In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What is the cheapest time of day to fly from KDT to MO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Cape Cod and the Islands to Missouri as you normally would.

How can I find direct flights from Cape Cod and the Islands to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Cod and the Islands to Missouri.

Can I find deals for business class flights from Cape Cod and the Islands to Missouri?

Yes. Cheapflights offers flight deals from Cape Cod and the Islands to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$322+ Flights from Cape Cod and the Islands to Missouri

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Cheap flight deals from Cape Cod and the Islands to Missouri

One-way

One-way flights from Cape Cod and the Islands to Missouri
Search for one-way flight options from Cape Cod and the Islands to Missouri. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.

Fri 6/54:02 pm

MVY

STL

1 stop5h 22m

Delta

Deal found 2/5

$322

Sun 7/2612:15 pm

MVY

STL

2 stops9h 16m

Delta

Deal found 2/4

$830

Find flight deals from Cape Cod and the Islands to Missouri

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Popular in	April
Cheapest in	August
Average price	$434

Provider with most accurate pricing for Boston Logan Intl-Lambert-St Louis flight deals.

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Highest demand for flights based on searches. 5% potential increase in price ($28 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in February 2026

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Use the filters below to find and compare flights from Cape Cod and the Islands to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

West TisburySt. Louis

MVY - STL

MVYSTL

West Tisbury Martha's Vineyard

Fri 6/5

4:02 pm-8:24 pm

1 stop5h 22m

$322

West TisburySt. Louis

MVY - STL

MVYSTL

West Tisbury Martha's Vineyard

Sun 7/26

12:15 pm-8:31 pm

2 stops9h 16m

$830

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/5

Best time to book a flight from Cape Cod and the Islands to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Cape Cod and the Islands with our price prediction graph.

MVY-STL

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

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Everything you need to know about your flight from Cape Cod and the Islands to Missouri

zzKDT-USMO

MVY-STL

No data available for this route at this time. Please check back soon.

Related info for your journey

Can I find deals for flights from Cape Cod and the Islands to Missouri that include hotel bookings?
Yes. In addition to deals on Cape Cod and the Islands to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Cape Cod and the Islands to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Cod and the Islands to Missouri.
Can I find deals for business class flights from Cape Cod and the Islands to Missouri?
Yes. Cheapflights offers flight deals from Cape Cod and the Islands to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$322+ Cheap flights from Cape Cod and the Islands to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Cape Cod and the Islands to Missouri with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Cape Cod and the Islands to Missouri

One-way flights from Cape Cod and the Islands to MissouriSearch for one-way flight options from Cape Cod and the Islands to Missouri. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.

Search for one-way flight options from Cape Cod and the Islands to Missouri. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.

Find flight deals from Cape Cod and the Islands to Missouri

Keep the following information in mind while searching for Cape Cod and the Islands to Missouri flight deals. Data was last updated February 5, 2026.

Most accurate provider

Most trusted provider

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Cape Cod and the Islands to Missouri that are best for you.

Best time to book a flight from Cape Cod and the Islands to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Cape Cod and the Islands with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Cape Cod and the Islands to Missouri

Related info for your journey

Find useful and relevant information for your journey from Cape Cod and the Islands to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Cape Cod and the Islands to Missouri that include hotel bookings?

How can I find direct flights from Cape Cod and the Islands to Missouri?

Can I find deals for business class flights from Cape Cod and the Islands to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cape Cod and the Islands to Missouri

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Complete your trip

Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Cape Cod and the Islands to Missouri by cabin class

Find flights from Cape Cod and the Islands to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Cape Cod and the Islands and Missouri flights

Browse other Cape Cod and the Islands and Missouri flight options. Last updated on February 5, 2026.

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One-way flights from Cape Cod and the Islands to Missouri
Search for one-way flight options from Cape Cod and the Islands to Missouri. Find affordable one-way fares based on user searches. Data last updated February 5, 2026.