$405+ Cheap flights from Frankfurt (FRA) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — STL
Nov 29 — Dec 61
1 adult, Economy
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Cheapest flights from Frankfurt to MissouriExplore the most affordable flight options available from Frankfurt to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.
Explore the most affordable flight options available from Frankfurt to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.
This Ticket deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:50 amFRA - STL
2 stops15h 56mKLM
Sun 12/79:30 amSTL - FRA
1 stop16h 10mKLM
Deal found 10/29![KLM logo]()
$624
This Billigflug deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:50 amFRA - STL
1 stop14h 04mMultiple Airlines
Sun 12/711:34 amSTL - FRA
1 stop12h 41mMultiple Airlines
Deal found 10/28![Multiple Airlines logo]()
$634
This ResecentrumGruppen deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ResecentrumGruppen is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2310:45 amFRA - STL
Nonstop10h 10mLufthansa
Sun 12/71:00 pmSTL - FRA
1 stop10h 35mLufthansa
Deal found 10/28![Lufthansa logo]()
$636
This flygcity.se deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flygcity.se is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2310:15 amFRA - STL
1 stop16h 15mBritish Airways
Sun 12/711:50 amSTL - FRA
2 stops15h 40mBritish Airways
Deal found 10/28![British Airways logo]()
$637
This Travelis deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelis is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:45 amFRA - STL
Nonstop10h 10mLufthansa
Sun 12/71:00 pmSTL - FRA
1 stop13h 55mLufthansa
Deal found 10/29![Lufthansa logo]()
$640
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1610:50 amFRA - STL
1 stop15h 39mAmerican Airlines
Tue 12/23:43 pmSTL - FRA
2 stops20h 57mAmerican Airlines
Deal found 10/28![American Airlines logo]()
$641
This British Airways deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:50 amFRA - STL
1 stop14h 04mBritish Airways
Sun 12/711:50 amSTL - FRA
2 stops15h 40mBritish Airways
Deal found 10/28![British Airways logo]()
$643
This Billigflug deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:50 amFRA - MCI
2 stops17h 33mMultiple Airlines
Wed 11/199:45 amMCI - FRA
1 stop14h 30mMultiple Airlines
Deal found 10/29![Multiple Airlines logo]()
$693
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:15 amFRA - MCI
1 stop34h 51mAmerican Airlines
Mon 11/172:31 pmMCI - FRA
2 stops20h 39mAmerican Airlines
Deal found 10/28![American Airlines logo]()
$701
This Expedia deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:15 amFRA - MCI
1 stop19h 52mBritish Airways
Sat 3/146:13 pmMCI - FRA
2 stops18h 07mBritish Airways
Deal found 10/29![British Airways logo]()
$708
This Finnair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2210:50 amFRA - MCI
1 stop13h 56mMultiple Airlines
Tue 12/97:00 amMCI - FRA
2 stops18h 50mMultiple Airlines
Deal found 10/29![Multiple Airlines logo]()
$714
This Flysmarter deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:55 amFRA - MCI
2 stops16h 52mKLM
Wed 11/263:25 pmMCI - FRA
1 stop34h 15mKLM
Deal found 10/30![KLM logo]()
$715
Cheap flight deals from Frankfurt to Missouri
Keep the following information in mind while searching for Frankfurt to Missouri flight deals. Data was last updated October 30, 2025.
Round-trip from | $624 (Ticket) |
|---|---|
One-way from | $405 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $753 |
Cheapflights Fare Finder
Customize your flight search to find flights from Frankfurt to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Missouri that are best for you.
Fly from
Frankfurt
Fly to
Missouri
Route
Depart
Return
Price
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Wed 1/14
7:20 am-9:10 pm
2 stops20h 50m
Lambert-St Louis
Wed 3/4
2:00 pm-2:05 pm
2 stops17h 05m
$627
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Fri 11/21
10:50 am-5:54 pm
1 stop14h 04m
Lambert-St Louis
Sun 12/7
11:34 am-7:15 am
1 stop12h 41m
$634
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Thu 1/22
10:15 am-11:12 pm
1 stop19h 57m
Lambert-St Louis
Thu 1/29
3:37 pm-2:25 pm
2 stops15h 48m
$643
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Fri 11/21
10:50 am-5:54 pm
1 stop14h 04m
Lambert-St Louis
Sun 12/7
11:50 am-10:30 am
2 stops15h 40m
$643
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Sun 11/16
10:15 am-7:30 pm
1 stop16h 15m
Lambert-St Louis
Tue 12/2
2:05 pm-8:50 am
1 stop11h 45m
$654
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Wed 1/14
11:05 am-11:59 pm
1 stop19h 54m
Lambert-St Louis
Wed 3/4
3:50 pm-7:30 am
Nonstop8h 40m
$657
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Fri 11/21
7:00 am-10:34 pm
2 stops22h 34m
Lambert-St Louis
Sun 12/7
5:02 am-8:50 am
1 stop20h 48m
$661
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Wed 11/19
10:50 am-6:25 pm
1 stop14h 35m
Lambert-St Louis
Wed 11/26
7:11 am-8:50 am
1 stop18h 39m
$663
Frankfurt am MainSt. Louis
FRA - STL
FRASTL
Frankfurt am Main
Wed 11/19
6:55 am-4:07 pm
2 stops16h 12m
Lambert-St Louis
Wed 11/26
6:00 am-7:50 am
2 stops18h 50m
$669
Frankfurt am MainSpringfield
FRA - SGF
FRASGF
Frankfurt am Main
Fri 2/27
10:50 am-10:30 pm
2 stops18h 40m
Springfield-Branson
Mon 3/2
6:21 pm-6:10 pm
2 stops16h 49m
$701
Showing 1-10 of 39 results
Best time to book a flight from Frankfurt to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Frankfurt am Main Airport to Missouri
What is the cheapest month to book a flight from Frankfurt am Main Airport to Missouri?
Currently, May is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Missouri (average of $481). Flying from Frankfurt am Main Airport to Missouri in December is currently the most expensive (average of $621). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from FRA to MO?
Find hourly flight availability from Frankfurt to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.
It’s typically best to fly out from Frankfurt am Main Airport to Missouri in the afternoon. Doing so could potentially save you 28% on the flight price compared to flying in the evening, which is usually more expensive.
How much does it cost to fly round-trip from Frankfurt am Main Airport to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with United Airlines, American Airlines, and Lufthansa from Frankfurt am Main Airport to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Overall
7.4
Entertainment
7.1
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Related info for your journey
Find useful and relevant information for your journey from Frankfurt to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Frankfurt to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 3 airlines flying from Frankfurt to Missouri
Discover the top 3 airlines that operate flights from Frankfurt to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$589 | Average$952 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$592 | Average$851 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$592 | Average$761 | FlexibilityNo cancel fee | On-time69% |