How long is the flight from Santa Ana, California to Louisville?

Departing from Santa Ana, California to Louisville will take you 6h 36m. Santa Ana, California and Louisville are separated by a distance of 1814 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Santa Ana, California to Louisville round-trip?

Our cheapest airline available from Santa Ana, California to Louisville is Spirit Airlines. Our recent data shows that you can find tickets from as low as $114 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $260 and $324 round-trip. Spirit Airlines is currently priced 77% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Santa Ana, California to Louisville one-way?

For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $171. Users have also found prices from $171 and $177 on United Airlines and Southwest, respectively.

In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.

If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).

What are the most popular airlines that fly from Santa Ana, California to Louisville?

American Airlines, Southwest and Delta are the most popular airlines when flying from Santa Ana, California to Louisville.

What is the cheapest time of day to fly from SNA to SDF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Ana, California to Louisville as you normally would.

Most accurate provider : When it comes to deals on Santa Ana, California-Louisville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Ana, California-Louisville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Louisville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Santa Ana, California-Louisville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Santa Ana to Louisville that include hotel bookings?

Yes. In addition to deals on Santa Ana to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to Louisville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Louisville.

Can I find deals for business class flights from Santa Ana to Louisville?

Yes. Cheapflights offers flight deals from Santa Ana to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$139+ Flights from Santa Ana, CA to Louisville

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Santa Ana to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Santa Ana to Louisville

Cheapest flights from Santa Ana to Louisville
Explore the most affordable flight options available from Santa Ana to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Wed 12/316:45 amSNA - SDF

1 stop12h 45mUnited Airlines

Fri 1/25:40 amSDF - SNA

1 stop8h 55mUnited Airlines

Deal found 12/26

$931

Mon 12/297:25 amSNA - SDF

1 stop6h 35mSouthwest

Wed 12/315:50 pmSDF - SNA

1 stop6h 25mSouthwest

Deal found 12/25

$1,057

Wed 12/316:45 amSNA - SDF

2 stops12h 09mAlaska Airlines

Fri 1/26:27 amSDF - SNA

2 stops12h 47mAlaska Airlines

Deal found 12/26

$2,170

Best flights from Santa Ana to Louisville
Discover carefully curated flight deals from Santa Ana to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Wed 1/211:20 pmSNA - SDF

2 stops22h 21mSpirit Airlines

Sun 1/253:36 pmSDF - SNA

2 stops23h 49mSpirit Airlines

Deal found 12/26

$282

Sat 1/1712:23 pmSNA - SDF

1 stop6h 36mUnited Airlines

Sun 1/186:00 amSDF - SNA

1 stop8h 21mUnited Airlines

Deal found 12/27

$391

Wed 2/411:55 amSNA - SDF

1 stop8h 55mDelta

Fri 2/65:35 amSDF - SNA

2 stops13h 59mDelta

Deal found 12/26

$392

Wed 1/217:50 amSNA - SDF

1 stop6h 43mAmerican Airlines

Sun 1/258:07 amSDF - SNA

1 stop7h 57mAmerican Airlines

Deal found 12/26

$402

Wed 1/218:00 amSNA - SDF

2 stops9h 28mUnited Airlines

Sun 1/259:00 amSDF - SNA

1 stop7h 11mUnited Airlines

Deal found 12/26

$407

Thu 2/197:45 amSNA - SDF

1 stop8h 12mAmerican Airlines

Sun 2/227:51 amSDF - SNA

1 stop9h 04mAmerican Airlines

Deal found 12/27

$418

Last-minute flights from Santa Ana to Louisville
Discover last-minute flight deals from Santa Ana to Louisville. Data last updated December 28, 2025 and is based on user searches.

Sat 1/104:37 pmSNA - SDF

2 stops19h 04mSpirit Airlines

Wed 1/141:55 pmSDF - SNA

3 stops25h 30mSpirit Airlines

Deal found 12/26

$460

Sat 1/1012:59 pmSNA - SDF

1 stop7h 56mDelta

Wed 1/146:00 amSDF - SNA

1 stop8h 49mDelta

Deal found 12/26

$557

Mon 1/124:37 pmSNA - SDF

2 stops19h 04mSpirit Airlines

Fri 1/161:55 pmSDF - SNA

3 stops28h 47mSpirit Airlines

Deal found 12/27

$536

Sat 1/1710:51 amSNA - SDF

1 stop6h 37mUnited Airlines

Sun 1/186:12 pmSDF - SNA

1 stop7h 12mUnited Airlines

Deal found 12/26

$391

Wed 1/211:20 pmSNA - SDF

2 stops22h 21mSpirit Airlines

Sun 1/253:36 pmSDF - SNA

2 stops23h 49mSpirit Airlines

Deal found 12/26

$282

Wed 1/217:50 amSNA - SDF

1 stop6h 43mAmerican Airlines

Sun 1/258:07 amSDF - SNA

1 stop7h 57mAmerican Airlines

Deal found 12/26

$402

Wed 1/218:00 amSNA - SDF

2 stops9h 28mUnited Airlines

Sun 1/259:00 amSDF - SNA

1 stop7h 11mUnited Airlines

Deal found 12/26

$407

One-way flights from Santa Ana to Louisville
Search for one-way flight options from Santa Ana to Louisville. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Mon 1/264:37 pmSNA - SDF

2 stops19h 04mSpirit Airlines

Deal found 12/27

$139

Fri 2/274:37 pmSNA - SDF

2 stops15h 28mSpirit Airlines

Deal found 12/27

$142

Wed 2/251:20 pmSNA - SDF

2 stops22h 18mSpirit Airlines

Deal found 12/27

$145

Sat 2/286:45 amSNA - SDF

3 stops46h 55mMultiple Airlines

Deal found 12/26

$146

Sun 3/17:10 pmSNA - SDF

2 stops14h 11mMultiple Airlines

Deal found 12/27

$150

Thu 1/226:45 amSNA - SDF

3 stops32h 19mMultiple Airlines

Deal found 12/26

$154

Tue 2/241:20 pmSNA - SDF

3 stops20h 01mMultiple Airlines

Deal found 12/27

$160

Fri 2/277:07 pmSNA - SDF

3 stops39h 19mMultiple Airlines

Deal found 12/27

$163

Wed 1/286:45 amSNA - SDF

3 stops28h 56mSpirit Airlines

Deal found 12/26

$165

Mon 1/266:56 pmSNA - SDF

3 stops39h 04mMultiple Airlines

Deal found 12/27

$166

Thu 2/266:45 amSNA - SDF

3 stops22h 55mMultiple Airlines

Deal found 12/27

$170

Find flight deals from Santa Ana to Louisville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$282 (Mytrip)
One-way from	$139 (Trip.com)
Popular in	November
Cheapest in	May
Average price	$480

Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Louisville Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Louisville Intl flights.

Search Deals

From Santa Ana J. Wayne/Orange Cnty to Louisville Intl

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to Louisville Intl

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($40 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Wed 1/21

1:20 pm-2:41 pm

2 stops22h 21m

Louisville Intl

Sun 1/25

3:36 pm-12:25 pm

2 stops23h 49m

$282

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

12:23 pm-9:59 pm

1 stop6h 36m

Louisville Intl

Sun 1/18

6:00 am-11:21 am

1 stop8h 21m

$391

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Wed 2/4

11:55 am-11:50 pm

1 stop8h 55m

Louisville Intl

Fri 2/6

5:35 am-4:34 pm

2 stops13h 59m

$392

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Wed 1/21

7:50 am-5:33 pm

1 stop6h 43m

Louisville Intl

Sun 1/25

8:07 am-1:04 pm

1 stop7h 57m

$402

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Wed 1/21

8:00 am-8:28 pm

2 stops9h 28m

Louisville Intl

Sun 1/25

9:00 am-1:11 pm

1 stop7h 11m

$407

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Thu 2/19

7:45 am-6:57 pm

1 stop8h 12m

Louisville Intl

Sun 2/22

7:51 am-1:55 pm

1 stop9h 04m

$418

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Fri 2/27

4:37 pm-11:05 am

2 stops15h 28m

$142

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Mon 3/2

8:58 am-2:38 pm

2 stops26h 40m

$145

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Mon 2/23

1:20 pm-2:38 pm

2 stops22h 18m

$145

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Fri 2/27

4:02 pm-11:05 am

2 stops16h 03m

$145

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 14 results

Compare providers for flights from Santa Ana to Louisville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Louisville in December.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Santa Ana, California-Louisville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Ana, California-Louisville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Louisville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Santa Ana, California-Louisville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Louisville

What is the cheapest month to book a flight from Santa Ana, California to Louisville?

Currently, June is the cheapest month in which you can book a flight from Santa Ana, California to Louisville (average of $71). Flying from Santa Ana, California to Louisville in November is currently the most expensive (average of $185). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Southwest

8.0

Very good

4,256 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Delta

7.9

Good

8,019 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

United Airlines

7.4

Good

9,113 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

American Airlines

7.2

Good

11,073 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Spirit Airlines

6.3

Okay

8,211 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

How long is the flight from Santa Ana, California to Louisville?
Departing from Santa Ana, California to Louisville will take you 6h 36m. Santa Ana, California and Louisville are separated by a distance of 1814 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Santa Ana, California to Louisville round-trip?
Our cheapest airline available from Santa Ana, California to Louisville is Spirit Airlines. Our recent data shows that you can find tickets from as low as $114 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $260 and $324 round-trip. Spirit Airlines is currently priced 77% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Santa Ana, California to Louisville one-way?
For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $171. Users have also found prices from $171 and $177 on United Airlines and Southwest, respectively.
Can I find deals for flights from Santa Ana to Louisville that include hotel bookings?
Yes. In addition to deals on Santa Ana to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to Louisville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Louisville.
Can I find deals for business class flights from Santa Ana to Louisville?
Yes. Cheapflights offers flight deals from Santa Ana to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana, California to Louisville?
Currently, June is the cheapest month in which you can book a flight from Santa Ana, California to Louisville (average of $71). Flying from Santa Ana, California to Louisville in November is currently the most expensive (average of $185). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Shepherdsville

Jeffersonville

Elizabethtown

Corydon

Bardstown

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santa Ana to Louisville

Los Angeles to Nashville flights

San Francisco to Nashville flights

Ontario to Nashville flights

San Diego to Nashville flights

Los Angeles to Cincinnati flights

Sacramento to Nashville flights

Santa Ana to Nashville flights

Burbank to Nashville flights

Fresno to Nashville flights

Las Vegas to Nashville flights

San Francisco to Cincinnati flights

Los Angeles to Louisville flights

Los Angeles to Knoxville flights

San Francisco to Knoxville flights

San Jose to Nashville flights

Ontario to Knoxville flights

Long Beach to Nashville flights

Palm Springs to Nashville flights

San Diego to Cincinnati flights

Ontario to Louisville flights

Ontario to Cincinnati flights

Burbank to Cincinnati flights

Las Vegas to Cincinnati flights

San Francisco to Louisville flights

Santa Ana to Cincinnati flights

Santa Barbara to Nashville flights

San Diego to Knoxville flights

San Diego to Lexington flights

Las Vegas to Louisville flights

San Jose to Knoxville flights

Sacramento to Knoxville flights

Burbank to Knoxville flights

Las Vegas to Knoxville flights

Oakland to Nashville flights

Sacramento to Cincinnati flights

Los Angeles to Lexington flights

Sacramento to Louisville flights

San Diego to Louisville flights

San Jose to Cincinnati flights

Ontario to Lexington flights

Reno to Nashville flights

San Jose to Louisville flights

San Luis Obispo to Nashville flights

Santa Ana to Knoxville flights

Monterey to Nashville flights

Oakland to Cincinnati flights

Santa Ana to Lexington flights

Medford to Nashville flights

Palm Springs to Knoxville flights

Burbank to Louisville flights

Complete your trip

Louisville car rentals

Cincinnati Cinci./N. Kentucky Airport car rentals

Louisville Intl Airport car rentals

Lexington Blue Grass Airport car rentals

Evansville Dress Regional Airport car rentals

Cincinnati Airport car rentals

Owensboro Daviess County Airport car rentals

Lexington car rentals

Paducah car rentals

Beechmont car rentals

Centrum car rentals

Other flights to Louisville

Top 5 airlines flying from Santa Ana to Louisville

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$114	Average$237	FlexibilityNo cancel fee	On-time65%
United Airlines	Cheapest$260	Average$455	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$324	Average$478	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$342	Average$452	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$402	Average$522	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$139+ Cheap flights from Santa Ana, CA to Louisville (SNA - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to Louisville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santa Ana to Louisville

Cheapest flights from Santa Ana to LouisvilleExplore the most affordable flight options available from Santa Ana to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Santa Ana to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Santa Ana to Louisville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Louisville that are best for you.

Compare providers for flights from Santa Ana to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Louisville in December.

Best time to book a flight from Santa Ana to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Louisville

What is the cheapest month to book a flight from Santa Ana, California to Louisville?

Reviews of airlines servicing Louisville

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santa Ana, California to Louisville?

What are the cheapest airlines flying from Santa Ana, California to Louisville round-trip?

What are the cheapest airlines to fly from Santa Ana, California to Louisville one-way?

Can I find deals for flights from Santa Ana to Louisville that include hotel bookings?

How can I find direct flights from Santa Ana to Louisville?

Can I find deals for business class flights from Santa Ana to Louisville?

What is the cheapest month to book a flight from Santa Ana, California to Louisville?

Traveling to a place near Louisville?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Louisville

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Santa Ana to Louisville

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Santa Ana to Louisville
Explore the most affordable flight options available from Santa Ana to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.