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$389+ Cheap flights from Santiago (SCL) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — STL
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Santiago to Missouri

Keep the following information in mind while searching for Santiago to Missouri flight deals. Data was last updated July 31, 2025.

Round-trip from

$784
(LATAM Airlines)

One-way from

$389
(Kiwi.com)

Popular in

August

Cheapest in

April

Average price

$1,018
From Santiago Arturo Merino Benitez to Missouri
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One-way flight from Santiago Arturo Merino Benitez to Missouri
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Highest demand for flights based on searches. 8% potential increase in price ($95 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santiago to Missouri

Cheapest flights from Santiago to Missouri
Explore the most affordable flight options available from Santiago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This LATAM Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:15 pmSCL - STL
1 stop14h 25mLATAM Airlines
Mon 11/179:00 amSTL - SCL
2 stops18h 35mLATAM Airlines
Deal found 7/30$784
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:15 pmSCL - STL
1 stop16h 41mDelta
Mon 11/174:00 pmSTL - SCL
1 stop12h 00mDelta
Deal found 7/29$989
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/133:30 pmSCL - STL
3 stops20h 10mMultiple Airlines
Sat 9/201:00 pmSTL - SCL
3 stops39h 45mMultiple Airlines
Deal found 7/30$1,515
This Booking.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:26 amSCL - STL
2 stops32h 36mCopa Airlines
Sat 9/208:15 amSTL - SCL
2 stops43h 43mCopa Airlines
Deal found 7/30$2,136

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Santiago to Missouri that are best for you.

Fly from

Santiago

Fly to

Missouri

Route

Depart

Return

Price

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/13

11:15 pm-10:40 am

1 stop14h 25m

Lambert-St Louis

Mon 11/17

9:00 am-6:35 am

2 stops18h 35m

$784

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Thu 11/13

11:15 pm-12:56 pm

1 stop16h 41m

Lambert-St Louis

Mon 11/17

4:00 pm-7:00 am

1 stop12h 00m

$989

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Sat 9/13

3:30 pm-9:40 am

3 stops20h 10m

Lambert-St Louis

Sat 9/20

1:00 pm-6:45 am

3 stops39h 45m

$1,515

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Fri 9/12

3:26 am-10:02 am

2 stops32h 36m

Lambert-St Louis

Sat 9/20

8:15 am-5:58 am

2 stops43h 43m

$2,136

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Wed 9/17

3:33 pm-9:40 am

3 stops20h 07m

$389

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 12/1

10:35 am-11:39 pm

2 stops16h 04m

$554

SantiagoSt. Louis

SCL - STL

SCLSTL

Santiago Arturo Merino Benitez

Mon 12/1

11:15 pm-10:46 am

1 stop14h 31m

$577

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Santiago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Missouri

What is the cheapest month to book a flight from Santiago to Missouri?

Currently, August is the cheapest month in which you can book a flight from Santiago to Missouri (average of $311). Flying from Santiago to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and Copa Airlines from Santiago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
LATAM Airlines
7.5
Good
1,822 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santiago to Missouri?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly out of if you book a flight from Santiago to Missouri. It is only a 8.4 mi journey to Arturo Merino Benitez (SCL) from Santiago’s city center.

  • Can I find deals for flights from Santiago to Missouri that include hotel bookings?

    Yes. In addition to deals on Santiago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Missouri.

  • Can I find deals for business class flights from Santiago to Missouri?

    Yes. Cheapflights offers flight deals from Santiago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Santiago to Missouri (average of $311). Flying from Santiago to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Santiago to Missouri

Discover the top 2 airlines that operate flights from Santiago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$782Average$1,076FlexibilityNo cancel feeOn-time71%
DeltaCheapest$925Average$1,159FlexibilityNo cancel feeOn-timeN/A

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