HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mexico City Federal District

$170+ Cheap flights from Des Moines (DSM) to Mexico City Federal District

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
oct. 16 — oct. 231
jue. 10/16
jue. 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Mexico City Federal District with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Mexico City Federal District

Keep the following information in mind while searching for Des Moines to Mexico City Federal District flight deals. Data was last updated septiembre 16, 2025.

Round-trip from

$368
(Kiwi.com)

One-way from

$170
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$597
From Des Moines to Mexico City Federal District
Search Deals
One-way flight from Des Moines to Mexico City Federal District
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($106 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Des Moines to Mexico City Federal District

Cheapest flights from Des Moines to Mexico City Federal District
Explore the most affordable flight options available from Des Moines to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/152:37 pmDSM - MEX
1 stop27h 23mMultiple Airlines
mié. 10/228:10 amMEX - DSM
1 stop28h 42mMultiple Airlines
Deal found 9/15$368
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/228:00 amDSM - MEX
1 stop12h 50mMultiple Airlines
mié. 10/298:10 amMEX - DSM
1 stop28h 37mMultiple Airlines
Deal found 9/14$382
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/312:32 pmDSM - MEX
2 stops32h 13mMultiple Airlines
vie. 11/711:00 amMEX - DSM
1 stop11h 40mMultiple Airlines
Deal found 9/16$450
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/223:30 pmDSM - MEX
1 stop29h 30mMultiple Airlines
mar. 9/3011:45 amMEX - DSM
1 stop25h 42mMultiple Airlines
Deal found 9/15$463
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/232:37 pmDSM - MEX
2 stops32h 23mMultiple Airlines
lun. 11/1011:00 amMEX - DSM
1 stop11h 40mMultiple Airlines
Deal found 9/14$467
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/152:37 pmDSM - MEX
1 stop27h 23mMultiple Airlines
dom. 10/198:10 amMEX - DSM
1 stop28h 42mMultiple Airlines
Deal found 9/14$469

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico City Federal District that are best for you.

Fly from

Des Moines

Fly to

Mexico City Federal District

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

mié. 10/15

2:37 pm-5:00 pm

1 stop27h 23m

Mexico City Benito Juarez

mié. 10/22

8:10 am-1:52 pm

1 stop28h 42m

$368

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

vie. 10/31

2:32 pm-9:45 pm

2 stops32h 13m

Mexico City Benito Juarez

vie. 11/7

11:00 am-10:40 pm

1 stop11h 40m

$453

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

jue. 10/23

2:37 pm-5:00 pm

1 stop27h 23m

Mexico City Benito Juarez

lun. 11/10

11:00 am-10:40 pm

1 stop11h 40m

$467

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

mié. 10/22

8:00 am-7:50 pm

1 stop12h 50m

Mexico City Benito Juarez

lun. 11/10

11:00 am-10:40 pm

1 stop11h 40m

$478

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

jue. 10/30

2:32 pm-5:05 pm

1 stop27h 33m

Mexico City Benito Juarez

jue. 11/6

10:30 pm-10:40 pm

2 stops24h 10m

$483

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

mié. 10/15

2:37 pm-5:00 pm

1 stop27h 23m

Mexico City Benito Juarez

dom. 10/19

3:45 pm-1:52 pm

2 stops21h 07m

$492

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

dom. 10/5

3:43 pm-7:50 pm

1 stop29h 07m

$170

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

jue. 11/27

5:00 am-12:10 am

2 stops19h 10m

$309

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

jue. 10/30

6:05 am-7:00 pm

2 stops13h 55m

$379

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

jue. 11/27

9:51 am-7:45 pm

3 stops33h 54m

$382

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 12 results
1
2

Best time to book a flight from Des Moines to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City Federal District

What is the cheapest month to book a flight from Des Moines to Mexico City Federal District?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City Federal District (average of $387). Flying from Des Moines to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City Federal District

Get insights into the airlines that provide service to Mexico City Federal District. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City Federal District. Reviews last updated septiembre 16, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Mexico City Federal District. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mexico City Federal District?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico City Federal District. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • Can I find deals for flights from Des Moines to Mexico City Federal District that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico City Federal District?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City Federal District.

  • Can I find deals for business class flights from Des Moines to Mexico City Federal District?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico City Federal District?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City Federal District (average of $387). Flying from Des Moines to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mexico City Federal District

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Cancún flights
Omaha to Cancún flights
Cedar Rapids to Cancún flights
Des Moines to Cozumel flights
Omaha to Cozumel flights
Cedar Rapids to Cozumel flights
Omaha to San José del Cabo flights
Omaha to Mexico City flights
Moline to Cancún flights
Des Moines to San José del Cabo flights
Des Moines to Puerto Vallarta flights
Omaha to Puerto Vallarta flights
Cedar Rapids to San José del Cabo flights
Cedar Rapids to Mexico City flights
Moline to San José del Cabo flights
Moline to Cozumel flights
Des Moines to Mexico City flights
Omaha to Guadalajara flights
Cedar Rapids to Puerto Vallarta flights
Omaha to León flights
Omaha to Ixtapa flights
Des Moines to Mérida flights
Moline to Puerto Vallarta flights
Des Moines to Guadalajara flights
Omaha to Mazatlán flights
Omaha to Oaxaca flights
Des Moines to León flights
Omaha to Morelia flights
Cedar Rapids to Guadalajara flights
Omaha to Aguascalientes flights
Omaha to Monterrey flights
Waterloo to Cancún flights
La Crosse to Mexico City flights
Moline to Mexico City flights
Moline to Mérida flights
Sioux City to Cozumel flights
Moline to Guadalajara flights
Omaha to Santiago de Querétaro flights
Des Moines to Santa Maria Huatulco flights
Sioux City to Cancún flights
Sioux City to San José del Cabo flights
Moline to León flights
Cedar Rapids to Monterrey flights
Omaha to Zacatecas flights
Moline to Aguascalientes flights
Omaha to Tuxtla Gutiérrez flights
Des Moines to Saltillo flights
Des Moines to Monterrey flights
Des Moines to Morelia flights

Top 3 airlines flying from Des Moines to Mexico City Federal District

Discover the top 3 airlines that operate flights from Des Moines to Mexico City Federal District. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$373Average$582FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$633FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$537Average$742FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.