Medellín

$227+ Cheap flights from Chicago (CHI) to Medellín

CHI — MDE
Dec 3 — Dec 101
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Cheap flight deals from Chicago to Medellín

Cheapest flights from Chicago to Medellín

Sat 11/1410:30 pm -
1 stop10h 30m
Wed 11/1810:20 am -
1 stop11h 10m
Deal found 11/2$483
Sat 11/1410:30 pm -
1 stop10h 45m
Mon 12/710:05 am -
1 stop11h 25m
Deal found 11/2$485
Sun 11/152:13 pm -
1 stop17h 02m
Sat 12/128:35 am -
1 stop16h 36m
Deal found 11/3$488
Mon 11/22:13 pm -
1 stop23h 32m
Mon 11/164:30 pm -
1 stop21h 16m
Deal found 10/30$492
Sat 12/125:24 pm -
1 stop17h 36m
Tue 12/151:10 pm -
1 stop12h 58m
Deal found 11/1$495
Thu 11/122:13 pm -
1 stop17h 02m
Sun 11/1512:40 pm -
1 stop25h 06m
Deal found 10/30$500
Wed 11/46:00 am -
1 stop16h 34m
Mon 11/93:12 pm -
1 stop17h 48m
Deal found 11/1$503
Thu 11/122:13 pm -
1 stop19h 42m
Mon 11/164:30 pm -
1 stop8h 41m
Deal found 10/30$504
Thu 11/56:55 am -
1 stop14h 15m
Tue 1/2610:40 am -
1 stop10h 23m
Deal found 10/29$505
Fri 10/307:29 am -
1 stop13h 46m
Thu 1/2810:40 am -
1 stop13h 19m
Deal found 10/29$507
Fri 11/62:13 pm -
1 stop23h 32m
Sun 11/812:40 pm -
1 stop25h 06m
Deal found 10/30$508
Thu 12/108:37 pm -
1 stop14h 23m
Tue 12/151:10 pm -
2 stops23h 23m
Deal found 11/1$554

Find flight deals from Chicago to Medellín

Round-trip from

$483
(Avianca)

One-way from

$227
(Copa Airlines)

Popular in

December

Cheapest in

February

Average price

$468
From Chicago (CHI) to Medellín
One-way flight from Chicago (CHI) to Medellín
Highest demand for flights based on searches. 4% potential increase in price ($23 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Chicago to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Fri 1/29

5:30 am-6:05 pm

2 stops35h 35m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$238

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Sat 1/2

8:35 pm-12:00 pm

1 stop14h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$239

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Thu 11/26

2:13 pm-8:15 am

1 stop17h 02m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$244

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Wed 12/30

9:43 pm-5:35 am

1 stop30h 52m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$246

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Sun 1/3

7:00 am-5:35 am

1 stop21h 35m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$246

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Sat 1/30

3:55 pm-10:10 pm

1 stop29h 15m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$246

ChicagoMedellín

ORD Chicago O'Hare Intl - MDE Medellín Jose Maria Cordova Intl

ORDMDE

Chicago O'Hare Intl

Wed 11/11

2:13 pm-5:00 pm

1 stop25h 47m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$247

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Mon 11/9

6:17 pm-10:57 pm

2 stops27h 40m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$265

ChicagoMedellín

MDW Chicago Midway - MDE Medellín Jose Maria Cordova Intl

MDWMDE

Chicago Midway

Thu 12/10

8:37 pm-12:00 pm

1 stop14h 23m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$268

ChicagoMedellín

ORD Chicago O'Hare Intl - EOH Medellín Enrique Olaya

ORDEOH

Chicago O'Hare Intl

Mon 2/1

5:32 pm-5:15 pm

3 stops22h 43m

Medellín Enrique Olaya

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$287

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 55 resultsSorted by cheapest first
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Best time to book a flight from Chicago to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Chicago with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Chicago to Medellín

What is the cheapest month to book a flight from Chicago to Medellín?

Currently, February is the cheapest month in which you can book a flight from Chicago to Medellín (average of $370). Flying from Chicago to Medellín in December is currently the most expensive (average of $663). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Chicago to Medellín?

Airfare is typical for this route at the moment.
Chicago to Medellín flights typically cost between $424 and $532 in November.
The cheapest round-trip price found within the last 5 days was $483 on Avianca (Nov 14-Nov 18).

How far ahead should I book a flight from Chicago to Medellín?

The best time to book flights from Chicago to Medellín is 16 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Medellín

Peruse reviews from past customers who have flown with Copa Airlines,United Airlines, andAmerican Airlines from Chicago to Medellín to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Food

7.0

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Food

7.0

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Food

7.0

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Food

7.0

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Marcos,Nov 2026

BOS - PTY

Not good. Boarding was delayed about 30/40min which made my making my connection very stressful. On top of that, the accommodations (seating, entertainment, and food) were subpar -- to say the least. I've traveled a lot between the US and Argentina and this may have been my worst experience yet.

Related info for your journey

  • How long is the flight from Chicago to Medellín?

    For as low as $486, Avianca can have you in Medellín from Chicago in 9h 40m. Chicago and Medellín are separated by a distance of 2589 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Chicago to Medellín round-trip?

    According to our current data, JetBlue ($161), Copa Airlines ($287), and Avianca ($301) offers the cheapest pricing from Chicago to Medellín. These flights start at 65% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Chicago to Medellín one-way?

    The cheapest airlines for a one-way flight from Chicago to Medellín are Copa Airlines ($143), Avianca ($158), and American Airlines ($185).

  • What are the most popular routes from Chicago to Medellín?

  • Can I find deals for flights from Chicago to Medellín that include hotel bookings?

    Yes. In addition to deals on Chicago to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Medellín.

  • Can I find deals for business class flights from Chicago to Medellín?

    Yes. Cheapflights offers flight deals from Chicago to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Medellín?

    Currently, February is the cheapest month in which you can book a flight from Chicago to Medellín (average of $370). Flying from Chicago to Medellín in December is currently the most expensive (average of $663). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Chicago to Medellín

AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$161Average$661FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$287Average$498FlexibilityNo cancel feeOn-time70%
AviancaCheapest$301Average$506FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$319Average$587FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$427Average$645FlexibilityNo cancel feeOn-time71%
ArajetCheapest$450Average$585FlexibilityNo cancel feeOn-timeN/A

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