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$195+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:00 amMFR - STL
1 stop6h 23mDelta
Fri 12/267:20 amSTL - MFR
1 stop6h 35mDelta
Deal found 12/21$902
This Alaska Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:28 pmMFR - STL
1 stop6h 31mAlaska Airlines
Sat 12/277:00 amSTL - MFR
1 stop7h 48mAlaska Airlines
Deal found 12/21$904
This Alaska Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:07 amMFR - STL
2 stops15h 49mAlaska Airlines
Sun 12/288:00 amSTL - MFR
2 stops14h 26mAlaska Airlines
Deal found 12/22$924
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amMFR - STL
2 stops15h 43mUnited Airlines
Sat 12/278:15 amSTL - MFR
2 stops16h 42mUnited Airlines
Deal found 12/21$989
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:20 amMFR - STL
1 stop6h 36mAmerican Airlines
Sun 12/288:00 amSTL - MFR
1 stop7h 59mAmerican Airlines
Deal found 12/22$992

Find flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$236
(Alaska Airlines)

One-way from

$195
(Delta)

Popular in

December

Cheapest in

August

Average price

$973
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
Search Deals
From Medford to Missouri
Search Deals
One-way flight from Medford to Missouri
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($224 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 1/23

5:09 am-3:05 pm

1 stop7h 56m

Kansas City

Mon 1/26

3:59 pm-10:49 pm

1 stop8h 50m

$236

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 1/23

6:25 pm-10:32 am

2 stops14h 07m

Kansas City

Mon 1/26

5:10 pm-9:02 pm

1 stop5h 52m

$242

MedfordColumbia

MFR - COU

MFRCOU

Medford

Sat 1/17

5:00 am-5:19 pm

2 stops10h 19m

Columbia Regional

Wed 1/21

8:45 am-1:19 pm

1 stop6h 34m

$336

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 1/8

5:09 am-3:05 pm

1 stop7h 56m

Kansas City

Mon 1/12

3:59 pm-10:49 pm

1 stop8h 50m

$378

MedfordJoplin

MFR - JLN

MFRJLN

Medford

Thu 1/8

12:55 pm-11:30 pm

1 stop8h 35m

Joplin

Mon 1/12

8:52 am-9:02 pm

2 stops14h 10m

$429

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 1/8

6:00 am-8:33 pm

2 stops12h 33m

Kansas City

Mon 1/12

11:29 am-9:02 pm

2 stops11h 33m

$438

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 6/18

7:51 pm-4:06 pm

1 stop18h 15m

Kansas City

Thu 6/25

7:59 pm-9:29 am

1 stop15h 30m

$457

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

3:28 pm-11:59 pm

1 stop6h 31m

Lambert-St Louis

Sat 1/10

6:19 pm-11:56 pm

1 stop7h 37m

$490

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Sat 1/10

7:00 am-12:25 pm

1 stop7h 25m

$496

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 1/8

12:55 pm-8:58 pm

1 stop6h 03m

Lambert-St Louis

Mon 1/12

4:15 pm-9:02 pm

1 stop6h 47m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 14 results
1
2

Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 23, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,517 reviews

Entertainment

7.0

Crew

8.5

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.
Alaska Airlines
8.0
Very good
11,517 reviews
Alaska Airlines
8.0
Very good
11,517 reviews

Entertainment

7.0

Crew

8.5

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.
Delta
7.9
Good
8,015 reviews
Alaska Airlines
8.0
Very good
11,517 reviews

Entertainment

7.0

Crew

8.5

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.
United Airlines
7.4
Good
9,106 reviews
Alaska Airlines
8.0
Very good
11,517 reviews

Entertainment

7.0

Crew

8.5

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 7h 56m. Alaska Airlines provides one of the quickest options available for as low as $236. Medford and Missouri are separated by a distance of 1479 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Joplin, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Medford to Missouri

Discover the top 3 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$476FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$346FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$318Average$590FlexibilityNo cancel feeOn-time69%

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