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$244+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
nov. 28 — déc. 51
ven. 11/28
ven. 12/5
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated octobre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$245
(Kiwi.com)

One-way from

$244
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$540
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
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From Medford to Missouri
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One-way flight from Medford to Missouri
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High demand for flights, 6% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octobre 29, 2025.

This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 12/411:40 amMFR - STL
2 stops11h 08mDelta
dim. 12/72:20 pmSTL - MFR
2 stops10h 42mDelta
Deal found 10/27$294
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/2111:40 amMFR - STL
2 stops11h 06mDelta
dim. 11/236:40 amSTL - MFR
2 stops12h 03mDelta
Deal found 10/29$315
This KAYAK deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 12/45:45 amMFR - STL
1 stop6h 42mAlaska Airlines
dim. 12/77:00 amSTL - MFR
1 stop8h 16mAlaska Airlines
Deal found 10/27$330
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/211:45 pmMFR - STL
1 stop8h 06mAmerican Airlines
dim. 11/232:29 pmSTL - MFR
1 stop7h 06mAmerican Airlines
Deal found 10/27$350
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/116:00 amMFR - COU
2 stops12h 51mUnited Airlines
sam. 11/159:00 amCOU - MFR
1 stop6h 23mUnited Airlines
Deal found 10/27$358
This Alaska Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/213:35 pmMFR - STL
1 stop6h 19mAlaska Airlines
dim. 11/237:00 amSTL - MFR
1 stop19h 15mAlaska Airlines
Deal found 10/28$394
This Alaska Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/131:26 pmMFR - MCI
1 stop8h 20mAlaska Airlines
dim. 11/162:57 pmMCI - MFR
1 stop7h 10mAlaska Airlines
Deal found 10/27$445
This Alaska Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/131:26 pmMFR - MCI
1 stop8h 20mAlaska Airlines
lun. 11/177:00 amMCI - MFR
1 stop8h 58mAlaska Airlines
Deal found 10/29$464
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/136:00 amMFR - MCI
2 stops9h 21mDelta
lun. 11/176:16 pmMCI - MFR
1 stop7h 40mDelta
Deal found 10/29$470
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 12/251:36 pmMFR - STL
1 stop8h 23mAlaska Airlines
ven. 1/27:00 amSTL - MFR
1 stop9h 51mAlaska Airlines
Deal found 10/26$478
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/76:00 amMFR - MCI
2 stops9h 20mDelta
mar. 11/116:16 pmMCI - MFR
1 stop7h 40mDelta
Deal found 10/28$515
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/73:00 pmMFR - MCI
1 stop6h 38mAmerican Airlines
mar. 11/117:10 amMCI - MFR
1 stop8h 49mAmerican Airlines
Deal found 10/27$521

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octobre 29, 2025.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

dim. 1/11

9:21 pm-4:49 pm

1 stop17h 28m

Lambert-St Louis

mer. 1/14

7:43 pm-8:31 pm

2 stops26h 48m

$245

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

sam. 1/10

6:05 am-11:25 pm

2 stops15h 20m

Lambert-St Louis

mar. 1/13

11:23 am-11:19 pm

2 stops13h 56m

$274

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

jeu. 1/8

12:07 pm-11:25 pm

2 stops9h 18m

Lambert-St Louis

mer. 1/14

7:00 am-4:40 pm

2 stops11h 40m

$284

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

ven. 1/9

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

mer. 1/14

6:35 am-4:40 pm

2 stops12h 05m

$284

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

jeu. 12/4

11:40 am-12:48 am

2 stops11h 08m

Lambert-St Louis

dim. 12/7

2:20 pm-11:02 pm

2 stops10h 42m

$294

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

ven. 11/21

11:40 am-12:46 am

2 stops11h 06m

Lambert-St Louis

dim. 11/23

6:40 am-4:43 pm

2 stops12h 03m

$315

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

dim. 1/11

12:07 pm-11:25 pm

2 stops9h 18m

Lambert-St Louis

mer. 1/14

7:00 am-4:40 pm

2 stops11h 40m

$324

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

jeu. 12/4

5:45 am-2:27 pm

1 stop6h 42m

Lambert-St Louis

dim. 12/7

7:00 am-1:16 pm

1 stop8h 16m

$330

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

mar. 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

mar. 1/13

5:00 pm-10:57 pm

1 stop7h 57m

$331

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

mar. 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

mer. 1/14

5:00 pm-10:57 pm

1 stop7h 57m

$331

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 25 results
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2
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Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, April is the cheapest month in which you can book a flight from Medford to Missouri (average of $191). Flying from Medford to Missouri in December is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated octobre 29, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,211 reviews

Boarding

8.1

Crew

8.5

Comfort

7.8

Entertainment

7.0

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
Alaska Airlines
8.0
Very good
11,211 reviews
Alaska Airlines
8.0
Very good
11,211 reviews

Boarding

8.1

Crew

8.5

Comfort

7.8

Entertainment

7.0

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
Delta
7.9
Good
7,992 reviews
Alaska Airlines
8.0
Very good
11,211 reviews

Boarding

8.1

Crew

8.5

Comfort

7.8

Entertainment

7.0

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
United Airlines
7.4
Good
8,999 reviews
Alaska Airlines
8.0
Very good
11,211 reviews

Boarding

8.1

Crew

8.5

Comfort

7.8

Entertainment

7.0

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.
American Airlines
7.2
Good
11,032 reviews
Alaska Airlines
8.0
Very good
11,211 reviews

Boarding

8.1

Crew

8.5

Comfort

7.8

Entertainment

7.0

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 6h 01m. Delta provides one of the quickest options available for as low as $388. Medford and Missouri are separated by a distance of 1479 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Medford to Missouri one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $244. However, be on the lookout for offers from United Airlines and Alaska Airlines, as they are both options that can get you from Medford to Missouri for a low price.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Columbia Regional, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, April is the cheapest month in which you can book a flight from Medford to Missouri (average of $191). Flying from Medford to Missouri in December is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Medford to Missouri

Discover the top 4 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octobre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$492FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$386FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$318Average$594FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$377Average$411FlexibilityNo cancel feeOn-time71%

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