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Missouri

$790+ Cheap flights from Santiago (SCL) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — STL
Jan 26 — Feb 21
Mon 1/26
Mon 2/2
1 adult, Economy
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Cheap flight deals from Santiago to Missouri

Best flights from Santiago to Missouri
Discover carefully curated flight deals from Santiago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 27, 2025.

This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:45 amSCL - STL
2 stops16h 53mDelta
Mon 6/157:05 pmSTL - SCL
2 stops18h 00mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:40 pmSCL - STL
1 stop15h 05mDelta
Tue 6/1611:51 amSTL - SCL
2 stops17h 09mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:40 pmSCL - STL
1 stop20h 18mDelta
Wed 6/105:30 pmSTL - SCL
1 stop12h 45mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:45 amSCL - STL
2 stops16h 53mDelta
Wed 6/1011:51 amSTL - SCL
2 stops17h 09mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:40 pmSCL - STL
1 stop15h 05mDelta
Mon 6/151:30 pmSTL - SCL
1 stop16h 45mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:45 amSCL - STL
2 stops16h 53mDelta
Thu 6/113:42 pmSTL - SCL
1 stop14h 33mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:00 pmSCL - STL
2 stops20h 02mDelta
Thu 6/115:30 pmSTL - SCL
1 stop12h 45mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:00 pmSCL - STL
2 stops17h 58mDelta
Mon 6/155:30 pmSTL - SCL
1 stop12h 45mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:00 pmSCL - STL
2 stops17h 58mDelta
Wed 6/1011:51 amSTL - SCL
2 stops17h 09mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:00 pmSCL - STL
2 stops20h 02mDelta
Wed 6/103:42 pmSTL - SCL
1 stop14h 33mDelta
Deal found 12/26$790
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:45 amSCL - STL
2 stops16h 53mDelta
Tue 6/161:30 pmSTL - SCL
2 stops15h 05mDelta
Deal found 12/26$790

Find flight deals from Santiago to Missouri

Keep the following information in mind while searching for Santiago to Missouri flight deals. Data was last updated December 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$790
(Delta)

Popular in

March

Cheapest in

August

Average price

$795
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Lambert-St Louis flights.
Search Deals
From Santiago Arturo Merino Benitez to Missouri
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($107 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
Use the filters below to find and compare flights from Santiago to Missouri that are best for you.

Fly from

Santiago

Fly to

Missouri

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 5/26

7:45 am-11:38 pm

2 stops16h 53m

Lambert-St Louis

Mon 6/15

7:05 pm-2:05 pm

2 stops18h 00m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 5/21

8:40 pm-10:45 am

1 stop15h 05m

Lambert-St Louis

Tue 6/16

11:51 am-6:00 am

2 stops17h 09m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 5/26

8:40 pm-3:58 pm

1 stop20h 18m

Lambert-St Louis

Wed 6/10

5:30 pm-7:15 am

1 stop12h 45m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 5/20

7:45 am-11:38 pm

2 stops16h 53m

Lambert-St Louis

Wed 6/10

11:51 am-6:00 am

2 stops17h 09m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 5/20

8:40 pm-10:45 am

1 stop15h 05m

Lambert-St Louis

Mon 6/15

1:30 pm-7:15 am

1 stop16h 45m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 5/26

7:45 am-11:38 pm

2 stops16h 53m

Lambert-St Louis

Thu 6/11

3:42 pm-7:15 am

1 stop14h 33m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 5/21

11:00 pm-6:02 pm

2 stops20h 02m

Lambert-St Louis

Thu 6/11

5:30 pm-7:15 am

1 stop12h 45m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 5/25

11:00 pm-3:58 pm

2 stops17h 58m

Lambert-St Louis

Mon 6/15

5:30 pm-7:15 am

1 stop12h 45m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 5/25

11:00 pm-3:58 pm

2 stops17h 58m

Lambert-St Louis

Wed 6/10

11:51 am-6:00 am

2 stops17h 09m

$790

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 5/21

11:00 pm-6:02 pm

2 stops20h 02m

Lambert-St Louis

Wed 6/10

3:42 pm-7:15 am

1 stop14h 33m

$790

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 11 results
1
2

Best time to book a flight from Santiago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Missouri

What is the cheapest month to book a flight from Santiago to Missouri?

Currently, September is the cheapest month in which you can book a flight from Santiago to Missouri (average of $660). Flying from Santiago to Missouri in January is currently the most expensive (average of $1,034). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 27, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Santiago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,018 reviews

Overall

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,018 reviews
Delta
7.9
Good
8,018 reviews

Overall

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,067 reviews
Delta
7.9
Good
8,018 reviews

Overall

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santiago to Missouri?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly out of if you book a flight from Santiago to Missouri. It is only a 8.4 mi journey to Arturo Merino Benitez (SCL) from Santiago’s city center.

  • How long is the flight from Santiago to Missouri?

    Airlines like Delta, United Airlines, and LATAM Airlines fly from Santiago to Missouri in about 13h 38m. The time it takes to get you to your destination can typically vary by up to 8h 44m. Santiago and Missouri are separated by a distance of 5137 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Santiago to Missouri that include hotel bookings?

    Yes. In addition to deals on Santiago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Missouri.

  • Can I find deals for business class flights from Santiago to Missouri?

    Yes. Cheapflights offers flight deals from Santiago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Santiago to Missouri (average of $660). Flying from Santiago to Missouri in January is currently the most expensive (average of $1,034). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Santiago to Missouri

Discover the top 2 airlines that operate flights from Santiago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$877Average$1,065FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$948Average$1,150FlexibilityNo cancel feeOn-time71%

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