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$412+ Cheap flights from Frankfurt (FRA) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — STL
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Frankfurt to Missouri

Keep the following information in mind while searching for Frankfurt to Missouri flight deals. Data was last updated September 16, 2025.

Round-trip from

$585
(Travelis)

One-way from

$412
(Billigflug)

Popular in

July

Cheapest in

March

Average price

$811

Good one-way deal

$1,006 or less
From Frankfurt am Main to Missouri
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One-way flight from Frankfurt am Main to Missouri
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Highest demand for flights based on searches. 9% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a one-way flight from Frankfurt am Main to Missouri.
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Find flight deals from Frankfurt to Missouri

Cheapest flights from Frankfurt to Missouri
Explore the most affordable flight options available from Frankfurt to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Billigflug deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:50 amFRA - STL
1 stop13h 56mMultiple Airlines
Fri 11/144:42 pmSTL - FRA
2 stops15h 58mMultiple Airlines
Deal found 9/14$585
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:00 amFRA - STL
2 stops17h 29mDelta
Mon 10/2011:21 amSTL - FRA
2 stops14h 39mDelta
Deal found 9/15$588
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:00 amFRA - STL
2 stops16h 37mDelta
Sat 10/116:00 amSTL - FRA
1 stop19h 55mDelta
Deal found 9/15$592
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:15 pmFRA - STL
2 stops25h 00mKLM
Fri 11/144:30 pmSTL - FRA
2 stops14h 10mKLM
Deal found 9/14$594
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:50 amFRA - STL
1 stop14h 12mAir France
Fri 11/142:36 pmSTL - FRA
2 stops19h 09mAir France
Deal found 9/14$596
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:50 amFRA - STL
1 stop14h 12mDelta
Fri 11/146:09 pmSTL - FRA
2 stops15h 36mDelta
Deal found 9/15$597
This KLM deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:00 amFRA - STL
2 stops14h 32mKLM
Fri 10/3110:30 amSTL - FRA
1 stop16h 10mKLM
Deal found 9/16$598
This Billigflug deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2210:55 amFRA - STL
1 stop16h 58mMultiple Airlines
Fri 10/3110:10 amSTL - FRA
1 stop15h 05mMultiple Airlines
Deal found 9/16$599
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/611:45 amFRA - STL
2 stops18h 56mDelta
Sat 10/181:30 pmSTL - FRA
2 stops17h 05mDelta
Deal found 9/14$600
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/219:50 amFRA - STL
1 stop15h 07mDelta
Wed 12/32:36 pmSTL - FRA
2 stops16h 04mDelta
Deal found 9/16$603
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:55 amFRA - MCI
2 stops15h 58mDelta
Tue 12/26:38 pmMCI - FRA
2 stops15h 07mDelta
Deal found 9/14$640
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:00 amFRA - MCI
2 stops16h 21mDelta
Sat 10/410:33 amMCI - FRA
1 stop16h 17mDelta
Deal found 9/15$644

Cheapflights Fare Finder

 
Customize your flight search to find flights from Frankfurt to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Missouri that are best for you.

Fly from

Frankfurt

Fly to

Missouri

Route

Depart

Return

Price

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 10/31

10:50 am-3:45 pm

1 stop34h 55m

Lambert-St Louis

Fri 11/14

4:42 pm-3:40 pm

2 stops15h 58m

$585

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Mon 10/13

7:00 am-5:29 pm

2 stops17h 29m

Lambert-St Louis

Mon 10/20

11:21 am-9:00 am

2 stops14h 39m

$588

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Tue 11/11

6:55 am-8:46 pm

2 stops20h 51m

Lambert-St Louis

Tue 12/2

6:06 pm-4:45 pm

2 stops15h 39m

$588

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Sat 11/1

6:55 am-4:43 pm

2 stops15h 48m

Lambert-St Louis

Sat 11/8

10:30 am-11:15 am

2 stops17h 45m

$588

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Thu 11/13

10:15 am-11:40 pm

2 stops20h 25m

Lambert-St Louis

Thu 12/4

6:06 pm-4:45 pm

2 stops15h 39m

$588

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 11/7

6:55 am-4:43 pm

2 stops16h 48m

Lambert-St Louis

Sun 11/16

7:02 pm-8:40 am

1 stop30h 38m

$592

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Mon 11/24

6:55 am-4:07 pm

2 stops16h 12m

Lambert-St Louis

Sat 12/6

5:12 pm-8:40 am

1 stop32h 28m

$592

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Sat 11/1

6:55 am-4:43 pm

2 stops15h 48m

Lambert-St Louis

Sat 11/8

10:30 am-8:40 am

1 stop15h 10m

$592

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Sun 10/12

10:15 am-9:38 pm

2 stops18h 23m

Lambert-St Louis

Sun 10/19

10:45 am-9:50 am

1 stop16h 05m

$592

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Tue 3/10

10:15 am-11:40 pm

2 stops19h 25m

Lambert-St Louis

Tue 4/14

1:30 pm-8:55 am

1 stop12h 25m

$592

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 35 results
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Best time to book a flight from Frankfurt to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Missouri

What is the cheapest month to book a flight from Frankfurt am Main Airport to Missouri?

Currently, August is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Missouri (average of $311). Flying from Frankfurt am Main Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FRA to MO?

Find hourly flight availability from Frankfurt to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Frankfurt am Main Airport to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 16, 2025.
Peruse reviews from past customers who have flown with United Airlines, American Airlines, and Lufthansa from Frankfurt am Main Airport to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,924 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
8,924 reviews
United Airlines
7.4
Good
8,924 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,924 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Lufthansa
6.8
Okay
7,407 reviews
United Airlines
7.4
Good
8,924 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Frankfurt am Main Airport to Missouri?

    Delta and American Airlines can get you from Frankfurt am Main Airport to Missouri in just under 17h. Your travel time can differ by up to 29m. The distance between Frankfurt am Main Airport and Missouri is about 4765 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Frankfurt am Main Airport to Missouri one-way?

    For one-way options, check prices for Finnair. According to our data, you can fly for as low as $420. Users have also found prices from $576 and $614 on British Airways and Aer Lingus, respectively.

  • What are the most popular routes from Frankfurt am Main Airport to Missouri?

    When deciding which route to take from Frankfurt am Main Airport to Missouri consider Frankfurt am Main - Lambert-St Louis, Frankfurt am Main - Kansas City or Frankfurt am Main - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Frankfurt am Main Airport to Missouri?

    On average you can expect to pay $1,027 for a flight from Frankfurt am Main Airport to Missouri. The cheapest flight overall is $633 while the most popular route, (Frankfurt am Main - Lambert-St Louis) is currently priced at $585.

  • Can I find deals for flights from Frankfurt to Missouri that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Missouri.

  • Can I find deals for business class flights from Frankfurt to Missouri?

    Yes. Cheapflights offers flight deals from Frankfurt to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Missouri (average of $311). Flying from Frankfurt am Main Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Frankfurt to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Frankfurt to Missouri

Discover the top 3 airlines that operate flights from Frankfurt to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$557Average$732FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$589Average$937FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$592Average$759FlexibilityNo cancel feeOn-time69%

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