$129+ Cheap flights from Odessa, TX to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — PHX
Sep 8 — Sep 151
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Odessa to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Odessa to MesaExplore the most affordable flight options available from Odessa to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
Explore the most affordable flight options available from Odessa to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:35 pm -
1 stop6h 40m
Sat 8/2212:25 pm -
1 stop5h 15m
Deal found 8/8![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:00 am -
2 stops8h 40m
Sat 9/512:25 pm -
1 stop5h 20m
Deal found 8/6![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:30 am -
1 stop8h 20m
Sun 9/63:35 pm -
1 stop4h 30m
Deal found 8/7![Southwest logo]()
$294
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:22 am -
Nonstop2h 02m
Sun 9/67:20 pm -
Nonstop1h 49m
Deal found 8/7![American Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:25 pm -
1 stop5h 10m
Thu 9/105:00 am -
1 stop6h 20m
Deal found 8/6![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:22 am -
Nonstop2h 02m
Sat 9/57:20 pm -
Nonstop1h 49m
Deal found 8/6![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:22 am -
Nonstop2h 02m
Wed 9/96:55 pm -
Nonstop1h 51m
Deal found 8/5![American Airlines logo]()
$345
Best flights from Odessa to MesaDiscover carefully curated flight deals from Odessa to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
Discover carefully curated flight deals from Odessa to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:55 pm -
1 stop7h 00m
Tue 10/205:35 am -
1 stop5h 50m
Deal found 8/8![Southwest logo]()
$257
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:34 am -
1 stop8h 19m
Sun 9/136:09 am -
1 stop5h 23m
Deal found 8/6![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:00 am -
2 stops8h 40m
Sat 9/512:25 pm -
1 stop5h 20m
Deal found 8/6![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:25 pm -
1 stop5h 10m
Thu 9/105:00 am -
1 stop6h 20m
Deal found 8/6![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:50 pm -
1 stop7h 35m
Sun 10/47:20 am -
1 stop5h 35m
Deal found 8/6![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:20 pm -
1 stop6h 30m
Wed 9/96:10 am -
1 stop5h 30m
Deal found 8/5![Southwest logo]()
$365
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:35 pm -
1 stop4h 50m
Sat 8/2212:20 pm -
2 stops6h 45m
Deal found 8/8![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:45 am -
1 stop7h 45m
Thu 9/172:00 pm -
1 stop6h 25m
Deal found 8/5![Southwest logo]()
$431
Last-minute flights from Odessa to MesaDiscover last-minute flight deals from Odessa to Mesa. Data last updated August 9, 2026 and is based on user searches.
Discover last-minute flight deals from Odessa to Mesa. Data last updated August 9, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:35 pm -
1 stop6h 40m
Sat 8/2212:25 pm -
1 stop5h 15m
Deal found 8/8![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:00 am -
2 stops8h 40m
Sat 9/512:25 pm -
1 stop5h 20m
Deal found 8/6![Southwest logo]()
$262
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:22 am -
Nonstop2h 02m
Sat 9/57:20 pm -
Nonstop1h 49m
Deal found 8/6![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:22 am -
Nonstop2h 02m
Wed 9/96:55 pm -
Nonstop1h 51m
Deal found 8/5![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:25 pm -
1 stop5h 10m
Thu 9/105:00 am -
1 stop6h 20m
Deal found 8/6![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:30 am -
1 stop8h 20m
Sun 9/63:35 pm -
1 stop4h 30m
Deal found 8/7![Southwest logo]()
$294
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:22 am -
Nonstop2h 02m
Sun 9/67:20 pm -
Nonstop1h 49m
Deal found 8/7![American Airlines logo]()
$301
One-way flights from Odessa to MesaSearch for one-way flight options from Odessa to Mesa. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
Search for one-way flight options from Odessa to Mesa. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:15 pm -
1 stop5h 20m
Deal found 8/7![Southwest logo]()
$129
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:50 pm -
1 stop7h 35m
Deal found 8/6![Southwest logo]()
$139
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:30 am -
1 stop8h 20m
Deal found 8/6![Southwest logo]()
$144
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:22 am -
Nonstop2h 02m
Deal found 8/6![American Airlines logo]()
$151
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:45 am -
1 stop5h 55m
Deal found 8/5![Southwest logo]()
$183
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:35 pm -
1 stop6h 45m
Deal found 8/5![Southwest logo]()
$204
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:40 am -
1 stop6h 48m
Deal found 8/8![United Airlines logo]()
$224
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:30 pm -
2 stops8h 50m
Deal found 8/6![Southwest logo]()
$229
Find flight deals from Odessa to Mesa
Keep the following information in mind while searching for Odessa to Mesa flight deals. Data was last updated August 9, 2026.
Round-trip from | $257 (Southwest) |
|---|---|
One-way from | $129 (Southwest) |
Popular in | March |
Cheapest in | January |
Cheapflights Fare Finder
Customize your flight search to find flights from Odessa to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Odessa to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Thu 10/15
1:55 pm-6:55 pm
1 stop7h 00m
Phoenix Sky Harbor Intl
Tue 10/20
5:35 am-1:25 pm
1 stop5h 50m
$257
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Thu 8/27
8:00 am-2:40 pm
2 stops8h 40m
Phoenix Sky Harbor Intl
Sat 9/5
12:25 pm-7:45 pm
1 stop5h 20m
$262
Quickest round-trip
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Thu 9/3
6:25 pm-9:35 pm
1 stop5h 10m
Phoenix Sky Harbor Intl
Thu 9/10
5:00 am-1:20 pm
1 stop6h 20m
$321
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Thu 10/1
5:50 pm-11:25 pm
1 stop7h 35m
Phoenix Sky Harbor Intl
Sun 10/4
7:20 am-2:55 pm
1 stop5h 35m
$362
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Wed 9/2
12:20 pm-4:50 pm
1 stop6h 30m
Phoenix Sky Harbor Intl
Wed 9/9
6:10 am-1:40 pm
1 stop5h 30m
$365
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Fri 8/14
5:35 pm-8:25 pm
1 stop4h 50m
Phoenix Sky Harbor Intl
Sat 8/22
12:20 pm-9:05 pm
2 stops6h 45m
$382
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Fri 9/11
9:34 am-3:53 pm
1 stop8h 19m
Phoenix Sky Harbor Intl
Sun 9/13
6:09 am-1:32 pm
1 stop5h 23m
$384
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Wed 8/19
6:45 am-12:30 pm
1 stop7h 45m
Phoenix Sky Harbor Intl
Thu 9/17
2:00 pm-10:25 pm
1 stop6h 25m
$431
Cheapest one-way
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Tue 10/6
4:25 pm-9:35 pm
2 stops7h 10m
$134
Quickest one-way
MidlandPhoenix
MAF Midland Intl - PHX Phoenix Sky Harbor Intl
MAFPHX
Midland Intl
Thu 11/5
8:25 pm-12:30 am
1 stop5h 05m
$139
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Odessa to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Odessa with our price prediction graph.
MAF-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Odessa to Mesa
OD3-MS9
MAF-PHX
What is the cheapest time of day to fly from OD3 to MS9?
Find hourly flight availability from Odessa to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 9, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Odessa to Mesa as you normally would.
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated August 9, 2026.
Read reviews from past customers who have flown Southwest and American Airlines from Odessa to Mesa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Odessa to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
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Odessa and Mesa flights
Browse other Odessa and Mesa flight options. Last updated on August 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mesa
Find the right flight back to Odessa after your stay in Mesa
Odessa to Mesa flights
Consider these flights traveling from Odessa to Mesa.
Top 2 airlines flying from Odessa to Mesa
Discover the top 2 airlines that operate flights from Odessa to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$272 | Average$477 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$348 | Average$461 | FlexibilityNo cancel fee | On-time63% |