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$185+ Cheap flights from Knoxville to Manchester, NH (TYS - MHT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MHT
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:32 am
TYS
-
MHT
1 stop4h 00m
American Airlines
Tue 6/95:41 am
MHT
-
TYS
1 stop5h 07m
American Airlines
Deal found 4/22$245
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:50 pm
TYS
-
MHT
2 stops9h 40m
Southwest
Tue 6/93:55 pm
MHT
-
TYS
1 stop5h 20m
Southwest
Deal found 4/22$251
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:32 am
TYS
-
MHT
1 stop4h 01m
American Airlines
Wed 6/175:41 am
MHT
-
TYS
1 stop5h 07m
American Airlines
Deal found 4/20$311
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:30 am
TYS
-
MHT
2 stops10h 33m
United Airlines
Wed 10/147:38 pm
MHT
-
TYS
1 stop4h 17m
United Airlines
Deal found 4/21$316
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:38 pm
TYS
-
MHT
1 stop5h 02m
American Airlines
Tue 5/124:42 pm
MHT
-
TYS
1 stop6h 14m
American Airlines
Deal found 4/23$337
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
TYS
-
MHT
1 stop10h 37m
American Airlines
Wed 5/205:44 am
MHT
-
TYS
1 stop10h 01m
American Airlines
Deal found 4/20$340
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:19 pm
TYS
-
MHT
1 stop4h 37m
United Airlines
Sat 8/227:38 pm
MHT
-
TYS
1 stop4h 19m
United Airlines
Deal found 4/23$350
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:02 am
TYS
-
MHT
1 stop5h 39m
American Airlines
Sun 9/206:02 am
MHT
-
TYS
1 stop4h 13m
American Airlines
Deal found 4/21$372
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:32 am
TYS
-
MHT
1 stop4h 01m
American Airlines
Wed 7/85:16 pm
MHT
-
TYS
1 stop4h 16m
American Airlines
Deal found 4/20$377
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:30 am
TYS
-
MHT
2 stops12h 32m
United Airlines
Sat 7/117:37 pm
MHT
-
TYS
1 stop4h 17m
United Airlines
Deal found 4/21$382
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:50 pm
TYS
-
MHT
2 stops9h 40m
Southwest
Wed 5/203:45 pm
MHT
-
TYS
1 stop5h 05m
Southwest
Deal found 4/20$386

Find flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$245
(American Airlines)

One-way from

$185
(American Airlines)

Popular in

July

Cheapest in

September

Average price

$492
Provider with most accurate pricing for Knoxville McGhee Tyson-Manchester flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Manchester flights.
Search Deals
From Knoxville McGhee Tyson to Manchester
Search Deals
One-way flight from Knoxville McGhee Tyson to Manchester
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Tue 6/2

12:50 pm-10:30 pm

2 stops9h 40m

Manchester

Tue 6/9

5:45 am-5:00 pm

2 stops11h 15m

$262
Quickest round-trip

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 9/30

9:45 am-2:08 pm

1 stop4h 23m

Manchester

Wed 10/14

7:38 pm-11:55 pm

1 stop4h 17m

$311

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 8/19

7:19 pm-11:56 pm

1 stop4h 37m

Manchester

Sat 8/22

7:38 pm-11:57 pm

1 stop4h 19m

$350

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Sat 7/4

6:30 am-7:02 pm

2 stops12h 32m

Manchester

Sat 7/11

7:37 pm-11:54 pm

1 stop4h 17m

$382

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 9/30

7:00 am-2:20 pm

2 stops7h 20m

Manchester

Wed 10/14

7:50 am-4:45 pm

2 stops8h 55m

$387

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 5/14

6:35 am-4:00 pm

2 stops9h 25m

Manchester

Sat 5/23

10:15 am-4:55 pm

1 stop6h 40m

$402

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Fri 5/8

12:15 pm-11:30 pm

2 stops11h 15m

Manchester

Tue 5/12

3:45 pm-8:50 pm

1 stop5h 05m

$416

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Mon 7/13

7:30 am-4:20 pm

1 stop8h 50m

Manchester

Fri 7/17

5:10 pm-10:30 pm

1 stop5h 20m

$422
Cheapest one-way

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Mon 5/11

6:38 pm-11:40 pm

1 stop5h 02m

$185

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Mon 5/11

1:15 pm-12:39 pm

2 stops47h 24m

$211

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Manchester

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Manchester in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Manchester, New Hampshire flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Manchester, New Hampshire flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Manchester, New Hampshire flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $218). Flying from Knoxville to Manchester, New Hampshire in July is currently the most expensive (average of $589). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Manchester, New Hampshire?

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated April 24, 2026.
Read through reviews of airlines operating flights from Knoxville to Manchester, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,666 reviews

Food

6.4

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

7.9

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,666 reviews
American Airlines
7.1
Good
11,666 reviews

Food

6.4

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

7.9

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester, New Hampshire?

    Departing from Knoxville to Manchester, New Hampshire will take you 4h 23m. The distance from Knoxville to Manchester, New Hampshire is about 830 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Manchester, New Hampshire round-trip?

    Flying on American Airlines is currently your cheapest option to Manchester, New Hampshire, with prices starting at $253. American Airlines is 36% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $218). Flying from Knoxville to Manchester, New Hampshire in July is currently the most expensive (average of $589). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Keene

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Top airline flying from Knoxville to Manchester

Discover the top airline that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$253Average$393FlexibilityNo cancel feeOn-time71%

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