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$125+ Cheap flights from Charleston (CHS) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Charleston to Medellín

Cheapest flights from Charleston to Medellín
Explore the most affordable flight options available from Charleston to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:18 pmCHS - MDE
1 stop23h 22mMultiple Airlines
Wed 12/312:25 amMDE - CHS
1 stop18h 58mMultiple Airlines
Deal found 12/26$515
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:18 pmCHS - MDE
1 stop23h 22mMultiple Airlines
Wed 12/312:25 amMDE - CHS
1 stop18h 58mMultiple Airlines
Deal found 12/26$539
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:59 pmCHS - MDE
1 stop19h 56mMultiple Airlines
Wed 12/312:25 amMDE - CHS
1 stop18h 58mMultiple Airlines
Deal found 12/26$598
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:09 pmCHS - MDE
2 stops28h 19mMultiple Airlines
Wed 1/72:54 pmMDE - CHS
1 stop17h 44mMultiple Airlines
Deal found 12/26$635
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:18 pmCHS - MDE
1 stop23h 22mMultiple Airlines
Wed 1/78:30 pmMDE - CHS
2 stops45h 06mMultiple Airlines
Deal found 12/26$657
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:59 pmCHS - MDE
1 stop19h 56mMultiple Airlines
Wed 1/72:54 pmMDE - CHS
1 stop17h 44mMultiple Airlines
Deal found 12/26$693
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:18 pmCHS - MDE
1 stop23h 22mMultiple Airlines
Wed 1/72:54 pmMDE - CHS
1 stop17h 44mMultiple Airlines
Deal found 12/26$708

Find flight deals from Charleston to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Round-trip from

$317
(Avianca Connect)

One-way from

$125
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$1,804
From Charleston to Medellín
Search Deals
One-way flight from Charleston to Medellín
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($285 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 16% potential price decrease ($101 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Charleston to Medellín that are best for you.

Fly from

Charleston

Fly to

Medellín

Route

Depart

Return

Price

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 2/23

6:35 pm-9:40 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Sun 3/1

1:00 pm-5:40 pm

1 stop28h 40m

$317

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 2/1

6:35 pm-9:40 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Thu 3/19

1:00 pm-11:26 pm

1 stop9h 26m

$336

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 1/29

6:35 pm-9:40 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Mon 2/2

6:55 am-5:36 pm

2 stops10h 41m

$363

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 1/29

6:35 pm-9:40 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Sun 2/1

6:25 am-5:36 pm

2 stops11h 11m

$416

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sat 2/21

6:35 pm-2:13 pm

1 stop19h 38m

Medellín Jose Maria Cordova Intl

Mon 2/23

6:55 am-5:40 pm

2 stops10h 45m

$418

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 3/4

5:00 pm-1:55 pm

2 stops20h 55m

Medellín Jose Maria Cordova Intl

Thu 3/12

1:00 pm-11:26 pm

1 stop9h 26m

$469

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 2/18

9:20 am-9:40 pm

1 stop12h 20m

Medellín Jose Maria Cordova Intl

Tue 2/24

1:00 pm-1:54 pm

1 stop24h 54m

$496

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 2/2

6:35 pm-3:23 pm

2 stops44h 48m

$125

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 2/1

6:35 pm-9:40 pm

1 stop27h 05m

$145

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 2/1

1:35 pm-1:20 pm

2 stops23h 45m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 16 results
1
2

Best time to book a flight from Charleston to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Medellín

What is the cheapest month to book a flight from Charleston to Medellín?

Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to MDE?

Find hourly flight availability from Charleston to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

It’s optimal to fly from Charleston to Medellín at noon. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 28, 2025.
Read through reviews of airlines operating flights from Charleston to Medellín, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,072 reviews

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.5

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,072 reviews
American Airlines
7.2
Good
11,072 reviews

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.5

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Charleston to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Medellín?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Medellín. You should not have trouble finding flights to Medellín from Charleston; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 1 airline has flights from the Charleston airport to Medellín. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • What is the cheapest airline to fly from Charleston to Medellín round-trip?

    American Airlines, at $501, was found to be the cheapest airline from Charleston to Medellín.. American Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Medellín that include hotel bookings?

    Yes. In addition to deals on Charleston to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Medellín.

  • Can I find deals for business class flights from Charleston to Medellín?

    Yes. Cheapflights offers flight deals from Charleston to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Medellín?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Medellín

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Top airline flying from Charleston to Medellín

Discover the top airline that operate flights from Charleston to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$501Average$599FlexibilityNo cancel feeOn-time71%

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