How popular is this Missouri to Massachusetts flight route?

This flight path from Missouri to Massachusetts was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Missouri to Massachusetts?

There are many flights that can get you from Missouri to Massachusetts in 5h 15m. Fly via Frontier, American Airlines, or United Airlines to get the fastest option. The distance from Missouri to Massachusetts is about 1145 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Massachusetts ranges from 3.1 - 4.0 inches per month. March is typically the wettest month, when rainfall can reach 4.0 in. July is typically the driest time to visit Massachusetts when rainfall is around 3.1 in.

If weather is an important factor for your trip to Massachusetts, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?

Yes. In addition to deals on Missouri to Massachusetts flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Massachusetts?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Massachusetts.

Can I find deals for business class flights from Missouri to Massachusetts?

Yes. Cheapflights offers flight deals from Missouri to Massachusetts by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$62+ Flights from Missouri to Massachusetts

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Missouri to Massachusetts with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Massachusetts

Cheapest flights from Missouri to Massachusetts
Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Wed 12/311:33 pmSGF - BOS

1 stop9h 02mUnited Airlines

Wed 1/74:16 pmBOS - SGF

1 stop6h 42mUnited Airlines

Deal found 12/30

$439

Wed 12/317:05 amSTL - BOS

1 stop8h 38mAmerican Airlines

Thu 1/110:55 amBOS - STL

1 stop9h 35mAmerican Airlines

Deal found 12/29

$445

Tue 12/305:03 pmSGF - BOS

1 stop7h 04mDelta

Fri 1/25:40 amBOS - SGF

1 stop6h 00mDelta

Deal found 12/27

$469

Wed 12/315:00 amSTL - BOS

1 stop10h 43mAmerican Airlines

Tue 1/66:43 amBOS - STL

1 stop9h 21mAmerican Airlines

Deal found 12/28

$520

Tue 12/306:20 pmSGF - BOS

1 stop26h 24mUnited Airlines

Fri 1/26:01 amBOS - SGF

2 stops11h 21mUnited Airlines

Deal found 12/28

$529

Wed 12/315:00 amSTL - BDL

1 stop10h 40mAmerican Airlines

Sat 1/107:01 amBDL - STL

1 stop9h 03mAmerican Airlines

Deal found 12/28

$555

Tue 12/306:15 pmMCI - BOS

1 stop15h 35mMultiple Airlines

Mon 1/58:08 amBOS - MCI

2 stops34h 02mMultiple Airlines

Deal found 12/28

$566

Mon 12/2911:13 amMCI - BOS

1 stop21h 29mMultiple Airlines

Sat 1/35:45 amBOS - MCI

1 stop12h 25mMultiple Airlines

Deal found 12/28

$569

Mon 12/2911:13 amMCI - BOS

1 stop21h 29mMultiple Airlines

Mon 1/58:08 amBOS - MCI

2 stops34h 02mMultiple Airlines

Deal found 12/28

$587

Wed 12/315:00 amSTL - BDL

1 stop10h 40mAmerican Airlines

Sun 1/46:05 amBDL - STL

1 stop14h 25mAmerican Airlines

Deal found 12/28

$590

Tue 12/306:15 pmMCI - BOS

1 stop15h 35mMultiple Airlines

Sun 1/411:03 amBOS - MCI

1 stop24h 05mMultiple Airlines

Deal found 12/28

$592

Mon 12/2911:13 amMCI - BOS

1 stop21h 29mMultiple Airlines

Fri 1/212:29 pmBOS - MCI

1 stop11h 30mMultiple Airlines

Deal found 12/28

$601

Best flights from Missouri to Massachusetts
Discover carefully curated flight deals from Missouri to Massachusetts that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

Wed 1/215:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Mon 1/265:27 pmBOS - STL

2 stops31h 06mMultiple Airlines

Deal found 12/29

$153

Fri 1/235:42 pmSTL - BDL

1 stop24h 24mFrontier

Thu 1/298:31 pmBDL - STL

1 stop28h 02mFrontier

Deal found 12/28

$201

Sat 1/245:00 pmSGF - BOS

1 stop5h 44mAmerican Airlines

Sat 1/319:51 amBOS - SGF

1 stop7h 23mAmerican Airlines

Deal found 12/30

$252

Sat 1/176:40 amSTL - BDL

1 stop4h 15mSouthwest

Tue 1/2012:10 pmBDL - STL

1 stop7h 50mSouthwest

Deal found 12/28

$269

Tue 4/218:00 amSGF - BDL

1 stop5h 15mUnited Airlines

Wed 5/65:04 pmBDL - SGF

1 stop5h 55mUnited Airlines

Deal found 12/29

$271

Thu 1/2911:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Sun 2/17:00 amBOS - MCI

1 stop10h 09mSpirit Airlines

Deal found 12/29

$288

Fri 1/235:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Mon 2/93:43 pmBOS - STL

1 stop8h 50mMultiple Airlines

Deal found 12/30

$154

Thu 1/155:00 pmSGF - BDL

1 stop5h 55mDelta

Mon 1/192:49 pmBDL - SGF

1 stop7h 57mDelta

Deal found 12/29

$314

Fri 1/305:42 pmSTL - BDL

1 stop24h 24mMultiple Airlines

Mon 2/21:56 pmBDL - STL

2 stops10h 37mMultiple Airlines

Deal found 12/29

$161

Tue 3/33:49 pmSTL - BOS

1 stop18h 59mMultiple Airlines

Tue 3/1012:35 pmBOS - STL

1 stop23h 02mMultiple Airlines

Deal found 12/29

$164

Mon 4/275:11 pmMCI - BOS

2 stops29h 48mAlaska Airlines

Sat 5/25:05 pmBOS - MCI

1 stop24h 12mAlaska Airlines

Deal found 12/28

$448

Fri 1/2311:18 amSTL - BDL

2 stops10h 58mMultiple Airlines

Sun 1/258:31 pmBDL - STL

1 stop28h 02mMultiple Airlines

Deal found 12/28

$184

Tue 1/2010:17 amSTL - ALB

1 stop6h 23mAmerican Airlines

Tue 1/2712:11 pmALB - STL

1 stop6h 12mAmerican Airlines

Deal found 12/28

$256

Sat 2/218:17 pmSTL - BDL

1 stop16h 15mFrontier

Tue 2/249:49 amBDL - STL

2 stops22h 02mFrontier

Deal found 12/29

$266

Tue 1/135:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Thu 1/157:00 amBOS - STL

1 stop16h 34mMultiple Airlines

Deal found 12/28

$185

Fri 2/273:15 pmSGF - BDL

1 stop4h 51mUnited Airlines

Mon 3/24:43 pmBDL - SGF

1 stop6h 16mUnited Airlines

Deal found 12/27

$279

Sat 1/178:13 amSTL - BDL

1 stop5h 44mAmerican Airlines

Tue 1/204:14 pmBDL - STL

1 stop7h 58mAmerican Airlines

Deal found 12/29

$269

Thu 3/127:52 amSTL - BDL

1 stop10h 21mFrontier

Sun 3/158:08 pmBDL - STL

1 stop11h 59mFrontier

Deal found 12/29

$270

Sat 1/178:45 amSTL - BOS

Nonstop2h 35mSouthwest

Sun 1/186:25 amBOS - STL

Nonstop3h 20mSouthwest

Deal found 12/29

$297

Tue 1/276:30 amSTL - ALB

2 stops6h 35mUnited Airlines

Tue 2/34:20 pmALB - STL

1 stop7h 38mUnited Airlines

Deal found 12/28

$282

Fri 4/1011:26 amMCI - BOS

1 stop11h 41mSpirit Airlines

Mon 4/134:08 pmBOS - MCI

1 stop8h 51mSpirit Airlines

Deal found 12/29

$329

Thu 4/96:55 pmSGF - BOS

1 stop5h 18mDelta

Tue 4/143:55 pmBOS - SGF

1 stop6h 12mDelta

Deal found 12/29

$334

Wed 1/289:33 amSTL - ALB

1 stop4h 47mAmerican Airlines

Sat 1/3112:11 pmALB - STL

1 stop5h 50mAmerican Airlines

Deal found 12/29

$277

Thu 1/85:11 pmSTL - BDL

1 stop25h 28mFrontier

Thu 1/228:31 pmBDL - STL

1 stop14h 52mFrontier

Deal found 12/29

$288

Fri 1/165:04 pmMCI - BDL

1 stop25h 16mMultiple Airlines

Mon 1/195:56 pmBDL - MCI

1 stop23h 13mMultiple Airlines

Deal found 12/29

$218

Tue 1/138:09 amCOU - BOS

1 stop8h 10mUnited Airlines

Sat 1/176:00 amBOS - COU

1 stop5h 42mUnited Airlines

Deal found 12/29

$298

Tue 1/278:20 amSTL - ALB

1 stop6h 55mSouthwest

Thu 1/293:40 pmALB - STL

2 stops6h 20mSouthwest

Deal found 12/29

$333

Thu 1/156:25 amSTL - ALB

1 stop6h 37mDelta

Sun 1/186:00 amALB - STL

1 stop6h 05mDelta

Deal found 12/28

$351

Tue 1/278:30 amSTL - ALB

1 stop4h 35mUnited Airlines

Thu 1/296:00 amALB - STL

1 stop7h 29mUnited Airlines

Deal found 12/29

$302

Tue 1/276:15 amMCI - ALB

1 stop5h 05mSouthwest

Tue 1/273:40 pmALB - MCI

2 stops7h 40mSouthwest

Deal found 12/28

$342

Last-minute flights from Missouri to Massachusetts
Discover last-minute flight deals from Missouri to Massachusetts. Data last updated December 30, 2025 and is based on user searches.

Mon 1/125:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Sat 1/1712:10 pmBOS - STL

1 stop11h 24mMultiple Airlines

Deal found 12/28

$156

Tue 1/135:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Sat 1/1712:10 pmBOS - STL

1 stop11h 24mMultiple Airlines

Deal found 12/28

$142

Wed 1/145:11 pmSTL - BOS

1 stop16h 59mFrontier

Sat 1/1712:10 pmBOS - STL

1 stop11h 24mFrontier

Deal found 12/28

$133

Wed 1/215:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Wed 2/117:00 amBOS - STL

1 stop16h 27mMultiple Airlines

Deal found 12/30

$143

Wed 1/215:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Mon 1/263:43 pmBOS - STL

1 stop8h 50mMultiple Airlines

Deal found 12/29

$151

Sat 1/248:22 pmSTL - BOS

1 stop27h 51mMultiple Airlines

Mon 2/93:43 pmBOS - STL

1 stop8h 50mMultiple Airlines

Deal found 12/30

$164

Mon 1/2611:26 amMCI - BOS

1 stop11h 31mMultiple Airlines

Mon 2/26:00 amBOS - MCI

1 stop6h 50mMultiple Airlines

Deal found 12/28

$166

Tue 1/275:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Sun 2/13:43 pmBOS - STL

1 stop18h 38mMultiple Airlines

Deal found 12/28

$165

Fri 1/3011:18 amSTL - BOS

1 stop11h 01mMultiple Airlines

Wed 2/43:43 pmBOS - STL

1 stop8h 50mMultiple Airlines

Deal found 12/28

$132

Fri 1/3011:18 amSTL - BOS

1 stop11h 01mMultiple Airlines

Sun 2/16:00 amBOS - STL

1 stop25h 51mMultiple Airlines

Deal found 12/30

$157

Fri 1/305:42 pmSTL - BDL

1 stop24h 24mMultiple Airlines

Mon 2/21:56 pmBDL - STL

2 stops10h 37mMultiple Airlines

Deal found 12/29

$161

Sat 1/3112:12 pmSTL - BOS

1 stop10h 07mMultiple Airlines

Wed 2/47:00 amBOS - STL

1 stop17h 33mMultiple Airlines

Deal found 12/28

$154

One-way flights from Missouri to Massachusetts
Search for one-way flight options from Missouri to Massachusetts. Find affordable one-way fares based on user searches. Data last updated December 30, 2025.

Sat 2/143:49 pmSTL - BOS

1 stop16h 17mFrontier

Deal found 12/29

$62

Sat 2/711:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/29

$68

Wed 2/253:49 pmSTL - BOS

1 stop16h 17mFrontier

Deal found 12/30

$68

Fri 2/65:42 pmSTL - BDL

1 stop24h 24mFrontier

Deal found 12/28

$68

Tue 1/275:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Deal found 12/29

$69

Thu 1/2211:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/29

$74

Mon 1/2611:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/27

$75

Mon 1/265:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Deal found 12/29

$80

Thu 2/511:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/29

$84

Sat 5/212:12 pmMCI - BOS

1 stop10h 47mSpirit Airlines

Deal found 12/29

$85

Sat 1/3112:12 pmSTL - BOS

1 stop10h 07mMultiple Airlines

Deal found 12/29

$91

Fri 1/2311:26 amMCI - BOS

1 stop28h 02mSpirit Airlines

Deal found 12/29

$93

Find flight deals from Missouri to Massachusetts

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$132 (Kiwi.com)
One-way from	$62 (Trip.com)
Popular in	November
Cheapest in	September
Average price	$435
Good round-trip deal	$468 or less
Good one-way deal	$303 or less

Provider with most accurate pricing for Lambert-St Louis-Boston Logan Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Boston Logan Intl flights.

Search Deals

From Missouri to Massachusetts

Search Deals

One-way flight from Missouri to Massachusetts

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Missouri to Massachusetts.

Search Deals

Price to beat on a one-way flight from Missouri to Massachusetts.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Massachusetts that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Wed 1/21

5:42 pm-2:38 pm

1 stop19h 56m

Boston Logan Intl

Mon 1/26

5:27 pm-11:33 pm

2 stops31h 06m

$153

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Fri 1/23

5:42 pm-2:38 pm

1 stop19h 56m

Boston Logan Intl

Mon 2/9

3:43 pm-11:33 pm

1 stop8h 50m

$154

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Fri 1/30

5:42 pm-7:06 pm

1 stop24h 24m

Hartford Bradley Intl

Mon 2/2

1:56 pm-11:33 pm

2 stops10h 37m

$161

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Tue 3/3

3:49 pm-11:48 am

1 stop18h 59m

Boston Logan Intl

Tue 3/10

12:35 pm-10:37 am

1 stop23h 02m

$164

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Fri 1/23

11:18 am-11:16 pm

2 stops10h 58m

Hartford Bradley Intl

Sun 1/25

8:31 pm-11:33 pm

1 stop28h 02m

$184

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Tue 1/13

5:11 pm-2:38 pm

1 stop20h 27m

Boston Logan Intl

Thu 1/15

7:00 am-10:34 pm

1 stop16h 34m

$185

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Fri 1/23

5:42 pm-7:06 pm

1 stop24h 24m

Hartford Bradley Intl

Thu 1/29

8:31 pm-11:33 pm

1 stop28h 02m

$201

Kansas CityHartford

MCI - BDL

MCIBDL

Kansas City

Fri 1/16

5:04 pm-7:20 pm

1 stop25h 16m

Hartford Bradley Intl

Mon 1/19

5:56 pm-4:09 pm

1 stop23h 13m

$218

SpringfieldBoston

SGF - BOS

SGFBOS

Springfield-Branson

Sat 1/24

5:00 pm-11:44 pm

1 stop5h 44m

Boston Logan Intl

Sat 1/31

9:51 am-4:14 pm

1 stop7h 23m

$252

St. LouisAlbany

STL - ALB

STLALB

Lambert-St Louis

Tue 1/20

10:17 am-5:40 pm

1 stop6h 23m

Albany Intl

Tue 1/27

12:11 pm-5:23 pm

1 stop6h 12m

$256

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Massachusetts

Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Massachusetts

What is the cheapest month to book a flight from Missouri to Massachusetts?

Currently, January is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $122). Flying from Missouri to Massachusetts in July is currently the most expensive (average of $281). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MA?

It’s typically best to fly out from Missouri to Massachusetts in the evening. Doing so could potentially save you 52% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Massachusetts?

Travelers seeking maximum savings on their Missouri to Massachusetts flight should consider departing on Wednesday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Massachusetts

The most flights from USMO to USMA are scheduled on a Monday (11 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (3 on average).

Reviews of airlines servicing Massachusetts

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Missouri to Massachusetts to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,251 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,014 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,121 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,074 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,235 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Missouri to Massachusetts flight route?
This flight path from Missouri to Massachusetts was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Missouri to Massachusetts?
There are many flights that can get you from Missouri to Massachusetts in 5h 15m. Fly via Frontier, American Airlines, or United Airlines to get the fastest option. The distance from Missouri to Massachusetts is about 1145 mi. This flight may include one or multiple stops.
Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?
Yes. In addition to deals on Missouri to Massachusetts flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Massachusetts?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Massachusetts.
Can I find deals for business class flights from Missouri to Massachusetts?
Yes. Cheapflights offers flight deals from Missouri to Massachusetts by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Massachusetts?
Currently, January is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $122). Flying from Missouri to Massachusetts in July is currently the most expensive (average of $281). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to Massachusetts

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$100	Average$250	FlexibilityNo cancel fee	On-time62%
Spirit Airlines	Cheapest$124	Average$276	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$153	Average$488	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$216	Average$410	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$217	Average$456	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$300	Average$436	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$62+ Cheap flights from Missouri to Massachusetts

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Massachusetts with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to Massachusetts

Cheapest flights from Missouri to MassachusettsExplore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Find flight deals from Missouri to Massachusetts

Keep the following information in mind while searching for Missouri to Massachusetts flight deals. Data was last updated December 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Massachusetts that are best for you.

Best time to book a flight from Missouri to Massachusetts

Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Massachusetts

What is the cheapest month to book a flight from Missouri to Massachusetts?

What is the cheapest time of day to fly from MO to MA?

Find hourly flight availability from Missouri to Massachusetts. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 30, 2025.

What is the cheapest day to fly from Missouri to Massachusetts?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Massachusetts. Price data was last updated on December 27, 2025.

Weekly flight availability from Missouri to Massachusetts

Reviews of airlines servicing Massachusetts

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Missouri to Massachusetts to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Massachusetts. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Missouri to Massachusetts flight route?

How long is the flight from Missouri to Massachusetts?

Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?

How can I find direct flights from Missouri to Massachusetts?

Can I find deals for business class flights from Missouri to Massachusetts?

What is the cheapest month to book a flight from Missouri to Massachusetts?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Massachusetts

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Missouri to Massachusetts

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Missouri to Massachusetts
Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.