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$225+ Cheap flights from Charlotte (CLT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Charlotte to Panama

Keep the following information in mind while searching for Charlotte to Panama flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$447
(Delta)

One-way from

$225
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$511
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
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From Charlotte Douglas to Panama
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One-way flight from Charlotte Douglas to Panama
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Highest demand for flights based on searches. 16% potential increase in price ($114 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Charlotte to Panama

Cheapest flights from Charlotte to Panama
Explore the most affordable flight options available from Charlotte to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2811:47 amCLT - PTY
1 stop7h 50mUnited Airlines
Wed 7/307:55 amPTY - CLT
1 stop13h 02mUnited Airlines
Deal found 4/29$447
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/59:02 amCLT - PTY
1 stop8h 24mMultiple Airlines
Wed 6/116:32 pmPTY - CLT
1 stop12h 45mMultiple Airlines
Deal found 4/29$449
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/275:58 pmCLT - PTY
1 stop20h 05mDelta
Thu 7/312:23 pmPTY - CLT
1 stop8h 35mDelta
Deal found 4/29$454
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/288:15 pmCLT - PTY
1 stop19h 05mAmerican Airlines
Wed 9/31:50 pmPTY - CLT
1 stop20h 50mAmerican Airlines
Deal found 4/28$459
This Avianca deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/46:00 amCLT - PTY
2 stops19h 10mAvianca
Sat 5/105:25 pmPTY - CLT
2 stops15h 20mAvianca
Deal found 4/29$922

Cheapflights Fare Finder

Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Charlotte

Fly to

Panama

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 7/28

6:52 am-1:03 pm

1 stop7h 11m

Panama City Tocumen Intl

Tue 7/29

2:23 pm-8:56 am

1 stop17h 33m

$447

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 6/5

9:02 am-4:26 pm

1 stop8h 24m

Panama City Tocumen Intl

Wed 6/11

6:32 pm-8:17 am

1 stop12h 45m

$449

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 7/25

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Wed 7/30

7:55 am-9:57 pm

1 stop13h 02m

$467

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 6/6

5:17 am-1:00 pm

1 stop8h 43m

Panama City Tocumen Intl

Tue 6/10

1:50 pm-6:35 am

2 stops15h 45m

$492

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 5/4

6:00 am-12:10 am

2 stops19h 10m

Panama City Tocumen Intl

Sat 5/10

5:25 pm-9:45 am

2 stops15h 20m

$922

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 5/23

9:02 pm-7:50 am

2 stops35h 48m

$225

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 5/23

6:00 am-12:19 pm

1 stop7h 19m

$281

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 5/5

5:30 pm-2:14 pm

2 stops21h 44m

$301

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 5/3

6:00 am-12:55 pm

1 stop7h 55m

$321

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Best time to book a flight from Charlotte to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Panama

What is the cheapest month to book a flight from Charlotte to Panama?

Currently, October is the cheapest month in which you can book a flight from Charlotte to Panama (average of $478). Flying from Charlotte to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to PA?

Find hourly flight availability from Charlotte to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charlotte to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 1, 2025.
To help decide which airline to fly from Charlotte to Panama, see what other customers have to say about Delta, United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charlotte to Panama?

    If you book a flight to Panama from Charlotte, you will be flying from Douglas, which is the city’s only airport. Charlotte Douglas (CLT) is located 5.7 mi from the center of Charlotte.

  • What are the cheapest airlines to fly from Charlotte to Panama one-way?

    One-way options have recently been found by users for as low as $281 on American Airlines. Other airlines that offer cheap prices include United Airlines from $301 and Delta from $321 one-way.

  • Can I find deals for flights from Charlotte to Panama that include hotel bookings?

    Yes. In addition to deals on Charlotte to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Panama.

  • Can I find deals for business class flights from Charlotte to Panama?

    Yes. Cheapflights offers flight deals from Charlotte to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Panama?

    Currently, October is the cheapest month in which you can book a flight from Charlotte to Panama (average of $478). Flying from Charlotte to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charlotte to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Knoxville to Coxen Hole flights
Blountville to San José flights
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Fayetteville to Panama City flights
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Fayetteville to San Salvador flights

Top 3 airlines flying from Charlotte to Panama

Discover the top 3 airlines that operate flights from Charlotte to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$436Average$526FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$438Average$577FlexibilityNo cancel feeOn-time71%
DeltaCheapest$453Average$565FlexibilityNo cancel feeOn-timeN/A

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