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$221+ Cheap flights from Charleston (CHS) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
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Cheap flight deals from Charleston to Medellín

Cheapest flights from Charleston to Medellín
Explore the most affordable flight options available from Charleston to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This Avianca Connect deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:07 am
CHS
-
MDE
1 stop14h 18m
Multiple Airlines
Wed 4/151:00 pm
MDE
-
CHS
1 stop7h 49m
Multiple Airlines
Deal found 2/15$357
This SmartFares deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:08 pm
CHS
-
MDE
1 stop19h 02m
JetBlue
Tue 5/191:20 pm
MDE
-
CHS
1 stop28h 53m
JetBlue
Deal found 2/16$420
This Avianca deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:00 am
CHS
-
MDE
2 stops13h 35m
Multiple Airlines
Tue 5/198:00 pm
MDE
-
CHS
1 stop13h 15m
Multiple Airlines
Deal found 2/16$487
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
CHS
-
MDE
2 stops16h 10m
United Airlines
Tue 6/99:45 am
MDE
-
CHS
2 stops23h 38m
United Airlines
Deal found 2/17$566
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:52 am
CHS
-
MDE
2 stops13h 58m
American Airlines
Tue 6/91:53 pm
MDE
-
CHS
1 stop9h 02m
American Airlines
Deal found 2/17$576

Find flight deals from Charleston to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 18, 2026.

Round-trip from

$357
(Avianca Connect)

One-way from

$221
(Kiwi.com)

Popular in

May

Cheapest in

September

Average price

$608
From Charleston to Medellín
Search Deals
One-way flight from Charleston to Medellín
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Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in February 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Charleston to Medellín that are best for you.

Fly from

Charleston

Fly to

Medellín

Route

Depart

Return

Price

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 4/8

8:07 am-9:25 pm

1 stop14h 18m

Medellín Jose Maria Cordova Intl

Wed 4/15

1:00 pm-9:49 pm

1 stop7h 49m

$357

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 5/13

8:08 pm-2:10 pm

1 stop19h 02m

Medellín Jose Maria Cordova Intl

Tue 5/19

1:20 pm-7:13 pm

1 stop28h 53m

$420

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 5/13

11:00 am-11:35 pm

2 stops13h 35m

Medellín Jose Maria Cordova Intl

Tue 5/19

8:00 pm-10:15 am

1 stop13h 15m

$487

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 2/26

5:00 pm-7:40 pm

2 stops26h 40m

$221

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 2/25

5:00 pm-8:18 am

3 stops39h 18m

$277

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 2/26

6:35 pm-2:13 pm

1 stop19h 38m

$296

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 4/3

8:28 pm-10:55 am

2 stops15h 27m

$316

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 2/25

2:50 pm-2:45 pm

1 stop23h 55m

$323

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 4/3

8:08 pm-1:10 pm

1 stop18h 02m

$473

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Best time to book a flight from Charleston to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Medellín

What is the cheapest month to book a flight from Charleston to Medellín?

Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $618). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Charleston to Medellín?

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated February 18, 2026.
Read through reviews of airlines operating flights from Charleston to Medellín, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,304 reviews

Food

6.4

Overall

7.2

Boarding

7.5

Crew

8.0

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,304 reviews
American Airlines
7.2
Good
11,304 reviews

Food

6.4

Overall

7.2

Boarding

7.5

Crew

8.0

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Medellín?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Medellín. You should not have trouble finding flights to Medellín from Charleston; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 1 airline has flights from the Charleston airport to Medellín. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • How long is the flight from Charleston to Medellín?

    There are many flights that can get you from Charleston to Medellín in 19h 02m. Fly via JetBlue to get the fastest option. The distance from Charleston to Medellín is about 1869 mi.

  • What is the cheapest airline to fly from Charleston to Medellín round-trip?

    American Airlines, at $523, was found to be the cheapest airline from Charleston to Medellín.. American Airlines is 12% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Medellín that include hotel bookings?

    Yes. In addition to deals on Charleston to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Medellín.

  • Can I find deals for business class flights from Charleston to Medellín?

    Yes. Cheapflights offers flight deals from Charleston to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Medellín?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $618). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Charleston to Medellín

Discover the top airline that operate flights from Charleston to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$523Average$578FlexibilityNo cancel feeOn-time71%

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