$515+ Cheap flights from Panama to Madrid, Spain (MAD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama to MadridExplore the most affordable flight options available from Panama to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Panama to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:55 pm -
1 stop27h 35m
Sun 1/2411:15 am -
2 stops33h 30m
Deal found 11/9![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:55 pm -
1 stop27h 35m
Sun 1/171:25 pm -
2 stops36h 37m
Deal found 11/6![United Airlines logo]()
$771
This KLM deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:55 pm -
1 stop15h 40m
Thu 8/268:30 pm -
1 stop27h 20m
Deal found 11/9![KLM logo]()
$779
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:41 pm -
2 stops33h 04m
Sat 1/161:25 pm -
2 stops36h 37m
Deal found 11/8![United Airlines logo]()
$780
This KLM deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop15h 20m
Mon 1/186:00 am -
1 stop20h 20m
Deal found 11/4![Multiple Airlines logo]()
$786
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:00 am -
2 stops25h 50m
Wed 12/911:00 am -
2 stops39h 02m
Deal found 11/4![United Airlines logo]()
$790
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:00 am -
2 stops19h 45m
Fri 12/1111:00 am -
2 stops38h 38m
Deal found 11/4![United Airlines logo]()
$794
This Avianca deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:10 pm -
1 stop23h 15m
Thu 2/48:10 am -
1 stop15h 05m
Deal found 11/5![Avianca logo]()
$804
This KLM deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop22h 50m
Wed 11/256:00 am -
1 stop20h 20m
Deal found 11/5![Multiple Airlines logo]()
$805
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:55 am -
2 stops25h 25m
Sat 12/1211:00 am -
2 stops39h 02m
Deal found 11/5![United Airlines logo]()
$811
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:55 pm -
1 stop27h 35m
Thu 8/2610:50 am -
2 stops34h 24m
Deal found 11/9![United Airlines logo]()
$814
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:41 pm -
2 stops33h 04m
Wed 3/1011:15 am -
2 stops33h 30m
Deal found 11/7![United Airlines logo]()
$817
Best flights from Panama to MadridDiscover carefully curated flight deals from Panama to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Panama to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:00 am -
1 stop17h 30m
Wed 12/911:00 am -
2 stops33h 45m
Deal found 11/4![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/198:55 am -
2 stops18h 35m
Sun 1/3111:15 am -
2 stops33h 30m
Deal found 11/5![United Airlines logo]()
$773
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/14:41 pm -
2 stops34h 49m
Thu 4/2911:15 am -
2 stops33h 59m
Deal found 11/4![United Airlines logo]()
$773
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/510:00 am -
1 stop17h 30m
Sun 2/141:25 pm -
2 stops33h 47m
Deal found 11/4![United Airlines logo]()
$776
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:41 pm -
2 stops33h 04m
Sat 1/161:25 pm -
2 stops36h 37m
Deal found 11/8![United Airlines logo]()
$780
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:00 am -
2 stops19h 45m
Fri 12/1111:00 am -
2 stops38h 38m
Deal found 11/4![United Airlines logo]()
$794
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:35 am -
2 stops38h 10m
Thu 2/41:25 pm -
2 stops36h 37m
Deal found 11/6![United Airlines logo]()
$827
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:00 am -
1 stop17h 30m
Thu 12/1011:15 am -
2 stops33h 30m
Deal found 11/6![United Airlines logo]()
$884
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
1 stop17h 30m
Sat 12/2611:00 am -
2 stops33h 45m
Deal found 11/6![United Airlines logo]()
$884
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:16 am -
2 stops17h 29m
Mon 12/1411:00 am -
2 stops38h 38m
Deal found 11/7![United Airlines logo]()
$950
Last-minute flights from Panama to MadridDiscover last-minute flight deals from Panama to Madrid. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Madrid. Data last updated November 9, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop15h 20m
Mon 1/186:00 am -
1 stop20h 20m
Deal found 11/4![Multiple Airlines logo]()
$786
This KLM deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop22h 50m
Wed 11/256:00 am -
1 stop20h 20m
Deal found 11/5![Multiple Airlines logo]()
$805
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:00 am -
2 stops25h 50m
Wed 12/911:00 am -
2 stops39h 02m
Deal found 11/4![United Airlines logo]()
$790
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:00 am -
2 stops19h 45m
Fri 12/1111:00 am -
2 stops38h 38m
Deal found 11/4![United Airlines logo]()
$794
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:55 am -
2 stops25h 25m
Sat 12/1211:00 am -
2 stops39h 02m
Deal found 11/5![United Airlines logo]()
$811
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:41 pm -
2 stops33h 04m
Wed 3/1011:15 am -
2 stops33h 30m
Deal found 11/7![United Airlines logo]()
$817
This KLM deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:55 pm -
1 stop15h 40m
Thu 8/268:30 pm -
1 stop27h 20m
Deal found 11/9![KLM logo]()
$779
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2711:55 pm -
1 stop27h 35m
Thu 8/2610:50 am -
2 stops34h 24m
Deal found 11/9![United Airlines logo]()
$814
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:55 pm -
1 stop27h 35m
Sun 1/2411:15 am -
2 stops33h 30m
Deal found 11/9![United Airlines logo]()
$768
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:55 pm -
1 stop27h 35m
Tue 1/191:25 pm -
2 stops33h 47m
Deal found 11/6![United Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:41 pm -
2 stops33h 04m
Sat 1/161:25 pm -
2 stops36h 37m
Deal found 11/8![United Airlines logo]()
$780
This Avianca deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:10 pm -
1 stop23h 15m
Thu 2/48:10 am -
1 stop15h 05m
Deal found 11/5![Avianca logo]()
$804
One-way flights from Panama to MadridSearch for one-way flight options from Panama to Madrid. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Panama to Madrid. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Air Europa logo]()
$515
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Air Europa logo]()
$524
This deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Air Europa logo]()
$540
This KLM deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:45 pm -
1 stop22h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![KLM logo]()
$612
This KLM deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop18h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![KLM logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/299:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Air Europa logo]()
$623
This KLM deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/299:55 pm -
1 stop19h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![KLM logo]()
$625
This FlightHub deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:44 pm -
2 stops27h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$638
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/279:30 pm -
Nonstop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Air Europa logo]()
$644
This Avianca deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/62:30 am -
1 stop23h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Avianca logo]()
$647
This Air France deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
2 stops18h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Air France logo]()
$649
Find flight deals from Panama to Madrid
Keep the following information in mind while searching for Panama to Madrid flight deals. Data was last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $768 (United Airlines) |
One-way from | $515 (Kiwi.com) |
Popular in | December |
Cheapest in | February |
Average price | $821 |
Good round-trip deal | $944 or less |
Good one-way deal | $645 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Panama to Madrid that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Mon 11/16
6:45 pm-7:35 pm
1 stop18h 50m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Sat 11/14
6:45 pm-11:35 pm
1 stop22h 50m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Sun 11/22
6:45 pm-11:35 pm
1 stop22h 50m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Thu 12/24
6:45 pm-11:35 pm
1 stop22h 50m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Wed 11/25
6:45 pm-7:35 pm
1 stop18h 50m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$617
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Wed 11/25
12:44 pm-9:45 pm
2 stops27h 01m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$638
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Thu 12/17
10:05 am-8:10 am
1 stop16h 05m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$649
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Thu 11/19
10:30 pm-11:35 pm
2 stops19h 05m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$649
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Sun 1/31
9:55 pm-7:35 pm
1 stop15h 40m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$678
Panama CityMadrid
PTY Panama City Tocumen Intl - MAD Madrid Barajas
PTYMAD
Panama City Tocumen Intl
Thu 2/4
6:45 pm-11:35 pm
1 stop22h 50m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$678
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Panama to Madrid
Have a flexible travel schedule? Discover the best time to fly to Madrid from Panama with our price prediction graph.
PTY-MAD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Madrid
PA0-MAD
PTY-MAD
What is the cheapest month to book a flight from Panama to Madrid?
Currently, February is the cheapest month in which you can book a flight from Panama to Madrid (average of $763). Flying from Panama to Madrid in December is currently the most expensive (average of $974). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to MAD?
Find hourly flight availability from Panama to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 9, 2026.
When flying from Panama to Madrid, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Panama to Madrid
Explore weekly flight availability from Panama to Madrid. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 9, 2026.
The most flights from PA0 to MAD are scheduled on a Wednesday (10 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (5 on average).
How often are flights from Panama to Madrid delayed?
About 13% of weekly flights between Panama and Madrid have experienced delays in the past year, with the average delay time being 153 minutes.
What is the most punctual flight time for Panama to Madrid flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama to Madrid flights?
Over the last year, Air Europa have had the lowest number of delays on this route, with just 10% of flights being delayed.
How far ahead should I book a flight from Panama to Madrid?
The best time to book flights from Panama to Madrid is 90 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Madrid
Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated November 9, 2026.
Get a feel of what it's like to fly with Air France,United Airlines, andAir Europa from Panama to Madrid by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Overall
7.5
Entertainment
7.0
Food
7.1
Crew
8.2
Comfort
7.4
Reviews
1 / 20
8.0
ExcellentCarmen,Jul 2026
ATH - JFK
Boarding
7.5
Overall
7.5
Entertainment
7.0
Food
7.1
Crew
8.2
Comfort
7.4
Reviews
1 / 20
8.0
ExcellentCarmen,Jul 2026
ATH - JFK
Boarding
7.5
Overall
7.5
Entertainment
7.0
Food
7.1
Crew
8.2
Comfort
7.4
Reviews
1 / 20
8.0
ExcellentCarmen,Jul 2026
ATH - JFK
Boarding
7.5
Overall
7.5
Entertainment
7.0
Food
7.1
Crew
8.2
Comfort
7.4
Reviews
1 / 20
8.0
ExcellentCarmen,Jul 2026
ATH - JFK
Boarding
7.5
Overall
7.5
Entertainment
7.0
Food
7.1
Crew
8.2
Comfort
7.4
Reviews
1 / 20
8.0
ExcellentCarmen,Jul 2026
ATH - JFK
Boarding
7.5
Overall
7.5
Entertainment
7.0
Food
7.1
Crew
8.2
Comfort
7.4
Reviews
1 / 20
8.0
ExcellentCarmen,Jul 2026
ATH - JFK
Related info for your journey
Find useful and relevant information for your journey from Panama to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Book flights to Madrid if you plan to visit one of these locationsGetafe
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Top 8 airlines flying from Panama to Madrid
Discover the top 8 airlines that operate flights from Panama to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$567 | Average$964 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$603 | Average$951 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$658 | Average$750 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$673 | Average$910 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$681 | Average$761 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$696 | Average$905 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$767 | Average$838 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$1,292 | Average$1,347 | FlexibilityNo cancel fee | On-time70% |