HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mesa

$186+ Cheap flights from Odessa, TX to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — PHX
Jun 12 — Jun 191
Fri 6/12
Fri 6/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Odessa to Mesa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Odessa to Mesa

Cheapest flights from Odessa to Mesa
Explore the most affordable flight options available from Odessa to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.

This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:00 am
MAF
-
PHX
1 stop6h 00m
Southwest
Wed 6/31:40 pm
PHX
-
MAF
1 stop5h 30m
Southwest
Deal found 5/7$389
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:35 pm
MAF
-
PHX
1 stop6h 05m
Southwest
Tue 6/239:45 am
PHX
-
MAF
1 stop6h 45m
Southwest
Deal found 5/8$404
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:32 am
MAF
-
PHX
Nonstop2h 04m
American Airlines
Wed 6/37:20 pm
PHX
-
MAF
Nonstop1h 49m
American Airlines
Deal found 5/7$427
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:32 am
MAF
-
PHX
Nonstop2h 04m
American Airlines
Tue 6/237:20 pm
PHX
-
MAF
Nonstop1h 49m
American Airlines
Deal found 5/9$432
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:50 am
MAF
-
PHX
1 stop4h 50m
Southwest
Thu 6/253:25 pm
PHX
-
MAF
2 stops5h 40m
Southwest
Deal found 5/11$442
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:40 pm
MAF
-
PHX
1 stop7h 45m
Southwest
Wed 5/271:50 pm
PHX
-
MAF
1 stop6h 25m
Southwest
Deal found 5/12$447

Find flight deals from Odessa to Mesa

Keep the following information in mind while searching for Odessa to Mesa flight deals. Data was last updated May 13, 2026.

Round-trip from

$389
(Southwest)

One-way from

$186
(Southwest)

Popular in

October

Cheapest in

September

Average price

$477
From Odessa to Mesa
Search Deals
One-way flight from Odessa to Mesa
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Odessa to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 5/27

11:00 am-3:00 pm

1 stop6h 00m

Phoenix Sky Harbor Intl

Wed 6/3

1:40 pm-9:10 pm

1 stop5h 30m

$389

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Thu 6/18

6:05 pm-10:40 pm

2 stops6h 35m

Phoenix Sky Harbor Intl

Tue 6/23

4:50 pm-11:10 pm

1 stop4h 20m

$409

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Thu 6/25

1:30 pm-3:50 pm

1 stop4h 20m

Phoenix Sky Harbor Intl

Tue 6/30

9:25 am-6:30 pm

2 stops7h 05m

$409

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Mon 7/6

3:55 pm-6:50 pm

1 stop4h 55m

Phoenix Sky Harbor Intl

Sat 7/11

2:55 pm-10:15 pm

1 stop5h 20m

$432

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Thu 6/18

6:05 pm-11:15 pm

1 stop7h 10m

Phoenix Sky Harbor Intl

Thu 6/25

8:25 am-3:20 pm

1 stop4h 55m

$437
Quickest round-trip

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Thu 6/18

9:32 am-9:36 am

Nonstop2h 04m

Phoenix Sky Harbor Intl

Tue 6/23

4:35 pm-11:16 pm

1 stop4h 41m

$442

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sun 7/5

7:55 pm-11:05 pm

1 stop5h 10m

Phoenix Sky Harbor Intl

Fri 7/10

8:05 am-5:25 pm

2 stops7h 20m

$442
Cheapest one-way

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 8/5

7:20 am-12:20 pm

1 stop7h 00m

$186

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sun 5/24

12:05 pm-4:55 pm

2 stops6h 50m

$204
Quickest one-way

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 7/1

3:30 pm-6:10 pm

1 stop4h 40m

$204

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/10

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Odessa to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Mesa

What is the cheapest time of day to fly from OD3 to MS9?

Find hourly flight availability from Odessa to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 13, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Odessa to Mesa as you normally would.

How much does it cost to fly round-trip from Odessa to Mesa?

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated May 13, 2026.
Read reviews from past customers who have flown Southwest and American Airlines from Odessa to Mesa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
American Airlines
7.1
Good
11,661 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Related info for your journey

Find useful and relevant information for your journey from Odessa to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Mesa?

    There are many flights that can get you from Odessa to Mesa in 6h. Fly via Southwest to get the fastest option. Odessa and Mesa are separated by a distance of 578 mi.

  • What are the most reliable airlines from Odessa to Mesa?

    No one likes to see their flight delayed. When booking a flight from Odessa to Mesa consider choosing SkyWest Airlines (89%), American Airlines (89%) or Porter Airlines (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Odessa to Mesa?

    Looking for the cheapest flight from Odessa to Mesa? While on average our users pay $332, our data indicates the cheapest price to be $169. The most popular route (Midland Intl - Phoenix Sky Harbor Intl), is priced around $432.

  • Can I find deals for flights from Odessa to Mesa that include hotel bookings?

    Yes. In addition to deals on Odessa to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Mesa.

  • Can I find deals for business class flights from Odessa to Mesa?

    Yes. Cheapflights offers flight deals from Odessa to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Odessa to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Las Vegas flights
Hobby to Las Vegas flights
George Bush Intcntl to Las Vegas flights
Austin to Las Vegas flights
Dallas/Fort Worth to Sky Harbor Intl flights
Love Field to Las Vegas flights
San Antonio to Las Vegas flights
Hobby to Sky Harbor Intl flights
George Bush Intcntl to Sky Harbor Intl flights
Austin to Sky Harbor Intl flights
El Paso to Las Vegas flights
Love Field to Sky Harbor Intl flights
San Antonio to Sky Harbor Intl flights
Dallas/Fort Worth to Tucson flights
Hobby to Tucson flights
McAllen to Las Vegas flights
George Bush Intcntl to Tucson flights
El Paso to Sky Harbor Intl flights
Lubbock to Las Vegas flights
Corpus Christi to Las Vegas flights
Midland to Las Vegas flights
Amarillo to Las Vegas flights
Laredo to Las Vegas flights
Harlingen to Las Vegas flights
Lubbock to Sky Harbor Intl flights
Abilene to Las Vegas flights
Dallas/Fort Worth to Flagstaff flights
Austin to Tucson flights
Love Field to Tucson flights
Brownsville to Las Vegas flights
Dallas/Fort Worth to Yuma flights
Abilene to Sky Harbor Intl flights
Midland to Sky Harbor Intl flights
Austin to Flagstaff flights
San Antonio to Tucson flights
Corpus Christi to Sky Harbor Intl flights
George Bush Intcntl to Flagstaff flights
Killeen to Las Vegas flights
College Station to Las Vegas flights
Amarillo to Sky Harbor Intl flights
McAllen to Sky Harbor Intl flights
Laredo to Sky Harbor Intl flights
Corpus Christi to Tucson flights
Beaumont to Las Vegas flights
Tyler to Las Vegas flights
Wichita Falls to Las Vegas flights
Texarkana to Las Vegas flights
San Angelo to Las Vegas flights

Top 2 airlines flying from Odessa to Mesa

Discover the top 2 airlines that operate flights from Odessa to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$318Average$462FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$348Average$454FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.