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Missouri

$377+ Cheap flights from Italy to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — STL
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from Italy to Missouri

Cheapest flights from Italy to Missouri
Explore the most affordable flight options available from Italy to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:25 am
MXP
-
MCI
2 stops20h 18m
American Airlines
Sun 2/221:58 pm
MCI
-
MXP
2 stops23h 02m
American Airlines
Deal found 2/4$727
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:20 am
BLQ
-
MCI
2 stops23h 38m
American Airlines
Mon 2/2311:02 am
MCI
-
BLQ
2 stops17h 38m
American Airlines
Deal found 2/3$732
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:25 am
MXP
-
MCI
2 stops19h 19m
American Airlines
Wed 3/119:28 am
MCI
-
MXP
2 stops16h 37m
American Airlines
Deal found 2/4$738
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:10 pm
FCO
-
MCI
1 stop16h 58m
American Airlines
Mon 2/2311:02 am
MCI
-
FCO
2 stops20h 53m
American Airlines
Deal found 2/3$743
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:50 am
LIN
-
MCI
2 stops19h 29m
American Airlines
Mon 9/287:49 pm
MCI
-
LIN
2 stops16h 06m
American Airlines
Deal found 2/3$745
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:35 am
LIN
-
MCI
2 stops18h 52m
American Airlines
Wed 2/254:16 pm
MCI
-
LIN
2 stops16h 29m
American Airlines
Deal found 2/3$754
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:25 am
MXP
-
MCI
2 stops19h 35m
American Airlines
Wed 2/259:42 am
MCI
-
MXP
2 stops15h 23m
American Airlines
Deal found 2/3$754
This Flighttix deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:10 pm
FCO
-
MCI
2 stops17h 33m
Iberia
Tue 3/105:51 am
MCI
-
FCO
1 stop21h 09m
Iberia
Deal found 2/3$758
This Iberia deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:30 am
FCO
-
MCI
2 stops22h 19m
Iberia
Tue 2/1712:38 pm
MCI
-
FCO
1 stop13h 22m
Iberia
Deal found 2/3$766
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:30 am
FLR
-
STL
1 stop13h 55m
United Airlines
Sun 9/131:27 pm
STL
-
FLR
2 stops20h 08m
United Airlines
Deal found 2/1$766
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:00 am
MXP
-
STL
2 stops16h 09m
United Airlines
Sun 9/276:49 pm
STL
-
MXP
1 stop11h 31m
United Airlines
Deal found 2/1$769
This Iberia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:55 am
LIN
-
MCI
2 stops22h 11m
Iberia
Sun 2/2211:02 am
MCI
-
LIN
2 stops16h 53m
Iberia
Deal found 2/2$770

Find flight deals from Italy to Missouri

Keep the following information in mind while searching for Italy to Missouri flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$727
(American Airlines)

One-way from

$377
(Kiwi.com)
Provider with most accurate pricing for Rome (ROM)-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rome (ROM)-Lambert-St Louis flights.
Search Deals
From Italy to Missouri
Search Deals
One-way flight from Italy to Missouri
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Italy to Missouri that are best for you.

Fly from

Italy

Fly to

Missouri

Route

Depart

Return

Price

MilanKansas City

MXP - MCI

MXPMCI

Milan Malpensa

Wed 2/18

10:25 am-11:43 pm

2 stops20h 18m

Kansas City

Sun 2/22

1:58 pm-8:00 pm

2 stops23h 02m

$727

BolognaKansas City

BLQ - MCI

BLQMCI

Bologna Guglielmo Marconi

Thu 2/19

7:20 am-11:58 pm

2 stops23h 38m

Kansas City

Mon 2/23

11:02 am-11:40 am

2 stops17h 38m

$732

RomeKansas City

FCO - MCI

FCOMCI

Rome Fiumicino

Thu 2/19

1:10 pm-11:08 pm

1 stop16h 58m

Kansas City

Mon 2/23

4:16 pm-7:35 pm

2 stops20h 19m

$744

MilanKansas City

LIN - MCI

LINMCI

Milan Linate

Wed 2/18

7:35 am-7:27 pm

2 stops18h 52m

Kansas City

Wed 2/25

4:16 pm-3:45 pm

2 stops16h 29m

$754

MilanKansas City

MXP - MCI

MXPMCI

Milan Malpensa

Wed 2/18

10:25 am-11:00 pm

2 stops19h 35m

Kansas City

Wed 2/25

9:42 am-8:05 am

2 stops15h 23m

$754

RomeKansas City

FCO - MCI

FCOMCI

Rome Fiumicino

Tue 3/3

1:10 pm-11:08 pm

1 stop16h 58m

Kansas City

Tue 3/10

5:51 am-9:00 am

1 stop21h 09m

$755

RomeKansas City

FCO - MCI

FCOMCI

Rome Fiumicino

Tue 3/3

1:10 pm-11:43 pm

2 stops17h 33m

Kansas City

Tue 3/10

11:14 am-9:00 am

2 stops15h 46m

$755

MilanKansas City

LIN - MCI

LINMCI

Milan Linate

Wed 2/18

7:55 am-11:06 pm

2 stops22h 11m

Kansas City

Sun 2/22

11:02 am-10:55 am

2 stops16h 53m

$770

RomeSt. Louis

FCO - STL

FCOSTL

Rome Fiumicino

Wed 2/18

7:00 am-11:59 pm

2 stops23h 59m

Lambert-St Louis

Sun 2/22

12:15 pm-8:30 am

1 stop13h 15m

$794

RomeSt. Louis

FCO - STL

FCOSTL

Rome Fiumicino

Wed 2/18

7:00 am-5:44 pm

2 stops17h 44m

Lambert-St Louis

Sun 2/22

8:17 am-7:55 am

2 stops16h 38m

$794

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 60 results
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Best time to book a flight from Italy to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to Missouri

What is the cheapest month to book a flight from Italy to Missouri?

Currently, March is the cheapest month in which you can book a flight from Italy to Missouri (average of $643). Flying from Italy to Missouri in June is currently the most expensive (average of $937). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 5, 2026.
See what other customers who have flown with American Airlines from Italy to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,237 reviews

Crew

8.0

Overall

7.2

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,237 reviews
American Airlines
7.2
Good
11,237 reviews

Crew

8.0

Overall

7.2

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Italy to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Italy to Missouri?

    For as low as $727, American Airlines can have you in Missouri from Italy in 20h 18m. The distance between Italy and Missouri is about 4897 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Italy to Missouri one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $76. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Italy to Missouri for a low price.

  • Can I find deals for flights from Italy to Missouri that include hotel bookings?

    Yes. In addition to deals on Italy to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to Missouri.

  • Can I find deals for business class flights from Italy to Missouri?

    Yes. Cheapflights offers flight deals from Italy to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Italy to Missouri?

    Currently, March is the cheapest month in which you can book a flight from Italy to Missouri (average of $643). Flying from Italy to Missouri in June is currently the most expensive (average of $937). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Italy to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Italy to Missouri

Discover the top airline that operate flights from Italy to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$643Average$795FlexibilityNo cancel feeOn-time71%

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