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Missouri

$294+ Cheap flights from Portland, ME (PWM) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MCI
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Portland to Missouri

Cheapest flights from Portland to Missouri
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:30 amPWM - STL
2 stops7h 57mUnited Airlines
Sat 1/36:30 amSTL - PWM
1 stop6h 44mUnited Airlines
Deal found 12/15$507
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:45 amPWM - STL
2 stops12h 15mDelta
Thu 12/2510:04 amSTL - PWM
2 stops11h 39mDelta
Deal found 12/15$509
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:45 amPWM - STL
1 stop7h 36mDelta
Sat 1/37:10 amSTL - PWM
1 stop7h 50mDelta
Deal found 12/15$533
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:19 amPWM - MCI
1 stop5h 41mUnited Airlines
Sun 1/45:46 pmMCI - PWM
1 stop5h 13mUnited Airlines
Deal found 12/12$533
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:01 pmPWM - STL
1 stop5h 56mUnited Airlines
Thu 12/258:15 amSTL - PWM
1 stop5h 25mUnited Airlines
Deal found 12/15$579
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:30 pmPWM - MCI
2 stops27h 20mUnited Airlines
Sat 1/37:40 amMCI - PWM
1 stop5h 34mUnited Airlines
Deal found 12/15$656
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:30 amPWM - MCI
1 stop6h 08mUnited Airlines
Thu 12/255:46 pmMCI - PWM
1 stop5h 13mUnited Airlines
Deal found 12/15$706
This Southwest deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:30 amPWM - MCI
2 stops9h 00mSouthwest
Sun 1/45:00 amMCI - PWM
2 stops8h 40mSouthwest
Deal found 12/12$729
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:30 pmPWM - MCI
2 stops27h 20mUnited Airlines
Fri 12/267:40 amMCI - PWM
1 stop5h 34mUnited Airlines
Deal found 12/15$766
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:45 amPWM - MCI
1 stop6h 58mDelta
Sat 1/36:30 amMCI - PWM
1 stop4h 42mDelta
Deal found 12/13$768
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:30 amPWM - SGF
2 stops11h 52mUnited Airlines
Sat 1/36:20 pmSGF - PWM
2 stops28h 02mUnited Airlines
Deal found 12/13$768
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:45 amPWM - MCI
1 stop6h 58mDelta
Fri 1/26:30 amMCI - PWM
1 stop4h 46mDelta
Deal found 12/13$778

Find flight deals from Portland to Missouri

Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$294
(United Airlines)

Popular in

April

Cheapest in

August

Average price

$461
Provider with most accurate pricing for Boston Logan Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Lambert-St Louis flights.
Search Deals
From Portland to Missouri
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.

Fly from

Portland

Fly to

Missouri

Route

Depart

Return

Price

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Thu 1/8

6:00 am-2:38 pm

2 stops9h 38m

Springfield-Branson

Sat 1/10

7:45 am-2:39 pm

1 stop5h 54m

$294

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Tue 2/10

5:30 am-11:20 am

1 stop6h 50m

Springfield-Branson

Tue 2/24

6:00 am-5:14 pm

2 stops10h 14m

$294

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Thu 1/8

7:00 am-12:15 pm

1 stop6h 15m

Springfield-Branson

Sat 1/10

12:45 pm-10:07 pm

1 stop8h 22m

$314

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 2/11

3:58 pm-9:06 pm

1 stop6h 08m

Kansas City

Wed 2/18

10:58 am-10:16 pm

2 stops10h 18m

$328

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/22

12:45 pm-7:00 pm

1 stop7h 15m

Lambert-St Louis

Mon 1/26

2:35 pm-10:15 pm

1 stop6h 40m

$335

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

6:00 am-11:41 am

1 stop6h 41m

Lambert-St Louis

Tue 1/13

9:33 am-3:31 pm

1 stop4h 58m

$335

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/22

12:45 pm-7:00 pm

1 stop7h 15m

Lambert-St Louis

Tue 1/27

2:15 pm-10:15 pm

2 stops7h 00m

$340

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

6:00 am-5:50 pm

2 stops12h 50m

Lambert-St Louis

Mon 1/12

3:45 pm-10:27 pm

1 stop5h 42m

$340

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

6:00 am-5:50 pm

2 stops12h 50m

Lambert-St Louis

Tue 1/13

6:35 am-12:08 pm

1 stop4h 33m

$340

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Tue 2/17

5:31 am-10:38 am

1 stop6h 07m

Kansas City

Mon 2/23

5:15 pm-11:51 pm

1 stop5h 36m

$351

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 23 results
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Best time to book a flight from Portland to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Missouri

What is the cheapest month to book a flight from Portland, Maine to Missouri?

Currently, December is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $107). Flying from Portland, Maine to Missouri in June is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to MO?

Find hourly flight availability from Portland to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from Portland, Maine to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 40% versus a flight in the morning.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 15, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Portland to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,007 reviews
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,092 reviews
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,052 reviews
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Missouri?

    Located just 2.9 mi from the city center, Portland (PWM) is the airport most travelers will use when flying to Missouri from Portland.

  • How long is the flight from Portland, Maine to Missouri?

    There are many flights that can get you from Portland, Maine to Missouri in 6h 15m. Fly via United Airlines, Delta, or American Airlines to get the fastest option. Portland, Maine and Missouri are separated by a distance of 1285 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland, Maine to Missouri one-way?

    One-way options have recently been found by users for as low as $128 on Delta. Other airlines that offer cheap prices include American Airlines from $154 and Southwest from $168 one-way.

  • What are the most popular routes from Portland, Maine to Missouri?

    When deciding which route to take from Portland, Maine to Missouri consider Portland - Springfield-Branson, Portland - Kansas City or Portland - Lambert-St Louis as they are the most popular.

  • Can I find deals for flights from Portland to Missouri that include hotel bookings?

    Yes. In addition to deals on Portland to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Missouri.

  • Can I find deals for business class flights from Portland to Missouri?

    Yes. Cheapflights offers flight deals from Portland to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Missouri?

    Currently, December is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $107). Flying from Portland, Maine to Missouri in June is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to Missouri

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Top 4 airlines flying from Portland to Missouri

Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$173Average$400FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$237Average$402FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$243Average$470FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$267Average$657FlexibilityNo cancel feeOn-time69%

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