Panama City

$353+ Cheap flights from Tuscany to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
FLR — PTY
Jan 1 — Jan 81
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Cheap flight deals from Tuscany to Panama City

Cheapest flights from Tuscany to Panama City
Explore the most affordable flight options available from Tuscany to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 2, 2025.

This Delta deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:00 pmFCO - PTY
2 stops32h 21mDelta
Sun 12/288:00 amPTY - FCO
1 stop17h 55mDelta
Deal found 11/30$934
This Delta deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:05 amFCO - PTY
2 stops33h 16mDelta
Sun 12/288:00 amPTY - FCO
1 stop17h 55mDelta
Deal found 11/30$1,128
This FlightHub deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:25 pmFCO - PTY
1 stop31h 20mAir Europa
Thu 12/189:30 pmPTY - FCO
1 stop30h 00mAir Europa
Deal found 11/29$1,133
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:00 amFCO - PTY
2 stops32h 55mUnited Airlines
Fri 2/2710:00 amPTY - FCO
1 stop15h 55mUnited Airlines
Deal found 12/1$1,188
This United Airlines deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:00 amFCO - PTY
2 stops32h 55mUnited Airlines
Sun 12/286:41 pmPTY - FCO
2 stops40h 29mUnited Airlines
Deal found 11/30$1,233
This KLM deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:25 pmFCO - PTY
1 stop26h 05mMultiple Airlines
Wed 12/1010:20 pmPTY - FCO
1 stop28h 35mMultiple Airlines
Deal found 12/1$1,263
This Mytrip deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:25 pmFCO - PTY
1 stop31h 20mMultiple Airlines
Wed 12/172:55 amPTY - FCO
3 stops39h 10mMultiple Airlines
Deal found 11/29$1,385
This KLM deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:25 pmFCO - PTY
1 stop26h 05mMultiple Airlines
Sun 12/143:46 pmPTY - FCO
1 stop34h 09mMultiple Airlines
Deal found 11/30$1,447
This Air Europa deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:25 pmFCO - PTY
1 stop31h 20mAir Europa
Sun 12/219:30 pmPTY - FCO
1 stop29h 55mAir Europa
Deal found 11/30$1,450
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:40 pmFCO - PTY
1 stop31h 17mDelta
Sat 1/103:20 pmPTY - FCO
2 stops22h 25mDelta
Deal found 12/2$1,478

Find flight deals from Tuscany to Panama City

Keep the following information in mind while searching for Tuscany to Panama City flight deals. Data was last updated December 2, 2025.

Round-trip from

$671
(Air Europa)

One-way from

$353
(Avianca Connect)
From Tuscany to Panama City Tocumen Intl
One-way flight from Tuscany to Panama City Tocumen Intl

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tuscany to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 2, 2025.
Use the filters below to find and compare flights from Tuscany to Panama City that are best for you.

Fly from

Tuscany

Fly to

Panama City

Route

Depart

Return

Price

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 3/12

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Mon 3/16

9:30 pm-5:25 pm

1 stop13h 55m

$739

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 4/16

9:45 am-12:55 pm

1 stop34h 10m

Panama City Tocumen Intl

Mon 4/20

2:20 pm-7:55 am

2 stops34h 35m

$802

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Tue 2/3

8:25 pm-4:30 pm

1 stop26h 05m

Panama City Tocumen Intl

Wed 2/25

10:20 pm-5:25 pm

1 stop13h 05m

$859

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Mon 3/30

7:45 pm-4:50 pm

1 stop28h 05m

Panama City Tocumen Intl

Thu 4/9

9:55 pm-7:05 pm

1 stop14h 10m

$867

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Wed 2/4

9:45 am-7:38 pm

2 stops39h 53m

Panama City Tocumen Intl

Wed 2/25

10:00 am-8:30 am

2 stops40h 30m

$897

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Tue 2/3

10:30 am-2:45 pm

2 stops34h 15m

Panama City Tocumen Intl

Wed 2/25

4:41 pm-8:30 am

2 stops33h 49m

$916

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Wed 4/1

9:45 am-4:04 am

2 stops25h 19m

Panama City Tocumen Intl

Fri 4/10

10:55 pm-8:15 am

2 stops26h 20m

$917

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Tue 3/31

10:20 am-4:04 am

2 stops24h 44m

Panama City Tocumen Intl

Tue 4/7

10:55 pm-9:15 am

2 stops27h 20m

$920

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Wed 4/1

9:45 am-4:04 am

2 stops25h 19m

Panama City Tocumen Intl

Tue 4/7

10:55 pm-9:15 am

2 stops27h 20m

$920

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Tue 2/3

8:25 pm-4:30 pm

1 stop26h 05m

Panama City Tocumen Intl

Wed 3/25

10:20 pm-10:45 pm

1 stop18h 25m

$935

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Showing 1-10 of 19 results
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Best time to book a flight from Tuscany to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Tuscany with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tuscany to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Tuscany to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from Tuscany?

    For a flight from Tuscany to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city.

  • How long is the flight from Tuscany to Panama City?

    Airlines like Air Europa and Delta fly from Tuscany to Panama City in about 15h 10m. The time it takes to get you to your destination can typically vary by up to 19h. The distance between Tuscany and Panama City is about 5881 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Tuscany to Panama City that include hotel bookings?

    Yes. In addition to deals on Tuscany to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tuscany to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tuscany to Panama City.

  • Can I find deals for business class flights from Tuscany to Panama City?

    Yes. Cheapflights offers flight deals from Tuscany to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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