$340+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Nov 20 — Nov 271
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Madrid with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Madrid
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MadridExplore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:07 pm -
1 stop11h 38m
Tue 12/81:25 pm -
2 stops37h 12m
Deal found 10/17![United Airlines logo]()
$739
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:34 am -
1 stop15h 16m
Tue 12/810:00 am -
1 stop18h 10m
Deal found 10/17![American Airlines logo]()
$759
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:07 pm -
1 stop11h 38m
Thu 12/101:25 pm -
2 stops40h 34m
Deal found 10/19![United Airlines logo]()
$789
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:27 am -
1 stop14h 18m
Thu 12/1012:00 pm -
1 stop17h 26m
Deal found 10/19![American Airlines logo]()
$809
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:32 pm -
2 stops16h 58m
Thu 12/106:05 am -
2 stops21h 28m
Deal found 10/19![Delta logo]()
$813
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:35 pm -
1 stop30h 10m
Wed 1/61:25 pm -
2 stops31h 22m
Deal found 10/19![United Airlines logo]()
$1,090
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:30 am -
2 stops20h 15m
Thu 12/316:25 am -
2 stops20h 29m
Deal found 10/17![United Airlines logo]()
$1,143
This KAYAK deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:30 am -
2 stops24h 20m
Thu 12/3112:40 pm -
1 stop17h 13m
Deal found 10/17![British Airways logo]()
$1,169
This Justfly.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:30 am -
2 stops40h 30m
Wed 1/61:25 pm -
2 stops53h 55m
Deal found 10/19![Air Canada logo]()
$1,171
This Air Canada deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:20 am -
2 stops19h 40m
Tue 12/810:20 am -
3 stops19h 39m
Deal found 10/17![Multiple Airlines logo]()
$1,186
This WAYA deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:00 am -
1 stop17h 50m
Thu 12/314:15 pm -
1 stop28h 18m
Deal found 10/17![Multiple Airlines logo]()
$1,227
Best flights from Knoxville to MadridDiscover carefully curated flight deals from Knoxville to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
Discover carefully curated flight deals from Knoxville to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:10 am -
1 stop21h 20m
Thu 1/211:25 pm -
2 stops40h 34m
Deal found 10/19![United Airlines logo]()
$738
This Justfly.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:50 am -
2 stops25h 00m
Fri 2/126:40 am -
2 stops20h 09m
Deal found 10/20![British Airways logo]()
$812
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:32 pm -
2 stops16h 58m
Thu 12/106:05 am -
2 stops21h 28m
Deal found 10/19![Delta logo]()
$813
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:46 pm -
1 stop14h 44m
Wed 12/91:25 pm -
2 stops36h 22m
Deal found 10/18![United Airlines logo]()
$739
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:07 pm -
1 stop11h 38m
Thu 12/101:25 pm -
2 stops40h 34m
Deal found 10/19![United Airlines logo]()
$789
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/67:35 pm -
2 stops34h 10m
Sun 3/146:05 am -
2 stops22h 54m
Deal found 10/17![United Airlines logo]()
$821
Last-minute flights from Knoxville to MadridDiscover last-minute flight deals from Knoxville to Madrid. Data last updated October 21, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Madrid. Data last updated October 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop20h 05m
Mon 11/99:10 pm -
2 stops46h 48m
Deal found 10/20![Multiple Airlines logo]()
$1,655
This Booking.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:07 pm -
2 stops14h 43m
Mon 11/97:30 pm -
2 stops29h 16m
Deal found 10/20![British Airways logo]()
$2,146
One-way flights from Knoxville to MadridSearch for one-way flight options from Knoxville to Madrid. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
Search for one-way flight options from Knoxville to Madrid. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
This Expedia deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/77:57 am -
1 stop18h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![British Airways logo]()
$340
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/68:53 pm -
2 stops38h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![British Airways logo]()
$357
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/127:35 pm -
2 stops16h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/56:15 am -
3 stops43h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/511:48 am -
1 stop15h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$465
This Iberia deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/126:00 am -
1 stop25h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$478
This Cheapflightsfares deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:44 am -
2 stops20h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Aer Lingus logo]()
$491
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/66:15 am -
3 stops19h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$518
This British Airways deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:17 pm -
1 stop30h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![British Airways logo]()
$565
This Air Canada deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:45 am -
3 stops16h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Air Canada logo]()
$713
Find flight deals from Knoxville to Madrid
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 21, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $738 (United Airlines) |
One-way from | $340 (Expedia) |
Popular in | June |
Cheapest in | November |
Average price | $853 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 3/7
7:57 am-2:50 pm
2 stops24h 53m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$346
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 3/6
8:53 pm-8:55 am
1 stop30h 02m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$364
Quickest round-trip
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Fri 3/12
7:35 pm-5:50 pm
2 stops16h 15m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$407
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Fri 3/5
6:15 am-8:00 am
3 stops43h 45m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$426
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Fri 3/12
6:00 am-1:10 pm
1 stop25h 10m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$478
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 12/12
7:44 am-9:55 am
2 stops20h 11m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$491
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sat 3/6
6:15 am-8:00 am
3 stops19h 45m
Madrid Barajas
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$518
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Sun 1/17
6:10 am-9:30 am
1 stop21h 20m
Madrid Barajas
Thu 1/21
1:25 pm-11:59 pm
2 stops40h 34m
$738
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Wed 12/2
12:46 pm-9:30 am
1 stop14h 44m
Madrid Barajas
Wed 12/9
1:25 pm-7:47 pm
2 stops36h 22m
$739
KnoxvilleMadrid
TYS Knoxville McGhee Tyson - MAD Madrid Barajas
TYSMAD
Knoxville McGhee Tyson
Thu 12/3
2:07 pm-7:45 am
1 stop11h 38m
Madrid Barajas
Thu 12/10
1:25 pm-11:59 pm
2 stops40h 34m
$789
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Madrid
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Madrid
Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
TYS-MAD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Madrid
Reviews of airlines servicing Madrid
Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated October 21, 2026.
See what other customers who have flown with United Airlines and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Madrid?
Book flights to Madrid if you plan to visit one of these locationsGetafe
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Other flights to Madrid
Explore flights to Madrid departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Knoxville and Madrid flights
Browse other Knoxville and Madrid flight options. Last updated on October 21, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Madrid
Discover the top 2 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$549 | Average$1,095 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$591 | Average$794 | FlexibilityNo cancel fee | On-time69% |