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$279+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Gurufare deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:18 pmTYS - MAD
1 stop15h 07mFinnair
Fri 1/97:40 amMAD - TYS
2 stops21h 07mFinnair
Deal found 12/2$651
This Expedia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:40 amTYS - MAD
2 stops16h 20mAir Canada
Fri 12/121:35 pmMAD - TYS
2 stops33h 36mAir Canada
Deal found 12/2$672
This Booking.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:40 amTYS - MAD
2 stops16h 20mMultiple Airlines
Fri 12/1211:05 amMAD - TYS
1 stop14h 24mMultiple Airlines
Deal found 12/2$682
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amTYS - MAD
2 stops20h 15mUnited Airlines
Sun 1/111:45 pmMAD - TYS
2 stops35h 42mUnited Airlines
Deal found 12/2$696
This Finnair deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:24 pmTYS - MAD
1 stop10h 21mMultiple Airlines
Fri 1/97:40 amMAD - TYS
2 stops21h 07mMultiple Airlines
Deal found 12/3$734
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/283:01 pmTYS - MAD
1 stop11h 49mAmerican Airlines
Mon 1/1212:00 pmMAD - TYS
1 stop16h 09mAmerican Airlines
Deal found 12/2$735
This Expedia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:58 pmTYS - MAD
2 stops14h 57mBritish Airways
Fri 1/96:45 amMAD - TYS
2 stops16h 04mBritish Airways
Deal found 12/2$752
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:59 pmTYS - MAD
1 stop32h 16mDelta
Fri 1/910:00 amMAD - TYS
2 stops30h 15mDelta
Deal found 12/2$784
This KAYAK deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:35 pmTYS - MAD
2 stops40h 25mLufthansa
Sun 1/111:45 pmMAD - TYS
2 stops35h 42mLufthansa
Deal found 12/2$817

Find flight deals from Knoxville to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$425
(oojo)

One-way from

$279
(oojo)

Popular in

June

Cheapest in

January

Average price

$673
Provider with most accurate pricing for Knoxville McGhee Tyson-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Madrid Barajas flights.
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From Knoxville McGhee Tyson to Madrid Barajas
Search Deals
One-way flight from Knoxville McGhee Tyson to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($354 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Knoxville

Fly to

Madrid

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 1/14

2:19 pm-11:55 am

2 stops15h 36m

Madrid Barajas

Thu 2/26

1:00 pm-11:54 pm

1 stop16h 54m

$425

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 1/14

7:41 am-5:45 am

1 stop16h 04m

Madrid Barajas

Wed 2/25

12:55 am-11:27 am

1 stop16h 32m

$438

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 1/23

4:06 pm-9:15 am

1 stop11h 09m

Madrid Barajas

Tue 1/27

11:15 am-11:45 pm

1 stop18h 30m

$463

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 2/15

7:40 am-8:50 am

1 stop19h 10m

Madrid Barajas

Sun 2/22

12:00 pm-9:23 pm

1 stop15h 23m

$463

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 1/15

2:25 pm-11:10 am

2 stops14h 45m

Madrid Barajas

Mon 1/19

1:35 pm-2:49 pm

2 stops31h 14m

$467

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 1/15

11:19 am-5:45 am

2 stops12h 26m

Madrid Barajas

Tue 3/17

12:00 pm-9:32 pm

1 stop14h 32m

$468

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 1/23

4:06 pm-9:15 am

1 stop11h 09m

Madrid Barajas

Tue 1/27

10:00 am-7:59 pm

2 stops15h 59m

$468

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 1/23

11:07 am-9:15 am

2 stops16h 08m

Madrid Barajas

Tue 1/27

1:35 pm-7:27 pm

2 stops35h 52m

$473

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 1/23

2:25 pm-11:10 am

2 stops14h 45m

Madrid Barajas

Sat 1/31

6:00 am-7:27 pm

2 stops19h 27m

$475

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 1/20

5:15 pm-4:55 pm

2 stops17h 40m

Madrid Barajas

Fri 1/30

12:40 pm-6:46 pm

1 stop12h 06m

$475

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 19 results
1
2

Compare providers for flights from Knoxville to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MAD?

Find hourly flight availability from Knoxville to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 24% on flights from Knoxville to Madrid by exploring options for tickets in the afternoon.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated December 4, 2025.
See what other customers who have flown with American Airlines and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,043 reviews

Food

6.5

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.
American Airlines
7.2
Good
11,043 reviews
American Airlines
7.2
Good
11,043 reviews

Food

6.5

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.
British Airways
6.7
Okay
7,559 reviews
American Airlines
7.2
Good
11,043 reviews

Food

6.5

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Madrid?

    Departing from Knoxville to Madrid will take you 11h 09m. There are 4222 mi between Knoxville and Madrid. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Madrid round-trip?

    According to our current data, British Airways ($636), and American Airlines ($642) offers the cheapest pricing from Knoxville to Madrid. British Airways is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

    Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

  • Can I find deals for business class flights from Knoxville to Madrid?

    Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Madrid?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

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Alternative routes for Knoxville to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Madrid flights
Memphis to Madrid flights

Top 2 airlines flying from Knoxville to Madrid

Discover the top 2 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$636Average$800FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$642Average$1,111FlexibilityNo cancel feeOn-time71%

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