$159+ Cheap flights from Knoxville to Manchester, NH (TYS - MHT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MHT
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Manchester with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Manchester
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Cheapest flights from Knoxville to ManchesterExplore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:05 pm -
1 stop5h 31m
Tue 10/206:00 am -
1 stop4h 25m
Deal found 9/22![American Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:05 pm -
1 stop5h 31m
Sun 11/16:01 am -
1 stop4h 32m
Deal found 9/23![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:05 pm -
1 stop5h 31m
Sun 10/186:00 am -
1 stop4h 25m
Deal found 9/19![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:20 am -
1 stop4h 49m
Tue 10/206:00 am -
1 stop4h 25m
Deal found 9/22![American Airlines logo]()
$412
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:35 pm -
1 stop4h 24m
Sat 10/319:25 am -
1 stop5h 23m
Deal found 9/21![United Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:20 am -
2 stops13h 35m
Sun 11/15:20 pm -
1 stop4h 20m
Deal found 9/23![Southwest logo]()
$423
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:42 am -
2 stops8h 19m
Tue 10/209:25 am -
1 stop5h 17m
Deal found 9/22![United Airlines logo]()
$453
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/213:24 pm -
1 stop7h 37m
Sun 1/31:14 pm -
1 stop4h 42m
Deal found 9/22![American Airlines logo]()
$468
Best flights from Knoxville to ManchesterDiscover carefully curated flight deals from Knoxville to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Knoxville to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:05 pm -
1 stop5h 31m
Sun 10/186:00 am -
1 stop4h 25m
Deal found 9/19![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:35 pm -
1 stop4h 24m
Sat 10/319:25 am -
1 stop5h 23m
Deal found 9/21![United Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:20 am -
2 stops13h 35m
Sun 11/15:20 pm -
1 stop4h 20m
Deal found 9/23![Southwest logo]()
$423
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
2 stops12h 45m
Mon 10/261:40 pm -
2 stops9h 05m
Deal found 9/21![Southwest logo]()
$493
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:25 pm -
1 stop4h 31m
Tue 10/209:25 am -
2 stops11h 24m
Deal found 9/22![United Airlines logo]()
$507
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/136:35 am -
1 stop7h 50m
Mon 2/1511:35 am -
2 stops11h 40m
Deal found 9/20![Southwest logo]()
$569
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:50 pm -
2 stops11h 05m
Sun 10/188:30 am -
2 stops10h 35m
Deal found 9/19![Southwest logo]()
$604
Last-minute flights from Knoxville to ManchesterDiscover last-minute flight deals from Knoxville to Manchester. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Manchester. Data last updated September 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:20 am -
1 stop4h 49m
Tue 10/206:00 am -
1 stop4h 25m
Deal found 9/22![American Airlines logo]()
$412
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:42 am -
2 stops8h 19m
Tue 10/209:25 am -
1 stop5h 17m
Deal found 9/22![United Airlines logo]()
$453
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:00 pm -
2 stops9h 45m
Tue 10/206:45 am -
2 stops9h 55m
Deal found 9/22![Southwest logo]()
$478
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:05 pm -
1 stop5h 31m
Tue 10/206:00 am -
1 stop4h 25m
Deal found 9/22![American Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:05 pm -
1 stop5h 31m
Sun 10/186:00 am -
1 stop4h 25m
Deal found 9/19![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:35 pm -
1 stop4h 24m
Sat 10/319:25 am -
1 stop5h 23m
Deal found 9/21![United Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:05 pm -
1 stop5h 31m
Sun 11/16:01 am -
1 stop4h 32m
Deal found 9/23![American Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:20 am -
2 stops13h 35m
Sun 11/15:20 pm -
1 stop4h 20m
Deal found 9/23![Southwest logo]()
$423
One-way flights from Knoxville to ManchesterSearch for one-way flight options from Knoxville to Manchester. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Knoxville to Manchester. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:05 pm -
1 stop6h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$159
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:30 pm -
2 stops7h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$164
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:35 pm -
1 stop4h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![United Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:05 pm -
1 stop5h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$224
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
1 stop4h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:35 pm -
1 stop4h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$241
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:35 pm -
1 stop5h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:00 pm -
2 stops9h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:42 am -
2 stops8h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$270
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:00 pm -
2 stops9h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:08 pm -
3 stops41h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$282
Find flight deals from Knoxville to Manchester
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (American Airlines) |
One-way from | $159 (American Airlines) |
Popular in | April |
Cheapest in | February |
Average price | $376 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Tue 10/20
7:17 am-11:45 am
1 stop4h 28m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$159
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Tue 11/10
4:30 pm-11:59 pm
2 stops7h 29m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$164
Quickest round-trip
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Tue 11/3
7:35 pm-11:59 pm
1 stop4h 24m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Mon 11/16
7:35 pm-11:59 pm
1 stop4h 24m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Tue 10/13
6:05 pm-11:36 pm
1 stop5h 31m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$224
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Fri 10/23
10:42 am-7:01 pm
2 stops8h 19m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$230
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Tue 10/6
1:35 pm-7:01 pm
1 stop5h 26m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$259
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Tue 10/20
10:42 am-7:01 pm
2 stops8h 19m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$270
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Tue 10/13
1:00 pm-10:45 pm
2 stops9h 45m
Manchester
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$279
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MHT Manchester
TYSMHT
Knoxville McGhee Tyson
Fri 10/16
6:05 pm-11:36 pm
1 stop5h 31m
Manchester
Sun 10/18
6:00 am-10:25 am
1 stop4h 25m
$398
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Manchester
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Manchester in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Manchester, New Hampshire flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Manchester, New Hampshire flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Manchester, New Hampshire flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Manchester
Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
TYS-MHT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Manchester
What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?
Currently, February is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $329). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $596). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Manchester, New Hampshire?
Airfare is below average for this route at the moment.
Knoxville to Manchester, New Hampshire flights typically cost between $368 and $426 in October.The cheapest round-trip price found within the last 5 days was $317 on American Airlines (Oct 15-Oct 20).
Reviews of airlines servicing Manchester
Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated September 24, 2026.
Read through reviews of airlines operating flights from Knoxville to Manchester, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Comfort
7.2
Food
6.4
Entertainment
6.8
Overall
7.0
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Boarding
7.4
Comfort
7.2
Food
6.4
Entertainment
6.8
Overall
7.0
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Manchester?
Book flights to Manchester if you plan to visit one of these locationsKeene
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Other flights to Manchester
Explore flights to Manchester departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 24, 2026.
Knoxville and Manchester flights
Browse other Knoxville and Manchester flight options. Last updated on September 24, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Manchester
Discover the top airline that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$310 | Average$401 | FlexibilityNo cancel fee | On-time71% |