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$256+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Dec 22 — Dec 291
Mon 12/22
Mon 12/29
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated November 22, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$256
(Delta)

Popular in

November

Cheapest in

August

Average price

$772
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
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From Medford to Missouri
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Highest demand for flights based on searches. 16% potential increase in price ($105 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 22, 2025.

This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:50 pmMFR - COU
1 stop5h 39mUnited Airlines
Tue 12/99:00 amCOU - MFR
2 stops10h 52mUnited Airlines
Deal found 11/19$336
This Alaska Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:28 pmMFR - STL
1 stop6h 31mAlaska Airlines
Sat 1/106:19 pmSTL - MFR
1 stop7h 37mAlaska Airlines
Deal found 11/19$342
This Alaska Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:28 pmMFR - STL
1 stop6h 31mAlaska Airlines
Tue 1/132:50 pmSTL - MFR
1 stop11h 06mAlaska Airlines
Deal found 11/19$343
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:36 pmMFR - STL
2 stops18h 48mDelta
Wed 1/73:40 pmSTL - MFR
2 stops9h 19mDelta
Deal found 11/19$345
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:37 pmMFR - STL
1 stop5h 57mDelta
Tue 1/1311:23 amSTL - MFR
2 stops13h 36mDelta
Deal found 11/19$347
This Alaska Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:28 pmMFR - STL
1 stop6h 31mAlaska Airlines
Wed 1/77:00 amSTL - MFR
2 stops17h 49mAlaska Airlines
Deal found 11/19$348
This Alaska Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:28 pmMFR - STL
1 stop6h 31mAlaska Airlines
Fri 1/92:50 pmSTL - MFR
1 stop28h 12mAlaska Airlines
Deal found 11/19$353
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:36 pmMFR - STL
2 stops20h 36mDelta
Wed 1/77:00 amSTL - MFR
1 stop7h 25mDelta
Deal found 11/19$358
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:36 pmMFR - STL
2 stops20h 36mDelta
Mon 1/123:40 pmSTL - MFR
2 stops9h 19mDelta
Deal found 11/19$361
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:37 pmMFR - STL
1 stop5h 57mDelta
Thu 1/87:00 amSTL - MFR
2 stops17h 59mDelta
Deal found 11/19$363
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:00 amMFR - STL
1 stop6h 23mDelta
Fri 1/97:00 amSTL - MFR
2 stops11h 40mDelta
Deal found 11/19$367
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:36 pmMFR - STL
2 stops20h 36mDelta
Thu 1/87:00 amSTL - MFR
1 stop7h 25mDelta
Deal found 11/19$377

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 22, 2025.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/20

12:05 pm-11:25 pm

2 stops9h 20m

Lambert-St Louis

Tue 2/10

6:40 am-4:40 pm

2 stops12h 00m

$256

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 2/21

6:05 am-9:38 pm

2 stops13h 33m

Lambert-St Louis

Wed 2/25

2:22 pm-10:57 am

2 stops22h 35m

$256

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Wed 1/7

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Sat 1/10

7:00 am-10:59 pm

2 stops17h 59m

$256

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Tue 1/13

6:35 am-4:40 pm

2 stops12h 05m

$256

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 1/8

6:05 am-11:25 pm

2 stops15h 20m

Lambert-St Louis

Sat 1/10

7:00 am-12:25 pm

1 stop7h 25m

$269

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sat 2/21

1:00 pm-8:40 pm

1 stop5h 40m

Kansas City

Tue 2/24

6:30 am-12:20 pm

1 stop7h 50m

$283

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Wed 1/7

3:40 pm-10:59 pm

2 stops9h 19m

$294

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Mon 1/5

6:05 am-11:23 pm

2 stops15h 18m

Lambert-St Louis

Tue 1/13

3:40 pm-10:59 pm

2 stops9h 19m

$296

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 2/21

5:45 am-1:51 pm

1 stop6h 06m

Lambert-St Louis

Wed 2/25

7:00 am-1:02 pm

1 stop8h 02m

$304

MedfordColumbia

MFR - COU

MFRCOU

Medford

Sat 12/6

12:50 pm-8:29 pm

1 stop5h 39m

Columbia Regional

Tue 12/9

9:00 am-5:52 pm

2 stops10h 52m

$336

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/21

Showing 1-10 of 15 results
1
2

Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 22, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,329 reviews

Crew

8.5

Boarding

8.1

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
Alaska Airlines
8.0
Very good
11,329 reviews
Alaska Airlines
8.0
Very good
11,329 reviews

Crew

8.5

Boarding

8.1

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
Delta
7.9
Good
8,002 reviews
Alaska Airlines
8.0
Very good
11,329 reviews

Crew

8.5

Boarding

8.1

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
United Airlines
7.4
Good
9,035 reviews
Alaska Airlines
8.0
Very good
11,329 reviews

Crew

8.5

Boarding

8.1

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
American Airlines
7.2
Good
11,048 reviews
Alaska Airlines
8.0
Very good
11,329 reviews

Crew

8.5

Boarding

8.1

Food

7.1

Entertainment

7.0

Overall

8.0

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 5h 39m. Delta provides one of the quickest options available for as low as $336. Medford and Missouri are separated by a distance of 1617 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Kansas City or Medford - Joplin, Medford - Lambert-St Louis is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Medford to Missouri

Discover the top 4 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$485FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$346FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$318Average$589FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$377Average$411FlexibilityNo cancel feeOn-time71%

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