$356+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Sep 22 — Sep 291
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Madrid with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Madrid
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Best
Last-minute
One-way
Cheapest flights from Knoxville to MadridExplore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/812:42 pm -
1 stop14h 13m
Tue 12/151:15 pm -
1 stop13h 34m
Deal found 8/19![British Airways logo]()
$709
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:33 am -
1 stop15h 17m
Tue 12/156:05 pm -
2 stops35h 42m
Deal found 8/19![Iberia logo]()
$721
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:35 pm -
2 stops22h 00m
Tue 12/151:25 pm -
2 stops31h 17m
Deal found 8/19![Multiple Airlines logo]()
$724
This Virgin Atlantic deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:40 pm -
1 stop13h 05m
Wed 12/1612:20 pm -
1 stop13h 49m
Deal found 8/19![Virgin Atlantic logo]()
$729
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:30 am -
2 stops17h 15m
Wed 12/1611:15 am -
1 stop15h 39m
Deal found 8/19![United Airlines logo]()
$731
This oojo deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:35 pm -
2 stops16h 15m
Mon 11/166:35 pm -
2 stops56h 19m
Deal found 8/19![Lufthansa logo]()
$738
This Finnair deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:50 am -
1 stop19h 00m
Mon 11/169:40 pm -
2 stops30h 04m
Deal found 8/19![Multiple Airlines logo]()
$745
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:45 am -
2 stops21h 30m
Mon 11/161:20 pm -
2 stops40h 39m
Deal found 8/22![United Airlines logo]()
$756
This oojo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:31 am -
1 stop16h 04m
Wed 12/212:40 pm -
1 stop16h 08m
Deal found 8/18![British Airways logo]()
$759
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:40 pm -
2 stops56h 20m
Fri 11/276:05 am -
2 stops23h 54m
Deal found 8/19![United Airlines logo]()
$762
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
2 stops18h 50m
Fri 10/2312:45 pm -
2 stops34h 23m
Deal found 8/19![United Airlines logo]()
$764
Best flights from Knoxville to MadridDiscover carefully curated flight deals from Knoxville to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
Discover carefully curated flight deals from Knoxville to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/174:16 pm -
1 stop10h 59m
Thu 1/216:05 am -
2 stops19h 12m
Deal found 8/21![United Airlines logo]()
$759
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:45 am -
2 stops21h 30m
Wed 12/211:15 am -
2 stops28h 44m
Deal found 8/18![United Airlines logo]()
$765
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:16 pm -
1 stop10h 44m
Sun 10/2511:00 am -
1 stop17h 59m
Deal found 8/19![United Airlines logo]()
$781
Last-minute flights from Knoxville to MadridDiscover last-minute flight deals from Knoxville to Madrid. Data last updated August 23, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Madrid. Data last updated August 23, 2026 and is based on user searches.
This British Airways deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:30 am -
1 stop17h 05m
Sun 10/113:20 pm -
1 stop32h 15m
Deal found 8/19![British Airways logo]()
$872
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
2 stops20h 50m
Sun 10/1111:15 am -
2 stops28h 30m
Deal found 8/19![United Airlines logo]()
$873
This Air Canada deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:45 am -
3 stops17h 05m
Sun 10/1112:45 pm -
2 stops27h 00m
Deal found 8/22![Multiple Airlines logo]()
$1,393
This Air Canada deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:45 am -
3 stops17h 05m
Sun 10/1112:45 pm -
3 stops17h 14m
Deal found 8/22![Air Canada logo]()
$2,180
One-way flights from Knoxville to MadridSearch for one-way flight options from Knoxville to Madrid. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
Search for one-way flight options from Knoxville to Madrid. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
This oojo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:12 pm -
1 stop31h 33m
Deal found 8/18![British Airways logo]()
$356
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:39 pm -
2 stops33h 36m
Deal found 8/18![United Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:39 pm -
3 stops57h 51m
Deal found 8/19![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:34 am -
2 stops36h 46m
Deal found 8/20![Multiple Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:45 am -
1 stop16h 20m
Deal found 8/20![United Airlines logo]()
$513
This Air Canada deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:45 am -
3 stops16h 15m
Deal found 8/21![Air Canada logo]()
$522
Find flight deals from Knoxville to Madrid
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 23, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $709 (Expedia) |
One-way from | $356 (oojo) |
Popular in | June |
Cheapest in | December |
Average price | $1,036 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 1/17
4:16 pm-9:15 am
1 stop10h 59m
Madrid Barajas
Thu 1/21
6:05 am-7:17 pm
2 stops19h 12m
$759
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 11/1
5:45 am-9:15 am
2 stops21h 30m
Madrid Barajas
Wed 12/2
11:15 am-9:59 am
2 stops28h 44m
$765
Quickest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Wed 10/14
4:16 pm-9:00 am
1 stop10h 44m
Madrid Barajas
Sun 10/25
11:00 am-11:59 pm
1 stop17h 59m
$781
Cheapest one-way
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
4:12 pm-5:45 am
1 stop31h 33m
$356
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
7:35 pm-9:15 am
2 stops31h 40m
$367
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Fri 10/2
5:39 pm-9:30 am
3 stops57h 51m
$409
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Thu 9/24
11:34 am-6:20 am
2 stops36h 46m
$490
Quickest one-way
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Fri 10/2
9:45 am-8:05 am
1 stop16h 20m
$513
Sorted by cheapest first
Compare providers for flights from Knoxville to Madrid
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Madrid
Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
TYS-MAD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Madrid
Reviews of airlines servicing Madrid
Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated August 23, 2026.
See what other customers who have flown with American Airlines from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Boarding
7.5
Crew
7.9
Comfort
7.2
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Aug 2025
BNA - ORD
Overall
7.1
Boarding
7.5
Crew
7.9
Comfort
7.2
Food
6.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Aug 2025
BNA - ORD
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Madrid?
Book flights to Madrid if you plan to visit one of these locationsGetafe
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Other flights to Madrid
Explore flights to Madrid departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 23, 2026.
Knoxville and Madrid flights
Browse other Knoxville and Madrid flight options. Last updated on August 23, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on August 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Madrid
Discover the top 2 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$591 | Average$822 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$677 | Average$1,049 | FlexibilityNo cancel fee | On-time71% |