$507+ Cheap flights from Des Moines (DSM) to Lisbon (LIS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LIS
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Lisbon with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Lisbon
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Cheapest flights from Des Moines to LisbonExplore the most affordable flight options available from Des Moines to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Des Moines to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:13 am -
2 stops19h 47m
Thu 11/1910:00 am -
2 stops16h 43m
Deal found 9/21![Delta logo]()
$600
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:22 am -
2 stops22h 18m
Wed 11/115:00 am -
2 stops23h 35m
Deal found 9/22![Delta logo]()
$637
This Expedia deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:57 am -
2 stops30h 13m
Fri 11/1311:30 am -
2 stops15h 43m
Deal found 9/22![KLM logo]()
$679
This Ticket deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:50 pm -
2 stops15h 20m
Sat 11/145:00 am -
2 stops17h 49m
Deal found 9/23![Multiple Airlines logo]()
$682
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:57 am -
2 stops15h 03m
Sat 11/145:30 am -
2 stops21h 13m
Deal found 9/23![Delta logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
3 stops18h 10m
Wed 11/115:00 am -
2 stops35h 32m
Deal found 9/20![United Airlines logo]()
$718
This Bravofly deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
2 stops22h 05m
Fri 11/135:00 am -
2 stops18h 28m
Deal found 9/22![Lufthansa logo]()
$724
This Travelocity deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:22 pm -
2 stops59h 43m
Tue 10/205:05 am -
2 stops24h 30m
Deal found 9/19![Multiple Airlines logo]()
$783
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:58 pm -
2 stops16h 07m
Sun 11/157:05 am -
2 stops17h 51m
Deal found 9/24![American Airlines logo]()
$805
This Iberia deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:58 pm -
2 stops20h 07m
Sun 11/158:45 pm -
2 stops28h 11m
Deal found 9/24![Iberia logo]()
$815
Best flights from Des Moines to LisbonDiscover carefully curated flight deals from Des Moines to Lisbon that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Des Moines to Lisbon that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:22 am -
2 stops22h 18m
Wed 11/115:00 am -
2 stops23h 35m
Deal found 9/22![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:00 am -
3 stops18h 10m
Thu 11/195:00 am -
2 stops18h 28m
Deal found 9/21![United Airlines logo]()
$718
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:57 am -
2 stops15h 03m
Sat 11/145:30 am -
2 stops21h 13m
Deal found 9/23![Delta logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
3 stops18h 10m
Wed 11/115:00 am -
2 stops35h 32m
Deal found 9/20![United Airlines logo]()
$718
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/178:00 am -
3 stops18h 10m
Mon 3/155:00 am -
2 stops21h 17m
Deal found 9/21![United Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/173:00 pm -
2 stops35h 10m
Sun 3/1410:50 am -
2 stops54h 44m
Deal found 9/23![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/198:00 am -
3 stops18h 10m
Fri 2/2612:20 pm -
2 stops14h 57m
Deal found 9/20![United Airlines logo]()
$736
Last-minute flights from Des Moines to LisbonDiscover last-minute flight deals from Des Moines to Lisbon. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Lisbon. Data last updated September 24, 2026 and is based on user searches.
This United deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am -
2 stops20h 20m
Tue 9/2911:25 am -
2 stops42h 10m
Deal found 9/23![Multiple Airlines logo]()
$1,392
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:09 pm -
1 stop13h 56m
Tue 9/2911:05 am -
1 stop16h 31m
Deal found 9/23![American Airlines logo]()
$1,445
This Air Canada deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2711:27 am -
3 stops15h 53m
Tue 9/2911:25 am -
3 stops18h 10m
Deal found 9/23![Air Canada logo]()
$1,614
This Lufthansa deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:24 pm -
2 stops16h 21m
Tue 10/65:05 am -
2 stops18h 43m
Deal found 9/22![Lufthansa logo]()
$1,035
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:27 am -
3 stops15h 53m
Tue 10/611:25 am -
3 stops18h 10m
Deal found 9/22![Air Canada logo]()
$1,775
This Travelocity deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:22 pm -
2 stops59h 43m
Tue 10/205:05 am -
2 stops24h 30m
Deal found 9/19![Multiple Airlines logo]()
$783
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:15 pm -
1 stop13h 50m
Tue 10/207:10 am -
2 stops17h 50m
Deal found 9/19![American Airlines logo]()
$1,680
This AirNGo deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:55 pm -
2 stops22h 40m
Thu 10/296:05 am -
2 stops40h 22m
Deal found 9/23![Lufthansa logo]()
$830
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:01 pm -
2 stops15h 49m
Thu 10/2911:05 am -
1 stop30h 40m
Deal found 9/23![American Airlines logo]()
$899
One-way flights from Des Moines to LisbonSearch for one-way flight options from Des Moines to Lisbon. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Des Moines to Lisbon. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Expedia deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:25 am -
2 stops20h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![British Airways logo]()
$507
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:26 pm -
3 stops58h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$520
This Kissandfly.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:05 am -
2 stops32h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Aer Lingus logo]()
$547
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:27 am -
3 stops15h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Air Canada logo]()
$760
Find flight deals from Des Moines to Lisbon
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Lisbon (LIS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $600 (Delta) |
One-way from | $507 (Expedia) |
Popular in | June |
Cheapest in | April |
Average price | $1,079 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Des Moines to Lisbon that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Fri 11/6
9:25 am-12:05 pm
2 stops20h 40m
Lisbon Humberto Delgado
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$507
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Fri 11/6
3:26 pm-7:45 am
3 stops58h 19m
Lisbon Humberto Delgado
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$520
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Tue 9/29
7:05 am-9:35 pm
2 stops32h 30m
Lisbon Humberto Delgado
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$547
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Wed 11/4
10:22 am-2:40 pm
2 stops22h 18m
Lisbon Humberto Delgado
Wed 11/11
5:00 am-10:35 pm
2 stops23h 35m
$637
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Sat 11/7
10:57 am-8:00 am
2 stops15h 03m
Lisbon Humberto Delgado
Sat 11/14
5:30 am-8:43 pm
2 stops21h 13m
$711
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Mon 11/9
8:00 am-8:10 am
3 stops18h 10m
Lisbon Humberto Delgado
Thu 11/19
5:00 am-5:28 pm
2 stops18h 28m
$718
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Wed 11/4
8:00 am-8:10 am
3 stops18h 10m
Lisbon Humberto Delgado
Wed 11/11
5:00 am-10:32 am
2 stops35h 32m
$718
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Sun 1/17
8:00 am-8:10 am
3 stops18h 10m
Lisbon Humberto Delgado
Mon 3/15
5:00 am-9:17 pm
2 stops21h 17m
$723
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Sun 1/17
3:00 pm-8:10 am
2 stops35h 10m
Lisbon Humberto Delgado
Sun 3/14
10:50 am-12:34 pm
2 stops54h 44m
$731
Des MoinesLisbon
DSM Des Moines - LIS Lisbon Humberto Delgado
DSMLIS
Des Moines
Fri 2/19
8:00 am-8:10 am
3 stops18h 10m
Lisbon Humberto Delgado
Fri 2/26
12:20 pm-9:17 pm
2 stops14h 57m
$736
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Lisbon
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Lisbon in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Lisbon flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Des Moines-Lisbon flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Des Moines-Lisbon flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Lisbon flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Lisbon flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Lisbon
Have a flexible travel schedule? Discover the best time to fly to Lisbon from Des Moines with our price prediction graph.
DSM-LIS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Lisbon
Reviews of airlines servicing Lisbon
Get insights into the airlines that provide service to Lisbon. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lisbon. Reviews last updated September 24, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Des Moines to Lisbon. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Food
6.7
Crew
8.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Entertainment
7.1
Food
6.7
Crew
8.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Entertainment
7.1
Food
6.7
Crew
8.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Lisbon?
Book flights to Lisbon if you plan to visit one of these locationsFátima
Ericeira
Oeiras
Torres Vedras
Beja
Nazaré
Colares
Sesimbra
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Des Moines and Lisbon flights
Browse other Des Moines and Lisbon flight options. Last updated on September 24, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Lisbon
Discover the top 2 airlines that operate flights from Des Moines to Lisbon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$528 | Average$1,134 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$545 | Average$964 | FlexibilityNo cancel fee | On-time69% |