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$260+ Cheap flights from Panama City (PTY) to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Panama City to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$449
(United Airlines)

One-way from

$260
(Delta)

Popular in

January

Cheapest in

February

Average price

$620
From Panama City Tocumen Intl to Louisville Intl
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One-way flight from Panama City Tocumen Intl to Louisville Intl
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Highest demand for flights based on searches. 14% potential increase in price ($99 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Panama City to Louisville

Cheapest flights from Panama City to Louisville
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/13:30 pmPTY - SDF
2 stops20h 51mUnited Airlines
Tue 10/289:00 amSDF - PTY
2 stops10h 38mUnited Airlines
Deal found 7/30$449
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:10 pmPTY - SDF
1 stop8h 42mDelta
Fri 9/196:00 amSDF - PTY
1 stop7h 55mDelta
Deal found 7/29$451
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/133:31 pmPTY - SDF
1 stop7h 27mAmerican Airlines
Sat 9/206:31 amSDF - PTY
1 stop9h 00mAmerican Airlines
Deal found 7/30$460
This Avianca Connect deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:25 amPTY - SDF
2 stops18h 03mMultiple Airlines
Sat 9/208:30 amSDF - PTY
2 stops13h 40mMultiple Airlines
Deal found 7/30$498

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Panama City

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 10/1

3:30 pm-1:21 pm

2 stops20h 51m

Louisville Intl

Tue 10/28

9:00 am-6:38 pm

2 stops10h 38m

$449

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 9/12

2:10 pm-11:52 pm

1 stop8h 42m

Louisville Intl

Fri 9/19

6:00 am-12:55 pm

1 stop7h 55m

$451

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 9/13

3:31 pm-11:58 pm

1 stop7h 27m

Louisville Intl

Sat 9/20

6:31 am-2:31 pm

1 stop9h 00m

$460

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 9/12

3:25 am-10:28 pm

2 stops18h 03m

Louisville Intl

Sat 9/20

8:30 am-9:10 pm

2 stops13h 40m

$498

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 9/12

2:10 pm-11:52 pm

1 stop8h 42m

$260

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 9/12

3:30 pm-10:00 am

2 stops17h 30m

$265

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 9/11

3:20 am-10:28 pm

2 stops18h 08m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Panama City to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Louisville

What is the cheapest month to book a flight from Panama City to Louisville?

Currently, January is the cheapest month in which you can book a flight from Panama City to Louisville (average of $299). Flying from Panama City to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SDF?

Find hourly flight availability from Panama City to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

One of the essential ways to save on airfare from Panama City to Louisville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 10% on airfare.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated July 30, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Panama City to Louisville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Louisville round-trip?

    Flying on United Airlines is currently your cheapest option to Louisville, with prices starting at $449. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $451 and $460, respectively. You may be able to fly from Panama City to Louisville for 23% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama City to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Louisville.

  • Can I find deals for business class flights from Panama City to Louisville?

    Yes. Cheapflights offers flight deals from Panama City to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Louisville (average of $299). Flying from Panama City to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Alternative routes for Panama City to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Nashville flights
Panama City to Cincinnati flights

Top 3 airlines flying from Panama City to Louisville

Discover the top 3 airlines that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$323Average$557FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$370Average$627FlexibilityNo cancel feeOn-time71%
DeltaCheapest$426Average$504FlexibilityNo cancel feeOn-timeN/A

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