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$127+ Cheap flights from Charleston (CHS) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from Charleston to Medellín

Cheapest flights from Charleston to Medellín
Explore the most affordable flight options available from Charleston to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:50 amCHS - MDE
1 stop18h 06mMultiple Airlines
Fri 12/52:05 amMDE - CHS
2 stops20h 54mMultiple Airlines
Deal found 11/19$423
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:50 amCHS - MDE
1 stop7h 13mSpirit Airlines
Sat 12/62:54 pmMDE - CHS
2 stops30h 00mSpirit Airlines
Deal found 11/19$438
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:25 amCHS - MDE
2 stops28h 30mMultiple Airlines
Sat 12/272:54 pmMDE - CHS
1 stop17h 43mMultiple Airlines
Deal found 11/20$508
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:50 amCHS - MDE
2 stops16h 38mMultiple Airlines
Mon 12/11:51 amMDE - CHS
2 stops29h 35mMultiple Airlines
Deal found 11/20$519

Cheap flight deals from Charleston to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Round-trip from

$294
(KAYAK)

One-way from

$127
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$553
From Charleston to Medellín
Search Deals
One-way flight from Charleston to Medellín
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Highest demand for flights based on searches. 10% potential increase in price ($74 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Charleston to Medellín that are best for you.

Fly from

Charleston

Fly to

Medellín

Route

Depart

Return

Price

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 11/28

6:50 am-12:56 am

1 stop18h 06m

Medellín Jose Maria Cordova Intl

Fri 12/5

2:05 am-10:59 pm

2 stops20h 54m

$423

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 11/28

6:50 am-2:03 pm

1 stop7h 13m

Medellín Jose Maria Cordova Intl

Sat 12/6

2:54 pm-8:54 pm

2 stops30h 00m

$438

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 12/1

6:50 am-11:28 pm

2 stops16h 38m

Medellín Jose Maria Cordova Intl

Mon 12/1

1:51 am-7:26 am

2 stops29h 35m

$519

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 12/21

10:18 pm-1:28 am

1 stop27h 10m

Medellín Jose Maria Cordova Intl

Sat 12/27

2:25 am-9:23 pm

1 stop18h 58m

$573

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 2/2

6:30 am-10:05 pm

1 stop15h 35m

Medellín Jose Maria Cordova Intl

Fri 2/6

10:45 am-9:57 pm

1 stop11h 12m

$594

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 12/29

10:18 pm-1:57 pm

2 stops15h 39m

$133

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 1/8

6:31 pm-9:40 pm

1 stop27h 09m

$152

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 1/9

6:31 pm-9:40 pm

1 stop27h 09m

$153

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 1/5

10:18 pm-2:14 pm

1 stop15h 56m

$156

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 1/4

10:18 pm-1:28 am

1 stop27h 10m

$162

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 15 results
1
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Best time to book a flight from Charleston to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Medellín

What is the cheapest month to book a flight from Charleston to Medellín?

Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to MDE?

Find hourly flight availability from Charleston to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

It’s optimal to fly from Charleston to Medellín at noon. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated November 20, 2025.
Read through reviews of airlines operating flights from Charleston to Medellín, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,047 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.
American Airlines
7.2
Good
11,047 reviews
American Airlines
7.2
Good
11,047 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Medellín?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Medellín. You should not have trouble finding flights to Medellín from Charleston; the airport handles an average of 0 outbound flights to Medellín per day. You should also have plenty of airline options to choose from since 1 airline has flights from the Charleston airport to Medellín. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • How long is the flight from Charleston to Medellín?

    There are many flights that can get you from Charleston to Medellín in 7h 13m. Fly via Spirit Airlines to get the fastest option. The distance from Charleston to Medellín is about 1869 mi.

  • What is the cheapest airline to fly from Charleston to Medellín round-trip?

    American Airlines, at $471, was found to be the cheapest airline from Charleston to Medellín.. American Airlines is 25% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Charleston to Medellín that include hotel bookings?

    Yes. In addition to deals on Charleston to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Medellín.

  • Can I find deals for business class flights from Charleston to Medellín?

    Yes. Cheapflights offers flight deals from Charleston to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Medellín?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Medellín (average of $176). Flying from Charleston to Medellín in June is currently the most expensive (average of $608). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Charleston to Medellín

Discover the top airline that operate flights from Charleston to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$471Average$634FlexibilityNo cancel feeOn-time71%

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