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Lyon

$341+ Cheap flights from Missouri to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — LYS
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Missouri to Lyon

Cheapest flights from Missouri to Lyon
Explore the most affordable flight options available from Missouri to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:25 am
STL
-
LYS
2 stops21h 40m
United Airlines
Mon 3/96:25 am
LYS
-
STL
2 stops20h 42m
United Airlines
Deal found 2/2$552
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:17 am
MCI
-
LYS
2 stops22h 23m
Air Canada
Fri 5/82:05 pm
LYS
-
MCI
2 stops31h 21m
Air Canada
Deal found 2/2$578
This Air Canada deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:00 am
MCI
-
LYS
3 stops18h 40m
Multiple Airlines
Fri 5/82:05 pm
LYS
-
MCI
2 stops27h 28m
Multiple Airlines
Deal found 2/1$586
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:00 am
MCI
-
LYS
2 stops44h 40m
United Airlines
Wed 5/202:05 pm
LYS
-
MCI
2 stops40h 22m
United Airlines
Deal found 2/3$592
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:20 pm
MCI
-
LYS
2 stops24h 25m
British Airways
Mon 9/285:40 pm
LYS
-
MCI
2 stops35h 35m
British Airways
Deal found 2/2$673
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:00 am
STL
-
LYS
2 stops21h 05m
United Airlines
Sun 3/11:40 pm
LYS
-
STL
2 stops38h 25m
United Airlines
Deal found 1/31$728
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:32 am
MCI
-
LYS
2 stops23h 08m
United Airlines
Sun 3/11:40 pm
LYS
-
MCI
2 stops39h 19m
United Airlines
Deal found 2/2$733
This Air Canada deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:00 am
MCI
-
LYS
3 stops18h 40m
Multiple Airlines
Mon 9/281:55 pm
LYS
-
MCI
2 stops16h 57m
Multiple Airlines
Deal found 1/31$848
This Gotogate deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/194:05 pm
STL
-
LYS
2 stops14h 20m
Multiple Airlines
Thu 3/2610:40 am
LYS
-
STL
1 stop34h 15m
Multiple Airlines
Deal found 2/2$1,327
This Air Canada deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:00 am
MCI
-
LYS
3 stops18h 40m
Air Canada
Mon 9/286:45 am
LYS
-
MCI
3 stops21h 44m
Air Canada
Deal found 2/1$1,425
This Orbitz deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:50 pm
STL
-
LYS
2 stops19h 00m
Multiple Airlines
Tue 3/176:05 pm
LYS
-
STL
2 stops33h 02m
Multiple Airlines
Deal found 2/1$1,555
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:00 pm
STL
-
LYS
2 stops33h 05m
Lufthansa
Tue 3/173:05 pm
LYS
-
STL
1 stop29h 50m
Lufthansa
Deal found 2/1$1,739

Find flight deals from Missouri to Lyon

Keep the following information in mind while searching for Missouri to Lyon flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$552
(United Airlines)

One-way from

$341
(Iberia)
Provider with most accurate pricing for Lambert-St Louis-Lyon-Saint Exupéry flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Lyon-Saint Exupéry flights.
Search Deals
From Missouri to Lyon-Saint Exupéry
Search Deals
One-way flight from Missouri to Lyon-Saint Exupéry
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Missouri to Lyon that are best for you.

Fly from

Missouri

Fly to

Lyon

Route

Depart

Return

Price

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

Mon 3/2

6:25 am-11:05 am

2 stops21h 40m

Lyon-Saint Exupéry

Mon 3/9

6:25 am-9:07 pm

2 stops20h 42m

$552

Kansas CityLyon

MCI - LYS

MCILYS

Kansas City

Thu 4/30

6:17 am-11:40 am

2 stops22h 23m

Lyon-Saint Exupéry

Fri 5/8

2:05 pm-2:26 pm

2 stops31h 21m

$578

Kansas CityLyon

MCI - LYS

MCILYS

Kansas City

Thu 4/30

10:00 am-11:40 am

3 stops18h 40m

Lyon-Saint Exupéry

Fri 5/8

2:05 pm-10:33 am

2 stops27h 28m

$586

Kansas CityLyon

MCI - LYS

MCILYS

Kansas City

Sun 5/10

8:00 am-11:40 am

2 stops44h 40m

Lyon-Saint Exupéry

Wed 5/20

2:05 pm-11:27 pm

2 stops40h 22m

$592

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

Wed 2/25

7:00 am-11:05 am

2 stops21h 05m

Lyon-Saint Exupéry

Sun 3/1

1:40 pm-9:05 pm

2 stops38h 25m

$728

Kansas CityLyon

MCI - LYS

MCILYS

Kansas City

Wed 2/25

3:22 pm-5:40 pm

2 stops19h 18m

Lyon-Saint Exupéry

Sun 3/1

1:40 pm-9:59 pm

2 stops39h 19m

$733

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

Thu 3/19

2:00 pm-12:25 pm

2 stops16h 25m

Lyon-Saint Exupéry

Thu 3/26

9:35 am-10:50 pm

2 stops19h 15m

$748

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

Sat 3/14

6:50 pm-7:50 pm

2 stops19h 00m

Lyon-Saint Exupéry

Tue 3/17

6:05 pm-9:07 pm

2 stops33h 02m

$1,555

St. LouisLyon

STL - LYS

STLLYS

Lambert-St Louis

Sat 3/14

7:00 pm-10:05 am

2 stops33h 05m

Lyon-Saint Exupéry

Tue 3/17

3:05 pm-2:55 pm

1 stop29h 50m

$1,739

Kansas CityLyon

MCI - LYS

MCILYS

Kansas City

Thu 7/16

2:43 pm-8:50 pm

2 stops23h 07m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 12 results
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Best time to book a flight from Missouri to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Lyon
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lyon from Missouri?

    Most people fly into Lyon-Saint Exupéry (LYS) if they book a flight to Lyon from Missouri. Lyon-Saint Exupéry is conveniently located just 12.5 mi from Lyon’s city center.

  • How long is the flight from Missouri to Lyon?

    There are many flights that can get you from Missouri to Lyon in 16h 25m. Fly via United Airlines, Air Canada, or British Airways to get the fastest option. There are 4602 mi between Missouri and Lyon. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Lyon that include hotel bookings?

    Yes. In addition to deals on Missouri to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Lyon.

  • Can I find deals for business class flights from Missouri to Lyon?

    Yes. Cheapflights offers flight deals from Missouri to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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