Missouri

$405+ Cheap flights from Frankfurt (FRA) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — STL
Nov 29 — Dec 61
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Find flight deals from Frankfurt to Missouri

Cheapest flights from Frankfurt to Missouri
Explore the most affordable flight options available from Frankfurt to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Ticket deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:50 amFRA - STL
2 stops15h 56mKLM
Sun 12/79:30 amSTL - FRA
1 stop16h 10mKLM
Deal found 10/29$624
This Billigflug deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:50 amFRA - STL
1 stop14h 04mMultiple Airlines
Sun 12/711:34 amSTL - FRA
1 stop12h 41mMultiple Airlines
Deal found 10/28$634
This ResecentrumGruppen deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ResecentrumGruppen is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2310:45 amFRA - STL
Nonstop10h 10mLufthansa
Sun 12/71:00 pmSTL - FRA
1 stop10h 35mLufthansa
Deal found 10/28$636
This flygcity.se deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flygcity.se is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2310:15 amFRA - STL
1 stop16h 15mBritish Airways
Sun 12/711:50 amSTL - FRA
2 stops15h 40mBritish Airways
Deal found 10/28$637
This Travelis deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelis is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:45 amFRA - STL
Nonstop10h 10mLufthansa
Sun 12/71:00 pmSTL - FRA
1 stop13h 55mLufthansa
Deal found 10/29$640
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1610:50 amFRA - STL
1 stop15h 39mAmerican Airlines
Tue 12/23:43 pmSTL - FRA
2 stops20h 57mAmerican Airlines
Deal found 10/28$641
This British Airways deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:50 amFRA - STL
1 stop14h 04mBritish Airways
Sun 12/711:50 amSTL - FRA
2 stops15h 40mBritish Airways
Deal found 10/28$643
This Billigflug deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:50 amFRA - MCI
2 stops17h 33mMultiple Airlines
Wed 11/199:45 amMCI - FRA
1 stop14h 30mMultiple Airlines
Deal found 10/29$693
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:15 amFRA - MCI
1 stop34h 51mAmerican Airlines
Mon 11/172:31 pmMCI - FRA
2 stops20h 39mAmerican Airlines
Deal found 10/28$701
This Expedia deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:15 amFRA - MCI
1 stop19h 52mBritish Airways
Sat 3/146:13 pmMCI - FRA
2 stops18h 07mBritish Airways
Deal found 10/29$708
This Finnair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2210:50 amFRA - MCI
1 stop13h 56mMultiple Airlines
Tue 12/97:00 amMCI - FRA
2 stops18h 50mMultiple Airlines
Deal found 10/29$714
This Flysmarter deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:55 amFRA - MCI
2 stops16h 52mKLM
Wed 11/263:25 pmMCI - FRA
1 stop34h 15mKLM
Deal found 10/30$715

Cheap flight deals from Frankfurt to Missouri

Keep the following information in mind while searching for Frankfurt to Missouri flight deals. Data was last updated October 30, 2025.

Round-trip from

$624
(Ticket)

One-way from

$405
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$753
From Frankfurt am Main to Missouri
One-way flight from Frankfurt am Main to Missouri
Highest demand for flights based on searches. 4% potential increase in price ($32 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in October 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Frankfurt to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Missouri that are best for you.

Fly from

Frankfurt

Fly to

Missouri

Route

Depart

Return

Price

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Wed 1/14

7:20 am-9:10 pm

2 stops20h 50m

Lambert-St Louis

Wed 3/4

2:00 pm-2:05 pm

2 stops17h 05m

$627

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 11/21

10:50 am-5:54 pm

1 stop14h 04m

Lambert-St Louis

Sun 12/7

11:34 am-7:15 am

1 stop12h 41m

$634

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Thu 1/22

10:15 am-11:12 pm

1 stop19h 57m

Lambert-St Louis

Thu 1/29

3:37 pm-2:25 pm

2 stops15h 48m

$643

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 11/21

10:50 am-5:54 pm

1 stop14h 04m

Lambert-St Louis

Sun 12/7

11:50 am-10:30 am

2 stops15h 40m

$643

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Sun 11/16

10:15 am-7:30 pm

1 stop16h 15m

Lambert-St Louis

Tue 12/2

2:05 pm-8:50 am

1 stop11h 45m

$654

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Wed 1/14

11:05 am-11:59 pm

1 stop19h 54m

Lambert-St Louis

Wed 3/4

3:50 pm-7:30 am

Nonstop8h 40m

$657

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Fri 11/21

7:00 am-10:34 pm

2 stops22h 34m

Lambert-St Louis

Sun 12/7

5:02 am-8:50 am

1 stop20h 48m

$661

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Wed 11/19

10:50 am-6:25 pm

1 stop14h 35m

Lambert-St Louis

Wed 11/26

7:11 am-8:50 am

1 stop18h 39m

$663

Frankfurt am MainSt. Louis

FRA - STL

FRASTL

Frankfurt am Main

Wed 11/19

6:55 am-4:07 pm

2 stops16h 12m

Lambert-St Louis

Wed 11/26

6:00 am-7:50 am

2 stops18h 50m

$669

Frankfurt am MainSpringfield

FRA - SGF

FRASGF

Frankfurt am Main

Fri 2/27

10:50 am-10:30 pm

2 stops18h 40m

Springfield-Branson

Mon 3/2

6:21 pm-6:10 pm

2 stops16h 49m

$701

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 39 results
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Best time to book a flight from Frankfurt to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Missouri

What is the cheapest month to book a flight from Frankfurt am Main Airport to Missouri?

Currently, May is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Missouri (average of $481). Flying from Frankfurt am Main Airport to Missouri in December is currently the most expensive (average of $621). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FRA to MO?

Find hourly flight availability from Frankfurt to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s typically best to fly out from Frankfurt am Main Airport to Missouri in the afternoon. Doing so could potentially save you 28% on the flight price compared to flying in the evening, which is usually more expensive.

How much does it cost to fly round-trip from Frankfurt am Main Airport to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with United Airlines, American Airlines, and Lufthansa from Frankfurt am Main Airport to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Overall

7.4

Entertainment

7.1

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Frankfurt am Main Airport to Missouri?

    British Airways, American Airlines, and KLM can get you from Frankfurt am Main Airport to Missouri in just under 18h 23m. Your travel time can differ by up to 1h 34m. The distance between Frankfurt am Main Airport and Missouri is about 4765 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Frankfurt am Main Airport to Missouri?

  • Can I find deals for flights from Frankfurt to Missouri that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Missouri.

  • Can I find deals for business class flights from Frankfurt to Missouri?

    Yes. Cheapflights offers flight deals from Frankfurt to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Missouri?

    Currently, May is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Missouri (average of $481). Flying from Frankfurt am Main Airport to Missouri in December is currently the most expensive (average of $621). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Frankfurt to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Frankfurt to Missouri

Discover the top 3 airlines that operate flights from Frankfurt to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$589Average$952FlexibilityNo cancel feeOn-time76%
American AirlinesCheapest$592Average$851FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$592Average$761FlexibilityNo cancel feeOn-time69%

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