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$424+ Cheap flights from Frankfurt (FRA) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — STL
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Frankfurt to Missouri

Cheapest flights from Frankfurt to Missouri
Explore the most affordable flight options available from Frankfurt to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Flighttix deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:40 amFRA - STL
1 stop14h 47mLufthansa
Fri 1/911:22 amSTL - FRA
1 stop14h 48mLufthansa
Deal found 12/22$789
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:50 pmFRA - STL
2 stops27h 59mUnited Airlines
Fri 1/91:15 pmSTL - FRA
2 stops15h 35mUnited Airlines
Deal found 12/22$822
This lastminute.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:50 amFRA - MCI
1 stop16h 51mVirgin Atlantic
Mon 12/2910:41 amMCI - FRA
1 stop14h 09mVirgin Atlantic
Deal found 12/21$1,015
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:50 amFRA - MCI
1 stop31h 36mAmerican Airlines
Mon 12/2912:16 pmMCI - FRA
2 stops26h 39mAmerican Airlines
Deal found 12/21$1,025
This Iberia deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:15 amFRA - MCI
1 stop18h 29mMultiple Airlines
Fri 2/272:02 pmMCI - FRA
2 stops18h 38mMultiple Airlines
Deal found 12/23$1,026
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:15 pmFRA - MCI
2 stops28h 28mDelta
Thu 1/110:42 amMCI - FRA
2 stops17h 33mDelta
Deal found 12/21$1,034
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:15 amFRA - MCI
2 stops20h 33mAmerican Airlines
Mon 12/2912:16 pmMCI - FRA
2 stops26h 39mAmerican Airlines
Deal found 12/21$1,037
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:00 amFRA - MCI
2 stops18h 31mUnited Airlines
Thu 1/17:40 amMCI - FRA
2 stops16h 30mUnited Airlines
Deal found 12/21$1,038
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:50 amFRA - MCI
2 stops39h 01mAmerican Airlines
Mon 12/296:00 amMCI - FRA
1 stop18h 15mAmerican Airlines
Deal found 12/21$1,039
This Delta deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:15 amFRA - MCI
2 stops20h 41mDelta
Fri 2/275:35 amMCI - FRA
2 stops19h 15mDelta
Deal found 12/23$1,041
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:50 amFRA - MCI
2 stops36h 07mDelta
Thu 1/16:00 amMCI - FRA
2 stops22h 15mDelta
Deal found 12/21$1,046
This KLM deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:40 amFRA - MCI
1 stop13h 17mKLM
Mon 12/293:35 pmMCI - FRA
1 stop34h 05mKLM
Deal found 12/21$1,076

Find flight deals from Frankfurt to Missouri

Keep the following information in mind while searching for Frankfurt to Missouri flight deals. Data was last updated December 23, 2025.

Round-trip from

$620
(Billigflug)

One-way from

$424
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$966
From Frankfurt am Main to Missouri
Search Deals
One-way flight from Frankfurt am Main to Missouri
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Frankfurt to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Missouri that are best for you.

Fly from

Frankfurt

Fly to

Missouri

Route

Depart

Return

Price

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Thu 1/15

10:15 am-9:15 pm

2 stops18h 00m

Lambert-St Louis

Wed 3/25

11:47 am-7:15 am

1 stop13h 28m

$620

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 2/6

10:15 am-6:34 pm

1 stop15h 19m

Lambert-St Louis

Fri 2/13

5:14 am-7:15 am

1 stop19h 01m

$622

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Thu 1/22

10:15 am-6:34 pm

1 stop15h 19m

Lambert-St Louis

Mon 1/26

3:37 pm-6:10 pm

2 stops19h 33m

$627

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 4/10

9:20 am-5:13 pm

1 stop14h 53m

Lambert-St Louis

Sun 4/26

6:29 pm-10:25 pm

2 stops20h 56m

$629

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Wed 2/4

10:15 am-6:34 pm

1 stop15h 19m

Lambert-St Louis

Wed 2/11

3:54 pm-2:05 pm

2 stops15h 11m

$630

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Wed 3/4

10:15 am-7:25 pm

1 stop16h 10m

Lambert-St Louis

Sun 3/8

2:00 pm-2:05 pm

2 stops18h 05m

$630

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 1/16

7:00 am-6:34 pm

2 stops18h 34m

Lambert-St Louis

Fri 1/30

6:44 pm-3:40 pm

2 stops13h 56m

$631

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 1/16

10:15 am-11:12 pm

1 stop19h 57m

Lambert-St Louis

Fri 1/30

10:17 am-7:15 am

1 stop13h 58m

$633

Frankfurt am MainKansas City

FRA - MCI

FRAMCI

Frankfurt am Main

Thu 2/5

10:15 am-11:51 pm

2 stops20h 36m

Kansas City

Sun 2/15

5:47 pm-4:45 pm

2 stops15h 58m

$693

Frankfurt am MainKansas City

FRA - MCI

FRAMCI

Frankfurt am Main

Thu 1/29

6:55 am-9:03 pm

2 stops21h 08m

Kansas City

Thu 2/5

2:12 pm-11:15 am

2 stops14h 03m

$693

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 32 results
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Best time to book a flight from Frankfurt to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Missouri

What is the cheapest month to book a flight from Frankfurt am Main Airport to Missouri?

Currently, May is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Missouri (average of $481). Flying from Frankfurt am Main Airport to Missouri in December is currently the most expensive (average of $659). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FRA to MO?

Find hourly flight availability from Frankfurt to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

It’s typically best to fly out from Frankfurt am Main Airport to Missouri in the afternoon. Doing so could potentially save you 28% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 23, 2025.
Peruse reviews from past customers who have flown with United Airlines, American Airlines, and Lufthansa from Frankfurt am Main Airport to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,106 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,106 reviews
United Airlines
7.4
Good
9,106 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,050 reviews
United Airlines
7.4
Good
9,106 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
Lufthansa
6.8
Okay
7,649 reviews
United Airlines
7.4
Good
9,106 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Frankfurt am Main Airport to Missouri?

    American Airlines, Delta, and KLM can get you from Frankfurt am Main Airport to Missouri in just under 15h 19m. Your travel time can differ by up to 5h 17m. The distance between Frankfurt am Main Airport and Missouri is about 4577 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Frankfurt am Main Airport to Missouri?

    When deciding which route to take from Frankfurt am Main Airport to Missouri consider Frankfurt am Main - Lambert-St Louis, Frankfurt am Main - Kansas City or Frankfurt am Main - Springfield-Branson as they are the most popular.

  • Can I find deals for flights from Frankfurt to Missouri that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Missouri.

  • Can I find deals for business class flights from Frankfurt to Missouri?

    Yes. Cheapflights offers flight deals from Frankfurt to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Missouri?

    Currently, May is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Missouri (average of $481). Flying from Frankfurt am Main Airport to Missouri in December is currently the most expensive (average of $659). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Frankfurt to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Frankfurt to Missouri

Discover the top 3 airlines that operate flights from Frankfurt to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$592Average$851FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$592Average$764FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$618Average$955FlexibilityNo cancel feeOn-time76%

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