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$165+ Cheap flights from Charleston (CHS) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
May 21 — May 281
Thu 5/21
Thu 5/28
1 adult, Economy
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Cheap flight deals from Charleston to Medellín

Cheapest flights from Charleston to Medellín
Explore the most affordable flight options available from Charleston to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:44 pm
CHS
-
MDE
1 stop22h 16m
Multiple Airlines
Tue 5/261:55 pm
MDE
-
CHS
1 stop18h 43m
Multiple Airlines
Deal found 4/17$413
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:44 pm
CHS
-
MDE
1 stop22h 16m
Multiple Airlines
Mon 5/251:55 pm
MDE
-
CHS
1 stop17h 43m
Multiple Airlines
Deal found 4/17$430
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:34 pm
CHS
-
MDE
1 stop21h 26m
Multiple Airlines
Wed 6/101:55 pm
MDE
-
CHS
1 stop17h 43m
Multiple Airlines
Deal found 4/18$454
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:23 pm
CHS
-
MDE
1 stop22h 37m
Multiple Airlines
Tue 5/261:55 pm
MDE
-
CHS
1 stop18h 43m
Multiple Airlines
Deal found 4/17$457
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:23 pm
CHS
-
MDE
1 stop22h 37m
Multiple Airlines
Mon 5/251:55 pm
MDE
-
CHS
1 stop17h 43m
Multiple Airlines
Deal found 4/17$474
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:20 pm
CHS
-
MDE
2 stops36h 55m
Multiple Airlines
Tue 5/261:55 pm
MDE
-
CHS
1 stop18h 43m
Multiple Airlines
Deal found 4/17$499
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/264:34 pm
CHS
-
MDE
1 stop24h 11m
Multiple Airlines
Sun 8/307:05 am
MDE
-
CHS
2 stops24h 40m
Multiple Airlines
Deal found 4/17$508

Find flight deals from Charleston to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 21, 2026.

Round-trip from

$413
(Kiwi.com)

One-way from

$165
(Kiwi.com)

Popular in

July

Cheapest in

September

Average price

$523
From Charleston to Medellín
Search Deals
One-way flight from Charleston to Medellín
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($134 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Charleston to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 5/15

3:23 pm-1:00 pm

1 stop22h 37m

Medellín Jose Maria Cordova Intl

Mon 5/25

1:55 pm-8:38 am

1 stop17h 43m

$474

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 5/7

5:59 pm-2:02 pm

2 stops21h 03m

Medellín Jose Maria Cordova Intl

Tue 5/19

8:00 pm-10:28 am

1 stop13h 28m

$618

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 5/7

8:12 pm-2:02 pm

1 stop18h 50m

Medellín Jose Maria Cordova Intl

Tue 5/19

1:25 pm-10:28 am

2 stops20h 03m

$630

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 6/1

12:10 pm-11:50 pm

2 stops12h 40m

Medellín Jose Maria Cordova Intl

Mon 6/8

6:00 am-11:59 pm

2 stops16h 59m

$632

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 5/7

5:59 pm-9:10 am

1 stop16h 11m

Medellín Jose Maria Cordova Intl

Mon 5/18

1:00 pm-7:17 pm

1 stop29h 17m

$634
Quickest round-trip

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 8/26

6:00 am-12:48 pm

1 stop7h 48m

Medellín Jose Maria Cordova Intl

Sat 8/29

12:30 am-4:25 pm

1 stop14h 55m

$658

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 5/29

7:15 am-9:10 pm

1 stop14h 55m

Medellín Jose Maria Cordova Intl

Tue 6/2

9:45 am-10:16 am

2 stops23h 31m

$670

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 7/3

8:11 pm-12:51 pm

1 stop17h 40m

Medellín Jose Maria Cordova Intl

Sun 7/5

12:30 am-1:03 pm

2 stops11h 33m

$673
Cheapest one-way

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 5/27

4:34 pm-8:15 am

2 stops40h 41m

$196

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sat 5/9

3:44 pm-12:43 pm

2 stops21h 59m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/19

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Charleston to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Medellín

What is the cheapest month to book a flight from Charleston to Medellín?

Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $156). Flying from Charleston to Medellín in May is currently the most expensive (average of $795). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Charleston to Medellín?

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated April 21, 2026.
Read through reviews of airlines operating flights from Charleston to Medellín, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,644 reviews

Crew

7.9

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,644 reviews
American Airlines
7.1
Good
11,644 reviews

Crew

7.9

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Medellín?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Medellín. You should not have trouble finding flights to Medellín from Charleston; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 1 airline has flights from the Charleston airport to Medellín. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • What is the cheapest airline to fly from Charleston to Medellín round-trip?

    American Airlines, at $523, was found to be the cheapest airline from Charleston to Medellín.. American Airlines is 14% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Medellín that include hotel bookings?

    Yes. In addition to deals on Charleston to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Medellín.

  • Can I find deals for business class flights from Charleston to Medellín?

    Yes. Cheapflights offers flight deals from Charleston to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Medellín?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $156). Flying from Charleston to Medellín in May is currently the most expensive (average of $795). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Charleston to Medellín

Discover the top airline that operate flights from Charleston to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$523Average$599FlexibilityNo cancel feeOn-time71%

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