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$490+ Cheap flights from Panama City (PTY) to Louisville (SDF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Panama City to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$490
(American Airlines)

Popular in

January

Cheapest in

February

Average price

$497
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
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From Panama City Tocumen Intl to Louisville Intl
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Highest demand for flights based on searches. 16% potential increase in price ($111 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to Louisville

Cheapest flights from Panama City to Louisville
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/153:40 pmPTY - SDF
2 stops24h 37mAmerican Airlines
Fri 12/126:21 pmSDF - PTY
2 stops21h 04mAmerican Airlines
Deal found 4/28$503
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/12:12 pmPTY - SDF
1 stop7h 18mDelta
Wed 11/56:00 amSDF - PTY
1 stop7h 47mDelta
Deal found 4/29$505
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/274:40 pmPTY - SDF
2 stops20h 20mUnited Airlines
Thu 1/87:30 amSDF - PTY
2 stops12h 32mUnited Airlines
Deal found 4/28$527
This Avianca Connect deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:19 amPTY - SDF
2 stops15h 44mMultiple Airlines
Wed 11/59:06 amSDF - PTY
2 stops11h 54mMultiple Airlines
Deal found 4/29$660

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Panama City

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 8/15

3:40 pm-5:17 pm

2 stops24h 37m

Louisville Intl

Fri 12/12

6:21 pm-3:25 pm

2 stops21h 04m

$503

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 5/17

2:13 pm-12:05 am

1 stop8h 52m

Louisville Intl

Sat 5/24

1:05 pm-7:53 pm

1 stop7h 48m

$524

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 5/17

10:00 am-10:30 pm

2 stops11h 30m

Louisville Intl

Sat 5/24

3:38 pm-6:37 pm

1 stop27h 59m

$563

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Panama City to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Louisville in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Louisville flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Panama City-Louisville flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Panama City-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Louisville flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Louisville

What is the cheapest month to book a flight from Panama City to Louisville?

Currently, January is the cheapest month in which you can book a flight from Panama City to Louisville (average of $299). Flying from Panama City to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SDF?

Find hourly flight availability from Panama City to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

One of the essential ways to save on airfare from Panama City to Louisville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 10% on airfare.

Rainfall in Louisville by month

Plan your trip to Louisville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.

Temperature in Louisville by month

Plan your trip to Louisville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated April 30, 2025.
Delta
8.0
Very good
7,936 reviews

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,936 reviews

Overall

8.0

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Louisville round-trip?

    Flying on American Airlines is currently your cheapest option to Louisville, with prices starting at $490. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $501 and $524, respectively. You may be able to fly from Panama City to Louisville for 15% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama City to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Louisville.

  • Can I find deals for business class flights from Panama City to Louisville?

    Yes. Cheapflights offers flight deals from Panama City to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Louisville (average of $299). Flying from Panama City to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Jeffersonville
Corydon
Elizabethtown
Bardstown

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Alternative routes for Panama City to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Nashville flights
Panama City to Cincinnati flights

Top 3 airlines flying from Panama City to Louisville

Discover the top 3 airlines that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$323Average$557FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$370Average$601FlexibilityNo cancel feeOn-time71%
DeltaCheapest$426Average$504FlexibilityNo cancel feeOn-timeN/A

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