How popular is this Missouri to Massachusetts flight route?

This flight path from Missouri to Massachusetts was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Missouri to Massachusetts?

There are many flights that can get you from Missouri to Massachusetts in 5h 12m. Fly via Frontier, United Airlines, or American Airlines to get the fastest option. The distance from Missouri to Massachusetts is about 1234 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Massachusetts ranges from 3.1 - 4.0 inches per month. March is typically the wettest month, when rainfall can reach 4.0 in. July is typically the driest time to visit Massachusetts when rainfall is around 3.1 in.

If weather is an important factor for your trip to Massachusetts, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?

Yes. In addition to deals on Missouri to Massachusetts flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Massachusetts?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Massachusetts.

Can I find deals for business class flights from Missouri to Massachusetts?

Yes. Cheapflights offers flight deals from Missouri to Massachusetts by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$63+ Flights from Missouri to Massachusetts

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheap flight deals from Missouri to Massachusetts

Cheapest flights from Missouri to Massachusetts
Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/244:12 pmMCI - ALB

1 stop5h 01mDelta

Thu 12/255:15 pmALB - MCI

1 stop4h 50mDelta

Deal found 12/17

$281

Fri 12/198:37 pmSTL - BOS

1 stop12h 44mFrontier

Thu 1/811:06 amBOS - STL

1 stop12h 27mFrontier

Deal found 12/16

$282

Wed 12/312:50 pmSTL - BOS

Nonstop2h 39mAmerican Airlines

Tue 1/612:55 pmBOS - STL

1 stop9h 20mAmerican Airlines

Deal found 12/16

$288

Fri 12/198:37 pmSTL - BOS

1 stop12h 44mFrontier

Mon 1/1211:41 amBOS - STL

1 stop11h 52mFrontier

Deal found 12/16

$303

Fri 12/198:37 pmSTL - BOS

1 stop12h 44mFrontier

Sun 1/116:00 amBOS - STL

1 stop9h 48mFrontier

Deal found 12/16

$317

Sat 12/206:15 pmMCI - BOS

1 stop15h 35mSpirit Airlines

Wed 1/75:45 amBOS - MCI

1 stop12h 25mSpirit Airlines

Deal found 12/17

$330

Tue 12/3010:48 amSTL - BOS

2 stops23h 02mMultiple Airlines

Tue 1/612:29 pmBOS - STL

1 stop11h 04mMultiple Airlines

Deal found 12/17

$338

Wed 12/314:27 pmSTL - BOS

2 stops31h 52mMultiple Airlines

Tue 1/612:29 pmBOS - STL

1 stop11h 04mMultiple Airlines

Deal found 12/17

$346

Fri 12/266:24 pmSGF - BDL

1 stop4h 54mAmerican Airlines

Mon 1/57:50 amBDL - SGF

1 stop8h 04mAmerican Airlines

Deal found 12/16

$354

Wed 12/243:19 pmMCI - ALB

1 stop4h 46mUnited Airlines

Thu 12/255:45 amALB - MCI

2 stops9h 53mUnited Airlines

Deal found 12/17

$366

Tue 12/3010:48 amSTL - BOS

2 stops23h 02mMultiple Airlines

Sat 1/311:37 amBOS - STL

1 stop23h 03mMultiple Airlines

Deal found 12/17

$366

Wed 12/243:10 pmSTL - BDL

1 stop5h 25mUnited Airlines

Sun 1/46:15 pmBDL - STL

1 stop5h 28mUnited Airlines

Deal found 12/17

$368

Best flights from Missouri to Massachusetts
Discover carefully curated flight deals from Missouri to Massachusetts that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Wed 2/253:49 pmSTL - BOS

1 stop18h 59mMultiple Airlines

Tue 3/36:00 amBOS - STL

1 stop25h 51mMultiple Airlines

Deal found 12/17

$154

Wed 1/215:42 pmSTL - BDL

1 stop24h 54mFrontier

Sun 1/258:31 pmBDL - STL

1 stop13h 50mFrontier

Deal found 12/15

$166

Tue 2/101:28 pmSGF - BOS

1 stop9h 18mUnited Airlines

Wed 2/119:30 amBOS - SGF

1 stop6h 08mUnited Airlines

Deal found 12/14

$251

Tue 2/105:39 pmSGF - BOS

1 stop5h 12mAmerican Airlines

Wed 2/116:39 amBOS - SGF

1 stop6h 36mAmerican Airlines

Deal found 12/17

$251

Tue 1/202:15 pmSTL - ALB

2 stops6h 50mSouthwest

Tue 1/271:00 pmALB - STL

2 stops7h 00mSouthwest

Deal found 12/15

$287

Fri 1/235:00 pmSGF - BOS

1 stop7h 04mDelta

Mon 1/2611:12 amBOS - SGF

1 stop6h 03mDelta

Deal found 12/16

$289

Tue 4/711:26 amMCI - BOS

1 stop11h 41mSpirit Airlines

Fri 4/105:39 pmBOS - MCI

1 stop17h 44mSpirit Airlines

Deal found 12/17

$338

Wed 1/215:42 pmSTL - BDL

2 stops29h 14mMultiple Airlines

Sun 1/258:31 pmBDL - STL

1 stop13h 50mMultiple Airlines

Deal found 12/15

$180

Sun 2/13:59 pmMCI - BOS

1 stop22h 21mAlaska Airlines

Sun 2/85:20 pmBOS - MCI

1 stop22h 45mAlaska Airlines

Deal found 12/17

$423

Wed 2/253:49 pmSTL - BOS

1 stop18h 59mMultiple Airlines

Sun 3/14:22 pmBOS - STL

2 stops15h 29mMultiple Airlines

Deal found 12/17

$212

Sun 2/19:09 amSTL - BDL

1 stop9h 27mFrontier

Sat 2/78:01 pmBDL - STL

1 stop13h 03mFrontier

Deal found 12/17

$245

Tue 1/206:30 amSTL - ALB

1 stop7h 01mUnited Airlines

Tue 1/2710:05 amALB - STL

1 stop5h 25mUnited Airlines

Deal found 12/15

$256

Tue 1/206:00 amSTL - ALB

1 stop4h 41mAmerican Airlines

Tue 1/275:00 amALB - STL

1 stop5h 24mAmerican Airlines

Deal found 12/17

$256

Fri 1/238:22 pmSTL - BOS

2 stops17h 16mMultiple Airlines

Sun 1/253:43 pmBOS - STL

1 stop18h 38mMultiple Airlines

Deal found 12/17

$221

Thu 1/158:00 amSGF - BOS

1 stop8h 21mAmerican Airlines

Sun 1/181:48 pmBOS - SGF

1 stop8h 12mAmerican Airlines

Deal found 12/17

$257

Wed 2/48:10 amCOU - ALB

1 stop6h 11mUnited Airlines

Sat 2/76:00 amALB - COU

1 stop5h 42mUnited Airlines

Deal found 12/16

$268

Sat 1/178:45 amSTL - BOS

Nonstop2h 35mSouthwest

Sun 1/186:25 amBOS - STL

Nonstop3h 20mSouthwest

Deal found 12/17

$297

Wed 1/145:04 pmMCI - BDL

1 stop23h 07mMultiple Airlines

Wed 1/218:05 amBDL - MCI

2 stops51h 26mMultiple Airlines

Deal found 12/17

$230

Thu 1/15:42 pmMCI - BDL

1 stop4h 32mDelta

Tue 1/67:20 amBDL - MCI

1 stop8h 35mDelta

Deal found 12/16

$307

Thu 1/83:10 pmCOU - ALB

1 stop5h 12mUnited Airlines

Tue 1/134:20 pmALB - COU

1 stop6h 17mUnited Airlines

Deal found 12/17

$268

Fri 2/276:00 pmSGF - BOS

1 stop4h 59mAmerican Airlines

Tue 3/35:25 amBOS - SGF

1 stop9h 24mAmerican Airlines

Deal found 12/15

$270

Sat 1/1710:19 amSTL - BOS

1 stop4h 38mDelta

Sun 1/1811:00 amBOS - STL

1 stop6h 39mDelta

Deal found 12/17

$317

Sun 2/15:42 pmSTL - BDL

2 stops28h 34mMultiple Airlines

Sat 2/73:59 pmBDL - STL

1 stop8h 34mMultiple Airlines

Deal found 12/17

$239

Tue 1/205:55 pmSTL - BOS

Nonstop2h 30mSouthwest

Wed 1/216:25 amBOS - STL

Nonstop3h 20mSouthwest

Deal found 12/17

$324

Thu 1/83:10 pmCOU - ALB

1 stop5h 12mUnited Airlines

Sun 1/116:00 amALB - COU

1 stop5h 42mUnited Airlines

Deal found 12/17

$268

Sat 5/27:00 amMCI - BOS

3 stops23h 57mSpirit Airlines

Tue 5/57:00 amBOS - MCI

3 stops29h 07mSpirit Airlines

Deal found 12/16

$366

Fri 2/65:42 pmSTL - BDL

1 stop24h 24mMultiple Airlines

Mon 2/91:56 pmBDL - STL

2 stops10h 37mMultiple Airlines

Deal found 12/16

$240

Wed 1/141:28 pmSGF - BOS

1 stop9h 18mUnited Airlines

Thu 1/224:16 pmBOS - SGF

1 stop6h 42mUnited Airlines

Deal found 12/15

$270

Sat 1/3111:23 amSTL - BDL

1 stop7h 46mDelta

Mon 2/24:55 pmBDL - STL

1 stop4h 48mDelta

Deal found 12/17

$334

Thu 1/15:00 amSTL - BOS

1 stop5h 06mAmerican Airlines

Thu 1/89:51 amBOS - STL

1 stop9h 23mAmerican Airlines

Deal found 12/16

$307

Last-minute flights from Missouri to Massachusetts
Discover last-minute flight deals from Missouri to Massachusetts. Data last updated December 18, 2025 and is based on user searches.

Tue 1/66:15 pmMCI - BOS

1 stop15h 35mSpirit Airlines

Thu 1/85:27 pmBOS - MCI

1 stop18h 04mSpirit Airlines

Deal found 12/16

$163

Wed 1/73:47 pmMCI - BOS

1 stop17h 24mMultiple Airlines

Thu 1/85:27 pmBOS - MCI

1 stop18h 04mMultiple Airlines

Deal found 12/16

$178

Thu 1/83:43 pmSTL - BOS

1 stop8h 36mFrontier

Mon 1/1211:41 amBOS - STL

1 stop11h 52mFrontier

Deal found 12/16

$182

Sun 1/115:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Tue 1/136:00 amBOS - STL

1 stop25h 51mMultiple Airlines

Deal found 12/17

$172

Tue 1/135:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Fri 1/163:43 pmBOS - STL

1 stop7h 51mMultiple Airlines

Deal found 12/17

$143

Wed 1/148:32 pmSTL - BOS

2 stops18h 47mMultiple Airlines

Wed 1/213:43 pmBOS - STL

1 stop8h 50mMultiple Airlines

Deal found 12/17

$159

Wed 1/145:04 pmMCI - BOS

1 stop29h 15mSpirit Airlines

Wed 1/215:34 amBOS - MCI

1 stop29h 57mSpirit Airlines

Deal found 12/17

$177

Thu 1/1511:26 amMCI - BOS

1 stop11h 31mMultiple Airlines

Sun 1/188:47 amBOS - MCI

2 stops34h 31mMultiple Airlines

Deal found 12/16

$185

Fri 1/168:32 pmSTL - BOS

1 stop27h 41mMultiple Airlines

Fri 1/233:43 pmBOS - STL

1 stop8h 50mMultiple Airlines

Deal found 12/16

$170

Wed 1/218:22 pmSTL - BOS

1 stop27h 51mFrontier

Tue 1/276:00 amBOS - STL

1 stop25h 51mFrontier

Deal found 12/17

$142

Wed 1/215:42 pmSTL - BDL

1 stop24h 54mFrontier

Sun 1/258:31 pmBDL - STL

1 stop13h 50mFrontier

Deal found 12/15

$166

Wed 1/215:42 pmSTL - BDL

2 stops29h 14mMultiple Airlines

Sun 1/258:31 pmBDL - STL

1 stop13h 50mMultiple Airlines

Deal found 12/15

$180

One-way flights from Missouri to Massachusetts
Search for one-way flight options from Missouri to Massachusetts. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Sun 1/115:11 pmSTL - BDL

1 stop25h 13mFrontier

Deal found 12/15

$63

Mon 1/1211:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/17

$67

Mon 1/2611:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/15

$68

Sat 1/318:22 pmSTL - BOS

1 stop27h 51mFrontier

Deal found 12/17

$68

Tue 1/135:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Deal found 12/16

$69

Tue 1/66:15 pmMCI - BOS

1 stop15h 35mSpirit Airlines

Deal found 12/16

$78

Mon 1/125:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Deal found 12/17

$79

Sun 2/15:42 pmSTL - BOS

1 stop28h 37mMultiple Airlines

Deal found 12/16

$81

Thu 1/2911:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/17

$84

Sun 1/2511:26 amMCI - BOS

1 stop28h 02mSpirit Airlines

Deal found 12/17

$85

Mon 1/198:32 pmSTL - BOS

2 stops26h 25mMultiple Airlines

Deal found 12/16

$85

Thu 1/811:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/16

$90

Find flight deals from Missouri to Massachusetts

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$134 (Kiwi.com)
One-way from	$63 (Trip.com)
Popular in	November
Cheapest in	September
Average price	$427
Good round-trip deal	$479 or less
Good one-way deal	$315 or less

Provider with most accurate pricing for Lambert-St Louis-Boston Logan Intl flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Boston Logan Intl flights.

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From Missouri to Massachusetts

Search Deals

One-way flight from Missouri to Massachusetts

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($21 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Missouri to Massachusetts.

Search Deals

Price to beat on a one-way flight from Missouri to Massachusetts.

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Massachusetts that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Wed 2/25

3:49 pm-11:48 am

1 stop18h 59m

Boston Logan Intl

Tue 3/3

6:00 am-6:51 am

1 stop25h 51m

$154

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Wed 1/21

5:42 pm-7:36 pm

1 stop24h 54m

Hartford Bradley Intl

Sun 1/25

8:31 pm-9:21 am

1 stop13h 50m

$166

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Wed 1/21

5:42 pm-11:56 pm

2 stops29h 14m

Hartford Bradley Intl

Sun 1/25

8:31 pm-9:21 am

1 stop13h 50m

$180

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Wed 2/25

3:49 pm-11:48 am

1 stop18h 59m

Boston Logan Intl

Sun 3/1

4:22 pm-6:51 am

2 stops15h 29m

$212

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Fri 1/23

8:22 pm-2:38 pm

2 stops17h 16m

Boston Logan Intl

Sun 1/25

3:43 pm-9:21 am

1 stop18h 38m

$221

Kansas CityHartford

MCI - BDL

MCIBDL

Kansas City

Wed 1/14

5:04 pm-5:11 pm

1 stop23h 07m

Hartford Bradley Intl

Wed 1/21

8:05 am-10:31 am

2 stops51h 26m

$230

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Sun 2/1

5:42 pm-11:16 pm

2 stops28h 34m

Hartford Bradley Intl

Sat 2/7

3:59 pm-11:33 pm

1 stop8h 34m

$239

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Fri 2/6

5:42 pm-7:06 pm

1 stop24h 24m

Hartford Bradley Intl

Mon 2/9

1:56 pm-11:33 pm

2 stops10h 37m

$240

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Sun 2/1

9:09 am-7:36 pm

1 stop9h 27m

Hartford Bradley Intl

Sat 2/7

8:01 pm-8:04 am

1 stop13h 03m

$245

SpringfieldBoston

SGF - BOS

SGFBOS

Springfield-Branson

Tue 2/10

1:28 pm-11:46 pm

1 stop9h 18m

Boston Logan Intl

Wed 2/11

9:30 am-2:38 pm

1 stop6h 08m

$251

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Massachusetts

Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Massachusetts

What is the cheapest month to book a flight from Missouri to Massachusetts?

Currently, January is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $121). Flying from Missouri to Massachusetts in July is currently the most expensive (average of $281). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MA?

It’s typically best to fly out from Missouri to Massachusetts in the evening. Doing so could potentially save you 36% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Massachusetts?

Travelers seeking maximum savings on their Missouri to Massachusetts flight should consider departing on Monday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Massachusetts

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Missouri to Massachusetts to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,005 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,091 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,054 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,190 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Missouri to Massachusetts flight route?
This flight path from Missouri to Massachusetts was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Missouri to Massachusetts?
There are many flights that can get you from Missouri to Massachusetts in 5h 12m. Fly via Frontier, United Airlines, or American Airlines to get the fastest option. The distance from Missouri to Massachusetts is about 1234 mi. This flight may include one or multiple stops.
Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?
Yes. In addition to deals on Missouri to Massachusetts flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Massachusetts?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Massachusetts.
Can I find deals for business class flights from Missouri to Massachusetts?
Yes. Cheapflights offers flight deals from Missouri to Massachusetts by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Massachusetts?
Currently, January is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $121). Flying from Missouri to Massachusetts in July is currently the most expensive (average of $281). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to Massachusetts

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$100	Average$250	FlexibilityNo cancel fee	On-time62%
Spirit Airlines	Cheapest$124	Average$275	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$158	Average$469	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$216	Average$413	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$217	Average$458	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$302	Average$433	FlexibilityNo cancel fee	On-time63%

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$63+ Cheap flights from Missouri to Massachusetts

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Massachusetts

Cheapest flights from Missouri to MassachusettsExplore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Missouri to Massachusetts

Keep the following information in mind while searching for Missouri to Massachusetts flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Massachusetts that are best for you.

Best time to book a flight from Missouri to Massachusetts

Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Massachusetts

What is the cheapest month to book a flight from Missouri to Massachusetts?

What is the cheapest time of day to fly from MO to MA?

Find hourly flight availability from Missouri to Massachusetts. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

What is the cheapest day to fly from Missouri to Massachusetts?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Massachusetts. Price data was last updated on December 16, 2024.

Reviews of airlines servicing Massachusetts

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Missouri to Massachusetts to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Massachusetts. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Missouri to Massachusetts flight route?

How long is the flight from Missouri to Massachusetts?

Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?

How can I find direct flights from Missouri to Massachusetts?

Can I find deals for business class flights from Missouri to Massachusetts?

What is the cheapest month to book a flight from Missouri to Massachusetts?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Massachusetts

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Missouri to Massachusetts

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Cheapest flights from Missouri to Massachusetts
Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.