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Missouri

$157+ Cheap flights from Portland, ME (PWM) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Portland to Missouri

Cheapest flights from Portland to Missouri
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:31 am
PWM
-
SGF
1 stop6h 49m
Delta
Mon 3/93:56 pm
SGF
-
PWM
1 stop6h 26m
Delta
Deal found 1/27$289
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:35 pm
PWM
-
SGF
2 stops8h 12m
Delta
Tue 3/103:56 pm
SGF
-
PWM
1 stop6h 26m
Delta
Deal found 1/27$294
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:31 am
PWM
-
SGF
1 stop6h 49m
Delta
Wed 3/113:56 pm
SGF
-
PWM
1 stop6h 26m
Delta
Deal found 1/27$309
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:07 am
PWM
-
STL
1 stop7h 52m
American Airlines
Tue 4/146:00 am
STL
-
PWM
1 stop16h 10m
American Airlines
Deal found 1/28$315
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:40 pm
PWM
-
SGF
1 stop5h 51m
American Airlines
Tue 3/102:19 pm
SGF
-
PWM
2 stops8h 36m
American Airlines
Deal found 1/27$319
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:50 pm
PWM
-
STL
2 stops9h 05m
Southwest
Tue 4/146:35 am
STL
-
PWM
1 stop4h 45m
Southwest
Deal found 1/28$322
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:07 pm
PWM
-
MCI
1 stop6h 53m
American Airlines
Sat 3/75:15 am
MCI
-
PWM
1 stop5h 44m
American Airlines
Deal found 1/28$332
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:45 pm
PWM
-
STL
1 stop7h 03m
American Airlines
Mon 4/207:05 am
STL
-
PWM
1 stop9h 10m
American Airlines
Deal found 1/27$334
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:31 am
PWM
-
SGF
1 stop6h 49m
Delta
Mon 3/93:56 pm
SGF
-
PWM
1 stop6h 26m
Delta
Deal found 1/27$334
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:50 pm
PWM
-
STL
1 stop7h 35m
Southwest
Sat 2/285:05 am
STL
-
PWM
1 stop4h 50m
Southwest
Deal found 1/26$335
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:27 pm
PWM
-
STL
1 stop5h 32m
United Airlines
Wed 2/117:00 am
STL
-
PWM
1 stop5h 56m
United Airlines
Deal found 1/27$339
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:30 am
PWM
-
MCI
1 stop8h 15m
Southwest
Thu 3/55:20 am
MCI
-
PWM
1 stop5h 35m
Southwest
Deal found 1/27$339

Find flight deals from Portland to Missouri

Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(Delta)

One-way from

$157
(American Airlines)

Popular in

November

Cheapest in

February

Average price

$487
Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.
Search Deals
From Portland to Missouri
Search Deals
One-way flight from Portland to Missouri
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.

Fly from

Portland

Fly to

Missouri

Route

Depart

Return

Price

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Sun 3/1

5:31 am-11:20 am

1 stop6h 49m

Springfield-Branson

Tue 3/10

3:56 pm-11:22 pm

1 stop6h 26m

$289

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Tue 2/24

5:31 am-11:20 am

1 stop6h 49m

Springfield-Branson

Tue 3/10

3:56 pm-11:22 pm

1 stop6h 26m

$289

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Tue 2/24

5:31 am-11:20 am

1 stop6h 49m

Springfield-Branson

Mon 3/9

3:56 pm-11:22 pm

1 stop6h 26m

$289

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Sun 3/1

5:31 am-11:20 am

1 stop6h 49m

Springfield-Branson

Mon 3/9

3:56 pm-11:22 pm

1 stop6h 26m

$289

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Thu 2/26

6:00 am-4:47 pm

2 stops11h 47m

Springfield-Branson

Tue 3/10

3:56 pm-11:22 pm

1 stop6h 26m

$294

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Tue 2/24

5:31 am-11:20 am

1 stop6h 49m

Springfield-Branson

Wed 3/11

3:56 pm-11:22 pm

1 stop6h 26m

$309

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Thu 2/26

6:00 am-4:47 pm

2 stops11h 47m

Springfield-Branson

Wed 3/11

3:56 pm-11:22 pm

1 stop6h 26m

$314

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 4/9

2:50 pm-10:55 pm

2 stops9h 05m

Lambert-St Louis

Tue 4/14

6:35 am-12:20 pm

1 stop4h 45m

$322

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 3/4

7:00 am-12:27 pm

1 stop6h 27m

Kansas City

Sat 3/7

5:15 am-11:59 am

1 stop5h 44m

$332

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 4/15

5:45 pm-11:48 pm

1 stop7h 03m

Lambert-St Louis

Mon 4/20

7:05 am-5:15 pm

1 stop9h 10m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 34 results
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Best time to book a flight from Portland to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Missouri

What is the cheapest month to book a flight from Portland, Maine to Missouri?

Currently, October is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $161). Flying from Portland, Maine to Missouri in June is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 29, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Portland to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Missouri?

    Located just 2.9 mi from the city center, Portland (PWM) is the airport most travelers will use when flying to Missouri from Portland.

  • How long is the flight from Portland, Maine to Missouri?

    There are many flights that can get you from Portland, Maine to Missouri in 6h 27m. Fly via Delta, Southwest, or American Airlines to get the fastest option. Portland, Maine and Missouri are separated by a distance of 1293 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland, Maine to Missouri one-way?

    One-way options have recently been found by users for as low as $128 on Delta. Other airlines that offer cheap prices include American Airlines from $154 and United Airlines from $158 one-way.

  • What are the most popular routes from Portland, Maine to Missouri?

    When deciding which route to take from Portland, Maine to Missouri consider Portland - Kansas City, Portland - Springfield-Branson or Portland - Lambert-St Louis as they are the most popular.

  • Can I find deals for flights from Portland to Missouri that include hotel bookings?

    Yes. In addition to deals on Portland to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Missouri.

  • Can I find deals for business class flights from Portland to Missouri?

    Yes. Cheapflights offers flight deals from Portland to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Missouri?

    Currently, October is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $161). Flying from Portland, Maine to Missouri in June is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to Missouri

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Top 4 airlines flying from Portland to Missouri

Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$158Average$362FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$237Average$402FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$243Average$480FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$267Average$525FlexibilityNo cancel feeOn-time69%

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