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$127+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated November 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$256
(Delta)

One-way from

$127
(Mytrip)

Popular in

November

Cheapest in

August

Average price

$772
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
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From Medford to Missouri
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One-way flight from Medford to Missouri
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Highest demand for flights based on searches. 16% potential increase in price ($105 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:50 pmMFR - COU
1 stop5h 39mUnited Airlines
Tue 12/98:00 amCOU - MFR
2 stops11h 52mUnited Airlines
Deal found 11/18$390
This Alaska Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:36 pmMFR - MCI
1 stop8h 37mAlaska Airlines
Tue 12/236:00 amMCI - MFR
1 stop19h 59mAlaska Airlines
Deal found 11/17$532
This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:00 amMFR - COU
1 stop13h 29mUnited Airlines
Thu 12/119:00 amCOU - MFR
1 stop6h 23mUnited Airlines
Deal found 11/17$588
This Delta deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:00 amMFR - STL
1 stop6h 31mDelta
Sun 11/236:34 amSTL - MFR
1 stop7h 27mDelta
Deal found 11/17$595
This Alaska Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2112:26 pmMFR - STL
2 stops17h 43mAlaska Airlines
Wed 11/261:20 pmSTL - MFR
2 stops11h 25mAlaska Airlines
Deal found 11/18$705
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:20 amMFR - STL
1 stop6h 20mAmerican Airlines
Wed 11/262:29 pmSTL - MFR
1 stop7h 06mAmerican Airlines
Deal found 11/18$736
This Orbitz deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:36 pmMFR - STL
1 stop8h 23mAlaska Airlines
Sun 12/287:00 amSTL - MFR
1 stop18h 59mAlaska Airlines
Deal found 11/18$763
This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:00 amMFR - STL
2 stops8h 46mUnited Airlines
Sun 11/239:00 amSTL - MFR
3 stops15h 30mUnited Airlines
Deal found 11/17$772
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:20 amMFR - MCI
2 stops14h 24mAmerican Airlines
Tue 12/239:44 amMCI - MFR
2 stops12h 36mAmerican Airlines
Deal found 11/17$1,349
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:20 amMFR - STL
2 stops12h 02mAmerican Airlines
Sun 12/289:36 amSTL - MFR
2 stops12h 44mAmerican Airlines
Deal found 11/18$1,495

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 2/21

6:05 am-9:38 pm

2 stops13h 33m

Lambert-St Louis

Wed 2/25

2:22 pm-4:40 pm

2 stops28h 18m

$256

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Sat 2/21

3:13 pm-11:42 pm

1 stop6h 29m

Kansas City

Tue 2/24

6:30 am-12:20 pm

1 stop7h 50m

$283

MedfordColumbia

MFR - COU

MFRCOU

Medford

Tue 1/13

6:00 am-9:05 pm

2 stops13h 05m

Columbia Regional

Tue 1/27

8:45 am-1:19 pm

1 stop6h 34m

$302

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 1/9

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Mon 1/12

7:00 am-12:25 pm

1 stop7h 25m

$308

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 2/21

5:45 am-1:51 pm

1 stop6h 06m

Lambert-St Louis

Wed 2/25

7:00 am-1:02 pm

1 stop8h 02m

$342

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 1/9

3:00 pm-11:59 pm

1 stop6h 59m

Lambert-St Louis

Mon 1/12

7:27 am-1:07 pm

1 stop7h 40m

$388

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 4/7

5:55 am-1:25 pm

1 stop5h 30m

Lambert-St Louis

Wed 4/8

6:59 pm-11:47 pm

1 stop6h 48m

$389

MedfordColumbia

MFR - COU

MFRCOU

Medford

Sat 12/6

12:50 pm-8:29 pm

1 stop5h 39m

Columbia Regional

Tue 12/9

8:00 am-5:52 pm

2 stops11h 52m

$390

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Wed 3/18

5:05 am-4:20 pm

1 stop9h 15m

Kansas City

Sun 3/22

2:55 pm-12:05 am

1 stop11h 10m

$401

MedfordJoplin

MFR - JLN

MFRJLN

Medford

Tue 3/3

5:02 am-5:38 pm

2 stops10h 36m

Joplin

Sat 3/7

8:54 am-9:33 pm

2 stops14h 39m

$510

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 21 results
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2
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Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 19, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,320 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
Alaska Airlines
8.0
Very good
11,320 reviews
Alaska Airlines
8.0
Very good
11,320 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
Delta
7.9
Good
8,004 reviews
Alaska Airlines
8.0
Very good
11,320 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
United Airlines
7.4
Good
9,025 reviews
Alaska Airlines
8.0
Very good
11,320 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.
American Airlines
7.2
Good
11,046 reviews
Alaska Airlines
8.0
Very good
11,320 reviews

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Marcie,Nov 2025

PIT - SEA

It was not a full flight, so I was able to enjoy a row to myself. Luck of the draw, I guess.

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 6h 06m. Delta provides one of the quickest options available for as low as $342. Medford and Missouri are separated by a distance of 1712 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Kansas City or Medford - Columbia Regional, Medford - Lambert-St Louis is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Medford to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Medford to Missouri

Discover the top 4 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$485FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$346FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$318Average$589FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$377Average$411FlexibilityNo cancel feeOn-time71%

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