What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?

Flying on Turkish Airlines is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at $767. Additional round-trip tickets that might be worth considering are offered by Air Europa and United Airlines, with the lowest prices starting at $1,050 and $1,057, respectively. Turkish Airlines is 10% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Panama City to Brussels Bruxelles-National Airport?

Travelers seeking maximum savings on their Panama City to Brussels Bruxelles-National Airport flight should consider departing on Monday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Brussels Bruxelles-National Airport ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels Bruxelles-National Airport when rainfall is around 1.6 in.

If weather is an important factor for your trip to Brussels Bruxelles-National Airport, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What is the cheapest month to fly from Panama City to Brussels Bruxelles-National Airport?

Our data shows that January tends to be the cheapest month to fly to Brussels Bruxelles-National Airport from Panama City. Users have commonly found prices around $861 for the month, but tickets can be as low as $667. Due to multiple factors, prepare for potentially higher prices in July.

What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

If you book a flight to Brussels Bruxelles-National from Panama City, you will be flying from Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Tocumen Intl to Brussels Bruxelles-National per day from 2 different airlines.

Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Bruxelles-National?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.

Can I find deals for business class flights from Panama City to Bruxelles-National?

Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$516+ Flights from Panama City to Brussels Bruxelles-National Airport

Q: What is the cheapest day to fly round-trip from Panama City to Brussels Bruxelles-National Airport?

Travelers have found that booking a Sunday departure is the best way to save up to 27% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

Q: How far in advance should I book a flight from Panama City to Brussels Bruxelles-National Airport?

Users have found that booking a flight from Panama City to Brussels Bruxelles-National Airport at least 61 days early can save you up to 48% on average compared to booking a flight this week. If booking 61 days before your flight isn’t an option for you, users have found flights from Panama City to Brussels Bruxelles-National Airport for as little as $805 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $992 for flights departing within the next 3 days.

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Find cheap flights from Panama City to Bruxelles-National with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Brussels Bruxelles-National are usually found in January or February, booked 62 days in advance, depart on a Monday or Saturday and return on a Tuesday

Cheap flight deals from Panama City to Bruxelles-National

Round-trip from	$767 (Turkish Airlines)
One-way from	$516 (Turkish Airlines)
Popular in	July
Cheapest in	January
Average price	$957

From Panama City Tocumen Intl to Brussels Bruxelles-National

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One-way flight from Panama City Tocumen Intl to Brussels Bruxelles-National

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Highest demand for flights based on searches. 7% potential increase in price ($68 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Panama City to Bruxelles-National

Cheapest flights from Panama City to Bruxelles-National
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 18, 2025.

dom. 8/179:55 pmPTY - BRU

1 stop36h 30mTurkish Airlines

jue. 8/2111:15 amBRU - PTY

1 stop39h 45mTurkish Airlines

Deal found 7/16

$767

lun. 11/106:20 pmPTY - BRU

1 stop22h 15mIberia

mié. 2/47:00 amBRU - PTY

1 stop15h 45mIberia

Deal found 7/17

$785

lun. 11/106:20 pmPTY - BRU

1 stop14h 25mMultiple Airlines

mié. 2/47:00 amBRU - PTY

2 stops20h 00mMultiple Airlines

Deal found 7/16

$893

jue. 11/279:30 pmPTY - BRU

1 stop30h 20mAir Europa

sáb. 1/310:45 amBRU - PTY

1 stop15h 00mAir Europa

Deal found 7/15

$1,012

vie. 9/59:45 amPTY - BRU

1 stop14h 15mUnited Airlines

jue. 9/2512:00 pmBRU - PTY

2 stops32h 50mUnited Airlines

Deal found 7/16

$1,057

lun. 12/156:45 pmPTY - BRU

1 stop13h 30mKLM

sáb. 1/106:15 amBRU - PTY

1 stop16h 15mKLM

Deal found 7/17

$1,097

Best flights from Panama City to Bruxelles-National
Discover carefully curated flight deals from Panama City to Bruxelles-National that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated julio 18, 2025.

dom. 8/179:55 pmPTY - BRU

1 stop36h 30mTurkish Airlines

jue. 8/2111:15 amBRU - PTY

1 stop39h 45mTurkish Airlines

Deal found 7/16

$767

mar. 9/98:25 pmPTY - BRU

1 stop14h 15mAir Europa

lun. 9/2910:45 amBRU - PTY

1 stop14h 55mAir Europa

Deal found 7/15

$1,050

vie. 9/59:45 amPTY - BRU

1 stop14h 15mUnited Airlines

jue. 9/2512:00 pmBRU - PTY

2 stops32h 50mUnited Airlines

Deal found 7/16

$1,057

sáb. 9/65:10 pmPTY - BRU

1 stop35h 15mIberia

vie. 9/267:05 amBRU - PTY

1 stop15h 35mIberia

Deal found 7/16

$1,072

mar. 8/198:25 pmPTY - BRU

2 stops30h 50mMultiple Airlines

lun. 8/258:55 amBRU - PTY

1 stop16h 45mMultiple Airlines

Deal found 7/16

$1,086

mar. 8/196:50 pmPTY - BRU

1 stop12h 45mKLM

lun. 8/256:10 amBRU - PTY

1 stop17h 40mKLM

Deal found 7/17

$1,239

Last-minute flights from Panama City to Bruxelles-National
Discover last-minute flight deals from Panama City to Bruxelles-National. Data last updated julio 18, 2025 and is based on user searches.

sáb. 7/196:50 pmPTY - BRU

1 stop20h 25mKLM

dom. 7/2710:35 amBRU - PTY

1 stop13h 15mKLM

Deal found 7/17

$1,131

mié. 7/238:25 pmPTY - BRU

1 stop30h 20mAir Europa

lun. 7/2810:45 amBRU - PTY

1 stop14h 55mAir Europa

Deal found 7/15

$2,837

mié. 7/239:55 pmPTY - BRU

1 stop36h 55mTurkish Airlines

lun. 7/282:25 pmBRU - PTY

2 stops34h 55mTurkish Airlines

Deal found 7/15

$6,673

mié. 7/232:28 pmPTY - BRU

2 stops17h 07mDelta

lun. 7/286:10 amBRU - PTY

2 stops38h 03mDelta

Deal found 7/17

$7,912

jue. 7/245:10 pmPTY - BRU

1 stop22h 20mIberia

sáb. 8/212:10 pmBRU - PTY

2 stops55h 44mIberia

Deal found 7/15

$1,247

jue. 7/246:50 pmPTY - BRU

1 stop32h 00mKLM

sáb. 8/210:35 amBRU - PTY

1 stop13h 15mKLM

Deal found 7/15

$1,334

jue. 7/2411:05 amPTY - BRU

3 stops23h 45mMultiple Airlines

sáb. 8/28:40 pmBRU - PTY

3 stops31h 30mMultiple Airlines

Deal found 7/17

$1,372

jue. 7/249:45 amPTY - BRU

1 stop15h 00mUnited Airlines

sáb. 8/210:45 amBRU - PTY

1 stop33h 11mUnited Airlines

Deal found 7/17

$1,389

dom. 8/179:55 pmPTY - BRU

1 stop36h 30mTurkish Airlines

jue. 8/2111:15 amBRU - PTY

1 stop39h 45mTurkish Airlines

Deal found 7/16

$767

mar. 8/198:25 pmPTY - BRU

1 stop14h 15mAir Europa

lun. 8/2510:45 amBRU - PTY

1 stop14h 55mAir Europa

Deal found 7/16

$1,064

mar. 8/198:25 pmPTY - BRU

2 stops30h 50mMultiple Airlines

lun. 8/258:55 amBRU - PTY

1 stop16h 45mMultiple Airlines

Deal found 7/16

$1,086

vie. 8/299:45 amPTY - BRU

1 stop15h 00mUnited Airlines

vie. 11/2111:55 amBRU - PTY

2 stops32h 00mUnited Airlines

Deal found 7/14

$1,057

One-way flights from Panama City to Bruxelles-National
Search for one-way flight options from Panama City to Bruxelles-National. Find affordable one-way fares based on user searches. Data last updated julio 18, 2025.

dom. 8/109:55 pmPTY - BRU

1 stop29h 15mTurkish Airlines

Deal found 7/17

$516

sáb. 8/93:20 amPTY - BRU

2 stops25h 05mMultiple Airlines

Deal found 7/17

$896

dom. 8/173:30 pmPTY - BRU

2 stops20h 25mIberia

Deal found 7/17

$939

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

dom. 8/17

9:55 pm-5:25 pm

1 stop36h 30m

Brussels Bruxelles-National

jue. 8/21

11:15 am-8:00 pm

1 stop39h 45m

$767

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

mar. 9/9

8:25 pm-5:40 pm

1 stop14h 15m

Brussels Bruxelles-National

lun. 9/29

10:45 am-6:40 pm

1 stop14h 55m

$1,050

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

vie. 9/5

3:30 pm-7:00 am

2 stops32h 30m

Brussels Bruxelles-National

vie. 9/26

12:00 pm-1:50 pm

2 stops32h 50m

$1,057

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

sáb. 9/6

5:10 pm-11:25 am

1 stop35h 15m

Brussels Bruxelles-National

vie. 9/26

7:05 am-3:40 pm

1 stop15h 35m

$1,072

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

mar. 8/19

8:25 pm-10:15 am

2 stops30h 50m

Brussels Bruxelles-National

lun. 8/25

8:55 am-6:40 pm

1 stop16h 45m

$1,086

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

mar. 8/19

6:50 pm-2:35 pm

1 stop12h 45m

Brussels Bruxelles-National

lun. 8/25

6:10 am-4:50 pm

1 stop17h 40m

$1,239

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

dom. 8/10

9:55 pm-10:10 am

1 stop29h 15m

$516

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

sáb. 8/9

3:20 am-11:25 am

2 stops25h 05m

$896

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

dom. 8/17

3:30 pm-6:55 pm

2 stops20h 25m

$939

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/15

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

The price you pay for your flight from Panama City to Brussels Bruxelles-National Airport may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Currently, November is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $614). Flying from Panama City to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,081). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to BRU?

A simple way to save on the total cost of your ticket is to fly from Panama City to Brussels Bruxelles-National Airport in the afternoon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight at noon.

How much does it cost to fly round-trip from Panama City to Brussels Bruxelles-National Airport?

Reviews of airlines servicing Bruxelles-National

Read reviews from past customers who have flown KLM, United Airlines, and Turkish Airlines from Panama City to Brussels Bruxelles-National Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

KLM

7.8

Good

1,374 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

KLM

7.8

Good

1,374 reviews

KLM

7.8

Good

1,374 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

United Airlines

7.4

Good

8,864 reviews

KLM

7.8

Good

1,374 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Turkish Airlines

7.3

Good

3,906 reviews

KLM

7.8

Good

1,374 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Air Europa

7.0

Good

540 reviews

KLM

7.8

Good

1,374 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Iberia

7.0

Good

2,841 reviews

KLM

7.8

Good

1,374 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?
If you book a flight to Brussels Bruxelles-National from Panama City, you will be flying from Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Tocumen Intl to Brussels Bruxelles-National per day from 2 different airlines.
What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?
Flying on Turkish Airlines is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at $767. Additional round-trip tickets that might be worth considering are offered by Air Europa and United Airlines, with the lowest prices starting at $1,050 and $1,057, respectively. Turkish Airlines is 10% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?
Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Bruxelles-National?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.
Can I find deals for business class flights from Panama City to Bruxelles-National?
Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?
Currently, November is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $614). Flying from Panama City to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,081). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to Bruxelles-National

Airline	Cheapest	Average	Flexibility	On-time
Air Europa	Cheapest$715	Average$857	FlexibilityNo cancel fee	On-time83%
Air France	Cheapest$785	Average$997	FlexibilityNo cancel fee	On-time77%

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$516+ Cheap flights from Panama City (PTY) to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Bruxelles-National with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Brussels Bruxelles-National are usually found in January or February, booked 62 days in advance, depart on a Monday or Saturday and return on a Tuesday

Cheap flight deals from Panama City to Bruxelles-National

Round-trip from

One-way from

Popular in

Cheapest in

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Find flight deals from Panama City to Bruxelles-National

Cheapest flights from Panama City to Bruxelles-NationalExplore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 18, 2025.

Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Bruxelles-National. Price data was last updated on July 11, 2025.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

What is the cheapest time of day to fly from PTY to BRU?

Find hourly flight availability from Panama City to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 18, 2025.

How much does it cost to fly round-trip from Panama City to Brussels Bruxelles-National Airport?

Reviews of airlines servicing Bruxelles-National

Related info for your journey

Find useful and relevant information for your journey from Panama City to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?

Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

How can I find direct flights from Panama City to Bruxelles-National?

Can I find deals for business class flights from Panama City to Bruxelles-National?

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Traveling to a place near Brussels Bruxelles-National Airport?

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Other flights to Bruxelles-National

Explore flights to Bruxelles-National departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on julio 18, 2025.

Top 2 airlines flying from Panama City to Bruxelles-National

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Cheapest flights from Panama City to Bruxelles-National
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 18, 2025.