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$215+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Detroit to Panama

Keep the following information in mind while searching for Detroit to Panama flight deals. Data was last updated June 12, 2025.

Round-trip from

$468
(Avianca Connect)

One-way from

$215
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$783
From Detroit Metropolitan Wayne County to Panama
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One-way flight from Detroit Metropolitan Wayne County to Panama
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Highest demand for flights based on searches. 9% potential increase in price ($91 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($52 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Detroit to Panama

Cheapest flights from Detroit to Panama
Explore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Avianca Connect deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:40 amDTW - PTY
2 stops16h 30mMultiple Airlines
Mon 10/63:25 amPTY - DTW
2 stops15h 09mMultiple Airlines
Deal found 6/11$468
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:26 pmDTW - PTY
1 stop17h 29mDelta
Thu 1/83:27 pmPTY - DTW
1 stop16h 35mDelta
Deal found 6/11$570
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:57 pmDTW - PTY
2 stops19h 28mAmerican Airlines
Fri 12/122:45 pmPTY - DTW
1 stop7h 59mAmerican Airlines
Deal found 6/11$603
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amDTW - PTY
2 stops13h 38mUnited Airlines
Sat 11/88:55 amPTY - DTW
2 stops14h 40mUnited Airlines
Deal found 6/10$683
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/176:00 amDTW - PTY
1 stop15h 34mCopa Airlines
Sun 7/2010:29 pmPTY - DTW
1 stop10h 44mCopa Airlines
Deal found 6/10$1,395

Cheapflights Fare Finder

Customize your flight search to find flights from Detroit to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama that are best for you.

Fly from

Detroit

Fly to

Panama

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/3

5:40 am-9:10 pm

2 stops16h 30m

Panama City Tocumen Intl

Mon 10/6

3:25 am-7:34 pm

2 stops15h 09m

$468

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 12/5

7:57 pm-3:25 pm

2 stops19h 28m

Panama City Tocumen Intl

Fri 12/12

2:45 pm-9:14 am

2 stops18h 29m

$603

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 11/1

6:00 am-6:38 pm

2 stops13h 38m

Panama City Tocumen Intl

Sat 11/8

8:55 am-11:35 pm

2 stops14h 40m

$683

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/18

5:20 am-12:49 pm

1 stop8h 29m

Panama City Tocumen Intl

Tue 9/23

2:14 pm-12:28 am

1 stop9h 14m

$703

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 8/2

7:48 pm-6:13 am

1 stop11h 25m

Panama City Tocumen Intl

Thu 8/7

7:55 am-10:05 pm

1 stop13h 10m

$813

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 7/26

5:26 pm-9:10 pm

3 stops28h 44m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Detroit to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama?

Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama (average of $478). Flying from Detroit Metropolitan Wayne County Airport to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to PA?

Find hourly flight availability from Detroit to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Detroit Metropolitan Wayne County Airport to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Panama?

    Detroit Metropolitan Wayne County (DTW) is the airport you will fly out of if you book a flight from Detroit to Panama. It is only a 17.3 mi journey to Detroit Metropolitan Wayne County (DTW) from Detroit’s city center.

  • Can I find deals for flights from Detroit to Panama that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama.

  • Can I find deals for business class flights from Detroit to Panama?

    Yes. Cheapflights offers flight deals from Detroit to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama?

    Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama (average of $478). Flying from Detroit Metropolitan Wayne County Airport to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Detroit to Panama

Discover the top 3 airlines that operate flights from Detroit to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$608Average$839FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$856FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$628Average$800FlexibilityNo cancel feeOn-time71%

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