HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$144+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:29 pm
MFR
-
MCI
1 stop8h 30m
Alaska Airlines
Thu 5/72:58 pm
MCI
-
MFR
1 stop6h 06m
Alaska Airlines
Deal found 2/2$262
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:00 am
MFR
-
MCI
1 stop5h 52m
United Airlines
Fri 5/86:00 am
MCI
-
MFR
2 stops7h 47m
United Airlines
Deal found 2/2$267
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:21 pm
MFR
-
MCI
1 stop9h 16m
Delta
Tue 5/197:00 am
MCI
-
MFR
1 stop7h 55m
Delta
Deal found 2/4$273
This deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:20 am
MFR
-
MCI
1 stop6h 38m
Delta
Tue 5/197:00 am
MCI
-
MFR
1 stop7h 55m
Delta
Deal found 2/2$287
This Alaska Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:32 pm
MFR
-
MCI
1 stop8h 04m
Alaska Airlines
Tue 9/155:00 pm
MCI
-
MFR
1 stop7h 55m
Alaska Airlines
Deal found 2/3$289
This Alaska Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/53:38 pm
MFR
-
MCI
1 stop22h 44m
Alaska Airlines
Sun 3/82:49 pm
MCI
-
MFR
1 stop11h 10m
Alaska Airlines
Deal found 2/4$297
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:55 am
MFR
-
MCI
2 stops10h 00m
Delta
Sun 3/82:40 pm
MCI
-
MFR
2 stops10h 09m
Delta
Deal found 2/4$298
This Alaska Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:50 pm
MFR
-
STL
1 stop26h 09m
Alaska Airlines
Tue 3/317:00 am
STL
-
MFR
1 stop14h 10m
Alaska Airlines
Deal found 2/3$426
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2711:13 am
MFR
-
STL
2 stops11h 08m
Delta
Tue 3/315:25 pm
STL
-
MFR
2 stops8h 22m
Delta
Deal found 2/3$469
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/75:00 am
MFR
-
STL
1 stop6h 16m
United Airlines
Tue 2/108:45 am
STL
-
MFR
1 stop6h 34m
United Airlines
Deal found 2/2$484
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:00 am
MFR
-
STL
2 stops8h 55m
United Airlines
Thu 2/129:55 am
STL
-
MFR
2 stops13h 23m
United Airlines
Deal found 2/1$514
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:02 am
MFR
-
JLN
2 stops10h 36m
United Airlines
Sat 2/286:19 pm
JLN
-
MFR
1 stop29h 03m
United Airlines
Deal found 2/3$562

Find flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$262
(Expedia)

One-way from

$144
(Delta)

Popular in

December

Cheapest in

August

Average price

$498
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
Search Deals
From Medford to Missouri
Search Deals
One-way flight from Medford to Missouri
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($228 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 4/28

1:29 pm-11:59 pm

1 stop8h 30m

Kansas City

Thu 5/7

2:58 pm-7:04 pm

1 stop6h 06m

$262

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 5/12

5:20 am-1:58 pm

1 stop6h 38m

Kansas City

Tue 5/19

7:00 am-12:55 pm

1 stop7h 55m

$262

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 4/28

5:00 am-12:52 pm

1 stop5h 52m

Kansas City

Thu 5/7

6:00 am-11:47 am

2 stops7h 47m

$267

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 4/28

5:00 am-12:52 pm

1 stop5h 52m

Kansas City

Fri 5/8

6:00 am-11:47 am

2 stops7h 47m

$267

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Mon 5/11

12:21 pm-11:37 pm

1 stop9h 16m

Kansas City

Tue 5/19

7:00 am-12:55 pm

1 stop7h 55m

$273

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sun 5/10

5:20 am-1:58 pm

1 stop6h 38m

Kansas City

Tue 5/19

7:00 am-12:55 pm

1 stop7h 55m

$287

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 3/5

6:55 am-6:55 pm

2 stops10h 00m

Kansas City

Sun 3/8

2:40 pm-10:49 pm

2 stops10h 09m

$298

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 3/27

7:50 pm-11:59 pm

1 stop26h 09m

Lambert-St Louis

Tue 3/31

7:00 am-7:10 pm

1 stop14h 10m

$426

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 3/27

11:13 am-12:21 am

2 stops11h 08m

Lambert-St Louis

Tue 3/31

5:25 pm-11:47 pm

2 stops8h 22m

$469

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 2/7

5:00 am-1:16 pm

1 stop6h 16m

Lambert-St Louis

Tue 2/10

4:15 pm-9:02 pm

1 stop6h 47m

$484

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 17 results
1
2

Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 4, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,839 reviews

Crew

8.5

Overall

8.0

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Alaska Airlines
8.0
Very good
11,839 reviews
Alaska Airlines
8.0
Very good
11,839 reviews

Crew

8.5

Overall

8.0

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Delta
7.9
Good
8,146 reviews
Alaska Airlines
8.0
Very good
11,839 reviews

Crew

8.5

Overall

8.0

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
United Airlines
7.4
Good
9,236 reviews
Alaska Airlines
8.0
Very good
11,839 reviews

Crew

8.5

Overall

8.0

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 5h 52m. Alaska Airlines provides one of the quickest options available for as low as $267. Medford and Missouri are separated by a distance of 1479 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Joplin, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Medford to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Las Vegas flights
Portland to Los Angeles flights
Portland to Sky Harbor Intl flights
Portland to Honolulu flights
Portland to San Francisco flights
Portland to John F Kennedy Intl flights
Portland to Ontario flights
Portland to Dallas/Fort Worth flights
Portland to Newark flights
Portland to Kahului flights
Portland to Denver flights
Portland to Palm Springs flights
Boise to Las Vegas flights
Portland to Orlando flights
Portland to Salt Lake City flights
Portland to LaGuardia flights
Portland to Hobby flights
Portland to Atlanta flights
Portland to San Diego flights
Portland to New Orleans flights
Portland to Boston flights
Portland to O'Hare Intl flights
Portland to Miami flights
Boise to Seattle flights
Portland to Santa Ana flights
Portland to George Bush Intcntl flights
Portland to Minneapolis flights
Portland to Dulles Intl flights
Boise to Dallas/Fort Worth flights
Portland to San Jose flights
Portland to Lihue flights
Portland to Austin flights
Boise to Denver flights
Portland to Reagan-National flights
Portland to Detroit flights
Boise to Los Angeles flights
Portland to Kailua-Kona flights
Boise to Sky Harbor Intl flights
Portland to Nashville flights
Portland to Oakland flights
Eugene to Las Vegas flights
Portland to Baltimore flights
Eugene to Denver flights
Portland to Tucson flights
Eugene to Sky Harbor Intl flights
Portland to Tampa flights
Boise to Orlando flights
Eugene to San Diego flights
Redmond to Sky Harbor Intl flights
Portland to Fort Lauderdale flights

Top 3 airlines flying from Medford to Missouri

Discover the top 3 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$168Average$455FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$390FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$308Average$571FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.