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Missouri

$261+ Cheap flights from Santiago (SCL) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — STL
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Santiago to Missouri

Cheapest flights from Santiago to Missouri
Explore the most affordable flight options available from Santiago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This LATAM Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:40 am
SCL
-
STL
2 stops19h 32m
LATAM Airlines
Wed 8/51:30 pm
STL
-
SCL
2 stops16h 25m
LATAM Airlines
Deal found 2/11$795
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:40 pm
SCL
-
STL
1 stop15h 05m
Delta
Wed 8/57:20 am
STL
-
SCL
1 stop22h 55m
Delta
Deal found 2/8$816
This LATAM Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:05 pm
SCL
-
STL
2 stops34h 02m
LATAM Airlines
Wed 7/86:00 am
STL
-
SCL
2 stops23h 00m
LATAM Airlines
Deal found 2/11$827
This Orbitz deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:00 pm
SCL
-
STL
2 stops21h 12m
LATAM Airlines
Thu 9/37:05 pm
STL
-
SCL
3 stops25h 10m
LATAM Airlines
Deal found 2/11$860
This Expedia deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:25 am
SCL
-
STL
2 stops34h 04m
Air Canada
Mon 3/94:05 pm
STL
-
SCL
1 stop17h 10m
Air Canada
Deal found 2/10$871

Find flight deals from Santiago to Missouri

Keep the following information in mind while searching for Santiago to Missouri flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$797
(LATAM Airlines)

One-way from

$261
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$953
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Lambert-St Louis flights.
Search Deals
From Santiago Arturo Merino Benitez to Missouri
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Missouri
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Santiago to Missouri that are best for you.

Fly from

Santiago

Fly to

Missouri

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 8/3

8:40 pm-10:45 am

1 stop15h 05m

Lambert-St Louis

Thu 9/3

7:20 am-7:15 am

1 stop22h 55m

$816

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 7/15

8:40 pm-10:45 am

1 stop15h 05m

Lambert-St Louis

Wed 8/5

3:42 pm-7:15 am

1 stop14h 33m

$816

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 8/3

11:00 pm-7:12 pm

2 stops21h 12m

Lambert-St Louis

Thu 9/3

7:05 pm-9:15 pm

3 stops25h 10m

$860

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 2/23

10:45 pm-9:23 am

1 stop13h 38m

Lambert-St Louis

Tue 3/10

10:05 am-7:50 am

1 stop19h 45m

$924

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 2/24

10:45 pm-9:23 am

1 stop13h 38m

Lambert-St Louis

Tue 3/10

6:25 am-7:50 am

2 stops23h 25m

$924

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Tue 2/24

10:45 pm-12:21 pm

2 stops16h 36m

Lambert-St Louis

Mon 3/9

11:25 am-7:50 am

2 stops18h 25m

$924

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 3/2

10:45 pm-2:29 pm

2 stops18h 44m

Lambert-St Louis

Wed 3/11

10:05 am-7:50 am

1 stop19h 45m

$924

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 2/23

10:30 am-6:51 am

2 stops47h 21m

$305

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 2/26

10:30 am-6:51 am

2 stops47h 21m

$311

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 2/28

10:30 am-6:51 am

2 stops47h 21m

$333

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 18 results
1
2

Best time to book a flight from Santiago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Missouri

What is the cheapest month to book a flight from Santiago to Missouri?

Currently, September is the cheapest month in which you can book a flight from Santiago to Missouri (average of $660). Flying from Santiago to Missouri in January is currently the most expensive (average of $1,031). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 12, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Santiago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,180 reviews

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,180 reviews
Delta
7.9
Good
8,180 reviews

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,271 reviews
Delta
7.9
Good
8,180 reviews

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santiago to Missouri?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly out of if you book a flight from Santiago to Missouri. It is only a 8.4 mi journey to Arturo Merino Benitez (SCL) from Santiago’s city center.

  • How long is the flight from Santiago to Missouri?

    Airlines like LATAM Airlines and Delta fly from Santiago to Missouri in about 15h 05m. The time it takes to get you to your destination can typically vary by up to 4h 27m. Santiago and Missouri are separated by a distance of 5137 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Santiago to Missouri that include hotel bookings?

    Yes. In addition to deals on Santiago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Missouri.

  • Can I find deals for business class flights from Santiago to Missouri?

    Yes. Cheapflights offers flight deals from Santiago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Santiago to Missouri (average of $660). Flying from Santiago to Missouri in January is currently the most expensive (average of $1,031). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Santiago to Missouri

Discover the top 2 airlines that operate flights from Santiago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$877Average$1,159FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$948Average$1,150FlexibilityNo cancel feeOn-time71%

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