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$458+ Cheap flights from Panama City (PTY) to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Panama City to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$458
(United Airlines)

One-way from

$458

Popular in

January

Cheapest in

February

Average price

$640
From Panama City Tocumen Intl to Louisville Intl
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One-way flight from Panama City Tocumen Intl to Louisville Intl
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Highest demand for flights based on searches. 14% potential increase in price ($101 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($44 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Louisville

Cheapest flights from Panama City to Louisville
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/203:15 pmPTY - SDF
2 stops17h 08mAmerican Airlines
dom. 11/24:26 pmSDF - PTY
2 stops21h 23mAmerican Airlines
Deal found 9/10$465
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/22:10 pmPTY - SDF
1 stop8h 42mDelta
mar. 10/286:00 amSDF - PTY
1 stop7h 56mDelta
Deal found 9/11$569
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/23:31 pmPTY - SDF
2 stops23h 33mAmerican Airlines
mar. 10/286:48 pmSDF - PTY
2 stops20h 15mAmerican Airlines
Deal found 9/11$582
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/153:31 pmPTY - SDF
2 stops21h 23mAmerican Airlines
mié. 9/176:12 pmSDF - PTY
2 stops21h 19mAmerican Airlines
Deal found 9/11$670
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/203:30 pmPTY - SDF
1 stop27h 27mUnited Airlines
dom. 11/23:35 pmSDF - PTY
1 stop28h 03mUnited Airlines
Deal found 9/11$728
This Avianca Connect deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/143:20 amPTY - SDF
2 stops17h 44mMultiple Airlines
mié. 9/1710:14 amSDF - PTY
2 stops15h 31mMultiple Airlines
Deal found 9/11$821

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Panama City

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

vie. 3/6

10:00 am-7:25 pm

1 stop9h 25m

Louisville Intl

mar. 3/10

7:05 am-6:38 pm

1 stop12h 33m

$458

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

lun. 10/20

3:15 pm-12:36 am

1 stop8h 21m

Louisville Intl

dom. 11/2

4:26 pm-1:49 pm

2 stops21h 23m

$465

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

jue. 10/2

2:10 pm-11:52 pm

1 stop8h 42m

Louisville Intl

mar. 10/28

7:09 am-12:56 pm

1 stop6h 47m

$569

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

jue. 10/2

10:00 am-10:01 am

2 stops23h 01m

Louisville Intl

mar. 10/28

7:00 am-6:38 pm

2 stops12h 38m

$569

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

vie. 1/9

4:40 pm-12:17 am

1 stop7h 37m

$467

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

mar. 1/6

2:45 pm-2:29 pm

2 stops23h 44m

$479

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

mié. 1/7

4:40 pm-12:17 am

1 stop7h 37m

$511

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

lun. 1/5

4:56 pm-1:12 pm

2 stops20h 16m

$579

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

lun. 1/5

12:03 pm-8:03 pm

1 stop8h 00m

$642

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

mar. 1/6

12:03 pm-11:45 pm

3 stops35h 42m

$645

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Panama City to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Louisville

What is the cheapest month to book a flight from Panama City to Louisville?

Currently, January is the cheapest month in which you can book a flight from Panama City to Louisville (average of $299). Flying from Panama City to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SDF?

Find hourly flight availability from Panama City to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

One of the essential ways to save on airfare from Panama City to Louisville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 10% on airfare.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated septiembre 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Panama City to Louisville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Louisville?

    For as low as $458, United Airlines can have you in Louisville from Panama City in 9h 25m. There are 2048 mi between Panama City and Louisville.

  • What are the cheapest airlines flying from Panama City to Louisville round-trip?

    Flying on Delta is currently your cheapest option to Louisville, with prices starting at $338. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $366 and $370, respectively. You may be able to fly from Panama City to Louisville for 43% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama City to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Louisville.

  • Can I find deals for business class flights from Panama City to Louisville?

    Yes. Cheapflights offers flight deals from Panama City to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Louisville (average of $299). Flying from Panama City to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Alternative routes for Panama City to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Nashville flights
Panama City to Cincinnati flights

Top 3 airlines flying from Panama City to Louisville

Discover the top 3 airlines that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$338Average$526FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$366Average$557FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$370Average$627FlexibilityNo cancel feeOn-time71%

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