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OR Tambo

$1,257+ Cheap flights from Knoxville (TYS) to OR Tambo (JNB)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JNB
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Knoxville to OR Tambo

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to OR Tambo (JNB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$1,257
(American Airlines)
From Knoxville McGhee Tyson to Johannesburg OR Tambo
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Find flight deals from Knoxville to OR Tambo

Cheapest flights from Knoxville to OR Tambo
Explore the most affordable flight options available from Knoxville to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Justfly.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:10 amTYS - JNB
2 stops45h 25mQatar Airways
Sat 10/41:55 pmJNB - TYS
2 stops39h 55mQatar Airways
Deal found 9/15$1,894
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/218:36 pmTYS - JNB
2 stops30h 49mMultiple Airlines
Sat 10/410:50 pmJNB - TYS
3 stops45h 55mMultiple Airlines
Deal found 9/15$2,642
This Virgin Atlantic deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/214:13 pmTYS - JNB
1 stop21h 27mVirgin Atlantic
Sat 10/49:55 pmJNB - TYS
1 stop28h 07mVirgin Atlantic
Deal found 9/15$3,101
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/226:10 amTYS - JNB
2 stops45h 25mQatar Airways
Sat 10/41:55 pmJNB - TYS
2 stops33h 48mQatar Airways
Deal found 9/15$9,199
This Virgin Atlantic deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/224:25 pmTYS - JNB
1 stop21h 15mVirgin Atlantic
Sat 10/49:55 pmJNB - TYS
1 stop26h 31mVirgin Atlantic
Deal found 9/15$12,046
This Virgin Atlantic deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2212:01 pmTYS - JNB
2 stops28h 24mMultiple Airlines
Sat 10/49:55 pmJNB - TYS
1 stop29h 31mMultiple Airlines
Deal found 9/15$12,973
This Air Canada deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/229:55 amTYS - JNB
3 stops40h 40mAir Canada
Sat 10/47:35 pmJNB - TYS
3 stops44h 54mAir Canada
Deal found 9/15$19,185

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Knoxville to Johannesburg OR Tambo Airport that are best for you.

Fly from

Knoxville

Fly to

OR Tambo

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 3/12

8:31 pm-7:35 am

2 stops29h 04m

Johannesburg OR Tambo

Mon 3/16

10:00 pm-8:39 pm

2 stops28h 39m

$1,257

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 2/16

7:01 am-8:40 am

2 stops42h 39m

Johannesburg OR Tambo

Fri 2/20

1:45 pm-5:35 pm

2 stops34h 50m

$1,340

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 3/12

5:50 am-1:05 pm

2 stops25h 15m

Johannesburg OR Tambo

Mon 3/16

2:30 pm-2:42 pm

3 stops30h 12m

$1,545

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Thu 3/12

12:00 pm-7:00 pm

1 stop25h 00m

Johannesburg OR Tambo

Mon 3/16

11:59 pm-9:43 pm

2 stops27h 44m

$1,943

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Mon 2/16

7:01 am-8:40 am

2 stops42h 39m

Johannesburg OR Tambo

Fri 2/20

2:30 pm-3:15 pm

3 stops31h 45m

$2,091

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Knoxville to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Johannesburg OR Tambo Airport

What is the cheapest time of day to fly from TYS to JNB?

Find hourly flight availability from Knoxville to OR Tambo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

One of the essential ways to save on airfare from Knoxville to Johannesburg OR Tambo Airport is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 44% on airfare.

Reviews of airlines servicing OR Tambo

Get insights into the airlines that provide service to OR Tambo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to OR Tambo. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Knoxville to Johannesburg OR Tambo Airport, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Johannesburg OR Tambo?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Johannesburg OR Tambo from Knoxville. Booking flights from McGhee Tyson (TYS) to Johannesburg OR Tambo should be relatively easy as there are 0 daily outbound flights to Johannesburg OR Tambo from 1 airline.

  • How long is the flight from Knoxville to Johannesburg OR Tambo Airport?

    A quick flight from Knoxville to Johannesburg OR Tambo Airport can take about 25h 15m. American Airlines provides one of the quickest options available for as low as $1,545. The distance from Knoxville to Johannesburg OR Tambo Airport is about 8438 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Knoxville to Johannesburg OR Tambo Airport round-trip?

    Cheapflights users have booked flights from Knoxville to Johannesburg OR Tambo Airport round-trip from $1,477.

  • Can I find deals for flights from Knoxville to OR Tambo that include hotel bookings?

    Yes. In addition to deals on Knoxville to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to OR Tambo.

  • Can I find deals for business class flights from Knoxville to OR Tambo?

    Yes. Cheapflights offers flight deals from Knoxville to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Johannesburg OR Tambo Airport?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Johannesburg OR Tambo Airport (average of $1,173). Flying from Knoxville to Johannesburg OR Tambo Airport in July is currently the most expensive (average of $1,674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

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Alternative routes for Knoxville to OR Tambo

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to OR Tambo flights
Memphis to OR Tambo flights
Blountville to OR Tambo flights

Top airline flying from Knoxville to OR Tambo

Discover the top airline that operate flights from Knoxville to OR Tambo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$1,477Average$2,075FlexibilityNo cancel feeOn-timeN/A

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