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$611+ Cheap flights from Mississippi to OR Tambo (JNB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — JNB
Nov 19 — Nov 261
Wed 11/19
Wed 11/26
1 adult, Economy
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Cheap flight deals from Mississippi to OR Tambo

Keep the following information in mind while searching for Mississippi to OR Tambo flight deals. Data was last updated October 20, 2025.

Round-trip from

$1,236
(American Airlines)

One-way from

$611
(FlightHub)

Popular in

May

Cheapest in

March
From Mississippi to Johannesburg OR Tambo
Search Deals
One-way flight from Mississippi to Johannesburg OR Tambo
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Highest demand for flights based on searches. 23% potential increase in price ($556 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($168 potential savings vs. average RT price).
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Find flight deals from Mississippi to OR Tambo

Cheapest flights from Mississippi to OR Tambo
Explore the most affordable flight options available from Mississippi to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:44 pmMEM - JNB
2 stops34h 41mAmerican Airlines
Sat 2/2810:00 pmJNB - MEM
2 stops30h 24mAmerican Airlines
Deal found 10/20$1,262
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:10 pmBTR - JNB
2 stops29h 25mAmerican Airlines
Thu 12/117:35 pmJNB - BTR
2 stops30h 28mAmerican Airlines
Deal found 10/19$1,309
This FlightHub deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:39 pmMEM - JNB
2 stops31h 56mQatar Airways
Thu 10/238:25 pmJNB - MEM
2 stops47h 36mQatar Airways
Deal found 10/17$1,497
This IEagle deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure IEagle is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/203:42 pmMEM - JNB
2 stops34h 53mQatar Airways
Sat 10/251:55 pmJNB - MEM
2 stops38h 04mQatar Airways
Deal found 10/19$1,504
This Justfly.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:39 pmMEM - JNB
2 stops31h 01mQatar Airways
Sun 10/268:20 pmJNB - MEM
2 stops50h 59mQatar Airways
Deal found 10/20$1,534
This United deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:30 amMEM - JNB
1 stop28h 05mMultiple Airlines
Sat 2/287:45 pmJNB - MEM
2 stops34h 14mMultiple Airlines
Deal found 10/20$1,943
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:20 pmMEM - JNB
3 stops34h 20mMultiple Airlines
Sun 10/268:20 pmJNB - MEM
2 stops34h 39mMultiple Airlines
Deal found 10/20$1,949
This British Airways deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:58 pmMEM - JNB
2 stops55h 27mBritish Airways
Sun 1/1110:00 pmJNB - MEM
2 stops50h 33mBritish Airways
Deal found 10/20$1,976
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:05 pmMEM - JNB
1 stop17h 55mDelta
Sat 2/289:55 pmJNB - MEM
1 stop24h 33mDelta
Deal found 10/20$2,097
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/163:01 pmMEM - JNB
2 stops34h 29mUnited Airlines
Tue 1/137:45 pmJNB - MEM
2 stops51h 00mUnited Airlines
Deal found 10/18$2,105
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:21 pmBTR - JNB
1 stop20h 39mDelta
Thu 12/117:20 pmJNB - BTR
2 stops30h 54mDelta
Deal found 10/19$2,463

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Mississippi to Johannesburg OR Tambo Airport that are best for you.

Fly from

Mississippi

Fly to

OR Tambo

Route

Depart

Return

Price

MemphisJohannesburg

MEM - JNB

MEMJNB

Memphis

Wed 2/25

6:56 pm-10:25 am

2 stops31h 29m

Johannesburg OR Tambo

Mon 3/9

10:00 pm-11:23 pm

2 stops32h 23m

$1,237

MemphisJohannesburg

MEM - JNB

MEMJNB

Memphis

Thu 3/5

6:09 pm-7:35 am

2 stops29h 26m

Johannesburg OR Tambo

Mon 3/9

10:00 pm-7:59 pm

2 stops28h 59m

$1,237

MemphisJohannesburg

MEM - JNB

MEMJNB

Memphis

Sat 12/6

4:57 pm-10:25 am

2 stops33h 28m

Johannesburg OR Tambo

Sat 2/28

10:00 pm-8:16 pm

2 stops30h 16m

$1,262

Baton RougeJohannesburg

BTR - JNB

BTRJNB

Baton Rouge Ryan

Wed 3/25

4:45 pm-10:25 am

2 stops34h 40m

Johannesburg OR Tambo

Sun 3/29

7:25 pm-5:23 pm

2 stops28h 58m

$1,308

Baton RougeJohannesburg

BTR - JNB

BTRJNB

Baton Rouge Ryan

Thu 12/4

6:10 pm-7:35 am

2 stops29h 25m

Johannesburg OR Tambo

Thu 12/11

7:35 pm-6:03 pm

2 stops30h 28m

$1,309

MemphisJohannesburg

MEM - JNB

MEMJNB

Memphis

Sat 12/6

6:30 am-6:35 pm

1 stop28h 05m

Johannesburg OR Tambo

Sat 2/28

7:45 pm-9:59 pm

2 stops34h 14m

$1,846

ColumbusJohannesburg

GTR - JNB

GTRJNB

Columbus Golden Triangle Reg.

Thu 3/5

2:37 pm-7:00 pm

1 stop20h 23m

Johannesburg OR Tambo

Mon 3/9

11:59 pm-9:08 pm

2 stops28h 09m

$1,963

MemphisJohannesburg

MEM - JNB

MEMJNB

Memphis

Tue 12/23

6:58 pm-10:25 am

2 stops55h 27m

Johannesburg OR Tambo

Sun 1/11

10:00 pm-12:30 pm

2 stops46h 30m

$1,977

ColumbusJohannesburg

GTR - JNB

GTRJNB

Columbus Golden Triangle Reg.

Thu 3/5

2:37 pm-12:10 pm

2 stops37h 33m

Johannesburg OR Tambo

Mon 3/9

7:20 pm-9:08 pm

2 stops32h 48m

$2,001

MemphisJohannesburg

MEM - JNB

MEMJNB

Memphis

Thu 3/5

1:45 pm-7:00 pm

1 stop21h 15m

Johannesburg OR Tambo

Mon 3/9

11:59 pm-10:31 pm

2 stops29h 32m

$2,013

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 21 results
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Best time to book a flight from Mississippi to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Johannesburg OR Tambo Airport

What is the cheapest time of day to fly from MS to JNB?

Find hourly flight availability from Mississippi to OR Tambo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 34% on flights from Mississippi to Johannesburg OR Tambo Airport by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Johannesburg OR Tambo Airport?

    Airlines like American Airlines, Delta, and British Airways fly from Mississippi to Johannesburg OR Tambo Airport in about 20h 23m. The time it takes to get you to your destination can typically vary by up to 35h 04m. The distance from Mississippi to Johannesburg OR Tambo Airport is about 8666 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Mississippi to Johannesburg OR Tambo Airport?

    The most popular route from Mississippi to Johannesburg OR Tambo Airport is Memphis - Johannesburg OR Tambo. You may also consider Baton Rouge Ryan - Johannesburg OR Tambo or Columbus Golden Triangle Reg. - Johannesburg OR Tambo.

  • Can I find deals for flights from Mississippi to OR Tambo that include hotel bookings?

    Yes. In addition to deals on Mississippi to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to OR Tambo.

  • Can I find deals for business class flights from Mississippi to OR Tambo?

    Yes. Cheapflights offers flight deals from Mississippi to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

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Alternative routes for Mississippi to OR Tambo

See prices for flight routes from nearby airports that may be better suited for you.
Newark to OR Tambo flights
John F Kennedy Intl to OR Tambo flights
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Indianapolis to OR Tambo flights
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Cincinnati to OR Tambo flights

Top 3 airlines flying from Mississippi to OR Tambo

Discover the top 3 airlines that operate flights from Mississippi to OR Tambo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$1,116Average$1,459FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$1,684Average$1,781FlexibilityNo cancel feeOn-time70%
DeltaCheapest$1,800Average$2,121FlexibilityNo cancel feeOn-timeN/A

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