What are the cheapest airlines to fly from Des Moines to Mexico City Federal District one-way?

To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $265. Delta flights start at $308 while deals on American Airlines start at $327 one-way.

In terms of precipitation, rainfall in Mexico City Federal District ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City Federal District when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City Federal District, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Des Moines to Mexico City Federal District?

The most popular airlines flying from Des Moines to Mexico City Federal District are American Airlines, Delta and United Airlines. Something to consider prior to booking your flight.

What is the cheapest month to fly from Des Moines to Mexico City Federal District?

Flights from Des Moines to Mexico City Federal District lean towards being more expensive in December. Prices are generally better when you fly from Des Moines to Mexico City Federal District in April, with the cheapest ticket starting at $527.

What is the cheapest time of day to fly from DSM to DF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mexico City Federal District as you normally would.

What airport do you fly from for flights from Des Moines to Mexico City Federal District?

Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico City Federal District. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

How can I find direct flights from Des Moines to Mexico City Federal District?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City Federal District.

Can I find deals for business class flights from Des Moines to Mexico City Federal District?

Yes. Cheapflights offers flight deals from Des Moines to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$206+ Flights from Des Moines to Mexico City Federal District

Q: How much does it cost to fly round-trip from Des Moines to Mexico City Federal District?

Airfare is typical for this route at the moment. Des Moines to Mexico City Federal District flights typically cost between $382 and $817 in September. The cheapest round-trip price found within the last 3 days was $460 on Multiple Airlines (Sep 12-Sep 19).

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Cheap flight deals from Des Moines to Mexico City Federal District

Round-trip from	$460 (Mytrip)
One-way from	$206 (Kiwi.com)
Popular in	December
Cheapest in	April
Average price	$572

From Des Moines to Mexico City Federal District

Search Deals

One-way flight from Des Moines to Mexico City Federal District

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Des Moines to Mexico City Federal District

Cheapest flights from Des Moines to Mexico City Federal District
Explore the most affordable flight options available from Des Moines to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Fri 9/122:12 pmDSM - MEX

3 stops32h 48mMultiple Airlines

Fri 9/1911:45 amMEX - DSM

1 stop9h 44mMultiple Airlines

Deal found 7/29

$460

Wed 8/276:13 pmDSM - MEX

1 stop17h 07mAmerican Airlines

Wed 9/31:10 pmMEX - DSM

1 stop18h 54mAmerican Airlines

Deal found 7/30

$496

Mon 8/187:33 pmDSM - MEX

2 stops28h 22mFrontier

Wed 9/173:45 pmMEX - DSM

2 stops20h 55mFrontier

Deal found 7/30

$503

Sat 9/135:44 amDSM - MEX

1 stop9h 26mAeromexico

Sat 9/208:50 amMEX - DSM

2 stops12h 47mAeromexico

Deal found 7/30

$524

Best flights from Des Moines to Mexico City Federal District
Discover carefully curated flight deals from Des Moines to Mexico City Federal District that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2025.

Fri 9/122:12 pmDSM - MEX

3 stops32h 48mMultiple Airlines

Fri 9/1911:45 amMEX - DSM

1 stop9h 44mMultiple Airlines

Deal found 7/29

$460

Wed 8/276:13 pmDSM - MEX

1 stop17h 07mAmerican Airlines

Wed 9/31:10 pmMEX - DSM

1 stop18h 54mAmerican Airlines

Deal found 7/30

$496

Mon 8/187:33 pmDSM - MEX

2 stops28h 22mFrontier

Wed 9/173:45 pmMEX - DSM

2 stops20h 55mFrontier

Deal found 7/30

$503

Sat 9/135:44 amDSM - MEX

1 stop9h 26mAeromexico

Sat 9/208:50 amMEX - DSM

2 stops12h 47mAeromexico

Deal found 7/30

$524

Last-minute flights from Des Moines to Mexico City Federal District
Discover last-minute flight deals from Des Moines to Mexico City Federal District. Data last updated July 31, 2025 and is based on user searches.

Tue 8/55:35 amDSM - MEX

1 stop9h 55mAmerican Airlines

Tue 8/193:30 pmMEX - DSM

1 stop7h 44mAmerican Airlines

Deal found 7/30

$706

Tue 8/57:00 amDSM - MEX

2 stops13h 20mDelta

Tue 8/197:50 amMEX - DSM

2 stops13h 49mDelta

Deal found 7/30

$755

Tue 8/511:24 amDSM - MEX

1 stop8h 41mAeromexico

Mon 8/1112:05 amMEX - DSM

2 stops16h 40mAeromexico

Deal found 7/30

$1,083

Tue 8/56:50 pmDSM - MEX

2 stops17h 20mAir Canada

Sun 8/1712:15 amMEX - DSM

2 stops33h 24mAir Canada

Deal found 7/30

$1,448

Fri 8/81:59 pmDSM - MEX

3 stops33h 01mMultiple Airlines

Sun 8/107:55 amMEX - DSM

2 stops13h 43mMultiple Airlines

Deal found 7/30

$635

Tue 8/125:44 amDSM - MEX

2 stops11h 16mDelta

Fri 8/157:35 amMEX - DSM

2 stops14h 04mDelta

Deal found 7/29

$751

Sat 8/166:02 amDSM - MEX

1 stop10h 38mUnited Airlines

Tue 8/266:30 amMEX - DSM

1 stop6h 47mUnited Airlines

Deal found 7/30

$686

Mon 8/187:33 pmDSM - MEX

2 stops28h 22mFrontier

Wed 9/173:45 pmMEX - DSM

2 stops20h 55mFrontier

Deal found 7/30

$503

Wed 8/276:13 pmDSM - MEX

1 stop17h 07mAmerican Airlines

Wed 9/31:10 pmMEX - DSM

1 stop18h 54mAmerican Airlines

Deal found 7/30

$496

Wed 8/275:44 amDSM - MEX

2 stops17h 16mAeromexico

Wed 9/38:50 amMEX - DSM

2 stops12h 53mAeromexico

Deal found 7/30

$533

Fri 8/298:59 pmDSM - MEX

3 stops26h 01mMultiple Airlines

Sun 9/711:45 amMEX - DSM

1 stop9h 56mMultiple Airlines

Deal found 7/31

$520

One-way flights from Des Moines to Mexico City Federal District
Search for one-way flight options from Des Moines to Mexico City Federal District. Find affordable one-way fares based on user searches. Data last updated July 31, 2025.

Wed 8/62:45 pmDSM - MEX

1 stop30h 15mMultiple Airlines

Deal found 7/29

$206

Thu 10/168:44 pmDSM - MEX

1 stop21h 16mFrontier

Deal found 7/31

$265

Tue 9/92:12 pmDSM - MEX

1 stop6h 28mDelta

Deal found 7/29

$308

Sat 9/135:10 amDSM - MEX

2 stops10h 20mAmerican Airlines

Deal found 7/30

$327

Sat 9/1311:35 amDSM - MEX

3 stops26h 40mUnited Airlines

Deal found 7/30

$421

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 9/12

2:12 pm-10:00 pm

3 stops32h 48m

Mexico City Benito Juarez

Fri 9/19

11:45 am-10:29 pm

1 stop9h 44m

$460

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Wed 8/27

6:13 pm-10:20 am

1 stop17h 07m

Mexico City Benito Juarez

Wed 9/3

1:10 pm-9:04 am

1 stop18h 54m

$496

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 8/18

7:33 pm-10:55 pm

2 stops28h 22m

Mexico City Benito Juarez

Wed 9/17

3:45 pm-1:40 pm

2 stops20h 55m

$503

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sat 9/13

5:44 am-2:10 pm

1 stop9h 26m

Mexico City Benito Juarez

Sat 9/20

8:50 am-10:37 pm

2 stops12h 47m

$524

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Wed 8/6

2:45 pm-8:00 pm

1 stop30h 15m

$206

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 10/16

8:44 pm-5:00 pm

1 stop21h 16m

$265

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Tue 9/9

2:12 pm-7:40 pm

1 stop6h 28m

$308

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sat 9/13

5:10 am-2:30 pm

2 stops10h 20m

$327

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sat 9/13

11:35 am-1:15 pm

3 stops26h 40m

$421

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Des Moines to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City Federal District

What is the cheapest month to book a flight from Des Moines to Mexico City Federal District?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City Federal District (average of $388). Flying from Des Moines to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Read reviews from past customers who have flown Delta, Aeromexico, and United Airlines from Des Moines to Mexico City Federal District. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Aeromexico

7.5

Good

1,721 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,900 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Frontier

5.9

Fair

3,239 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly from for flights from Des Moines to Mexico City Federal District?
Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico City Federal District. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.
What are the cheapest airlines to fly from Des Moines to Mexico City Federal District one-way?
To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $265. Delta flights start at $308 while deals on American Airlines start at $327 one-way.
Can I find deals for flights from Des Moines to Mexico City Federal District that include hotel bookings?
Yes. In addition to deals on Des Moines to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Mexico City Federal District?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City Federal District.
Can I find deals for business class flights from Des Moines to Mexico City Federal District?
Yes. Cheapflights offers flight deals from Des Moines to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Mexico City Federal District?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City Federal District (average of $388). Flying from Des Moines to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Des Moines to Mexico City Federal District

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$373	Average$582	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$527	Average$625	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$537	Average$751	FlexibilityNo cancel fee	On-time69%

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$206+ Cheap flights from Des Moines (DSM) to Mexico City Federal District

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Mexico City Federal District with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Mexico City Federal District

Keep the following information in mind while searching for Des Moines to Mexico City Federal District flight deals. Data was last updated July 31, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Mexico City Federal District

Cheapest flights from Des Moines to Mexico City Federal DistrictExplore the most affordable flight options available from Des Moines to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Explore the most affordable flight options available from Des Moines to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City Federal District that are best for you.

Best time to book a flight from Des Moines to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City Federal District

What is the cheapest month to book a flight from Des Moines to Mexico City Federal District?

How much does it cost to fly round-trip from Des Moines to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Read reviews from past customers who have flown Delta, Aeromexico, and United Airlines from Des Moines to Mexico City Federal District. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Mexico City Federal District?

What are the cheapest airlines to fly from Des Moines to Mexico City Federal District one-way?

Can I find deals for flights from Des Moines to Mexico City Federal District that include hotel bookings?

How can I find direct flights from Des Moines to Mexico City Federal District?

Can I find deals for business class flights from Des Moines to Mexico City Federal District?

What is the cheapest month to book a flight from Des Moines to Mexico City Federal District?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mexico City Federal District

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Des Moines to Mexico City Federal District

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Travel Smart

Cheapest flights from Des Moines to Mexico City Federal District
Explore the most affordable flight options available from Des Moines to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.