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$220+ Cheap flights from Roanoke (ROA) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — JAN
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Roanoke to Mississippi

Keep the following information in mind while searching for Roanoke to Mississippi flight deals. Data was last updated April 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$264
(American Airlines)

One-way from

$220
(Delta)
Provider with most accurate pricing for Roanoke-Jackson-Evers Intl flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Jackson-Evers Intl flights.
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From Roanoke to Mississippi
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One-way flight from Roanoke to Mississippi
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Find flight deals from Roanoke to Mississippi

Cheapest flights from Roanoke to Mississippi
Explore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:00 amROA - MEM
1 stop3h 48mDelta
Mon 10/67:20 pmMEM - ROA
1 stop3h 29mDelta
Deal found 4/29$249
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/135:03 pmROA - MEM
2 stops7h 41mAmerican Airlines
Sat 5/172:26 pmMEM - ROA
1 stop4h 22mAmerican Airlines
Deal found 4/28$264
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/135:03 pmROA - JAN
2 stops7h 52mAmerican Airlines
Sat 5/177:02 amJAN - ROA
1 stop4h 21mAmerican Airlines
Deal found 4/27$334
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:45 amROA - MEM
1 stop5h 13mUnited Airlines
Mon 10/67:30 amMEM - ROA
2 stops10h 14mUnited Airlines
Deal found 4/29$384
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:45 pmROA - MOB
1 stop25h 02mUnited Airlines
Sun 5/118:00 amMOB - ROA
1 stop5h 08mUnited Airlines
Deal found 4/28$604
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1310:34 amROA - JAN
3 stops12h 34mUnited Airlines
Sat 5/177:00 amJAN - ROA
2 stops8h 54mUnited Airlines
Deal found 4/27$1,135

Cheapflights Fare Finder

Customize your flight search to find flights from Roanoke to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Roanoke to Mississippi that are best for you.

Fly from

Roanoke

Fly to

Mississippi

Route

Depart

Return

Price

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Tue 5/13

5:03 pm-11:44 pm

2 stops7h 41m

Memphis

Sat 5/17

2:26 pm-7:48 pm

1 stop4h 22m

$264

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Thu 6/19

6:00 am-8:50 am

1 stop3h 50m

Memphis

Mon 6/23

9:55 am-3:05 pm

1 stop4h 10m

$279

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Tue 5/13

5:03 pm-11:55 pm

2 stops7h 52m

Jackson-Evers Intl

Sat 5/17

7:02 am-12:23 pm

1 stop4h 21m

$334

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Mon 6/16

5:35 pm-10:30 pm

1 stop5h 55m

Memphis

Wed 6/18

2:48 pm-11:35 pm

2 stops7h 47m

$444

RoanokeMobile

ROA - MOB

ROAMOB

Roanoke

Sun 5/11

7:00 am-4:12 pm

2 stops10h 12m

Mobile

Fri 5/16

5:10 pm-9:43 am

2 stops15h 33m

$607

RoanokeJackson

ROA - JAN

ROAJAN

Roanoke

Tue 5/13

10:34 am-10:08 pm

3 stops12h 34m

Jackson-Evers Intl

Sat 5/17

7:00 am-4:54 pm

2 stops8h 54m

$1,135

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Mon 6/23

6:00 am-8:50 am

1 stop3h 50m

$220

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Mon 6/23

5:25 pm-11:19 pm

2 stops6h 54m

$225

RoanokeMobile

ROA - MOB

ROAMOB

Roanoke

Tue 10/7

2:50 pm-7:10 pm

1 stop5h 20m

$255

RoanokeMemphis

ROA - MEM

ROAMEM

Roanoke

Thu 5/15

10:34 am-10:09 pm

2 stops12h 35m

$300

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Best time to book a flight from Roanoke to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Mississippi

What is the cheapest month to book a flight from Roanoke to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Roanoke to Mississippi (average of $371). Flying from Roanoke to Mississippi in March is currently the most expensive (average of $451). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to MS?

Find hourly flight availability from Roanoke to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to Mississippi as you normally would.

Rainfall in Mississippi by month

Plan your trip to Mississippi by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mississippi ranges from 2.2 - 5.6 inches per month. December is typically the wettest month, when rainfall can reach 5.6 in. October is typically the driest time to visit Mississippi when rainfall is around 2.2 in.

Temperature in Mississippi by month

Plan your trip to Mississippi by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mississippi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated April 30, 2025.
To help decide which airline to fly from Roanoke to Mississippi, see what other customers have to say about Delta, United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Mississippi?

    Most people fly from Roanoke (ROA) if they book a flight from Roanoke to Mississippi. Roanoke is conveniently located just 4.2 mi from Roanoke’s city center.

  • What are the cheapest airlines to fly from Roanoke to Mississippi one-way?

    One-way options have recently been found by users for as low as $220 on Delta. Other airlines that offer cheap prices include American Airlines from $225 and United Airlines from $255 one-way.

  • What are the most popular routes from Roanoke to Mississippi?

    Most travelers choose Roanoke - Memphis, Roanoke - Mobile or Roanoke - Columbus Golden Triangle Reg. when deciding on the best route from Roanoke to Mississippi.

  • Can I find deals for flights from Roanoke to Mississippi that include hotel bookings?

    Yes. In addition to deals on Roanoke to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Mississippi.

  • Can I find deals for business class flights from Roanoke to Mississippi?

    Yes. Cheapflights offers flight deals from Roanoke to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Roanoke to Mississippi (average of $371). Flying from Roanoke to Mississippi in March is currently the most expensive (average of $451). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Roanoke to Mississippi

Discover the top 2 airlines that operate flights from Roanoke to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$353Average$394FlexibilityNo cancel feeOn-time71%

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