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$156+ Cheap flights from San Antonio (SAT) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — MDE
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheapflights Tip: The best prices from San Antonio to Medellín are usually found in January or September, booked 74 days in advance, depart on a Monday or Tuesday and return on a Monday

Cheap flight deals from San Antonio to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Round-trip from

$367
(KAYAK)

One-way from

$156
(KAYAK)

Popular in

July

Cheapest in

January

Average price

$659
From San Antonio to Medellín
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One-way flight from San Antonio to Medellín
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Highest demand for flights based on searches. 8% potential increase in price ($57 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from San Antonio to Medellín

Cheapest flights from San Antonio to Medellín
Explore the most affordable flight options available from San Antonio to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:55 pmSAT - MDE
1 stop23h 19mSpirit Airlines
Sun 12/142:54 pmMDE - SAT
2 stops33h 32mSpirit Airlines
Deal found 11/5$367
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:55 pmSAT - MDE
1 stop23h 19mMultiple Airlines
Sat 12/132:05 amMDE - SAT
2 stops15h 46mMultiple Airlines
Deal found 11/5$368
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/308:33 pmSAT - MDE
1 stop16h 28mSpirit Airlines
Sat 12/62:05 amMDE - SAT
1 stop22h 21mSpirit Airlines
Deal found 11/5$396
This Travelocity deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:33 pmSAT - MDE
1 stop16h 28mSpirit Airlines
Sun 12/143:10 pmMDE - SAT
2 stops24h 05mSpirit Airlines
Deal found 11/6$409
This Expedia deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:37 pmSAT - MDE
1 stop17h 26mSpirit Airlines
Sun 11/161:52 amMDE - SAT
1 stop17h 40mSpirit Airlines
Deal found 11/5$436

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from San Antonio to Medellín that are best for you.

Fly from

San Antonio

Fly to

Medellín

Route

Depart

Return

Price

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 12/11

1:55 pm-2:14 pm

1 stop23h 19m

Medellín Jose Maria Cordova Intl

Sun 12/14

2:54 pm-11:26 pm

2 stops33h 32m

$367

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 11/30

8:33 pm-12:56 am

2 stops27h 23m

Medellín Jose Maria Cordova Intl

Sat 12/6

2:05 am-11:26 pm

1 stop22h 21m

$405

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 11/23

8:33 pm-2:01 pm

1 stop16h 28m

Medellín Jose Maria Cordova Intl

Sun 12/14

3:10 pm-2:15 pm

2 stops24h 05m

$409

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 11/30

8:33 pm-11:28 pm

3 stops25h 55m

Medellín Jose Maria Cordova Intl

Sat 12/6

4:39 am-11:26 pm

2 stops19h 47m

$468

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 1/22

10:26 am-2:15 pm

1 stop26h 49m

Medellín Jose Maria Cordova Intl

Fri 1/30

3:15 pm-9:30 am

1 stop19h 15m

$473

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 11/23

8:33 pm-6:17 pm

3 stops20h 44m

Medellín Jose Maria Cordova Intl

Sun 12/14

10:45 pm-11:26 pm

3 stops25h 41m

$497

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Wed 12/10

11:47 am-10:05 pm

1 stop9h 18m

Medellín Jose Maria Cordova Intl

Tue 12/16

1:15 am-8:41 am

1 stop8h 26m

$513

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 11/28

7:37 pm-12:56 am

1 stop28h 19m

$156

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 11/27

7:37 pm-9:40 pm

1 stop25h 03m

$161

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Thu 11/27

7:37 pm-12:56 am

1 stop28h 19m

$181

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 15 results
1
2

Best time to book a flight from San Antonio to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Medellín

How far ahead should I book a flight from San Antonio to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from San Antonio to Medellín. Price data was last updated on October 31, 2025.

The price you pay for your flight from San Antonio to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 73 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from San Antonio to Medellín?

Currently, May is the cheapest month in which you can book a flight from San Antonio to Medellín (average of $219). Flying from San Antonio to Medellín in June is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to MDE?

Find hourly flight availability from San Antonio to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

One of the essential ways to save on airfare from San Antonio to Medellín is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the morning could potentially save you up to 21% on airfare.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated November 6, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from San Antonio to Medellín to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,007 reviews

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,007 reviews
United Airlines
7.4
Good
9,007 reviews

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,040 reviews
United Airlines
7.4
Good
9,007 reviews

Boarding

7.7

Comfort

7.3

Crew

8.1

Entertainment

7.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to Medellín?

    San Antonio (SAT) is the airport you will fly out of if you book a flight from San Antonio to Medellín. You should not have trouble finding flights to Medellín from San Antonio; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 2 airlines have flights from the San Antonio airport to Medellín. It is only a 7.6 mi journey to San Antonio (SAT) from San Antonio’s city center.

  • How long is the flight from San Antonio to Medellín?

    A quick flight from San Antonio to Medellín can take about 23h 19m. Spirit Airlines provides one of the quickest options available for as low as $367. Airlines will cover a distance of 2203 mi.

  • What are the cheapest airlines flying from San Antonio to Medellín round-trip?

    Currently priced at $512, United Airlines will fly you from San Antonio to Medellín and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $539. You may be able to fly from San Antonio to Medellín for 16% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Antonio to Medellín that include hotel bookings?

    Yes. In addition to deals on San Antonio to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Medellín.

  • Can I find deals for business class flights from San Antonio to Medellín?

    Yes. Cheapflights offers flight deals from San Antonio to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Medellín?

    Currently, May is the cheapest month in which you can book a flight from San Antonio to Medellín (average of $219). Flying from San Antonio to Medellín in June is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from San Antonio to Medellín

Discover the top 2 airlines that operate flights from San Antonio to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$512Average$609FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$539Average$679FlexibilityNo cancel feeOn-time71%

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