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Panama City

$343+ Cheap flights from Mexico City Federal District to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Oct 31 — Nov 71
Fri 10/31
Fri 11/7
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to Panama City

Keep the following information in mind while searching for Mexico City Federal District to Panama City flight deals. Data was last updated October 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$500
(Delta)

One-way from

$343
(American Airlines)

Popular in

January

Cheapest in

July

Average price

$579
Provider with most accurate pricing for Mexico City Benito Juarez-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Panama City NW Florida Beaches flights.
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From Mexico City Federal District to Panama City NW Florida Beaches
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One-way flight from Mexico City Federal District to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 11% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Mexico City Federal District to Panama City

Cheapest flights from Mexico City Federal District to Panama City
Explore the most affordable flight options available from Mexico City Federal District to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2025.

This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:00 amMEX - ECP
2 stops13h 32mDelta
Thu 11/207:02 amECP - MEX
2 stops11h 53mDelta
Deal found 9/29$500
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:25 amMEX - ECP
1 stop27h 38mUnited Airlines
Mon 11/36:30 amECP - MEX
1 stop17h 40mUnited Airlines
Deal found 10/1$502
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:25 pmMEX - ECP
1 stop27h 38mUnited Airlines
Thu 11/206:30 amECP - MEX
1 stop17h 40mUnited Airlines
Deal found 9/29$521
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:00 amMEX - ECP
1 stop7h 44mAmerican Airlines
Mon 11/35:55 pmECP - MEX
2 stops17h 25mAmerican Airlines
Deal found 9/29$535
This Aeromexico deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:55 amMEX - ECP
2 stops14h 15mAeromexico
Mon 11/36:00 amECP - MEX
2 stops13h 50mAeromexico
Deal found 10/1$581
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:25 pmMEX - ECP
1 stop20h 54mUnited Airlines
Fri 11/216:30 amECP - MEX
1 stop5h 45mUnited Airlines
Deal found 9/30$585
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:45 amMEX - ECP
2 stops16h 30mAmerican Airlines
Fri 11/217:15 amECP - MEX
2 stops16h 10mAmerican Airlines
Deal found 9/30$621

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 1, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to Panama City that are best for you.

Fly from

Mexico City Federal District

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 11/13

7:00 am-8:32 pm

2 stops13h 32m

Panama City NW Florida Beaches

Thu 11/20

7:02 am-6:55 pm

2 stops11h 53m

$500

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/30

11:25 am-4:03 pm

1 stop27h 38m

Panama City NW Florida Beaches

Mon 11/3

6:30 am-12:10 am

1 stop17h 40m

$502

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/30

11:25 am-11:10 pm

1 stop10h 45m

Panama City NW Florida Beaches

Mon 11/3

6:00 am-9:30 pm

2 stops15h 30m

$502

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 11/13

12:25 pm-4:03 pm

1 stop27h 38m

Panama City NW Florida Beaches

Thu 11/20

6:30 am-12:10 am

1 stop17h 40m

$521

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/30

10:00 am-6:44 pm

1 stop7h 44m

Panama City NW Florida Beaches

Mon 11/3

5:55 pm-11:20 am

2 stops17h 25m

$535

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 11/14

12:25 pm-9:19 am

1 stop20h 54m

Panama City NW Florida Beaches

Fri 11/21

6:30 am-12:15 pm

1 stop5h 45m

$585

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 11/14

6:45 am-11:15 pm

2 stops16h 30m

Panama City NW Florida Beaches

Fri 11/21

7:15 am-11:25 pm

2 stops16h 10m

$621

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 10/31

11:30 am-10:58 am

1 stop22h 28m

$343

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/30

12:25 am-6:34 pm

2 stops17h 09m

$1,601

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/30

Best time to book a flight from Mexico City Federal District to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Panama City

What is the cheapest month to book a flight from Mexico City Federal District to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Mexico City Federal District to Panama City, Florida (average of $346). Flying from Mexico City Federal District to Panama City, Florida in March is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mexico City Federal District?

    If you book a flight to Panama City from Mexico City Federal District, you will be flying to NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • How long is the flight from Mexico City Federal District to Panama City, Florida?

    Departing from Mexico City Federal District to Panama City, Florida will take you 10h 45m. The distance between Mexico City Federal District and Panama City, Florida is about 1121 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mexico City Federal District to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Panama City.

  • Can I find deals for business class flights from Mexico City Federal District to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Mexico City Federal District to Panama City, Florida (average of $346). Flying from Mexico City Federal District to Panama City, Florida in March is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Mexico Beach

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Top airline flying from Mexico City Federal District to Panama City

Discover the top airline that operate flights from Mexico City Federal District to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

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