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Odessa

$397+ Cheap flights from Tyler (TYR) to Odessa, TX

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
TYR — MAF
mai 22 — mai 291
sex 5/22
sex 5/29
1 adult, Economy
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Cheap flight deals from Tyler to Odessa

Cheapest flights from Tyler to Odessa
Explore the most affordable flight options available from Tyler to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 22, 2026.

This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 8/155:35 pm
TYR
-
MAF
1 stop4h 59m
American Airlines
sáb 8/226:26 pm
MAF
-
TYR
1 stop4h 07m
American Airlines
Deal found 4/21$442
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 5/205:55 pm
TYR
-
MAF
1 stop4h 12m
American Airlines
qua 5/278:23 pm
MAF
-
TYR
1 stop3h 17m
American Airlines
Deal found 4/22$463
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 5/55:55 pm
TYR
-
MAF
1 stop4h 12m
American Airlines
sáb 5/96:02 am
MAF
-
TYR
1 stop4h 09m
American Airlines
Deal found 4/20$484
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 5/75:55 pm
TYR
-
MAF
1 stop6h 11m
American Airlines
seg 5/115:00 am
MAF
-
TYR
1 stop5h 11m
American Airlines
Deal found 4/22$548
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 5/195:55 pm
TYR
-
MAF
1 stop4h 12m
American Airlines
ter 5/268:23 pm
MAF
-
TYR
1 stop3h 17m
American Airlines
Deal found 4/21$607

Find flight deals from Tyler to Odessa

Keep the following information in mind while searching for Tyler to Odessa flight deals. Data was last updated abril 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$442
(American Airlines)

One-way from

$397
(American Airlines)
Provider with most accurate pricing for Tyler Pounds Field-Midland Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tyler Pounds Field-Midland Intl flights.
Search Deals
From Tyler Pounds Field to Odessa
Search Deals
One-way flight from Tyler Pounds Field to Odessa
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Tyler to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 22, 2026.
Use the filters below to find and compare flights from Tyler to Odessa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

ter 5/5

5:55 pm-10:07 pm

1 stop4h 12m

Midland Intl

sáb 5/9

6:02 am-10:11 am

1 stop4h 09m

$484

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

qui 5/7

5:55 pm-12:06 am

1 stop6h 11m

Midland Intl

seg 5/11

5:00 am-10:11 am

1 stop5h 11m

$548
Quickest round-trip

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

ter 5/19

5:55 pm-10:07 pm

1 stop4h 12m

Midland Intl

ter 5/26

8:23 pm-11:40 pm

1 stop3h 17m

$607

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

sáb 8/15

5:35 pm-9:24 pm

1 stop3h 49m

Midland Intl

sáb 8/22

9:22 am-5:05 pm

2 stops7h 43m

$991
Cheapest one-way

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

ter 5/12

5:55 pm-10:07 pm

1 stop4h 12m

$397

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

qua 5/20

5:55 pm-12:06 am

1 stop6h 11m

$397
Quickest one-way

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

sáb 5/16

6:00 am-9:42 am

1 stop3h 42m

$397

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

ter 5/5

6:00 am-11:46 pm

2 stops17h 46m

$669

TylerMidland

TYR - MAF

TYRMAF

Tyler Pounds Field

qua 5/13

10:41 am-11:46 pm

2 stops13h 05m

$669

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Sorted by cheapest first

Best time to book a flight from Tyler to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from Tyler with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tyler to Odessa
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Tyler to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Tyler to Odessa?

    If you book a flight to Odessa from Tyler, you will be flying from Pounds Field, which is the city’s only airport. Tyler Pounds Field (TYR) is located 5.9 mi from the center of Tyler. There are 0 flights from Pounds Field to Odessa per day from 0 different airlines.

  • How long is the flight from Tyler to Odessa?

    American Airlines can get you from Tyler to Odessa in just under 4h 59m. Your travel time can differ by up to . There are 398 mi between Tyler and Odessa.

  • Can I find deals for flights from Tyler to Odessa that include hotel bookings?

    Yes. In addition to deals on Tyler to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tyler to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tyler to Odessa.

  • Can I find deals for business class flights from Tyler to Odessa?

    Yes. Cheapflights offers flight deals from Tyler to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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