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$96+ Cheap flights from Mississippi to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SDF
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Mississippi to Louisville

Keep the following information in mind while searching for Mississippi to Louisville flight deals. Data was last updated August 18, 2025.

Round-trip from

$224
(American Airlines)

One-way from

$96
(Mytrip)

Popular in

April

Cheapest in

August

Average price

$302
From Mississippi to Louisville Intl
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One-way flight from Mississippi to Louisville Intl
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Highest demand for flights based on searches. 36% potential increase in price ($264 potential increase over avg. RT price).
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Cheapest flight prices on average. 21% potential price decrease ($81 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Mississippi to Louisville

Cheapest flights from Mississippi to Louisville
Explore the most affordable flight options available from Mississippi to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/301:34 pmGPT - SDF
1 stop5h 28mAmerican Airlines
Mon 9/86:44 pmSDF - GPT
1 stop5h 48mAmerican Airlines
Deal found 8/17$224
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:50 pmMOB - SDF
1 stop6h 10mAmerican Airlines
Sat 11/227:31 pmSDF - MOB
1 stop5h 25mAmerican Airlines
Deal found 8/17$249
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:01 pmBTR - SDF
1 stop3h 51mDelta
Mon 9/2912:48 pmSDF - BTR
1 stop4h 04mDelta
Deal found 8/18$249
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:18 pmBTR - SDF
1 stop7h 07mAmerican Airlines
Sat 11/18:22 amSDF - BTR
2 stops10h 48mAmerican Airlines
Deal found 8/17$254
This Mytrip deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/318:37 amMEM - SDF
1 stop9h 16mMultiple Airlines
Thu 9/410:14 amSDF - MEM
1 stop10h 16mMultiple Airlines
Deal found 8/16$274
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2010:54 amMEM - SDF
1 stop5h 40mAmerican Airlines
Sun 9/216:00 amSDF - MEM
1 stop6h 45mAmerican Airlines
Deal found 8/18$294
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:32 pmBTR - SDF
1 stop4h 27mAmerican Airlines
Mon 9/156:44 pmSDF - BTR
1 stop5h 27mAmerican Airlines
Deal found 8/17$294
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/98:32 amMEM - SDF
1 stop8h 31mMultiple Airlines
Sat 10/116:58 pmSDF - MEM
1 stop13h 29mMultiple Airlines
Deal found 8/17$304
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:00 amMOB - SDF
1 stop5h 30mUnited Airlines
Mon 8/259:40 amSDF - MOB
1 stop7h 31mUnited Airlines
Deal found 8/17$324
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:00 pmBTR - SDF
1 stop3h 56mDelta
Tue 11/252:59 pmSDF - BTR
1 stop5h 59mDelta
Deal found 8/18$324
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:34 pmGPT - SDF
1 stop4h 25mAmerican Airlines
Mon 9/156:44 pmSDF - GPT
1 stop5h 48mAmerican Airlines
Deal found 8/17$324
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2412:15 pmBTR - SDF
2 stops8h 21mAmerican Airlines
Mon 9/297:09 pmSDF - BTR
1 stop4h 57mAmerican Airlines
Deal found 8/18$327

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Mississippi to Louisville that are best for you.

Fly from

Mississippi

Fly to

Louisville

Route

Depart

Return

Price

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 8/30

1:34 pm-8:02 pm

1 stop5h 28m

Louisville Intl

Mon 9/8

6:44 pm-11:32 pm

1 stop5h 48m

$224

MobileLouisville

MOB - SDF

MOBSDF

Mobile

Fri 2/6

12:55 pm-6:49 pm

1 stop4h 54m

Louisville Intl

Sun 2/8

7:05 am-11:36 am

1 stop5h 31m

$249

Baton RougeLouisville

BTR - SDF

BTRSDF

Baton Rouge Ryan

Wed 9/24

7:01 pm-11:52 pm

1 stop3h 51m

Louisville Intl

Mon 9/29

12:48 pm-3:52 pm

1 stop4h 04m

$249

MobileLouisville

MOB - SDF

MOBSDF

Mobile

Thu 11/20

2:50 pm-10:00 pm

1 stop6h 10m

Louisville Intl

Sat 11/22

7:31 pm-11:56 pm

1 stop5h 25m

$249

Baton RougeLouisville

BTR - SDF

BTRSDF

Baton Rouge Ryan

Thu 9/11

4:39 pm-11:52 pm

1 stop6h 13m

Louisville Intl

Sun 9/14

6:00 am-9:07 am

1 stop4h 07m

$249

Baton RougeLouisville

BTR - SDF

BTRSDF

Baton Rouge Ryan

Fri 10/31

2:18 pm-10:25 pm

1 stop7h 07m

Louisville Intl

Sat 11/1

12:21 pm-6:10 pm

1 stop6h 49m

$249

Baton RougeLouisville

BTR - SDF

BTRSDF

Baton Rouge Ryan

Wed 9/24

5:30 am-1:54 pm

1 stop7h 24m

Louisville Intl

Mon 9/29

6:44 pm-11:11 pm

1 stop5h 27m

$249

MobileLouisville

MOB - SDF

MOBSDF

Mobile

Fri 2/6

5:23 am-5:55 pm

2 stops11h 32m

Louisville Intl

Sun 2/8

7:39 am-11:45 am

1 stop5h 06m

$254

MobileLouisville

MOB - SDF

MOBSDF

Mobile

Tue 9/2

8:00 am-2:50 pm

1 stop5h 50m

Louisville Intl

Sat 9/6

3:35 pm-7:41 pm

1 stop5h 06m

$259

MobileLouisville

MOB - SDF

MOBSDF

Mobile

Tue 9/2

5:07 pm-11:08 pm

1 stop5h 01m

Louisville Intl

Sat 9/6

7:35 am-4:52 pm

2 stops10h 17m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Louisville

What is the cheapest month to book a flight from Mississippi to Louisville?

Currently, January is the cheapest month in which you can book a flight from Mississippi to Louisville (average of $299). Flying from Mississippi to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SDF?

Find hourly flight availability from Mississippi to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Louisville as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Mississippi?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Louisville from Mississippi.

  • How long is the flight from Mississippi to Louisville?

    Departing from Mississippi to Louisville will take you 3h 51m. There are 611 mi between Mississippi and Louisville. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Louisville one-way?

    One-way options have recently been found by users for as low as $169 on Delta. Other airlines that offer cheap prices include American Airlines from $184 and United Airlines from $209 one-way.

  • What are the most popular routes from Mississippi to Louisville?

    While some choose either Gulfport Biloxi Regional - Louisville Intl or Jackson-Evers Intl - Louisville Intl, Baton Rouge Ryan - Louisville Intl is the most popular route from Mississippi to Louisville.

  • Can I find deals for flights from Mississippi to Louisville that include hotel bookings?

    Yes. In addition to deals on Mississippi to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Louisville.

  • Can I find deals for business class flights from Mississippi to Louisville?

    Yes. Cheapflights offers flight deals from Mississippi to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Mississippi to Louisville (average of $299). Flying from Mississippi to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Alternative routes for Mississippi to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Louisville

Discover the top 2 airlines that operate flights from Mississippi to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$219Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$487FlexibilityNo cancel feeOn-time71%

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