$143+ Cheap flights from Portland, ME (PWM) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Apr 22 — Apr 291
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to MissouriExplore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:07 am
PWM
- STL
1 stop7h 56m
American Airlines
Wed 5/64:30 pm
STL
- PWM
1 stop5h 57m
American Airlines
Deal found 3/18![American Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:03 am
PWM
- STL
1 stop7h 19m
Delta
Tue 4/146:48 am
STL
- PWM
1 stop4h 17m
Delta
Deal found 3/18![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:01 pm
PWM
- STL
1 stop6h 45m
American Airlines
Wed 4/156:35 am
STL
- PWM
1 stop7h 34m
American Airlines
Deal found 3/19![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:50 pm
PWM
- STL
1 stop7h 35m
Southwest
Wed 4/151:45 pm
STL
- PWM
2 stops7h 50m
Southwest
Deal found 3/19![Southwest logo]()
$320
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:01 pm
PWM
- MCI
1 stop6h 58m
American Airlines
Tue 5/54:51 pm
MCI
- PWM
1 stop5h 36m
American Airlines
Deal found 3/20![American Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:50 pm
PWM
- MCI
1 stop7h 41m
United Airlines
Tue 5/53:22 pm
MCI
- PWM
2 stops7h 37m
United Airlines
Deal found 3/20![United Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
PWM
- STL
1 stop7h 48m
American Airlines
Mon 4/205:21 pm
STL
- PWM
1 stop5h 06m
American Airlines
Deal found 3/18![American Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
PWM
- SGF
1 stop6h 27m
Delta
Thu 5/283:22 pm
SGF
- PWM
1 stop6h 47m
Delta
Deal found 3/22![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:30 am
PWM
- STL
1 stop6h 20m
Southwest
Mon 5/184:00 pm
STL
- PWM
1 stop6h 25m
Southwest
Deal found 3/18![Southwest logo]()
$365
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:55 pm
PWM
- STL
1 stop6h 10m
Southwest
Wed 5/61:45 pm
STL
- PWM
2 stops7h 50m
Southwest
Deal found 3/18![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:01 pm
PWM
- STL
1 stop6h 45m
American Airlines
Thu 5/75:21 pm
STL
- PWM
1 stop5h 01m
American Airlines
Deal found 3/18![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:01 pm
PWM
- STL
1 stop6h 55m
American Airlines
Sat 5/238:02 pm
STL
- PWM
1 stop14h 44m
American Airlines
Deal found 3/20![American Airlines logo]()
$374
Best flights from Portland to MissouriDiscover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
Discover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:50 pm
PWM
- MCI
1 stop7h 41m
United Airlines
Tue 5/53:22 pm
MCI
- PWM
2 stops7h 37m
United Airlines
Deal found 3/20![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:30 am
PWM
- STL
1 stop6h 20m
Southwest
Tue 5/126:35 am
STL
- PWM
1 stop4h 45m
Southwest
Deal found 3/18![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:03 am
PWM
- STL
1 stop5h 37m
Delta
Wed 5/134:25 pm
STL
- PWM
1 stop7h 18m
Delta
Deal found 3/21![Delta logo]()
$402
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
PWM
- SGF
1 stop5h 57m
American Airlines
Sat 5/3012:47 pm
SGF
- PWM
2 stops10h 04m
American Airlines
Deal found 3/19![American Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
PWM
- SGF
2 stops11h 26m
United Airlines
Sat 4/1111:23 am
SGF
- PWM
1 stop5h 09m
United Airlines
Deal found 3/21![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:50 pm
PWM
- STL
1 stop9h 35m
Southwest
Fri 5/154:00 pm
STL
- PWM
1 stop6h 25m
Southwest
Deal found 3/18![Southwest logo]()
$384
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:04 am
PWM
- SGF
1 stop5h 44m
United Airlines
Wed 4/83:10 pm
SGF
- PWM
1 stop5h 30m
United Airlines
Deal found 3/19![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:10 am
PWM
- STL
2 stops9h 55m
Southwest
Fri 5/154:00 pm
STL
- PWM
1 stop6h 25m
Southwest
Deal found 3/18![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:21 am
PWM
- SGF
1 stop6h 40m
Delta
Fri 5/83:22 pm
SGF
- PWM
1 stop6h 47m
Delta
Deal found 3/22![Delta logo]()
$453
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/54:50 pm
PWM
- STL
1 stop5h 23m
United Airlines
Wed 5/67:45 am
STL
- PWM
2 stops10h 19m
United Airlines
Deal found 3/19![United Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:50 pm
PWM
- STL
1 stop6h 15m
Southwest
Thu 4/94:00 pm
STL
- PWM
1 stop6h 25m
Southwest
Deal found 3/18![Southwest logo]()
$419
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:18 pm
PWM
- SGF
2 stops10h 01m
Delta
Fri 5/296:49 pm
SGF
- PWM
2 stops18h 09m
Delta
Deal found 3/22![Delta logo]()
$482
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:20 am
PWM
- MCI
1 stop6h 42m
United Airlines
Tue 5/196:17 am
MCI
- PWM
1 stop6h 57m
United Airlines
Deal found 3/22![United Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:18 pm
PWM
- SGF
2 stops10h 01m
Delta
Tue 5/266:49 pm
SGF
- PWM
2 stops18h 09m
Delta
Deal found 3/22![Delta logo]()
$497
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:30 pm
PWM
- MCI
1 stop6h 25m
Southwest
Wed 5/2012:20 pm
MCI
- PWM
2 stops9h 15m
Southwest
Deal found 3/21![Southwest logo]()
$452
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
PWM
- MCI
1 stop7h 24m
United Airlines
Tue 4/148:00 am
MCI
- PWM
1 stop5h 20m
United Airlines
Deal found 3/17![United Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:30 am
PWM
- MCI
2 stops10h 50m
Southwest
Sat 5/231:40 pm
MCI
- PWM
2 stops8h 30m
Southwest
Deal found 3/20![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:04 am
PWM
- SGF
1 stop5h 44m
United Airlines
Wed 4/88:00 am
SGF
- PWM
1 stop5h 20m
United Airlines
Deal found 3/20![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
PWM
- SGF
1 stop5h 48m
United Airlines
Sat 5/93:10 pm
SGF
- PWM
1 stop5h 09m
United Airlines
Deal found 3/22![United Airlines logo]()
$493
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
PWM
- SGF
2 stops12h 24m
United Airlines
Tue 4/146:00 am
SGF
- PWM
2 stops11h 37m
United Airlines
Deal found 3/20![United Airlines logo]()
$535
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:50 pm
PWM
- SGF
1 stop6h 12m
United Airlines
Thu 5/711:20 am
SGF
- PWM
2 stops11h 39m
United Airlines
Deal found 3/18![United Airlines logo]()
$550
Last-minute flights from Portland to MissouriDiscover last-minute flight deals from Portland to Missouri. Data last updated March 23, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Missouri. Data last updated March 23, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:04 am
PWM
- SGF
1 stop5h 44m
United Airlines
Wed 4/83:10 pm
SGF
- PWM
1 stop5h 30m
United Airlines
Deal found 3/19![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
PWM
- SGF
2 stops11h 26m
United Airlines
Sat 4/1111:23 am
SGF
- PWM
1 stop5h 09m
United Airlines
Deal found 3/21![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:10 am
PWM
- SGF
1 stop8h 37m
American Airlines
Tue 4/143:17 pm
SGF
- PWM
1 stop5h 56m
American Airlines
Deal found 3/20![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:03 am
PWM
- STL
1 stop7h 19m
Delta
Tue 4/146:48 am
STL
- PWM
1 stop4h 17m
Delta
Deal found 3/18![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:01 pm
PWM
- STL
1 stop5h 16m
American Airlines
Wed 4/156:35 am
STL
- PWM
1 stop7h 34m
American Airlines
Deal found 3/18![American Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:20 pm
PWM
- STL
1 stop8h 25m
Southwest
Wed 4/152:30 pm
STL
- PWM
2 stops7h 05m
Southwest
Deal found 3/18![Southwest logo]()
$384
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:01 pm
PWM
- STL
1 stop6h 45m
American Airlines
Wed 4/156:35 am
STL
- PWM
1 stop7h 34m
American Airlines
Deal found 3/19![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:50 pm
PWM
- STL
1 stop7h 35m
Southwest
Wed 4/151:45 pm
STL
- PWM
2 stops7h 50m
Southwest
Deal found 3/19![Southwest logo]()
$320
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
PWM
- STL
1 stop7h 48m
American Airlines
Mon 4/205:21 pm
STL
- PWM
1 stop5h 06m
American Airlines
Deal found 3/18![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:33 pm
PWM
- STL
1 stop5h 38m
United Airlines
Sat 4/189:16 am
STL
- PWM
2 stops8h 24m
United Airlines
Deal found 3/21![United Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:01 pm
PWM
- MCI
1 stop6h 58m
American Airlines
Tue 5/54:51 pm
MCI
- PWM
1 stop5h 36m
American Airlines
Deal found 3/20![American Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:50 pm
PWM
- MCI
1 stop7h 41m
United Airlines
Tue 5/53:22 pm
MCI
- PWM
2 stops7h 37m
United Airlines
Deal found 3/20![United Airlines logo]()
$345
One-way flights from Portland to MissouriSearch for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
Search for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:29 am
PWM
- STL
2 stops46h 26m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$143
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:21 am
PWM
- STL
1 stop6h 13m
Delta
Deal found 3/18![Delta logo]()
$150
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:26 pm
PWM
- MCI
1 stop5h 55m
Delta
Deal found 3/18![Delta logo]()
$157
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:34 am
PWM
- STL
1 stop7h 42m
United Airlines
Deal found 3/18![United Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:29 am
PWM
- STL
2 stops20h 21m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:18 pm
PWM
- STL
2 stops37h 32m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$177
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:33 pm
PWM
- STL
1 stop5h 38m
United Airlines
Deal found 3/21![United Airlines logo]()
$189
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
PWM
- STL
1 stop7h 11m
United Airlines
Deal found 3/18![United Airlines logo]()
$190
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:08 am
PWM
- STL
2 stops11h 05m
United Airlines
Deal found 3/18![United Airlines logo]()
$195
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
PWM
- STL
1 stop7h 05m
Delta
Deal found 3/18![Delta logo]()
$200
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:15 am
PWM
- STL
2 stops8h 34m
United Airlines
Deal found 3/19![United Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:29 am
PWM
- UIN
3 stops29h 36m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$205
Find flight deals from Portland to Missouri
Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated March 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
One-way from | $143 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $344 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKansas City
PWM - MCI
PWMMCI
Portland
Thu 4/30
4:50 pm-11:31 pm
1 stop7h 41m
Kansas City
Tue 5/5
3:22 pm-11:59 pm
2 stops7h 37m
$345
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Mon 5/11
5:30 am-10:50 am
1 stop6h 20m
Lambert-St Louis
Tue 5/12
6:35 am-12:20 pm
1 stop4h 45m
$379
PortlandSpringfield
PWM - SGF
PWMSGF
Portland
Sat 4/4
6:00 am-4:26 pm
2 stops11h 26m
Springfield-Branson
Sat 4/11
11:23 am-5:32 pm
1 stop5h 09m
$379
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Thu 5/14
2:50 pm-11:25 pm
1 stop9h 35m
Lambert-St Louis
Fri 5/15
4:00 pm-11:25 pm
1 stop6h 25m
$384
PortlandSpringfield
PWM - SGF
PWMSGF
Portland
Fri 4/3
6:04 am-10:48 am
1 stop5h 44m
Springfield-Branson
Wed 4/8
3:10 pm-9:40 pm
1 stop5h 30m
$399
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Thu 5/7
11:03 am-3:40 pm
1 stop5h 37m
Lambert-St Louis
Wed 5/13
4:25 pm-12:43 am
1 stop7h 18m
$402
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Wed 5/13
6:10 am-3:05 pm
2 stops9h 55m
Lambert-St Louis
Fri 5/15
4:00 pm-11:25 pm
1 stop6h 25m
$407
PortlandSt. Louis
PWM - STL
PWMSTL
Portland
Tue 5/5
4:50 pm-9:13 pm
1 stop5h 23m
Lambert-St Louis
Wed 5/6
7:45 am-7:04 pm
2 stops10h 19m
$410
PortlandSpringfield
PWM - SGF
PWMSGF
Portland
Sat 5/23
6:00 am-10:57 am
1 stop5h 57m
Springfield-Branson
Sat 5/30
12:47 pm-11:51 pm
2 stops10h 04m
$414
PortlandKansas City
PWM - MCI
PWMMCI
Portland
Sat 5/9
9:20 am-3:02 pm
1 stop6h 42m
Kansas City
Tue 5/19
6:17 am-2:14 pm
1 stop6h 57m
$417
Showing 1-10 of 45 resultsSorted by cheapest first
Best time to book a flight from Portland to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
PWM-STL
PWM-MCI
PWM-SGF
PWM-UIN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Missouri
PWM-USMO
PWM-STL
PWM-MCI
PWM-SGF
PWM-UIN
What is the cheapest month to book a flight from Portland, Maine to Missouri?
Currently, March is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $133). Flying from Portland, Maine to Missouri in June is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 23, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Missouri
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Complete your trip
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Search flights from Portland to Missouri by cabin class
Find flights from Portland to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Missouri flights
Browse other Portland and Missouri flight options. Last updated on March 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Missouri flights
Consider these flights traveling from Portland to Missouri.
Top 4 airlines flying from Portland to Missouri
Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$413 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$237 | Average$461 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$243 | Average$469 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$267 | Average$483 | FlexibilityNo cancel fee | On-time69% |