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Lyon

$487+ Cheap flights from St. Louis (STL) to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — LYS
oct. 16 — oct. 231
jue. 10/16
jue. 10/23
1 adult, Economy
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Cheap flight deals from St. Louis to Lyon

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Lyon (LYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 16, 2025.

Round-trip from

$655
(Kiwi.com)

One-way from

$487
(United Airlines)
From Lambert-St Louis to Lyon-Saint Exupéry
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One-way flight from Lambert-St Louis to Lyon-Saint Exupéry
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Find flight deals from St. Louis to Lyon

Cheapest flights from St. Louis to Lyon
Explore the most affordable flight options available from St. Louis to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/73:50 pmSTL - LYS
1 stop11h 15mLufthansa
mié. 11/126:25 amLYS - STL
1 stop14h 30mLufthansa
Deal found 9/15$655
This FlightHub deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/146:30 amSTL - LYS
2 stops21h 35mMultiple Airlines
mié. 11/196:25 amLYS - STL
1 stop14h 30mMultiple Airlines
Deal found 9/16$659
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/3012:31 pmSTL - LYS
2 stops23h 49mUnited Airlines
jue. 11/61:55 pmLYS - STL
2 stops32h 51mUnited Airlines
Deal found 9/15$664
This FlightHub deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/148:00 amSTL - LYS
2 stops20h 05mAir Canada
mié. 11/1910:45 amLYS - STL
2 stops35h 44mAir Canada
Deal found 9/16$666
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/143:50 pmSTL - LYS
1 stop15h 25mLufthansa
mié. 11/196:25 amLYS - STL
1 stop14h 30mLufthansa
Deal found 9/16$670
This United deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/73:14 pmSTL - LYS
2 stops19h 26mMultiple Airlines
mié. 11/126:25 amLYS - STL
1 stop14h 30mMultiple Airlines
Deal found 9/15$679
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/73:50 pmSTL - LYS
1 stop11h 15mUnited Airlines
mié. 11/126:25 amLYS - STL
1 stop14h 30mUnited Airlines
Deal found 9/15$683
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/204:05 pmSTL - LYS
2 stops36h 00mMultiple Airlines
vie. 11/286:25 amLYS - STL
1 stop14h 30mMultiple Airlines
Deal found 9/16$761
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/311:35 pmSTL - LYS
2 stops16h 50mUnited Airlines
vie. 11/76:25 amLYS - STL
1 stop14h 30mUnited Airlines
Deal found 9/16$779

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from St. Louis to Lyon that are best for you.

Fly from

St. Louis

Fly to

Lyon

Route

Depart

Return

Price

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

vie. 11/7

3:50 pm-10:05 am

1 stop11h 15m

Lyon-Saint Exupéry

mié. 11/12

6:25 am-1:55 pm

1 stop14h 30m

$655

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

vie. 11/14

6:30 am-11:05 am

2 stops21h 35m

Lyon-Saint Exupéry

mié. 11/19

6:25 am-1:55 pm

1 stop14h 30m

$659

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

jue. 10/30

12:31 pm-6:20 pm

2 stops23h 49m

Lyon-Saint Exupéry

jue. 11/6

1:55 pm-3:46 pm

2 stops32h 51m

$664

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

vie. 11/14

8:00 am-11:05 am

2 stops20h 05m

Lyon-Saint Exupéry

mié. 11/19

10:45 am-3:29 pm

2 stops35h 44m

$666

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

vie. 11/7

3:14 pm-5:40 pm

2 stops19h 26m

Lyon-Saint Exupéry

mié. 11/12

6:25 am-1:55 pm

1 stop14h 30m

$679

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

vie. 11/7

3:50 pm-10:05 am

1 stop11h 15m

Lyon-Saint Exupéry

mié. 11/12

6:25 am-1:55 pm

1 stop14h 30m

$683

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

jue. 11/20

4:05 pm-11:05 am

2 stops36h 00m

Lyon-Saint Exupéry

vie. 11/28

6:25 am-1:55 pm

1 stop14h 30m

$761

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

vie. 10/31

1:35 pm-12:25 pm

2 stops16h 50m

Lyon-Saint Exupéry

vie. 11/7

6:25 am-1:55 pm

1 stop14h 30m

$779

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

lun. 12/22

6:35 pm-12:25 pm

2 stops34h 50m

$487

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

mié. 12/17

5:11 pm-10:35 am

2 stops58h 24m

$614

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 19 results
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Best time to book a flight from St. Louis to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Lyon

What is the cheapest time of day to fly from STL to LYS?

Find hourly flight availability from St. Louis to Lyon. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 16, 2025.

One of the essential ways to save on airfare from St. Louis to Lyon is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 23% on airfare.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Lyon?

    Lufthansa, United Airlines, and Air Canada can get you from St. Louis to Lyon in just under 11h 15m. Your travel time can differ by up to 12h 34m. Airlines will cover a distance of 4602 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from St. Louis to Lyon that include hotel bookings?

    Yes. In addition to deals on St. Louis to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Lyon.

  • Can I find deals for business class flights from St. Louis to Lyon?

    Yes. Cheapflights offers flight deals from St. Louis to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Lyon?

    Currently, November is the cheapest month in which you can book a flight from St. Louis to Lyon (average of $703). Flying from St. Louis to Lyon in June is currently the most expensive (average of $1,199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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