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$178+ Cheap flights from Charlotte (CLT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Charlotte to Panama

Cheapest flights from Charlotte to Panama
Explore the most affordable flight options available from Charlotte to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Avianca Connect deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:00 am
CLT
-
PTY
2 stops18h 00m
Multiple Airlines
Mon 2/235:50 pm
PTY
-
CLT
2 stops18h 30m
Multiple Airlines
Deal found 1/21$450
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:00 am
CLT
-
PTY
2 stops19h 00m
Multiple Airlines
Mon 3/165:50 pm
PTY
-
CLT
2 stops17h 29m
Multiple Airlines
Deal found 1/20$451
This Avianca Connect deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/227:00 am
CLT
-
PTY
2 stops18h 00m
Multiple Airlines
Thu 1/292:55 pm
PTY
-
CLT
2 stops21h 27m
Multiple Airlines
Deal found 1/21$454
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:00 am
CLT
-
PTY
2 stops17h 40m
Multiple Airlines
Mon 3/162:55 pm
PTY
-
CLT
2 stops20h 24m
Multiple Airlines
Deal found 1/20$455
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:00 am
CLT
-
PTY
2 stops17h 40m
Multiple Airlines
Sun 3/85:50 pm
PTY
-
CLT
2 stops17h 30m
Multiple Airlines
Deal found 1/20$456
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:00 am
CLT
-
PTY
2 stops19h 00m
Multiple Airlines
Tue 3/175:50 pm
PTY
-
CLT
2 stops17h 29m
Multiple Airlines
Deal found 1/20$457
This Avianca Connect deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:00 am
CLT
-
PTY
2 stops18h 40m
Multiple Airlines
Fri 3/205:50 pm
PTY
-
CLT
2 stops17h 29m
Multiple Airlines
Deal found 1/19$465
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:12 am
CLT
-
PTY
2 stops13h 48m
Multiple Airlines
Fri 3/62:55 am
PTY
-
CLT
2 stops13h 59m
Multiple Airlines
Deal found 1/20$468
This Avianca Connect deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:00 am
CLT
-
PTY
2 stops19h 00m
Multiple Airlines
Sat 3/215:50 pm
PTY
-
CLT
2 stops17h 29m
Multiple Airlines
Deal found 1/21$471
This Avianca Connect deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/256:00 am
CLT
-
PTY
2 stops19h 00m
Multiple Airlines
Sun 2/85:50 pm
PTY
-
CLT
2 stops18h 32m
Multiple Airlines
Deal found 1/19$477
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:25 pm
CLT
-
PTY
1 stop10h 39m
United Airlines
Mon 4/2710:55 pm
PTY
-
CLT
1 stop9h 08m
United Airlines
Deal found 1/20$480
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
CLT
-
PTY
2 stops19h 10m
Multiple Airlines
Fri 4/243:25 am
PTY
-
CLT
2 stops16h 04m
Multiple Airlines
Deal found 1/20$486

Find flight deals from Charlotte to Panama

Keep the following information in mind while searching for Charlotte to Panama flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$450
(Avianca Connect)

One-way from

$178
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$633
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
Search Deals
From Charlotte Douglas to Panama
Search Deals
One-way flight from Charlotte Douglas to Panama
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($76 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Charlotte

Fly to

Panama

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 2/19

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Mon 2/23

5:50 pm-12:20 pm

2 stops18h 30m

$450

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 4/11

7:00 am-9:10 pm

2 stops15h 10m

Panama City Tocumen Intl

Fri 4/17

3:25 am-8:29 pm

2 stops16h 04m

$454

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 3/16

7:00 am-12:40 am

2 stops18h 40m

Panama City Tocumen Intl

Fri 3/20

5:50 pm-12:19 pm

2 stops17h 29m

$465

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 3/3

11:12 am-1:00 am

2 stops13h 48m

Panama City Tocumen Intl

Fri 3/6

2:55 am-4:54 pm

2 stops13h 59m

$468

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 4/22

6:45 am-6:37 pm

1 stop12h 52m

Panama City Tocumen Intl

Mon 4/27

10:00 am-9:41 pm

1 stop10h 41m

$480

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/23

11:09 am-7:31 pm

1 stop9h 22m

Panama City Tocumen Intl

Tue 4/28

10:00 am-9:41 pm

1 stop10h 41m

$480

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 4/21

11:39 am-6:37 pm

1 stop7h 58m

Panama City Tocumen Intl

Mon 4/27

10:00 am-9:41 pm

1 stop10h 41m

$480

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 4/21

6:00 am-12:10 am

2 stops19h 10m

Panama City Tocumen Intl

Fri 4/24

3:25 am-8:29 pm

2 stops16h 04m

$486

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 5/3

6:00 am-12:10 am

2 stops19h 10m

Panama City Tocumen Intl

Sat 5/23

5:30 am-8:29 pm

2 stops13h 59m

$487

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 4/10

6:00 am-12:45 am

2 stops19h 45m

Panama City Tocumen Intl

Mon 4/13

3:25 am-8:23 pm

2 stops15h 58m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 18 results
1
2

Best time to book a flight from Charlotte to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Panama

What is the cheapest month to book a flight from Charlotte to Panama?

Currently, August is the cheapest month in which you can book a flight from Charlotte to Panama (average of $234). Flying from Charlotte to Panama in December is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 21, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charlotte to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,089 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,089 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,191 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,089 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charlotte to Panama?

    If you book a flight to Panama from Charlotte, you will be flying from Douglas, which is the city’s only airport. Charlotte Douglas (CLT) is located 5.7 mi from the center of Charlotte.

  • How long is the flight from Charlotte to Panama?

    A quick flight from Charlotte to Panama can take about 12h 52m. United Airlines provides one of the quickest options available for as low as $480. Airlines will cover a distance of 1808 mi.

  • Can I find deals for flights from Charlotte to Panama that include hotel bookings?

    Yes. In addition to deals on Charlotte to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Panama.

  • Can I find deals for business class flights from Charlotte to Panama?

    Yes. Cheapflights offers flight deals from Charlotte to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Panama?

    Currently, August is the cheapest month in which you can book a flight from Charlotte to Panama (average of $234). Flying from Charlotte to Panama in December is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Charlotte to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Raleigh to San José flights
Norfolk to Panama City flights
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Norfolk to San José flights
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Asheville to Liberia flights
Asheville to Philip S.W.Goldson flights
Greensboro to Liberia flights
Knoxville to Liberia flights
Asheville to Guatemala City flights
Asheville to San Salvador flights
Myrtle Beach to San José flights
Greensboro to Philip S.W.Goldson flights
Charlotte to Managua flights
Knoxville to San Salvador flights
Blountville to San José flights
Norfolk to San Salvador flights
Knoxville to Guatemala City flights
Blountville to Panama City flights
Knoxville to Philip S.W.Goldson flights
Norfolk to Managua flights
Norfolk to Coxen Hole flights

Top 3 airlines flying from Charlotte to Panama

Discover the top 3 airlines that operate flights from Charlotte to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$435Average$566FlexibilityNo cancel feeOn-time71%
DeltaCheapest$447Average$577FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$467Average$547FlexibilityNo cancel feeOn-time69%

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