What’s the cheapest layover airport for flights from Knoxville to Madrid?

Philadelphia (PHL) is the most affordable 1-stop option, with an average round-trip price of $817.

What’s the top layover airport for flights from Knoxville to Madrid?

Philadelphia (PHL) – chosen by Cheapflights users on 50% of 1-stop itineraries from Knoxville to Madrid on Cheapflights.

Which airport typically offers the quickest layover for flights from Knoxville to Madrid?

Flights via Philadelphia (PHL) offer the fastest connection on this route, with an average layover time of 2h 00m.

What’s the fastest layover option from Knoxville to Madrid?

Flights via Philadelphia (PHL) have the shortest average one-way travel time for 1-stop routes: 10h 23m.

How long is the flight from Knoxville to Madrid?

Departing from Knoxville to Madrid will take you 23h 45m. There are 4222 mi between Knoxville and Madrid. This flight may include one or multiple stops.

What are the cheapest airlines flying from Knoxville to Madrid round-trip?

According to our current data, American Airlines ($586), and British Airways ($612) offers the cheapest pricing from Knoxville to Madrid. American Airlines is currently priced 43% below the average price you’ll pay for this route.

In terms of precipitation, rainfall in Madrid ranges from 0.4 - 2.4 inches per month. November is typically the wettest month, when rainfall can reach 2.4 in. July is typically the driest time to visit Madrid when rainfall is around 0.4 in.

If weather is an important factor for your trip to Madrid, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from TYS to MAD?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Madrid as you normally would.

Most accurate provider : When it comes to deals on Knoxville-Madrid flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Madrid?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

Can I find deals for business class flights from Knoxville to Madrid?

Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$402+ Flights from Knoxville to Madrid, Spain

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Cheap flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Tue 12/301:24 pmTYS - MAD

1 stop10h 21mMultiple Airlines

Thu 1/110:00 amMAD - TYS

1 stop14h 31mMultiple Airlines

Deal found 12/26

$1,356

Tue 12/3012:00 pmTYS - MAD

2 stops16h 15mKLM

Thu 1/17:05 amMAD - TYS

2 stops18h 22mKLM

Deal found 12/26

$1,472

Tue 12/309:50 amTYS - MAD

3 stops16h 10mAir Canada

Thu 1/17:40 amMAD - TYS

3 stops22h 19mAir Canada

Deal found 12/26

$3,435

Best flights from Knoxville to Madrid
Discover carefully curated flight deals from Knoxville to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 27, 2025.

Mon 2/97:44 amTYS - MAD

2 stops27h 11mBritish Airways

Mon 2/168:50 pmMAD - TYS

2 stops31h 12mBritish Airways

Deal found 12/25

$482

Sun 2/1512:20 pmTYS - MAD

1 stop15h 05mMultiple Airlines

Sun 2/221:00 pmMAD - TYS

1 stop15h 00mMultiple Airlines

Deal found 12/25

$489

Thu 3/510:55 amTYS - MAD

2 stops23h 45mUnited Airlines

Fri 3/138:35 amMAD - TYS

2 stops31h 14mUnited Airlines

Deal found 12/25

$498

Thu 3/55:35 amTYS - MAD

2 stops20h 25mDelta

Fri 3/1310:05 amMAD - TYS

1 stop12h 48mDelta

Deal found 12/25

$593

Mon 2/97:44 amTYS - MAD

1 stop19h 11mMultiple Airlines

Mon 2/1610:00 amMAD - TYS

1 stop14h 32mMultiple Airlines

Deal found 12/25

$489

Sat 3/76:40 amTYS - MAD

2 stops23h 15mBritish Airways

Sun 3/152:35 pmMAD - TYS

2 stops35h 30mBritish Airways

Deal found 12/25

$582

Thu 3/57:00 amTYS - MAD

1 stop16h 45mMultiple Airlines

Fri 3/131:00 pmMAD - TYS

1 stop13h 55mMultiple Airlines

Deal found 12/25

$539

Mon 4/67:00 amTYS - MAD

2 stops19h 05mUnited Airlines

Mon 4/138:25 amMAD - TYS

2 stops41h 31mUnited Airlines

Deal found 12/26

$653

Mon 4/67:39 pmTYS - MAD

1 stop12h 41mMultiple Airlines

Mon 4/131:00 pmMAD - TYS

1 stop16h 43mMultiple Airlines

Deal found 12/26

$668

Last-minute flights from Knoxville to Madrid
Discover last-minute flight deals from Knoxville to Madrid. Data last updated December 27, 2025 and is based on user searches.

Tue 12/301:24 pmTYS - MAD

1 stop10h 21mMultiple Airlines

Thu 1/110:00 amMAD - TYS

1 stop14h 31mMultiple Airlines

Deal found 12/26

$1,356

Tue 12/3012:00 pmTYS - MAD

2 stops16h 15mKLM

Thu 1/17:05 amMAD - TYS

2 stops18h 22mKLM

Deal found 12/26

$1,472

Tue 12/309:50 amTYS - MAD

3 stops16h 10mAir Canada

Thu 1/17:40 amMAD - TYS

3 stops22h 19mAir Canada

Deal found 12/26

$3,435

Fri 1/166:45 amTYS - MAD

2 stops20h 30mUnited Airlines

Tue 1/201:35 pmMAD - TYS

2 stops35h 52mUnited Airlines

Deal found 12/25

$674

Fri 1/165:15 pmTYS - MAD

2 stops22h 55mBritish Airways

Tue 1/2012:40 pmMAD - TYS

1 stop16h 14mBritish Airways

Deal found 12/24

$885

Thu 1/229:30 amTYS - MAD

2 stops16h 30mAir Canada

Mon 1/261:35 pmMAD - TYS

2 stops35h 52mAir Canada

Deal found 12/26

$673

One-way flights from Knoxville to Madrid
Search for one-way flight options from Knoxville to Madrid. Find affordable one-way fares based on user searches. Data last updated December 27, 2025.

Thu 3/511:16 amTYS - MAD

2 stops40h 39mAer Lingus

Deal found 12/26

$402

Thu 3/512:00 pmTYS - MAD

1 stop15h 15mKLM

Deal found 12/25

$493

Thu 3/57:00 amTYS - MAD

3 stops19h 00mMultiple Airlines

Deal found 12/25

$496

Find flight deals from Knoxville to Madrid

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$476 (oojo)
One-way from	$402 (Ovago)
Popular in	June
Cheapest in	December
Average price	$673

Provider with most accurate pricing for Knoxville McGhee Tyson-Madrid Barajas flight deals.

Search Deals

Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Madrid Barajas flights.

Search Deals

From Knoxville McGhee Tyson to Madrid Barajas

Search Deals

One-way flight from Knoxville McGhee Tyson to Madrid Barajas

Search Deals

Highest demand for flights based on searches. 21% potential increase in price ($285 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($42 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 2/9

7:44 am-4:55 pm

2 stops27h 11m

Madrid Barajas

Mon 2/16

8:50 pm-10:02 pm

2 stops31h 12m

$482

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 2/15

12:20 pm-9:25 am

1 stop15h 05m

Madrid Barajas

Sun 2/22

1:00 pm-10:00 pm

1 stop15h 00m

$489

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 2/9

7:44 am-8:55 am

1 stop19h 11m

Madrid Barajas

Mon 2/16

10:00 am-6:32 pm

1 stop14h 32m

$489

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

10:55 am-4:40 pm

2 stops23h 45m

Madrid Barajas

Fri 3/13

8:35 am-10:49 am

2 stops31h 14m

$498

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

7:00 am-5:45 am

1 stop16h 45m

Madrid Barajas

Fri 3/13

1:00 pm-9:55 pm

1 stop13h 55m

$539

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 3/7

6:40 am-11:55 am

2 stops23h 15m

Madrid Barajas

Sun 3/15

2:35 pm-9:05 pm

2 stops35h 30m

$582

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

5:35 am-8:00 am

2 stops20h 25m

Madrid Barajas

Fri 3/13

10:05 am-5:53 pm

1 stop12h 48m

$593

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 4/6

7:00 am-8:05 am

2 stops19h 05m

Madrid Barajas

Mon 4/13

8:25 am-7:56 pm

2 stops41h 31m

$653

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 4/6

7:39 pm-2:20 pm

1 stop12h 41m

Madrid Barajas

Mon 4/13

1:00 pm-11:43 pm

1 stop16h 43m

$668

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

11:16 am-9:55 am

2 stops40h 39m

$402

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 12 results

Compare providers for flights from Knoxville to Madrid

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
AranGrant	Price Accuracy2 stars	Trust Score*3 stars
Ovago	Price Accuracy2 stars	Trust Score*2 stars
Trip.com	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Knoxville-Madrid flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Madrid flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Madrid flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Knoxville-Madrid flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

Prices

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Madrid

See what other customers who have flown with American Airlines and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,066 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

American Airlines

7.2

Good

11,066 reviews

American Airlines

7.2

Good

11,066 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

British Airways

6.7

Okay

7,614 reviews

American Airlines

7.2

Good

11,066 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

How long is the flight from Knoxville to Madrid?
Departing from Knoxville to Madrid will take you 23h 45m. There are 4222 mi between Knoxville and Madrid. This flight may include one or multiple stops.
What are the cheapest airlines flying from Knoxville to Madrid round-trip?
According to our current data, American Airlines ($586), and British Airways ($612) offers the cheapest pricing from Knoxville to Madrid. American Airlines is currently priced 43% below the average price you’ll pay for this route.
Can I find deals for flights from Knoxville to Madrid that include hotel bookings?
Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Madrid?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.
Can I find deals for business class flights from Knoxville to Madrid?
Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Madrid?
Currently, October is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $181). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Madrid

Nashville to Madrid flights

Memphis to Madrid flights

Other flights to Madrid

Top 2 airlines flying from Knoxville to Madrid

Airline	Cheapest	Average	Flexibility	On-time
British Airways	Cheapest$612	Average$722	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$642	Average$1,141	FlexibilityNo cancel fee	On-time71%

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$402+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Madrid with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to MadridExplore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Find flight deals from Knoxville to Madrid

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Compare providers for flights from Knoxville to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Madrid in December.

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

What’s the top layover airport for flights from Knoxville to Madrid?

What’s the cheapest layover airport for flights from Knoxville to Madrid?

What’s the fastest layover option from Knoxville to Madrid?

Which airport typically offers the quickest layover for flights from Knoxville to Madrid?

Reviews of airlines servicing Madrid

See what other customers who have flown with American Airlines and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Knoxville to Madrid?

What are the cheapest airlines flying from Knoxville to Madrid round-trip?

Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

How can I find direct flights from Knoxville to Madrid?

Can I find deals for business class flights from Knoxville to Madrid?

What is the cheapest month to book a flight from Knoxville to Madrid?

Traveling to a place near Madrid?

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Alternative routes for Knoxville to Madrid

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Top 2 airlines flying from Knoxville to Madrid

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Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.