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Panama City

$388+ Cheap flights from Mexico City Federal District to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Mar 23 — Mar 301
Mon 3/23
Mon 3/30
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to Panama City

Cheapest flights from Mexico City Federal District to Panama City
Explore the most affordable flight options available from Mexico City Federal District to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.

This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:35 am
MEX
-
ECP
2 stops23h 03m
United Airlines
Tue 4/1410:10 am
ECP
-
MEX
1 stop8h 40m
United Airlines
Deal found 2/20$535
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:05 am
MEX
-
ECP
1 stop5h 59m
Delta
Tue 5/1911:39 am
ECP
-
MEX
1 stop10h 42m
Delta
Deal found 2/17$537
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:35 am
MEX
-
ECP
2 stops17h 11m
American Airlines
Tue 5/1911:43 am
ECP
-
MEX
2 stops11h 37m
American Airlines
Deal found 2/17$551
This Aeromexico deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:15 pm
MEX
-
ECP
1 stop6h 32m
Aeromexico
Fri 10/307:45 am
ECP
-
MEX
1 stop14h 25m
Aeromexico
Deal found 2/20$554
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:50 am
MEX
-
ECP
2 stops13h 01m
Delta
Mon 5/187:41 am
ECP
-
MEX
2 stops13h 29m
Delta
Deal found 2/17$558
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:20 pm
MEX
-
ECP
2 stops18h 23m
United Airlines
Mon 3/162:10 pm
ECP
-
MEX
2 stops24h 10m
United Airlines
Deal found 2/17$560
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:50 am
MEX
-
ECP
1 stop14h 07m
United Airlines
Mon 3/165:03 pm
ECP
-
MEX
1 stop17h 02m
United Airlines
Deal found 2/17$581

Find flight deals from Mexico City Federal District to Panama City

Keep the following information in mind while searching for Mexico City Federal District to Panama City flight deals. Data was last updated February 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$537
(Delta)

One-way from

$388
(Delta)

Popular in

December

Cheapest in

April

Average price

$511
Provider with most accurate pricing for Mexico City Benito Juarez-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Panama City NW Florida Beaches flights.
Search Deals
From Mexico City Federal District to Panama City NW Florida Beaches
Search Deals
One-way flight from Mexico City Federal District to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($127 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Mexico City Federal District to Panama City that are best for you.

Fly from

Mexico City Federal District

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Tue 4/7

4:40 pm-9:38 am

2 stops15h 58m

Panama City NW Florida Beaches

Tue 4/14

10:29 am-11:10 pm

2 stops13h 41m

$535

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 5/13

7:05 am-2:04 pm

1 stop5h 59m

Panama City NW Florida Beaches

Tue 5/19

11:39 am-9:21 pm

1 stop10h 42m

$537

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 5/13

5:35 am-11:46 pm

2 stops17h 11m

Panama City NW Florida Beaches

Tue 5/19

11:43 am-10:20 pm

2 stops11h 37m

$551

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sat 5/16

7:05 am-6:36 pm

1 stop10h 31m

Panama City NW Florida Beaches

Mon 5/18

1:50 pm-9:21 pm

1 stop8h 31m

$558

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 3/12

6:50 am-9:57 pm

1 stop14h 07m

Panama City NW Florida Beaches

Mon 3/16

5:03 pm-11:15 am

1 stop19h 12m

$560

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 3/13

6:50 am-9:57 pm

1 stop14h 07m

Panama City NW Florida Beaches

Mon 3/16

5:03 pm-9:05 am

1 stop17h 02m

$581

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 3/15

8:40 am-7:27 pm

1 stop9h 47m

$388

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 3/15

6:50 am-9:57 pm

1 stop14h 07m

$388

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 3/15

8:15 am-11:04 pm

2 stops13h 49m

$390

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 2/26

8:35 am-10:39 pm

2 stops14h 04m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Showing 1-10 of 11 results
1
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Best time to book a flight from Mexico City Federal District to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Panama City

What is the cheapest month to book a flight from Mexico City Federal District to Panama City, Florida?

Currently, March is the cheapest month in which you can book a flight from Mexico City Federal District to Panama City, Florida (average of $257). Flying from Mexico City Federal District to Panama City, Florida in December is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mexico City Federal District?

    If you book a flight to Panama City from Mexico City Federal District, you will be flying to NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • How long is the flight from Mexico City Federal District to Panama City, Florida?

    Departing from Mexico City Federal District to Panama City, Florida will take you 5h 59m. The distance between Mexico City Federal District and Panama City, Florida is about 1121 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mexico City Federal District to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Panama City.

  • Can I find deals for business class flights from Mexico City Federal District to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to Panama City, Florida?

    Currently, March is the cheapest month in which you can book a flight from Mexico City Federal District to Panama City, Florida (average of $257). Flying from Mexico City Federal District to Panama City, Florida in December is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Mexico Beach

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Alternative routes for Mexico City Federal District to Panama City

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Top airline flying from Mexico City Federal District to Panama City

Discover the top airline that operate flights from Mexico City Federal District to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

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