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$163+ Cheap flights from Charleston (CHS) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Charleston to Medellín

Best flights from Charleston to Medellín
Discover carefully curated flight deals from Charleston to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/156:35 pmCHS - MDE
1 stop27h 05mMultiple Airlines
Mon 1/192:50 pmMDE - CHS
1 stop17h 48mMultiple Airlines
Deal found 12/21$424
This Expedia deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/32:00 pmCHS - MDE
1 stop24h 45mJetBlue
Wed 3/111:25 pmMDE - CHS
1 stop21h 18mJetBlue
Deal found 12/21$485
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:47 pmCHS - MDE
2 stops26h 18mUnited Airlines
Tue 3/109:45 amMDE - CHS
2 stops27h 07mUnited Airlines
Deal found 12/21$528
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:57 amCHS - MDE
1 stop10h 13mAmerican Airlines
Sat 3/712:20 amMDE - CHS
1 stop9h 06mAmerican Airlines
Deal found 12/22$543
This Avianca Connect deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:35 pmCHS - MDE
1 stop27h 05mMultiple Airlines
Fri 3/131:00 pmMDE - CHS
1 stop8h 37mMultiple Airlines
Deal found 12/21$427
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:35 pmCHS - MDE
1 stop19h 38mMultiple Airlines
Tue 3/109:50 pmMDE - CHS
2 stops33h 48mMultiple Airlines
Deal found 12/21$453
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:00 pmCHS - MDE
2 stops40h 00mMultiple Airlines
Thu 3/121:00 pmMDE - CHS
1 stop9h 26mMultiple Airlines
Deal found 12/21$475
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/203:01 pmCHS - MDE
1 stop24h 59mMultiple Airlines
Tue 1/279:50 pmMDE - CHS
2 stops34h 48mMultiple Airlines
Deal found 12/21$531
This oojo deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:00 pmCHS - MDE
1 stop7h 40mMultiple Airlines
Sun 3/81:00 pmMDE - CHS
1 stop23h 01mMultiple Airlines
Deal found 12/21$538

Find flight deals from Charleston to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 23, 2025.

Round-trip from

$391
(Kiwi.com)

One-way from

$163
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$1,804
From Charleston to Medellín
Search Deals
One-way flight from Charleston to Medellín
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($285 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 16% potential price decrease ($101 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Charleston to Medellín that are best for you.

Fly from

Charleston

Fly to

Medellín

Route

Depart

Return

Price

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 1/15

6:35 pm-9:40 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Mon 1/19

2:50 pm-8:38 am

1 stop17h 48m

$424

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 3/5

6:35 pm-9:40 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Fri 3/13

1:00 pm-10:37 pm

1 stop8h 37m

$427

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 3/2

6:35 pm-2:13 pm

1 stop19h 38m

Medellín Jose Maria Cordova Intl

Tue 3/10

9:50 pm-8:38 am

2 stops33h 48m

$453

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 3/4

5:00 pm-9:00 am

2 stops40h 00m

Medellín Jose Maria Cordova Intl

Thu 3/12

1:00 pm-11:26 pm

1 stop9h 26m

$475

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Tue 3/3

2:00 pm-2:45 pm

1 stop24h 45m

Medellín Jose Maria Cordova Intl

Wed 3/11

1:25 pm-11:43 am

1 stop21h 18m

$485

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 3/2

7:47 pm-10:05 pm

2 stops26h 18m

Medellín Jose Maria Cordova Intl

Tue 3/10

9:45 am-1:52 pm

2 stops27h 07m

$528

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Tue 1/20

3:01 pm-4:00 pm

1 stop24h 59m

Medellín Jose Maria Cordova Intl

Tue 1/27

9:50 pm-8:38 am

2 stops34h 48m

$531

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 2/26

2:00 pm-9:40 pm

1 stop7h 40m

Medellín Jose Maria Cordova Intl

Sun 3/8

1:00 pm-1:01 pm

1 stop23h 01m

$538

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 2/26

10:57 am-9:10 pm

1 stop10h 13m

Medellín Jose Maria Cordova Intl

Sat 3/7

12:20 am-9:26 am

1 stop9h 06m

$543

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 1/2

10:18 pm-2:14 pm

1 stop15h 56m

$163

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 11 results
1
2

Best time to book a flight from Charleston to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Medellín

What is the cheapest month to book a flight from Charleston to Medellín?

Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to MDE?

Find hourly flight availability from Charleston to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

It’s optimal to fly from Charleston to Medellín at noon. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 23, 2025.
Read through reviews of airlines operating flights from Charleston to Medellín, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,054 reviews

Entertainment

6.9

Crew

8.0

Overall

7.2

Food

6.4

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,054 reviews
American Airlines
7.2
Good
11,054 reviews

Entertainment

6.9

Crew

8.0

Overall

7.2

Food

6.4

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Charleston to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Medellín?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Medellín. You should not have trouble finding flights to Medellín from Charleston; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 1 airline has flights from the Charleston airport to Medellín. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • How long is the flight from Charleston to Medellín?

    There are many flights that can get you from Charleston to Medellín in 24h 45m. Fly via JetBlue to get the fastest option. The distance from Charleston to Medellín is about 1869 mi.

  • What is the cheapest airline to fly from Charleston to Medellín round-trip?

    American Airlines, at $501, was found to be the cheapest airline from Charleston to Medellín.. American Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Medellín that include hotel bookings?

    Yes. In addition to deals on Charleston to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Medellín.

  • Can I find deals for business class flights from Charleston to Medellín?

    Yes. Cheapflights offers flight deals from Charleston to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Medellín?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Charleston to Medellín

Discover the top airline that operate flights from Charleston to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$501Average$599FlexibilityNo cancel feeOn-time71%

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