 12/68:25 amPTY - LGA
1 stop8h 34mMultiple Airlines
Deal found 11/5$569
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:15 pmLGA - DAV
3 stops23h 09mUnited Airlines
Thu 12/119:50 amDAV - LGA
2 stops33h 17mUnited Airlines
Deal found 11/4$1,064

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from New York LaGuardia Airport to Panama that are best for you.

Fly from

LaGuardia

Fly to

Panama

Route

Depart

Return

Price

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 3/24

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 3/25

2:20 pm-9:45 am

1 stop18h 25m

$562

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 5/5

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sat 5/9

2:20 pm-11:50 pm

1 stop8h 30m

$562

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Mon 5/4

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Fri 5/8

2:20 pm-11:50 pm

1 stop8h 30m

$562

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sat 4/25

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sat 5/9

2:20 pm-11:50 pm

1 stop8h 30m

$562

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sun 3/29

8:00 am-12:55 pm

1 stop29h 55m

Panama City Tocumen Intl

Tue 3/31

2:20 pm-8:46 am

1 stop17h 26m

$572

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 12/3

7:59 pm-2:00 pm

2 stops18h 01m

Panama City Tocumen Intl

Sat 12/6

2:55 am-10:41 pm

2 stops19h 46m

$573

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 1/21

7:29 pm-1:27 pm

1 stop17h 58m

Panama City Tocumen Intl

Mon 1/26

4:50 pm-10:00 am

1 stop17h 10m

$583

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Thu 12/4

9:59 am-8:37 pm

1 stop10h 38m

Panama City Tocumen Intl

Sun 12/7

9:33 pm-12:04 pm

1 stop14h 31m

$589

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 2/11

10:59 am-10:30 am

3 stops23h 31m

Panama City Tocumen Intl

Mon 2/16

9:45 am-5:03 pm

3 stops31h 18m

$592

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Mon 12/1

7:59 pm-2:00 pm

2 stops18h 01m

Panama City Tocumen Intl

Sun 12/7

2:55 am-10:41 pm

2 stops19h 46m

$604

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 34 results
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Best time to book a flight from LaGuardia to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New York LaGuardia Airport to Panama

What is the cheapest month to book a flight from New York LaGuardia Airport to Panama?

Currently, July is the cheapest month in which you can book a flight from New York LaGuardia Airport to Panama (average of $201). Flying from New York LaGuardia Airport to Panama in December is currently the most expensive (average of $1,185). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 6, 2025.
Peruse reviews from past customers who have flown with American Airlines from New York LaGuardia Airport to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,042 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,042 reviews
American Airlines
7.2
Good
11,042 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New York LaGuardia Airport to Panama?

    A quick flight from New York LaGuardia Airport to Panama can take about 7h 55m. Delta provides one of the quickest options available for as low as $562. The distance from New York LaGuardia Airport to Panama is about 2215 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from New York LaGuardia Airport to Panama?

    Most travelers choose New York LaGuardia - Panama City Tocumen Intl, New York LaGuardia - David Enrique Malek or New York LaGuardia - Panama City Marcos A. Gelabert Intl when deciding on the best route from New York LaGuardia Airport to Panama.

  • Can I find deals for flights from LaGuardia to Panama that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Panama.

  • Can I find deals for business class flights from LaGuardia to Panama?

    Yes. Cheapflights offers flight deals from LaGuardia to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New York LaGuardia Airport to Panama?

    Currently, July is the cheapest month in which you can book a flight from New York LaGuardia Airport to Panama (average of $201). Flying from New York LaGuardia Airport to Panama in December is currently the most expensive (average of $1,185). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for LaGuardia to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from LaGuardia to Panama

Discover the top airline that operate flights from LaGuardia to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$225Average$446FlexibilityNo cancel feeOn-time71%

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