Medellín

$226+ Cheap flights from Chicago (CHI) to Medellín

CHI — MDE
Dec 9 — Dec 161
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Cheap flight deals from Chicago to Medellín

Cheapest flights from Chicago to Medellín

Sat 11/142:13 pm -
1 stop23h 02m
Tue 11/1712:40 pm -
1 stop25h 06m
Deal found 11/5$488
Sat 11/142:13 pm -
1 stop19h 42m
Wed 12/912:40 pm -
1 stop12h 31m
Deal found 11/6$494
Fri 11/272:13 pm -
1 stop17h 02m
Sun 12/139:15 am -
1 stop28h 31m
Deal found 11/6$498
Sat 11/1410:30 pm -
1 stop13h 10m
Mon 12/710:05 am -
1 stop11h 25m
Deal found 11/7$500
Fri 11/137:35 am -
1 stop12h 00m
Tue 11/1710:45 am -
1 stop14h 26m
Deal found 11/5$508
Tue 12/295:47 pm -
1 stop17h 13m
Sun 1/311:10 pm -
1 stop12h 45m
Deal found 11/6$516
Fri 11/272:13 pm -
1 stop23h 32m
Sat 12/128:35 am -
1 stop16h 36m
Deal found 11/6$518
Mon 11/166:55 am -
1 stop14h 15m
Sat 11/2110:40 am -
1 stop12h 00m
Deal found 11/5$521
Sun 11/2910:30 pm -
1 stop10h 30m
Sun 12/610:05 am -
1 stop11h 25m
Deal found 11/9$523
Sat 11/286:00 am -
2 stops15h 50m
Fri 12/115:05 am -
2 stops18h 49m
Deal found 11/6$634
Thu 12/108:37 pm -
1 stop14h 23m
Mon 12/141:10 pm -
2 stops23h 23m
Deal found 11/5$655
Fri 12/116:11 pm -
1 stop16h 49m
Sun 12/131:10 pm -
1 stop29h 06m
Deal found 11/5$665

Find flight deals from Chicago to Medellín

Round-trip from

$481
(Justfly.com)

One-way from

$226
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$486
From Chicago (CHI) to Medellín
One-way flight from Chicago (CHI) to Medellín
Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Chicago to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Mon 1/18

6:17 pm-12:07 am

2 stops28h 50m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$227

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Mon 1/11

5:41 pm-12:00 pm

2 stops41h 19m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$236
Quickest round-trip

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Thu 12/31

5:58 pm-5:35 am

1 stop10h 37m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$240

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Mon 12/28

8:35 pm-12:00 pm

1 stop14h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$242

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Sun 1/24

7:10 am-11:55 pm

2 stops15h 45m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$248

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Sat 1/16

6:00 am-8:00 pm

2 stops13h 00m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$248

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Wed 2/17

8:47 pm-12:00 pm

1 stop14h 13m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$249

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Tue 11/24

7:35 am-8:15 am

1 stop23h 40m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$254

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Fri 11/27

2:13 pm-10:55 am

1 stop19h 42m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$254

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Tue 11/17

2:13 pm-8:15 am

1 stop17h 02m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Chicago to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Chicago with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Chicago to Medellín

What is the cheapest month to book a flight from Chicago to Medellín?

Currently, February is the cheapest month in which you can book a flight from Chicago to Medellín (average of $370). Flying from Chicago to Medellín in December is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Chicago to Medellín?

Airfare is typical for this route at the moment.
Chicago to Medellín flights typically cost between $427 and $540 in February.
The cheapest round-trip price found within the last 5 days was $481 on Frontier (Feb 9-Feb 15).

How far ahead should I book a flight from Chicago to Medellín?

The best time to book flights from Chicago to Medellín is 16 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Medellín

Peruse reviews from past customers who have flown with Copa Airlines,United Airlines, andAmerican Airlines from Chicago to Medellín to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.1

Boarding

7.8

Food

7.0

Entertainment

6.9

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Crew

8.1

Boarding

7.8

Food

7.0

Entertainment

6.9

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Crew

8.1

Boarding

7.8

Food

7.0

Entertainment

6.9

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Crew

8.1

Boarding

7.8

Food

7.0

Entertainment

6.9

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Crew

8.1

Boarding

7.8

Food

7.0

Entertainment

6.9

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Related info for your journey

  • How long is the flight from Chicago to Medellín?

    For as low as $521, United Airlines can have you in Medellín from Chicago in 10h 40m. Chicago and Medellín are separated by a distance of 2589 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Chicago to Medellín round-trip?

    According to our current data, JetBlue ($161), Copa Airlines ($287), and Avianca ($301) offers the cheapest pricing from Chicago to Medellín. These flights start at 66% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Chicago to Medellín one-way?

    The cheapest airlines for a one-way flight from Chicago to Medellín are Copa Airlines ($143), Avianca ($158), and American Airlines ($185).

  • What are the most popular routes from Chicago to Medellín?

  • Can I find deals for flights from Chicago to Medellín that include hotel bookings?

    Yes. In addition to deals on Chicago to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Medellín.

  • Can I find deals for business class flights from Chicago to Medellín?

    Yes. Cheapflights offers flight deals from Chicago to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Medellín?

    Currently, February is the cheapest month in which you can book a flight from Chicago to Medellín (average of $370). Flying from Chicago to Medellín in December is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Chicago to Medellín

AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$161Average$661FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$287Average$503FlexibilityNo cancel feeOn-time70%
AviancaCheapest$301Average$502FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$319Average$587FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$427Average$645FlexibilityNo cancel feeOn-time71%
ArajetCheapest$450Average$585FlexibilityNo cancel feeOn-timeN/A

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