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$423+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Knoxville to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$423
(Flighttix)

Popular in

June

Cheapest in

January

Average price

$728
Provider with most accurate pricing for Knoxville McGhee Tyson-Madrid Barajas flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Madrid Barajas flights.
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From Knoxville McGhee Tyson to Madrid Barajas
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Highest demand for flights based on searches. 26% potential increase in price ($349 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($48 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Flighttix deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/272:27 pmTYS - MAD
1 stop12h 38mVirgin Atlantic
Wed 11/1210:00 amMAD - TYS
2 stops16h 06mVirgin Atlantic
Deal found 10/16$423
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2711:35 amTYS - MAD
2 stops14h 25mDelta
Wed 11/1210:00 amMAD - TYS
2 stops16h 06mDelta
Deal found 10/16$443
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:45 amTYS - MAD
1 stop20h 20mUnited Airlines
Sun 12/71:45 pmMAD - TYS
2 stops26h 28mUnited Airlines
Deal found 10/16$512
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:45 amTYS - MAD
2 stops19h 15mUnited Airlines
Sat 12/61:35 pmMAD - TYS
2 stops26h 38mUnited Airlines
Deal found 10/15$537
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:35 amTYS - MAD
1 stop19h 20mAmerican Airlines
Fri 12/512:55 amMAD - TYS
1 stop16h 45mAmerican Airlines
Deal found 10/15$538
This Expedia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:08 pmTYS - MAD
2 stops17h 47mMultiple Airlines
Thu 1/811:00 pmMAD - TYS
2 stops27h 56mMultiple Airlines
Deal found 10/16$619

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Knoxville

Fly to

Madrid

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 10/27

2:27 pm-8:05 am

1 stop12h 38m

Madrid Barajas

Wed 11/12

10:00 am-8:06 pm

2 stops16h 06m

$423

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 10/27

11:35 am-7:00 am

2 stops14h 25m

Madrid Barajas

Wed 11/12

10:00 am-8:06 pm

2 stops16h 06m

$443

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 11/30

5:45 am-8:05 am

1 stop20h 20m

Madrid Barajas

Sun 12/7

1:45 pm-10:13 am

2 stops26h 28m

$512

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 11/29

9:50 am-8:05 am

1 stop16h 15m

Madrid Barajas

Sat 12/6

1:35 pm-10:13 am

2 stops26h 38m

$537

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 11/29

7:35 am-8:55 am

1 stop19h 20m

Madrid Barajas

Fri 12/5

12:55 am-11:40 am

1 stop16h 45m

$538

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 12/31

5:08 pm-4:55 pm

2 stops17h 47m

Madrid Barajas

Thu 1/8

11:00 pm-8:56 pm

2 stops27h 56m

$619

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Compare providers for flights from Knoxville to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MAD?

Find hourly flight availability from Knoxville to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 24% on flights from Knoxville to Madrid by exploring options for tickets in the afternoon.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated October 16, 2025.
See what other customers who have flown with United Airlines, American Airlines, and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,982 reviews

Overall

7.4

Comfort

7.3

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
United Airlines
7.4
Good
8,982 reviews
United Airlines
7.4
Good
8,982 reviews

Overall

7.4

Comfort

7.3

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
American Airlines
7.2
Good
11,040 reviews
United Airlines
7.4
Good
8,982 reviews

Overall

7.4

Comfort

7.3

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
British Airways
6.7
Okay
7,457 reviews
United Airlines
7.4
Good
8,982 reviews

Overall

7.4

Comfort

7.3

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Madrid?

    Departing from Knoxville to Madrid will take you 12h 38m. There are 4222 mi between Knoxville and Madrid. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Madrid round-trip?

    According to our current data, United Airlines ($562), British Airways ($594), and American Airlines ($642) offers the cheapest pricing from Knoxville to Madrid. United Airlines is currently priced 41% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

    Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

  • Can I find deals for business class flights from Knoxville to Madrid?

    Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Madrid?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

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Alternative routes for Knoxville to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Madrid flights
Memphis to Madrid flights

Top 3 airlines flying from Knoxville to Madrid

Discover the top 3 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$562Average$875FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$594Average$800FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$642Average$1,106FlexibilityNo cancel feeOn-time71%

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