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$256+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$256
(Delta)

Popular in

November

Cheapest in

August

Average price

$772
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
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From Medford to Missouri
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Highest demand for flights based on searches. 16% potential increase in price ($105 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Mytrip deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:56 pmMFR - MCI
1 stop14h 56mMultiple Airlines
Thu 12/187:00 amMCI - MFR
1 stop10h 17mMultiple Airlines
Deal found 11/25$288
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:24 amMFR - MCI
1 stop7h 20mMultiple Airlines
Thu 12/187:00 amMCI - MFR
1 stop10h 17mMultiple Airlines
Deal found 11/25$329
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:00 amMFR - COU
2 stops10h 29mUnited Airlines
Sat 12/139:00 amCOU - MFR
1 stop6h 23mUnited Airlines
Deal found 11/24$354
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:56 pmMFR - MCI
1 stop14h 56mMultiple Airlines
Sat 12/208:45 pmMCI - MFR
2 stops20h 32mMultiple Airlines
Deal found 11/25$366
This KAYAK deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:45 amMFR - STL
1 stop6h 42mAlaska Airlines
Wed 12/245:26 pmSTL - MFR
1 stop8h 33mAlaska Airlines
Deal found 11/23$367
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:00 amMFR - MCI
1 stop6h 27mDelta
Tue 12/166:28 amMCI - MFR
1 stop7h 33mDelta
Deal found 11/25$371
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:24 amMFR - MCI
1 stop7h 20mMultiple Airlines
Sat 12/208:45 pmMCI - MFR
2 stops20h 32mMultiple Airlines
Deal found 11/25$372
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:00 amMFR - MCI
1 stop6h 27mDelta
Thu 12/186:22 pmMCI - MFR
1 stop7h 37mDelta
Deal found 11/25$381
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:14 amMFR - MCI
1 stop5h 26mAlaska Airlines
Wed 12/171:34 pmMCI - MFR
1 stop8h 02mAlaska Airlines
Deal found 11/25$383
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:40 amMFR - MCI
2 stops10h 49mDelta
Thu 12/186:22 pmMCI - MFR
1 stop7h 37mDelta
Deal found 11/25$386
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/168:00 amMFR - STL
2 stops12h 45mUnited Airlines
Wed 12/242:45 pmSTL - MFR
1 stop8h 27mUnited Airlines
Deal found 11/23$416
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:50 pmMFR - COU
1 stop5h 39mUnited Airlines
Tue 12/99:00 amCOU - MFR
1 stop6h 23mUnited Airlines
Deal found 11/23$483

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 2/21

6:15 am-9:38 pm

2 stops13h 23m

Lambert-St Louis

Wed 2/25

2:22 pm-11:12 pm

2 stops10h 50m

$256

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Tue 1/13

7:00 am-4:40 pm

2 stops11h 40m

$256

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sat 2/21

5:55 am-1:24 pm

1 stop5h 29m

Kansas City

Tue 2/24

6:30 am-12:16 pm

1 stop7h 46m

$283

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Wed 1/21

5:05 am-1:58 pm

1 stop6h 53m

Kansas City

Sun 1/25

7:00 am-10:59 pm

1 stop17h 59m

$285

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 1/23

6:05 am-11:23 pm

1 stop15h 18m

Kansas City

Sat 1/24

6:30 am-12:25 pm

1 stop7h 55m

$285

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 1/22

5:42 pm-1:50 pm

1 stop18h 08m

Kansas City

Mon 1/26

2:45 pm-12:43 pm

1 stop23h 58m

$287

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 1/22

12:05 pm-11:27 pm

2 stops9h 22m

Kansas City

Sat 1/24

2:53 pm-10:59 pm

2 stops10h 06m

$298

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 2/21

5:45 am-1:51 pm

1 stop6h 06m

Lambert-St Louis

Wed 2/25

7:00 am-1:02 pm

1 stop8h 02m

$304

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

3:00 pm-11:59 pm

1 stop6h 59m

Lambert-St Louis

Tue 1/13

2:38 pm-7:38 pm

1 stop7h 00m

$342

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 1/22

2:27 pm-11:59 pm

1 stop7h 32m

Lambert-St Louis

Sat 1/24

7:43 am-1:07 pm

1 stop7h 24m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Showing 1-10 of 17 results
1
2

Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 26, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,352 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.0

Food

7.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Nov 2025

LAX - LIH

The staff were exceptional! They all were kind, accommodating, and professional.
Alaska Airlines
8.0
Very good
11,352 reviews
Alaska Airlines
8.0
Very good
11,352 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.0

Food

7.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Nov 2025

LAX - LIH

The staff were exceptional! They all were kind, accommodating, and professional.
Delta
7.9
Good
7,998 reviews
Alaska Airlines
8.0
Very good
11,352 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.0

Food

7.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Nov 2025

LAX - LIH

The staff were exceptional! They all were kind, accommodating, and professional.
United Airlines
7.4
Good
9,046 reviews
Alaska Airlines
8.0
Very good
11,352 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.0

Food

7.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Nov 2025

LAX - LIH

The staff were exceptional! They all were kind, accommodating, and professional.
American Airlines
7.2
Good
11,038 reviews
Alaska Airlines
8.0
Very good
11,352 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.0

Food

7.1

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Nov 2025

LAX - LIH

The staff were exceptional! They all were kind, accommodating, and professional.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 6h 06m. Delta provides one of the quickest options available for as low as $304. Medford and Missouri are separated by a distance of 1712 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Kansas City or Medford - Columbia Regional, Medford - Lambert-St Louis is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to Missouri

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Top 4 airlines flying from Medford to Missouri

Discover the top 4 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$485FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$346FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$318Average$590FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$377Average$411FlexibilityNo cancel feeOn-time71%

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