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Missouri

$753+ Cheap flights from Santiago (SCL) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — STL
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Santiago to Missouri

Cheapest flights from Santiago to Missouri
Explore the most affordable flight options available from Santiago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:10 pmSCL - STL
1 stop22h 25mDelta
Mon 12/89:30 amSTL - SCL
1 stop19h 10mDelta
Deal found 11/12$755
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:30 pmSCL - STL
1 stop20h 03mDelta
Thu 12/1111:40 amSTL - SCL
1 stop17h 00mDelta
Deal found 11/12$758
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2410:45 pmSCL - STL
2 stops18h 39mUnited Airlines
Mon 12/81:00 pmSTL - SCL
2 stops16h 50mUnited Airlines
Deal found 11/12$760
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:45 pmSCL - STL
1 stop20h 19mUnited Airlines
Sun 12/76:42 pmSTL - SCL
2 stops35h 08mUnited Airlines
Deal found 11/11$769
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:10 pmSCL - STL
1 stop25h 48mDelta
Sun 12/76:00 amSTL - SCL
1 stop22h 40mDelta
Deal found 11/12$795
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:10 pmSCL - STL
1 stop14h 33mDelta
Fri 12/511:40 amSTL - SCL
1 stop15h 30mDelta
Deal found 11/12$798
This LATAM Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:25 amSCL - STL
2 stops29h 24mLATAM Airlines
Thu 12/116:00 amSTL - SCL
2 stops19h 30mLATAM Airlines
Deal found 11/12$800
This LATAM Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:10 pmSCL - STL
1 stop14h 35mLATAM Airlines
Sun 12/79:30 amSTL - SCL
1 stop17h 40mLATAM Airlines
Deal found 11/11$804
This LATAM Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:35 pmSCL - STL
2 stops18h 14mLATAM Airlines
Wed 12/102:02 pmSTL - SCL
3 stops21h 28mLATAM Airlines
Deal found 11/12$805
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:10 pmSCL - STL
1 stop22h 07mDelta
Sun 1/47:00 amSTL - SCL
1 stop20h 10mDelta
Deal found 11/12$835
This LATAM Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:25 amSCL - STL
2 stops29h 24mLATAM Airlines
Sun 12/75:12 pmSTL - SCL
2 stops27h 13mLATAM Airlines
Deal found 11/12$840
This LATAM Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:35 pmSCL - STL
2 stops18h 14mLATAM Airlines
Fri 12/59:30 amSTL - SCL
2 stops17h 30mLATAM Airlines
Deal found 11/12$845

Cheap flight deals from Santiago to Missouri

Keep the following information in mind while searching for Santiago to Missouri flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$753
(LATAM Airlines)

Popular in

March

Cheapest in

August

Average price

$913
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Lambert-St Louis flights.
Search Deals
From Santiago Arturo Merino Benitez to Missouri
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Santiago to Missouri that are best for you.

Fly from

Santiago

Fly to

Missouri

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 3/2

6:30 pm-9:08 am

2 stops17h 38m

Lambert-St Louis

Tue 3/10

1:00 pm-7:00 am

2 stops16h 00m

$753

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/27

11:30 pm-4:33 pm

1 stop20h 03m

Lambert-St Louis

Mon 12/8

9:30 am-5:35 am

2 stops17h 05m

$755

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 3/2

11:15 pm-11:38 pm

1 stop27h 23m

Lambert-St Louis

Tue 3/10

1:00 pm-7:00 am

1 stop16h 00m

$755

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 11/25

11:25 pm-1:00 pm

2 stops16h 35m

Lambert-St Louis

Wed 12/10

11:40 am-5:35 am

2 stops14h 55m

$758

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 11/24

11:10 pm-1:00 pm

1 stop16h 50m

Lambert-St Louis

Tue 12/9

1:59 pm-7:40 am

1 stop14h 41m

$758

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 11/26

11:10 pm-1:56 pm

1 stop17h 46m

Lambert-St Louis

Tue 12/9

1:59 pm-7:40 am

1 stop14h 41m

$758

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 11/24

11:10 pm-1:00 pm

1 stop16h 50m

Lambert-St Louis

Mon 12/8

7:05 am-5:35 am

2 stops19h 30m

$758

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/27

11:10 pm-6:35 pm

1 stop22h 25m

Lambert-St Louis

Wed 12/10

11:40 am-6:10 am

1 stop15h 30m

$758

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 11/26

11:10 pm-6:35 pm

1 stop22h 25m

Lambert-St Louis

Mon 12/8

1:57 pm-7:40 am

1 stop14h 43m

$758

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 11/25

11:30 pm-4:33 pm

1 stop20h 03m

Lambert-St Louis

Thu 12/11

11:40 am-7:40 am

1 stop17h 00m

$758

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 12 results
1
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Best time to book a flight from Santiago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Missouri

What is the cheapest month to book a flight from Santiago to Missouri?

Currently, September is the cheapest month in which you can book a flight from Santiago to Missouri (average of $660). Flying from Santiago to Missouri in January is currently the most expensive (average of $941). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Santiago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santiago to Missouri?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly out of if you book a flight from Santiago to Missouri. It is only a 8.4 mi journey to Arturo Merino Benitez (SCL) from Santiago’s city center.

  • How long is the flight from Santiago to Missouri?

    Airlines like LATAM Airlines and Delta fly from Santiago to Missouri in about 17h 38m. The time it takes to get you to your destination can typically vary by up to 2h 25m. Santiago and Missouri are separated by a distance of 5137 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Santiago to Missouri that include hotel bookings?

    Yes. In addition to deals on Santiago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Missouri.

  • Can I find deals for business class flights from Santiago to Missouri?

    Yes. Cheapflights offers flight deals from Santiago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Santiago to Missouri (average of $660). Flying from Santiago to Missouri in January is currently the most expensive (average of $941). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Santiago to Missouri

Discover the top 2 airlines that operate flights from Santiago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$843Average$1,065FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$862Average$1,091FlexibilityNo cancel feeOn-time71%

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