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$116+ Cheap flights from Portland, ME (PWM) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Portland to Missouri

Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated April 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$285
(American Airlines)

One-way from

$116
(Mytrip)

Popular in

April

Cheapest in

January

Average price

$780
Provider with most accurate pricing for Portland-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Portland-Kansas City flights.
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From Portland to Missouri
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One-way flight from Portland to Missouri
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Highest demand for flights based on searches. 15% potential increase in price ($85 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Portland to Missouri

Cheapest flights from Portland to Missouri
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/234:49 pmPWM - SGF
1 stop6h 41mAmerican Airlines
Sat 8/308:23 amSGF - PWM
1 stop6h 36mAmerican Airlines
Deal found 4/28$269
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/215:50 amPWM - STL
1 stop4h 52mAmerican Airlines
Wed 5/2810:25 amSTL - PWM
1 stop5h 26mAmerican Airlines
Deal found 4/28$285
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/281:40 pmPWM - STL
2 stops10h 58mDelta
Wed 6/43:40 pmSTL - PWM
1 stop6h 41mDelta
Deal found 4/28$290
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:10 amPWM - SGF
1 stop5h 40mUnited Airlines
Sat 8/307:55 amSGF - PWM
2 stops10h 34mUnited Airlines
Deal found 4/28$297
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:30 amPWM - MCI
1 stop7h 40mDelta
Tue 6/33:48 pmMCI - PWM
1 stop7h 11mDelta
Deal found 4/28$299
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:00 amPWM - MCI
1 stop8h 08mAmerican Airlines
Sun 6/15:45 pmMCI - PWM
1 stop5h 10mAmerican Airlines
Deal found 4/29$353
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/55:40 amPWM - MCI
1 stop5h 30mSouthwest
Tue 6/106:45 amMCI - PWM
2 stops7h 40mSouthwest
Deal found 4/28$367
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:15 amPWM - STL
1 stop7h 05mSouthwest
Sat 5/3112:20 pmSTL - PWM
2 stops10h 05mSouthwest
Deal found 4/28$381
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2812:15 pmPWM - MCI
2 stops12h 14mUnited Airlines
Tue 6/36:00 amMCI - PWM
2 stops10h 43mUnited Airlines
Deal found 4/28$407
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1212:55 pmPWM - SGF
1 stop6h 16mDelta
Sat 6/1411:25 amSGF - PWM
1 stop5h 08mDelta
Deal found 4/28$439
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2412:15 pmPWM - STL
2 stops11h 30mUnited Airlines
Sat 6/287:55 amSTL - PWM
2 stops9h 18mUnited Airlines
Deal found 4/28$508
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1911:50 amPWM - STL
3 stops31h 51mMultiple Airlines
Thu 5/2210:10 amSTL - PWM
2 stops26h 57mMultiple Airlines
Deal found 4/29$599

Cheapflights Fare Finder

Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.

Fly from

Portland

Fly to

Missouri

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/21

5:50 am-9:42 am

1 stop4h 52m

Lambert-St Louis

Wed 5/28

10:25 am-4:51 pm

1 stop5h 26m

$285

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/28

1:40 pm-11:38 pm

2 stops10h 58m

Lambert-St Louis

Wed 6/4

3:40 pm-11:21 pm

1 stop6h 41m

$290

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 5/28

5:30 am-12:10 pm

1 stop7h 40m

Kansas City

Tue 6/3

3:48 pm-11:59 pm

1 stop7h 11m

$299

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Tue 5/27

6:00 am-1:08 pm

1 stop8h 08m

Kansas City

Sun 6/1

5:45 pm-11:55 pm

1 stop5h 10m

$353

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Thu 6/5

5:40 am-10:10 am

1 stop5h 30m

Kansas City

Tue 6/10

6:45 am-3:25 pm

2 stops7h 40m

$367

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/28

6:15 am-12:20 pm

1 stop7h 05m

Lambert-St Louis

Sat 5/31

12:20 pm-11:25 pm

2 stops10h 05m

$381

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 5/28

12:15 pm-11:29 pm

2 stops12h 14m

Kansas City

Tue 6/3

6:00 am-5:43 pm

2 stops10h 43m

$407

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Fri 5/2

4:16 pm-11:54 pm

2 stops8h 38m

Springfield-Branson

Tue 5/6

4:09 pm-11:05 pm

1 stop5h 56m

$414

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Sat 5/24

6:00 am-10:51 am

1 stop5h 51m

Springfield-Branson

Mon 6/2

6:39 pm-9:56 pm

1 stop26h 17m

$433

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Thu 6/12

12:55 pm-6:11 pm

1 stop6h 16m

Springfield-Branson

Sat 6/14

11:25 am-5:33 pm

1 stop5h 08m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 21 results
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Best time to book a flight from Portland to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Missouri

What is the cheapest month to book a flight from Portland, Maine to Missouri?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to MO?

Find hourly flight availability from Portland to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from Portland, Maine to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 30, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Portland to Missouri to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,936 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Frontier
6.0
Okay
3,287 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Missouri?

    Located just 2.9 mi from the city center, Portland (PWM) is the airport most travelers will use when flying to Missouri from Portland.

  • What are the cheapest airlines to fly from Portland, Maine to Missouri one-way?

    One-way options have recently been found by users for as low as $116 on Frontier. Other airlines that offer cheap prices include Delta from $168 and Southwest from $173 one-way.

  • What are the most popular routes from Portland, Maine to Missouri?

    When deciding which route to take from Portland, Maine to Missouri consider Portland - Lambert-St Louis, Portland - Springfield-Branson or Portland - Kansas City as they are the most popular.

  • Can I find deals for flights from Portland to Missouri that include hotel bookings?

    Yes. In addition to deals on Portland to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Missouri.

  • Can I find deals for business class flights from Portland to Missouri?

    Yes. Cheapflights offers flight deals from Portland to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Portland to Missouri

Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$442FlexibilityNo cancel feeOn-time71%
DeltaCheapest$255Average$412FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$267Average$532FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$351Average$509FlexibilityNo cancel feeOn-time63%

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