It’s generally more expensive to depart on a Saturday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.
It’s optimal to fly from Reno to Loreto in the morning. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight at noon.
Due to multiple factors, expect to potentially pay more when booking in October. For low rates, December can be a great choice for travel to Loreto. Flights to Loreto from Reno in December are about $468 on average during December, but can be found for as low as $181.