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$166+ Cheap flights from Charlotte (CLT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
ago. 19 — ago. 261
mar. 8/19
mar. 8/26
1 adult, Economy
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Cheap flight deals from Charlotte to Panama

Keep the following information in mind while searching for Charlotte to Panama flight deals. Data was last updated agosto 14, 2025.

Round-trip from

$385
(Mytrip)

One-way from

$166
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$551
From Charlotte Douglas to Panama
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One-way flight from Charlotte Douglas to Panama
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Highest demand for flights based on searches. 12% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Charlotte to Panama

Cheapest flights from Charlotte to Panama
Explore the most affordable flight options available from Charlotte to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 14, 2025.

This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/410:17 amCLT - PTY
2 stops11h 53mMultiple Airlines
dom. 9/73:20 amPTY - CLT
2 stops18h 39mMultiple Airlines
Deal found 8/13$385
This Avianca Connect deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2510:17 amCLT - PTY
2 stops14h 53mMultiple Airlines
dom. 9/283:20 amPTY - CLT
2 stops18h 39mMultiple Airlines
Deal found 8/14$388
This Avianca Connect deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/105:45 amCLT - PTY
2 stops20h 00mMultiple Airlines
vie. 9/123:25 amPTY - CLT
2 stops18h 34mMultiple Airlines
Deal found 8/13$389
This Avianca Connect deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/255:45 amCLT - PTY
2 stops16h 25mMultiple Airlines
sáb. 9/273:20 amPTY - CLT
2 stops18h 39mMultiple Airlines
Deal found 8/14$409
This Avianca Connect deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/17:00 amCLT - PTY
2 stops18h 45mMultiple Airlines
dom. 9/73:20 amPTY - CLT
2 stops18h 39mMultiple Airlines
Deal found 8/13$425
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/221:49 pmCLT - PTY
1 stop7h 48mMultiple Airlines
dom. 8/249:33 pmPTY - CLT
1 stop12h 29mMultiple Airlines
Deal found 8/14$452
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/271:44 pmCLT - PTY
1 stop7h 53mMultiple Airlines
jue. 10/308:25 amPTY - CLT
1 stop12h 32mMultiple Airlines
Deal found 8/13$459
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/610:42 pmCLT - PTY
1 stop9h 24mMultiple Airlines
dom. 11/912:33 pmPTY - CLT
1 stop9h 24mMultiple Airlines
Deal found 8/14$463

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
Use the filters below to find and compare flights from Charlotte to Panama that are best for you.

Fly from

Charlotte

Fly to

Panama

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 9/4

10:17 am-12:10 am

2 stops14h 53m

Panama City Tocumen Intl

lun. 9/8

10:05 pm-10:59 pm

2 stops23h 54m

$385

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 9/25

5:45 am-12:10 am

2 stops19h 25m

Panama City Tocumen Intl

dom. 9/28

3:20 am-10:59 pm

2 stops18h 39m

$388

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

lun. 10/27

6:00 am-12:40 am

2 stops19h 40m

Panama City Tocumen Intl

mié. 10/29

2:55 am-11:36 pm

2 stops19h 41m

$389

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

mié. 9/10

5:45 am-12:45 am

2 stops20h 00m

Panama City Tocumen Intl

vie. 9/12

3:25 am-10:59 pm

2 stops18h 34m

$389

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 9/25

5:45 am-9:10 pm

2 stops16h 25m

Panama City Tocumen Intl

sáb. 9/27

3:20 am-10:59 pm

2 stops18h 39m

$409

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

lun. 9/1

7:00 am-12:45 am

2 stops18h 45m

Panama City Tocumen Intl

dom. 9/7

3:20 am-10:59 pm

2 stops18h 39m

$425

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

mié. 10/8

10:17 am-9:10 pm

2 stops11h 53m

Panama City Tocumen Intl

dom. 10/12

5:25 pm-12:23 pm

2 stops17h 58m

$431

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

lun. 9/1

1:43 pm-12:45 am

2 stops12h 02m

$166

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

dom. 8/31

1:43 pm-4:30 pm

2 stops27h 47m

$169

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

mié. 11/5

9:49 am-8:50 am

2 stops23h 01m

$172

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 14 results
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Best time to book a flight from Charlotte to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Panama

What is the cheapest month to book a flight from Charlotte to Panama?

Currently, October is the cheapest month in which you can book a flight from Charlotte to Panama (average of $478). Flying from Charlotte to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to PA?

Find hourly flight availability from Charlotte to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charlotte to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated agosto 14, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charlotte to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charlotte to Panama?

    If you book a flight to Panama from Charlotte, you will be flying from Douglas, which is the city’s only airport. Charlotte Douglas (CLT) is located 5.7 mi from the center of Charlotte.

  • Can I find deals for flights from Charlotte to Panama that include hotel bookings?

    Yes. In addition to deals on Charlotte to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Panama.

  • Can I find deals for business class flights from Charlotte to Panama?

    Yes. Cheapflights offers flight deals from Charlotte to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Panama?

    Currently, October is the cheapest month in which you can book a flight from Charlotte to Panama (average of $478). Flying from Charlotte to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Charlotte to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Charlotte to Panama

Discover the top 3 airlines that operate flights from Charlotte to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$436Average$522FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$453Average$571FlexibilityNo cancel feeOn-time71%
DeltaCheapest$456Average$575FlexibilityNo cancel feeOn-timeN/A

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