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Missouri

$491+ Cheap flights from Santiago (SCL) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — STL
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Santiago to Missouri

Keep the following information in mind while searching for Santiago to Missouri flight deals. Data was last updated junio 12, 2025.

Round-trip from

$1,007
(American Airlines)

One-way from

$491
(Copa Airlines)

Popular in

August

Cheapest in

April

Average price

$1,054
From Santiago Arturo Merino Benitez to Missouri
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One-way flight from Santiago Arturo Merino Benitez to Missouri
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Highest demand for flights based on searches. 11% potential increase in price ($133 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Santiago to Missouri

Cheapest flights from Santiago to Missouri
Explore the most affordable flight options available from Santiago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/299:50 pmSCL - STL
1 stop27h 07mAmerican Airlines
mar. 8/125:22 amSTL - SCL
1 stop24h 33mAmerican Airlines
Deal found 6/11$1,007
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/84:55 pmSCL - STL
2 stops20h 39mDelta
lun. 7/145:23 pmSTL - SCL
1 stop12h 37mDelta
Deal found 6/9$1,020
This LATAM Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/2812:37 amSCL - STL
2 stops24h 16mLATAM Airlines
mar. 8/121:26 pmSTL - SCL
1 stop16h 34mLATAM Airlines
Deal found 6/11$1,073
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/2912:12 pmSCL - STL
2 stops28h 04mMultiple Airlines
mar. 8/125:26 pmSTL - SCL
3 stops33h 51mMultiple Airlines
Deal found 6/11$1,109
This eDestinos deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/1712:13 amSCL - STL
2 stops19h 15mCopa Airlines
sáb. 6/218:05 amSTL - SCL
2 stops19h 59mCopa Airlines
Deal found 6/11$1,591

Cheapflights Fare Finder

Customize your flight search to find flights from Santiago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Santiago to Missouri that are best for you.

Fly from

Santiago

Fly to

Missouri

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

mar. 7/29

9:50 pm-11:57 pm

1 stop27h 07m

Lambert-St Louis

mar. 8/12

5:22 am-6:55 am

1 stop24h 33m

$1,007

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

mar. 7/8

4:55 pm-12:34 pm

2 stops20h 39m

Lambert-St Louis

lun. 7/14

5:23 pm-7:00 am

1 stop12h 37m

$1,020

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

lun. 7/28

12:37 am-11:53 pm

2 stops24h 16m

Lambert-St Louis

mar. 8/12

11:02 am-5:40 am

2 stops17h 38m

$1,073

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

mar. 7/29

12:12 pm-3:16 pm

2 stops28h 04m

Lambert-St Louis

mar. 8/12

5:26 pm-4:17 am

3 stops33h 51m

$1,109

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

lun. 7/7

2:23 am-9:59 am

2 stops32h 36m

Lambert-St Louis

lun. 7/14

8:00 am-5:04 am

2 stops20h 04m

$1,954

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

vie. 11/21

2:42 am-9:48 am

2 stops34h 06m

$491

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

sáb. 11/22

8:50 pm-3:26 pm

1 stop21h 36m

$593

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

jue. 6/19

5:28 pm-11:53 pm

3 stops55h 25m

$645

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

jue. 6/19

8:40 pm-9:43 am

1 stop14h 03m

$671

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Santiago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Missouri

What is the cheapest month to book a flight from Santiago to Missouri?

Currently, August is the cheapest month in which you can book a flight from Santiago to Missouri (average of $311). Flying from Santiago to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated junio 12, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines and Copa Airlines from Santiago to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
9,531 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Santiago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santiago to Missouri?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly out of if you book a flight from Santiago to Missouri. It is only a 8.4 mi journey to Arturo Merino Benitez (SCL) from Santiago’s city center.

  • What are the cheapest airlines to fly from Santiago to Missouri one-way?

    For one-way options, check prices for Copa Airlines. According to our data, you can fly for as low as $491. Users have also found prices from $593 and $671 on Air Canada and LATAM Airlines, respectively.

  • Can I find deals for flights from Santiago to Missouri that include hotel bookings?

    Yes. In addition to deals on Santiago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Missouri.

  • Can I find deals for business class flights from Santiago to Missouri?

    Yes. Cheapflights offers flight deals from Santiago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Santiago to Missouri (average of $311). Flying from Santiago to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Santiago to Missouri

Discover the top 2 airlines that operate flights from Santiago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$752Average$1,005FlexibilityNo cancel feeOn-time81%
DeltaCheapest$843Average$1,159FlexibilityNo cancel feeOn-timeN/A

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