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$304+ Cheap flights from Knoxville to Manchester, NH (TYS - MHT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MHT
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/152:30 pmTYS - MHT
1 stop4h 19mUnited Airlines
Mon 12/222:23 pmMHT - TYS
1 stop5h 28mUnited Airlines
Deal found 11/17$377
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:45 amTYS - MHT
2 stops12h 06mUnited Airlines
Thu 12/257:26 pmMHT - TYS
1 stop4h 33mUnited Airlines
Deal found 11/19$380
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:06 amTYS - MHT
2 stops8h 37mAmerican Airlines
Sun 12/214:40 pmMHT - TYS
1 stop7h 07mAmerican Airlines
Deal found 11/18$382
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:38 pmTYS - MHT
2 stops7h 19mAmerican Airlines
Mon 12/224:15 pmMHT - TYS
1 stop4h 28mAmerican Airlines
Deal found 11/17$443
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:30 pmTYS - MHT
1 stop4h 19mUnited Airlines
Tue 12/92:32 pmMHT - TYS
1 stop4h 57mUnited Airlines
Deal found 11/20$452
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:05 amTYS - MHT
1 stop6h 35mAmerican Airlines
Mon 12/84:07 pmMHT - TYS
1 stop6h 48mAmerican Airlines
Deal found 11/18$457
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:51 pmTYS - MHT
1 stop5h 01mAmerican Airlines
Mon 12/811:32 amMHT - TYS
1 stop4h 34mAmerican Airlines
Deal found 11/19$543
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:44 amTYS - MHT
2 stops9h 06mAmerican Airlines
Thu 12/2511:37 amMHT - TYS
2 stops8h 04mAmerican Airlines
Deal found 11/19$568

Cheap flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$353
(American Airlines)

One-way from

$304
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$378
Provider with most accurate pricing for Knoxville McGhee Tyson-Manchester flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Manchester flights.
Search Deals
From Knoxville McGhee Tyson to Manchester
Search Deals
One-way flight from Knoxville McGhee Tyson to Manchester
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($174 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Sat 1/3

5:42 am-11:11 am

1 stop5h 29m

Manchester

Tue 1/6

5:30 am-10:49 am

1 stop5h 19m

$353

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 2/12

5:49 am-10:26 am

1 stop4h 37m

Manchester

Sun 2/15

5:23 am-11:15 am

1 stop5h 52m

$357

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Mon 2/2

6:00 am-11:35 am

1 stop5h 35m

Manchester

Thu 2/5

5:30 am-1:54 pm

2 stops8h 24m

$362

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Mon 12/15

2:30 pm-6:49 pm

1 stop4h 19m

Manchester

Mon 12/22

2:23 pm-7:51 pm

1 stop5h 28m

$377

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 12/18

6:25 pm-10:56 pm

1 stop4h 31m

Manchester

Thu 12/25

11:37 am-6:07 pm

1 stop6h 30m

$377

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 12/17

4:59 pm-11:57 pm

1 stop6h 58m

Manchester

Sun 12/21

4:15 pm-8:43 pm

1 stop4h 28m

$377

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Fri 11/28

7:35 am-11:55 am

1 stop4h 20m

$304

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Fri 11/28

7:15 am-5:45 pm

3 stops34h 30m

$612

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Compare providers for flights from Knoxville to Manchester

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Manchester in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Manchester, New Hampshire flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Manchester, New Hampshire flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Manchester, New Hampshire flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Manchester, New Hampshire flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

Currently, July is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $63). Flying from Knoxville to Manchester, New Hampshire in January is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated November 20, 2025.
Read through reviews of airlines operating flights from Knoxville to Manchester, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,028 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Crew

8.1

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,028 reviews
United Airlines
7.4
Good
9,028 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Crew

8.1

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,047 reviews
United Airlines
7.4
Good
9,028 reviews

Food

6.6

Overall

7.4

Boarding

7.7

Crew

8.1

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester, New Hampshire?

    Departing from Knoxville to Manchester, New Hampshire will take you 5h 29m. The distance from Knoxville to Manchester, New Hampshire is about 830 mi.

  • What are the cheapest airlines flying from Knoxville to Manchester, New Hampshire round-trip?

    Flying on United Airlines is currently your cheapest option to Manchester, New Hampshire, with prices starting at $250. Another option worth looking into is American Airlines, starting at $253 round trip. United Airlines is 43% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

    Currently, July is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $63). Flying from Knoxville to Manchester, New Hampshire in January is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Keene

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Top 2 airlines flying from Knoxville to Manchester

Discover the top 2 airlines that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$250Average$329FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$253Average$410FlexibilityNo cancel feeOn-time71%

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