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Panama City

$641+ Cheap flights from Mexico City Federal District to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from Mexico City Federal District to Panama City

Cheapest flights from Mexico City Federal District to Panama City
Explore the most affordable flight options available from Mexico City Federal District to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:45 amMEX - ECP
1 stop8h 12mUnited Airlines
Wed 12/244:45 pmECP - MEX
1 stop7h 25mUnited Airlines
Deal found 11/16$641
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/3010:05 amMEX - ECP
1 stop11h 44mUnited Airlines
Wed 12/244:45 pmECP - MEX
1 stop7h 25mUnited Airlines
Deal found 11/16$662
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:50 amMEX - ECP
2 stops13h 56mAmerican Airlines
Tue 12/2312:40 pmECP - MEX
2 stops11h 30mAmerican Airlines
Deal found 11/16$678
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2512:25 pmMEX - ECP
1 stop9h 24mUnited Airlines
Wed 12/244:45 pmECP - MEX
1 stop7h 25mUnited Airlines
Deal found 11/16$688
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:45 pmMEX - ECP
1 stop15h 34mUnited Airlines
Wed 12/244:45 pmECP - MEX
1 stop7h 25mUnited Airlines
Deal found 11/16$709
This Delta deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/302:10 pmMEX - ECP
1 stop6h 22mDelta
Wed 12/310:00 amECP - MEX
2 stops11h 40mDelta
Deal found 11/17$735
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:45 amMEX - ECP
1 stop16h 04mUnited Airlines
Tue 12/236:15 amECP - MEX
1 stop17h 55mUnited Airlines
Deal found 11/16$756
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/3010:05 amMEX - ECP
1 stop11h 44mUnited Airlines
Sun 12/219:52 amECP - MEX
1 stop14h 18mUnited Airlines
Deal found 11/16$776
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:05 amMEX - ECP
1 stop5h 58mUnited Airlines
Thu 12/254:45 pmECP - MEX
1 stop7h 25mUnited Airlines
Deal found 11/16$782
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2810:05 amMEX - ECP
1 stop5h 58mUnited Airlines
Tue 12/236:15 amECP - MEX
1 stop10h 30mUnited Airlines
Deal found 11/16$802
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:00 amMEX - ECP
2 stops15h 37mDelta
Wed 12/246:00 amECP - MEX
1 stop9h 15mDelta
Deal found 11/16$804

Cheap flight deals from Mexico City Federal District to Panama City

Keep the following information in mind while searching for Mexico City Federal District to Panama City flight deals. Data was last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$501
(United Airlines)

Popular in

January

Cheapest in

July
Provider with most accurate pricing for Mexico City Benito Juarez-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Panama City NW Florida Beaches flights.
Search Deals
From Mexico City Federal District to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to Panama City that are best for you.

Fly from

Mexico City Federal District

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 11/30

10:05 am-9:49 pm

1 stop11h 44m

Panama City NW Florida Beaches

Wed 12/24

4:45 pm-12:10 am

1 stop7h 25m

$662

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 12/15

12:25 am-11:38 am

2 stops11h 13m

Panama City NW Florida Beaches

Tue 12/23

12:40 pm-12:10 am

2 stops11h 30m

$678

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 11/28

5:45 pm-9:19 am

1 stop15h 34m

Panama City NW Florida Beaches

Wed 12/24

4:45 pm-12:10 am

1 stop7h 25m

$709

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sat 11/29

12:25 pm-9:49 pm

1 stop9h 24m

Panama City NW Florida Beaches

Wed 12/24

4:45 pm-12:10 am

1 stop7h 25m

$709

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 11/30

2:10 pm-8:32 pm

1 stop6h 22m

Panama City NW Florida Beaches

Wed 12/3

6:00 am-8:45 pm

1 stop14h 45m

$735

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 12/1

5:45 am-4:03 pm

1 stop10h 18m

Panama City NW Florida Beaches

Thu 12/25

4:45 pm-12:10 am

1 stop7h 25m

$735

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 11/30

5:45 am-9:49 pm

1 stop16h 04m

Panama City NW Florida Beaches

Tue 12/23

6:15 am-12:10 am

1 stop17h 55m

$756

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 11/30

10:05 am-9:49 pm

1 stop11h 44m

Panama City NW Florida Beaches

Sun 12/21

9:52 am-12:10 am

1 stop14h 18m

$776

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 11/27

10:05 am-4:04 pm

1 stop5h 59m

Panama City NW Florida Beaches

Thu 12/25

4:45 pm-12:10 am

1 stop7h 25m

$782

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 11/27

10:05 am-4:04 pm

1 stop5h 59m

Panama City NW Florida Beaches

Tue 12/23

6:15 am-4:45 pm

1 stop10h 30m

$782

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 11 results
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Best time to book a flight from Mexico City Federal District to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Panama City

What is the cheapest month to book a flight from Mexico City Federal District to Panama City, Florida?

Currently, August is the cheapest month in which you can book a flight from Mexico City Federal District to Panama City, Florida (average of $377). Flying from Mexico City Federal District to Panama City, Florida in January is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mexico City Federal District?

    If you book a flight to Panama City from Mexico City Federal District, you will be flying to NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • How long is the flight from Mexico City Federal District to Panama City, Florida?

    Departing from Mexico City Federal District to Panama City, Florida will take you 11h 13m. The distance between Mexico City Federal District and Panama City, Florida is about 1121 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mexico City Federal District to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Panama City.

  • Can I find deals for business class flights from Mexico City Federal District to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to Panama City, Florida?

    Currently, August is the cheapest month in which you can book a flight from Mexico City Federal District to Panama City, Florida (average of $377). Flying from Mexico City Federal District to Panama City, Florida in January is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Mexico City Federal District to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mexico City Federal District to Panama City

Discover the top airline that operate flights from Mexico City Federal District to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

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