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$119+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Jan 31 — Feb 71
Sat 1/31
Sat 2/7
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Best flights from Medford to Missouri
Discover carefully curated flight deals from Medford to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 1, 2026.

This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:14 amMFR - STL
2 stops9h 58mDelta
Tue 4/282:22 pmSTL - MFR
2 stops10h 58mDelta
Deal found 12/30$303
This deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:45 amMFR - MCI
1 stop6h 19mAlaska Airlines
Sun 5/102:58 pmMCI - MFR
1 stop6h 06mAlaska Airlines
Deal found 12/29$350
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/175:00 amMFR - COU
2 stops10h 19mUnited Airlines
Wed 1/218:45 amCOU - MFR
1 stop6h 34mUnited Airlines
Deal found 12/29$355
This Alaska Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/285:35 pmMFR - STL
1 stop18h 19mAlaska Airlines
Sun 2/12:50 pmSTL - MFR
1 stop23h 53mAlaska Airlines
Deal found 12/31$357
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/186:00 amMFR - MCI
2 stops8h 08mUnited Airlines
Wed 1/2110:00 amMCI - MFR
2 stops13h 02mUnited Airlines
Deal found 12/29$403
This Alaska Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:41 pmMFR - MCI
1 stop26h 18mAlaska Airlines
Sun 5/107:00 amMCI - MFR
1 stop14h 04mAlaska Airlines
Deal found 12/29$372
This Alaska Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/185:42 amMFR - MCI
1 stop6h 01mAlaska Airlines
Wed 1/212:45 pmMCI - MFR
1 stop23h 58mAlaska Airlines
Deal found 12/29$377
This United Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1512:55 pmMFR - COU
1 stop5h 38mUnited Airlines
Mon 1/198:45 amCOU - MFR
1 stop6h 34mUnited Airlines
Deal found 12/31$421
This United Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1512:55 pmMFR - JLN
1 stop8h 35mUnited Airlines
Mon 1/198:52 amJLN - MFR
2 stops14h 10mUnited Airlines
Deal found 12/31$427
This Alaska Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:45 amMFR - STL
1 stop8h 05mAlaska Airlines
Tue 4/287:00 amSTL - MFR
1 stop11h 59mAlaska Airlines
Deal found 12/30$390
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/205:00 amMFR - COU
1 stop13h 33mUnited Airlines
Sat 1/248:45 amCOU - MFR
1 stop6h 34mUnited Airlines
Deal found 12/30$443
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/135:00 amMFR - JLN
2 stops10h 34mUnited Airlines
Sat 1/178:52 amJLN - MFR
2 stops14h 10mUnited Airlines
Deal found 12/28$459
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/1712:55 pmMFR - STL
1 stop6h 03mUnited Airlines
Wed 1/215:00 pmSTL - MFR
1 stop7h 59mUnited Airlines
Deal found 12/29$460

Find flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated January 1, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$303
(Delta)

One-way from

$119
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$546
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
Search Deals
From Medford to Missouri
Search Deals
One-way flight from Medford to Missouri
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($224 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 4/23

11:14 am-11:12 pm

2 stops9h 58m

Lambert-St Louis

Tue 4/28

2:22 pm-11:20 pm

2 stops10h 58m

$303

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 5/7

5:45 am-2:04 pm

1 stop6h 19m

Kansas City

Sun 5/10

2:58 pm-7:04 pm

1 stop6h 06m

$350

MedfordColumbia

MFR - COU

MFRCOU

Medford

Sat 1/17

5:00 am-5:19 pm

2 stops10h 19m

Columbia Regional

Wed 1/21

8:45 am-1:19 pm

1 stop6h 34m

$355

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Wed 1/28

5:35 pm-1:54 pm

1 stop18h 19m

Lambert-St Louis

Sun 2/1

2:50 pm-12:43 pm

1 stop23h 53m

$357

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 5/8

7:41 pm-11:59 pm

1 stop26h 18m

Kansas City

Sun 5/10

7:00 am-7:04 pm

1 stop14h 04m

$372

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sun 1/18

5:42 am-1:43 pm

1 stop6h 01m

Kansas City

Wed 1/21

2:45 pm-12:43 pm

1 stop23h 58m

$377

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 4/23

5:45 am-3:50 pm

1 stop8h 05m

Lambert-St Louis

Tue 4/28

7:00 am-4:59 pm

1 stop11h 59m

$390

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sun 1/18

6:00 am-4:08 pm

2 stops8h 08m

Kansas City

Wed 1/21

10:00 am-9:02 pm

2 stops13h 02m

$403

MedfordColumbia

MFR - COU

MFRCOU

Medford

Thu 1/15

12:55 pm-8:33 pm

1 stop5h 38m

Columbia Regional

Mon 1/19

8:45 am-1:19 pm

1 stop6h 34m

$421

MedfordJoplin

MFR - JLN

MFRJLN

Medford

Thu 1/15

12:55 pm-11:30 pm

1 stop8h 35m

Joplin

Mon 1/19

8:52 am-9:02 pm

2 stops14h 10m

$427

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/31

Showing 1-10 of 22 results
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Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 1, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,587 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Alaska Airlines
8.0
Very good
11,587 reviews
Alaska Airlines
8.0
Very good
11,587 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Delta
7.9
Good
8,012 reviews
Alaska Airlines
8.0
Very good
11,587 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
United Airlines
7.4
Good
9,124 reviews
Alaska Airlines
8.0
Very good
11,587 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Crew

8.5

Boarding

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 6h 19m. Delta provides one of the quickest options available for as low as $350. Medford and Missouri are separated by a distance of 1479 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Columbia Regional, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Medford to Missouri

Discover the top 3 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$476FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$346FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$318Average$584FlexibilityNo cancel feeOn-time69%

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