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$199+ Cheap flights from Knoxville to Manchester, NH (TYS - MHT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MHT
ott 19 — ott 261
dom 10/19
dom 10/26
1 adult, Economy
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Cheap flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated settembre 19, 2025.

Round-trip from

$377
(American Airlines)

One-way from

$199
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$250
From Knoxville McGhee Tyson to Manchester
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One-way flight from Knoxville McGhee Tyson to Manchester
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Highest demand for flights based on searches. 17% potential increase in price ($105 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on settembre 19, 2025.

This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 10/175:37 pmTYS - MHT
1 stop6h 19mAmerican Airlines
dom 10/196:00 amMHT - TYS
1 stop4h 50mAmerican Airlines
Deal found 9/18$377
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 10/156:10 pmTYS - MHT
1 stop4h 47mAmerican Airlines
sab 10/185:45 amMHT - TYS
1 stop4h 28mAmerican Airlines
Deal found 9/17$402
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 10/175:37 pmTYS - MHT
1 stop6h 19mAmerican Airlines
lun 10/205:10 pmMHT - TYS
1 stop6h 40mAmerican Airlines
Deal found 9/17$438
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 9/276:25 amTYS - MHT
1 stop5h 13mAmerican Airlines
mer 10/18:00 amMHT - TYS
1 stop6h 09mAmerican Airlines
Deal found 9/18$442
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 9/309:55 amTYS - MHT
1 stop5h 07mUnited Airlines
ven 10/109:40 amMHT - TYS
1 stop5h 05mUnited Airlines
Deal found 9/17$472
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 9/309:55 amTYS - MHT
1 stop5h 07mUnited Airlines
dom 10/129:40 amMHT - TYS
2 stops13h 10mUnited Airlines
Deal found 9/17$477

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated settembre 19, 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

mer 10/15

5:00 am-11:22 am

1 stop6h 22m

Manchester

sab 10/18

5:45 am-10:13 am

1 stop4h 28m

$402

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

sab 10/4

9:55 am-3:02 pm

1 stop5h 07m

Manchester

sab 10/11

9:40 am-2:45 pm

1 stop5h 05m

$472

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

sab 10/4

9:55 am-3:02 pm

1 stop5h 07m

Manchester

ven 10/10

9:40 am-2:45 pm

1 stop5h 05m

$472

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

mar 9/30

9:55 am-3:02 pm

1 stop5h 07m

Manchester

mer 10/8

9:40 am-2:45 pm

1 stop5h 05m

$472

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

mer 10/1

9:55 am-3:02 pm

1 stop5h 07m

Manchester

sab 10/11

9:40 am-2:45 pm

1 stop5h 05m

$472

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

mer 10/1

7:00 am-3:02 pm

2 stops8h 02m

Manchester

mer 10/8

9:40 am-2:45 pm

1 stop5h 05m

$477

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

mer 10/1

7:00 am-3:02 pm

2 stops8h 02m

Manchester

dom 10/12

9:40 am-2:45 pm

1 stop5h 05m

$477

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

mer 10/1

7:00 am-3:02 pm

2 stops8h 02m

Manchester

ven 10/10

9:40 am-10:50 pm

2 stops13h 10m

$482

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

ven 10/17

4:18 pm-11:05 pm

1 stop6h 47m

$199

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

ven 10/17

8:54 pm-6:56 pm

2 stops22h 02m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/18

Showing 1-10 of 13 results
1
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Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $334). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated settembre 19, 2025.
Read through reviews of airlines operating flights from Knoxville to Manchester, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,926 reviews

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester, New Hampshire?

    Departing from Knoxville to Manchester, New Hampshire will take you 5h 07m. The distance from Knoxville to Manchester, New Hampshire is about 830 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Manchester, New Hampshire round-trip?

    Flying on United Airlines is currently your cheapest option to Manchester, New Hampshire, with prices starting at $250. Another option worth looking into is American Airlines, starting at $253 round trip. United Airlines is 49% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $334). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Keene

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Top 2 airlines flying from Knoxville to Manchester

Discover the top 2 airlines that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated settembre 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$250Average$329FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$253Average$461FlexibilityNo cancel feeOn-time71%

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