How popular is this Missouri to Massachusetts flight route?

This flight path from Missouri to Massachusetts was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Missouri to Massachusetts?

There are many flights that can get you from Missouri to Massachusetts in 7h 27m. Fly via United Airlines, American Airlines, or Spirit Airlines to get the fastest option. The distance from Missouri to Massachusetts is about 1234 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Massachusetts ranges from 3.1 - 4.0 inches per month. March is typically the wettest month, when rainfall can reach 4.0 in. July is typically the driest time to visit Massachusetts when rainfall is around 3.1 in.

If weather is an important factor for your trip to Massachusetts, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?

Yes. In addition to deals on Missouri to Massachusetts flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Massachusetts?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Massachusetts.

Can I find deals for business class flights from Missouri to Massachusetts?

Yes. Cheapflights offers flight deals from Missouri to Massachusetts by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$65+ Flights from Missouri to Massachusetts

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheap flight deals from Missouri to Massachusetts

Cheapest flights from Missouri to Massachusetts
Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Wed 12/173:30 pmSTL - BOS

1 stop17h 22mFrontier

Thu 1/86:00 amBOS - STL

1 stop9h 48mFrontier

Deal found 12/7

$174

Wed 12/173:30 pmSTL - BOS

1 stop17h 22mMultiple Airlines

Thu 1/85:23 pmBOS - STL

2 stops22h 25mMultiple Airlines

Deal found 12/7

$228

Thu 12/184:27 pmSTL - BOS

1 stop16h 34mMultiple Airlines

Thu 1/86:00 amBOS - STL

1 stop9h 48mMultiple Airlines

Deal found 12/7

$229

Thu 12/113:30 pmSTL - BDL

1 stop19h 54mFrontier

Sun 12/142:03 pmBDL - STL

1 stop19h 56mFrontier

Deal found 12/7

$248

Wed 12/2412:07 pmSGF - BOS

1 stop8h 13mAmerican Airlines

Wed 12/315:40 pmBOS - SGF

1 stop5h 48mAmerican Airlines

Deal found 12/6

$269

Sat 12/133:30 pmSTL - BOS

1 stop16h 57mFrontier

Sun 12/1412:57 pmBOS - STL

1 stop21h 02mFrontier

Deal found 12/7

$271

Wed 12/243:14 pmSGF - BOS

2 stops7h 40mUnited Airlines

Wed 12/317:45 amBOS - SGF

1 stop7h 53mUnited Airlines

Deal found 12/6

$274

Wed 12/243:14 pmSGF - BOS

2 stops7h 40mUnited Airlines

Thu 1/15:20 amBOS - SGF

2 stops10h 18mUnited Airlines

Deal found 12/6

$279

Thu 12/256:00 amMCI - ALB

1 stop7h 07mAmerican Airlines

Thu 1/15:00 amALB - MCI

1 stop7h 26mAmerican Airlines

Deal found 12/7

$281

Sat 12/206:15 pmMCI - BOS

1 stop15h 35mSpirit Airlines

Sat 1/107:00 amBOS - MCI

1 stop10h 09mSpirit Airlines

Deal found 12/7

$281

Wed 12/173:30 pmSTL - BOS

1 stop17h 22mMultiple Airlines

Sat 1/312:29 pmBOS - STL

2 stops22h 11mMultiple Airlines

Deal found 12/7

$285

Wed 12/244:27 pmSTL - BOS

1 stop16h 25mFrontier

Thu 1/112:22 pmBOS - STL

1 stop11h 11mFrontier

Deal found 12/6

$297

Best flights from Missouri to Massachusetts
Discover carefully curated flight deals from Missouri to Massachusetts that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 8, 2025.

Tue 1/65:11 pmSTL - BOS

1 stop15h 50mMultiple Airlines

Fri 1/96:00 amBOS - STL

1 stop9h 48mMultiple Airlines

Deal found 12/7

$196

Fri 1/161:28 pmSGF - BOS

1 stop7h 27mUnited Airlines

Tue 1/204:49 pmBOS - SGF

1 stop6h 09mUnited Airlines

Deal found 12/7

$260

Wed 12/2412:07 pmSGF - BOS

1 stop8h 13mAmerican Airlines

Wed 12/314:36 pmBOS - SGF

1 stop6h 52mAmerican Airlines

Deal found 12/5

$269

Thu 3/511:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Wed 3/117:00 amBOS - MCI

1 stop9h 29mSpirit Airlines

Deal found 12/7

$282

Sun 3/810:42 amSTL - BOS

1 stop13h 22mFrontier

Mon 3/911:06 amBOS - STL

2 stops12h 27mFrontier

Deal found 12/5

$294

Sat 1/178:45 amSTL - BOS

Nonstop2h 35mSouthwest

Sun 1/186:25 amBOS - STL

Nonstop3h 20mSouthwest

Deal found 12/6

$297

Tue 2/176:35 amSTL - ALB

1 stop4h 17mDelta

Thu 2/195:35 amALB - STL

1 stop7h 48mDelta

Deal found 12/6

$302

Sat 1/3112:12 pmSTL - BDL

1 stop9h 47mMultiple Airlines

Mon 2/27:13 pmBDL - STL

2 stops29h 20mMultiple Airlines

Deal found 12/5

$198

Thu 1/295:42 pmSTL - BDL

2 stops18h 50mMultiple Airlines

Sun 2/18:31 pmBDL - STL

1 stop28h 02mMultiple Airlines

Deal found 12/5

$226

Wed 12/2412:07 pmSGF - BOS

1 stop8h 13mAmerican Airlines

Thu 1/15:53 amBOS - SGF

1 stop6h 06mAmerican Airlines

Deal found 12/6

$269

Wed 12/243:14 pmSGF - BOS

2 stops7h 40mUnited Airlines

Wed 12/317:45 amBOS - SGF

1 stop7h 53mUnited Airlines

Deal found 12/5

$274

Wed 1/145:04 pmMCI - BOS

1 stop20h 34mMultiple Airlines

Sun 1/188:47 amBOS - MCI

2 stops11h 55mMultiple Airlines

Deal found 12/6

$248

Wed 12/243:14 pmSGF - BOS

2 stops7h 40mUnited Airlines

Thu 1/15:20 amBOS - SGF

2 stops10h 18mUnited Airlines

Deal found 12/6

$279

Thu 12/256:00 amMCI - ALB

1 stop7h 07mAmerican Airlines

Thu 1/15:00 amALB - MCI

1 stop7h 26mAmerican Airlines

Deal found 12/7

$281

Tue 2/172:55 pmSTL - ALB

2 stops6h 45mSouthwest

Thu 2/198:35 amALB - STL

2 stops8h 20mSouthwest

Deal found 12/6

$312

Fri 3/65:24 pmSTL - BOS

1 stop15h 47mFrontier

Mon 3/910:52 amBOS - STL

1 stop23h 55mFrontier

Deal found 12/5

$314

Sat 1/177:10 amSTL - BOS

1 stop6h 10mDelta

Sun 1/185:29 amBOS - STL

1 stop5h 10mDelta

Deal found 12/7

$317

Sat 1/318:05 amSTL - BDL

1 stop5h 17mUnited Airlines

Mon 2/24:46 pmBDL - STL

1 stop7h 12mUnited Airlines

Deal found 12/5

$286

Sat 1/316:00 amSTL - BDL

1 stop5h 34mAmerican Airlines

Mon 2/24:50 pmBDL - STL

1 stop5h 25mAmerican Airlines

Deal found 12/6

$286

Wed 12/315:42 pmMCI - BDL

1 stop4h 32mDelta

Thu 1/86:00 amBDL - MCI

1 stop7h 44mDelta

Deal found 12/6

$320

Thu 1/292:35 pmSTL - BDL

1 stop6h 15mSouthwest

Wed 2/115:30 amBDL - STL

1 stop6h 45mSouthwest

Deal found 12/7

$329

Thu 12/184:27 pmSTL - BOS

1 stop16h 34mMultiple Airlines

Thu 1/85:23 pmBOS - STL

2 stops22h 25mMultiple Airlines

Deal found 12/7

$279

Thu 1/15:55 pmSTL - ALB

1 stop4h 28mDelta

Sat 1/35:40 amALB - STL

1 stop4h 35mDelta

Deal found 12/7

$321

Tue 12/236:20 pmSGF - BOS

1 stop5h 25mUnited Airlines

Wed 12/317:45 amBOS - SGF

1 stop7h 53mUnited Airlines

Deal found 12/5

$304

Sun 1/119:10 amSTL - ALB

1 stop6h 05mSouthwest

Wed 1/141:00 pmALB - STL

2 stops7h 00mSouthwest

Deal found 12/7

$337

Thu 1/15:12 amMCI - BDL

1 stop5h 54mAmerican Airlines

Tue 1/64:50 pmBDL - MCI

1 stop6h 49mAmerican Airlines

Deal found 12/7

$309

Sun 1/410:57 amSTL - BOS

2 stops19h 26mMultiple Airlines

Sun 1/117:00 amBOS - STL

1 stop26h 05mMultiple Airlines

Deal found 12/7

$287

Thu 1/15:55 pmSTL - ALB

1 stop4h 28mDelta

Fri 1/25:40 amALB - STL

1 stop4h 44mDelta

Deal found 12/7

$321

Thu 1/17:40 amMCI - BDL

1 stop5h 36mUnited Airlines

Tue 1/610:07 amBDL - MCI

1 stop6h 03mUnited Airlines

Deal found 12/6

$309

Thu 2/194:35 pmMCI - BDL

1 stop5h 10mSouthwest

Tue 2/246:00 amBDL - MCI

1 stop5h 35mSouthwest

Deal found 12/6

$348

Last-minute flights from Missouri to Massachusetts
Discover last-minute flight deals from Missouri to Massachusetts. Data last updated December 8, 2025 and is based on user searches.

Wed 12/173:30 pmSTL - BOS

1 stop17h 22mFrontier

Thu 1/86:00 amBOS - STL

1 stop9h 48mFrontier

Deal found 12/7

$174

Tue 1/65:11 pmSTL - BOS

1 stop15h 50mMultiple Airlines

Fri 1/96:00 amBOS - STL

1 stop9h 48mMultiple Airlines

Deal found 12/7

$196

Wed 1/75:11 pmSTL - BOS

1 stop16h 00mMultiple Airlines

Wed 1/143:43 pmBOS - STL

1 stop7h 51mMultiple Airlines

Deal found 12/7

$179

Mon 1/1211:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Sat 1/177:00 amBOS - MCI

1 stop10h 09mSpirit Airlines

Deal found 12/6

$180

Mon 1/128:26 pmMCI - BOS

2 stops27h 47mMultiple Airlines

Sat 1/177:00 amBOS - MCI

1 stop10h 09mMultiple Airlines

Deal found 12/6

$185

Mon 1/128:26 pmMCI - BOS

2 stops27h 47mMultiple Airlines

Mon 1/1912:10 pmBOS - MCI

1 stop28h 59mMultiple Airlines

Deal found 12/6

$187

Mon 1/128:26 pmMCI - BOS

2 stops27h 47mMultiple Airlines

Thu 1/225:27 pmBOS - MCI

1 stop18h 04mMultiple Airlines

Deal found 12/6

$192

Mon 1/1211:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Wed 1/215:34 amBOS - MCI

1 stop29h 57mSpirit Airlines

Deal found 12/6

$197

Thu 1/1511:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Sat 1/177:00 amBOS - MCI

1 stop10h 09mSpirit Airlines

Deal found 12/6

$199

Wed 1/215:42 pmSTL - BOS

1 stop28h 37mMultiple Airlines

Wed 1/283:43 pmBOS - STL

1 stop8h 50mMultiple Airlines

Deal found 12/7

$142

Fri 1/2312:45 pmMCI - BOS

1 stop11h 28mFrontier

Mon 1/266:00 amBOS - MCI

1 stop6h 50mFrontier

Deal found 12/7

$128

Sat 1/3112:12 pmSTL - BDL

1 stop9h 47mMultiple Airlines

Mon 2/27:13 pmBDL - STL

2 stops29h 20mMultiple Airlines

Deal found 12/5

$198

One-way flights from Missouri to Massachusetts
Search for one-way flight options from Missouri to Massachusetts. Find affordable one-way fares based on user searches. Data last updated December 8, 2025.

Mon 2/98:22 pmSTL - BOS

1 stop26h 43mFrontier

Deal found 12/7

$65

Sun 1/115:11 pmSTL - BDL

1 stop25h 13mFrontier

Deal found 12/8

$68

Fri 1/2312:45 pmMCI - BOS

1 stop11h 28mFrontier

Deal found 12/6

$70

Wed 12/173:30 pmSTL - BOS

1 stop17h 22mFrontier

Deal found 12/8

$73

Tue 2/35:42 pmSTL - BOS

1 stop19h 56mMultiple Airlines

Deal found 12/7

$75

Wed 1/218:22 pmSTL - BOS

1 stop27h 51mFrontier

Deal found 12/7

$80

Fri 2/68:22 pmSTL - BOS

1 stop27h 51mFrontier

Deal found 12/6

$82

Mon 1/1211:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/7

$85

Wed 2/48:22 pmSTL - BOS

1 stop27h 51mFrontier

Deal found 12/6

$86

Sun 2/811:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/7

$91

Tue 12/163:30 pmSTL - BOS

1 stop17h 31mMultiple Airlines

Deal found 12/8

$91

Sat 2/78:22 pmSTL - BOS

1 stop27h 52mFrontier

Deal found 12/7

$93

Find flight deals from Missouri to Massachusetts

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$128 (Frontier)
One-way from	$65 (Kiwi.com)
Popular in	November
Cheapest in	September
Average price	$423
Good round-trip deal	$496 or less
Good one-way deal	$277 or less

Provider with most accurate pricing for Lambert-St Louis-Boston Logan Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Boston Logan Intl flights.

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From Missouri to Massachusetts

Search Deals

One-way flight from Missouri to Massachusetts

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Missouri to Massachusetts.

Search Deals

Price to beat on a one-way flight from Missouri to Massachusetts.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Massachusetts that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Tue 1/6

5:11 pm-10:01 am

1 stop15h 50m

Boston Logan Intl

Fri 1/9

6:00 am-2:48 pm

1 stop9h 48m

$196

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Sat 1/31

12:12 pm-10:59 pm

1 stop9h 47m

Hartford Bradley Intl

Mon 2/2

7:13 pm-11:33 pm

2 stops29h 20m

$198

St. LouisHartford

STL - BDL

STLBDL

Lambert-St Louis

Thu 1/29

5:42 pm-1:32 pm

2 stops18h 50m

Hartford Bradley Intl

Sun 2/1

8:31 pm-11:33 pm

1 stop28h 02m

$226

Kansas CityBoston

MCI - BOS

MCIBOS

Kansas City

Wed 1/14

5:04 pm-2:38 pm

1 stop20h 34m

Boston Logan Intl

Sun 1/18

8:47 am-7:42 pm

2 stops11h 55m

$248

SpringfieldBoston

SGF - BOS

SGFBOS

Springfield-Branson

Fri 1/16

1:28 pm-9:55 pm

1 stop7h 27m

Boston Logan Intl

Tue 1/20

4:49 pm-9:58 pm

1 stop6h 09m

$260

SpringfieldBoston

SGF - BOS

SGFBOS

Springfield-Branson

Wed 12/24

12:07 pm-9:20 pm

1 stop8h 13m

Boston Logan Intl

Wed 12/31

4:36 pm-10:28 pm

1 stop6h 52m

$269

SpringfieldBoston

SGF - BOS

SGFBOS

Springfield-Branson

Wed 12/24

12:07 pm-9:20 pm

1 stop8h 13m

Boston Logan Intl

Thu 1/1

5:53 am-10:59 am

1 stop6h 06m

$269

SpringfieldBoston

SGF - BOS

SGFBOS

Springfield-Branson

Wed 12/24

3:14 pm-11:54 pm

2 stops7h 40m

Boston Logan Intl

Wed 12/31

7:45 am-2:38 pm

1 stop7h 53m

$274

SpringfieldBoston

SGF - BOS

SGFBOS

Springfield-Branson

Wed 12/24

3:14 pm-11:54 pm

2 stops7h 40m

Boston Logan Intl

Thu 1/1

5:20 am-2:38 pm

2 stops10h 18m

$279

St. LouisBoston

STL - BOS

STLBOS

Lambert-St Louis

Thu 12/18

4:27 pm-10:01 am

1 stop16h 34m

Boston Logan Intl

Thu 1/8

5:23 pm-2:48 pm

2 stops22h 25m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Massachusetts

Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Massachusetts

What is the cheapest month to book a flight from Missouri to Massachusetts?

Currently, January is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $116). Flying from Missouri to Massachusetts in July is currently the most expensive (average of $281). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MA?

It’s typically best to fly out from Missouri to Massachusetts in the evening. Doing so could potentially save you 35% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Massachusetts?

Travelers seeking maximum savings on their Missouri to Massachusetts flight should consider departing on Monday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Massachusetts

The most flights from USMO to USMA are scheduled on a Friday (14 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (6 on average).

Reviews of airlines servicing Massachusetts

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Missouri to Massachusetts to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,254 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,254 reviews

Southwest

8.0

Very good

4,254 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,011 reviews

Southwest

8.0

Very good

4,254 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,089 reviews

Southwest

8.0

Very good

4,254 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,045 reviews

Southwest

8.0

Very good

4,254 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,168 reviews

Southwest

8.0

Very good

4,254 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Missouri to Massachusetts flight route?
This flight path from Missouri to Massachusetts was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Missouri to Massachusetts?
There are many flights that can get you from Missouri to Massachusetts in 7h 27m. Fly via United Airlines, American Airlines, or Spirit Airlines to get the fastest option. The distance from Missouri to Massachusetts is about 1234 mi. This flight may include one or multiple stops.
Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?
Yes. In addition to deals on Missouri to Massachusetts flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Massachusetts?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Massachusetts.
Can I find deals for business class flights from Missouri to Massachusetts?
Yes. Cheapflights offers flight deals from Missouri to Massachusetts by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Massachusetts?
Currently, January is the cheapest month in which you can book a flight from Missouri to Massachusetts (average of $116). Flying from Missouri to Massachusetts in July is currently the most expensive (average of $281). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to Massachusetts

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$75	Average$250	FlexibilityNo cancel fee	On-time62%
Spirit Airlines	Cheapest$124	Average$274	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$158	Average$474	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$216	Average$410	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$218	Average$482	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$304	Average$433	FlexibilityNo cancel fee	On-time63%

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$65+ Cheap flights from Missouri to Massachusetts

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Massachusetts

Cheapest flights from Missouri to MassachusettsExplore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Find flight deals from Missouri to Massachusetts

Keep the following information in mind while searching for Missouri to Massachusetts flight deals. Data was last updated December 8, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Massachusetts that are best for you.

Best time to book a flight from Missouri to Massachusetts

Have a flexible travel schedule? Discover the best time to fly to Massachusetts from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Massachusetts

What is the cheapest month to book a flight from Missouri to Massachusetts?

What is the cheapest time of day to fly from MO to MA?

Find hourly flight availability from Missouri to Massachusetts. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

What is the cheapest day to fly from Missouri to Massachusetts?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Massachusetts. Price data was last updated on December 16, 2024.

Weekly flight availability from Missouri to Massachusetts

Reviews of airlines servicing Massachusetts

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Missouri to Massachusetts to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Massachusetts. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Missouri to Massachusetts flight route?

How long is the flight from Missouri to Massachusetts?

Can I find deals for flights from Missouri to Massachusetts that include hotel bookings?

How can I find direct flights from Missouri to Massachusetts?

Can I find deals for business class flights from Missouri to Massachusetts?

What is the cheapest month to book a flight from Missouri to Massachusetts?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Massachusetts

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Missouri to Massachusetts

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Cheapest flights from Missouri to Massachusetts
Explore the most affordable flight options available from Missouri to Massachusetts. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.