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$240+ Cheap flights from Knoxville (TYS) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAD
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
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Cheap flight deals from Knoxville to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 16, 2025.

Round-trip from

$438
(Delta)

One-way from

$240
(Mytrip)

Popular in

June

Cheapest in

January

Average price

$896
From Knoxville McGhee Tyson to Madrid Barajas
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One-way flight from Knoxville McGhee Tyson to Madrid Barajas
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Highest demand for flights based on searches. 24% potential increase in price ($321 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($45 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Knoxville to Madrid

Cheapest flights from Knoxville to Madrid
Explore the most affordable flight options available from Knoxville to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:44 amTYS - MAD
1 stop21h 46mDelta
Thu 11/1311:00 amMAD - TYS
1 stop13h 13mDelta
Deal found 8/13$438
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:44 amTYS - MAD
1 stop21h 46mDelta
Fri 11/1410:00 amMAD - TYS
2 stops17h 32mDelta
Deal found 8/13$442
This KLM deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1012:00 pmTYS - MAD
2 stops14h 00mKLM
Wed 11/1911:00 amMAD - TYS
1 stop13h 13mKLM
Deal found 8/15$443
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:44 amTYS - MAD
1 stop21h 46mDelta
Wed 11/196:00 amMAD - TYS
2 stops23h 27mDelta
Deal found 8/13$462
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:44 amTYS - MAD
1 stop21h 46mDelta
Tue 11/1811:00 amMAD - TYS
2 stops16h 32mDelta
Deal found 8/13$463
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:30 amTYS - MAD
2 stops18h 30mDelta
Wed 11/196:00 amMAD - TYS
2 stops22h 59mDelta
Deal found 8/13$466
This Finnair deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/512:01 pmTYS - MAD
1 stop11h 44mMultiple Airlines
Thu 11/131:00 pmMAD - TYS
1 stop12h 33mMultiple Airlines
Deal found 8/13$488
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:20 pmTYS - MAD
1 stop30h 45mUnited Airlines
Sun 11/161:35 pmMAD - TYS
2 stops36h 58mUnited Airlines
Deal found 8/13$490
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/63:59 pmTYS - MAD
1 stop11h 31mDelta
Fri 11/1410:00 amMAD - TYS
2 stops17h 32mDelta
Deal found 8/13$492
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/912:00 pmTYS - MAD
2 stops16h 15mDelta
Wed 11/196:00 amMAD - TYS
2 stops20h 39mDelta
Deal found 8/14$493
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:20 pmTYS - MAD
1 stop30h 45mUnited Airlines
Thu 11/136:00 amMAD - TYS
2 stops23h 59mUnited Airlines
Deal found 8/13$494

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Knoxville

Fly to

Madrid

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

5:44 am-9:30 am

1 stop21h 46m

Madrid Barajas

Thu 11/13

11:00 am-6:13 pm

1 stop13h 13m

$438

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

5:44 am-9:30 am

1 stop21h 46m

Madrid Barajas

Fri 11/14

10:00 am-9:32 pm

2 stops17h 32m

$442

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 11/10

12:00 pm-8:00 am

2 stops14h 00m

Madrid Barajas

Wed 11/19

11:00 am-6:13 pm

1 stop13h 13m

$443

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

5:44 am-9:30 am

1 stop21h 46m

Madrid Barajas

Wed 11/19

6:00 am-11:27 pm

2 stops23h 27m

$462

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 11/5

5:44 am-9:30 am

1 stop21h 46m

Madrid Barajas

Tue 11/18

11:00 am-9:32 pm

2 stops16h 32m

$463

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 11/10

7:30 am-8:00 am

2 stops18h 30m

Madrid Barajas

Wed 11/19

6:00 am-10:59 pm

2 stops22h 59m

$466

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 11/11

12:00 pm-8:00 am

2 stops14h 00m

Madrid Barajas

Wed 11/19

6:00 am-5:17 pm

2 stops17h 17m

$466

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 11/10

7:30 am-8:00 am

2 stops18h 30m

Madrid Barajas

Tue 11/18

11:00 am-9:32 pm

2 stops16h 32m

$468

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 11/11

10:05 am-8:00 am

2 stops15h 55m

Madrid Barajas

Tue 11/18

11:00 am-9:32 pm

2 stops16h 32m

$468

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 11/11

6:05 am-5:45 am

1 stop17h 40m

Madrid Barajas

Wed 11/19

1:15 pm-9:04 pm

1 stop13h 49m

$488

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Showing 1-10 of 13 results
1
2

Best time to book a flight from Knoxville to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Madrid

What is the cheapest month to book a flight from Knoxville to Madrid?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $543). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,053). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MAD?

Find hourly flight availability from Knoxville to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 25% on flights from Knoxville to Madrid by exploring options for tickets in the afternoon.

What’s the top layover airport for flights from Knoxville to Madrid?

Share of 1-stop round-trip flights from Knoxville to Madrid chosen by Cheapflights users in the past 12 months, using the same layover each way.

Philadelphia (PHL) – chosen by Cheapflights users on 86% of 1-stop itineraries from Knoxville to Madrid on Cheapflights.

What’s the cheapest layover airport for flights from Knoxville to Madrid?

Average round-trip fare for 1-stop flights from Knoxville to Madrid, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Philadelphia (PHL) is the most affordable 1-stop option, with an average round-trip price of $677.

What’s the fastest layover option from Knoxville to Madrid?

Shortest average travel time for 1-stop one-way flights from Knoxville to Madrid, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Philadelphia (PHL) have the shortest average one-way travel time for 1-stop routes: 9h 45m.

Which airport typically offers the quickest layover for flights from Knoxville to Madrid?

Average layover duration for 1-stop one-way flights from Knoxville to Madrid, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Philadelphia (PHL) offer the fastest connection on this route, with an average layover time of 1h 53m.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated August 16, 2025.
See what other customers who have flown with United Airlines, American Airlines, and British Airways from Knoxville to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,916 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,916 reviews
United Airlines
7.4
Good
8,916 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,916 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
British Airways
6.7
Okay
7,267 reviews
United Airlines
7.4
Good
8,916 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Madrid round-trip?

    According to our current data, United Airlines ($562), British Airways ($594), and American Airlines ($594) offers the cheapest pricing from Knoxville to Madrid. United Airlines is currently priced 43% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Madrid that include hotel bookings?

    Yes. In addition to deals on Knoxville to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Madrid.

  • Can I find deals for business class flights from Knoxville to Madrid?

    Yes. Cheapflights offers flight deals from Knoxville to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Madrid (average of $543). Flying from Knoxville to Madrid in June is currently the most expensive (average of $1,053). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Segovia
Fuenlabrada

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Alternative routes for Knoxville to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Madrid flights
Memphis to Madrid flights

Top 3 airlines flying from Knoxville to Madrid

Discover the top 3 airlines that operate flights from Knoxville to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$562Average$875FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$594Average$800FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$594Average$1,117FlexibilityNo cancel feeOn-time71%

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