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OR Tambo

$875+ Cheap flights from Des Moines (DSM) to OR Tambo (JNB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Des Moines to OR Tambo

Cheapest flights from Des Moines to OR Tambo
Explore the most affordable flight options available from Des Moines to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:44 pm
DSM
-
JNB
2 stops31h 41m
Multiple Airlines
Mon 3/167:35 pm
JNB
-
DSM
2 stops29h 03m
Multiple Airlines
Deal found 1/24$1,254
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:37 pm
DSM
-
JNB
2 stops34h 58m
American Airlines
Tue 3/1710:00 pm
JNB
-
DSM
2 stops32h 40m
American Airlines
Deal found 1/26$1,256
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/111:52 pm
DSM
-
JNB
2 stops34h 43m
American Airlines
Wed 3/187:35 pm
JNB
-
DSM
2 stops30h 22m
American Airlines
Deal found 1/24$1,282
This Gotogate deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:08 pm
DSM
-
JNB
2 stops31h 32m
Qatar Airways
Tue 3/3112:40 pm
JNB
-
DSM
2 stops33h 16m
Qatar Airways
Deal found 1/24$1,299
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:58 pm
DSM
-
JNB
2 stops28h 02m
American Airlines
Sun 7/129:15 pm
JNB
-
DSM
2 stops29h 13m
American Airlines
Deal found 1/25$1,340
This FlightHub deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:27 pm
DSM
-
JNB
2 stops60h 53m
Qatar Airways
Sun 4/1212:40 pm
JNB
-
DSM
2 stops42h 31m
Qatar Airways
Deal found 1/26$1,380
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:44 pm
DSM
-
JNB
2 stops28h 51m
Multiple Airlines
Wed 3/187:35 pm
JNB
-
DSM
2 stops30h 22m
Multiple Airlines
Deal found 1/25$1,498
This Delta deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:33 am
DSM
-
JNB
1 stop24h 27m
Delta
Mon 3/167:20 pm
JNB
-
DSM
2 stops28h 34m
Delta
Deal found 1/24$1,536
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:20 pm
DSM
-
JNB
1 stop18h 40m
Delta
Tue 3/1710:00 pm
JNB
-
DSM
2 stops30h 10m
Delta
Deal found 1/26$1,547

Find flight deals from Des Moines to OR Tambo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to OR Tambo (JNB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$1,254
(American Airlines)

One-way from

$875
(American Airlines)

Popular in

June

Cheapest in

November

Average price

$1,752
Provider with most accurate pricing for Des Moines-Johannesburg OR Tambo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Johannesburg OR Tambo flights.
Search Deals
From Des Moines to Johannesburg OR Tambo
Search Deals
One-way flight from Des Moines to Johannesburg OR Tambo
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($166 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg OR Tambo Airport that are best for you.

Fly from

Des Moines

Fly to

OR Tambo

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 3/9

7:44 pm-10:25 am

2 stops31h 41m

Johannesburg OR Tambo

Mon 3/16

7:35 pm-5:38 pm

2 stops29h 03m

$1,254

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 3/10

1:37 pm-7:35 am

2 stops34h 58m

Johannesburg OR Tambo

Tue 3/17

10:00 pm-11:40 pm

2 stops32h 40m

$1,256

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 3/24

6:08 pm-8:40 am

2 stops31h 32m

Johannesburg OR Tambo

Tue 3/31

12:40 pm-2:56 pm

2 stops33h 16m

$1,299

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 6/21

7:58 pm-7:00 am

2 stops28h 02m

Johannesburg OR Tambo

Sun 7/12

9:15 pm-7:28 pm

2 stops29h 13m

$1,340

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 4/5

7:27 pm-3:20 pm

2 stops60h 53m

Johannesburg OR Tambo

Sun 4/12

12:40 pm-12:11 am

2 stops42h 31m

$1,380

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 3/9

11:33 am-7:00 pm

1 stop24h 27m

Johannesburg OR Tambo

Mon 3/16

7:20 pm-4:54 pm

2 stops28h 34m

$1,536

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 3/10

5:20 pm-7:00 pm

1 stop18h 40m

Johannesburg OR Tambo

Tue 3/17

10:00 pm-9:10 pm

2 stops30h 10m

$1,547

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/19

7:27 pm-3:35 pm

2 stops37h 08m

Johannesburg OR Tambo

Fri 3/27

12:45 pm-6:57 pm

2 stops37h 12m

$1,547

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 3/24

11:33 am-7:00 pm

1 stop24h 27m

Johannesburg OR Tambo

Tue 3/31

11:15 pm-9:10 pm

2 stops28h 55m

$1,585

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/11

1:52 pm-7:35 am

2 stops34h 43m

$875

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 16 results
1
2

Compare providers for flights from Des Moines to OR Tambo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to OR Tambo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Johannesburg OR Tambo Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Johannesburg OR Tambo Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Johannesburg OR Tambo Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Johannesburg OR Tambo Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Johannesburg OR Tambo Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Johannesburg OR Tambo Airport

How much does it cost to fly round-trip from Des Moines to Johannesburg OR Tambo Airport?

Reviews of airlines servicing OR Tambo

Get insights into the airlines that provide service to OR Tambo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to OR Tambo. Reviews last updated January 27, 2026.
See what other customers who have flown with Delta from Des Moines to Johannesburg OR Tambo Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,118 reviews

Overall

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,118 reviews
Delta
7.9
Good
8,118 reviews

Overall

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Johannesburg OR Tambo?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Johannesburg OR Tambo. 1 airline have flights from Des Moines to Johannesburg OR Tambo on a regular basis. Booking flights from Des Moines to Johannesburg OR Tambo should not be difficult; the airport handles an average of 0 outbound flights to Johannesburg OR Tambo per day.

  • How long is the flight from Des Moines to Johannesburg OR Tambo Airport?

    For as low as $1,299, American Airlines can have you in Johannesburg OR Tambo Airport from Des Moines in 31h 32m. Airlines will cover a distance of 8998 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Des Moines to Johannesburg OR Tambo Airport round-trip?

    Cheapflights users have booked flights from Des Moines to Johannesburg OR Tambo Airport round-trip from $1,410. You may be able to fly from Des Moines to Johannesburg OR Tambo Airport for 17% less than the average price by searching for this airline.

  • Can I find deals for flights from Des Moines to OR Tambo that include hotel bookings?

    Yes. In addition to deals on Des Moines to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to OR Tambo.

  • Can I find deals for business class flights from Des Moines to OR Tambo?

    Yes. Cheapflights offers flight deals from Des Moines to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

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Alternative routes for Des Moines to OR Tambo

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to OR Tambo flights
Moline to OR Tambo flights

Top airline flying from Des Moines to OR Tambo

Discover the top airline that operate flights from Des Moines to OR Tambo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$1,410Average$1,972FlexibilityNo cancel feeOn-timeN/A

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