$382+ Cheap flights from Tyler (TYR) to Odessa, TX
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYR — MAF
Jan 22 — Jan 291
1 adult, Economy
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1. Tell us where you want to go
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Best flights from Tyler to OdessaDiscover carefully curated flight deals from Tyler to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.
Discover carefully curated flight deals from Tyler to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/56:11 pmTYR - MAF
1 stop4h 26mAmerican Airlines
Fri 1/95:00 amMAF - TYR
1 stop5h 03mAmerican Airlines
Deal found 12/21![American Airlines logo]()
$794
Find flight deals from Tyler to Odessa
Keep the following information in mind while searching for Tyler to Odessa flight deals. Data was last updated December 23, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $794 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Tyler to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Tyler to Odessa that are best for you.
Fly from
Tyler
Fly to
Odessa
Route
Depart
Return
Price
TylerMidland
TYR - MAF
TYRMAF
Tyler Pounds Field
Mon 1/5
6:11 pm-10:37 pm
1 stop4h 26m
Midland Intl
Fri 1/9
5:00 am-10:03 am
1 stop5h 03m
$794
TylerMidland
TYR - MAF
TYRMAF
Tyler Pounds Field
Mon 1/5
6:11 pm-10:37 pm
1 stop4h 26m
$382
Best time to book a flight from Tyler to Odessa
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Estimated round-trip price
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Cheapflights Insights
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