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$236+ Cheap flights from Knoxville to Manchester, NH (TYS - MHT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MHT
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 20, 2025.

Round-trip from

$249
(American Airlines)

One-way from

$236
(Mytrip)

Popular in

December

Cheapest in

June

Average price

$393
From Knoxville McGhee Tyson to Manchester
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One-way flight from Knoxville McGhee Tyson to Manchester
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Highest demand for flights based on searches. 24% potential increase in price ($170 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:03 amTYS - MHT
1 stop6h 19mAmerican Airlines
Sat 11/17:07 amMHT - TYS
1 stop5h 24mAmerican Airlines
Deal found 8/20$249
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/275:27 pmTYS - MHT
1 stop6h 32mAmerican Airlines
Thu 9/46:00 amMHT - TYS
1 stop4h 37mAmerican Airlines
Deal found 8/18$284
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:00 amTYS - MHT
2 stops7h 57mUnited Airlines
Thu 9/49:40 amMHT - TYS
1 stop5h 00mUnited Airlines
Deal found 8/18$289
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:08 pmTYS - MHT
1 stop6h 43mAmerican Airlines
Wed 11/54:09 pmMHT - TYS
2 stops6h 42mAmerican Airlines
Deal found 8/18$306
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:10 pmTYS - MHT
1 stop4h 52mAmerican Airlines
Thu 9/2511:57 amMHT - TYS
1 stop5h 46mAmerican Airlines
Deal found 8/19$314
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/29:55 amTYS - MHT
1 stop5h 02mUnited Airlines
Sat 9/69:40 amMHT - TYS
1 stop5h 00mUnited Airlines
Deal found 8/18$329
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/212:03 pmTYS - MHT
2 stops9h 10mAmerican Airlines
Sat 9/612:08 pmMHT - TYS
2 stops8h 52mAmerican Airlines
Deal found 8/18$330
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2310:36 amTYS - MHT
1 stop6h 12mAmerican Airlines
Mon 8/256:00 amMHT - TYS
1 stop4h 29mAmerican Airlines
Deal found 8/19$339

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Sat 10/25

6:03 am-12:22 pm

1 stop6h 19m

Manchester

Sat 11/1

7:07 am-12:31 pm

1 stop5h 24m

$249

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Fri 10/31

5:08 pm-11:51 pm

1 stop6h 43m

Manchester

Wed 11/5

4:09 pm-9:04 pm

1 stop4h 55m

$249

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 8/27

5:27 pm-11:59 pm

1 stop6h 32m

Manchester

Thu 9/4

6:00 am-10:37 am

1 stop4h 37m

$284

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 8/27

7:00 am-2:57 pm

2 stops7h 57m

Manchester

Thu 9/4

9:40 am-2:40 pm

1 stop5h 00m

$289

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 9/18

6:10 pm-11:02 pm

1 stop4h 52m

Manchester

Thu 9/25

11:57 am-5:43 pm

1 stop5h 46m

$314

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Tue 9/2

9:55 am-2:57 pm

1 stop5h 02m

Manchester

Sat 9/6

9:40 am-2:40 pm

1 stop5h 00m

$329

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Tue 9/2

12:03 pm-9:13 pm

2 stops9h 10m

Manchester

Sat 9/6

12:08 pm-9:00 pm

2 stops8h 52m

$330

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 10/16

4:03 pm-10:00 am

2 stops17h 57m

$236

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 10/16

4:18 pm-11:05 pm

1 stop6h 47m

$239

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Tue 9/30

2:34 pm-8:57 pm

1 stop6h 23m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 17 results
1
2

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $334). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated August 20, 2025.
Read through reviews of airlines operating flights from Knoxville to Manchester, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Overall

7.4

Food

6.6

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,928 reviews
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Overall

7.4

Food

6.6

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Overall

7.4

Food

6.6

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester, New Hampshire?

    Departing from Knoxville to Manchester, New Hampshire will take you 6h 19m. The distance from Knoxville to Manchester, New Hampshire is about 830 mi.

  • What are the cheapest airlines flying from Knoxville to Manchester, New Hampshire round-trip?

    Flying on United Airlines is currently your cheapest option to Manchester, New Hampshire, with prices starting at $250. Another option worth looking into is American Airlines, starting at $253 round trip. United Airlines is 53% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $334). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Keene

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Top 2 airlines flying from Knoxville to Manchester

Discover the top 2 airlines that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$250Average$329FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$253Average$494FlexibilityNo cancel feeOn-time71%

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