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$119+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:02 pm
MFR
-
MCI
1 stop7h 55m
American Airlines
Tue 3/32:24 pm
MCI
-
MFR
1 stop7h 14m
American Airlines
Deal found 1/27$237
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:02 am
MFR
-
MCI
1 stop5h 46m
United Airlines
Tue 3/310:24 am
MCI
-
MFR
2 stops12h 54m
United Airlines
Deal found 1/27$242
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:30 am
MFR
-
MCI
2 stops9h 59m
Delta
Tue 3/32:30 pm
MCI
-
MFR
2 stops10h 42m
Delta
Deal found 1/27$248
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:00 am
MFR
-
MCI
1 stop6h 38m
Delta
Sun 4/128:11 pm
MCI
-
MFR
1 stop5h 36m
Delta
Deal found 1/27$263
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:00 am
MFR
-
MCI
1 stop6h 38m
Delta
Sun 4/128:11 pm
MCI
-
MFR
1 stop5h 36m
Delta
Deal found 1/27$289
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:25 pm
MFR
-
MCI
1 stop8h 38m
Delta
Tue 5/197:00 am
MCI
-
MFR
2 stops11h 47m
Delta
Deal found 1/27$293
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:36 pm
MFR
-
MCI
2 stops12h 35m
United Airlines
Fri 5/86:00 am
MCI
-
MFR
2 stops7h 47m
United Airlines
Deal found 1/28$300
This Alaska Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:25 pm
MFR
-
STL
1 stop19h 41m
Alaska Airlines
Mon 5/257:56 pm
STL
-
MFR
1 stop18h 52m
Alaska Airlines
Deal found 1/27$334
This Alaska Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:36 pm
MFR
-
MCI
1 stop18h 28m
Alaska Airlines
Fri 5/85:11 pm
MCI
-
MFR
2 stops8h 48m
Alaska Airlines
Deal found 1/28$351
This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:44 pm
MFR
-
STL
1 stop18h 07m
Alaska Airlines
Fri 3/67:00 am
STL
-
MFR
1 stop8h 02m
Alaska Airlines
Deal found 1/28$354
This Alaska Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:25 pm
MFR
-
STL
1 stop8h 32m
Alaska Airlines
Sun 5/316:00 am
STL
-
MFR
1 stop8h 48m
Alaska Airlines
Deal found 1/27$359
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:30 am
MFR
-
STL
2 stops10h 55m
Delta
Fri 3/66:40 pm
STL
-
MFR
1 stop7h 16m
Delta
Deal found 1/28$390

Find flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$237
(American Airlines)

One-way from

$119
(Alaska Airlines)

Popular in

December

Cheapest in

August

Average price

$682
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
Search Deals
From Medford to Missouri
Search Deals
One-way flight from Medford to Missouri
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($228 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 2/24

2:02 pm-11:57 pm

1 stop7h 55m

Kansas City

Tue 3/3

2:24 pm-7:38 pm

1 stop7h 14m

$237

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 2/24

5:02 am-12:48 pm

1 stop5h 46m

Kansas City

Tue 3/3

10:24 am-9:18 pm

2 stops12h 54m

$242

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Tue 2/24

11:30 am-11:29 pm

2 stops9h 59m

Kansas City

Tue 3/3

2:30 pm-11:12 pm

2 stops10h 42m

$248

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sat 4/4

5:00 am-1:38 pm

1 stop6h 38m

Kansas City

Sun 4/12

8:11 pm-11:47 pm

1 stop5h 36m

$263

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sun 4/5

5:00 am-1:38 pm

1 stop6h 38m

Kansas City

Sun 4/12

8:11 pm-11:47 pm

1 stop5h 36m

$289

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Mon 5/11

12:25 pm-11:03 pm

1 stop8h 38m

Kansas City

Tue 5/19

7:00 am-4:47 pm

2 stops11h 47m

$293

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 5/1

5:36 pm-2:04 pm

1 stop18h 28m

Kansas City

Fri 5/8

5:11 pm-10:55 pm

1 stop7h 44m

$300

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 5/26

5:40 pm-3:50 pm

1 stop20h 10m

Lambert-St Louis

Sat 5/30

7:56 pm-12:48 pm

1 stop18h 52m

$334

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 5/22

7:25 pm-5:06 pm

1 stop19h 41m

Lambert-St Louis

Mon 5/25

7:56 pm-12:48 pm

1 stop18h 52m

$334

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 2/27

5:44 pm-1:51 pm

1 stop18h 07m

Lambert-St Louis

Fri 3/6

7:00 am-1:02 pm

1 stop8h 02m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 24 results
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Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,808 reviews

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Alaska Airlines
8.0
Very good
11,808 reviews
Alaska Airlines
8.0
Very good
11,808 reviews

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Delta
7.9
Good
8,127 reviews
Alaska Airlines
8.0
Very good
11,808 reviews

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
United Airlines
7.4
Good
9,215 reviews
Alaska Airlines
8.0
Very good
11,808 reviews

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 5h 46m. American Airlines provides one of the quickest options available for as low as $242. Medford and Missouri are separated by a distance of 1479 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Columbia Regional, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to Missouri

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Top 3 airlines flying from Medford to Missouri

Discover the top 3 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$168Average$455FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$390FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$308Average$571FlexibilityNo cancel feeOn-time69%

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