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OR Tambo

$1,255+ Cheap flights from Des Moines (DSM) to OR Tambo (JNB)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to OR Tambo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to OR Tambo (JNB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$1,255
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$1,883
From Des Moines to Johannesburg OR Tambo
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Highest demand for flights based on searches. 13% potential increase in price ($275 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($75 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to OR Tambo

Cheapest flights from Des Moines to OR Tambo
Explore the most affordable flight options available from Des Moines to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/261:48 pmDSM - JNB
2 stops34h 47mAmerican Airlines
Sun 11/210:00 pmJNB - DSM
2 stops32h 59mAmerican Airlines
Deal found 9/11$1,298
This SmartFares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmDSM - JNB
1 stop18h 45mVirgin Atlantic
Sat 11/110:00 pmJNB - DSM
2 stops31h 03mVirgin Atlantic
Deal found 9/10$1,365
This lastminute.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmDSM - JNB
1 stop18h 45mMultiple Airlines
Sat 11/111:59 pmJNB - DSM
2 stops48h 53mMultiple Airlines
Deal found 9/10$1,387
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmDSM - JNB
1 stop18h 45mDelta
Sat 11/110:00 pmJNB - DSM
2 stops31h 03mDelta
Deal found 9/10$1,424
This lastminute.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmDSM - JNB
2 stops45h 50mKLM
Sat 11/111:59 pmJNB - DSM
2 stops48h 53mKLM
Deal found 9/10$1,425
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:07 pmDSM - JNB
2 stops33h 18mAmerican Airlines
Sat 11/110:00 pmJNB - DSM
2 stops32h 54mAmerican Airlines
Deal found 9/10$1,477
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/241:00 pmDSM - JNB
2 stops21h 45mUnited Airlines
Fri 10/317:45 pmJNB - DSM
2 stops32h 47mUnited Airlines
Deal found 9/8$1,480
This Virgin Atlantic deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/242:13 pmDSM - JNB
1 stop22h 27mMultiple Airlines
Fri 10/3110:25 amJNB - DSM
2 stops43h 05mMultiple Airlines
Deal found 9/8$1,524
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:12 pmDSM - JNB
2 stops29h 48mAmerican Airlines
Fri 10/3110:00 pmJNB - DSM
2 stops30h 13mAmerican Airlines
Deal found 9/8$1,560

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Johannesburg OR Tambo Airport that are best for you.

Fly from

Des Moines

Fly to

OR Tambo

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/5

3:30 pm-7:35 am

2 stops32h 05m

Johannesburg OR Tambo

Mon 3/9

10:00 pm-10:32 pm

2 stops31h 32m

$1,255

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 10/26

1:48 pm-7:35 am

2 stops34h 47m

Johannesburg OR Tambo

Sun 11/2

10:00 pm-10:59 pm

2 stops32h 59m

$1,298

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 10/25

5:15 pm-7:00 pm

1 stop18h 45m

Johannesburg OR Tambo

Sat 11/1

10:00 pm-10:03 pm

2 stops31h 03m

$1,365

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 10/25

5:15 pm-7:00 pm

1 stop18h 45m

Johannesburg OR Tambo

Sat 11/1

11:59 pm-5:52 pm

2 stops48h 53m

$1,387

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 10/25

5:15 pm-7:00 pm

1 stop18h 45m

Johannesburg OR Tambo

Sat 11/1

10:00 pm-10:03 pm

2 stops31h 03m

$1,424

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 10/25

6:07 pm-10:25 am

2 stops33h 18m

Johannesburg OR Tambo

Sat 11/1

10:00 pm-11:54 pm

2 stops32h 54m

$1,477

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 10/24

10:50 am-7:40 pm

1 stop25h 50m

Johannesburg OR Tambo

Fri 10/31

10:25 am-10:30 pm

2 stops43h 05m

$1,524

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 2/17

4:27 pm-10:25 am

2 stops33h 58m

$3,526

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 2/17

11:04 am-7:00 pm

1 stop23h 56m

$4,363

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 2/17

11:30 am-9:30 am

3 stops38h 00m

$4,445

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 11 results
1
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Best time to book a flight from Des Moines to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Johannesburg OR Tambo Airport

What is the cheapest month to book a flight from Des Moines to Johannesburg OR Tambo Airport?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Johannesburg OR Tambo Airport (average of $1,173). Flying from Des Moines to Johannesburg OR Tambo Airport in July is currently the most expensive (average of $1,675). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to JNB?

Find hourly flight availability from Des Moines to OR Tambo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s optimal to fly from Des Moines to Johannesburg OR Tambo Airport in the afternoon. By choosing this option you can save up to 22% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing OR Tambo

Get insights into the airlines that provide service to OR Tambo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to OR Tambo. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta and United Airlines from Des Moines to Johannesburg OR Tambo Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Johannesburg OR Tambo?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Johannesburg OR Tambo. 2 airlines have flights from Des Moines to Johannesburg OR Tambo on a regular basis. Booking flights from Des Moines to Johannesburg OR Tambo should not be difficult; the airport handles an average of 0 outbound flights to Johannesburg OR Tambo per day.

  • How long is the flight from Des Moines to Johannesburg OR Tambo Airport?

    For as low as $1,365, American Airlines can have you in Johannesburg OR Tambo Airport from Des Moines in 18h 45m. Airlines will cover a distance of 8998 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Johannesburg OR Tambo Airport round-trip?

    Cheapflights users have booked flights from Des Moines to Johannesburg OR Tambo Airport round-trip from $1,322. Another airline that can offer you cheap pricing is Delta. You may be able to fly from Des Moines to Johannesburg OR Tambo Airport for 24% less than the average price by searching for these airlines.

  • Can I find deals for flights from Des Moines to OR Tambo that include hotel bookings?

    Yes. In addition to deals on Des Moines to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to OR Tambo.

  • Can I find deals for business class flights from Des Moines to OR Tambo?

    Yes. Cheapflights offers flight deals from Des Moines to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Johannesburg OR Tambo Airport?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Johannesburg OR Tambo Airport (average of $1,173). Flying from Des Moines to Johannesburg OR Tambo Airport in July is currently the most expensive (average of $1,675). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Des Moines to OR Tambo

See prices for flight routes from nearby airports that may be better suited for you.
Moline to OR Tambo flights
Omaha to OR Tambo flights

Top 2 airlines flying from Des Moines to OR Tambo

Discover the top 2 airlines that operate flights from Des Moines to OR Tambo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$1,322Average$1,503FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,410Average$1,973FlexibilityNo cancel feeOn-timeN/A

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