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$215+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Jan 13 — Jan 201
Tue 1/13
Tue 1/20
1 adult, Economy
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Cheap flight deals from Detroit to Panama

Cheapest flights from Detroit to Panama
Explore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

This Mytrip deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:20 amDTW - PTY
2 stops18h 20mMultiple Airlines
Sat 1/107:50 pmPTY - DTW
3 stops28h 09mMultiple Airlines
Deal found 12/12$794
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:49 pmDTW - PTY
2 stops31h 11mMultiple Airlines
Tue 12/309:33 pmPTY - DTW
1 stop27h 09mMultiple Airlines
Deal found 12/13$863
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:00 amDTW - PTY
1 stop10h 00mDelta
Thu 1/18:00 amPTY - DTW
1 stop16h 52mDelta
Deal found 12/13$954
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amDTW - PTY
1 stop14h 19mMultiple Airlines
Thu 12/2511:25 amPTY - DTW
2 stops12h 34mMultiple Airlines
Deal found 12/13$964
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amDTW - PTY
1 stop11h 07mUnited Airlines
Thu 12/2511:35 amPTY - DTW
1 stop12h 08mUnited Airlines
Deal found 12/13$1,014
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:25 pmDTW - PTY
2 stops20h 29mAmerican Airlines
Thu 12/252:53 pmPTY - DTW
1 stop9h 04mAmerican Airlines
Deal found 12/13$1,018
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:58 pmDTW - PTY
2 stops19h 56mAmerican Airlines
Fri 12/262:53 pmPTY - DTW
2 stops18h 37mAmerican Airlines
Deal found 12/12$1,021

Find flight deals from Detroit to Panama

Keep the following information in mind while searching for Detroit to Panama flight deals. Data was last updated December 14, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$494
(Avianca Connect)

One-way from

$215
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$1,354
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
Search Deals
From Detroit Metropolitan Wayne County to Panama
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Panama
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($179 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($54 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama that are best for you.

Fly from

Detroit

Fly to

Panama

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 1/20

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Mon 2/2

2:55 am-10:44 pm

2 stops19h 49m

$504

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 1/28

5:15 am-12:40 am

2 stops19h 25m

Panama City Tocumen Intl

Tue 2/3

2:55 am-10:44 pm

2 stops19h 49m

$525

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 1/19

6:35 am-12:40 am

2 stops18h 05m

Panama City Tocumen Intl

Mon 1/26

2:55 am-10:44 pm

2 stops19h 49m

$531

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 1/18

12:30 pm-8:37 pm

1 stop8h 07m

Panama City Tocumen Intl

Thu 1/29

5:50 pm-12:01 pm

2 stops18h 11m

$548

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 1/16

4:21 pm-8:06 am

1 stop15h 45m

Panama City Tocumen Intl

Sun 1/25

5:50 pm-11:16 am

2 stops17h 26m

$560

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/16

12:22 pm-7:20 pm

1 stop7h 58m

Panama City Tocumen Intl

Sun 3/22

7:50 pm-6:06 pm

2 stops21h 16m

$624

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 1/19

12:30 pm-8:37 pm

1 stop8h 07m

Panama City Tocumen Intl

Sat 1/24

11:25 am-11:59 pm

2 stops12h 34m

$635

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/19

12:22 pm-8:37 pm

1 stop9h 15m

Panama City Tocumen Intl

Sun 3/22

2:55 am-12:13 am

2 stops20h 18m

$639

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 3/14

6:00 am-4:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Sun 3/22

10:55 pm-10:54 am

1 stop10h 59m

$659

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 3/11

6:00 am-2:22 pm

1 stop9h 22m

Panama City Tocumen Intl

Sat 3/21

1:44 pm-1:41 pm

2 stops22h 57m

$661

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 17 results
1
2

Best time to book a flight from Detroit to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama?

Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama (average of $592). Flying from Detroit Metropolitan Wayne County Airport to Panama in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to PA?

Find hourly flight availability from Detroit to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 14, 2025.

It’s typically best to fly out from Detroit Metropolitan Wayne County Airport to Panama at noon. Doing so could potentially save you 71% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 14, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Detroit Metropolitan Wayne County Airport to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Panama?

    Detroit Metropolitan Wayne County (DTW) is the airport you will fly out of if you book a flight from Detroit to Panama. It is only a 17.3 mi journey to Detroit Metropolitan Wayne County (DTW) from Detroit’s city center.

  • Can I find deals for flights from Detroit to Panama that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama.

  • Can I find deals for business class flights from Detroit to Panama?

    Yes. Cheapflights offers flight deals from Detroit to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama?

    Currently, June is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama (average of $592). Flying from Detroit Metropolitan Wayne County Airport to Panama in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Panama

Discover the top 3 airlines that operate flights from Detroit to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$803FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$811FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$958FlexibilityNo cancel feeOn-timeN/A

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