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$174+ Cheap flights from Charlotte (CLT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Apr 13 — Apr 201
Mon 4/13
Mon 4/20
1 adult, Economy
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Cheap flight deals from Charlotte to Panama

Cheapest flights from Charlotte to Panama
Explore the most affordable flight options available from Charlotte to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This Trip.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:30 am
CLT
-
PTY
2 stops19h 05m
Multiple Airlines
Sun 4/263:10 pm
PTY
-
CLT
2 stops19h 35m
Multiple Airlines
Deal found 3/11$403
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:55 am
CLT
-
PTY
1 stop9h 25m
Multiple Airlines
Wed 4/83:41 pm
PTY
-
CLT
1 stop7h 44m
Multiple Airlines
Deal found 3/9$419
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
CLT
-
PTY
1 stop10h 54m
Multiple Airlines
Sun 4/269:33 pm
PTY
-
CLT
1 stop13h 12m
Multiple Airlines
Deal found 3/13$428
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:47 pm
CLT
-
PTY
1 stop11h 19m
Multiple Airlines
Mon 4/69:33 pm
PTY
-
CLT
1 stop13h 34m
Multiple Airlines
Deal found 3/9$431
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:55 am
CLT
-
PTY
1 stop9h 25m
Multiple Airlines
Wed 4/159:33 pm
PTY
-
CLT
1 stop13h 12m
Multiple Airlines
Deal found 3/13$433
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:28 pm
CLT
-
PTY
1 stop7h 07m
Multiple Airlines
Sun 4/199:33 pm
PTY
-
CLT
1 stop13h 12m
Multiple Airlines
Deal found 3/12$435
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:00 am
CLT
-
PTY
1 stop14h 37m
Multiple Airlines
Sat 4/43:41 pm
PTY
-
CLT
1 stop8h 12m
Multiple Airlines
Deal found 3/9$436
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:42 pm
CLT
-
PTY
1 stop12h 24m
Multiple Airlines
Sun 4/199:33 pm
PTY
-
CLT
1 stop13h 12m
Multiple Airlines
Deal found 3/10$442
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:00 am
CLT
-
PTY
1 stop13h 20m
Multiple Airlines
Sat 4/43:41 pm
PTY
-
CLT
1 stop8h 12m
Multiple Airlines
Deal found 3/8$443
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:10 am
CLT
-
PTY
1 stop7h 36m
American Airlines
Wed 5/61:49 pm
PTY
-
CLT
1 stop9h 10m
American Airlines
Deal found 3/9$449

Find flight deals from Charlotte to Panama

Keep the following information in mind while searching for Charlotte to Panama flight deals. Data was last updated March 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$403
(Trip.com)

One-way from

$174
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$577
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
Search Deals
From Charlotte Douglas to Panama
Search Deals
One-way flight from Charlotte Douglas to Panama
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 4/17

6:30 am-12:35 am

2 stops19h 05m

Panama City Tocumen Intl

Sun 4/26

5:30 am-11:45 am

3 stops29h 15m

$428

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 3/28

10:17 am-9:15 am

2 stops23h 58m

Panama City Tocumen Intl

Fri 4/3

3:05 am-12:53 am

2 stops20h 48m

$498

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 5/28

6:30 am-1:55 am

3 stops20h 25m

Panama City Tocumen Intl

Thu 6/11

6:15 pm-11:45 am

1 stop16h 30m

$548

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 5/30

4:45 pm-1:55 am

3 stops34h 10m

Panama City Tocumen Intl

Wed 6/3

9:33 pm-11:45 am

1 stop13h 12m

$576
Quickest round-trip

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 6/9

2:44 pm-8:37 pm

1 stop6h 53m

Panama City Tocumen Intl

Sun 6/14

9:33 pm-9:17 am

1 stop10h 44m

$613

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 5/23

10:39 pm-12:13 pm

1 stop14h 34m

Panama City Tocumen Intl

Sat 5/30

1:14 pm-8:34 am

1 stop18h 20m

$627

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 6/15

10:29 pm-12:13 pm

2 stops14h 44m

Panama City Tocumen Intl

Fri 6/19

1:14 pm-9:54 am

1 stop19h 40m

$746

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 4/1

9:34 pm-12:40 pm

1 stop16h 06m

Panama City Tocumen Intl

Wed 4/8

1:49 pm-6:26 am

2 stops15h 37m

$760
Cheapest one-way

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/9

3:08 pm-2:15 pm

2 stops24h 07m

$181

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 5/11

8:45 pm-12:46 pm

1 stop17h 01m

$192

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Charlotte to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Panama

What is the cheapest month to book a flight from Charlotte to Panama?

Currently, August is the cheapest month in which you can book a flight from Charlotte to Panama (average of $234). Flying from Charlotte to Panama in December is currently the most expensive (average of $516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 14, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Charlotte to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,291 reviews

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,291 reviews
Delta
7.9
Good
8,291 reviews

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,423 reviews
Delta
7.9
Good
8,291 reviews

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,464 reviews
Delta
7.9
Good
8,291 reviews

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charlotte to Panama?

    If you book a flight to Panama from Charlotte, you will be flying from Douglas, which is the city’s only airport. Charlotte Douglas (CLT) is located 5.7 mi from the center of Charlotte.

  • Can I find deals for flights from Charlotte to Panama that include hotel bookings?

    Yes. In addition to deals on Charlotte to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Panama.

  • Can I find deals for business class flights from Charlotte to Panama?

    Yes. Cheapflights offers flight deals from Charlotte to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Panama?

    Currently, August is the cheapest month in which you can book a flight from Charlotte to Panama (average of $234). Flying from Charlotte to Panama in December is currently the most expensive (average of $516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Charlotte to Panama

Discover the top 3 airlines that operate flights from Charlotte to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$435Average$572FlexibilityNo cancel feeOn-time71%
DeltaCheapest$447Average$567FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$467Average$547FlexibilityNo cancel feeOn-time69%

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