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$220+ Cheap flights from Medford (MFR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Medford to Missouri

Keep the following information in mind while searching for Medford to Missouri flight deals. Data was last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(Delta)

One-way from

$220
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$682
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
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From Medford to Missouri
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One-way flight from Medford to Missouri
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Highest demand for flights based on searches. 27% potential increase in price ($228 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Medford to Missouri

Cheapest flights from Medford to Missouri
Explore the most affordable flight options available from Medford to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:05 pm
MFR
-
MCI
1 stop5h 34m
Delta
Sun 2/86:30 am
MCI
-
MFR
1 stop7h 55m
Delta
Deal found 1/13$289
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:00 am
MFR
-
MCI
3 stops13h 59m
United Airlines
Sun 2/85:10 pm
MCI
-
MFR
1 stop5h 52m
United Airlines
Deal found 1/13$325
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/285:00 am
MFR
-
MCI
1 stop5h 37m
United Airlines
Sun 2/15:10 pm
MCI
-
MFR
1 stop5h 52m
United Airlines
Deal found 1/13$339
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/305:00 am
MFR
-
MCI
1 stop5h 37m
United Airlines
Tue 2/311:29 am
MCI
-
MFR
2 stops11h 33m
United Airlines
Deal found 1/14$344
This Alaska Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/12:46 pm
MFR
-
STL
1 stop7h 13m
Alaska Airlines
Fri 3/67:00 am
STL
-
MFR
1 stop12h 07m
Alaska Airlines
Deal found 1/13$358
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/305:05 am
MFR
-
STL
1 stop6h 43m
Delta
Tue 2/36:40 am
STL
-
MFR
1 stop7h 45m
Delta
Deal found 1/15$359
This Delta deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/215:05 am
MFR
-
MCI
1 stop6h 53m
Delta
Tue 1/277:00 am
MCI
-
MFR
1 stop6h 18m
Delta
Deal found 1/14$374
This Expedia deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:51 pm
MFR
-
MCI
1 stop18h 15m
Alaska Airlines
Mon 6/227:59 pm
MCI
-
MFR
1 stop15h 30m
Alaska Airlines
Deal found 1/15$414
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1412:35 pm
MFR
-
COU
1 stop5h 49m
United Airlines
Sat 2/2111:15 am
COU
-
MFR
2 stops12h 03m
United Airlines
Deal found 1/14$424
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2712:55 pm
MFR
-
COU
1 stop5h 38m
United Airlines
Sat 1/3111:17 am
COU
-
MFR
2 stops11h 45m
United Airlines
Deal found 1/13$444
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2012:55 pm
MFR
-
JLN
1 stop8h 35m
United Airlines
Fri 1/308:52 am
JLN
-
MFR
2 stops14h 10m
United Airlines
Deal found 1/13$453
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/176:00 am
MFR
-
STL
1 stop7h 37m
United Airlines
Wed 1/212:45 pm
STL
-
MFR
1 stop8h 17m
United Airlines
Deal found 1/14$484

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Medford to Missouri that are best for you.

Fly from

Medford

Fly to

Missouri

Route

Depart

Return

Price

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 2/5

1:05 pm-8:39 pm

1 stop5h 34m

Kansas City

Sun 2/8

6:30 am-12:25 pm

1 stop7h 55m

$289

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 2/5

6:00 am-9:59 pm

3 stops13h 59m

Kansas City

Sun 2/8

5:10 pm-9:02 pm

1 stop5h 52m

$325

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Wed 1/28

5:00 am-12:37 pm

1 stop5h 37m

Kansas City

Sun 2/1

5:10 pm-9:02 pm

1 stop5h 52m

$339

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Fri 1/30

12:55 pm-8:33 pm

1 stop5h 38m

Kansas City

Tue 2/3

5:10 pm-9:02 pm

1 stop5h 52m

$339

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sun 3/1

2:46 pm-11:59 pm

1 stop7h 13m

Lambert-St Louis

Fri 3/6

7:00 am-5:07 pm

1 stop12h 07m

$358

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 1/30

5:05 am-1:48 pm

1 stop6h 43m

Lambert-St Louis

Tue 2/3

6:40 am-12:25 pm

1 stop7h 45m

$359

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Thu 6/18

7:51 pm-4:06 pm

1 stop18h 15m

Kansas City

Mon 6/22

7:59 pm-9:29 am

1 stop15h 30m

$414

MedfordColumbia

MFR - COU

MFRCOU

Medford

Sat 2/14

12:35 pm-8:24 pm

1 stop5h 49m

Columbia Regional

Sat 2/21

11:15 am-9:18 pm

2 stops12h 03m

$424

MedfordKansas City

MFR - MCI

MFRMCI

Medford

Mon 7/6

3:50 pm-4:06 pm

1 stop22h 16m

Kansas City

Fri 7/17

5:00 pm-10:59 pm

1 stop7h 59m

$439

MedfordColumbia

MFR - COU

MFRCOU

Medford

Tue 1/27

12:55 pm-8:33 pm

1 stop5h 38m

Columbia Regional

Sat 1/31

11:17 am-9:02 pm

2 stops11h 45m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 13 results
1
2

Best time to book a flight from Medford to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Missouri

What is the cheapest month to book a flight from Medford to Missouri?

Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 15, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,719 reviews

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Alaska Airlines
8.0
Very good
11,719 reviews
Alaska Airlines
8.0
Very good
11,719 reviews

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
Delta
7.9
Good
8,049 reviews
Alaska Airlines
8.0
Very good
11,719 reviews

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading
United Airlines
7.4
Good
9,164 reviews
Alaska Airlines
8.0
Very good
11,719 reviews

Food

7.1

Entertainment

7.0

Crew

8.5

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2026

STS - LAX

Enjoyed staff assistance from ticking thru tsa , boarding and in the plane Couldn’t pick a seat except upgrading

Related info for your journey

Find useful and relevant information for your journey from Medford to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to Missouri?

    Located just 3.0 mi from the city center, Medford (MFR) is the airport most travelers will use when flying to Missouri from Medford.

  • How long is the flight from Medford to Missouri?

    A quick flight from Medford to Missouri can take about 5h 34m. Delta provides one of the quickest options available for as low as $289. Medford and Missouri are separated by a distance of 1479 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Medford to Missouri?

    While some choose either Medford - Lambert-St Louis or Medford - Columbia Regional, Medford - Kansas City is the most popular route from Medford to Missouri.

  • Can I find deals for flights from Medford to Missouri that include hotel bookings?

    Yes. In addition to deals on Medford to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Missouri.

  • Can I find deals for business class flights from Medford to Missouri?

    Yes. Cheapflights offers flight deals from Medford to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Medford to Missouri (average of $178). Flying from Medford to Missouri in December is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Medford to Missouri

Discover the top 3 airlines that operate flights from Medford to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$168Average$454FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$256Average$390FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$308Average$580FlexibilityNo cancel feeOn-time69%

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