It’s generally more expensive to depart on a Thursday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charlottesville to Ottawa as you normally would.
Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Charlottesville to Ottawa.