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OR Tambo

$813+ Cheap flights from Knoxville (TYS) to OR Tambo (JNB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JNB
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Knoxville to OR Tambo

Cheapest flights from Knoxville to OR Tambo
Explore the most affordable flight options available from Knoxville to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:29 pmTYS - JNB
2 stops32h 06mAmerican Airlines
Wed 1/1410:00 pmJNB - TYS
2 stops29h 56mAmerican Airlines
Deal found 10/27$1,456
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:01 pmTYS - JNB
3 stops32h 54mMultiple Airlines
Wed 1/147:05 pmJNB - TYS
2 stops29h 48mMultiple Airlines
Deal found 10/27$1,529
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:29 pmTYS - JNB
2 stops32h 56mAmerican Airlines
Wed 12/177:35 pmJNB - TYS
2 stops31h 06mAmerican Airlines
Deal found 10/26$1,561
This Ovago deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:00 amTYS - JNB
2 stops39h 30mLufthansa
Mon 1/127:45 pmJNB - TYS
2 stops30h 42mLufthansa
Deal found 10/27$1,573
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:29 pmTYS - JNB
2 stops32h 06mAmerican Airlines
Mon 1/1210:00 pmJNB - TYS
2 stops29h 56mAmerican Airlines
Deal found 10/28$1,606
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:45 amTYS - JNB
2 stops28h 50mUnited Airlines
Mon 1/127:45 pmJNB - TYS
2 stops30h 42mUnited Airlines
Deal found 10/26$1,612
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:15 amTYS - JNB
3 stops32h 00mMultiple Airlines
Wed 12/178:20 pmJNB - TYS
2 stops32h 36mMultiple Airlines
Deal found 10/26$1,811
This Gurufare deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amTYS - JNB
2 stops24h 20mEthiopian Air
Mon 1/122:30 pmJNB - TYS
3 stops31h 19mEthiopian Air
Deal found 10/27$1,886
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:45 amTYS - JNB
2 stops24h 20mEthiopian Air
Mon 1/122:30 pmJNB - TYS
3 stops31h 19mEthiopian Air
Deal found 10/26$1,981
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:35 amTYS - JNB
2 stops30h 30mDelta
Wed 1/149:55 pmJNB - TYS
1 stop26h 18mDelta
Deal found 10/27$2,006

Cheap flight deals from Knoxville to OR Tambo

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to OR Tambo (JNB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,236
(American Airlines)

One-way from

$813
(Etihad Airways)

Popular in

July

Cheapest in

November

Average price

$1,727
Provider with most accurate pricing for Knoxville McGhee Tyson-Johannesburg OR Tambo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Johannesburg OR Tambo flights.
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From Knoxville McGhee Tyson to Johannesburg OR Tambo
Search Deals
One-way flight from Knoxville McGhee Tyson to Johannesburg OR Tambo
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($180 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($72 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Knoxville to Johannesburg OR Tambo Airport that are best for you.

Fly from

Knoxville

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 3/12

6:50 pm-10:25 am

2 stops33h 35m

Johannesburg OR Tambo

Mon 3/16

10:00 pm-7:17 pm

2 stops27h 17m

$1,236

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 1/1

4:12 pm-7:35 am

2 stops32h 23m

Johannesburg OR Tambo

Thu 1/15

10:00 pm-9:21 pm

2 stops30h 21m

$1,436

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 12/31

12:01 pm-3:55 am

3 stops32h 54m

Johannesburg OR Tambo

Wed 1/14

7:05 pm-5:53 pm

2 stops29h 48m

$1,529

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 12/10

6:29 pm-10:25 am

2 stops32h 56m

Johannesburg OR Tambo

Wed 12/17

7:35 pm-7:41 pm

2 stops31h 06m

$1,561

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 12/31

11:00 am-9:30 am

2 stops39h 30m

Johannesburg OR Tambo

Mon 1/12

7:45 pm-7:27 pm

2 stops30h 42m

$1,573

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 12/31

4:29 pm-7:35 am

2 stops32h 06m

Johannesburg OR Tambo

Mon 1/12

10:00 pm-8:56 pm

2 stops29h 56m

$1,606

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sun 12/28

6:45 am-6:35 pm

2 stops28h 50m

Johannesburg OR Tambo

Mon 1/12

7:45 pm-7:27 pm

2 stops30h 42m

$1,612

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 1/1

11:11 am-7:00 pm

1 stop24h 49m

Johannesburg OR Tambo

Fri 1/16

11:59 pm-8:47 pm

2 stops27h 48m

$1,763

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 1/1

11:11 am-7:00 pm

1 stop24h 49m

Johannesburg OR Tambo

Thu 1/15

11:59 pm-10:17 am

2 stops41h 18m

$1,768

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 4/7

5:17 am-8:20 am

2 stops45h 03m

$813

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 12 results
1
2

Compare providers for flights from Knoxville to OR Tambo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to OR Tambo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
OvagoPrice Accuracy2 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Johannesburg OR Tambo Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Johannesburg OR Tambo Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Johannesburg OR Tambo Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Johannesburg OR Tambo Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Johannesburg OR Tambo Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Johannesburg OR Tambo Airport

What is the cheapest time of day to fly from TYS to JNB?

Find hourly flight availability from Knoxville to OR Tambo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

One of the essential ways to save on airfare from Knoxville to Johannesburg OR Tambo Airport is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 43% on airfare.

Reviews of airlines servicing OR Tambo

Get insights into the airlines that provide service to OR Tambo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to OR Tambo. Reviews last updated October 28, 2025.
Read through reviews of airlines operating flights from Knoxville to Johannesburg OR Tambo Airport, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Johannesburg OR Tambo?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Johannesburg OR Tambo from Knoxville. Booking flights from McGhee Tyson (TYS) to Johannesburg OR Tambo should be relatively easy as there are 0 daily outbound flights to Johannesburg OR Tambo from 1 airline.

  • How long is the flight from Knoxville to Johannesburg OR Tambo Airport?

    A quick flight from Knoxville to Johannesburg OR Tambo Airport can take about 33h 35m. American Airlines provides one of the quickest options available for as low as $1,236. The distance from Knoxville to Johannesburg OR Tambo Airport is about 8438 mi.

  • What is the cheapest airline to fly from Knoxville to Johannesburg OR Tambo Airport round-trip?

    Cheapflights users have booked flights from Knoxville to Johannesburg OR Tambo Airport round-trip from $1,477. This flight start at 9% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to OR Tambo that include hotel bookings?

    Yes. In addition to deals on Knoxville to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to OR Tambo.

  • Can I find deals for business class flights from Knoxville to OR Tambo?

    Yes. Cheapflights offers flight deals from Knoxville to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

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Alternative routes for Knoxville to OR Tambo

See prices for flight routes from nearby airports that may be better suited for you.
Memphis to OR Tambo flights
Nashville to OR Tambo flights
Blountville to OR Tambo flights

Top airline flying from Knoxville to OR Tambo

Discover the top airline that operate flights from Knoxville to OR Tambo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$1,477Average$2,075FlexibilityNo cancel feeOn-timeN/A

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