What are the cheapest airlines flying from Guatemala City to Medellín round-trip?

Currently priced at $209, Copa Airlines will fly you from Guatemala City to Medellín and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Avianca for as low as $219. Copa Airlines is currently priced 28% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Guatemala City to Medellín one-way?

The cheapest airline one-way is Arajet, with whom users have recently found tickets for as low as $140. However, be on the lookout for offers from Spirit Airlines and Avianca, as they are both options that can get you from Guatemala City to Medellín for a low price.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Where are the most common layover locations when flying from Guatemala City to Medellín?

The most popular layover on flights from Guatemala City to Medellín is Panama City.

Where are the least popular layover locations for Guatemala City to Medellín flights?

Guatemala City to Medellín flights that have layovers will least frequently stop in Bogotá.

What are some popular things to do or see while on a layover in Panama City?

Panama Old Cathedral, Amador Causeway, and Panama Canal are the most popular attractions in Panama City if you're in need of something to do during your layover. Panama Old Cathedral, Amador Causeway, and Panama Canal can be accessed by traveling approximately 13.2 mi, 14.7 mi, and 15.1 mi, respectively from Panama City Tocumen Intl. Travelers can book a car rental at Panama City Tocumen Intl for about $14 per day to make their sightseeing more efficient.

What is the cheapest day to fly round-trip from Guatemala City to Medellín?

Users have found that leaving on a Sunday can be a cost-effective option. It’s possible to save up to 8% on your flight compared to booking on days when demand is much higher.

How far in advance should I book a flight from Guatemala City to Medellín?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 58 days in advance, which can save you up to 14% on flights from Guatemala City to Medellín compared to booking the week you need them. Waiting 58 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $276. For sooner than that we have options available in the next 3 days from $324.

What is the cheapest month to fly from Guatemala City to Medellín?

Our data shows that May tends to be the cheapest month to fly to Medellín from Guatemala City. Users have commonly found prices around $293 for the month, but tickets can be as low as $196. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly from for flights from Guatemala City to Medellín?

For a flight from Guatemala City to Medellín, you will be flying from La Aurora. Guatemala City La Aurora (GUA) is just 3.7 mi from the center of the city. La Aurora is the only Guatemala City airport and it handles 0 outbound flights to Medellín per day. 2 airlines have flights to Medellín from Guatemala City La Aurora on a regular basis.

Can I find deals for flights from Guatemala City to Medellín that include hotel bookings?

Yes. In addition to deals on Guatemala City to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Guatemala City to Medellín?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to Medellín.

Can I find deals for business class flights from Guatemala City to Medellín?

Yes. Cheapflights offers flight deals from Guatemala City to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$140+ Flights from Guatemala City to Medellín

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Cheapflights Tip: The best prices from Guatemala City La Aurora to Medellín are usually found in May or July, booked 84 days in advance, depart on a Monday or Sunday and return on a Wednesday

Cheap flight deals from Guatemala City to Medellín

Round-trip from	$277 (FlightHub)
One-way from	$140 (Arajet)
Popular in	December
Cheapest in	May
Average price	$304

From Guatemala City La Aurora to Medellín

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One-way flight from Guatemala City La Aurora to Medellín

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Highest demand for flights based on searches. 5% potential increase in price ($17 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Guatemala City to Medellín

Cheapest flights from Guatemala City to Medellín
Explore the most affordable flight options available from Guatemala City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Sun 9/712:20 pmGUA - MDE

1 stop11h 08mSpirit Airlines

Thu 9/111:24 amMDE - GUA

1 stop11h 01mSpirit Airlines

Deal found 8/12

$277

Mon 9/158:35 pmGUA - MDE

1 stop11h 55mArajet

Fri 9/199:27 pmMDE - GUA

1 stop11h 13mArajet

Deal found 8/13

$278

Mon 10/279:30 amGUA - MDE

1 stop9h 10mArajet

Tue 11/410:17 amMDE - GUA

1 stop8h 13mArajet

Deal found 8/12

$291

Mon 9/112:34 amGUA - MDE

2 stops11h 30mSpirit Airlines

Thu 9/41:24 amMDE - GUA

1 stop11h 01mSpirit Airlines

Deal found 8/12

$298

Sun 10/512:20 pmGUA - MDE

1 stop11h 08mSpirit Airlines

Wed 10/81:24 amMDE - GUA

1 stop11h 01mSpirit Airlines

Deal found 8/12

$300

Mon 11/109:30 amGUA - MDE

1 stop9h 10mArajet

Sat 11/1510:05 amMDE - GUA

1 stop8h 25mArajet

Deal found 8/11

$301

Fri 9/512:20 pmGUA - MDE

1 stop11h 08mSpirit Airlines

Fri 9/122:00 pmMDE - GUA

2 stops22h 25mSpirit Airlines

Deal found 8/12

$320

Thu 10/3012:20 pmGUA - MDE

1 stop11h 05mSpirit Airlines

Sat 11/12:24 amMDE - GUA

1 stop10h 51mSpirit Airlines

Deal found 8/12

$322

Thu 9/48:20 pmGUA - MDE

1 stop4h 45mAvianca

Tue 9/93:15 amMDE - GUA

1 stop6h 50mAvianca

Deal found 8/12

$323

Mon 9/18:20 pmGUA - MDE

1 stop4h 45mAvianca

Tue 9/308:53 amMDE - GUA

1 stop7h 21mAvianca

Deal found 8/13

$324

Sun 10/58:20 pmGUA - MDE

1 stop4h 45mAvianca

Thu 10/911:54 amMDE - GUA

1 stop6h 21mAvianca

Deal found 8/12

$325

Best flights from Guatemala City to Medellín
Discover carefully curated flight deals from Guatemala City to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Sun 10/512:27 pmGUA - MDE

1 stop10h 50mSpirit Airlines

Wed 10/81:12 amMDE - GUA

1 stop11h 10mSpirit Airlines

Deal found 8/14

$300

Fri 10/108:20 pmGUA - MDE

1 stop4h 45mAvianca

Mon 10/137:56 pmMDE - GUA

1 stop6h 29mAvianca

Deal found 8/13

$324

Fri 9/195:39 amGUA - MDE

2 stops7h 36mCopa Airlines

Tue 9/234:30 pmMDE - GUA

2 stops6h 06mCopa Airlines

Deal found 8/12

$327

Thu 10/212:20 pmGUA - MDE

1 stop11h 08mSpirit Airlines

Mon 10/61:12 amMDE - GUA

1 stop11h 10mSpirit Airlines

Deal found 8/14

$300

Sat 10/118:20 pmGUA - MDE

1 stop4h 45mAvianca

Mon 10/137:56 pmMDE - GUA

1 stop6h 29mAvianca

Deal found 8/14

$324

Sun 10/55:39 amGUA - MDE

2 stops8h 02mCopa Airlines

Thu 10/93:29 pmMDE - GUA

2 stops7h 07mCopa Airlines

Deal found 8/12

$327

Tue 9/912:20 pmGUA - MDE

1 stop11h 08mSpirit Airlines

Mon 9/151:24 amMDE - GUA

1 stop11h 01mSpirit Airlines

Deal found 8/14

$300

Sun 8/248:20 pmGUA - MDE

1 stop4h 45mAvianca

Sun 8/311:25 pmMDE - GUA

2 stops6h 10mAvianca

Deal found 8/14

$326

Mon 10/275:39 amGUA - MDE

2 stops10h 21mCopa Airlines

Tue 11/410:46 amMDE - GUA

2 stops11h 52mCopa Airlines

Deal found 8/12

$327

Sun 10/58:20 pmGUA - MDE

1 stop4h 45mAvianca

Thu 10/910:03 amMDE - GUA

1 stop6h 11mAvianca

Deal found 8/14

$326

Thu 8/285:20 amGUA - MDE

2 stops6h 10mAvianca

Mon 9/13:15 amMDE - GUA

1 stop6h 50mAvianca

Deal found 8/14

$326

Last-minute flights from Guatemala City to Medellín
Discover last-minute flight deals from Guatemala City to Medellín. Data last updated August 14, 2025 and is based on user searches.

Tue 8/196:35 amGUA - MDE

1 stop5h 28mAvianca

Sun 8/2411:00 amMDE - GUA

1 stop7h 15mAvianca

Deal found 8/13

$328

Wed 8/205:20 amGUA - MDE

2 stops6h 10mAvianca

Sun 8/241:25 pmMDE - GUA

2 stops6h 10mAvianca

Deal found 8/12

$326

Wed 8/205:20 amGUA - MDE

2 stops6h 10mAvianca

Sun 8/2411:20 amMDE - GUA

1 stop6h 55mAvianca

Deal found 8/12

$326

Thu 8/215:20 amGUA - MDE

2 stops6h 10mAvianca

Sun 8/243:15 amMDE - GUA

1 stop6h 50mAvianca

Deal found 8/13

$349

Fri 8/225:39 amGUA - MDE

2 stops7h 36mCopa Airlines

Wed 8/273:29 pmMDE - GUA

2 stops7h 08mCopa Airlines

Deal found 8/13

$335

Sat 8/237:11 amGUA - MDE

1 stop14h 40mCopa Airlines

Wed 8/2712:46 pmMDE - GUA

1 stop7h 57mCopa Airlines

Deal found 8/13

$327

Sat 8/235:20 amGUA - MDE

2 stops6h 10mAvianca

Tue 8/263:15 amMDE - GUA

1 stop6h 50mAvianca

Deal found 8/13

$351

Sun 8/248:20 pmGUA - MDE

1 stop4h 45mAvianca

Sun 8/311:25 pmMDE - GUA

2 stops6h 10mAvianca

Deal found 8/12

$325

Mon 9/112:34 amGUA - MDE

2 stops11h 30mSpirit Airlines

Thu 9/41:24 amMDE - GUA

1 stop11h 01mSpirit Airlines

Deal found 8/12

$298

Mon 9/18:20 pmGUA - MDE

1 stop4h 45mAvianca

Tue 9/308:53 amMDE - GUA

1 stop7h 21mAvianca

Deal found 8/13

$324

Thu 9/48:20 pmGUA - MDE

1 stop4h 45mAvianca

Tue 9/93:15 amMDE - GUA

1 stop6h 50mAvianca

Deal found 8/12

$323

Fri 9/512:20 pmGUA - MDE

1 stop11h 08mSpirit Airlines

Thu 9/111:24 amMDE - GUA

1 stop11h 01mSpirit Airlines

Deal found 8/12

$300

One-way flights from Guatemala City to Medellín
Search for one-way flight options from Guatemala City to Medellín. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Mon 12/299:30 amGUA - MDE

1 stop9h 10mArajet

Deal found 8/12

$140

Wed 9/1012:20 pmGUA - MDE

1 stop11h 08mSpirit Airlines

Deal found 8/12

$143

Sat 11/15:10 amGUA - MDE

1 stop6h 45mAvianca

Deal found 8/13

$162

Sun 8/318:20 pmGUA - MDE

1 stop4h 45mAvianca

Deal found 8/12

$163

Sat 8/305:20 amGUA - MDE

2 stops6h 10mAvianca

Deal found 8/12

$164

Fri 9/129:40 amGUA - MDE

1 stop6h 05mAvianca

Deal found 8/13

$166

Tue 9/168:20 pmGUA - MDE

2 stops8h 54mAvianca

Deal found 8/11

$168

Sun 11/161:59 amGUA - MDE

1 stop11h 17mSpirit Airlines

Deal found 8/13

$171

Sun 12/284:21 amGUA - MDE

1 stop9h 23mCopa Airlines

Deal found 8/12

$176

Mon 12/15:39 amGUA - MDE

2 stops8h 05mCopa Airlines

Deal found 8/14

$184

Fri 8/2912:34 amGUA - MDE

1 stop22h 20mSpirit Airlines

Deal found 8/12

$185

Cheapflights Fare Finder

Use the filters below to find and compare flights from Guatemala City to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Sun 10/5

12:27 pm-12:17 am

1 stop10h 50m

Medellín Jose Maria Cordova Intl

Wed 10/8

1:12 am-11:22 am

1 stop11h 10m

$300

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Thu 10/2

12:20 pm-12:28 am

1 stop11h 08m

Medellín Jose Maria Cordova Intl

Mon 10/6

1:12 am-11:22 am

1 stop11h 10m

$300

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Tue 9/9

12:20 pm-12:28 am

1 stop11h 08m

Medellín Jose Maria Cordova Intl

Mon 9/15

1:24 am-11:25 am

1 stop11h 01m

$300

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Fri 10/10

8:20 pm-2:05 am

1 stop4h 45m

Medellín Jose Maria Cordova Intl

Mon 10/13

7:56 pm-1:25 am

1 stop6h 29m

$324

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Sat 10/11

8:20 pm-2:05 am

1 stop4h 45m

Medellín Jose Maria Cordova Intl

Mon 10/13

7:56 pm-1:25 am

1 stop6h 29m

$324

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Sun 8/24

8:20 pm-2:05 am

1 stop4h 45m

Medellín Jose Maria Cordova Intl

Sun 8/31

1:25 pm-6:35 pm

2 stops6h 10m

$326

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Sun 10/5

8:20 pm-2:05 am

1 stop4h 45m

Medellín Jose Maria Cordova Intl

Thu 10/9

10:03 am-3:14 pm

1 stop6h 11m

$326

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Thu 8/28

5:20 am-12:30 pm

2 stops6h 10m

Medellín Jose Maria Cordova Intl

Mon 9/1

3:15 am-9:05 am

1 stop6h 50m

$326

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Fri 9/19

5:39 am-2:15 pm

2 stops7h 36m

Medellín Jose Maria Cordova Intl

Tue 9/23

4:30 pm-9:36 pm

2 stops6h 06m

$327

Guatemala CityMedellín

GUA - MDE

GUAMDE

Guatemala City La Aurora

Sun 10/5

5:39 am-2:41 pm

2 stops8h 02m

Medellín Jose Maria Cordova Intl

Thu 10/9

3:29 pm-9:36 pm

2 stops7h 07m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 20 results

Best time to book a flight from Guatemala City to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Guatemala City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guatemala City to Medellín

How far ahead should I book a flight from Guatemala City to Medellín?

Booking 84 days in advance of your planned departure date is, on average, the best time to get cheap flights from Guatemala City to Medellín. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Guatemala City to Medellín?

Currently, January is the cheapest month in which you can book a flight from Guatemala City to Medellín (average of $378). Flying from Guatemala City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GUA to MDE?

A simple way to save on the total cost of your ticket is to fly from Guatemala City to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 6% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Guatemala City to Medellín?

Travelers seeking maximum savings on their Guatemala City to Medellín flight should consider departing on Thursday at noon when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Medellín

Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Guatemala City to Medellín to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Copa Airlines

7.5

Good

1,507 reviews

Reviews

1 / 20

4.0

Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Copa Airlines

7.5

Good

1,507 reviews

Copa Airlines

7.5

Good

1,507 reviews

Reviews

1 / 20

4.0

Okay

Paul,Jun 2025

PTY - MIA

Avianca

6.7

Okay

2,399 reviews

Copa Airlines

7.5

Good

1,507 reviews

Reviews

1 / 20

4.0

Okay

Paul,Jun 2025

PTY - MIA

Related info for your journey

What airport do you fly from for flights from Guatemala City to Medellín?
For a flight from Guatemala City to Medellín, you will be flying from La Aurora. Guatemala City La Aurora (GUA) is just 3.7 mi from the center of the city. La Aurora is the only Guatemala City airport and it handles 0 outbound flights to Medellín per day. 2 airlines have flights to Medellín from Guatemala City La Aurora on a regular basis.
What are the cheapest airlines flying from Guatemala City to Medellín round-trip?
Currently priced at $209, Copa Airlines will fly you from Guatemala City to Medellín and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Avianca for as low as $219. Copa Airlines is currently priced 28% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Guatemala City to Medellín one-way?
The cheapest airline one-way is Arajet, with whom users have recently found tickets for as low as $140. However, be on the lookout for offers from Spirit Airlines and Avianca, as they are both options that can get you from Guatemala City to Medellín for a low price.
Where are the most common layover locations when flying from Guatemala City to Medellín?
The most popular layover on flights from Guatemala City to Medellín is Panama City.
What are some popular things to do or see while on a layover in Panama City?
Panama Old Cathedral, Amador Causeway, and Panama Canal are the most popular attractions in Panama City if you're in need of something to do during your layover. Panama Old Cathedral, Amador Causeway, and Panama Canal can be accessed by traveling approximately 13.2 mi, 14.7 mi, and 15.1 mi, respectively from Panama City Tocumen Intl. Travelers can book a car rental at Panama City Tocumen Intl for about $14 per day to make their sightseeing more efficient.
Where are the least popular layover locations for Guatemala City to Medellín flights?
Guatemala City to Medellín flights that have layovers will least frequently stop in Bogotá.
Can I find deals for flights from Guatemala City to Medellín that include hotel bookings?
Yes. In addition to deals on Guatemala City to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Guatemala City to Medellín?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to Medellín.
Can I find deals for business class flights from Guatemala City to Medellín?
Yes. Cheapflights offers flight deals from Guatemala City to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Guatemala City to Medellín?
Currently, January is the cheapest month in which you can book a flight from Guatemala City to Medellín (average of $378). Flying from Guatemala City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Guatemala City to Medellín

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$203	Average$312	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$209	Average$300	FlexibilityNo cancel fee	On-time70%

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$140+ Cheap flights from Guatemala City (GUA) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Guatemala City to Medellín with Cheapflights

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Cheapflights Tip: The best prices from Guatemala City La Aurora to Medellín are usually found in May or July, booked 84 days in advance, depart on a Monday or Sunday and return on a Wednesday

Cheap flight deals from Guatemala City to Medellín

Round-trip from

One-way from

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Find flight deals from Guatemala City to Medellín

Cheapest flights from Guatemala City to MedellínExplore the most affordable flight options available from Guatemala City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from Guatemala City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Guatemala City to Medellín that are best for you.

Best time to book a flight from Guatemala City to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Guatemala City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Guatemala City to Medellín

How far ahead should I book a flight from Guatemala City to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Guatemala City to Medellín. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Guatemala City to Medellín?

What is the cheapest time of day to fly from GUA to MDE?

Find hourly flight availability from Guatemala City to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

What is the cheapest day to fly from Guatemala City to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Guatemala City to Medellín. Price data was last updated on December 16, 2024.

Reviews of airlines servicing Medellín

Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Guatemala City to Medellín to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Guatemala City to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Guatemala City to Medellín?

What are the cheapest airlines flying from Guatemala City to Medellín round-trip?

What are the cheapest airlines to fly from Guatemala City to Medellín one-way?

Where are the most common layover locations when flying from Guatemala City to Medellín?

What are some popular things to do or see while on a layover in Panama City?

Where are the least popular layover locations for Guatemala City to Medellín flights?

Can I find deals for flights from Guatemala City to Medellín that include hotel bookings?

How can I find direct flights from Guatemala City to Medellín?

Can I find deals for business class flights from Guatemala City to Medellín?

What is the cheapest month to book a flight from Guatemala City to Medellín?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Guatemala City to Medellín

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Guatemala City to Medellín

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Cheapest flights from Guatemala City to Medellín
Explore the most affordable flight options available from Guatemala City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.