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$176+ Cheap flights from San Antonio (SAT) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — MDE
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from San Antonio to Medellín

Cheapest flights from San Antonio to Medellín
Explore the most affordable flight options available from San Antonio to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:15 amSAT - MDE
1 stop15h 50mUnited Airlines
Tue 12/301:15 amMDE - SAT
1 stop15h 38mUnited Airlines
Deal found 12/25$513

Find flight deals from San Antonio to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Round-trip from

$331
(Avianca Connect)

One-way from

$176
(Cheapflightsfares)

Popular in

July

Cheapest in

January

Average price

$653
From San Antonio to Medellín
Search Deals
One-way flight from San Antonio to Medellín
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from San Antonio to Medellín that are best for you.

Fly from

San Antonio

Fly to

Medellín

Route

Depart

Return

Price

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Wed 2/25

10:26 am-9:40 pm

1 stop10h 14m

Medellín Jose Maria Cordova Intl

Mon 3/2

1:00 pm-9:30 am

1 stop21h 30m

$331

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 2/23

10:26 am-9:40 pm

1 stop10h 14m

Medellín Jose Maria Cordova Intl

Thu 2/26

1:00 pm-9:30 am

1 stop21h 30m

$344

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 1/19

10:35 am-9:40 pm

1 stop10h 05m

Medellín Jose Maria Cordova Intl

Fri 1/23

1:00 pm-9:40 am

1 stop21h 40m

$357

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 1/26

10:35 am-2:15 pm

1 stop26h 40m

Medellín Jose Maria Cordova Intl

Mon 2/2

2:50 pm-11:52 pm

1 stop10h 02m

$415

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Tue 3/31

10:26 am-6:50 pm

1 stop8h 24m

Medellín Jose Maria Cordova Intl

Tue 4/14

10:20 am-9:30 am

1 stop23h 10m

$443

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Wed 1/21

6:30 am-4:00 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Tue 1/27

10:45 pm-9:40 am

2 stops35h 55m

$499

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Wed 1/21

6:30 am-4:00 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Thu 1/29

1:00 pm-9:40 am

1 stop21h 40m

$505

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sat 4/18

5:29 am-12:40 pm

1 stop7h 11m

Medellín Jose Maria Cordova Intl

Sat 4/25

5:50 am-11:07 pm

1 stop17h 17m

$513

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 1/26

5:10 am-2:03 pm

1 stop7h 53m

Medellín Jose Maria Cordova Intl

Mon 2/2

7:00 am-4:30 pm

1 stop10h 30m

$513

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Tue 2/10

5:10 am-9:10 pm

1 stop15h 00m

Medellín Jose Maria Cordova Intl

Sun 2/15

7:00 am-11:25 pm

1 stop17h 25m

$513

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 18 results
1
2

Best time to book a flight from San Antonio to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Medellín

How far ahead should I book a flight from San Antonio to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from San Antonio to Medellín. Price data was last updated on December 26, 2025.

The price you pay for your flight from San Antonio to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 2 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from San Antonio to Medellín?

Currently, May is the cheapest month in which you can book a flight from San Antonio to Medellín (average of $219). Flying from San Antonio to Medellín in June is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Antonio to Medellín?

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 28, 2025.
Peruse reviews from past customers who have flown with United Airlines, American Airlines, and Spirit Airlines from San Antonio to Medellín to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,114 reviews

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,114 reviews
United Airlines
7.4
Good
9,114 reviews

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,071 reviews
United Airlines
7.4
Good
9,114 reviews

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
Spirit Airlines
6.3
Okay
8,214 reviews
United Airlines
7.4
Good
9,114 reviews

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to Medellín?

    San Antonio (SAT) is the airport you will fly out of if you book a flight from San Antonio to Medellín. You should not have trouble finding flights to Medellín from San Antonio; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the San Antonio airport to Medellín. It is only a 7.6 mi journey to San Antonio (SAT) from San Antonio’s city center.

  • How long is the flight from San Antonio to Medellín?

    A quick flight from San Antonio to Medellín can take about 26h 40m. Spirit Airlines provides one of the quickest options available for as low as $415. Airlines will cover a distance of 2203 mi.

  • What are the cheapest airlines flying from San Antonio to Medellín round-trip?

    Currently priced at $285, Spirit Airlines will fly you from San Antonio to Medellín and back. In addition to Spirit Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $512 and $555, respectively. You may be able to fly from San Antonio to Medellín for 53% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Antonio to Medellín that include hotel bookings?

    Yes. In addition to deals on San Antonio to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Medellín.

  • Can I find deals for business class flights from San Antonio to Medellín?

    Yes. Cheapflights offers flight deals from San Antonio to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Medellín?

    Currently, May is the cheapest month in which you can book a flight from San Antonio to Medellín (average of $219). Flying from San Antonio to Medellín in June is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from San Antonio to Medellín

Discover the top 3 airlines that operate flights from San Antonio to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$285Average$345FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$512Average$608FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$555Average$691FlexibilityNo cancel feeOn-time71%

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