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OR Tambo

$681+ Cheap flights from Knoxville (TYS) to OR Tambo (JNB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JNB
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
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Cheap flight deals from Knoxville to OR Tambo

Cheapest flights from Knoxville to OR Tambo
Explore the most affordable flight options available from Knoxville to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This Qatar Airways deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/44:02 pm
TYS
-
JNB
2 stops28h 53m
Qatar Airways
Sun 3/88:30 pm
JNB
-
TYS
2 stops30h 54m
Qatar Airways
Deal found 2/16$1,505
This FlightHub deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/204:02 pm
TYS
-
JNB
2 stops28h 53m
Qatar Airways
Sun 2/221:45 pm
JNB
-
TYS
2 stops37h 55m
Qatar Airways
Deal found 2/16$1,959
This Gurufare deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:45 am
TYS
-
JNB
2 stops25h 20m
Ethiopian Air
Sat 5/2310:50 pm
JNB
-
TYS
3 stops44h 29m
Ethiopian Air
Deal found 2/14$2,119
This KAYAK deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:39 pm
TYS
-
JNB
2 stops32h 51m
Lufthansa
Thu 1/147:45 pm
JNB
-
TYS
2 stops30h 32m
Lufthansa
Deal found 2/15$2,145
This Priceline deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:50 am
TYS
-
JNB
2 stops25h 15m
Multiple Airlines
Sat 5/237:25 pm
JNB
-
TYS
2 stops28h 52m
Multiple Airlines
Deal found 2/14$2,365
This Priceline deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/204:02 pm
TYS
-
JNB
2 stops32h 33m
Multiple Airlines
Sun 2/2211:00 pm
JNB
-
TYS
3 stops47h 15m
Multiple Airlines
Deal found 2/16$2,749
This Priceline deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:20 pm
TYS
-
JNB
3 stops30h 35m
Multiple Airlines
Thu 1/147:45 pm
JNB
-
TYS
2 stops30h 32m
Multiple Airlines
Deal found 2/15$3,154
This BusinessClass deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:38 pm
TYS
-
JNB
2 stops32h 47m
British Airways
Sat 4/49:15 pm
JNB
-
TYS
2 stops29h 50m
British Airways
Deal found 2/17$3,273
This BusinessClass deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2211:57 am
TYS
-
JNB
1 stop25h 43m
Kenya Airways
Sat 5/2311:15 pm
JNB
-
TYS
2 stops27h 13m
Kenya Airways
Deal found 2/14$3,363
This BusinessClass deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/202:38 pm
TYS
-
JNB
1 stop21h 22m
SAUDIA
Sun 2/229:55 pm
JNB
-
TYS
1 stop20h 13m
SAUDIA
Deal found 2/16$3,491

Find flight deals from Knoxville to OR Tambo

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to OR Tambo (JNB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$1,505
(Qatar Airways)

One-way from

$681
(FlightHub)
Provider with most accurate pricing for Knoxville McGhee Tyson-Johannesburg OR Tambo flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Johannesburg OR Tambo flights.
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From Knoxville McGhee Tyson to Johannesburg OR Tambo
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One-way flight from Knoxville McGhee Tyson to Johannesburg OR Tambo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Knoxville to Johannesburg OR Tambo Airport that are best for you.

Fly from

Knoxville

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 3/4

4:02 pm-3:55 am

2 stops28h 53m

Johannesburg OR Tambo

Sun 3/8

12:45 pm-9:24 pm

2 stops38h 39m

$1,505

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 5/22

5:45 am-1:05 pm

2 stops25h 20m

Johannesburg OR Tambo

Sat 5/23

10:50 pm-1:19 pm

3 stops44h 29m

$2,119

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 5/22

5:50 am-1:05 pm

2 stops25h 15m

Johannesburg OR Tambo

Sat 5/23

7:25 pm-6:17 pm

2 stops28h 52m

$2,365

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 3/28

5:00 pm-9:25 am

2 stops34h 25m

Johannesburg OR Tambo

Sat 4/4

9:15 pm-9:05 pm

2 stops29h 50m

$3,273

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 5/22

11:57 am-7:40 pm

1 stop25h 43m

Johannesburg OR Tambo

Sat 5/23

11:15 pm-8:28 pm

2 stops27h 13m

$3,363

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 3/28

10:04 am-7:40 pm

1 stop27h 36m

Johannesburg OR Tambo

Sat 4/4

6:00 pm-9:51 pm

2 stops33h 51m

$4,712

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 4/28

1:20 pm-8:50 am

2 stops37h 30m

$681

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 4/7

1:20 pm-4:00 am

2 stops56h 40m

$683

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 4/28

2:25 pm-9:20 am

3 stops36h 55m

$1,593

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 4/28

3:01 pm-7:40 pm

1 stop22h 39m

$1,613

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/15

Showing 1-10 of 12 results
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Compare providers for flights from Knoxville to OR Tambo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to OR Tambo in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Johannesburg OR Tambo Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Johannesburg OR Tambo Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Johannesburg OR Tambo Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Johannesburg OR Tambo Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Johannesburg OR Tambo Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Johannesburg OR Tambo?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Johannesburg OR Tambo from Knoxville. Booking flights from McGhee Tyson (TYS) to Johannesburg OR Tambo should be relatively easy as there are 0 daily outbound flights to Johannesburg OR Tambo from 0 different airlines.

  • How long is the flight from Knoxville to Johannesburg OR Tambo Airport?

    A quick flight from Knoxville to Johannesburg OR Tambo Airport can take about 25h 20m. Qatar Airways provides one of the quickest options available for as low as $2,119. The distance from Knoxville to Johannesburg OR Tambo Airport is about 8438 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to OR Tambo that include hotel bookings?

    Yes. In addition to deals on Knoxville to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to OR Tambo.

  • Can I find deals for business class flights from Knoxville to OR Tambo?

    Yes. Cheapflights offers flight deals from Knoxville to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

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