HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Madrid

$352+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Feb 13 — Feb 201
Fri 2/13
Fri 2/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Madrid with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 14, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$414
(oojo)

One-way from

$368
(oojo)

Popular in

February

Cheapest in

September
Provider with most accurate pricing for Knoxville McGhee Tyson-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Madrid Barajas flights.
Search Deals
From Knoxville McGhee Tyson to Madrid Barajas
Search Deals
One-way flight from Knoxville McGhee Tyson to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($291 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($82 potential savings vs. average RT price).
Search Deals

Find flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 14, 2026.

This oojo deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/254:02 pm
TYS
-
MAD
2 stops15h 33m
British Airways
Wed 3/41:15 pm
MAD
-
TYS
1 stop13h 33m
British Airways
Deal found 1/13$414
This Flighttix deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/256:41 pm
TYS
-
MAD
1 stop32h 34m
Virgin Atlantic
Tue 2/1010:00 am
MAD
-
TYS
2 stops19h 45m
Virgin Atlantic
Deal found 1/12$421
This oojo deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:10 am
TYS
-
MAD
1 stop20h 45m
British Airways
Fri 3/61:00 pm
MAD
-
TYS
1 stop14h 55m
British Airways
Deal found 1/13$424
This Cheapflightsfares deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/115:15 pm
TYS
-
MAD
2 stops19h 55m
British Airways
Wed 2/181:15 pm
MAD
-
TYS
1 stop13h 33m
British Airways
Deal found 1/12$441
This oojo deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:10 am
TYS
-
MAD
2 stops23h 45m
British Airways
Sat 2/281:15 pm
MAD
-
TYS
1 stop13h 52m
British Airways
Deal found 1/12$451
This oojo deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:10 am
TYS
-
MAD
1 stop20h 45m
British Airways
Sat 3/712:50 pm
MAD
-
TYS
2 stops37h 15m
British Airways
Deal found 1/13$455

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Knoxville

Fly to

Madrid

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 2/25

4:02 pm-1:35 pm

2 stops15h 33m

Madrid Barajas

Wed 3/4

1:15 pm-8:48 pm

1 stop13h 33m

$414

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 1/25

9:40 am-8:00 am

2 stops16h 20m

Madrid Barajas

Tue 2/10

10:00 am-11:45 pm

2 stops19h 45m

$444

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 2/25

4:04 pm-6:30 pm

2 stops20h 26m

Madrid Barajas

Fri 3/6

2:35 pm-6:13 pm

2 stops33h 38m

$444

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 2/18

4:02 pm-8:05 pm

2 stops22h 03m

Madrid Barajas

Sat 2/28

1:15 pm-9:07 pm

1 stop13h 52m

$451

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 2/11

5:17 pm-7:10 pm

2 stops19h 53m

Madrid Barajas

Wed 2/18

6:45 am-8:48 pm

2 stops20h 03m

$452

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 2/18

5:00 pm-9:15 am

1 stop10h 15m

Madrid Barajas

Sat 2/28

11:15 am-11:52 pm

1 stop18h 37m

$464

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 2/15

5:40 am-6:15 am

1 stop18h 35m

Madrid Barajas

Sat 2/21

12:55 am-11:31 am

1 stop16h 36m

$464

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 2/27

12:21 pm-9:25 am

1 stop15h 04m

Madrid Barajas

Fri 3/6

12:40 pm-11:55 pm

1 stop17h 15m

$464

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 2/25

12:21 pm-9:25 am

1 stop15h 04m

Madrid Barajas

Fri 3/6

12:55 am-5:31 pm

1 stop22h 36m

$464

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 5/20

7:20 pm-6:50 am

2 stops29h 30m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Showing 1-10 of 18 results
1
2

Compare providers for flights from Knoxville to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated January 14, 2026.
See what other customers who have flown with American Airlines and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,116 reviews

Boarding

7.5

Food

6.4

Entertainment

6.9

Overall

7.2

Crew

8.0

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.
American Airlines
7.2
Good
11,116 reviews
American Airlines
7.2
Good
11,116 reviews

Boarding

7.5

Food

6.4

Entertainment

6.9

Overall

7.2

Crew

8.0

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.
British Airways
6.7
Okay
7,666 reviews
American Airlines
7.2
Good
11,116 reviews

Boarding

7.5

Food

6.4

Entertainment

6.9

Overall

7.2

Crew

8.0

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Madrid?

    Departing from Knoxville to Madrid will take you 15h 33m. There are 4222 mi between Knoxville and Madrid. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Madrid round-trip?

    According to our current data, American Airlines ($586), and British Airways ($612) offers the cheapest pricing from Knoxville to Madrid. American Airlines is currently priced 44% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

    Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

  • Can I find deals for business class flights from Knoxville to Madrid?

    Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Madrid?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Madrid flights
Memphis to Madrid flights

Top 2 airlines flying from Knoxville to Madrid

Discover the top 2 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$586Average$1,140FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$612Average$712FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.