How long is the flight from Indiana to Lyon?

A quick flight from Indiana to Lyon can take about 12h 30m. TAP AIR PORTUGAL provides one of the quickest options available for as low as $585. Indiana and Lyon are separated by a distance of 4360 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Indiana to Lyon one-way?

One-way options have recently been found by users for as low as $372 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include American Airlines from $457 and Delta from $472 one-way.

What is the cheapest month to book a flight from Indiana to Lyon?

Currently, November is the cheapest month in which you can book a flight from Indiana to Lyon (average of $703). Flying from Indiana to Lyon in June is currently the most expensive (average of $1,199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

In terms of precipitation, rainfall in Lyon ranges from 1.6 - 3.1 inches per month. October is typically the wettest month, when rainfall can reach 3.1 in. January is typically the driest time to visit Lyon when rainfall is around 1.6 in.

If weather is an important factor for your trip to Lyon, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What are the most popular routes from Indiana to Lyon?

When deciding which route to take from Indiana to Lyon consider Chicago O'Hare Intl - Lyon-Saint Exupéry, Chicago Midway - Lyon-Saint Exupéry or Cincinnati Cinci./N. Kentucky - Lyon-Saint Exupéry as they are the most popular.

What airport do you fly into for flights to Lyon from Indiana?

If you book a flight to Lyon from Indiana, you will be flying to Lyon-Saint Exupéry, which is the city’s only airport. Lyon-Saint Exupéry (LYS) is located 12.5 mi from the center of Lyon.

Can I find deals for flights from Indiana to Lyon that include hotel bookings?

Yes. In addition to deals on Indiana to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Indiana to Lyon?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Lyon.

Can I find deals for business class flights from Indiana to Lyon?

Yes. Cheapflights offers flight deals from Indiana to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$245+ Cheap Flights from Indiana to Lyon

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Indiana to Lyon with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to Lyon

Round-trip from	$415 (oojo)
One-way from	$245 (Kiwi.com)

From Indiana to Lyon-Saint Exupéry

Search Deals

One-way flight from Indiana to Lyon-Saint Exupéry

Search Deals

Find flight deals from Indiana to Lyon

Cheapest flights from Indiana to Lyon
Explore the most affordable flight options available from Indiana to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Sun 10/196:00 pmORD - LYS

1 stop16h 45mTAP AIR PORTUGAL

Tue 11/46:20 pmLYS - ORD

1 stop27h 40mTAP AIR PORTUGAL

Deal found 9/9

$414

Wed 12/37:10 pmORD - LYS

1 stop15h 25mTAP AIR PORTUGAL

Sat 12/136:15 pmLYS - ORD

1 stop27h 45mTAP AIR PORTUGAL

Deal found 9/10

$415

Wed 11/127:10 pmORD - LYS

1 stop15h 25mTAP AIR PORTUGAL

Tue 11/186:20 pmLYS - ORD

1 stop27h 40mTAP AIR PORTUGAL

Deal found 9/10

$422

Fri 12/58:15 pmORD - LYS

1 stop20h 40mTAP AIR PORTUGAL

Sat 12/136:15 pmLYS - ORD

1 stop27h 30mTAP AIR PORTUGAL

Deal found 9/11

$440

Wed 11/127:10 pmORD - LYS

1 stop15h 25mTAP AIR PORTUGAL

Sun 11/165:10 amLYS - ORD

1 stop16h 50mTAP AIR PORTUGAL

Deal found 9/10

$455

Sun 10/198:40 amORD - LYS

2 stops19h 05mMultiple Airlines

Tue 11/48:15 amLYS - ORD

2 stops18h 45mMultiple Airlines

Deal found 9/10

$554

Thu 11/2012:15 pmCVG - LYS

2 stops25h 10mScandinavian Airlines

Thu 12/48:10 pmLYS - CVG

2 stops31h 17mScandinavian Airlines

Deal found 9/9

$556

Sun 10/196:00 pmORD - LYS

1 stop11h 20mUnited Airlines

Tue 11/410:45 amLYS - ORD

2 stops17h 31mUnited Airlines

Deal found 9/9

$577

Wed 11/1211:00 amORD - LYS

2 stops17h 05mUnited Airlines

Thu 11/201:55 pmLYS - ORD

1 stop32h 00mUnited Airlines

Deal found 9/10

$580

Wed 10/83:35 pmORD - LYS

2 stops23h 00mMultiple Airlines

Wed 10/159:20 amLYS - ORD

1 stop15h 45mMultiple Airlines

Deal found 9/9

$584

Wed 11/123:35 pmORD - LYS

1 stop12h 30mUnited Airlines

Wed 11/196:25 amLYS - ORD

1 stop13h 45mUnited Airlines

Deal found 9/10

$585

Wed 11/129:00 amORD - LYS

2 stops19h 05mUnited Airlines

Tue 11/186:10 amLYS - ORD

1 stop16h 10mUnited Airlines

Deal found 9/10

$589

Best flights from Indiana to Lyon
Discover carefully curated flight deals from Indiana to Lyon that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Sun 10/196:00 pmORD - LYS

1 stop16h 45mTAP AIR PORTUGAL

Tue 11/46:20 pmLYS - ORD

1 stop27h 40mTAP AIR PORTUGAL

Deal found 9/9

$414

Sun 10/198:40 amORD - LYS

2 stops19h 05mMultiple Airlines

Tue 11/48:15 amLYS - ORD

2 stops18h 45mMultiple Airlines

Deal found 9/10

$554

Thu 11/2012:15 pmCVG - LYS

2 stops25h 10mScandinavian Airlines

Thu 12/48:10 pmLYS - CVG

2 stops31h 17mScandinavian Airlines

Deal found 9/9

$556

Wed 11/123:35 pmORD - LYS

1 stop12h 30mUnited Airlines

Wed 11/196:25 amLYS - ORD

1 stop13h 45mUnited Airlines

Deal found 9/10

$585

Sun 10/196:23 pmMDW - LYS

2 stops16h 22mDelta

Tue 11/46:55 amLYS - MDW

2 stops18h 30mDelta

Deal found 9/10

$639

Thu 11/66:20 pmCVG - LYS

2 stops34h 45mAir Canada

Sat 11/151:55 pmLYS - CVG

2 stops32h 46mAir Canada

Deal found 9/10

$688

Thu 11/62:06 pmCVG - LYS

2 stops16h 19mBritish Airways

Sat 11/159:45 pmLYS - CVG

1 stop27h 10mBritish Airways

Deal found 9/10

$731

Wed 11/127:10 pmORD - LYS

1 stop15h 25mTAP AIR PORTUGAL

Thu 11/206:20 pmLYS - ORD

1 stop27h 55mTAP AIR PORTUGAL

Deal found 9/10

$422

Wed 11/129:00 amORD - LYS

2 stops19h 05mUnited Airlines

Tue 11/186:10 amLYS - ORD

1 stop16h 10mUnited Airlines

Deal found 9/10

$589

Sat 11/157:20 pmORD - LYS

1 stop31h 45mScandinavian Airlines

Tue 11/188:10 pmLYS - ORD

1 stop27h 35mScandinavian Airlines

Deal found 9/10

$590

Tue 11/111:47 pmMDW - LYS

2 stops14h 18mDelta

Tue 11/186:55 amLYS - MDW

2 stops18h 13mDelta

Deal found 9/10

$639

Wed 11/1212:50 pmORD - LYS

1 stop15h 15mUnited Airlines

Fri 11/211:05 pmLYS - ORD

1 stop12h 20mUnited Airlines

Deal found 9/10

$596

Last-minute flights from Indiana to Lyon
Discover last-minute flight deals from Indiana to Lyon. Data last updated September 11, 2025 and is based on user searches.

Wed 10/83:35 pmORD - LYS

2 stops23h 00mMultiple Airlines

Wed 10/159:20 amLYS - ORD

1 stop15h 45mMultiple Airlines

Deal found 9/9

$584

Tue 10/1410:40 amORD - LYS

2 stops21h 20mMultiple Airlines

Tue 10/216:15 pmLYS - ORD

3 stops30h 18mMultiple Airlines

Deal found 9/10

$631

Sun 10/196:00 pmORD - LYS

1 stop16h 45mTAP AIR PORTUGAL

Tue 11/46:20 pmLYS - ORD

1 stop27h 40mTAP AIR PORTUGAL

Deal found 9/9

$414

Sun 10/198:40 amORD - LYS

2 stops19h 05mMultiple Airlines

Tue 11/48:15 amLYS - ORD

2 stops18h 45mMultiple Airlines

Deal found 9/10

$554

Sun 10/196:00 pmORD - LYS

1 stop11h 20mUnited Airlines

Tue 11/410:45 amLYS - ORD

2 stops17h 31mUnited Airlines

Deal found 9/9

$577

Sun 10/193:50 pmORD - LYS

2 stops14h 50mAir Canada

Tue 11/410:45 amLYS - ORD

2 stops15h 45mAir Canada

Deal found 9/11

$590

Sun 10/195:40 pmORD - LYS

2 stops15h 30mAmerican Airlines

Tue 11/46:10 amLYS - ORD

1 stop15h 20mAmerican Airlines

Deal found 9/11

$592

Sun 10/199:40 pmORD - LYS

1 stop12h 25mLufthansa

Tue 11/46:10 amLYS - ORD

1 stop14h 00mLufthansa

Deal found 9/10

$601

Sun 10/196:23 pmMDW - LYS

2 stops16h 22mDelta

Tue 11/46:55 amLYS - MDW

2 stops18h 30mDelta

Deal found 9/11

$639

Sun 10/266:18 pmFWA - LYS

2 stops18h 42mUnited Airlines

Sun 11/21:55 pmLYS - FWA

2 stops33h 48mUnited Airlines

Deal found 9/11

$694

Thu 10/306:04 pmCVG - LYS

2 stops20h 21mScandinavian Airlines

Sun 11/98:10 pmLYS - CVG

2 stops31h 20mScandinavian Airlines

Deal found 9/11

$605

Thu 10/305:50 pmCVG - LYS

2 stops19h 30mUnited Airlines

Tue 11/410:45 amLYS - CVG

2 stops16h 22mUnited Airlines

Deal found 9/10

$639

One-way flights from Indiana to Lyon
Search for one-way flight options from Indiana to Lyon. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Sun 9/286:00 pmORD - LYS

2 stops31h 40mMultiple Airlines

Deal found 9/8

$245

Thu 10/28:49 pmORD - LYS

2 stops37h 36mMultiple Airlines

Deal found 9/9

$254

Sun 9/286:00 pmORD - LYS

1 stop16h 45mTAP AIR PORTUGAL

Deal found 9/8

$372

Sat 10/2511:51 amCVG - LYS

3 stops42h 09mMultiple Airlines

Deal found 9/10

$385

Thu 9/186:21 pmORD - LYS

3 stops40h 04mMultiple Airlines

Deal found 9/10

$396

Tue 9/236:30 amORD - LYS

2 stops33h 05mMultiple Airlines

Deal found 9/9

$398

Wed 9/1711:45 amORD - LYS

3 stops51h 45mMultiple Airlines

Deal found 9/10

$432

Tue 12/236:00 pmORD - LYS

2 stops34h 05mAir Canada

Deal found 9/9

$438

Tue 9/1611:45 amORD - LYS

3 stops40h 10mMultiple Airlines

Deal found 9/10

$457

Wed 10/155:25 pmDAY - LYS

2 stops17h 20mAmerican Airlines

Deal found 9/9

$457

Sat 10/256:10 pmCVG - LYS

2 stops18h 25mDelta

Deal found 9/10

$472

Wed 10/152:47 pmDAY - LYS

3 stops23h 48mMultiple Airlines

Deal found 9/9

$657

Fly from

Fly to

Route

Depart

Return

Price

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 10/19

6:00 pm-5:45 pm

1 stop16h 45m

Lyon-Saint Exupéry

Tue 11/4

6:20 pm-3:00 pm

1 stop27h 40m

$414

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 11/12

7:10 pm-5:35 pm

1 stop15h 25m

Lyon-Saint Exupéry

Thu 11/20

6:20 pm-3:15 pm

1 stop27h 55m

$422

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sun 10/19

8:40 am-10:45 am

2 stops19h 05m

Lyon-Saint Exupéry

Tue 11/4

8:15 am-8:00 pm

2 stops18h 45m

$554

CincinnatiLyon

CVG - LYS

CVGLYS

Cincinnati Cinci./N. Kentucky

Thu 11/20

12:15 pm-7:25 pm

2 stops25h 10m

Lyon-Saint Exupéry

Thu 12/4

8:10 pm-9:27 pm

2 stops31h 17m

$556

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 11/12

3:35 pm-11:05 am

1 stop12h 30m

Lyon-Saint Exupéry

Wed 11/19

6:25 am-1:10 pm

1 stop13h 45m

$585

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 11/12

9:00 am-11:05 am

2 stops19h 05m

Lyon-Saint Exupéry

Tue 11/18

6:10 am-3:20 pm

1 stop16h 10m

$589

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Sat 11/15

7:20 pm-10:05 am

1 stop31h 45m

Lyon-Saint Exupéry

Tue 11/18

8:10 pm-4:45 pm

1 stop27h 35m

$590

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Wed 11/12

12:50 pm-11:05 am

1 stop15h 15m

Lyon-Saint Exupéry

Fri 11/21

1:05 pm-6:25 pm

1 stop12h 20m

$596

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Tue 11/11

9:50 pm-5:40 pm

1 stop12h 50m

Lyon-Saint Exupéry

Thu 11/20

1:55 pm-11:18 am

1 stop28h 23m

$598

ChicagoLyon

ORD - LYS

ORDLYS

Chicago O'Hare Intl

Mon 11/10

12:50 pm-10:05 am

2 stops14h 15m

Lyon-Saint Exupéry

Thu 11/20

1:55 pm-11:18 am

1 stop28h 23m

$603

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/8

Showing 1-10 of 43 results

...

Best time to book a flight from Indiana to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from Indiana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Lyon

What is the cheapest time of day to fly from IN to LYS?

When flying from Indiana to Lyon, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

What airport do you fly into for flights to Lyon from Indiana?
If you book a flight to Lyon from Indiana, you will be flying to Lyon-Saint Exupéry, which is the city’s only airport. Lyon-Saint Exupéry (LYS) is located 12.5 mi from the center of Lyon.
How long is the flight from Indiana to Lyon?
A quick flight from Indiana to Lyon can take about 12h 30m. TAP AIR PORTUGAL provides one of the quickest options available for as low as $585. Indiana and Lyon are separated by a distance of 4360 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Indiana to Lyon one-way?
One-way options have recently been found by users for as low as $372 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include American Airlines from $457 and Delta from $472 one-way.
What are the most popular routes from Indiana to Lyon?
When deciding which route to take from Indiana to Lyon consider Chicago O'Hare Intl - Lyon-Saint Exupéry, Chicago Midway - Lyon-Saint Exupéry or Cincinnati Cinci./N. Kentucky - Lyon-Saint Exupéry as they are the most popular.
Can I find deals for flights from Indiana to Lyon that include hotel bookings?
Yes. In addition to deals on Indiana to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Indiana to Lyon?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Lyon.
Can I find deals for business class flights from Indiana to Lyon?
Yes. Cheapflights offers flight deals from Indiana to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Indiana to Lyon?
Currently, November is the cheapest month in which you can book a flight from Indiana to Lyon (average of $703). Flying from Indiana to Lyon in June is currently the most expensive (average of $1,199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Annemasse

Huez

Browse thousands of different options on Cheapflights for your next trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$245+ Cheap flights from Indiana to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Indiana to Lyon with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Indiana to Lyon

Keep the following information in mind while searching for Indiana to Lyon flight deals. Data was last updated September 11, 2025.

Round-trip from

One-way from

Find flight deals from Indiana to Lyon

Cheapest flights from Indiana to LyonExplore the most affordable flight options available from Indiana to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Indiana to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Indiana to Lyon that are best for you.

Best time to book a flight from Indiana to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from Indiana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Lyon

What is the cheapest time of day to fly from IN to LYS?

Find hourly flight availability from Indiana to Lyon. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Lyon from Indiana?

How long is the flight from Indiana to Lyon?

What are the cheapest airlines to fly from Indiana to Lyon one-way?

What are the most popular routes from Indiana to Lyon?

Can I find deals for flights from Indiana to Lyon that include hotel bookings?

How can I find direct flights from Indiana to Lyon?

Can I find deals for business class flights from Indiana to Lyon?

What is the cheapest month to book a flight from Indiana to Lyon?

Traveling to a place near Lyon?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Lyon

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Indiana to Lyon
Explore the most affordable flight options available from Indiana to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.