To save up to 16% on this flight, we recommend booking at least 59 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Portland to Panama City from $593 1-2 weeks out and tickets from $652 for flights departing within the next 72 hours.
Our data shows that August tends to be the cheapest month to fly to Panama City from Portland. Users have commonly found prices around $546 for the month, but tickets can be as low as $294. Due to multiple factors, prepare for potentially higher prices in December.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Portland to Panama City as you normally would.