$269+ Cheap flights from Roanoke (ROA) to Mississippi
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — JAN
Apr 3 — Apr 101
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Mississippi
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Cheapest flights from Roanoke to MississippiExplore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 4, 2026.
Explore the most affordable flight options available from Roanoke to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 4, 2026.
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:50 pm
ROA
- MEM
1 stop4h 36m
Delta
Sat 5/25:59 pm
MEM
- ROA
1 stop5h 26m
Delta
Deal found 3/2![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/39:55 pm
ROA
- MEM
1 stop13h 20m
Multiple Airlines
Mon 4/68:00 am
MEM
- ROA
1 stop12h 10m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:09 am
ROA
- MEM
2 stops7h 14m
American Airlines
Sat 5/26:04 am
MEM
- ROA
1 stop5h 29m
American Airlines
Deal found 3/3![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:18 pm
ROA
- MEM
1 stop5h 51m
Allegiant Air
Mon 4/68:00 am
MEM
- ROA
1 stop12h 10m
Allegiant Air
Deal found 3/1![Allegiant Air logo]()
$326
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:40 am
ROA
- MEM
1 stop5h 25m
United Airlines
Wed 6/177:15 am
MEM
- ROA
1 stop5h 18m
United Airlines
Deal found 3/2![United Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:38 pm
ROA
- MEM
1 stop5h 15m
United Airlines
Sat 10/3111:19 am
MEM
- ROA
1 stop4h 37m
United Airlines
Deal found 3/1![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
ROA
- MOB
1 stop3h 30m
Delta
Sat 8/154:15 pm
MOB
- ROA
1 stop6h 35m
Delta
Deal found 2/28![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:09 pm
ROA
- MOB
1 stop6h 08m
United Airlines
Tue 8/189:30 am
MOB
- ROA
2 stops13h 13m
United Airlines
Deal found 3/3![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:00 am
ROA
- MEM
1 stop4h 12m
American Airlines
Sat 3/287:01 am
MEM
- ROA
1 stop15h 51m
American Airlines
Deal found 3/2![American Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
ROA
- MOB
1 stop6h 55m
Delta
Tue 4/76:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 3/4![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:37 am
ROA
- MEM
1 stop7h 02m
United Airlines
Sat 4/187:30 am
MEM
- ROA
1 stop4h 59m
United Airlines
Deal found 3/3![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:00 pm
ROA
- MEM
1 stop4h 51m
American Airlines
Mon 3/3011:46 am
MEM
- ROA
1 stop11h 13m
American Airlines
Deal found 2/28![American Airlines logo]()
$363
Best flights from Roanoke to MississippiDiscover carefully curated flight deals from Roanoke to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 4, 2026.
Discover carefully curated flight deals from Roanoke to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 4, 2026.
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:50 pm
ROA
- MEM
1 stop4h 36m
Delta
Sat 5/25:59 pm
MEM
- ROA
1 stop5h 26m
Delta
Deal found 3/1![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:37 am
ROA
- MEM
1 stop7h 02m
United Airlines
Sat 5/26:00 am
MEM
- ROA
2 stops7h 13m
United Airlines
Deal found 2/28![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:00 am
ROA
- MEM
1 stop4h 12m
American Airlines
Sun 3/227:01 am
MEM
- ROA
1 stop15h 58m
American Airlines
Deal found 3/3![American Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
ROA
- MOB
1 stop3h 30m
Delta
Sat 8/154:15 pm
MOB
- ROA
1 stop6h 35m
Delta
Deal found 2/28![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:09 pm
ROA
- MOB
1 stop6h 08m
United Airlines
Tue 8/189:30 am
MOB
- ROA
2 stops13h 13m
United Airlines
Deal found 3/3![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:37 am
ROA
- MEM
1 stop7h 02m
United Airlines
Sat 4/187:30 am
MEM
- ROA
1 stop4h 59m
United Airlines
Deal found 3/3![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
ROA
- MOB
1 stop6h 55m
Delta
Mon 4/137:06 pm
MOB
- ROA
1 stop4h 19m
Delta
Deal found 3/4![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
ROA
- MOB
1 stop3h 26m
Delta
Mon 5/117:01 pm
MOB
- ROA
1 stop4h 33m
Delta
Deal found 3/1![Delta logo]()
$384
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/711:09 am
ROA
- MOB
1 stop6h 08m
American Airlines
Sat 8/155:10 am
MOB
- ROA
2 stops8h 15m
American Airlines
Deal found 2/28![American Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
ROA
- MOB
1 stop6h 55m
Delta
Mon 4/137:06 pm
MOB
- ROA
1 stop4h 19m
Delta
Deal found 3/4![Delta logo]()
$404
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:00 pm
ROA
- JAN
1 stop4h 44m
American Airlines
Tue 3/245:29 pm
JAN
- ROA
1 stop4h 30m
American Airlines
Deal found 3/3![American Airlines logo]()
$509
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:55 pm
ROA
- MEM
2 stops8h 09m
United Airlines
Mon 4/67:30 am
MEM
- ROA
1 stop4h 59m
United Airlines
Deal found 3/1![United Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
ROA
- MOB
1 stop6h 55m
Delta
Sun 4/56:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 2/28![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
ROA
- MOB
1 stop6h 55m
Delta
Sat 4/115:30 pm
MOB
- ROA
1 stop5h 34m
Delta
Deal found 3/4![Delta logo]()
$439
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:00 am
ROA
- MOB
1 stop6h 55m
Delta
Fri 4/106:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 3/4![Delta logo]()
$454
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:00 pm
ROA
- JAN
1 stop4h 44m
American Airlines
Mon 3/236:42 pm
JAN
- ROA
1 stop4h 03m
American Airlines
Deal found 2/28![American Airlines logo]()
$672
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/152:55 pm
ROA
- JAN
2 stops21h 18m
United Airlines
Mon 3/234:55 pm
JAN
- ROA
2 stops20h 14m
United Airlines
Deal found 2/28![United Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:51 pm
ROA
- MOB
1 stop4h 37m
Delta
Sun 4/126:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 3/4![Delta logo]()
$494
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/148:00 pm
ROA
- JAN
1 stop4h 44m
American Airlines
Sun 3/226:42 pm
JAN
- ROA
1 stop4h 03m
American Airlines
Deal found 3/1![American Airlines logo]()
$848
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
ROA
- JAN
1 stop5h 08m
Delta
Tue 3/247:22 am
JAN
- ROA
1 stop6h 11m
Delta
Deal found 3/1![Delta logo]()
$549
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:50 pm
ROA
- JAN
2 stops16h 23m
United Airlines
Sun 3/224:55 pm
JAN
- ROA
2 stops20h 14m
United Airlines
Deal found 3/1![United Airlines logo]()
$900
Last-minute flights from Roanoke to MississippiDiscover last-minute flight deals from Roanoke to Mississippi. Data last updated March 4, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Mississippi. Data last updated March 4, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:00 am
ROA
- MEM
1 stop4h 12m
American Airlines
Sat 3/287:01 am
MEM
- ROA
1 stop15h 51m
American Airlines
Deal found 3/2![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:00 pm
ROA
- MEM
1 stop4h 51m
American Airlines
Mon 3/3011:46 am
MEM
- ROA
1 stop11h 13m
American Airlines
Deal found 2/28![American Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:51 pm
ROA
- MOB
1 stop4h 37m
Delta
Tue 4/76:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 3/4![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:51 pm
ROA
- MOB
1 stop4h 37m
Delta
Fri 4/106:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 3/4![Delta logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:18 pm
ROA
- MEM
1 stop5h 51m
Allegiant Air
Mon 4/68:00 am
MEM
- ROA
1 stop12h 10m
Allegiant Air
Deal found 3/1![Allegiant Air logo]()
$326
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
ROA
- MOB
1 stop6h 55m
Delta
Tue 4/76:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 3/4![Delta logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/39:55 pm
ROA
- MEM
1 stop13h 20m
Multiple Airlines
Mon 4/68:00 am
MEM
- ROA
1 stop12h 10m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
ROA
- MOB
1 stop6h 55m
Delta
Tue 4/76:48 pm
MOB
- ROA
1 stop4h 16m
Delta
Deal found 3/4![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:37 am
ROA
- MEM
1 stop7h 02m
United Airlines
Sat 4/187:30 am
MEM
- ROA
1 stop4h 59m
United Airlines
Deal found 3/3![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:50 pm
ROA
- MEM
1 stop4h 36m
Delta
Sat 5/25:59 pm
MEM
- ROA
1 stop5h 26m
Delta
Deal found 3/2![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:09 am
ROA
- MEM
2 stops7h 14m
American Airlines
Sat 5/26:04 am
MEM
- ROA
1 stop5h 29m
American Airlines
Deal found 3/3![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:37 am
ROA
- MEM
1 stop7h 02m
United Airlines
Sat 5/26:00 am
MEM
- ROA
2 stops7h 13m
United Airlines
Deal found 3/2![United Airlines logo]()
$344
One-way flights from Roanoke to MississippiSearch for one-way flight options from Roanoke to Mississippi. Find affordable one-way fares based on user searches. Data last updated March 4, 2026.
Search for one-way flight options from Roanoke to Mississippi. Find affordable one-way fares based on user searches. Data last updated March 4, 2026.
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
ROA
- MOB
1 stop6h 55m
Delta
Deal found 3/1![Delta logo]()
$365
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:50 am
ROA
- MOB
2 stops12h 02m
American Airlines
Deal found 3/1![American Airlines logo]()
$674
Find flight deals from Roanoke to Mississippi
Keep the following information in mind while searching for Roanoke to Mississippi flight deals. Data was last updated March 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 4, 2026.
Use the filters below to find and compare flights from Roanoke to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Wed 4/29
7:50 pm-11:26 pm
1 stop4h 36m
Memphis
Sat 5/2
5:59 pm-12:25 am
1 stop5h 26m
$269
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Fri 8/7
6:00 am-8:30 am
1 stop3h 30m
Mobile
Sat 8/15
4:15 pm-11:50 pm
1 stop6h 35m
$343
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Wed 4/29
8:37 am-2:39 pm
1 stop7h 02m
Memphis
Sat 5/2
6:00 am-2:13 pm
2 stops7h 13m
$344
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Fri 8/14
3:09 pm-8:17 pm
1 stop6h 08m
Mobile
Tue 8/18
9:30 am-11:43 pm
2 stops13h 13m
$344
RoanokeMemphis
ROA - MEM
ROAMEM
Roanoke
Tue 4/14
8:37 am-2:39 pm
1 stop7h 02m
Memphis
Sat 4/18
7:30 am-1:29 pm
1 stop4h 59m
$359
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Mon 4/6
6:00 am-11:55 am
1 stop6h 55m
Mobile
Mon 4/13
7:06 pm-12:25 am
1 stop4h 19m
$369
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Thu 5/7
6:00 am-8:26 am
1 stop3h 26m
Mobile
Mon 5/11
7:01 pm-12:34 am
1 stop4h 33m
$384
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Thu 4/2
6:00 am-11:55 am
1 stop6h 55m
Mobile
Mon 4/13
7:06 pm-12:25 am
1 stop4h 19m
$404
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Thu 4/2
6:00 am-11:55 am
1 stop6h 55m
Mobile
Sun 4/5
6:48 pm-12:04 am
1 stop4h 16m
$419
RoanokeMobile
ROA - MOB
ROAMOB
Roanoke
Thu 4/2
6:00 am-11:55 am
1 stop6h 55m
Mobile
Sat 4/11
5:30 pm-12:04 am
1 stop5h 34m
$439
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Roanoke with our price prediction graph.
ROA-MEM
ROA-MOB
ROA-JAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Mississippi
ROA-USMS
ROA-MEM
ROA-MOB
ROA-JAN
What is the cheapest month to book a flight from Roanoke to Mississippi?
Currently, April is the cheapest month in which you can book a flight from Roanoke to Mississippi (average of $248). Flying from Roanoke to Mississippi in December is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated March 4, 2026.
Read through reviews of airlines operating flights from Roanoke to Mississippi, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.9
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Roanoke to Mississippi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Roanoke to Mississippi by cabin class
Find flights from Roanoke to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Roanoke and Mississippi flights
Browse other Roanoke and Mississippi flight options. Last updated on March 4, 2026.
Popular flight searches
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Roanoke to Mississippi flights
Consider these flights traveling from Roanoke to Mississippi.
Top 2 airlines flying from Roanoke to Mississippi
Discover the top 2 airlines that operate flights from Roanoke to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$353 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$413 | FlexibilityNo cancel fee | On-timeN/A |