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$594+ Cheap flights from Panama to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Jul 27 — Aug 31
Mon 7/27
Mon 8/3
1 adult, Economy
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Cheap flight deals from Panama to Madrid

Cheapest flights from Panama to Madrid
Explore the most affordable flight options available from Panama to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.

This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:45 am
PTY
-
MAD
2 stops38h 05m
United Airlines
Thu 11/51:35 pm
MAD
-
PTY
2 stops36h 27m
United Airlines
Deal found 6/24$778
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:45 am
PTY
-
MAD
2 stops38h 05m
United Airlines
Thu 10/2911:15 am
MAD
-
PTY
2 stops32h 30m
United Airlines
Deal found 6/26$779
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:30 pm
PTY
-
MAD
2 stops33h 35m
United Airlines
Fri 8/2812:45 pm
MAD
-
PTY
2 stops22h 19m
United Airlines
Deal found 6/23$780
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:30 pm
PTY
-
MAD
2 stops34h 15m
United Airlines
Mon 11/211:15 am
MAD
-
PTY
2 stops33h 30m
United Airlines
Deal found 6/23$781
This KLM deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:20 pm
PTY
-
MAD
1 stop14h 55m
Multiple Airlines
Mon 8/316:00 am
MAD
-
PTY
2 stops20h 45m
Multiple Airlines
Deal found 6/26$782
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm
PTY
-
MAD
2 stops33h 35m
United Airlines
Thu 10/151:30 pm
MAD
-
PTY
2 stops31h 44m
United Airlines
Deal found 6/25$784
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:55 pm
PTY
-
MAD
2 stops26h 10m
United Airlines
Wed 8/196:20 am
MAD
-
PTY
2 stops28h 44m
United Airlines
Deal found 6/25$785
This Iberia deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:05 pm
PTY
-
MAD
Nonstop10h 05m
Iberia
Wed 11/412:00 pm
MAD
-
PTY
Nonstop11h 05m
Iberia
Deal found 6/25$786
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:45 am
PTY
-
MAD
1 stop16h 15m
United Airlines
Mon 9/286:20 am
MAD
-
PTY
2 stops20h 11m
United Airlines
Deal found 6/23$787
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:55 pm
PTY
-
MAD
2 stops26h 10m
United Airlines
Wed 9/236:20 am
MAD
-
PTY
2 stops20h 11m
United Airlines
Deal found 6/22$788
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:45 am
PTY
-
MAD
1 stop16h 15m
United Airlines
Wed 9/306:20 am
MAD
-
PTY
2 stops20h 11m
United Airlines
Deal found 6/27$789

Find flight deals from Panama to Madrid

Keep the following information in mind while searching for Panama to Madrid flight deals. Data was last updated June 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$778
(United Airlines)

One-way from

$594
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$894

Good round-trip deal

$904 or less

Good one-way deal

$689 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Madrid Barajas flights.
Search Deals
From Panama to Madrid Barajas
Search Deals
One-way flight from Panama to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Panama to Madrid Barajas.
Search Deals
Price to beat on a one-way flight from Panama to Madrid Barajas.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Panama to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 10/14

9:45 am-6:50 am

2 stops38h 05m

Madrid Barajas

Fri 10/30

11:00 am-1:45 pm

2 stops32h 45m

$780

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 8/29

3:30 pm-9:00 am

2 stops34h 30m

Madrid Barajas

Sat 9/19

12:45 pm-7:31 pm

2 stops37h 46m

$780

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 11/2

4:41 pm-9:15 am

2 stops34h 34m

Madrid Barajas

Sat 11/14

11:15 am-2:45 pm

2 stops33h 30m

$781

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 8/18

3:30 pm-9:00 am

2 stops34h 30m

Madrid Barajas

Wed 3/31

11:15 am-2:14 pm

2 stops33h 59m

$781

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 7/25

9:45 am-9:00 am

1 stop16h 15m

Madrid Barajas

Mon 8/17

5:55 am-4:04 am

2 stops29h 09m

$798

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 10/2

9:45 am-6:50 am

2 stops38h 05m

Madrid Barajas

Fri 10/16

6:00 am-7:31 pm

2 stops20h 31m

$801

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 9/2

9:45 am-4:45 pm

2 stops24h 00m

Madrid Barajas

Tue 9/15

10:50 am-2:14 pm

2 stops34h 24m

$803

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 8/8

2:30 pm-12:15 pm

1 stop14h 45m

Madrid Barajas

Fri 8/28

6:00 am-7:45 pm

2 stops20h 45m

$804
Quickest round-trip

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 10/2

9:45 am-9:00 am

1 stop16h 15m

Madrid Barajas

Thu 10/15

10:50 am-7:31 pm

1 stop15h 41m

$822

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 11/27

10:00 am-9:15 am

1 stop17h 15m

Madrid Barajas

Fri 12/11

11:15 am-5:12 pm

2 stops35h 57m

$823

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/26

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Madrid

What is the cheapest month to book a flight from Panama to Madrid?

Currently, July is the cheapest month in which you can book a flight from Panama to Madrid (average of $699). Flying from Panama to Madrid in August is currently the most expensive (average of $1,327). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to MAD?

Find hourly flight availability from Panama to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 27, 2026.

When flying from Panama to Madrid, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Panama to Madrid

Explore weekly flight availability from Panama to Madrid. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 27, 2026.

The most flights from PA0 to MAD are scheduled on a Wednesday (11 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (5 on average).

How often are flights from Panama to Madrid delayed?

About 11% of weekly flights between Panama and Madrid have experienced delays in the past year, with the average delay time being 146 minutes.

What is the most punctual flight time for Panama to Madrid flights?

Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Sunday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama to Madrid flights?

Over the last year, Air Europa have had the lowest number of delays on this route, with just 10% of flights being delayed.

How far ahead should I book a flight from Panama to Madrid?

The best time to book flights from Panama to Madrid is 90 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated June 27, 2026.
Get a feel of what it's like to fly with Copa Airlines,Air France, andAir Europa from Panama to Madrid by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,569 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.6

Entertainment

6.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.6
Good
1,569 reviews
Copa Airlines
7.6
Good
1,569 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.6

Entertainment

6.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Air France
7.5
Good
1,614 reviews
Copa Airlines
7.6
Good
1,569 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.6

Entertainment

6.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Air Europa
7.0
Good
622 reviews
Copa Airlines
7.6
Good
1,569 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.6

Entertainment

6.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Iberia
7.0
Good
3,250 reviews
Copa Airlines
7.6
Good
1,569 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.6

Entertainment

6.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Avianca
6.5
Okay
2,536 reviews
Copa Airlines
7.6
Good
1,569 reviews

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.6

Entertainment

6.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Panama to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Madrid from Panama?

    Madrid Barajas (MAD), located 8.5 mi from the city center, is the airport you fly into when you book flights from Panama to Madrid.

  • How popular is this Panama to Madrid flight route?

    This flight path from Panama to Madrid Barajas was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Panama to Madrid?

    For as low as $778, United Airlines can have you in Madrid from Panama in 24h 55m. Airlines will cover a distance of 5065 mi.

  • What are the cheapest airlines to fly from Panama to Madrid one-way?

    $508 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Air Europa and Copa Airlines, with prices starting from $518 and $602, respectively.

  • What are the most reliable airlines from Panama to Madrid?

    Consider Air Europa (90%), Etihad Airways (90%) or China Eastern (90%) when booking your flight. These represent the most reliable airlines when flying from Panama to Madrid.

  • What are the cheapest flights from Panama to Madrid?

    On average you can expect to pay $1,608 for a flight from Panama to Madrid. The cheapest flight overall is $656 while the most popular route, (Panama City Tocumen Intl - Madrid Barajas) is currently priced at $703.

  • Can I find deals for flights from Panama to Madrid that include hotel bookings?

    Yes. In addition to deals on Panama to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Madrid.

  • Can I find deals for business class flights from Panama to Madrid?

    Yes. Cheapflights offers flight deals from Panama to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Madrid?

    Currently, July is the cheapest month in which you can book a flight from Panama to Madrid (average of $699). Flying from Panama to Madrid in August is currently the most expensive (average of $1,327). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

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Alternative routes for Panama to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
San José to Madrid flights
Panama City to Madrid flights
Guatemala City to Madrid flights
San Salvador to Madrid flights
San Pedro Sula to Madrid flights
Managua to Madrid flights

Top 8 airlines flying from Panama to Madrid

Discover the top 8 airlines that operate flights from Panama to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$618Average$798FlexibilityNo cancel feeOn-time75%
AviancaCheapest$623Average$743FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$644Average$783FlexibilityNo cancel feeOn-time77%
IberiaCheapest$669Average$867FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$672Average$880FlexibilityNo cancel feeOn-time83%
Turkish AirlinesCheapest$698Average$762FlexibilityNo cancel feeOn-time77%
Copa AirlinesCheapest$722Average$1,269FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$767Average$848FlexibilityNo cancel feeOn-time69%

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