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Mesa

$174+ Cheap flights from Odessa, TX to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — PHX
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Odessa to Mesa

Cheapest flights from Odessa to Mesa
Explore the most affordable flight options available from Odessa to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amMAF - PHX
1 stop11h 34mAmerican Airlines
Thu 12/251:30 pmPHX - MAF
Nonstop1h 47mAmerican Airlines
Deal found 12/13$384
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:00 pmMAF - PHX
1 stop7h 20mSouthwest
Thu 12/257:55 amPHX - MAF
1 stop7h 10mSouthwest
Deal found 12/13$449
This Southwest deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:45 pmMAF - PHX
1 stop5h 40mSouthwest
Mon 1/56:00 amPHX - MAF
1 stop6h 40mSouthwest
Deal found 12/15$467
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:28 pmMAF - PHX
1 stop5h 06mAmerican Airlines
Sat 12/278:10 pmPHX - MAF
Nonstop1h 47mAmerican Airlines
Deal found 12/13$486
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:41 amMAF - PHX
Nonstop2h 09mAmerican Airlines
Mon 1/58:10 pmPHX - MAF
Nonstop1h 47mAmerican Airlines
Deal found 12/13$492
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:40 pmMAF - PHX
1 stop5h 40mSouthwest
Sat 12/275:15 pmPHX - MAF
1 stop7h 05mSouthwest
Deal found 12/13$495
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:41 amMAF - PHX
Nonstop2h 09mAmerican Airlines
Mon 1/58:10 pmPHX - MAF
Nonstop1h 47mAmerican Airlines
Deal found 12/15$510
This Southwest deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:50 amMAF - PHX
1 stop7h 35mSouthwest
Sun 12/144:35 pmPHX - MAF
1 stop5h 35mSouthwest
Deal found 12/12$513

Find flight deals from Odessa to Mesa

Keep the following information in mind while searching for Odessa to Mesa flight deals. Data was last updated December 15, 2025.

Round-trip from

$347
(American Airlines)

One-way from

$174
(American Airlines)

Popular in

October

Cheapest in

September

Average price

$473
From Odessa to Mesa
Search Deals
One-way flight from Odessa to Mesa
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Odessa to Mesa that are best for you.

Fly from

Odessa

Fly to

Mesa

Route

Depart

Return

Price

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sat 1/10

6:37 am-7:50 am

Nonstop2h 13m

Phoenix Sky Harbor Intl

Sat 1/17

8:11 pm-10:53 pm

Nonstop1h 42m

$347

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Tue 1/6

10:37 am-3:38 pm

1 stop6h 01m

Phoenix Sky Harbor Intl

Mon 1/12

8:11 pm-10:53 pm

Nonstop1h 42m

$357

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sat 1/10

2:55 pm-10:14 pm

1 stop8h 19m

Phoenix Sky Harbor Intl

Sat 1/17

7:15 am-4:21 pm

1 stop8h 06m

$367

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Tue 1/6

7:05 am-11:15 am

1 stop5h 10m

Phoenix Sky Harbor Intl

Mon 1/12

7:05 am-2:05 pm

1 stop6h 00m

$367

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Mon 1/5

6:41 am-7:50 am

Nonstop2h 09m

Phoenix Sky Harbor Intl

Mon 1/12

8:11 pm-10:53 pm

Nonstop1h 42m

$383

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 12/24

6:00 am-4:34 pm

1 stop11h 34m

Phoenix Sky Harbor Intl

Thu 12/25

1:30 pm-4:17 pm

Nonstop1h 47m

$384

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Mon 1/5

7:45 am-1:45 pm

1 stop7h 00m

Phoenix Sky Harbor Intl

Mon 1/12

8:45 am-4:15 pm

1 stop6h 30m

$403

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Tue 1/13

6:37 am-7:50 am

Nonstop2h 13m

$174

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 1/14

7:00 am-12:24 pm

1 stop6h 24m

$184

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Mon 1/12

4:55 pm-8:36 pm

1 stop4h 41m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 16 results
1
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Best time to book a flight from Odessa to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Mesa

What is the cheapest month to book a flight from Odessa to Mesa?

Currently, October is the cheapest month in which you can book a flight from Odessa to Mesa (average of $288). Flying from Odessa to Mesa in December is currently the most expensive (average of $421). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OD3 to MS9?

Find hourly flight availability from Odessa to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

It’s optimal to fly from Odessa to Mesa in the morning. By choosing this option you can save up to 13% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Odessa to Mesa?

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated December 15, 2025.
Read reviews from past customers who have flown Southwest and American Airlines from Odessa to Mesa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
11,051 reviews
Southwest
7.9
Good
4,250 reviews

Overall

7.9

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Odessa to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Mesa?

    There are many flights that can get you from Odessa to Mesa in 2h 13m. Fly via American Airlines or United Airlines to get the fastest option. Odessa and Mesa are separated by a distance of 578 mi. This flight may include one or multiple stops.

  • What are the most reliable airlines from Odessa to Mesa?

    No one likes to see their flight delayed. When booking a flight from Odessa to Mesa consider choosing Envoy Air (100%), American Airlines (92%) or Alaska Airlines (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Odessa to Mesa?

    Looking for the cheapest flight from Odessa to Mesa? While on average our users pay $467, our data indicates the cheapest price to be $293. The most popular route (Midland Intl - Phoenix Sky Harbor Intl), is priced around $284.

  • Can I find deals for flights from Odessa to Mesa that include hotel bookings?

    Yes. In addition to deals on Odessa to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Mesa.

  • Can I find deals for business class flights from Odessa to Mesa?

    Yes. Cheapflights offers flight deals from Odessa to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to Mesa?

    Currently, October is the cheapest month in which you can book a flight from Odessa to Mesa (average of $288). Flying from Odessa to Mesa in December is currently the most expensive (average of $421). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Odessa to Mesa

Discover the top 3 airlines that operate flights from Odessa to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$309Average$410FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$318Average$436FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$386Average$473FlexibilityNo cancel feeOn-time63%

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