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Bruxelles-National

$276+ Cheap flights from South Carolina to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BRU
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from South Carolina to Bruxelles-National

Keep the following information in mind while searching for South Carolina to Bruxelles-National flight deals. Data was last updated September 15, 2025.

Round-trip from

$510
(FlightHub)

One-way from

$276
(Kiwi.com)
From South Carolina to Brussels Bruxelles-National
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One-way flight from South Carolina to Brussels Bruxelles-National
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Find flight deals from South Carolina to Bruxelles-National

Cheapest flights from South Carolina to Bruxelles-National
Explore the most affordable flight options available from South Carolina to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/141:15 pmCLT - BRU
2 stops23h 05mScandinavian Airlines
Tue 10/217:10 pmBRU - CLT
2 stops34h 40mScandinavian Airlines
Deal found 9/14$510
This lol.travel deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2610:00 amCLT - BRU
1 stop16h 15mUnited Airlines
Tue 11/1111:55 amBRU - CLT
1 stop12h 56mUnited Airlines
Deal found 9/12$519
This Gotogate deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/193:15 pmCLT - BRU
1 stop10h 35mAir Canada
Tue 11/410:00 amBRU - CLT
2 stops16h 57mAir Canada
Deal found 9/14$524
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:02 amCLT - BRU
2 stops17h 38mScandinavian Airlines
Sun 11/238:30 pmBRU - CLT
2 stops31h 27mScandinavian Airlines
Deal found 9/11$526
This lastminute.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:00 amCLT - BRU
2 stops21h 40mScandinavian Airlines
Tue 11/410:20 amBRU - CLT
2 stops17h 27mScandinavian Airlines
Deal found 9/14$529
This Flighttix deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1910:34 amCLT - BRU
1 stop14h 41mUnited Airlines
Tue 11/411:55 amBRU - CLT
1 stop12h 56mUnited Airlines
Deal found 9/12$531
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:00 amCLT - BRU
2 stops18h 50mUnited Airlines
Tue 12/210:00 amBRU - CLT
2 stops33h 14mUnited Airlines
Deal found 9/14$534
This Flighttix deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/192:51 pmCLT - BRU
1 stop10h 24mBrussels Airlines
Tue 11/411:55 amBRU - CLT
1 stop12h 56mBrussels Airlines
Deal found 9/14$537
This lol.travel deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/265:15 pmCLT - BRU
2 stops33h 35mAir Canada
Tue 11/1110:00 amBRU - CLT
2 stops16h 57mAir Canada
Deal found 9/12$540
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amCLT - BRU
2 stops20h 50mAir Canada
Wed 11/510:00 amBRU - CLT
2 stops19h 58mAir Canada
Deal found 9/14$547
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:20 amCAE - BRU
1 stop16h 35mUnited Airlines
Tue 11/410:00 amBRU - CAE
2 stops41h 30mUnited Airlines
Deal found 9/13$554
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/282:29 pmCAE - BRU
1 stop12h 26mUnited Airlines
Fri 12/510:00 amBRU - CAE
2 stops33h 47mUnited Airlines
Deal found 9/12$603

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Fly from

South Carolina

Fly to

Bruxelles-National

Route

Depart

Return

Price

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 10/14

1:15 pm-6:20 pm

2 stops23h 05m

Brussels Bruxelles-National

Tue 10/21

7:10 pm-11:50 pm

2 stops34h 40m

$510

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 10/26

10:00 am-7:15 am

1 stop16h 15m

Brussels Bruxelles-National

Tue 11/11

11:55 am-6:51 pm

1 stop12h 56m

$519

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 11/19

10:02 am-9:40 am

2 stops17h 38m

Brussels Bruxelles-National

Sun 11/23

8:30 pm-9:57 pm

2 stops31h 27m

$526

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 11/19

7:00 am-7:50 am

2 stops18h 50m

Brussels Bruxelles-National

Tue 12/2

10:00 am-1:14 pm

2 stops33h 14m

$534

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 10/19

6:00 am-9:40 am

2 stops21h 40m

Brussels Bruxelles-National

Tue 11/4

10:20 am-9:47 pm

2 stops17h 27m

$539

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Fri 10/24

6:00 am-9:40 am

2 stops21h 40m

Brussels Bruxelles-National

Thu 10/30

10:20 am-9:47 pm

2 stops16h 27m

$548

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 11/19

6:40 am-8:55 am

1 stop20h 15m

Brussels Bruxelles-National

Tue 12/2

10:00 am-8:57 pm

2 stops16h 57m

$553

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 10/29

10:02 am-2:30 pm

3 stops23h 28m

Brussels Bruxelles-National

Sun 11/9

10:20 am-9:26 pm

2 stops17h 06m

$553

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Tue 10/28

10:20 am-7:55 am

1 stop16h 35m

Brussels Bruxelles-National

Tue 11/4

10:00 am-9:30 pm

2 stops41h 30m

$554

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 11/19

1:22 pm-9:00 am

1 stop13h 38m

Brussels Bruxelles-National

Tue 12/2

11:00 am-10:46 pm

1 stop17h 46m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 28 results
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Best time to book a flight from South Carolina to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels Bruxelles-National Airport

What is the cheapest time of day to fly from SC to BRU?

Find hourly flight availability from South Carolina to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Brussels Bruxelles-National Airport as you normally would.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Brussels Bruxelles-National Airport?

    A quick flight from South Carolina to Brussels Bruxelles-National Airport can take about 16h 15m. Scandinavian Airlines provides one of the quickest options available for as low as $519. South Carolina and Brussels Bruxelles-National Airport are separated by a distance of 4194 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Brussels Bruxelles-National Airport?

    The most popular route from South Carolina to Brussels Bruxelles-National Airport is Charlotte Douglas - Brussels Bruxelles-National. You may also consider Charleston - Brussels Bruxelles-National or Columbia Metropolitan - Brussels Bruxelles-National.

  • Can I find deals for flights from South Carolina to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on South Carolina to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Bruxelles-National.

  • Can I find deals for business class flights from South Carolina to Bruxelles-National?

    Yes. Cheapflights offers flight deals from South Carolina to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Brussels Bruxelles-National Airport?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Brussels Bruxelles-National Airport (average of $614). Flying from South Carolina to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Charleroi
Mons
Mechelen
Zaventem

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Bruxelles-National

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Bruxelles-National flights
John F Kennedy Intl to Bruxelles-National flights
Dulles Intl to Bruxelles-National flights
O'Hare Intl to Bruxelles-National flights
LaGuardia to Bruxelles-National flights
Reagan-National to Bruxelles-National flights
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Boston to Bruxelles-National flights
Dallas/Fort Worth to Bruxelles-National flights
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Midway to Bruxelles-National flights
John F Kennedy Intl to Charleroi Brussels flights
Hobby to Bruxelles-National flights
Charlotte to Bruxelles-National flights
Newark to Charleroi Brussels flights
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Ontario to Bruxelles-National flights
George Bush Intcntl to Bruxelles-National flights
Sky Harbor Intl to Bruxelles-National flights
Boston to Charleroi Brussels flights
Portland to Bruxelles-National flights
Dulles Intl to Charleroi Brussels flights
Love Field to Bruxelles-National flights
St. Louis to Bruxelles-National flights
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Minneapolis to Bruxelles-National flights
Jacksonville to Bruxelles-National flights
O'Hare Intl to Charleroi Brussels flights
Los Angeles to Charleroi Brussels flights
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Miami to Charleroi Brussels flights
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Top airline flying from South Carolina to Bruxelles-National

Discover the top airline that operate flights from South Carolina to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$551Average$998FlexibilityNo cancel feeOn-time69%

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