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$433+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Mar 25 — Apr 11
Wed 3/25
Wed 4/1
1 adult, Economy
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Cheap flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.

This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:10 pm
TYS
-
MAD
1 stop33h 10m
Iberia
Mon 4/271:35 pm
MAD
-
TYS
1 stop13h 46m
Iberia
Deal found 2/19$541
This oojo deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:57 pm
TYS
-
MAD
1 stop29h 33m
British Airways
Mon 4/275:30 pm
MAD
-
TYS
2 stops32h 48m
British Airways
Deal found 2/19$547
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:20 pm
TYS
-
MAD
2 stops29h 30m
Air Canada
Mon 4/2712:45 pm
MAD
-
TYS
2 stops28h 05m
Air Canada
Deal found 2/19$554
This Air Canada deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:20 pm
TYS
-
MAD
2 stops29h 30m
Multiple Airlines
Mon 4/2712:45 pm
MAD
-
TYS
3 stops28h 05m
Multiple Airlines
Deal found 2/19$567
This oojo deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:06 pm
TYS
-
MAD
1 stop14h 24m
British Airways
Wed 4/2210:25 am
MAD
-
TYS
1 stop17h 59m
British Airways
Deal found 2/22$585
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:49 am
TYS
-
MAD
2 stops15h 16m
United Airlines
Wed 4/2212:45 pm
MAD
-
TYS
2 stops16h 18m
United Airlines
Deal found 2/22$594
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:30 am
TYS
-
MAD
2 stops26h 15m
United Airlines
Fri 10/911:15 am
MAD
-
TYS
1 stop28h 45m
United Airlines
Deal found 2/22$598
This Finnair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:23 am
TYS
-
MAD
1 stop18h 27m
Multiple Airlines
Wed 9/2312:20 pm
MAD
-
TYS
1 stop15h 14m
Multiple Airlines
Deal found 2/23$620
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:50 am
TYS
-
MAD
1 stop20h 15m
United Airlines
Wed 9/235:55 am
MAD
-
TYS
2 stops20h 27m
United Airlines
Deal found 2/23$621

Find flight deals from Knoxville to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$585
(oojo)

One-way from

$433
(oojo)

Popular in

June

Cheapest in

September
Provider with most accurate pricing for Knoxville McGhee Tyson-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Madrid Barajas flights.
Search Deals
From Knoxville McGhee Tyson to Madrid Barajas
Search Deals
One-way flight from Knoxville McGhee Tyson to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($294 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($52 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Knoxville

Fly to

Madrid

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 4/18

5:10 pm-8:20 am

1 stop33h 10m

Madrid Barajas

Mon 4/27

1:35 pm-9:21 pm

1 stop13h 46m

$541

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 4/18

5:57 pm-5:30 am

1 stop29h 33m

Madrid Barajas

Mon 4/27

5:30 pm-8:18 pm

2 stops32h 48m

$547

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 4/18

7:20 pm-6:50 am

2 stops29h 30m

Madrid Barajas

Mon 4/27

12:45 pm-10:50 am

2 stops28h 05m

$554

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 4/18

7:20 pm-6:50 am

2 stops29h 30m

Madrid Barajas

Mon 4/27

12:45 pm-10:50 am

3 stops28h 05m

$567

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 5/13

7:00 am-6:50 am

2 stops17h 50m

Madrid Barajas

Tue 5/19

12:45 pm-5:08 pm

2 stops34h 23m

$750

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 5/13

11:31 am-8:20 am

1 stop14h 49m

Madrid Barajas

Tue 5/19

11:45 am-9:21 pm

1 stop15h 36m

$766

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 5/23

5:57 pm-6:50 am

2 stops30h 53m

Madrid Barajas

Tue 6/2

12:45 pm-12:30 am

2 stops41h 45m

$804

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 5/11

7:18 pm-4:45 pm

2 stops39h 27m

Madrid Barajas

Sun 5/24

1:30 pm-12:30 am

2 stops41h 00m

$826

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 5/11

5:57 pm-12:15 pm

1 stop12h 18m

Madrid Barajas

Sun 5/24

12:20 pm-9:25 pm

2 stops15h 05m

$836

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

6:10 am-8:55 am

1 stop20h 45m

$542

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 11 results
1
2

Compare providers for flights from Knoxville to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,067). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated February 23, 2026.
See what other customers who have flown with American Airlines and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,344 reviews

Crew

8.0

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,344 reviews
American Airlines
7.2
Good
11,344 reviews

Crew

8.0

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
British Airways
6.7
Okay
7,762 reviews
American Airlines
7.2
Good
11,344 reviews

Crew

8.0

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Madrid?

    Departing from Knoxville to Madrid will take you 29h 30m. There are 4222 mi between Knoxville and Madrid. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Madrid round-trip?

    According to our current data, American Airlines ($586), and British Airways ($612) offers the cheapest pricing from Knoxville to Madrid. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

    Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

  • Can I find deals for business class flights from Knoxville to Madrid?

    Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Madrid?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,067). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

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Alternative routes for Knoxville to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Madrid flights
Memphis to Madrid flights

Top 2 airlines flying from Knoxville to Madrid

Discover the top 2 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$586Average$1,021FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$612Average$717FlexibilityNo cancel feeOn-time70%

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