HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Brussels

$271+ Cheap flights from South Carolina to Brussels

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BRU
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Brussels with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Brussels

Keep the following information in mind while searching for South Carolina to Brussels flight deals. Data was last updated julio 3, 2025.

Round-trip from

$564
(lastminute.com)

One-way from

$271
(Kiwi.com)
From South Carolina to Brussels
Search Deals
One-way flight from South Carolina to Brussels
Search Deals

Find flight deals from South Carolina to Brussels

Cheapest flights from South Carolina to Brussels
Explore the most affordable flight options available from South Carolina to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This lastminute.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/38:30 amCLT - BRU
2 stops17h 30mAir Canada
mar. 8/1910:00 amBRU - CLT
2 stops17h 21mAir Canada
Deal found 7/2$564
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/36:45 amCLT - BRU
2 stops19h 15mUnited Airlines
mar. 8/1910:00 amBRU - CLT
2 stops34h 09mUnited Airlines
Deal found 7/3$583
This lastminute.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/31:07 pmCLT - BRU
1 stop13h 23mVirgin Atlantic
mar. 8/1910:45 amBRU - CLT
1 stop14h 08mVirgin Atlantic
Deal found 7/2$589
This KLM deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/31:07 pmCLT - BRU
1 stop13h 23mMultiple Airlines
mar. 8/1910:45 amBRU - CLT
1 stop17h 47mMultiple Airlines
Deal found 7/1$598
This Justfly.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/2310:04 amCLT - BRU
2 stops18h 11mScandinavian Airlines
mié. 10/2910:20 amBRU - CLT
2 stops18h 34mScandinavian Airlines
Deal found 7/3$614
This Netflights deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Netflights is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/157:00 amCHS - BRU
1 stop19h 40mVirgin Atlantic
vie. 8/2210:45 amBRU - CHS
1 stop14h 09mVirgin Atlantic
Deal found 7/1$622
This CheapTickets.ch deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapTickets.ch is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/1710:53 amMYR - BRU
2 stops15h 07mLufthansa
dom. 8/2410:00 amBRU - MYR
2 stops31h 51mLufthansa
Deal found 7/3$629
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/174:55 pmCHS - BRU
1 stop32h 55mUnited Airlines
dom. 8/2410:00 amBRU - CHS
2 stops34h 28mUnited Airlines
Deal found 7/3$635
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/177:45 pmCAE - BRU
1 stop29h 40mUnited Airlines
dom. 8/2410:00 amBRU - CAE
2 stops41h 44mUnited Airlines
Deal found 7/2$638
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/176:00 amMYR - BRU
2 stops20h 40mDelta
dom. 8/2410:45 amBRU - MYR
1 stop19h 04mDelta
Deal found 7/3$660
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2911:50 pmCLT - BRU
1 stop11h 50mAmerican Airlines
dom. 11/911:20 amBRU - CLT
1 stop13h 45mAmerican Airlines
Deal found 7/1$662
This Booking.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/297:30 pmCLT - BRU
1 stop19h 05mBritish Airways
dom. 11/911:20 amBRU - CLT
1 stop13h 45mBritish Airways
Deal found 7/2$664

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from South Carolina to Brussels that are best for you.

Fly from

South Carolina

Fly to

Brussels

Route

Depart

Return

Price

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

dom. 8/3

8:30 am-8:00 am

2 stops17h 30m

Brussels Bruxelles-National

mar. 8/19

10:00 am-9:21 pm

2 stops17h 21m

$564

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

dom. 8/3

6:45 am-8:00 am

2 stops19h 15m

Brussels Bruxelles-National

mar. 8/19

10:00 am-2:09 pm

2 stops34h 09m

$583

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

dom. 8/3

1:07 pm-8:30 am

1 stop13h 23m

Brussels Bruxelles-National

mar. 8/19

10:45 am-6:53 pm

1 stop14h 08m

$589

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

dom. 8/3

1:07 pm-8:30 am

1 stop13h 23m

Brussels Bruxelles-National

mar. 8/19

10:45 am-10:32 pm

1 stop17h 47m

$598

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

mar. 9/23

10:04 am-10:15 am

2 stops18h 11m

Brussels Bruxelles-National

mié. 10/29

10:20 am-11:54 pm

2 stops18h 34m

$614

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

vie. 8/15

7:00 am-8:40 am

1 stop19h 40m

Brussels Bruxelles-National

vie. 8/22

10:45 am-6:54 pm

1 stop14h 09m

$622

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

dom. 8/17

10:53 am-8:00 am

2 stops15h 07m

Brussels Bruxelles-National

dom. 8/24

10:00 am-11:51 am

2 stops31h 51m

$629

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

dom. 8/17

4:55 pm-7:50 am

1 stop32h 55m

Brussels Bruxelles-National

dom. 8/24

10:00 am-2:28 pm

2 stops34h 28m

$635

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

dom. 8/17

7:45 pm-7:25 am

1 stop29h 40m

Brussels Bruxelles-National

dom. 8/24

10:00 am-9:44 pm

2 stops41h 44m

$638

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

dom. 8/17

6:00 am-8:40 am

2 stops20h 40m

Brussels Bruxelles-National

dom. 8/24

10:45 am-11:49 pm

1 stop19h 04m

$660

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 36 results
1
2
3
4

Best time to book a flight from South Carolina to Brussels

Have a flexible travel schedule? Discover the best time to fly to Brussels from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Brussels

What is the cheapest time of day to fly from SC to BRU?

Find hourly flight availability from South Carolina to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Brussels as you normally would.

Reviews of airlines servicing Brussels

Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated julio 3, 2025.
Read reviews from past customers who have flown Delta, KLM, and Austrian Airlines from South Carolina to Brussels. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,367 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Austrian Airlines
7.6
Good
809 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Virgin Atlantic
7.4
Good
654 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Brussels one-way?

    To fly one-way, consider booking your trip with Brussels Airlines, which is currently one of the cheapest options available, starting at $435. United Airlines flights start at $438 while deals on Iberia start at $447 one-way.

  • What are the most popular routes from South Carolina to Brussels?

    While some choose either Charleston - Brussels Bruxelles-National or Columbia Metropolitan - Brussels Bruxelles-National, Charlotte Douglas - Brussels Bruxelles-National is the most popular route from South Carolina to Brussels.

  • Can I find deals for flights from South Carolina to Brussels that include hotel bookings?

    Yes. In addition to deals on South Carolina to Brussels flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Brussels?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Brussels.

  • Can I find deals for business class flights from South Carolina to Brussels?

    Yes. Cheapflights offers flight deals from South Carolina to Brussels by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Brussels?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Brussels (average of $614). Flying from South Carolina to Brussels in June is currently the most expensive (average of $1,079). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Brussels

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Bruxelles-National flights
Newark to Bruxelles-National flights
Dulles Intl to Bruxelles-National flights
Dallas/Fort Worth to Bruxelles-National flights
O'Hare Intl to Bruxelles-National flights
LaGuardia to Bruxelles-National flights
Boston to Bruxelles-National flights
Love Field to Bruxelles-National flights
Baltimore to Bruxelles-National flights
Seattle to Bruxelles-National flights
Reagan-National to Bruxelles-National flights
Los Angeles to Bruxelles-National flights
Atlanta to Bruxelles-National flights
John F Kennedy Intl to Charleroi Brussels flights
Midway to Bruxelles-National flights
Miami to Bruxelles-National flights
Austin to Bruxelles-National flights
Minneapolis to Bruxelles-National flights
San Francisco to Bruxelles-National flights
Newark to Charleroi Brussels flights
Charlotte to Bruxelles-National flights
Philadelphia to Bruxelles-National flights
Richmond to Bruxelles-National flights
Norfolk to Bruxelles-National flights
Denver to Bruxelles-National flights
Hobby to Bruxelles-National flights
Dulles Intl to Charleroi Brussels flights
Fort Lauderdale to Bruxelles-National flights
Boston to Charleroi Brussels flights
O'Hare Intl to Charleroi Brussels flights
Las Vegas to Bruxelles-National flights
Seattle to Charleroi Brussels flights
George Bush Intcntl to Bruxelles-National flights
San Diego to Bruxelles-National flights
Ontario to Bruxelles-National flights
Raleigh to Bruxelles-National flights
Santa Ana to Bruxelles-National flights
Sky Harbor Intl to Bruxelles-National flights
Tampa to Bruxelles-National flights
Orlando to Bruxelles-National flights
Portland to Bruxelles-National flights
Des Moines to Bruxelles-National flights
Dallas/Fort Worth to Charleroi Brussels flights
Detroit to Bruxelles-National flights
Los Angeles to Charleroi Brussels flights
Pittsburgh to Bruxelles-National flights
Grand Rapids to Bruxelles-National flights
Cleveland to Bruxelles-National flights

Top airline flying from South Carolina to Brussels

Discover the top airline that operate flights from South Carolina to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$551Average$990FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.