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Mesa

$132+ Cheap flights from Odessa, TX to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — PHX
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Odessa to Mesa

Cheapest flights from Odessa to Mesa
Explore the most affordable flight options available from Odessa to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:07 pm
MAF
-
PHX
1 stop5h 12m
United Airlines
Wed 4/226:05 am
PHX
-
MAF
1 stop5h 27m
United Airlines
Deal found 3/18$359
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:45 pm
MAF
-
PHX
1 stop6h 45m
Southwest
Wed 4/228:55 am
PHX
-
MAF
2 stops6h 45m
Southwest
Deal found 3/18$364
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:50 am
MAF
-
PHX
1 stop4h 40m
Southwest
Mon 4/208:05 am
PHX
-
MAF
1 stop4h 55m
Southwest
Deal found 3/19$375
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:48 am
MAF
-
PHX
Nonstop2h 02m
American Airlines
Mon 4/208:01 pm
PHX
-
MAF
Nonstop1h 45m
American Airlines
Deal found 3/19$402
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:48 am
MAF
-
PHX
Nonstop2h 02m
American Airlines
Sun 4/268:01 pm
PHX
-
MAF
Nonstop1h 45m
American Airlines
Deal found 3/22$405
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:48 am
MAF
-
PHX
Nonstop2h 02m
American Airlines
Mon 5/48:01 pm
PHX
-
MAF
Nonstop1h 45m
American Airlines
Deal found 3/22$417
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:00 am
MAF
-
PHX
1 stop4h 45m
Southwest
Sun 5/241:00 pm
PHX
-
MAF
1 stop6h 10m
Southwest
Deal found 3/21$422

Find flight deals from Odessa to Mesa

Keep the following information in mind while searching for Odessa to Mesa flight deals. Data was last updated March 23, 2026.

Round-trip from

$359
(United Airlines)

One-way from

$132
(Southwest)

Popular in

March

Cheapest in

September

Average price

$537
From Odessa to Mesa
Search Deals
One-way flight from Odessa to Mesa
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Odessa to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 4/15

2:45 pm-7:30 pm

1 stop6h 45m

Phoenix Sky Harbor Intl

Wed 4/22

8:55 am-5:40 pm

2 stops6h 45m

$364

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Fri 5/1

3:35 pm-9:15 pm

1 stop7h 40m

Phoenix Sky Harbor Intl

Mon 5/4

3:35 pm-11:10 pm

1 stop5h 35m

$369

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sat 5/16

5:30 am-9:10 am

1 stop5h 40m

Phoenix Sky Harbor Intl

Mon 5/18

6:30 am-3:15 pm

1 stop6h 45m

$375

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sat 4/18

12:15 pm-7:20 pm

2 stops9h 05m

Phoenix Sky Harbor Intl

Mon 4/20

3:50 pm-11:25 pm

1 stop5h 35m

$380
Quickest round-trip

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 4/15

6:48 am-6:50 am

Nonstop2h 02m

Phoenix Sky Harbor Intl

Wed 4/22

8:01 pm-11:46 pm

Nonstop1h 45m

$417

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sat 4/18

6:50 am-10:25 am

1 stop5h 35m

Phoenix Sky Harbor Intl

Sun 4/19

5:10 am-11:45 am

1 stop4h 35m

$417

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Wed 5/20

12:35 pm-5:55 pm

2 stops7h 20m

Phoenix Sky Harbor Intl

Sun 5/24

12:45 pm-10:15 pm

1 stop7h 30m

$427
Cheapest one-way
Quickest one-way

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Sat 6/20

1:45 pm-4:43 pm

1 stop4h 58m

$204

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Thu 6/18

6:05 pm-11:15 pm

1 stop7h 10m

$219

MidlandPhoenix

MAF - PHX

MAFPHX

Midland Intl

Thu 5/21

3:50 pm-9:10 pm

1 stop7h 20m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/21

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Odessa to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Mesa

What is the cheapest month to book a flight from Odessa to Mesa?

Currently, October is the cheapest month in which you can book a flight from Odessa to Mesa (average of $288). Flying from Odessa to Mesa in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OD3 to MS9?

Find hourly flight availability from Odessa to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 23, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Odessa to Mesa as you normally would.

Weekly flight availability from Odessa to Mesa

Explore weekly flight availability from Odessa to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 23, 2026.

The most flights from OD3 to MS9 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Odessa to Mesa?

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated March 23, 2026.
Read reviews from past customers who have flown Southwest and American Airlines from Odessa to Mesa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
American Airlines
7.1
Good
11,488 reviews
Southwest
8.0
Very good
4,324 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Related info for your journey

Find useful and relevant information for your journey from Odessa to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Mesa?

    There are many flights that can get you from Odessa to Mesa in 6h 45m. Fly via Southwest to get the fastest option. Odessa and Mesa are separated by a distance of 578 mi.

  • What are the most reliable airlines from Odessa to Mesa?

    No one likes to see their flight delayed. When booking a flight from Odessa to Mesa consider choosing Alaska Airlines (85%), SkyWest Airlines (85%) or American Airlines (85%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Odessa to Mesa?

    Looking for the cheapest flight from Odessa to Mesa? While on average our users pay $378, our data indicates the cheapest price to be $208. The most popular route (Midland Intl - Phoenix Sky Harbor Intl), is priced around $369.

  • Can I find deals for flights from Odessa to Mesa that include hotel bookings?

    Yes. In addition to deals on Odessa to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Mesa.

  • Can I find deals for business class flights from Odessa to Mesa?

    Yes. Cheapflights offers flight deals from Odessa to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to Mesa?

    Currently, October is the cheapest month in which you can book a flight from Odessa to Mesa (average of $288). Flying from Odessa to Mesa in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Odessa to Mesa

Discover the top 2 airlines that operate flights from Odessa to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$318Average$449FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$348Average$442FlexibilityNo cancel feeOn-time63%

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