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$250+ Cheap flights from Charleston (CHS) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Aug 25 — Sep 11
Tue 8/25
Tue 9/1
1 adult, Economy
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Cheap flight deals from Charleston to Medellín

Cheapest flights from Charleston to Medellín
Explore the most affordable flight options available from Charleston to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.

This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:41 am
CHS
-
MDE
1 stop11h 53m
American Airlines
Wed 11/47:30 am
MDE
-
CHS
1 stop14h 32m
American Airlines
Deal found 7/25$389
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:35 pm
CHS
-
MDE
2 stops28h 55m
Delta
Tue 9/298:30 am
MDE
-
CHS
2 stops23h 18m
Delta
Deal found 7/22$406
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:31 pm
CHS
-
MDE
2 stops20h 17m
American Airlines
Tue 9/291:53 pm
MDE
-
CHS
2 stops18h 54m
American Airlines
Deal found 7/22$422
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:41 pm
CHS
-
MDE
2 stops18h 07m
American Airlines
Mon 9/286:00 am
MDE
-
CHS
2 stops15h 33m
American Airlines
Deal found 7/22$430
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:19 pm
CHS
-
MDE
2 stops9h 15m
American Airlines
Thu 11/123:12 pm
MDE
-
CHS
2 stops17h 19m
American Airlines
Deal found 7/25$431
This LATAM Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:50 am
CHS
-
MDE
2 stops14h 40m
LATAM Airlines
Tue 9/298:30 am
MDE
-
CHS
2 stops24h 38m
LATAM Airlines
Deal found 7/22$435
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:12 am
CHS
-
MDE
1 stop10h 03m
American Airlines
Tue 10/206:00 am
MDE
-
CHS
1 stop16h 59m
American Airlines
Deal found 7/24$457
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:26 pm
CHS
-
MDE
2 stops18h 46m
American Airlines
Sun 11/157:30 am
MDE
-
CHS
1 stop16h 29m
American Airlines
Deal found 7/24$468

Find flight deals from Charleston to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2026.

Round-trip from

$389
(American Airlines)

One-way from

$250
(Kiwi.com)

Popular in

April

Cheapest in

September

Average price

$863
From Charleston to Medellín
Search Deals
One-way flight from Charleston to Medellín
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($156 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Charleston to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sat 10/17

6:19 pm-4:40 pm

2 stops23h 21m

Medellín Jose Maria Cordova Intl

Sun 10/25

9:45 am-11:59 pm

2 stops13h 14m

$513

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 9/17

12:43 pm-10:35 pm

2 stops10h 52m

Medellín Jose Maria Cordova Intl

Mon 9/28

6:25 am-8:48 am

2 stops25h 23m

$513

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 11/11

6:30 am-10:05 pm

2 stops15h 35m

Medellín Jose Maria Cordova Intl

Sun 11/15

7:55 am-11:56 pm

2 stops16h 01m

$513
Quickest round-trip

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 8/26

1:01 pm-10:35 pm

2 stops10h 34m

Medellín Jose Maria Cordova Intl

Sun 8/30

7:50 am-11:59 pm

2 stops15h 09m

$537

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Tue 9/1

1:01 pm-10:35 pm

2 stops10h 34m

Medellín Jose Maria Cordova Intl

Mon 9/14

5:50 am-8:48 am

2 stops25h 58m

$537

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 8/16

6:00 am-8:15 pm

1 stop15h 15m

Medellín Jose Maria Cordova Intl

Fri 9/11

6:00 am-5:33 pm

1 stop10h 33m

$552

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sat 10/17

11:12 am-8:15 pm

1 stop10h 03m

Medellín Jose Maria Cordova Intl

Sun 10/25

6:00 am-11:57 pm

2 stops16h 57m

$582

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sat 9/19

6:30 pm-12:48 pm

1 stop19h 18m

Medellín Jose Maria Cordova Intl

Sat 9/26

6:00 am-11:43 pm

1 stop16h 43m

$584

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 11/11

7:00 am-9:15 pm

1 stop14h 15m

Medellín Jose Maria Cordova Intl

Sun 11/15

7:30 am-11:59 pm

1 stop16h 29m

$607
Cheapest one-way

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 8/12

7:48 pm-12:48 pm

2 stops18h 00m

$278

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Best time to book a flight from Charleston to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Medellín

What is the cheapest month to book a flight from Charleston to Medellín?

Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $285). Flying from Charleston to Medellín in April is currently the most expensive (average of $991). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated July 26, 2026.
Read through reviews of airlines operating flights from Charleston to Medellín, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,844 reviews

Food

6.4

Comfort

7.2

Boarding

7.5

Overall

7.1

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.1
Good
11,844 reviews
American Airlines
7.1
Good
11,844 reviews

Food

6.4

Comfort

7.2

Boarding

7.5

Overall

7.1

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

Find useful and relevant information for your journey from Charleston to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Medellín?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Medellín. You should not have trouble finding flights to Medellín from Charleston; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 1 airline has flights from the Charleston airport to Medellín. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • How long is the flight from Charleston to Medellín?

    There are many flights that can get you from Charleston to Medellín in 11h 53m. Fly via American Airlines or Delta to get the fastest option. The distance from Charleston to Medellín is about 1869 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Charleston to Medellín round-trip?

    American Airlines, at $523, was found to be the cheapest airline from Charleston to Medellín.. American Airlines is 21% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Medellín that include hotel bookings?

    Yes. In addition to deals on Charleston to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Medellín.

  • Can I find deals for business class flights from Charleston to Medellín?

    Yes. Cheapflights offers flight deals from Charleston to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Medellín?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $285). Flying from Charleston to Medellín in April is currently the most expensive (average of $991). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Charleston to Medellín

Discover the top airline that operate flights from Charleston to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$523Average$599FlexibilityNo cancel feeOn-time71%

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