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$143+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Feb 6 — Feb 131
Fri 2/6
Fri 2/13
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated January 7, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$241
(Alaska Airlines)

One-way from

$143
(Alaska Airlines)

Popular in

December

Cheapest in

August

Average price

$682
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
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From Medford to Missouri
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One-way flight from Medford to Missouri
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Highest demand for flights based on searches. 27% potential increase in price ($228 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

This Alaska Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:40 amMFR - MCI
1 stop6h 42mAlaska Airlines
Tue 3/175:16 pmMCI - MFR
1 stop20h 38mAlaska Airlines
Deal found 1/6$241
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:45 amMFR - MCI
1 stop6h 10mAlaska Airlines
Wed 3/182:23 pmMCI - MFR
1 stop6h 47mAlaska Airlines
Deal found 1/6$244
This Alaska Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:41 pmMFR - MCI
1 stop22h 14mAlaska Airlines
Wed 3/186:15 amMCI - MFR
1 stop14h 55mAlaska Airlines
Deal found 1/6$245
This Orbitz deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:45 pmMFR - MCI
2 stops19h 37mAlaska Airlines
Tue 3/175:16 pmMCI - MFR
1 stop24h 18mAlaska Airlines
Deal found 1/6$253
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/303:00 pmMFR - MCI
1 stop6h 59mAmerican Airlines
Tue 2/38:00 amMCI - MFR
1 stop7h 07mAmerican Airlines
Deal found 1/4$264
This Alaska Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/53:45 pmMFR - MCI
1 stop21h 20mAlaska Airlines
Sun 2/83:59 pmMCI - MFR
1 stop26h 09mAlaska Airlines
Deal found 1/5$265
This United Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:25 pmMFR - MCI
2 stops14h 07mUnited Airlines
Tue 2/39:05 amMCI - MFR
1 stop6h 14mUnited Airlines
Deal found 1/4$269
This Alaska Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:45 pmMFR - STL
1 stop27h 14mAlaska Airlines
Fri 3/67:00 amSTL - MFR
1 stop12h 07mAlaska Airlines
Deal found 1/7$289
This Alaska Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/275:42 amMFR - STL
1 stop6h 12mAlaska Airlines
Fri 1/302:50 pmSTL - MFR
1 stop11h 06mAlaska Airlines
Deal found 1/6$291
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2612:05 pmMFR - STL
2 stops9h 20mDelta
Sat 1/313:31 pmSTL - MFR
2 stops9h 28mDelta
Deal found 1/7$330
This Alaska Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/263:45 pmMFR - STL
2 stops20h 09mAlaska Airlines
Fri 1/302:50 pmSTL - MFR
1 stop28h 12mAlaska Airlines
Deal found 1/6$341
This Alaska Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/263:45 pmMFR - STL
2 stops20h 09mAlaska Airlines
Sun 2/12:50 pmSTL - MFR
2 stops23h 07mAlaska Airlines
Deal found 1/6$356

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 3/10

7:40 am-4:22 pm

1 stop6h 42m

Kansas City

Tue 3/17

5:16 pm-11:54 am

1 stop20h 38m

$241

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Wed 3/11

5:45 am-1:55 pm

1 stop6h 10m

Kansas City

Wed 3/18

2:23 pm-7:10 pm

1 stop6h 47m

$244

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Wed 3/11

3:38 pm-4:22 pm

1 stop22h 44m

Kansas City

Mon 3/16

5:16 pm-7:48 pm

1 stop28h 32m

$245

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Wed 3/11

5:45 am-1:55 pm

1 stop6h 10m

Kansas City

Tue 3/17

5:16 pm-11:54 am

1 stop20h 38m

$260

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 2/5

3:45 pm-3:05 pm

1 stop21h 20m

Kansas City

Sun 2/8

3:59 pm-4:08 pm

1 stop26h 09m

$265

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 1/30

6:25 pm-10:32 am

2 stops14h 07m

Kansas City

Tue 2/3

9:05 am-1:19 pm

1 stop6h 14m

$269

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Wed 4/8

1:22 pm-11:59 pm

1 stop8h 37m

Kansas City

Sat 4/11

5:36 pm-10:59 pm

1 stop7h 23m

$275

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 2/5

9:21 pm-11:33 pm

1 stop24h 12m

Kansas City

Sun 2/8

7:00 am-2:42 pm

1 stop9h 42m

$276

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 3/10

7:40 am-4:22 pm

1 stop6h 42m

Kansas City

Wed 3/18

6:15 am-3:34 pm

2 stops11h 19m

$281

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/27

5:42 am-1:54 pm

1 stop6h 12m

Lambert-St Louis

Fri 1/30

2:50 pm-11:56 pm

1 stop11h 06m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 30 results
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2
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Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 7, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,658 reviews

Crew

8.5

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Alaska Airlines
8.0
Very good
11,658 reviews
Alaska Airlines
8.0
Very good
11,658 reviews

Crew

8.5

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Delta
7.9
Good
8,021 reviews
Alaska Airlines
8.0
Very good
11,658 reviews

Crew

8.5

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
United Airlines
7.4
Good
9,138 reviews
Alaska Airlines
8.0
Very good
11,658 reviews

Crew

8.5

Entertainment

7.0

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 6h 42m. Alaska Airlines provides one of the quickest options available for as low as $241. Medford and Missouri are separated by a distance of 1479 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Columbia Regional, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Medford to Missouri

Discover the top 3 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$476FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$390FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$308Average$577FlexibilityNo cancel feeOn-time69%

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