$174+ Cheap flights from Charleston (CHS) to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Medellín with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Medellín
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Best
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Cheapest flights from Charleston to MedellínExplore the most affordable flight options available from Charleston to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Charleston to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
1 stop15h 10m
Sun 10/259:45 am -
2 stops23h 21m
Deal found 8/25![United Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:50 pm -
2 stops27h 20m
Mon 10/269:45 am -
1 stop11h 14m
Deal found 8/25![United Airlines logo]()
$452
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:05 pm -
1 stop29h 10m
Wed 11/410:40 am -
1 stop11h 19m
Deal found 8/21![United Airlines logo]()
$517
This LATAM Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:50 am -
2 stops14h 15m
Fri 10/237:50 am -
2 stops15h 09m
Deal found 8/23![LATAM Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
1 stop15h 10m
Fri 10/239:45 am -
1 stop11h 36m
Deal found 8/26![United Airlines logo]()
$548
This oojo deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:52 pm -
2 stops28h 43m
Tue 9/298:30 am -
2 stops23h 18m
Deal found 8/21![LATAM Airlines logo]()
$549
This Avianca deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:19 pm -
2 stops12h 41m
Sun 11/158:10 pm -
1 stop13h 49m
Deal found 8/25![Multiple Airlines logo]()
$567
Best flights from Charleston to MedellínDiscover carefully curated flight deals from Charleston to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Charleston to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
1 stop15h 10m
Sun 10/259:45 am -
2 stops23h 21m
Deal found 8/21![United Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:58 pm -
2 stops29h 12m
Mon 10/269:45 am -
2 stops24h 34m
Deal found 8/25![United Airlines logo]()
$392
Last-minute flights from Charleston to MedellínDiscover last-minute flight deals from Charleston to Medellín. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Medellín. Data last updated August 26, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:30 am -
2 stops15h 40m
Sat 8/299:45 am -
2 stops23h 51m
Deal found 8/23![United Airlines logo]()
$657
This oojo deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:25 am -
2 stops12h 10m
Mon 8/3111:15 pm -
2 stops17h 36m
Deal found 8/24![LATAM Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
2 stops15h 15m
Sun 9/276:00 am -
1 stop16h 43m
Deal found 8/25![American Airlines logo]()
$782
This oojo deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:52 pm -
2 stops28h 43m
Tue 9/298:30 am -
2 stops23h 18m
Deal found 8/21![LATAM Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:30 am -
2 stops39h 40m
Fri 9/259:45 am -
2 stops23h 42m
Deal found 8/25![United Airlines logo]()
$567
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:30 am -
2 stops39h 40m
Tue 9/299:45 am -
2 stops23h 42m
Deal found 8/24![United Airlines logo]()
$623
This FlightHub deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:25 pm -
1 stop27h 00m
Tue 9/298:00 pm -
1 stop13h 17m
Deal found 8/21![Multiple Airlines logo]()
$694
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop26h 55m
Fri 9/256:00 am -
1 stop16h 43m
Deal found 8/25![American Airlines logo]()
$751
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop19h 28m
Tue 9/296:00 am -
2 stops14h 06m
Deal found 8/24![American Airlines logo]()
$758
One-way flights from Charleston to MedellínSearch for one-way flight options from Charleston to Medellín. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Charleston to Medellín. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:58 pm -
2 stops29h 12m
Deal found 8/24![United Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:13 pm -
3 stops43h 02m
Deal found 8/25![Multiple Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:51 pm -
2 stops26h 19m
Deal found 8/25![United Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
2 stops15h 35m
Deal found 8/25![Delta logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:27 pm -
3 stops19h 13m
Deal found 8/24![Multiple Airlines logo]()
$284
This FlightHub deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:33 pm -
1 stop15h 47m
Deal found 8/26![Multiple Airlines logo]()
$305
This BusinessClass deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:54 pm -
3 stops22h 56m
Deal found 8/25![Avianca logo]()
$586
Find flight deals from Charleston to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 26, 2026.
Round-trip from | $392 (United Airlines) |
|---|---|
One-way from | $174 (United Airlines) |
Popular in | April |
Cheapest in | March |
Average price | $723 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Charleston to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Sat 10/17
7:00 am-9:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Sun 10/25
9:45 am-10:06 am
2 stops23h 21m
$392
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Thu 10/22
4:58 pm-9:10 pm
2 stops29h 12m
Medellín Jose Maria Cordova Intl
Mon 10/26
9:45 am-11:19 am
2 stops24h 34m
$392
Cheapest one-way
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Thu 9/17
2:13 pm-8:15 am
2 stops43h 02m
$225
Quickest one-way
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Mon 9/21
7:00 am-9:10 pm
1 stop15h 10m
$228
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Mon 10/19
6:30 am-9:10 pm
2 stops15h 40m
$228
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Mon 10/19
5:30 am-9:05 pm
2 stops16h 35m
$272
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Mon 9/21
3:27 pm-9:40 am
3 stops19h 13m
$284
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Mon 10/19
8:33 pm-11:20 am
1 stop15h 47m
$305
Sorted by cheapest first
Best time to book a flight from Charleston to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from Charleston with our price prediction graph.
CHS-CO1
CHS-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Medellín
CHS-CO1
CHS-MDE
What is the cheapest month to book a flight from Charleston to Medellín?
Currently, March is the cheapest month in which you can book a flight from Charleston to Medellín (average of $523). Flying from Charleston to Medellín in April is currently the most expensive (average of $991). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated August 26, 2026.
Read through reviews of airlines operating flights from Charleston to Medellín, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Overall
7.1
Food
6.4
Comfort
7.2
Entertainment
6.8
Boarding
7.5
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Crew
7.9
Overall
7.1
Food
6.4
Comfort
7.2
Entertainment
6.8
Boarding
7.5
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Charleston to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Charleston to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Medellín flights
Browse other Charleston and Medellín flight options. Last updated on August 26, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Charleston to Medellín
Discover the top airline that operate flights from Charleston to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$523 | Average$599 | FlexibilityNo cancel fee | On-time71% |