Massachusetts

$106+ Cheap flights from Missouri to Massachusetts

STL — BOS
Dec 4 — Dec 111
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Cheap flight deals from Missouri to Massachusetts

Cheapest flights from Missouri to Massachusetts

Thu 12/39:55 am -
Nonstop2h 54m
Mon 12/73:55 pm -
Nonstop3h 45m
Deal found 10/31$279
Thu 12/1710:35 am -
1 stop4h 19m
Fri 12/185:35 pm -
Nonstop3h 49m
Deal found 11/4$289
Wed 12/96:00 am -
2 stops7h 30m
Fri 12/112:30 pm -
Nonstop3h 35m
Deal found 10/31$294
Fri 12/410:30 am -
1 stop22h 43m
Sun 12/611:08 am -
1 stop23h 27m
Deal found 11/3$298
Fri 12/1110:30 am -
1 stop22h 43m
Sun 12/1311:08 am -
1 stop23h 27m
Deal found 11/4$301
Wed 12/98:15 am -
2 stops7h 05m
Sat 12/125:25 am -
1 stop5h 40m
Deal found 11/2$304
Thu 12/106:00 am -
2 stops7h 30m
Tue 12/157:10 am -
2 stops7h 35m
Deal found 11/2$309
Wed 12/168:32 pm -
2 stops11h 58m
Thu 1/710:29 am -
1 stop24h 47m
Deal found 10/30$314
Wed 11/255:00 am -
Nonstop2h 30m
Thu 11/2610:05 am -
Nonstop3h 05m
Deal found 11/3$317
Wed 11/256:35 pm -
2 stops12h 55m
Thu 12/311:57 am -
1 stop24h 20m
Deal found 11/1$318
Thu 11/266:09 pm -
1 stop15h 02m
Mon 11/3011:06 am -
1 stop13h 53m
Deal found 10/30$319
Sat 12/127:54 pm -
2 stops13h 19m
Mon 12/1411:08 am -
1 stop14h 04m
Deal found 10/31$320

Find flight deals from Missouri to Massachusetts

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(Delta)

One-way from

$106
(Frontier)

Popular in

February

Cheapest in

December

Average price

$466

Good round-trip deal

$333 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for Lambert-St Louis-Boston Logan Intl flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Boston Logan Intl flights.
From Missouri to Massachusetts
One-way flight from Missouri to Massachusetts
Highest demand for flights based on searches. 9% potential increase in price ($52 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Average for round-trip flights in November 2026
Price to beat on a round-trip flight from Missouri to Massachusetts.
Price to beat on a one-way flight from Missouri to Massachusetts.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Missouri to Massachusetts that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityBoston

MCI Kansas City - BOS Boston Logan Intl

MCIBOS

Kansas City

Tue 12/22

5:02 pm-1:18 am

1 stop7h 16m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$150

Kansas CityBoston

MCI Kansas City - BOS Boston Logan Intl

MCIBOS

Kansas City

Tue 2/16

12:30 pm-7:00 pm

1 stop5h 30m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$150

Kansas CityBoston

MCI Kansas City - BOS Boston Logan Intl

MCIBOS

Kansas City

Mon 2/15

3:24 pm-9:54 pm

1 stop5h 30m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$150
Quickest round-trip

St. LouisBoston

STL Lambert-St Louis - BOS Boston Logan Intl

STLBOS

Lambert-St Louis

Tue 11/24

5:00 am-8:30 am

Nonstop2h 30m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$159

St. LouisBoston

STL Lambert-St Louis - BOS Boston Logan Intl

STLBOS

Lambert-St Louis

Thu 12/10

1:20 pm-4:50 pm

Nonstop2h 30m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$159

St. LouisBoston

STL Lambert-St Louis - BOS Boston Logan Intl

STLBOS

Lambert-St Louis

Tue 12/29

5:00 am-8:30 am

Nonstop2h 30m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$159

St. LouisBoston

STL Lambert-St Louis - BOS Boston Logan Intl

STLBOS

Lambert-St Louis

Mon 11/23

10:15 am-1:45 pm

Nonstop2h 30m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$159

St. LouisBoston

STL Lambert-St Louis - BOS Boston Logan Intl

STLBOS

Lambert-St Louis

Mon 1/18

8:45 pm-12:15 am

Nonstop2h 30m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$159

St. LouisBoston

STL Lambert-St Louis - BOS Boston Logan Intl

STLBOS

Lambert-St Louis

Thu 12/31

6:04 am-12:10 pm

1 stop5h 06m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$164

ColumbiaBoston

COU Columbia Regional - BOS Boston Logan Intl

COUBOS

Columbia Regional

Thu 11/26

10:36 am-4:51 pm

1 stop5h 15m

Boston Logan Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$169

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Massachusetts

Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Missouri with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Missouri to Massachusetts

What is the cheapest month to book a flight from Missouri to Massachusetts?

Currently, November is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $459). Flying from Missouri to Massachusetts in February is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MA?

It’s typically best to fly out from Missouri to Massachusetts in the evening. Doing so could potentially save you 35% on the flight price compared to flying at noon, which is usually more expensive.

Weekly flight availability from Missouri to Massachusetts

The most flights from USMO to USMA are scheduled on a Monday (8 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Missouri to Massachusetts?

Airfare is below average for this route at the moment.
Missouri to Massachusetts flights typically cost between $391 and $637 in November.
The cheapest round-trip price found within the last 5 days was $317 on Southwest (Nov 25-Nov 26).

How far ahead should I book a flight from Missouri to Massachusetts?

Booking 84 days in advance of your planned departure date is, on average, the best time to get cheap flights from Missouri to Massachusetts. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest day to fly from Missouri to Massachusetts?

Travelers seeking maximum savings on their Missouri to Massachusetts flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Massachusetts

Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Missouri to Massachusetts to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

  • How popular is this Missouri to Massachusetts flight route?

  • How long is the flight from Missouri to Massachusetts?

    There are many flights that can get you from Missouri to Massachusetts in 3h 02m. Fly via Delta, Southwest, or American Airlines to get the fastest option. The distance from Missouri to Massachusetts is about 1252 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Massachusetts one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $80. Users have also found prices from $138 and $158 on American Airlines and Southwest, respectively.

  • Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?

    Yes. In addition to deals on Missouri to Massachusetts flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Massachusetts?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Massachusetts.

  • Can I find deals for business class flights from Missouri to Massachusetts?

    Yes. Cheapflights offers flight deals from Missouri to Massachusetts by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Massachusetts?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $459). Flying from Missouri to Massachusetts in February is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Missouri to Massachusetts

Top 6 airlines flying from Missouri to Massachusetts

AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$95Average$262FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$264Average$510FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$276Average$457FlexibilityNo cancel feeOn-time71%
DeltaCheapest$288Average$477FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$316Average$438FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$331Average$500FlexibilityNo cancel feeOn-time63%

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