HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$276+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Feb 3 — Feb 101
Tue 2/3
Tue 2/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 4, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/59:21 pmMFR - MCI
1 stop24h 12mMultiple Airlines
Sun 2/87:00 amMCI - MFR
1 stop9h 42mMultiple Airlines
Deal found 1/4$276
This Alaska Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/171:41 pmMFR - MCI
1 stop22h 14mAlaska Airlines
Sun 2/222:49 pmMCI - MFR
1 stop28h 18mAlaska Airlines
Deal found 1/4$287
This Alaska Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:40 amMFR - MCI
1 stop6h 42mAlaska Airlines
Sun 2/222:49 pmMCI - MFR
1 stop11h 10mAlaska Airlines
Deal found 1/4$311
This Delta deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:05 amMFR - STL
2 stops12h 26mDelta
Wed 5/132:15 pmSTL - MFR
2 stops10h 58mDelta
Deal found 1/2$335
This Alaska Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:42 pmMFR - MCI
2 stops19h 23mAlaska Airlines
Sun 2/83:59 pmMCI - MFR
2 stops27h 03mAlaska Airlines
Deal found 1/4$345
This Delta deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:05 amMFR - STL
2 stops12h 26mDelta
Tue 5/125:30 pmSTL - MFR
2 stops8h 11mDelta
Deal found 1/2$348
This Alaska Airlines deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:07 amMFR - MCI
1 stop9h 09mAlaska Airlines
Tue 5/267:00 amMCI - MFR
1 stop7h 48mAlaska Airlines
Deal found 1/3$350
This Alaska Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:45 amMFR - STL
1 stop8h 05mAlaska Airlines
Sat 5/166:20 pmSTL - MFR
1 stop6h 33mAlaska Airlines
Deal found 1/2$351
This Alaska Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:45 amMFR - STL
1 stop8h 05mAlaska Airlines
Wed 5/136:20 pmSTL - MFR
1 stop6h 33mAlaska Airlines
Deal found 1/2$364
This Delta deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 amMFR - STL
2 stops9h 55mDelta
Sat 5/163:50 pmSTL - MFR
2 stops9h 23mDelta
Deal found 1/2$365
This Delta deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:05 amMFR - STL
2 stops9h 55mDelta
Wed 5/132:15 pmSTL - MFR
2 stops10h 58mDelta
Deal found 1/2$366
This Alaska Airlines deal was found by Cheapflights users on 1/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:45 amMFR - STL
1 stop8h 05mAlaska Airlines
Tue 5/127:00 amSTL - MFR
1 stop14h 04mAlaska Airlines
Deal found 1/2$367

Find flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated January 4, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$276
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$682
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
Search Deals
From Medford to Missouri
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($228 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 4, 2026.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 2/5

9:21 pm-11:33 pm

1 stop24h 12m

Kansas City

Sun 2/8

7:00 am-2:42 pm

1 stop9h 42m

$276

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 2/17

1:41 pm-1:55 pm

1 stop22h 14m

Kansas City

Sun 2/22

2:49 pm-5:07 pm

1 stop28h 18m

$287

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 2/20

7:40 am-4:22 pm

1 stop6h 42m

Kansas City

Sun 2/22

2:49 pm-11:59 pm

1 stop11h 10m

$311

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 5/12

6:05 am-6:00 pm

2 stops9h 55m

Lambert-St Louis

Wed 5/13

6:59 pm-11:41 pm

1 stop6h 42m

$342

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 2/5

5:42 pm-3:05 pm

2 stops19h 23m

Kansas City

Sun 2/8

3:59 pm-5:02 pm

2 stops27h 03m

$345

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 5/9

6:05 am-8:31 pm

2 stops12h 26m

Lambert-St Louis

Tue 5/12

5:30 pm-11:41 pm

2 stops8h 11m

$348

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 5/21

5:07 am-4:16 pm

1 stop9h 09m

Kansas City

Tue 5/26

7:00 am-12:48 pm

1 stop7h 48m

$350

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 5/12

5:45 am-3:50 pm

1 stop8h 05m

Lambert-St Louis

Wed 5/13

6:20 pm-10:53 pm

1 stop6h 33m

$351

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Wed 5/13

5:45 am-3:50 pm

1 stop8h 05m

Lambert-St Louis

Sat 5/16

6:20 pm-10:53 pm

1 stop6h 33m

$370

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sun 5/10

6:05 am-8:31 pm

2 stops12h 26m

Lambert-St Louis

Thu 5/14

2:18 pm-11:13 pm

2 stops10h 55m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/4

Showing 1-10 of 19 results
1
2

Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 4, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,633 reviews

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Alaska Airlines
8.0
Very good
11,633 reviews
Alaska Airlines
8.0
Very good
11,633 reviews

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Delta
7.9
Good
8,017 reviews
Alaska Airlines
8.0
Very good
11,633 reviews

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
United Airlines
7.4
Good
9,137 reviews
Alaska Airlines
8.0
Very good
11,633 reviews

Food

7.1

Crew

8.5

Entertainment

7.0

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 9h 55m. Alaska Airlines provides one of the quickest options available for as low as $342. Medford and Missouri are separated by a distance of 1712 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Columbia Regional, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Medford to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Las Vegas flights
Portland to Los Angeles flights
Portland to Atlanta flights
Portland to Honolulu flights
Portland to Sky Harbor Intl flights
Portland to San Francisco flights
Portland to Newark flights
Portland to John F Kennedy Intl flights
Portland to Miami flights
Portland to Kahului flights
Portland to Palm Springs flights
Portland to Orlando flights
Portland to Ontario flights
Portland to LaGuardia flights
Portland to Denver flights
Portland to San Diego flights
Portland to Hobby flights
Boise to Las Vegas flights
Portland to George Bush Intcntl flights
Portland to Minneapolis flights
Boise to Seattle flights
Portland to Santa Ana flights
Portland to New Orleans flights
Portland to Dallas/Fort Worth flights
Portland to Kailua-Kona flights
Portland to Boston flights
Portland to Lihue flights
Eugene to Atlanta flights
Portland to Salt Lake City flights
Eugene to Sky Harbor Intl flights
Portland to O'Hare Intl flights
Boise to Sky Harbor Intl flights
Portland to Austin flights
Boise to Denver flights
Portland to Nashville flights
Eugene to Las Vegas flights
Portland to Oakland flights
Portland to Tucson flights
Portland to Burbank flights
Boise to Los Angeles flights
Boise to O'Hare Intl flights
Boise to Dallas/Fort Worth flights
Portland to Tampa flights
Boise to Orlando flights
Portland to Seattle flights
Redmond to Seattle flights
Redmond to Sky Harbor Intl flights
Boise to Santa Ana flights
Portland to Reagan-National flights
Portland to Dulles Intl flights

Top 3 airlines flying from Medford to Missouri

Discover the top 3 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$476FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$390FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$308Average$577FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.