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$553+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Cheap flight deals from Knoxville to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$688
(Finnair)

One-way from

$553
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$787
Provider with most accurate pricing for Knoxville McGhee Tyson-Madrid Barajas flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Madrid Barajas flights.
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From Knoxville McGhee Tyson to Madrid Barajas
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One-way flight from Knoxville McGhee Tyson to Madrid Barajas
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Highest demand for flights based on searches. 26% potential increase in price ($354 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($48 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Finnair deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:20 amTYS - MAD
1 stop13h 25mMultiple Airlines
Tue 12/231:15 pmMAD - TYS
1 stop13h 28mMultiple Airlines
Deal found 11/17$688
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:35 amTYS - MAD
1 stop18h 40mDelta
Thu 1/86:00 amMAD - TYS
2 stops20h 47mDelta
Deal found 11/16$813
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:59 pmTYS - MAD
1 stop32h 16mDelta
Thu 1/86:00 amMAD - TYS
2 stops20h 47mDelta
Deal found 11/16$818
This British Airways deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:58 pmTYS - MAD
2 stops17h 52mBritish Airways
Thu 1/85:20 pmMAD - TYS
2 stops34h 49mBritish Airways
Deal found 11/16$858
This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:05 amTYS - MAD
2 stops20h 10mUnited Airlines
Tue 12/236:00 amMAD - TYS
2 stops23h 59mUnited Airlines
Deal found 11/17$892
This Ovago deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:29 pmTYS - MAD
2 stops18h 06mBritish Airways
Tue 12/231:15 pmMAD - TYS
1 stop13h 28mBritish Airways
Deal found 11/17$896
This British Airways deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:46 pmTYS - MAD
2 stops15h 54mBritish Airways
Fri 1/96:45 amMAD - TYS
2 stops18h 01mBritish Airways
Deal found 11/16$949
This British Airways deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:15 pmTYS - MAD
1 stop31h 30mBritish Airways
Fri 1/96:45 amMAD - TYS
2 stops20h 36mBritish Airways
Deal found 11/16$958

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Knoxville

Fly to

Madrid

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 12/12

10:20 am-5:45 am

1 stop13h 25m

Madrid Barajas

Tue 12/23

1:15 pm-8:43 pm

1 stop13h 28m

$688

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 3/6

6:55 pm-4:40 pm

2 stops39h 45m

Madrid Barajas

Sun 3/15

5:55 am-2:50 pm

2 stops37h 55m

$706

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 3/6

7:00 am-4:10 pm

2 stops27h 10m

Madrid Barajas

Sat 3/14

6:00 am-10:49 am

2 stops33h 49m

$706

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 3/6

11:16 am-8:40 am

1 stop15h 24m

Madrid Barajas

Sun 3/15

1:00 pm-11:41 pm

1 stop15h 41m

$787

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 3/6

11:16 am-8:40 am

1 stop15h 24m

Madrid Barajas

Sat 3/14

1:00 pm-9:29 pm

1 stop13h 29m

$827

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 12/31

2:58 pm-2:50 pm

2 stops17h 52m

Madrid Barajas

Thu 1/8

5:20 pm-10:09 pm

2 stops34h 49m

$858

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 12/12

7:05 am-9:15 am

2 stops20h 10m

Madrid Barajas

Tue 12/23

6:00 am-11:59 pm

2 stops23h 59m

$892

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 4/15

5:17 am-9:55 am

2 stops22h 38m

$553

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 4/15

2:24 pm-8:05 am

1 stop11h 41m

$605

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 4/15

7:00 am-8:05 am

3 stops19h 05m

$618

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Compare providers for flights from Knoxville to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MAD?

Find hourly flight availability from Knoxville to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 24% on flights from Knoxville to Madrid by exploring options for tickets in the afternoon.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated November 17, 2025.
See what other customers who have flown with United Airlines, American Airlines, and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,014 reviews

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,014 reviews
United Airlines
7.4
Good
9,014 reviews

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,047 reviews
United Airlines
7.4
Good
9,014 reviews

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
British Airways
6.7
Okay
7,528 reviews
United Airlines
7.4
Good
9,014 reviews

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Madrid?

    Departing from Knoxville to Madrid will take you 39h 45m. There are 4222 mi between Knoxville and Madrid.

  • What are the cheapest airlines flying from Knoxville to Madrid round-trip?

    According to our current data, United Airlines ($571), British Airways ($594), and American Airlines ($642) offers the cheapest pricing from Knoxville to Madrid. United Airlines is currently priced 40% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Knoxville to Madrid one-way?

    The cheapest airline one-way is Aer Lingus, with whom users have recently found tickets for as low as $553. However, be on the lookout for offers from Lufthansa and United Airlines, as they are both options that can get you from Knoxville to Madrid for a low price.

  • Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

    Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

  • Can I find deals for business class flights from Knoxville to Madrid?

    Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Madrid?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

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Alternative routes for Knoxville to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Madrid

Discover the top 3 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$571Average$875FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$594Average$800FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$642Average$1,106FlexibilityNo cancel feeOn-time71%

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