In terms of precipitation, rainfall in Brussels Bruxelles-National Airport ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels Bruxelles-National Airport when rainfall is around 1.6 in.

If weather is an important factor for your trip to Brussels Bruxelles-National Airport, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What are the most popular routes from South Carolina to Brussels Bruxelles-National Airport?

The most popular route from South Carolina to Brussels Bruxelles-National Airport is Charlotte Douglas - Brussels Bruxelles-National. You may also consider Charleston - Brussels Bruxelles-National or Columbia Metropolitan - Brussels Bruxelles-National.

What is the cheapest time of day to fly from SC to BRU?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Brussels Bruxelles-National Airport as you normally would.

Can I find deals for flights from South Carolina to Bruxelles-National that include hotel bookings?

Yes. In addition to deals on South Carolina to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Bruxelles-National?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Bruxelles-National.

Can I find deals for business class flights from South Carolina to Bruxelles-National?

Yes. Cheapflights offers flight deals from South Carolina to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$226+ Flights from South Carolina to Brussels Bruxelles-National Airport

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Cheap flight deals from South Carolina to Bruxelles-National

Cheapest flights from South Carolina to Bruxelles-National
Explore the most affordable flight options available from South Carolina to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

Wed 4/2210:00 am

CHS

BRU

2 stops28h 00m

United Airlines

Tue 4/289:25 am

BRU

CHS

2 stops42h 00m

United Airlines

Deal found 1/28

$485

Wed 2/256:25 am

CAE

BRU

2 stops24h 50m

United Airlines

Wed 3/410:00 am

BRU

CAE

2 stops43h 44m

United Airlines

Deal found 1/28

$486

Wed 4/2910:00 am

CHS

BRU

1 stop15h 15m

United Airlines

Tue 5/59:25 am

BRU

CHS

2 stops33h 00m

United Airlines

Deal found 1/28

$489

Wed 5/611:05 am

CHS

BRU

1 stop14h 45m

Air Canada

Fri 5/159:25 am

BRU

CHS

2 stops40h 14m

Air Canada

Deal found 1/27

$492

Wed 2/257:47 pm

CHS

BRU

1 stop29h 28m

United Airlines

Sun 3/110:00 am

BRU

CHS

2 stops57h 52m

United Airlines

Deal found 1/28

$495

Sun 5/311:05 am

CHS

BRU

2 stops38h 05m

Air Canada

Tue 5/129:25 am

BRU

CHS

2 stops35h 28m

Air Canada

Deal found 1/28

$496

Mon 5/42:48 pm

CHS

BRU

2 stops16h 27m

United Airlines

Tue 5/1212:00 pm

BRU

CHS

1 stop17h 59m

United Airlines

Deal found 1/28

$505

Thu 3/57:47 pm

CHS

BRU

2 stops30h 03m

United Airlines

Mon 3/910:15 am

BRU

CHS

1 stop28h 00m

United Airlines

Deal found 1/29

$506

Wed 4/2912:20 pm

CHS

BRU

2 stops20h 45m

British Airways

Tue 5/53:15 pm

BRU

CHS

2 stops34h 26m

British Airways

Deal found 1/28

$510

Mon 5/411:05 am

CHS

BRU

2 stops20h 10m

Air Canada

Fri 5/89:25 am

BRU

CHS

2 stops44h 34m

Air Canada

Deal found 1/28

$534

Sat 5/26:25 am

CHS

BRU

2 stops42h 45m

Air Canada

Fri 5/89:25 am

BRU

CHS

2 stops44h 34m

Air Canada

Deal found 1/28

$537

Sun 3/156:05 pm

MYR

BRU

2 stops14h 10m

United Airlines

Sun 3/2210:15 am

BRU

MYR

1 stop11h 50m

United Airlines

Deal found 1/28

$545

Best flights from South Carolina to Bruxelles-National
Discover carefully curated flight deals from South Carolina to Bruxelles-National that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 29, 2026.

Wed 2/256:25 am

CAE

BRU

2 stops24h 50m

United Airlines

Wed 3/410:00 am

BRU

CAE

2 stops43h 44m

United Airlines

Deal found 1/28

$486

Sun 5/37:44 pm

CHS

BRU

1 stop29h 56m

Delta

Tue 5/129:45 am

BRU

CHS

1 stop17h 34m

Delta

Deal found 1/28

$509

Wed 5/66:48 pm

CHS

BRU

2 stops15h 27m

Lufthansa

Mon 5/114:25 pm

BRU

CHS

2 stops37h 34m

Lufthansa

Deal found 1/28

$551

Mon 5/189:20 am

CLT

BRU

2 stops21h 55m

Air Canada

Wed 5/279:25 am

BRU

CLT

2 stops34h 48m

Air Canada

Deal found 1/28

$584

Tue 3/33:31 pm

HHH

BRU

2 stops16h 04m

American Airlines

Thu 5/283:50 pm

BRU

HHH

2 stops31h 19m

American Airlines

Deal found 1/27

$688

Sun 3/156:37 pm

MYR

BRU

3 stops32h 13m

Multiple Airlines

Sun 3/225:30 pm

BRU

MYR

2 stops32h 18m

Multiple Airlines

Deal found 1/28

$844

Wed 4/226:00 am

CHS

BRU

1 stop19h 15m

United Airlines

Tue 4/289:25 am

BRU

CHS

2 stops42h 00m

United Airlines

Deal found 1/28

$489

Wed 4/2910:00 am

CHS

BRU

1 stop15h 15m

United Airlines

Tue 5/59:25 am

BRU

CHS

2 stops33h 00m

United Airlines

Deal found 1/28

$489

Wed 2/257:47 pm

CHS

BRU

1 stop29h 28m

United Airlines

Sun 3/110:00 am

BRU

CHS

2 stops57h 52m

United Airlines

Deal found 1/28

$495

Wed 5/66:48 pm

CHS

BRU

2 stops19h 12m

United Airlines

Fri 5/1510:15 am

BRU

CHS

1 stop13h 47m

United Airlines

Deal found 1/28

$505

Tue 5/52:48 pm

CHS

BRU

2 stops16h 27m

United Airlines

Tue 5/1211:10 am

BRU

CHS

1 stop13h 31m

United Airlines

Deal found 1/28

$505

Thu 3/57:47 pm

CHS

BRU

2 stops30h 03m

United Airlines

Mon 3/911:55 am

BRU

CHS

2 stops16h 35m

United Airlines

Deal found 1/29

$506

Wed 2/181:00 pm

MYR

BRU

3 stops18h 15m

Air Canada

Wed 2/252:25 pm

BRU

MYR

3 stops27h 54m

Air Canada

Deal found 1/28

$825

Fri 3/1310:01 am

MYR

BRU

2 stops16h 49m

Multiple Airlines

Fri 3/2010:00 am

BRU

MYR

2 stops33h 32m

Multiple Airlines

Deal found 1/27

$912

Sun 3/156:05 pm

MYR

BRU

2 stops14h 10m

United Airlines

Sun 3/2210:15 am

BRU

MYR

1 stop11h 50m

United Airlines

Deal found 1/28

$545

Wed 5/1310:10 am

CLT

BRU

1 stop15h 05m

United Airlines

Tue 5/199:40 am

BRU

CLT

1 stop11h 17m

United Airlines

Deal found 1/28

$572

Fri 3/139:00 am

CAE

BRU

1 stop18h 05m

Lufthansa

Fri 3/2011:55 am

BRU

CAE

1 stop12h 06m

Lufthansa

Deal found 1/27

$1,127

Tue 3/106:20 pm

CLT

BRU

2 stops13h 55m

United Airlines

Wed 3/1810:00 am

BRU

CLT

2 stops42h 57m

United Airlines

Deal found 1/26

$580

Mon 4/132:46 pm

CLT

BRU

2 stops16h 29m

United Airlines

Thu 4/239:40 am

BRU

CLT

1 stop12h 40m

United Airlines

Deal found 1/27

$598

Tue 4/144:55 pm

CLT

BRU

2 stops14h 20m

United Airlines

Thu 4/239:40 am

BRU

CLT

2 stops17h 17m

United Airlines

Deal found 1/27

$602

Wed 4/154:55 pm

CLT

BRU

2 stops14h 20m

United Airlines

Thu 4/239:40 am

BRU

CLT

2 stops17h 17m

United Airlines

Deal found 1/27

$602

Mon 5/186:00 am

CLT

BRU

1 stop19h 15m

United Airlines

Wed 5/279:35 am

BRU

CLT

1 stop13h 10m

United Airlines

Deal found 1/27

$603

Fri 3/136:05 pm

MYR

BRU

2 stops14h 10m

United Airlines

Fri 3/2010:15 am

BRU

MYR

1 stop11h 50m

United Airlines

Deal found 1/27

$654

Wed 2/181:00 pm

MYR

BRU

2 stops18h 15m

United Airlines

Wed 2/256:45 am

BRU

MYR

2 stops16h 04m

United Airlines

Deal found 1/27

$710

Thu 2/129:00 am

CAE

BRU

2 stops16h 15m

United Airlines

Mon 2/164:55 pm

BRU

CAE

2 stops32h 03m

United Airlines

Deal found 1/27

$767

Fri 3/137:39 pm

CAE

BRU

2 stops31h 16m

United Airlines

Fri 3/202:25 pm

BRU

CAE

2 stops33h 36m

United Airlines

Deal found 1/27

$793

Last-minute flights from South Carolina to Bruxelles-National
Discover last-minute flight deals from South Carolina to Bruxelles-National. Data last updated January 29, 2026 and is based on user searches.

Fri 2/62:49 pm

CAE

BRU

2 stops16h 26m

United Airlines

Tue 2/1010:00 am

BRU

CAE

2 stops34h 14m

United Airlines

Deal found 1/26

$730

Tue 2/172:48 pm

CHS

BRU

2 stops36h 07m

United Airlines

Tue 2/2410:00 am

BRU

CHS

2 stops34h 49m

United Airlines

Deal found 1/27

$681

Wed 2/1810:32 am

CLT

BRU

2 stops21h 58m

Scandinavian Airlines

Wed 2/2510:20 am

BRU

CLT

2 stops18h 10m

Scandinavian Airlines

Deal found 1/28

$633

Wed 2/1810:32 am

CLT

BRU

2 stops26h 03m

Scandinavian Airlines

Tue 2/2410:20 am

BRU

CLT

2 stops18h 10m

Scandinavian Airlines

Deal found 1/27

$655

Wed 2/182:48 pm

CLT

BRU

2 stops13h 22m

Lufthansa

Tue 2/249:35 am

BRU

CLT

1 stop13h 20m

Lufthansa

Deal found 1/27

$683

Wed 2/182:55 pm

CLT

BRU

2 stops16h 20m

United Airlines

Wed 2/2511:55 am

BRU

CLT

1 stop13h 00m

United Airlines

Deal found 1/28

$703

Wed 2/181:00 pm

MYR

BRU

2 stops18h 15m

United Airlines

Wed 2/256:45 am

BRU

MYR

2 stops16h 04m

United Airlines

Deal found 1/27

$710

Thu 2/196:50 pm

CLT

BRU

1 stop12h 20m

Lufthansa

Tue 2/249:35 am

BRU

CLT

1 stop13h 20m

Lufthansa

Deal found 1/27

$731

Wed 2/256:25 am

CAE

BRU

2 stops24h 50m

United Airlines

Wed 3/410:00 am

BRU

CAE

2 stops43h 44m

United Airlines

Deal found 1/28

$486

Wed 2/257:47 pm

CHS

BRU

1 stop29h 28m

United Airlines

Sun 3/110:00 am

BRU

CHS

2 stops57h 52m

United Airlines

Deal found 1/28

$495

Wed 2/252:48 pm

CLT

BRU

2 stops16h 27m

United Airlines

Sun 3/111:55 am

BRU

CLT

1 stop13h 00m

United Airlines

Deal found 1/26

$650

Wed 2/255:05 pm

CLT

BRU

2 stops14h 10m

Air Canada

Sun 3/110:00 am

BRU

CLT

2 stops36h 17m

Air Canada

Deal found 1/28

$656

One-way flights from South Carolina to Bruxelles-National
Search for one-way flight options from South Carolina to Bruxelles-National. Find affordable one-way fares based on user searches. Data last updated January 29, 2026.

Tue 5/127:54 pm

CLT

BRU

2 stops37h 11m

British Airways

Deal found 1/28

$226

Tue 5/125:50 pm

CLT

BRU

1 stop15h 25m

American Airlines

Deal found 1/28

$229

Tue 5/127:18 pm

CLT

BRU

3 stops35h 57m

Multiple Airlines

Deal found 1/28

$292

Mon 4/611:10 am

CHS

BRU

2 stops38h 00m

Air Canada

Deal found 1/27

$396

Thu 6/2511:45 pm

CLT

BRU

1 stop14h 55m

American Airlines

Deal found 1/27

$420

Mon 4/67:40 pm

CHS

BRU

1 stop29h 35m

United Airlines

Deal found 1/27

$432

Mon 4/65:02 pm

CHS

BRU

3 stops58h 33m

Multiple Airlines

Deal found 1/27

$433

Thu 5/76:31 pm

MYR

BRU

2 stops15h 39m

British Airways

Deal found 1/28

$3,048

Thu 5/73:14 pm

MYR

BRU

1 stop11h 46m

United Airlines

Deal found 1/27

$3,297

Thu 5/711:57 am

MYR

BRU

3 stops19h 18m

Air Canada

Deal found 1/27

$3,319

Thu 6/253:02 pm

CLT

BRU

3 stops46h 13m

Multiple Airlines

Deal found 1/27

$7,641

Find flight deals from South Carolina to Bruxelles-National

Round-trip from	$485 (United Airlines)
One-way from	$226 (oojo)

From South Carolina to Brussels Bruxelles-National

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One-way flight from South Carolina to Brussels Bruxelles-National

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Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Wed 2/25

6:25 am-1:15 pm

2 stops24h 50m

Brussels Bruxelles-National

Wed 3/4

10:00 am-11:44 pm

2 stops43h 44m

$486

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 4/22

6:00 am-7:15 am

1 stop19h 15m

Brussels Bruxelles-National

Tue 4/28

9:25 am-9:25 pm

2 stops42h 00m

$489

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 4/29

10:00 am-7:15 am

1 stop15h 15m

Brussels Bruxelles-National

Tue 5/5

9:25 am-12:25 pm

2 stops33h 00m

$489

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 2/25

7:47 pm-7:15 am

1 stop29h 28m

Brussels Bruxelles-National

Sun 3/1

10:00 am-1:52 pm

2 stops57h 52m

$495

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 5/6

6:48 pm-8:00 pm

2 stops19h 12m

Brussels Bruxelles-National

Fri 5/15

10:15 am-6:02 pm

1 stop13h 47m

$505

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 5/5

2:48 pm-1:15 pm

2 stops16h 27m

Brussels Bruxelles-National

Tue 5/12

11:10 am-6:41 pm

1 stop13h 31m

$505

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Thu 3/5

7:47 pm-7:50 am

2 stops30h 03m

Brussels Bruxelles-National

Mon 3/9

11:55 am-11:30 pm

2 stops16h 35m

$506

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Sun 5/3

7:44 pm-7:40 am

1 stop29h 56m

Brussels Bruxelles-National

Tue 5/12

9:45 am-9:19 pm

1 stop17h 34m

$509

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Sun 3/15

6:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

Sun 3/22

10:15 am-5:05 pm

1 stop11h 50m

$545

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 5/6

6:48 pm-4:15 pm

2 stops15h 27m

Brussels Bruxelles-National

Mon 5/11

4:25 pm-11:59 pm

2 stops37h 34m

$551

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 37 results

Best time to book a flight from South Carolina to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels Bruxelles-National Airport

No data available for this route at this time. Please check back soon.

Related info for your journey

How long is the flight from South Carolina to Brussels Bruxelles-National Airport?
A quick flight from South Carolina to Brussels Bruxelles-National Airport can take about 16h 04m. United Airlines provides one of the quickest options available for as low as $688. South Carolina and Brussels Bruxelles-National Airport are separated by a distance of 4329 mi. This flight may include one or multiple stops.
What are the most popular routes from South Carolina to Brussels Bruxelles-National Airport?
The most popular route from South Carolina to Brussels Bruxelles-National Airport is Charlotte Douglas - Brussels Bruxelles-National. You may also consider Charleston - Brussels Bruxelles-National or Columbia Metropolitan - Brussels Bruxelles-National.
Can I find deals for flights from South Carolina to Bruxelles-National that include hotel bookings?
Yes. In addition to deals on South Carolina to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Bruxelles-National?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Bruxelles-National.
Can I find deals for business class flights from South Carolina to Bruxelles-National?
Yes. Cheapflights offers flight deals from South Carolina to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Mechelen

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Top airline flying from South Carolina to Bruxelles-National

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$591	Average$1,057	FlexibilityNo cancel fee	On-time69%

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$226+ Cheap flights from South Carolina to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from South Carolina to Bruxelles-National

Cheapest flights from South Carolina to Bruxelles-NationalExplore the most affordable flight options available from South Carolina to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

Explore the most affordable flight options available from South Carolina to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

Find flight deals from South Carolina to Bruxelles-National

Keep the following information in mind while searching for South Carolina to Bruxelles-National flight deals. Data was last updated January 29, 2026.

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Best time to book a flight from South Carolina to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels Bruxelles-National Airport

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from South Carolina to Brussels Bruxelles-National Airport?

What are the most popular routes from South Carolina to Brussels Bruxelles-National Airport?

Can I find deals for flights from South Carolina to Bruxelles-National that include hotel bookings?

How can I find direct flights from South Carolina to Bruxelles-National?

Can I find deals for business class flights from South Carolina to Bruxelles-National?

Traveling to a place near Brussels Bruxelles-National Airport?

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Alternative routes for South Carolina to Bruxelles-National

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Top airline flying from South Carolina to Bruxelles-National

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Cheapest flights from South Carolina to Bruxelles-National
Explore the most affordable flight options available from South Carolina to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.